CN102696621B - Bactericidal composition containing difenodiconazole and prothioconazole - Google Patents
Bactericidal composition containing difenodiconazole and prothioconazole Download PDFInfo
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- CN102696621B CN102696621B CN 201210178554 CN201210178554A CN102696621B CN 102696621 B CN102696621 B CN 102696621B CN 201210178554 CN201210178554 CN 201210178554 CN 201210178554 A CN201210178554 A CN 201210178554A CN 102696621 B CN102696621 B CN 102696621B
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- prothioconazoles
- phenylate
- azoles
- wheat
- bactericidal composition
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Landscapes
- Agricultural Chemicals And Associated Chemicals (AREA)
Abstract
The invention relates to a bactericidal composition which contains active components, such as difenodiconazole and prothioconazole by a weight ratio of (100:1) to (1:100), and also relates to a bactericidal preparation agent containing the composition, as well as the application in preventing and curing powdery mildew, banded sclerotial blight and rust disease. According to the invention, the results of a plenty of bioassay and field efficacy trials show that the bactericidal composition has an excellent and obvious controlling effect in preventing the powdery mildew, banded sclerotial blight and rust disease of wheat.
Description
Technical field
The invention belongs to the composition pesticide field, specifically the bactericidal composition take the two azoles of phenylate and prothioconazoles as active ingredient.Be mainly used in preventing and treating the bactericidal composition of powdery mildew of wheat and barley, banded sclerotial blight, rust.
Background technology
Powdery mildew, banded sclerotial blight, rust are very important diseases on the crops such as wheat class.Be a kind of worldwide disease as wheat powdery mildew, all having in the wheat belt, various places distributes causes harm.The main harm blade, leaf sheath, stem stalk when serious, the wheat head also can occur.Killed wheatland seriously loses up to 20 ~ 30%, and indivedual plot even reach more than 50%; Wheat sharp eyespot occurs general and serious, main harm stem culm base, and the oval moire shape taupe scab of formation on the leaf sheath of basal part of stem 1～3 joint, when seriously ill, stem is withered, produces dead ears, easily lodges when meeting wind and rain.Increase the weight of year by year in the middle and lower reach of Yangtze River and Plain of Huanghua Area Mai Qu, the serious plot underproduction 50% left and right, indivedual plot even have no harvest; Wheat rust itemize rust, leaf rust, stem rust three types mainly betide Winter Wheat Area and the spring wheat districts, northwest such as northwest, southwest, the Yellow River and Huai He River.But the popular time underproduction 20 ~ 30%, serious plot even has no harvest.This three classes disease usually causes the significant loss of wheat crops.
The two azoles (Difenodiconazole) of phenylate, chemical name: 2-[2-chloro-4-(4-chlorobenzene oxygen) phenyl]-1, two (1H-1,2,4-the triazol-1-yl)-2-propyl alcohol of 3-, CAS registration number: 930581-38-7.Have following structural formula:
Prothioconazoles (Prothioconazole) prothioconazoles is a kind of New-type wide-spectrum triazolinthione series bactericidal agent of Beyer Co., Ltd development, not only has good systemic activity, excellent protection, treats and root out activity, and the lasting period is long.Prothioconazoles not only has good safety to crop, and preventing disease theraping effect is good, and volume increase is obvious, compares with triazole bactericidal agent, and prothioconazoles has the more sterilization of wide spectrum and lives in.Be mainly used in preventing and treating numerous diseases such as cereal crop such as wheat, barley, rape, peanut, paddy rice and legume crop.Almost all wheat class diseases there is good control efficiency, as the powdery mildew of Wheat and barley, banded sclerotial blight, fusarium wilt, leaf spot, rust, stalk break, net blotch, moire disease etc.Can also prevent and treat the soil-borne disease of rape and peanut, as stalk break, and main foliage disease, as gray mold, black spot, brown spot, balck shank, stalk break and rust etc.
But, along with the prolongation of medication history, and the unreasonable use of agricultural chemicals, cause the drug-fast generation of pathogen of crop, and more serious in recent years, and single medicament constantly descends to the preventive effect of crop pest.Therefore, in the urgent need to new pesticidal preparations, can effectively prevent and treat for example generation of powdery mildew, banded sclerotial blight, rust of crop pest on the one hand, on the other hand, can also reduce dosage, delay the pathogen development of drug resistance.
Summary of the invention
For addressing the above problem, the invention provides a kind of synergistic sterilizing composition, it can be used in the control of wheat powdery mildew, banded sclerotial blight, rust, and not only bactericidal effect is good, drug cost is low, and is difficult for developing immunity to drugs.。
For reaching goal of the invention the present invention by the following technical solutions:
A kind of bactericidal composition is characterized in that: contain the two azoles of active component phenylate and prothioconazoles, the weight ratio of the two azoles of described phenylate and prothioconazoles is 100:1 ~ 1:100.
The weight ratio of the two azoles of above-mentioned phenylate and prothioconazoles is preferably 10:1 ~ 1:10.
Described composition can effectively be prevented and treated the various agricultural disease, and such as powdery mildew, banded sclerotial blight, rust etc. all shows synergistic function.
Above-mentioned active component can directly provide with combining form, namely with the form of complex preparation; Also can provide with the single dose dosage form respectively, before using, bucket (tank) is mixed.
When composition of the present invention is prepared into complex preparation, can be according to method known in those skilled in the art (for example in " formulations of pesticide process technology ", the Liu Bulin chief editor, the preparation processing method that relates in second edition, be hereby incorporated by), be mixed with the upper any formulation that allows of agricultural, preferred suspending agent, aqueous emulsion, microemulsion, wetting powder or water dispersible granules.
Wherein, described complex preparation contains the above-mentioned bactericidal composition based on 0.1% ~ 90% percentage by weight of total formulation weight amount, and all the other are acceptable carrier and auxiliary agent on agricultural chemicals.Be preferably the above-mentioned bactericidal composition that contains based on 10% ~ 80% percentage by weight of total formulation weight amount.More preferably contain the above-mentioned bactericidal composition based on total formulation weight amount 20% ~ 60% percentage by weight.
Concrete:
When being mixed with water dispersible granules, auxiliary agent comprises:
Dispersant: be selected from polycarboxylate, lignosulfonates, alkylnaphthalene sulfonate, alkylnaphthalene sulfonate formaldehyde condensation products, consumption is the 1-10% of total formulation weight amount, preferred 3-7%;
Wetting agent: be selected from polyoxyethylene alcohol, alkyl sulfate, alkylsulfonate, naphthalene sulfonate etc., consumption is the 1-10% of total formulation weight amount, preferred 2-7%;
Disintegrant: be selected from ammonium sulfate, urea, sucrose, glucose, citric acid, succinic acid, sodium bicarbonate, consumption is the 0.1-10% of total formulation weight amount, preferred 1-5%;
Binding agent: be selected from diatomite, corn starch, PVA, carboxymethyl (ethyl) cellulose family and microcrystalline cellulose class, consumption is the 0.1-10% of total formulation weight amount, preferred 1-5%;
Surplus is filler, and it is selected from diatomite, kaolin, white carbon, fine particle calcium carbonate, sepiolite, talcum powder, attapulgite, potter's clay etc.
When being mixed with wetting powder, auxiliary agent comprises:
Dispersant: be selected from polycarboxylate, lignosulfonates, alkylnaphthalene sulfonate, alkylnaphthalene sulfonate formaldehyde condensation products, consumption is the 1-10% of total formulation weight amount, preferred 3-7%;
Wetting agent: be selected from alkyl sulfate, alkylsulfonate, naphthalene sulfonate, consumption is the 1-10% of total formulation weight amount, preferred 3-7%;
Surplus is filler, and it is selected from diatomite, kaolin, white carbon, fine particle calcium carbonate, talcum powder, attapulgite, potter's clay etc.
When being mixed with suspending agent, auxiliary agent comprises:
Dispersant: be selected from polycarboxylate, lignosulfonates, alkylnaphthalene sulfonate, fatty alcohol-polyoxyethylene ether, consumption is the 1-10% of total formulation weight amount, preferred 3-7%;
Wetting agent: be selected from the poly-basic ether formaldehyde condensation products sulphate of alkylphenol-polyethenoxy, alkylphenol-polyethenoxy base ether phosphate, phenethyl phenol polyethenoxy base ether phosphate, alkyl sulfate, alkylsulfonate, naphthalene sulfonate, fatty alcohol-polyoxyethylene ether, consumption is the 1-10% of total formulation weight amount, preferred 3-7%;
Thickener: be selected from xanthans, aluminium-magnesium silicate, bentonite, consumption is the 0.1-10% of total formulation weight amount, preferred 1-5%;
Preservative: be selected from benzoic acid, Sodium Benzoate, BIT(1, the 2-benzisothiazole-3-ketone), consumption is the 0.1-10% of total formulation weight amount, preferred 0.3-2%;
Defoamer: be silicone based defoamer, consumption is the 0.1-10% of total formulation weight amount, preferred 0.4-1.0%;
Antifreezing agent: be selected from ethylene glycol, propane diols, glycerine, urea, inorganic salts such as sodium chloride, consumption is the 0.1-10% of total formulation weight amount, preferred 1-5%.
Surplus is water.
When being mixed with aqueous emulsion, auxiliary agent comprises:
Emulsifier: be selected from Nonyl pheno (EO=10) ether phosphate, triphen ethyl-phenol polyoxyethylene ether phosphate (agriculture breast 600# phosphate), Nongru-700 #, agriculture breast 2201#, Span-60#, emulsifier T-60, TX-10, agriculture breast 1601#, agriculture breast 600#, agriculture breast 400#, consumption is the 1-10% of total formulation weight amount, preferred 2-8%;
Solvent: be selected from dimethylbenzene, toluene, cyclohexanone, solvent naphtha (trade mark: S-150, S-180, S-200), consumption is the 1-30% of total formulation weight amount, preferred 5-20%;
Stabilizing agent: be selected from triphenyl phosphite, epoxychloropropane, consumption is the 0.1-10% of total formulation weight amount, preferred 0.1-5%;
Antifreezing agent: be selected from ethylene glycol, propane diols, glycerine, urea, inorganic salts such as sodium chloride, consumption is the 0.1-10% of total formulation weight amount, preferred 1-5%;
Thickener: be selected from xanthans, bentonite, aluminium-magnesium silicate, consumption is the 0.1-10% of total formulation weight amount, preferred 1-5%;
Preservative: be selected from BIT(1, the 2-benzisothiazole-3-ketone), benzoic acid, Sodium Benzoate, consumption is the 0.1-10% of total formulation weight amount, preferred 0.3-2.0%;
Surplus is water.
When being mixed with microemulsion, auxiliary agent comprises:
Emulsifier: be selected from calcium dodecyl benzene sulfonate (agriculture breast 500#), Nongru-700 #, agriculture breast 2201#, this dish-60#, Tween-80, TX-10, agriculture breast 1601, agriculture breast 600#, agriculture breast 400#, polyoxyethylene nonylphenol ether phosphate, consumption is the 5-25% of total formulation weight amount, preferred 10-20%;
Cosolvent: be selected from methyl alcohol, isopropyl alcohol, n-butanol, ethanol, consumption is the 0.1-10% of total formulation weight amount, preferred 1-5%;
Solvent: be selected from cyclohexanone, 1-METHYLPYRROLIDONE, dimethylbenzene, toluene, solvent naphtha (trade mark: S-150, S-180, S-200), consumption is the 1-30% of total formulation weight amount, preferred 5-20%;
Stabilizing agent is selected from triphenyl phosphite, epoxychloropropane,, consumption is the 0.1-10% of total formulation weight amount, preferred 1-5%;
Antifreezing agent: be selected from ethylene glycol, propane diols, glycerine, urea, inorganic salts such as sodium chloride, consumption is the 0-10% of total formulation weight amount, preferred 1-5%;
Thickener: be selected from xanthans, bentonite, aluminium-magnesium silicate, consumption is the 0-10% of total formulation weight amount, preferred 1-5%;
Preservative: be selected from BIT(1, the 2-benzisothiazole-3-ketone), benzoic acid, Sodium Benzoate, consumption is the 0-10% of total formulation weight amount, preferred 0.3-2.0%;
Water surplus.
Compared with prior art, the beneficial effect of the present invention's generation is:
(1) compare with single dose, bactericidal composition of the present invention has significant synergistic effect to disease, has improved bactericidal effect;
(2) reduce drug cost, environmental contamination reduction and residue of pesticide;
(3) composition is comprised of the active ingredient of different mechanism of action, and action site increases, and is conducive to overcome and delays the drug-fast generation of germ.
Embodiment
Below in conjunction with specific embodiment, the present invention is further illustrated, but do not limit the invention to these embodiments.One skilled in the art would recognize that the present invention contained all alternatives, improvement project and the equivalents that may comprise in claims scope.
1 indoor bioassay embodiment
Example 1.1: the two azoles of phenylate and the composite Toxicity Determination to wheat powdery mildew of prothioconazoles
Test target wheat powdery mildew (Erysiphe graminis) is cultivated by the long-term live body of this laboratory and is selected susceptible variety (raising wheat No. 6) potted plant, treat that seedling grows to 2 leaves～3 leaf phases, naturally, dries after spraying is processed, the fresh spore of Powdery Mildew that the wheat leaf blade of falling ill was produced in upper 24 hour is evenly shaken off to be inoculated on 2～3 potted plant wheat seedlings of leaf phase that chemicals treatment crosses.Postvaccinal examination material moves to 20 ℃, relative moisture 80% left and right controllable greenhouse glass room is interior cultivates.Note keeping basin soil moistening every day, investigate according to the classification of blank incidence about 7 days.
The investigation grade scale:
0 grade: anosis;
1 grade: lesion area accounts for below 5% of one-piece blade area;
3 grades: lesion area accounts for 6% ~ 15% of one-piece blade area;
5 grades: lesion area accounts for 16% ~ 25% of one-piece blade area;
7 grades: lesion area accounts for 26% ~ 50% of one-piece blade area;
9 grades: lesion area accounts for more than 50% of one-piece blade area.
The preventive effect computational methods:
Co-toxicity coefficient computational methods: EC that each that will measure according to Sun Yunpei (Y-P Sun) method [8] processed
50Be converted into actual poison exponent (ATI); According to the proportioning of mixture, obtain theoretical poison exponent (TTI), calculate the co-toxicity coefficient (CTC) of mixture by following formula.
The content (%) of toxicity index * B in mixed of the content (%) of toxicity index * A of theoretical mixed toxicity index (TTI)=A in mixed+B
If co-toxicity coefficient greater than 120, shows, synergistic effect is arranged; If be starkly lower than 100, be indicated as antagonism; Between 100～120, be indicated as summation action.
The two azoles of table 1 phenylate and the composite Toxicity Determination result to wheat powdery mildew of prothioconazoles
The data demonstration of table 1, the two azoles of phenylate and the co-toxicity coefficient of prothioconazoles under described proportioning show obvious synergistic effect all greater than 120.
Example 1.2: the two azoles of phenylate and the composite Toxicity Determination to wheat sharp eyespot of prothioconazoles
Test target rhizoctonia cerealis (Rhizoctonia cerealis) is cultivated by the long-term live body of this laboratory, selects susceptible variety (raising wheat No. 6) pot-culture method.Select two leaves wholeheartedly, potted plant wheat seeding that growing way is consistent, spraying is dried after processing naturally, 24h inoculates the left and right, is spraying banded sclerotial blight mycelia piece of every basin wheat seeding base portion central authorities' clamping connection of medicine, the bacterium piece does not contact with basin is native.Postvaccinal examination material moves in humidistat to be cultivated, 20 ℃ of temperature, and every day is observed the wheat seedling growth situation, investigation prevention effect when after 5 days, blank is fully fallen ill in humidity 80% left and right.
Investigation method and grade scale are as follows:
0 grade: do not fall ill;
1 grade: the first leaf sheath morbidity;
3 grades: the first blade and the morbidity of the second leaf sheath;
5 grades: the second blade and the morbidity of the 3rd leaf sheath;
7 grades: whole strain morbidity.
The content (%) of toxicity index * B in mixed of the content (%) of toxicity index * A of theoretical mixed toxicity index (TTI)=A in mixed+B
If co-toxicity coefficient greater than 120, shows, synergistic effect is arranged; If be starkly lower than 100, be indicated as antagonism; Between 100～120, be indicated as summation action.
The two azoles of table 2 phenylate and the composite Toxicity Determination result to wheat sharp eyespot of prothioconazoles
The data demonstration of table 2, the two azoles of phenylate and the co-toxicity coefficient of prothioconazoles under described proportioning show obvious synergistic effect all greater than 120.
Example 1.3: the two azoles of phenylate and the composite Toxicity Determination to wheat rust of prothioconazoles
Experiment target is designated as wheat leaf rust pathogen (Puccinia recondita), and wheat breed is for raising wheat No. 6, and every basin is selected approximately 10 strain wheat seedings, the 3-4 leaf phase to be grown to is standby, reagent agent and proportioning medicament are mixed with the liquid that presets concentration, and 4 repetitions are established in the processing of spraying, every processing.Get the wheat leaf blade that covers with the leaf rust bacterium after 24h, wash gently with sterile water and get surperficial fresh spore, filter with double gauze, making spore concentration is the suspension of 100,000/ml left and right, spray inoculation (pressure 0.1MPa).After connecing bacterium wheat seeding is under 20 ℃ of conditions, moisturizing one day, then put back to the greenhouse, and when contrasting abundant morbidity, carry out state of an illness investigation by field control effectiveness test criterion grade scale after the week, refer to calculate preventive effect by disease.Obtain EC with return law of the straight line
50
Investigation method and grade scale are as follows:
0 grade: anosis;
1 grade: lesion area accounts for below 5% of one-piece blade area;
3 grades: lesion area accounts for 6% ~ 25% of one-piece blade area;
5 grades: lesion area accounts for 26% ~ 50% of one-piece blade area;
7 grades: lesion area accounts for 51% ~ 75% of one-piece blade area;
9 grades: lesion area accounts for more than 76% of one-piece blade area.
Drug effect is calculated
On the basis of chemical control efficient, carry out the data analysis statistics with " DPS data handling system " 3.11 professional versions, obtain regression line, EC
50, correlation coefficient.EC that each that will measure according to Sun Yunpei (Y-PSun) method processed
50Be converted into actual poison exponent (ATI); According to the proportioning of mixture, calculate theoretical poison exponent (TTI), calculate the co-toxicity coefficient (CTC) of mixture by following formula.
The content (%) of toxicity index * B in mixed of the content (%) of toxicity index * A of theoretical mixed toxicity index (TTI)=A in mixed+B
If co-toxicity coefficient greater than 120, shows, synergistic effect is arranged; If it is following to be starkly lower than 100(80), be indicated as antagonism; Between 100～120, be indicated as summation action.
The two azoles of table 3 phenylate and the composite Toxicity Determination result to wheat rust of prothioconazoles
The data demonstration of table 3, the two azoles of phenylate and the co-toxicity coefficient of prothioconazoles under described proportioning show obvious synergistic effect all greater than 120.
2 FORMULATION EXAMPLE
In all preparation proportionings, percentage composition is mass percent.
The two azoles prothioconazoles suspending agents of embodiment 2.1:30% phenylate
Take the two former medicines of azoles of 10g phenylate, the former medicine of 20g prothioconazoles, 4g FS3000(Phosphate Anionic Surfactants), 1g SXC(sulfonate anionic surfactant), 0.1g xanthans, 1g aluminium-magnesium silicate, 5g ethylene glycol, 0.2g BIT(1, the 2-benzisothiazole-3-ketone), the organically-modified silica alkane of 0.3g defoamer, deionized water adds to 100g.Above-mentioned raw materials is joined shear 10min in high-shear emulsion machine, then after using the sand mill sand milling, obtain suspending agent.
The two azoles prothioconazoles suspending agents of embodiment 2.2:30% phenylate
Take the two former medicines of azoles of 15g phenylate, the former medicine of 15g prothioconazoles, 3.5g FS3000,1g JFC(fatty alcohol-polyoxyethylene ether), 0.2g xanthans, aluminium-magnesium silicate 1g, 5g ethylene glycol, 0.3g benzoic acid, the organically-modified silica alkane of 0.5g defoamer, deionized water adds to 100g.Above-mentioned raw materials is joined shear 10min in high-shear emulsion machine, then after using the sand mill sand milling, obtain suspending agent.
The two azoles prothioconazoles water dispersible granules of embodiment 2.3:45% phenylate
Take the two former medicines of azoles of 15g phenylate, the former medicine of 30g prothioconazoles, 4g NNO(alkylnaphthalene sulfonate formaldehyde condensation products), 2g Nekal BX (nekal), 3gK-12(lauryl sodium sulfate), 5g carboxymethyl (ethyl) cellulose, 3g diatomite, 5g glucose, kaolin add to 100g.Mix, after air-flow crushing, carry out granulation in comminutor, then dry, screening namely gets granular product.
The two azoles prothioconazoles water dispersible granules of embodiment 2.4:36% phenylate
Take the two former medicines of azoles of 6g phenylate, the former medicine of 30g prothioconazoles, 4g NNO(alkylnaphthalene sulfonate formaldehyde condensation products), 2g Nekal BX (nekal), 3gK-12(lauryl sodium sulfate), 5g carboxymethyl (ethyl) cellulose, 2g diatomite, 5g glucose, kaolin add to 100g.Mix, after air-flow crushing, carry out granulation in comminutor, then dry, screening namely gets granular product.
The two azoles prothioconazoles wetting powders of embodiment 2.5:60% phenylate
Take the two former medicines of azoles of 40g phenylate, the former medicine of 20g prothioconazoles, 4gNNO, 2g Nekal BX, 5g white carbon, fine particle calcium carbonate and add to 100g.Mix, obtain product after pulverizing.
The two azoles prothioconazoles wetting powders of embodiment 2.6:80% phenylate
Take the two former medicines of azoles of 30g phenylate, the former medicine of 50g prothioconazoles, 5g calcium lignosulfonate, 3g Nekal BX, 3gK-12, kaolin and add to 100g.Mix, obtain product after pulverizing.
The two azoles prothioconazoles wetting powders of embodiment 2.7:30% phenylate
Take the two former medicines of azoles of 25g phenylate, the former medicine of 5g prothioconazoles, 4g calcium lignosulfonate, 3g Nekal BX, 3gK-12, kaolin and add to 100g.Mix, obtain product after pulverizing.
The two azoles prothioconazoles microemulsions of embodiment 2.8:10% phenylate
Take the two former medicines of azoles of 5g phenylate, the former medicine of 5g prothioconazoles, 8g Nongru-700 #, 5g agriculture breast 500#, 5g agriculture breast 1601#, 20g cyclohexanone, 5gN-methyl pyrrolidone, 5g n-butanol, through dissolve complete and mix, deionized water adds to 100g.After stirring, obtain product.
The two azoles prothioconazoles microemulsions of embodiment 2.9:11% phenylate
Take the two former medicines of azoles of 1g phenylate, the former medicine of 10g prothioconazoles, 8g Nongru-700 #, 5g agriculture breast 500#, 4g agriculture breast 1601#, 20g cyclohexanone, 5gN-methyl pyrrolidone, 5g n-butanol, through dissolve complete and mix, deionized water adds to 100g.After stirring, obtain product.
The two azoles prothioconazoles microemulsions of embodiment 2.10:30.3% phenylate
Take the two former medicines of azoles of 30g phenylate, the former medicine of 0.3g prothioconazoles, 8g Nongru-700 #, 5g agriculture breast 500#, 6g agriculture breast 1601#, 25g cyclohexanone, 6gN-methyl pyrrolidone, 5g n-butanol, through dissolve complete and mix, deionized water adds to 100g.After stirring, obtain product.
The two azoles aqueous emulsions of embodiment 2.11:20% prothioconazoles phenylate
Take the former medicine of 10g prothioconazoles, the two former medicines of azoles of 10g phenylate, 5g agriculture breast 2201#, 2g Nonyl pheno (EO=10) ether phosphate, 3g agriculture breast 600# acid phosphatide, 20g cyclohexanone, 10g solvent naphtha S 150, mixed dissolution obtains oil phase.With 5g ethylene glycol, 0.3g xanthans, 0.5g benzoic acid, deionized water adds to 100g, is made into water.Oil phase adds aqueous phase fully to mix, and after high-shear emulsifying, obtains product.
The two azoles aqueous emulsions of embodiment 2.12:11% prothioconazoles phenylate
Take the former medicine of 10g prothioconazoles, the two former medicines of azoles of 1g phenylate, 4g agriculture breast 2201#, 2g Nonyl pheno (EO=10) ether phosphate, 2g agriculture breast 600# acid phosphatide, 10g cyclohexanone, 10g solvent naphtha S150, mixed dissolution obtains oil phase.With 5g ethylene glycol, 0.3g xanthans, 0.5g benzoic acid, deionized water adds to 100g, is made into water.Oil phase adds aqueous phase fully to mix, and after high-shear emulsifying, obtains product.
The two azoles aqueous emulsions of embodiment 2.13:40.4% prothioconazoles phenylate
Take the former medicine of 0.4g prothioconazoles, the two former medicines of azoles of 40g phenylate, 6g agriculture breast 2201#, 2g Nonyl pheno (EO=10) ether phosphate, 3g agriculture breast 600# acid phosphatide, 25g cyclohexanone, 10g solvent naphtha S150, mixed dissolution obtains oil phase.With 5g ethylene glycol, 0.3g xanthans, 0.5g benzoic acid, deionized water adds to 100g, is made into water.Oil phase adds aqueous phase fully to mix, and after high-shear emulsifying, obtains product.
3 field trial application examples
Application examples 3.1, control wheat powdery mildew field control effectiveness test
The residential quarter of test medicine, contrast medicament and blank is processed and is adopted random district group to arrange, residential quarter area 20 square meters, 4 repetitions, each spraying control of booting stage and flowering initial stage 1 time.This tests the 7th day and investigation in 15 days of dispenser for the second time, adopts random five point samplings, gets 20 strains at every, upper 3 leaves (having boot leaf to comprise boot leaf) of the every strain of investigation.
The disease scale standard is as follows:
0 grade: without scab;
1 grade: lesion area accounts for below 5% of whole leaf area;
3 grades: lesion area accounts for 6% ~ 15% of whole leaf area;
5 grades: lesion area accounts for 16% ~ 25% of whole leaf area;
7 grades: lesion area accounts for 26% ~ 50% of whole leaf area;
9 grades: lesion area accounts for more than 51% of whole leaf area.
The drug effect computational methods:
According to investigation result, calculate disease index and preventive effect according to following (1), (2) formula.
In formula: CK
0, CK
1Be respectively the forward and backward disease index of blank district's dispenser; PT
0, PT
1Be respectively the forward and backward disease index of chemicals treatment district's medicine.
Table 4 control wheat powdery mildew field control effectiveness test result
Data show, the field efficacy of preparation of the present invention is significantly greater than the preventive effect of the two azoles SC of prior art 250g/L phenylate and 25% prothioconazoles SC.
Application examples 3.2 control wheat sharp eyespot field control effectiveness tests
Regulation according to medicine inspecting institute of the Ministry of Agriculture " GB/T 17980.108-2004 pesticide field efficacy medicine test criterion ()---bactericidal agent for preventing and treating wheat sharp eyespot ", the residential quarter of test medicine, contrast medicament and blank is processed and is adopted random district group to arrange, residential quarter area 15 square meters, repeat for 4 times, this test amounts to twice of dispenser.Be in their early stage during dispenser for the first time, execute medicine for the second time after 10 days.Diagonal 5 samplings in every experimental plot during investigation, the incidence of disease and withered dead ears rate are recorded in every some investigation 100 strains, record the disease grade.
The disease scale standard is as follows:
0 grade: do not fall ill;
1 grade: leaf sheath is fallen ill but the stem stalk is not fallen ill;
3 grades: the leaf sheath morbidity, and invade stem, but stem stalk scab ring stem less than 1/2;
5 grades: stem stalk scab ring stem surpasses 1/2, but non-lodging or fracture;
7 grades: withered, lodging, withered dead ears.
The drug effect computational methods:
According to investigation result, calculate disease index and preventive effect according to following (1), (2) formula.
In formula: CK
0, CK
1Be respectively the forward and backward disease index of blank district's dispenser; PT
0, PT
1Be respectively the forward and backward disease index of chemicals treatment district's medicine.
Table 5 control wheat sharp eyespot field control effectiveness test result
Data show, the field efficacy of preparation of the present invention is significantly greater than the preventive effect of the two azoles WDG of prior art 10% phenylate and 25% prothioconazoles SC.
Application examples 3.3 is prevented and treated the wheat rust field control effectiveness test
The residential quarter of test medicine, contrast medicament and blank is processed and is adopted random district group to arrange, residential quarter area 20 square meters, and 4 repetitions, this tests dispenser at the initial stage of a disease 1 time.After medicine, 30 days investigation drug effects, take 5 samplings of every residential quarter diagonal during investigation, and 20 leaves of every some investigation amount to 100 leaves, records the sick level of different disposal according to stage division, calculates disease index and control efficiency.
Grade scale:
0 grade: anosis
1 grade: lesion area accounts for below 5% of one-piece blade area;
3 grades: lesion area accounts for 6%～25% of one-piece blade area:
5 grades: lesion area accounts for the 26%-50% of one-piece blade area;
7 grades: lesion area accounts for 51%.75% of one-piece blade area;
9 grades: lesion area accounts for more than 76% of one-piece blade area.
According to investigation result, calculate disease index and preventive effect according to following (1), (2) formula.
In formula: CK
0, CK
1Be respectively the forward and backward disease index of blank district's dispenser; PT
0, PT
1Be respectively the forward and backward disease index of chemicals treatment district's medicine.
Table 6 is prevented and treated wheat rust field control effectiveness test result
Data show, the field efficacy of preparation of the present invention is significantly greater than the preventive effect of the two azoles WDG of prior art 10% phenylate and 25% prothioconazoles SC.
Comprehensively above-mentioned, a large amount of indoor biometricses and field control effectiveness test result show that bactericidal composition of the present invention all has outstanding preventive effect to wheat powdery mildew, banded sclerotial blight, rust etc., and its effect is non-obvious.
Claims (7)
1. bactericidal composition is characterized in that the weight ratio of the two azoles of phenylate and prothioconazoles is 1:100～100:1 take the two azoles of phenylate and prothioconazoles as active ingredient.
2. bactericidal composition according to claim 1, is characterized in that the weight ratio of the two azoles of phenylate and prothioconazoles is 1:10～10:1.
3. bactericidal composition according to claim 1 and 2 is characterized in that: described composition adds the upper acceptable auxiliary element of agricultural to be prepared into the upper acceptable preparation of agricultural.
4. composition according to claim 3, it is characterized in that: on described agricultural, acceptable preparation is suspending agent, aqueous emulsion, microemulsion, wetting powder or water dispersible granules.
5. composition according to claim 4, it is characterized in that: the weight content of active ingredient in described preparation is 0.1%～90%.
6. composition according to claim 5, it is characterized in that: the weight percent content of active ingredient in described preparation is 10%～80%.
7. composition claimed in claim 1 is used for the purposes of control crop powdery mildew of wheat and barley, banded sclerotial blight and rust.
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Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0111658A2 (en) * | 1980-06-02 | 1984-06-27 | Imperial Chemical Industries Plc | 1,3-Dihalopropan-2-ols |
| CN1923819A (en) * | 2006-10-12 | 2007-03-07 | 青岛科技大学 | compound containing aromatic ether and ditriazole and use thereof |
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2012
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Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0111658A2 (en) * | 1980-06-02 | 1984-06-27 | Imperial Chemical Industries Plc | 1,3-Dihalopropan-2-ols |
| CN1923819A (en) * | 2006-10-12 | 2007-03-07 | 青岛科技大学 | compound containing aromatic ether and ditriazole and use thereof |
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| CN102696621A (en) | 2012-10-03 |
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Address after: 311106 No. 172, Zhangjiadun Road, Tangqi Town, Linping District, Hangzhou, Zhejiang Patentee after: Zhejiang Yulong Pharmaceutical Co.,Ltd. Address before: No. 172, zhangjiadun Road, Tangqi Town, Yuhang District, Hangzhou City, Zhejiang Province, 311106 Patentee before: Hangzhou Udragon Chemical Co.,Ltd. |