CN102657525A - Nondestructive detection system and method of cardiac function - Google Patents
Nondestructive detection system and method of cardiac function Download PDFInfo
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Abstract
The invention provides a nondestructive detection system and a nondestructive detection method of a cardiac function. The nondestructive detection system of the cardiac function mainly comprises a central control computer, and an electrocardiography signal acquisition module, a heart sound signal acquisition module and a thoracic impedance acquisition module which are in data communication with the central control computer to acquire an electrocardiography signal, a heart sound signal and a thoracic impedance signal respectively, wherein related physiological and pathological characteristic parameters are obtained from the electrocardiography signal, the heart sound signal and the thoracic impedance signal through comprehensive processing of the central control computer, and further related index parameters of the cardiac function are obtained and displayed in real time. The nondestructive detection system and the nondestructive detection method of the cardiac function have higher detection accuracy; the clinical applicability of the nondestructive detection system and the nondestructive detection method is improved; the technical blank that effective nondestructive detection related equipment of the cardiac function is not available yet at present in China; rich operation and remote functions can be realized by combining the conventional computer technology and network technology, and the nondestructive detection system and the nondestructive detection method have excellent application prospect.
Description
Technical field
The present invention relates to biomedical engineering technology and technical field of information processing, particularly a kind of cardiac function noinvasive detection system and method.
Background technology
The hemodynamic parameter monitoring that reflects power aroused in interest has been used for for many years clinical.The monitoring of hemodynamic parameter; Much extremely valuable parameter information can be provided; For example cardiac pumping function index parameter, cardiac systolic function index parameter, index of cardiovascular performance parameter etc., the index parameter that these cardiac function are relevant all has the important clinical meaning to medical treatment and scientific research.Along with clinical medical development, various hemodynamics detection methods are arisen at the historic moment.At present, the method for hemodynamic examination mainly is divided into two big types: the first kind is for having wound detection method, i.e. traditional detection method; Mainly contain Swan-Ganz tremie method, pulse and indicate continuous cardiac output technology; But, not only bring the health wound, and the expensive that has wound to detect to the patient owing to there is the wound detection method wound Data Detection to be arranged to the patient; Operating technology to the testing staff requires also than higher; Also need the professional to explain the Clinical detection data, and the expense that hospital collects from the patient often has wound to detect cost far below cardiac function there, so hematodinamics there is the clinical practice of wound detection method to be difficult to popularize; Second type is the noinvasive detection method, comprises carbon dioxide heart stroke algoscopy, doppler ultrasound and breast impedance method, and the ICG parameter of its mesothorax impedance method has good using value to patients such as heart failure, hypertension, dyspnea; Can let the doctor more accurately diagnose, control risk; Select best clinical treatment, improve patients'prognosis, and can not bring traumatic pain to the patient; It is also relatively low to detect cost; Particularly the out of use occasion of wound method is being arranged, like critical patient, light patient, conduit taboo patient and healthy subjects, the breast impedance method is a kind of ideal detection method.Yet the domestic present checkout equipment that detects according to breast impedance method realization hematodinamics noinvasive in clinical practice is also seldom traced it to its cause, and is that the Clinical detection precision of this method is not also accepted by numerous doctors.Therefore, be necessary the cardiac function noinvasive checkout equipment based on the breast impedance method is further furtherd investigate, improve its clinical practice precision, realize the extensive use of cardiac function noinvasive checkout equipment.
Summary of the invention
Above-mentioned deficiency to the prior art existence; The object of the present invention is to provide a kind of cardiac function noinvasive detection system; With the detection cost that reduces cardiac function index of correlation parameter, the clinical applicability that improves the detection of cardiac function noinvasive; Hemodynamic parameter has wound to detect the problem of cost height, clinical applicability difference in the solution prior art, remedies the domestic technological vacancy that does not occur effective cardiac function noinvasive detection relevant device at present as yet.
For realizing above-mentioned purpose, the present invention has adopted following technological means:
A kind of cardiac function noinvasive detection system, control computer and the ecg signal acquiring module that is connected with middle control computer data communication, cardiechema signals acquisition module and breast impedance collection module in comprising;
Said ecg signal acquiring module is used to gather the electrocardiosignal of detected object;
Said cardiechema signals acquisition module is used to gather the cardiechema signals of detected object;
Said breast impedance collection module is used to gather the thoracic impedance signal of detected object;
Electrocardiosignal analytical model, analysis of PCG Signal model, thoracic impedance signal analytical model and parameters of left ventricular function function model have been pre-seted in the control computer in said; Said ECG Signal Analysis model is used for the electrocardiosignal of detected object is analyzed; Export corresponding electrocardiosignal characteristic parameter, said electrocardiosignal characteristic parameter comprises position that P point in the electrocardiosignal, Q point, R point, S point and T are ordered and heart rate, P wave width, QRS complex wave width, T wave width, RR interval, PR interval, ST interval and QT interval; Said analysis of PCG Signal model is used for the cardiechema signals of detected object is analyzed, and exports corresponding cardiechema signals characteristic parameter, and said cardiechema signals characteristic parameter comprises the width and the amplitude of first heart sound, second heart sound, third heart sound and fourth heart sound; Said thoracic impedance signal analytical model is used for the thoracic impedance signal of detected object is analyzed, and exports corresponding thoracic impedance signal characteristic parameter, and said thoracic impedance signal characteristic parameter comprises the position that A point in the thoracic impedance signal, B point, C point, X point and O are ordered; Said parameters of left ventricular function function model is used for obtaining according to said electrocardiosignal characteristic parameter, cardiechema signals characteristic parameter and the analysis of thoracic impedance signal characteristic parameter the index parameter of corresponding cardiac pumping function, cardiac systolic function and cardiovascular function; Electrocardiosignal, cardiechema signals and the thoracic impedance signal of control computer can be through communicating with connection in said ecg signal acquiring module, cardiechema signals acquisition module and breast impedance collection module synchronous acquisition detected object; With electrocardiosignal, cardiechema signals and the thoracic impedance signal of synchronous acquisition respectively as the input of ECG Signal Analysis model, analysis of PCG Signal model and thoracic impedance signal analytical model; Again with the input of electrocardiosignal characteristic parameter, cardiechema signals characteristic parameter and the thoracic impedance signal characteristic parameter of ECG Signal Analysis model, analysis of PCG Signal model and the output of thoracic impedance signal analytical model as the parameters of left ventricular function function model; Obtain the index parameter of cardiac pumping function, cardiac systolic function and the cardiovascular function of detected object, and show in real time.
In the above-mentioned cardiac function noinvasive detection system; But as a kind of selection scheme, said breast impedance collection module mainly is made up of control circuit, exciting current generation circuit, activation fragment buffer circuit, four exciting electrodes, four acquisition electrodes, capture segment buffer circuit and amplifying and conditioning circuit; Said control circuit is electrically connected with exciting current generation circuit; And carry out data communication with middle control computer and be connected; Control circuit is used for receiving the breast impedance collection control signal from control computer, and produces stimulating current according to breast impedance collection control signal control exciting current generation circuit; Said exciting current generation circuit also is electrically connected with four exciting electrodes through the activation fragment buffer circuit, is used under the control of control circuit, producing stimulating current and acts on human body through four exciting electrodes; Two acquisition electrodes in said four acquisition electrodes are used to be arranged on human chest xiphoid-process place, and two acquisition electrodes are used to be arranged on human body neck root both sides in addition, to gather the voltage signal after stimulating current acts on human body; Two exciting electrodes in said four exciting electrodes are used to be separately positioned on the 3cm place, below that two acquisition electrodes in human chest xiphoid-process place are provided with the position, and two exciting electrodes are used to be separately positioned on the 3cm place, top that two acquisition electrodes in human body neck root both sides are provided with the position in addition; Amplifying and conditioning circuit is electrically connected with four acquisition electrodes through the capture segment buffer circuit; And carry out data communication with middle control computer and be connected, amplifying and conditioning circuit can be amplified the voltage signal of four acquisition electrode collections the back conversion process and is thoracic impedance signal and export middle control computer to.
In the above-mentioned cardiac function noinvasive detection system; As further improvement project; Also preset sample individual information data base and the individual penalty function model of being equipped with in the control computer in said; Said individual information data base is used to store the individual information of the detected object of typing, and said individual penalty function model is used to write down the Function Mapping relation of individual information of offset and the detected object of cardiac pumping function index parameter, cardiac systolic function index parameter and index of cardiovascular performance parameter; In control computer can the individual information of detected object be obtained the offset of cardiac pumping function index parameter, cardiac systolic function index parameter and index of cardiovascular performance parameter as the input of individual penalty function; Utilize said offset respectively cardiac pumping function index parameter, cardiac systolic function index parameter and the index of cardiovascular performance parameter of corresponding detected object to be compensated and corrected; The index parameter of the cardiac pumping function of the detected object that obtains revising, cardiac systolic function and cardiovascular function, and show in real time.
Correspondingly, the present invention also provides a kind of cardiac function noinvasive detection method, and the present invention has adopted following technological means for this reason:
A kind of cardiac function noinvasive detection method specifically may further comprise the steps:
A) ECG Signal Analysis model, analysis of PCG Signal model, thoracic impedance signal analytical model and parameters of left ventricular function function model are set in advance in middle control computer; Said ECG Signal Analysis model is used for the electrocardiosignal of detected object is analyzed; Export corresponding electrocardiosignal characteristic parameter, said electrocardiosignal characteristic parameter comprises position that P point in the electrocardiosignal, Q point, R point, S point and T are ordered and heart rate, P wave width, QRS complex wave width, T wave width, RR interval, PR interval, ST interval and QT interval; Said analysis of PCG Signal model is used for the cardiechema signals of detected object is analyzed, and exports corresponding cardiechema signals characteristic parameter, and said cardiechema signals characteristic parameter comprises the width and the amplitude of first heart sound, second heart sound, third heart sound and fourth heart sound; Said thoracic impedance signal analytical model is used for the thoracic impedance signal of detected object is analyzed, and exports corresponding thoracic impedance signal characteristic parameter, and said thoracic impedance signal characteristic parameter comprises the position that A point in the thoracic impedance signal, B point, C point, X point and O are ordered; Said parameters of left ventricular function function model is used for obtaining according to said electrocardiosignal characteristic parameter, cardiechema signals characteristic parameter and the analysis of thoracic impedance signal characteristic parameter the index parameter of corresponding cardiac pumping function, cardiac systolic function and cardiovascular function;
B) electrocardiosignal, cardiechema signals and the thoracic impedance signal through the ecg signal acquiring module, cardiechema signals acquisition module and the breast impedance collection module synchronous acquisition detected object that are connected with middle control computer data communication and transfer to middle control computer;
C) in control computer with electrocardiosignal, cardiechema signals and the thoracic impedance signal of synchronous acquisition respectively as the input of ECG Signal Analysis model, analysis of PCG Signal model and thoracic impedance signal analytical model; Again with the input of electrocardiosignal characteristic parameter, cardiechema signals characteristic parameter and the thoracic impedance signal characteristic parameter of ECG Signal Analysis model, analysis of PCG Signal model and the output of thoracic impedance signal analytical model as the parameters of left ventricular function function model; Obtain the index parameter of cardiac pumping function, cardiac systolic function and the cardiovascular function of detected object, and show in real time.
In the above-mentioned cardiac function noinvasive detection method; As further improvement project; In said steps A) in; In middle control computer, also be provided with sample individual information data base and individual penalty function model in advance; Said individual information data base is used to store the individual information of the detected object of typing, and said individual penalty function model is used to write down the Function Mapping relation of individual information of offset and the detected object of cardiac pumping function index parameter, cardiac systolic function index parameter and index of cardiovascular performance parameter; At said step C) in; After middle control computer is resolved the index parameter of the cardiac pumping function, cardiac systolic function and the cardiovascular function that obtain detected object; Also with the individual information of detected object as the input of individual penalty function and obtain the offset of cardiac pumping function index parameter, cardiac systolic function index parameter and index of cardiovascular performance parameter; Utilize said offset respectively cardiac pumping function index parameter, cardiac systolic function index parameter and the index of cardiovascular performance parameter of corresponding detected object to be compensated and corrected; The index parameter of the cardiac pumping function of the detected object that obtains revising, cardiac systolic function and cardiovascular function, and show in real time.
Compare prior art, the present invention has following beneficial effect:
1, cardiac function noinvasive detection system of the present invention is utilized multiple signal parameter acquisition module; Realize the synchronous acquisition of different physiology, pathological signals; On existing sophisticated breast impedance method basis, improved the cardiac function noinvasive and detected comprehensive and reasonability, thereby made cardiac function noinvasive detection system of the present invention have the higher detection precision; Improve its clinical applicability, remedied the domestic technological vacancy that effective cardiac function noinvasive detects relevant device that do not occur as yet at present.
2, cardiac function noinvasive detection system of the present invention can adopt the computing technique of technology maturation and circuit module technique construction to form, and is simple in structure, cost is low, structure is convenient, greatly reduces it and detects cost and clinical practice difficulty.
3, cardiac function noinvasive detection system of the present invention is its processing core of cardiac function testing result with the computer; Can realize the storage of detected object data; Functions such as the demonstration of cardiac function testing result, printing; And can make up data base management system (for example HIS system) and manage, can also perhaps realize the remote detection and the consultation of doctors, have good application prospects through networking and hospital information system shared data.
4, cardiac function noinvasive detection method of the present invention has adopted the analytical model based on multiparameter to obtain multiple cardiac function index of correlation parameter; The cardiac function testing result that makes noinvasive obtain reflects the situation of change of cardiac function with multiple physiology, pathological signals parameter more comprehensively, has avoided the unsettled defective of single parameter cardiac function noinvasive detection method testing result.
5, as further improvement project; Cardiac function noinvasive detection method of the present invention is also introduced individual penalty function model; Obtain the offset of cardiac function index of correlation parameter with individual information through detected object; Cardiac function testing result to detected object compensates and corrects, and has further remedied the influence of individual variation to the cardiac function testing result, makes this method have better clinical applicability and robustness.
Description of drawings
Fig. 1 is the structured flowchart of cardiac function noinvasive detection system of the present invention;
Fig. 2 is the FB(flow block) of cardiac function noinvasive detection method of the present invention;
Fig. 3 is the FB(flow block) of cardiac function noinvasive detection method improvement project of the present invention.
The specific embodiment
Below in conjunction with accompanying drawing and embodiment technical scheme of the present invention is described further:
As shown in Figure 1; Cardiac function noinvasive detection system of the present invention mainly is made up of middle control computer and the multiple signal parameter acquisition module that is connected with middle control computer data communication, utilizes these signal parameter acquisition modules to realize the synchronous acquisition of different physiology, pathological signals; These signal parameter acquisition modules comprise ecg signal acquiring module, cardiechema signals acquisition module and breast impedance collection module; Be used for gathering respectively electrocardiosignal, cardiechema signals and thoracic impedance signal and transfer to control computer; Integrated treatment through middle control calculating; Obtain relevant physiology, pathological characters parameter by electrocardiosignal, cardiechema signals and thoracic impedance signal, and then obtain the relevant index parameter of cardiac function, and show in real time.
The ecg signal acquiring module mainly is made up of three lead electrocardioelectrode and electrocardiosignal amplifying circuits, is used to gather electrocardiosignal; Its circuit constitutes with electrocardiosignal detector signals collecting circuit structure partly is basic identical on the market, belongs to the circuit structure of technology maturation.
The cardiechema signals acquisition module mainly is made up of heart sound transducer and cardiechema signals amplifying circuit, is used to gather cardiechema signals.Used heart sound transducer and cardiechema signals amplifying circuit in the practical application can be to use sophisticated heart sound transducer product and signal amplification circuit module.
Breast impedance collection module adopts the self-control circuit to realize, is used to gather patient's thoracic impedance signal; Breast impedance collection module mainly is made up of control circuit, exciting current generation circuit, activation fragment buffer circuit, four exciting electrodes, four acquisition electrodes, capture segment buffer circuit and amplifying and conditioning circuit; Control circuit is electrically connected with exciting current generation circuit; And carry out data communication with middle control computer and be connected; Control circuit is used for receiving the breast impedance collection control signal from control computer; And produce stimulating current according to breast impedance collection control signal control exciting current generation circuit, stimulating current be generally 40KHz ~ 120KHz, amplitude less than/equal the weak current of 4mA; Exciting current generation circuit also is electrically connected with four exciting electrodes through the activation fragment buffer circuit, is used under the control of control circuit, producing stimulating current and acts on human body through four exciting electrodes; Two acquisition electrodes in four acquisition electrodes are used to be arranged on human chest xiphoid-process place, and two acquisition electrodes are used to be arranged on human body neck root both sides in addition, to gather the voltage signal after stimulating current acts on human body; Two exciting electrodes in said four exciting electrodes are used to be separately positioned on the 3cm place, below that two acquisition electrodes in human chest xiphoid-process place are provided with the position, and two exciting electrodes are used to be separately positioned on the 3cm place, top that two acquisition electrodes in human body neck root both sides are provided with the position in addition; Amplifying and conditioning circuit is electrically connected with four acquisition electrodes through the capture segment buffer circuit; And carry out data communication with middle control computer and be connected, amplifying and conditioning circuit can be amplified the voltage signal of four acquisition electrode collections the back conversion process and is thoracic impedance signal and export middle control computer to.
Electrocardiosignal analytical model, analysis of PCG Signal model, thoracic impedance signal analytical model and parameters of left ventricular function function model have been pre-seted in the middle control computer; The ECG Signal Analysis model is used for the electrocardiosignal of detected object is analyzed; Export corresponding electrocardiosignal characteristic parameter, said electrocardiosignal characteristic parameter comprises position that P point in the electrocardiosignal, Q point, R point, S point and T are ordered and heart rate, P wave width, QRS complex wave width, T wave width, RR interval, PR interval, ST interval and QT interval; The analysis of PCG Signal model is used for the cardiechema signals of detected object is analyzed, and exports corresponding cardiechema signals characteristic parameter, and said cardiechema signals characteristic parameter comprises the width and the amplitude of first heart sound, second heart sound, third heart sound and fourth heart sound; The thoracic impedance signal analytical model is used for the thoracic impedance signal of detected object is analyzed, and exports corresponding thoracic impedance signal characteristic parameter, and said thoracic impedance signal characteristic parameter comprises the position that A point in the thoracic impedance signal, B point, C point, X point and O are ordered; When thoracic impedance signal is analyzed; Can also be with the point as a reference of Q point position in the electrocardiosignal; Assist location is carried out in position in conjunction with the amplitude maximum of first heart sound in the cardiechema signals and second heart sound is ordered to A point, B point, C point, X point and O in the thoracic impedance signal, the location positioning degree of accuracy of ordering with further raising A point, B point, C point, X point and O; Above-mentioned these electrocardiosignal characteristic parameters, cardiechema signals characteristic parameter, thoracic impedance signal characteristic parameter all have clear and definite definition in the pertinent literature of medical domain and teaching material, this paper no longer carries out repetition of explanation to its concrete medical science implication; The parameters of left ventricular function function model is used for obtaining according to said electrocardiosignal characteristic parameter, cardiechema signals characteristic parameter and the analysis of thoracic impedance signal characteristic parameter the index parameter of corresponding cardiac pumping function, cardiac systolic function and cardiovascular function; In control computer can be through communicating with connection electrocardiosignal, cardiechema signals and the thoracic impedance signal of ecg signal acquiring module, cardiechema signals acquisition module and breast impedance collection module synchronous acquisition detected object; With electrocardiosignal, cardiechema signals and the thoracic impedance signal of synchronous acquisition respectively as the input of ECG Signal Analysis model, analysis of PCG Signal model and thoracic impedance signal analytical model; Again with the input of electrocardiosignal characteristic parameter, cardiechema signals characteristic parameter and the thoracic impedance signal characteristic parameter of ECG Signal Analysis model, analysis of PCG Signal model and the output of thoracic impedance signal analytical model as the parameters of left ventricular function function model; Obtain the index parameter of cardiac pumping function, cardiac systolic function and the cardiovascular function of detected object, and show in real time.In the circuit design of control computer can adopt the circuit design scheme of existing personal computer fully, if control cost, also can adopt arm processor, dsp processor etc. to be the embedded design scheme of core; The multi-channel data acquisition card can be installed as the multi-channel data interface on the middle control computer, so that the multiple signal data of synchronous acquisition.
This shows that cardiac function noinvasive detection system of the present invention can adopt the computing technique of technology maturation and circuit module technique construction to form, simple in structure, cost is low, structure is convenient, greatly reduce it and detect cost and clinical practice difficulty.Cardiac function noinvasive detection system of the present invention is utilized multiple signal parameter acquisition module; Realize the synchronous acquisition of different physiology, pathological signals; On existing sophisticated breast impedance method basis, improved the cardiac function noinvasive and detected comprehensive and reasonability, thereby made cardiac function noinvasive detection system of the present invention have the higher detection precision; Improve its clinical applicability, remedied the domestic technological vacancy that effective cardiac function noinvasive detects relevant device that do not occur as yet at present; Moreover; Cardiac function noinvasive detection system of the present invention is its processing core of cardiac function testing result with the computer; And combining existing computer technology and network technology, the further Programming Design through to system can realize the storage of detected object data; Functions such as the demonstration of cardiac function testing result, printing; And can make up data base management system (HIS system) and manage, can also perhaps realize the remote detection and the consultation of doctors, have good application prospects through networking and hospital information system shared data.
Adopt above-mentioned cardiac function noinvasive detection system, can realize cardiac function noinvasive detection method of the present invention, its flow process is as shown in Figure 2, and concrete steps are following:
A) ECG Signal Analysis model, analysis of PCG Signal model, thoracic impedance signal analytical model and parameters of left ventricular function function model are set in advance in middle control computer; Said ECG Signal Analysis model is used for the electrocardiosignal of detected object is analyzed; Export corresponding electrocardiosignal characteristic parameter, said electrocardiosignal characteristic parameter comprises position that P point in the electrocardiosignal, Q point, R point, S point and T are ordered and heart rate, P wave width, QRS complex wave width, T wave width, RR interval, PR interval, ST interval and QT interval; Said analysis of PCG Signal model is used for the cardiechema signals of detected object is analyzed, and exports corresponding cardiechema signals characteristic parameter, and said cardiechema signals characteristic parameter comprises the width and the amplitude of first heart sound, second heart sound, third heart sound and fourth heart sound; Said thoracic impedance signal analytical model is used for the thoracic impedance signal of detected object is analyzed, and exports corresponding thoracic impedance signal characteristic parameter, and said thoracic impedance signal characteristic parameter comprises the position that A point in the thoracic impedance signal, B point, C point, X point and O are ordered; Said parameters of left ventricular function function model is used for obtaining according to said electrocardiosignal characteristic parameter, cardiechema signals characteristic parameter and the analysis of thoracic impedance signal characteristic parameter the index parameter of corresponding cardiac pumping function, cardiac systolic function and cardiovascular function;
B) electrocardiosignal, cardiechema signals and the thoracic impedance signal through the ecg signal acquiring module, cardiechema signals acquisition module and the breast impedance collection module synchronous acquisition detected object that are connected with middle control computer data communication and transfer to middle control computer;
C) in control computer with electrocardiosignal, cardiechema signals and the thoracic impedance signal of synchronous acquisition respectively as the input of ECG Signal Analysis model, analysis of PCG Signal model and thoracic impedance signal analytical model; Again with the input of electrocardiosignal characteristic parameter, cardiechema signals characteristic parameter and the thoracic impedance signal characteristic parameter of ECG Signal Analysis model, analysis of PCG Signal model and the output of thoracic impedance signal analytical model as the parameters of left ventricular function function model; Obtain the index parameter of cardiac pumping function, cardiac systolic function and the cardiovascular function of detected object, and show in real time.
In the above-mentioned cardiac function noinvasive detection method; The processing capacity of middle control computer can utilize Visual C++6.0 programming language to realize; Processing capacity software operation work on operating system platforms such as Windows, Linux that programming obtains is to adapt to different client's needs.In the function treatment software of middle control computer, can realize synchronous recording and unified management specially to these physiology, synchrodata logging modle of pathological signals structure of above-mentioned synchronous acquisition to these physiology, pathological signals; Simultaneously, can be specially to cardiac function testing result display interface of demonstration structure of cardiac function index of correlation parameter detecting result, cardiac function index of correlation parameter detecting result and coherent signal characteristic parameter that detection is obtained show.ECG Signal Analysis model in the system, analysis of PCG Signal model and thoracic impedance signal analytical model; Be used for analyzing respectively and draw electrocardiosignal characteristic parameter, cardiechema signals characteristic parameter and thoracic impedance signal characteristic parameter; Therefore can utilize existing Digital Signal Analysis recognition technology and mathematical modeling technology to set up according to the data characteristics of these characteristic parameters in signal separately.And for the parameters of left ventricular function function model in the system; The patient crowd that then can select to suit is as the training sample object; From pathology and biomechanics angle; Utilize ecg signal acquiring module, cardiechema signals acquisition module and breast impedance collection module to gather electrocardiosignal, cardiechema signals and the thoracic impedance signal of training sample object; Utilize the cardiac function index of correlation parameter detecting result that wound cardiac monitoring device synchronous acquisition training sample object reality is arranged who is connected with middle control computer data communication simultaneously; Because electrocardiosignal characteristic parameter, cardiechema signals characteristic parameter and thoracic impedance signal characteristic parameter and cardiac function have closer getting in touch; Therefore, through data mining with analyze identification, extract the training sample object of different syndromes electrocardiosignal characteristic parameter, cardiechema signals characteristic parameter and thoracic impedance signal characteristic parameter variation respectively and the dependency relation between the variation of cardiac function index of correlation parameter; Can confirm corresponding cardiac function index of correlation parameter according to characteristic parameter, obtain the parameters of left ventricular function function model through mathematical modeling again; Training is set up in the process of parameters of left ventricular function function model; The cardiac function index of correlation parameter detecting result who why selects for use the wound cardiac monitoring device to gather the training sample object; Be because than existing non-invasive cardiac function detection method; The existing real changes of cardiac function situation that has the wound cardiac monitoring device more can detect the training sample object exactly avoids the deviation of data in the modeling to bring irremediable computing deviation to system, with the accuracy that guarantees that the cardiac function noinvasive detects.After obtaining ECG Signal Analysis model, analysis of PCG Signal model, thoracic impedance signal analytical model and parameters of left ventricular function function model; Patient for cardiac function to be measured; Then need not to have again the wound cardiac function to detect; But through detecting patient's electrocardiosignal, cardiechema signals and thoracic impedance signal; Carry out multiparameter, multi-faceted comprehensive calculation process by ECG Signal Analysis model, analysis of PCG Signal model, thoracic impedance signal analytical model and parameters of left ventricular function function model, promptly arrive corresponding cardiac function index of correlation parameter detecting result; Because the detection of electrocardiosignal, cardiechema signals and thoracic impedance signal all is noninvasive; Thereby realized the noinvasive of cardiac function is detected; Simultaneously; Because this detection method has been taken all factors into consideration multiple physiology, the pathological signals parameter that causes changes of cardiac function, thereby cardiac function noinvasive detection method of the present invention has had higher Clinical detection precision.
As further improvement project; In the processing capacity software of middle control computer; Also preset sample individual information data base and the individual penalty function model of being equipped with; The individual information data base is used to store the individual information of the detected object of typing, and individual penalty function model is used to write down the Function Mapping relation of individual information of offset and the detected object of cardiac pumping function index parameter, cardiac systolic function index parameter and index of cardiovascular performance parameter; The cardiac function noinvasive detection method flow process of this improvement project is as shown in Figure 3; Detect steps A at aforementioned cardiac function noinvasive) ~ C) basis on; In said steps A) in, in middle control computer, also be provided with sample individual information data base and individual penalty function model in advance; At said step C) in; After middle control computer is resolved the index parameter of the cardiac pumping function, cardiac systolic function and the cardiovascular function that obtain detected object; Also with the individual information of detected object as the input of individual penalty function and obtain the offset of cardiac pumping function index parameter, cardiac systolic function index parameter and index of cardiovascular performance parameter; Utilize said offset respectively cardiac pumping function index parameter, cardiac systolic function index parameter and the index of cardiovascular performance parameter of corresponding detected object to be compensated and corrected; The index parameter of the cardiac pumping function of the detected object that obtains revising, cardiac systolic function and cardiovascular function, and show in real time.The individual information of detected object can comprise one or more information in the information such as the sex, age, height, body weight, clinical disease, physical signs of detected object, can confirm according to the actual clinical needs.Individual penalty function model can be by secular Clinical detection, diagnostic data; By virtue of experience analyze the influence that Different Individual information changes cardiac function index of correlation parameter and obtain; In order to further to remedy the influence of individual variation, make this cardiac function noinvasive detection method have better clinical applicability and robustness to the cardiac function testing result.
Explanation is at last; Above embodiment is only unrestricted in order to technical scheme of the present invention to be described; Although with reference to preferred embodiment the present invention is specified, those of ordinary skill in the art should be appreciated that and can make amendment or be equal to replacement technical scheme of the present invention; And not breaking away from the aim and the scope of technical scheme of the present invention, it all should be encompassed in the middle of the claim scope of the present invention.
Claims (5)
1. a cardiac function noinvasive detection system is characterized in that, control computer and the ecg signal acquiring module that is connected with middle control computer data communication, cardiechema signals acquisition module and breast impedance collection module in comprising;
Said ecg signal acquiring module is used to gather the electrocardiosignal of detected object;
Said cardiechema signals acquisition module is used to gather the cardiechema signals of detected object;
Said breast impedance collection module is used to gather the thoracic impedance signal of detected object;
Electrocardiosignal analytical model, analysis of PCG Signal model, thoracic impedance signal analytical model and parameters of left ventricular function function model have been pre-seted in the control computer in said; Said ECG Signal Analysis model is used for the electrocardiosignal of detected object is analyzed; Export corresponding electrocardiosignal characteristic parameter, said electrocardiosignal characteristic parameter comprises position that P point in the electrocardiosignal, Q point, R point, S point and T are ordered and heart rate, P wave width, QRS complex wave width, T wave width, RR interval, PR interval, ST interval and QT interval; Said analysis of PCG Signal model is used for the cardiechema signals of detected object is analyzed, and exports corresponding cardiechema signals characteristic parameter, and said cardiechema signals characteristic parameter comprises the width and the amplitude of first heart sound, second heart sound, third heart sound and fourth heart sound; Said thoracic impedance signal analytical model is used for the thoracic impedance signal of detected object is analyzed, and exports corresponding thoracic impedance signal characteristic parameter, and said thoracic impedance signal characteristic parameter comprises the position that A point in the thoracic impedance signal, B point, C point, X point and O are ordered; Said parameters of left ventricular function function model is used for obtaining according to said electrocardiosignal characteristic parameter, cardiechema signals characteristic parameter and the analysis of thoracic impedance signal characteristic parameter the index parameter of corresponding cardiac pumping function, cardiac systolic function and cardiovascular function; Electrocardiosignal, cardiechema signals and the thoracic impedance signal of control computer can be through communicating with connection in said ecg signal acquiring module, cardiechema signals acquisition module and breast impedance collection module synchronous acquisition detected object; With electrocardiosignal, cardiechema signals and the thoracic impedance signal of synchronous acquisition respectively as the input of ECG Signal Analysis model, analysis of PCG Signal model and thoracic impedance signal analytical model; Again with the input of electrocardiosignal characteristic parameter, cardiechema signals characteristic parameter and the thoracic impedance signal characteristic parameter of ECG Signal Analysis model, analysis of PCG Signal model and the output of thoracic impedance signal analytical model as the parameters of left ventricular function function model; Obtain the index parameter of cardiac pumping function, cardiac systolic function and the cardiovascular function of detected object, and show in real time.
2. cardiac function noinvasive detection system according to claim 1; It is characterized in that said breast impedance collection module mainly is made up of control circuit, exciting current generation circuit, activation fragment buffer circuit, four exciting electrodes, four acquisition electrodes, capture segment buffer circuit and amplifying and conditioning circuit; Said control circuit is electrically connected with exciting current generation circuit; And carry out data communication with middle control computer and be connected; Control circuit is used for receiving the breast impedance collection control signal from control computer, and produces stimulating current according to breast impedance collection control signal control exciting current generation circuit; Said exciting current generation circuit also is electrically connected with four exciting electrodes through the activation fragment buffer circuit, is used under the control of control circuit, producing stimulating current and acts on human body through four exciting electrodes; Two acquisition electrodes in said four acquisition electrodes are used to be arranged on human chest xiphoid-process place, and two acquisition electrodes are used to be arranged on human body neck root both sides in addition, to gather the voltage signal after stimulating current acts on human body; Two exciting electrodes in said four exciting electrodes are used to be separately positioned on the 3cm place, below that two acquisition electrodes in human chest xiphoid-process place are provided with the position, and two exciting electrodes are used to be separately positioned on the 3cm place, top that two acquisition electrodes in human body neck root both sides are provided with the position in addition; Amplifying and conditioning circuit is electrically connected with four acquisition electrodes through the capture segment buffer circuit; And carry out data communication with middle control computer and be connected, amplifying and conditioning circuit can be amplified the voltage signal of four acquisition electrode collections the back conversion process and is thoracic impedance signal and export middle control computer to.
3. cardiac function noinvasive detection system according to claim 1; It is characterized in that; Also preset sample individual information data base and the individual penalty function model of being equipped with in the control computer in said; Said individual information data base is used to store the individual information of the detected object of typing, and said individual penalty function model is used to write down the Function Mapping relation of individual information of offset and the detected object of cardiac pumping function index parameter, cardiac systolic function index parameter and index of cardiovascular performance parameter; In control computer can the individual information of detected object be obtained the offset of cardiac pumping function index parameter, cardiac systolic function index parameter and index of cardiovascular performance parameter as the input of individual penalty function; Utilize said offset respectively cardiac pumping function index parameter, cardiac systolic function index parameter and the index of cardiovascular performance parameter of corresponding detected object to be compensated and corrected; The index parameter of the cardiac pumping function of the detected object that obtains revising, cardiac systolic function and cardiovascular function, and show in real time.
4. a cardiac function noinvasive detection method is characterized in that, specifically may further comprise the steps:
A) ECG Signal Analysis model, analysis of PCG Signal model, thoracic impedance signal analytical model and parameters of left ventricular function function model are set in advance in middle control computer; Said ECG Signal Analysis model is used for the electrocardiosignal of detected object is analyzed; Export corresponding electrocardiosignal characteristic parameter, said electrocardiosignal characteristic parameter comprises position that P point in the electrocardiosignal, Q point, R point, S point and T are ordered and heart rate, P wave width, QRS complex wave width, T wave width, RR interval, PR interval, ST interval and QT interval; Said analysis of PCG Signal model is used for the cardiechema signals of detected object is analyzed, and exports corresponding cardiechema signals characteristic parameter, and said cardiechema signals characteristic parameter comprises the width and the amplitude of first heart sound, second heart sound, third heart sound and fourth heart sound; Said thoracic impedance signal analytical model is used for the thoracic impedance signal of detected object is analyzed, and exports corresponding thoracic impedance signal characteristic parameter, and said thoracic impedance signal characteristic parameter comprises the position that A point in the thoracic impedance signal, B point, C point, X point and O are ordered; Said parameters of left ventricular function function model is used for obtaining according to said electrocardiosignal characteristic parameter, cardiechema signals characteristic parameter and the analysis of thoracic impedance signal characteristic parameter the index parameter of corresponding cardiac pumping function, cardiac systolic function and cardiovascular function;
B) electrocardiosignal, cardiechema signals and the thoracic impedance signal through the ecg signal acquiring module, cardiechema signals acquisition module and the breast impedance collection module synchronous acquisition detected object that are connected with middle control computer data communication and transfer to middle control computer;
C) in control computer with electrocardiosignal, cardiechema signals and the thoracic impedance signal of synchronous acquisition respectively as the input of ECG Signal Analysis model, analysis of PCG Signal model and thoracic impedance signal analytical model; Again with the input of electrocardiosignal characteristic parameter, cardiechema signals characteristic parameter and the thoracic impedance signal characteristic parameter of ECG Signal Analysis model, analysis of PCG Signal model and the output of thoracic impedance signal analytical model as the parameters of left ventricular function function model; Obtain the index parameter of cardiac pumping function, cardiac systolic function and the cardiovascular function of detected object, and show in real time.
5. cardiac function noinvasive detection method according to claim 4; It is characterized in that; In said steps A) in; In middle control computer, also be provided with sample individual information data base and individual penalty function model in advance; Said individual information data base is used to store the individual information of the detected object of typing, and said individual penalty function model is used to write down the Function Mapping relation of individual information of offset and the detected object of cardiac pumping function index parameter, cardiac systolic function index parameter and index of cardiovascular performance parameter; At said step C) in; After middle control computer is resolved the index parameter of the cardiac pumping function, cardiac systolic function and the cardiovascular function that obtain detected object; Also with the individual information of detected object as the input of individual penalty function and obtain the offset of cardiac pumping function index parameter, cardiac systolic function index parameter and index of cardiovascular performance parameter; Utilize said offset respectively cardiac pumping function index parameter, cardiac systolic function index parameter and the index of cardiovascular performance parameter of corresponding detected object to be compensated and corrected; The index parameter of the cardiac pumping function of the detected object that obtains revising, cardiac systolic function and cardiovascular function, and show in real time.
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