CN102614315B - Compound sleeping-improving capsule and preparation method thereof - Google Patents
Compound sleeping-improving capsule and preparation method thereof Download PDFInfo
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- CN102614315B CN102614315B CN 201210121529 CN201210121529A CN102614315B CN 102614315 B CN102614315 B CN 102614315B CN 201210121529 CN201210121529 CN 201210121529 CN 201210121529 A CN201210121529 A CN 201210121529A CN 102614315 B CN102614315 B CN 102614315B
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Abstract
The invention discloses a compound sleeping-improving capsule and a preparation method thereof, which relate to a sleeping-improving product and a preparation method thereof and are used for solving the problems of dependence and side effect of most conventional sleeping-improving products. The compound sleeping-improving capsule is prepared from 45-55 parts by mass of an extract and 45-55 percent of pregelatinized starch, wherein the extract is prepared from 30-35 percent by mass of Chinese magnoliavine fruit, 20-25 percent by mass of acanthopanax root, 5-10 percent by mass of thinleaf milkwort root-bark, 10-15 percent by mass of spina date seed, 20-25 percent by mass of barbary wolfberry fruit and 5-10 percent of a Chinese date extract. The method comprises the following steps of: smashing raw materials such as Chinese magnoliavine fruit; extracting with a decoction method; concentrating an extracted substance into an extract; and preparing a capsule. The product contains various extracts, has the effect of improving sleeping, and contains rich nutrients. The product has the advantages of simple preparation process, low cost, good economic benefit and easiness for popularizing.
Description
Technical field
The present invention relates to a kind of product that improves sleep and preparation method thereof.
Background technology
Along with the development of society, people's life stress increases day by day, because the impact of various factors, sleep disorder and the phenomenon of not having enough sleep are also more and more general.
The most frequently used method for the treatment of sleep disorder is that although have certain effect, long-term taking can produce certain dependency and side effect with chemosynthesis class sedative hypnotic at present.Active component in the natural plants more and more is subject to extensive concern because its side effect is little, safe, it is wide to adapt to.In recent years domestic research worker conducts a research to the sedative-hypnotic effect of Chinese herbal medicine, finds that many active component wherein have the effect of tranquillizing and allaying excitement.
Summary of the invention
The invention discloses a kind of compound improvement sleep medicine and preparation method thereof, solved most of existing improvement sleep products and had the problem of dependency and side effect.This product contains multiple extract, except the effect that is improved sleep, also contains multiple abundant nutrient.
The compound sleeping capsule that improves of the present invention is made by 45 ~ 55% extract extractum and 45 ~ 55% pregelatinized Starch by mass percentage, and wherein extract extractum is made by 30 ~ 35% Fructus Schisandrae Chinensis, 20 ~ 25% Radix Et Caulis Acanthopanacis Senticosis, 5 ~ 10% Radix Polygalaes, 10 ~ 15% Semen Ziziphi Spinosaes, 20 ~ 25% Fructus Lyciis and 5 ~ 10% Fructus Jujubae extracts by mass percentage.
Compound improvement sleep medicine of the present invention prepares according to the following steps:
1) prepares each extract of main minute: take by weighing Fructus Schisandrae Chinensis, Radix Et Caulis Acanthopanacis Senticosi, Radix Polygalae, Semen Ziziphi Spinosae, Fructus Lycii, Fructus Jujubae fine powder, after its even mixing, ratio with solid-liquid ratio 1g:3 ~ 5ml adds water, boil 1 hour with slow fire, then filter, repeat to boil 3 times, merge extractive liquid, also is concentrated into paste, gets each mixed extract of main minute for subsequent use.
2) by mass percentage 45 ~ 55% extractum and 45 ~ 55% pregelatinized Starch mix homogeneously, and put into vacuum drying oven and dry, the mixture of drying is pulverized, sieve, incapsulate and namely get the compound sleeping capsule goods that improve.
Contain the effective ingredient such as lignanoids 29 ~ 40mg, organic acid 313 ~ 325mg, polysaccharide 465 ~ 475mg, Saponin class 826 ~ 835mg, flavonoid 514 ~ 525mg, flavonoid glycoside 61 ~ 70mg in the compound improvement sleep of the every 100g electuary.
Used raw material Fructus Schisandrae Chinensis, Radix Et Caulis Acanthopanacis Senticosi, Radix Polygalae, Semen Ziziphi Spinosae, Fructus Lycii, the Fructus Jujubae of this product is the health food of the medicine-food two-purpose of Ministry of Public Health announcement, they not only have the effect of tranquillizing and allaying excitement, and at aspects such as improving immunity of organisms, angiocardiopathy preventing good effect are arranged.Fructus Schisandrae Chinensis has obvious tranquilizing effect, can also the strong liver of QI invigorating, efficient, supply more oxygen, the memory that improves of promoting the cells exclude refuse; Modern medicine studies have shown that effect characteristics and the Radix Ginseng of Radix Et Caulis Acanthopanacis Senticosi is basic identical, has that to regulate body disorderly, makes it to be tending towards normal function, have good calm the nerves, antifatigue effect, and can significantly improve hypoxia-bearing capability; Radix Polygalae has the effects such as calmness, blood pressure lowering, promotion muscle power and intelligence; Semen Ziziphi Spinosae has mind tranquilizing and the heart calming, blood pressure lowering, blood fat reducing, anti-hypoxia, enhancing immunologic function and to the protective effect of heart; Fructus Lycii also has the enhancing human body immunity function, suppresses tumor, blood sugar lowering, blood fat reducing, the functions such as resisting fatigue; Fructus Jujubae can also improve body immunity, reduces serum cholesterol, improve serum albumin, the liver protecting except mind tranquilizing and the heart calming.
The present invention carries out scientific and reasonable compatibility with Fructus Schisandrae Chinensis, Radix Et Caulis Acanthopanacis Senticosi, Radix Polygalae, Semen Ziziphi Spinosae, Fructus Lycii, Fructus Jujubae, makes it to act on different target spot in the body, forms many target spot mechanism, thereby produces the good sleeper effect that improves.Compare with other improvement sleep product, this product has the following advantages:
1) scientific formulation is reasonable.Product of the present invention carries out reasonable preparation take effective ingredient such as flavone, Saponins as index, and good effect is not only arranged, and has guaranteed its safety.
2) several materials in the compound improvement sleep electuary have synergism, and they act on the different target spots of body, obtain the good sleeper effect that improves.
3) the product scope of application is wide.The present invention with Fructus Schisandrae Chinensis, Radix Et Caulis Acanthopanacis Senticosi, Radix Polygalae, Semen Ziziphi Spinosae, Fructus Lycii, Fructus Jujubae extract made and improved sleeping capsule, because these several materials all belong to the article of medicine-food two-purpose, the effect that human body is produced does not have physical difference, is fit to most crowds.
4) production technique of the present invention is simple, with low cost, economic benefit good, be easy to popularization.
5) the present invention is easy to carry about with one, instant.
The compound effect (table 1) of improving sleeping capsule: the compound sleeping capsule that improves sooner or later respectively takes one every day, takes 14 days, and observation in the 15th ~ 21 day has obvious curative effect.Volunteer's sleep quality has clear improvement, and time for falling asleep shortens, and prolong the length of one's sleep, without obvious adverse reaction.The volunteer is the student in school and teacher, is the insomniac due to be a cup too low disease and the severe organic disease, does not take antipsychotics taking this product the last fortnight, and does not have major disease.
Table 1
| Group | Total number of persons | Age | Take front symptom | Take rear symptom | The responder | Effective percentage |
| 1 | 45 | 19~40 | Sleep quality is bad, dreaminess | Sleep quality improves, few dream | 31 | 68.9% |
| 2 | 40 | 23~45 | Difficulty falling asleep | Time for falling asleep obviously shortens | 24 | 60% |
| 3 | 40 | 24~50 | The length of one's sleep is short | Prolong the length of one's sleep, and morning, wake-up time postponed | 25 | 62.5% |
Annotate: this product non-drug, generic health product.
The specific embodiment
The specific embodiment one: the compound sleeping capsule that improves is made by 45 ~ 55% extract extractum and 45 ~ 55% pregelatinized Starch by mass percentage in the present embodiment.Wherein extract extractum is made by 30 ~ 35% Fructus Schisandrae Chinensis, 20 ~ 25% Radix Et Caulis Acanthopanacis Senticosis, 5 ~ 10% Radix Polygalaes, 10 ~ 15% Semen Ziziphi Spinosaes, 20 ~ 25% Fructus Lyciis and 5 ~ 10% Fructus Jujubae extracts by mass percentage.
Every 100g improves lignanoids 29 ~ 40mg, organic acid 313 ~ 325mg, polysaccharide 465 ~ 475mg, Saponin class 826 ~ 835mg, flavonoid 514 ~ 525mg, the flavonoid glycoside 61 ~ 70mg in the sleep electuary.
The specific embodiment two: the compound sleeping capsule that improves prepares according to the following steps in the present embodiment:
1) prepares each extract of main minute: take by weighing Fructus Schisandrae Chinensis 30%, Radix Et Caulis Acanthopanacis Senticosi 24%, Radix Polygalae 8%, Semen Ziziphi Spinosae 10%, Fructus Lycii 20%, Fructus Jujubae 8% fine powder, ratio with solid-liquid ratio 1g:3ml ~ 1g:5ml adds water, boil 1 hour with slow fire, then filter, repeat to boil 3 times, merge extractive liquid, also is concentrated into paste, gets each extract of main minute for subsequent use.
2) by 45% extractum and 55% pregelatinized Starch mix homogeneously, and put into vacuum drying oven and dry, the mixture of drying is pulverized, sieve, incapsulate and namely get the compound sleeping capsule that improves.
Wherein, compound lignanoids 29.4mg, organic acid 312.667mg, polysaccharide 465.02mg, Saponin class 826.42mg, flavonoid 513.6mg, the flavonoid glycoside 61.2mg in the sleeping capsule of improving that improves in the sleeping capsule of per 100 grams.
The specific embodiment three: present embodiment and embodiment one, two different be that the mass percent of each raw material is Fructus Schisandrae Chinensis 32%, Radix Et Caulis Acanthopanacis Senticosi 22%, Radix Polygalae 8%, Semen Ziziphi Spinosae 12%, Fructus Lycii 20%, Fructus Jujubae 6%.
The specific embodiment four: present embodiment and embodiment one, two, three different be that the mass percent of each raw material is Fructus Schisandrae Chinensis 34%, Radix Et Caulis Acanthopanacis Senticosi 20%, Radix Polygalae 6%, Semen Ziziphi Spinosae 11%, Fructus Lycii 22%, Fructus Jujubae 7%.
The specific embodiment five: present embodiment and embodiment one, two, three, four different be that the mass percent of each raw material is Fructus Schisandrae Chinensis 35%, Radix Et Caulis Acanthopanacis Senticosi 23%, Radix Polygalae 7%, Semen Ziziphi Spinosae 10%, Fructus Lycii 20%, Fructus Jujubae 5%.
Claims (6)
1. the compound sleeping capsule that improves, it is characterized in that described capsule made by 45 ~ 55% extract extractum and 45 ~ 55% pregelatinized Starch by mass percentage, wherein extract extractum is made by 30 ~ 35% Fructus Schisandrae Chinensis, 20 ~ 25% Radix Et Caulis Acanthopanacis Senticosis, 5 ~ 10% Radix Polygalaes, 10 ~ 15% Semen Ziziphi Spinosaes, 20 ~ 25% Fructus Lyciis and 5 ~ 10% Fructus Jujubae extracts by mass percentage.
2. the compound sleeping capsule that improves according to claim 1, the mass percent that it is characterized in that described extract extractum is Fructus Schisandrae Chinensis 30%, Radix Et Caulis Acanthopanacis Senticosi 24%, Radix Polygalae 8%, Semen Ziziphi Spinosae 10%, Fructus Lycii 20%, Fructus Jujubae 8%.
3. the compound sleeping capsule that improves according to claim 1, the mass percent that it is characterized in that described extract extractum is Fructus Schisandrae Chinensis 32%, Radix Et Caulis Acanthopanacis Senticosi 22%, Radix Polygalae 8%, Semen Ziziphi Spinosae 12%, Fructus Lycii 20%, Fructus Jujubae 6%.
4. the compound sleeping capsule that improves according to claim 1, the mass percent that it is characterized in that described extract extractum is Fructus Schisandrae Chinensis 34%, Radix Et Caulis Acanthopanacis Senticosi 20%, Radix Polygalae 6%, Semen Ziziphi Spinosae 11%, Fructus Lycii 22%, Fructus Jujubae 7%.
5. the compound sleeping capsule that improves according to claim 1, the mass percent that it is characterized in that described extract extractum is Fructus Schisandrae Chinensis 35%, Radix Et Caulis Acanthopanacis Senticosi 23%, Radix Polygalae 7%, Semen Ziziphi Spinosae 10%, Fructus Lycii 20%, Fructus Jujubae 5%.
6. described compound preparation method of improving sleeping capsule of claim 1 is characterized in that described method is:
1) prepares the extract of each component: take by weighing Fructus Schisandrae Chinensis, Radix Et Caulis Acanthopanacis Senticosi, Radix Polygalae, Semen Ziziphi Spinosae, Fructus Lycii, Fructus Jujubae fine powder in the described ratio of claim 1, after its even mixing, ratio with solid-liquid ratio 1g:3 ~ 5ml adds water, boil with slow fire, then filter, repeat to boil 3 times, merge extractive liquid, also is concentrated into paste, and the mixed extract extractum that gets each component is for subsequent use;
2) be the ratio mix homogeneously of 45 ~ 55% extract extractum and 45 ~ 55% pregelatinized Starch by mass percentage, and put into vacuum drying oven and dry, the mixture of drying is pulverized, sieve, incapsulate and namely get the compound sleeping capsule that improves.
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| CN 201210121529 CN102614315B (en) | 2012-04-24 | 2012-04-24 | Compound sleeping-improving capsule and preparation method thereof |
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| CN102614315B true CN102614315B (en) | 2013-10-16 |
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| CN103202896A (en) * | 2013-02-04 | 2013-07-17 | 北华大学 | Tranquillizing, allaying and sleep-promoting oral liquid and preparation method thereof |
| CN107334142A (en) * | 2017-06-23 | 2017-11-10 | 天津金匮堂生物科技有限公司 | A kind of deficiency of heart-blood that improves causes health products of insomnia and preparation method thereof |
| CN108338297A (en) * | 2018-01-31 | 2018-07-31 | 佳木斯大学 | A kind of mind-tranquilizing brain-strengthening health beverages and preparation method thereof |
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| CN101156922A (en) * | 2006-10-08 | 2008-04-09 | 天津市正道中医咨询服务中心 | A traditional Chinese medicine composition for treating insomnia |
| CN101273792A (en) * | 2008-04-18 | 2008-10-01 | 陈春祥 | Sanzi oral liquid and its preparing process |
| CN101642176A (en) * | 2009-06-11 | 2010-02-10 | 杭州六易科技有限公司 | Method for preparing wild jujube honey tea for relieving neurasthenia |
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2012
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Patent Citations (5)
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|---|---|---|---|---|
| CN1330892A (en) * | 2000-06-26 | 2002-01-16 | 李秉懿 | Qijia Beverage and oral liquid and preparing process thereof |
| CN101156922A (en) * | 2006-10-08 | 2008-04-09 | 天津市正道中医咨询服务中心 | A traditional Chinese medicine composition for treating insomnia |
| CN101095739A (en) * | 2007-07-23 | 2008-01-02 | 南京加捷生物科技有限公司 | Health-care tea for improving sleep function |
| CN101273792A (en) * | 2008-04-18 | 2008-10-01 | 陈春祥 | Sanzi oral liquid and its preparing process |
| CN101642176A (en) * | 2009-06-11 | 2010-02-10 | 杭州六易科技有限公司 | Method for preparing wild jujube honey tea for relieving neurasthenia |
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| 周仲瑛主编.不寐.《中医内科学》.中国中医药出版社,2007,第150页. * |
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