CN102670753A - Method for processing wined white peony root - Google Patents
Method for processing wined white peony root Download PDFInfo
- Publication number
- CN102670753A CN102670753A CN201210191530XA CN201210191530A CN102670753A CN 102670753 A CN102670753 A CN 102670753A CN 201210191530X A CN201210191530X A CN 201210191530XA CN 201210191530 A CN201210191530 A CN 201210191530A CN 102670753 A CN102670753 A CN 102670753A
- Authority
- CN
- China
- Prior art keywords
- radix paeoniae
- paeoniae alba
- concocting method
- peony root
- white peony
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 238000000034 method Methods 0.000 title claims abstract description 82
- 244000236658 Paeonia lactiflora Species 0.000 title abstract description 5
- 235000008598 Paeonia lactiflora Nutrition 0.000 title abstract description 5
- 239000003814 drug Substances 0.000 claims abstract description 48
- 239000000463 material Substances 0.000 claims abstract description 30
- 238000010438 heat treatment Methods 0.000 claims abstract description 10
- VYQNWZOUAUKGHI-UHFFFAOYSA-N monobenzone Chemical compound C1=CC(O)=CC=C1OCC1=CC=CC=C1 VYQNWZOUAUKGHI-UHFFFAOYSA-N 0.000 claims description 66
- 239000012808 vapor phase Substances 0.000 claims description 7
- 229940079593 drug Drugs 0.000 abstract description 11
- 230000000202 analgesic effect Effects 0.000 abstract description 6
- 238000004519 manufacturing process Methods 0.000 abstract description 6
- 230000000144 pharmacologic effect Effects 0.000 abstract description 3
- 238000001816 cooling Methods 0.000 abstract 1
- 238000006073 displacement reaction Methods 0.000 abstract 1
- 230000008569 process Effects 0.000 description 18
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 12
- 238000012360 testing method Methods 0.000 description 10
- 241000699670 Mus sp. Species 0.000 description 9
- 210000002784 stomach Anatomy 0.000 description 8
- 230000008961 swelling Effects 0.000 description 7
- QTBSBXVTEAMEQO-UHFFFAOYSA-N Acetic acid Chemical compound CC(O)=O QTBSBXVTEAMEQO-UHFFFAOYSA-N 0.000 description 5
- 241000699666 Mus <mouse, genus> Species 0.000 description 5
- 238000002360 preparation method Methods 0.000 description 5
- 230000004044 response Effects 0.000 description 5
- 238000010998 test method Methods 0.000 description 5
- 230000003110 anti-inflammatory effect Effects 0.000 description 4
- 230000001939 inductive effect Effects 0.000 description 4
- -1 Dichlorodiphenyl Acetate Chemical compound 0.000 description 3
- 238000012449 Kunming mouse Methods 0.000 description 3
- 230000000694 effects Effects 0.000 description 3
- 238000005516 engineering process Methods 0.000 description 3
- YKRGDOXKVOZESV-WRJNSLSBSA-N Paeoniflorin Chemical compound C([C@]12[C@H]3O[C@]4(O)C[C@](O3)([C@]1(C[C@@H]42)O[C@H]1[C@@H]([C@@H](O)[C@H](O)[C@@H](CO)O1)O)C)OC(=O)C1=CC=CC=C1 YKRGDOXKVOZESV-WRJNSLSBSA-N 0.000 description 2
- 241000218201 Ranunculaceae Species 0.000 description 2
- 229960000583 acetic acid Drugs 0.000 description 2
- 230000009471 action Effects 0.000 description 2
- 230000033228 biological regulation Effects 0.000 description 2
- 230000037396 body weight Effects 0.000 description 2
- 230000008859 change Effects 0.000 description 2
- 239000003153 chemical reaction reagent Substances 0.000 description 2
- 238000005520 cutting process Methods 0.000 description 2
- 239000012153 distilled water Substances 0.000 description 2
- 238000007689 inspection Methods 0.000 description 2
- 239000012567 medical material Substances 0.000 description 2
- YKRGDOXKVOZESV-UHFFFAOYSA-N paeoniflorin Natural products O1C(C)(C2(CC34)OC5C(C(O)C(O)C(CO)O5)O)CC3(O)OC1C24COC(=O)C1=CC=CC=C1 YKRGDOXKVOZESV-UHFFFAOYSA-N 0.000 description 2
- 238000012372 quality testing Methods 0.000 description 2
- 230000001629 suppression Effects 0.000 description 2
- XOMKZKJEJBZBJJ-UHFFFAOYSA-N 1,2-dichloro-3-phenylbenzene Chemical group ClC1=CC=CC(C=2C=CC=CC=2)=C1Cl XOMKZKJEJBZBJJ-UHFFFAOYSA-N 0.000 description 1
- QTBSBXVTEAMEQO-UHFFFAOYSA-M Acetate Chemical compound CC([O-])=O QTBSBXVTEAMEQO-UHFFFAOYSA-M 0.000 description 1
- 208000032023 Signs and Symptoms Diseases 0.000 description 1
- 229910000831 Steel Inorganic materials 0.000 description 1
- 235000011054 acetic acid Nutrition 0.000 description 1
- 230000004069 differentiation Effects 0.000 description 1
- 230000000857 drug effect Effects 0.000 description 1
- 238000001035 drying Methods 0.000 description 1
- 210000005069 ears Anatomy 0.000 description 1
- 238000005265 energy consumption Methods 0.000 description 1
- 238000000556 factor analysis Methods 0.000 description 1
- 239000003500 flue dust Substances 0.000 description 1
- 239000012530 fluid Substances 0.000 description 1
- 239000012362 glacial acetic acid Substances 0.000 description 1
- 239000012535 impurity Substances 0.000 description 1
- 230000002401 inhibitory effect Effects 0.000 description 1
- 238000002347 injection Methods 0.000 description 1
- 239000007924 injection Substances 0.000 description 1
- 239000000203 mixture Substances 0.000 description 1
- 230000008506 pathogenesis Effects 0.000 description 1
- 238000007619 statistical method Methods 0.000 description 1
- 239000010959 steel Substances 0.000 description 1
- 238000003860 storage Methods 0.000 description 1
- 231100000419 toxicity Toxicity 0.000 description 1
- 230000001988 toxicity Effects 0.000 description 1
Landscapes
- Medicines Containing Plant Substances (AREA)
Abstract
The invention relates to a method for processing wined white peony root, which can be applied to standard mass production and operation and comprises the steps of: taking a clean white peony root piece, placing in a vacuum gas phase displacement type drug moistening machine, vacuumizing to ensure that the relative vacuum degree is up to -70-(-80) KPa, maintaining the vacuum degree unchanged, adding yellow wine, recovering to the normal pressure, carrying out covered moistening, flatly laying the material on a tray, putting in a microwave oven to heat at a microwave frequency of 2450+/-50MHz, turning over the material 1-2 times during the heating, taking out the material, cooling at the end to obtain a finished product. The method for processing the wined white peony root, disclosed by the invention, has the advantages of short consuming time and no difference in product quality and analgesic pharmacological activity from a traditional method.
Description
Technical field
The present invention relates to a kind of concocting method of Chinese medicine, especially a kind of concocting method of Radix Paeoniae Alba.
Background technology
Chinese medicine just can be used as medicine after must passing through and concocting, and this is characteristics of middle medical drugs, also is a big characteristic of Chinese medicine and pharmacy.Chinese medicine processing is according to Chinese medical theory, according to the needs and the medicine self property of determination of treatment based on pathogenesis obtained through differentiation of symptoms and signs medication, and the demands of different of adjustment, preparation, a pharmaceutical technology of being taked.
The purpose of Chinese medicine processing usually comprises the following aspects: reduce or eliminate the toxicity or the side effect of medicine; Change or relax the performance of medicine; Medicament curative effect enhancement; Change or strengthen pharmaceutically-active position and trend; Be convenient to adjust and preparation; Help storage and preserve drug effect etc.
The classification of Chinese medicine is a lot, and kind is numerous and diverse, and the various places concocting method is very not consistent yet.Produce because the restriction of historical conditions, processing procedure belong to the handicraft workshop formula more, be difficult to adapt to the big requirement of producing of current modernization, therefore study processing technique, improving processing procedure is the task of top priority.
The medical material Radix Paeoniae Alba is the ranunculaceae plant Radix Paeoniae
Paeonia lactifloraPall. dry root.
Clean Radix Paeoniae Alba sheet is the thin slice after the selected impurity of the medical material Radix Paeoniae Alba, moistening, the cutting.
The decoction pieces Radix Paeoniae Alba is the processing processed product of clean Radix Paeoniae Alba sheet.
" Pharmacopoeia of People's Republic of China (2010 editions) " record: Radix Paeoniae Alba, get Radix Paeoniae Alba sheet, process method (appendix II D) according to wine and fry to little yellow.
The traditional Chinese medical science thinks that the Radix Paeoniae Alba can reduce humble and shabby property after wine is processed, be good at and middle emergency.
In the prior art, it is workshop-based that many genus are produced in the process of preparing Chinese medicine of Radix Paeoniae Alba, can't satisfy the requirement of big production standardization.With operator's experience control, difficulty is big entirely for factors such as the duration and degree of heating, temperature, time in the traditional handicraft, and product quality usually can be uneven because the operator is different; Flue dust is big during operation, pollutes working environment; Operating time is long, and energy consumption is big.
Summary of the invention
Technical problem to be solved by this invention provides a kind of concocting method that is applicable to the Radix Paeoniae Alba of normalizing operation, weak point consuming time.
In order to solve the problems of the technologies described above, the present invention proposes following technical scheme.
Get clean Radix Paeoniae Alba sheet, insert the vacuum vapor-phase replacement type medicine processing device, evacuation make the relative vacuum degree reach-70KPa is to-80KPa, keeps the constant adding yellow wine of vacuum; Add the quality of yellow wine and the proportionate relationship of above-mentioned clean Radix Paeoniae Alba tablet quality is 0.1:1, recover normal pressure, moistening 20-30min is tiled in above-mentioned material on the pallet; Material thickness is 1.0-2.0cm, inserts in the microwave oven and heats, microwave frequency 2450 ± 50MHz, interior temperature 120-140 ℃ of stove; Heating 8-12min, during material turning 1-2 time, during end; Take out material, cool, promptly get.
Said relative vacuum degree is-75KPa.
The time of said moistening is 25min.
The said material thickness that is tiled on the pallet is 1.5cm.
Temperature is 130 ℃ in the said microwave oven.
Said microwave oven heat time heating time is 10min.
Adopt the Processing wine Radix Paeoniae Alba of the present invention, weak point consuming time is more suitable for the big production of standardization, and its technique effect can be through following evidence.
The comparison of the different concocting methods of Test Example Radix Paeoniae Alba.
1, material
Clean Radix Paeoniae Alba sheet is the decoction pieces of root after cutting of the ranunculaceae plant Radix Paeoniae Alba;
The vacuum vapor-phase replacement type medicine processing device, the long prosperous drying equipment company limited in Nanjing;
Multifunction microwave oven, the outstanding full microwave equipment company limited in Nanjing;
Kunming mice, male and female dual-purpose, 18-22g, Shanghai Slac Experimental Animal Co., Ltd..
2, test method
Get same batch of clean Radix Paeoniae Alba sheet 100Kg, be divided into 2 parts, the method for being put down in writing by traditional method and the present invention is respectively concocted, and method is following.
Tradition method (method that reference " Pharmacopoeia of People's Republic of China (2010 editions) " is put down in writing): get clean Radix Paeoniae Alba sheet 50Kg, add the 5Kg yellow wine and mix thoroughly, vexed, to put in the medicine roasting machine, slow fire is fried to little yellow, takes out, and cools.
Microwave vacuum method (with reference to embodiment 3): get clean Radix Paeoniae Alba sheet 50Kg, insert the vacuum vapor-phase replacement type medicine processing device, evacuation reaches-75KPa the relative vacuum degree, keeps the constant adding of vacuum 5Kg yellow wine, recovers normal pressure; Moistening 25min is tiled in above-mentioned material on the pallet, and material thickness is 1.5cm, inserts in the microwave oven and heats; Microwave frequency 2450 ± 50MHz, temperature is 130 ℃ in the stove, heating 10min, during material turning 1 time; During end, take out material, cool, promptly get.
The relatively difference of two kinds of concocting methods aspect following respectively.
2.1 the comparison of different concocting method production times.
2.2 the comparison of the Radix Paeoniae Alba prepared slice quality that distinct methods is concocted
According to the standard of " Pharmacopoeia of People's Republic of China (2010 editions) " defined, compare the quality of the Radix Paeoniae Alba decoction pieces of two kinds of method preparations.
2.3 the comparison of the Radix Paeoniae Alba pharmacological action that different concocting methods are concocted
2.3.1 the influence of Dichlorodiphenyl Acetate inducing mouse writhing response.
2.3.1.1 supply the preparation of reagent thing (Radix Paeoniae Alba water extract) to get Radix Paeoniae Alba 40g, add the 500mL decocting and boil 2 times, each 0.5 hour, collect decoction liquor, filter, be concentrated into 250mL, supply examination.
2.3.1.2 kunming mice is got in grouping and administration, body weight 18-22g, and the male and female dual-purpose is divided into 5 groups at random, wherein: blank group (giving distilled water); The B-CT low dose group (irritate the water extract that stomach gives the Radix Paeoniae Alba of traditional method process of preparing Chinese medicine, dosage 2.4g crude drug/Kg); The B-CT high dose group (irritate the water extract that stomach gives the Radix Paeoniae Alba of traditional method process of preparing Chinese medicine, dosage 4.8g crude drug/Kg); The B-WB low dose group (irritate the water extract that stomach gives the Radix Paeoniae Alba of the microwave vacuum method process of preparing Chinese medicine, dosage 2.4g crude drug/Kg); The B-WB high dose group (irritate the water extract that stomach gives the Radix Paeoniae Alba of the microwave vacuum method process of preparing Chinese medicine, dosage 4.8g crude drug/Kg).30min after the last administration, every Mus lumbar injection 0.6% glacial acetic acid 0.2mL, observe occur in the 15min turn round the body number of times, and calculate the writhing response suppression ratio, suppression ratio thinks that greater than 50% analgesic activity is arranged.
2.3.2 Oleum Tiglii is caused the influence of mice auricle swelling.
2.3.2.1 supply the preparation of reagent thing (Radix Paeoniae Alba water extract): same 2.3.1.1.
2.3.2.2 grouping, administration and method kunming mice, male and female half and half, body weight 18-22g, wherein: blank group (giving distilled water); The B-CT low dose group (irritate the water extract that stomach gives the Radix Paeoniae Alba of traditional method process of preparing Chinese medicine, dosage 2.4g crude drug/Kg); The B-CT high dose group (irritate the water extract that stomach gives the Radix Paeoniae Alba of traditional method process of preparing Chinese medicine, dosage 4.8g crude drug/Kg); The B-WB low dose group (irritate the water extract that stomach gives the Radix Paeoniae Alba of the microwave vacuum method process of preparing Chinese medicine, dosage 2.4g crude drug/Kg); The B-WB high dose group (irritate the water extract that stomach gives the Radix Paeoniae Alba of the microwave vacuum method process of preparing Chinese medicine, dosage 4.8g crude drug/Kg).1h behind the medicine is coated with 2% Fructus Crotonis fluid, 50 μ l with mice left side ear, and 4h post-tensioning neck is put to death, and cuts two ears, sweeps away auricle with diameter 8mm rustless steel blunderbuss, weighs, and the difference of two auricle weight is the swelling degree, compares with matched group, calculates inhibitory rate of intumesce.
2.3.3 date processing and statistical data are represented with mean ± s, analyze with SPSS11.0 software.Note amount data is carried out the significance,statistical analysis with one factor analysis of variance, and enumeration data is used X 2 test.
3, result.
3.1 the comparison of different concocting method production times
Result's (seeing table 1) shows, adopts 45 minutes consuming time (not containing the time that cools) of the present invention's (being the microwave vacuum method) Processing wine Radix Paeoniae Alba, is significantly less than 260 minutes (not the containing the time that cools) of adopting traditional method Processing wine Radix Paeoniae Alba to be consumed.
3.2 the comparison of the Radix Paeoniae Alba prepared slice quality that distinct methods is concocted
Result's (seeing table 2) shows that the Radix Paeoniae Alba that adopts the present invention's process of preparing Chinese medicine all meets the pertinent regulations of " Pharmacopoeia of People's Republic of China (2010 editions) " at the zero difference of concocting with traditional method aspect character, inspection, discriminating, the extractum index; Paeoniflorin content is higher than employing traditional method process of preparing Chinese medicine person in the Radix Paeoniae Alba that employing the inventive method is concocted.
3.3 the comparison of the Radix Paeoniae Alba pharmacological action that distinct methods is concocted
3.3.1 the influence of the Radix Paeoniae Alba Dichlorodiphenyl Acetate inducing mouse writhing response that distinct methods is concocted
Result's (seeing table 3) shows, what each administration group all can significantly reduce the acetic-acid induced mice turns round the body number of times, compares p < 0.05,0.01 with the blank group.Wherein, the B-CT high dose group is compared with the B-WB high dose group, and the B-CT low dose group is compared with the B-WB low dose group, and its difference does not all have statistical significance (p>0.05).Above-mentioned research shows that the Radix Paeoniae Alba analgesic activity that adopts the present invention to concoct is close with the traditional method process of preparing Chinese medicine person of employing.
3.3.2 the Radix Paeoniae Alba that distinct methods is concocted causes the influence of mice auricle swelling to Oleum Tiglii
Result's (seeing table 4) shows that B-WB high dose group, B-WB low dose group, B-CT high dose group all can significantly reduce the degree that Oleum Tiglii causes mice auricle swelling, compare with the blank group (p 0.05,0.01).Wherein, compare with the B-CT high dose group, the mice auricle swelling degree of B-WB high dose group mice obviously alleviates; Its difference has statistical significance (p < 0.05); Above-mentioned research shows that under corresponding dosage, the Radix Paeoniae Alba antiinflammatory action that adopts the present invention to concoct is superior to adopting traditional method process of preparing Chinese medicine person.
In sum, the Radix Paeoniae Alba that adopts the present invention's process of preparing Chinese medicine all meets the pertinent regulations of " Pharmacopoeia of People's Republic of China (2010 editions) " at the zero difference of concocting with traditional method aspect character, inspection, discriminating, the extractum index; Paeoniflorin content is higher than employing traditional method process of preparing Chinese medicine person in the Radix Paeoniae Alba that employing the inventive method is concocted, the Radix Paeoniae Alba analgesic pharmacologically active zero difference that distinct methods is concocted, but adopt the Radix Paeoniae Alba antiinflammatory action of the present invention's process of preparing Chinese medicine to be superior to adopting traditional method process of preparing Chinese medicine person.And adopt the present invention's (being the microwave vacuum method) consuming time shorter, be more suitable for the big production of standardization.
For technical scheme of the present invention better is described, hereinafter will be done further elaboration to its specific embodiment, but the scope that the present invention requires to protect is not limited to following embodiment.
The specific embodiment
Embodiment 1
Get clean Radix Paeoniae Alba sheet 100Kg, insert the vacuum vapor-phase replacement type medicine processing device, evacuation reaches-70KPa the relative vacuum degree, keeps the constant adding of vacuum 10Kg yellow wine, recovers normal pressure; Moistening 30min is tiled in above-mentioned material on the pallet, and material thickness is 1.0cm, inserts in the microwave oven and heats; Microwave frequency 2450 ± 50MHz, temperature is 120 ℃ in the stove, heating 12min, during material turning 2 times; During end, take out material, cool, promptly get.
The Radix Paeoniae Alba quality testing result who makes sees table 5, and the result meets standards of pharmacopoeia.
The result of the test (test method is with reference to Test Example 2.3) that influences of Dichlorodiphenyl Acetate inducing mouse writhing response is seen table 6, shows that the Radix Paeoniae Alba that adopts the present embodiment method to concoct has analgesic activity.
The result of the test (test method is with reference to Test Example 2.3) that influences that Oleum Tiglii is caused mice auricle swelling is seen table 7, shows that the Radix Paeoniae Alba that adopts the present embodiment method to concoct has antiinflammatory action.
Embodiment 2
Get clean Radix Paeoniae Alba sheet 100Kg, insert the vacuum vapor-phase replacement type medicine processing device, evacuation reaches-80KPa the relative vacuum degree, keeps the constant adding of vacuum 50Kg yellow wine, recovers normal pressure; Moistening 20min is tiled in above-mentioned material on the pallet, and material thickness is 2.0cm, inserts in the microwave oven and heats; Microwave frequency 2450 ± 50MHz, temperature is 140 ℃ in the stove, heating 8min, during material turning 1 time; During end, take out material, cool, promptly get.
The Radix Paeoniae Alba quality testing result who makes sees table 8, and the result meets standards of pharmacopoeia.
The result of the test (test method is with reference to Test Example 2.3) that influences of Dichlorodiphenyl Acetate inducing mouse writhing response is seen table 9, shows that the Radix Paeoniae Alba that adopts the present embodiment method to concoct has analgesic activity.
The result of the test (test method is with reference to Test Example 2.3) that influences that Oleum Tiglii is caused mice auricle swelling is seen table 10, shows that the Radix Paeoniae Alba that adopts the present embodiment method to concoct has antiinflammatory action.
Embodiment 3
Get clean Radix Paeoniae Alba sheet 100Kg, insert the vacuum vapor-phase replacement type medicine processing device, evacuation reaches-75KPa the relative vacuum degree, keeps the constant adding of vacuum 10Kg yellow wine, recovers normal pressure; Moistening 25min is tiled in above-mentioned material on the pallet, and material thickness is 1.5cm, inserts in the microwave oven and heats; Microwave frequency 2450 ± 50MHz, temperature is 130 ℃ in the stove, heating 10min, during material turning 1 time; During end, take out material, cool, promptly get.
Claims (6)
1. the concocting method of a Radix Paeoniae Alba is characterized in that described method is made up of the following step: get clean Radix Paeoniae Alba sheet, insert the vacuum vapor-phase replacement type medicine processing device, evacuation make the relative vacuum degree reach-70KPa is to-80KPa; Keep the constant adding yellow wine of vacuum, add the quality of yellow wine and the proportionate relationship of above-mentioned clean Radix Paeoniae Alba tablet quality is 0.1:1, recover normal pressure, moistening 20-30min; Above-mentioned material is tiled on the pallet, and material thickness is 1.0-2.0cm, inserts in the microwave oven and heats, microwave frequency 2450 ± 50MHz; In the stove temperature 120-140 ℃, heating 8-12min, during material turning 1-2 time, during end; Take out material, cool, promptly get.
2. according to the concocting method of right 1 said a kind of Radix Paeoniae Alba, it is characterized in that said relative vacuum degree is-75KPa.
3. according to the concocting method of right 1 said a kind of Radix Paeoniae Alba, the time that it is characterized in that said moistening is 25min.
4. according to the concocting method of right 1 said a kind of Radix Paeoniae Alba, it is characterized in that the said material thickness that is tiled on the pallet is 1.5cm.
5. according to the concocting method of right 1 said a kind of Radix Paeoniae Alba, it is characterized in that temperature is 130 ℃ in the said microwave oven.
6. according to the concocting method of right 1 said a kind of Radix Paeoniae Alba, it is characterized in that said microwave oven heat time heating time is 10min.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201210191530.XA CN102670753B (en) | 2012-06-12 | 2012-06-12 | Method for processing wined white peony root |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201210191530.XA CN102670753B (en) | 2012-06-12 | 2012-06-12 | Method for processing wined white peony root |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN102670753A true CN102670753A (en) | 2012-09-19 |
| CN102670753B CN102670753B (en) | 2014-01-08 |
Family
ID=46803739
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201210191530.XA Active CN102670753B (en) | 2012-06-12 | 2012-06-12 | Method for processing wined white peony root |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN102670753B (en) |
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103083416A (en) * | 2012-11-20 | 2013-05-08 | 亳州市永刚饮片厂有限公司 | Production method of radix paeoniae alba decoction pieces |
| CN107496480A (en) * | 2017-10-13 | 2017-12-22 | 河南省三禾药业有限公司 | The processing procedure and processing ginseng of levelling ginseng |
| CN108685993A (en) * | 2018-08-14 | 2018-10-23 | 安徽弘腾药业有限公司 | A kind of method for processing wined white peony root |
| CN110585274A (en) * | 2019-10-15 | 2019-12-20 | 湖南省中医药研究院 | Processing method of wine-processed white peony roots |
-
2012
- 2012-06-12 CN CN201210191530.XA patent/CN102670753B/en active Active
Non-Patent Citations (2)
| Title |
|---|
| 孟繁智: "《新编中药草图谱大典》", 31 May 2003, 贵州科技出版社 * |
| 许志等: "微波法炮制酒白芍工艺的实验研究", 《时珍国医国药》 * |
Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103083416A (en) * | 2012-11-20 | 2013-05-08 | 亳州市永刚饮片厂有限公司 | Production method of radix paeoniae alba decoction pieces |
| CN107496480A (en) * | 2017-10-13 | 2017-12-22 | 河南省三禾药业有限公司 | The processing procedure and processing ginseng of levelling ginseng |
| CN108685993A (en) * | 2018-08-14 | 2018-10-23 | 安徽弘腾药业有限公司 | A kind of method for processing wined white peony root |
| CN110585274A (en) * | 2019-10-15 | 2019-12-20 | 湖南省中医药研究院 | Processing method of wine-processed white peony roots |
| CN110585274B (en) * | 2019-10-15 | 2021-10-26 | 湖南省中医药研究院 | Processing method of wine-processed white peony roots |
Also Published As
| Publication number | Publication date |
|---|---|
| CN102670753B (en) | 2014-01-08 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN102670733B (en) | Preparation method for vinegar corydalis tuber | |
| CN102670753B (en) | Method for processing wined white peony root | |
| CN101293038B (en) | Gallbladder leaves extract, preparing method, its preparation and uses | |
| WO2013071727A1 (en) | Anti-tumor traditional chinese medical composition | |
| CN102671090A (en) | Preparation method of honeyed stemona tuber | |
| CN103182049A (en) | Preparation method of pharmaceutical composition preparation treating apoplexy sequelae | |
| Li et al. | Adjunctive effect of compound Kushen injection for cancer: an overview of systematic reviews | |
| CN102688295A (en) | Chinese medicine composition for controlling metabolic diseases as well as preparation method and application thereof | |
| CN102397497B (en) | Method for preparing tablets for treating pharyngitis | |
| CN100381434C (en) | Emblic leafflower fruit extract possessing anticancer, antibiotic actions and its manufacturing method of traditional Chinese medicine formulation | |
| CN102670703A (en) | Method for processing honey-fried licorice | |
| CN102688290B (en) | Processing method for wine Salvia miltiorrhiza | |
| CN1704100A (en) | Chinese compound medicinal preparation for treating asthma and method for preparing the same | |
| CN102670734B (en) | Method for processing salted plantain seeds | |
| CN102670676A (en) | Preparation method of wined radix cyathulae | |
| CN102293957B (en) | Chinese medicinal granules for treating related skin disease such as blood heat yang floating disease and preparation method thereof | |
| CN102670678A (en) | Method for preparing salty fennel | |
| CN105727104A (en) | Medicine composition with effects of diminishing inflammation and relieving cough and method for preparing medicine composition | |
| CN102671080A (en) | Processing method for vinegar common burreed rhizome | |
| CN102688278A (en) | Preparation method of vinegar euphorbia kansui | |
| CN104435231A (en) | Method for preparing medicine preparation named Fangfengtongsheng | |
| CN104000875B (en) | Processing method of gelsmium elegans and processed product | |
| CN101095672B (en) | Novel pharmacy use of medicinal composition | |
| CN101579514A (en) | Traditional Chinese medicine for treating infantile susceptible sweating | |
| CN102397453B (en) | Method for preparing tablets for treating rhinitis |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| C41 | Transfer of patent application or patent right or utility model | ||
| CB03 | Change of inventor or designer information |
Inventor after: Liu Zhifeng Inventor before: Wang Feng Inventor before: Wang Lin Inventor before: Zhang Facheng |
|
| COR | Change of bibliographic data | ||
| TR01 | Transfer of patent right |
Effective date of registration: 20161010 Address after: Tianhe District Tong East Road Guangzhou city Guangdong province 510665 B-101 No. 5, room B-118 Patentee after: GUANGDONG GAOHANG INTELLECTUAL PROPERTY OPERATION Co.,Ltd. Address before: 215011 Jiangsu high tech Zone Suzhou City Binhe Road, No. 1326 Patentee before: Suzhou Paiteng Biological Medical Technology Co.,Ltd. Effective date of registration: 20161010 Address after: 515000 No. 1, Qishan Industrial Zone, Jinping District, Guangdong, Shantou Patentee after: SHANTOU YUEDONG PHARMACEUTICAL CO.,LTD. Address before: Tianhe District Tong East Road Guangzhou city Guangdong province 510665 B-101 No. 5, room B-118 Patentee before: GUANGDONG GAOHANG INTELLECTUAL PROPERTY OPERATION Co.,Ltd. |
|
| PE01 | Entry into force of the registration of the contract for pledge of patent right |
Denomination of invention: Method for processing wined white peony root Effective date of registration: 20181213 Granted publication date: 20140108 Pledgee: Shantou SME financing Company limited by guarantee Pledgor: SHANTOU YUEDONG PHARMACEUTICAL CO.,LTD. Registration number: 2018990001198 |
|
| PE01 | Entry into force of the registration of the contract for pledge of patent right | ||
| PC01 | Cancellation of the registration of the contract for pledge of patent right |
Date of cancellation: 20191126 Granted publication date: 20140108 Pledgee: Shantou SME financing Company limited by guarantee Pledgor: SHANTOU YUEDONG PHARMACEUTICAL CO.,LTD. Registration number: 2018990001198 |
|
| PC01 | Cancellation of the registration of the contract for pledge of patent right | ||
| PE01 | Entry into force of the registration of the contract for pledge of patent right |
Denomination of invention: A processing method of white peony wine Effective date of registration: 20230321 Granted publication date: 20140108 Pledgee: Bank of China Limited by Share Ltd. Shantou branch Pledgor: SHANTOU YUEDONG PHARMACEUTICAL CO.,LTD. Registration number: Y2023980035598 |
|
| PE01 | Entry into force of the registration of the contract for pledge of patent right |