CN102580048B - Chinese medicine for losing weight and preparation method thereof - Google Patents
Chinese medicine for losing weight and preparation method thereof Download PDFInfo
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Abstract
The invention provides a Chinese medicine for losing weight. The Chinese medicine comprises hawthorn fruit, plantain herb, kelp, inula flower, unibract fritillary bulb, rhubarb, zedoary, gambir plant, Chinese magnoliavine fruit, cattail pollen, weeping forsythia, lotus leaf, Chinese taxillus twig, motherwort herb, carbonized human hair, aloes, desertliving cistanche, knoxia root, dried ginger, cassia bark, astragalus, siberian solomonseal rhizome, ladybell root, dendrobium and szechwan chinaberry fruit. The Chinese medicine has the advantages that: a weight-losing effect is obvious, a side effect is avoided, and the health of bodies is facilitated.
Description
Technical field
The present invention relates to the pharmaceutical engineering technical field, relate in particular to a kind of Chinese medicine for fat-reducing.
Background technology
WHO had been declared as obesity a kind of disease in 1997, be a kind of not only developing country but also popular in developed country, not only influenced child but also influence adult's disease, in the U.S., there are 300,000 people to die from and fat diseases associated every year on average approximately, in China, along with Body Mass Index from low to high, cardiovascular disease sickness rate ascendant trend linearly, its sickness rate is 10%～20%.Obesity not only influences figure and activity, and the sickness rate of overweight people's cardiovascular and cerebrovascular disease, diabetes, liver and gall diseases and cancer etc. is all than the normal person's height of body weight.Therefore, prevention and the treatment of obesity are generally paid attention to, WHO has confirmed that obesity will become the first health problem in the whole world.
The fat cause of disease and pathogenesis still imperfectly understand, may be relevant with following factors.Inherited genetic factors, epidemiology show that some overweight people has family's morbidity tendency.The neural factor of spirit, zoopery and clinical observation show that nervous and mental factors is to people's the regulating action of having ingested.Endocrine factors, many hormones such as thyroxine, insulin, glucocorticoid etc. may participate in pathogenic mechanism of obesity.Life style and dietary habit do not like that movable people's consumed energy reduces, and easily take place fat.The athlete is after stop motion, often take the photograph the high calorie diet of people or heavy, smoker after smoking cessation, feeding habits, the greasy food of liking consuming oil, the every day few and every meal food-intake of number of times of having meal of advancing of sleeping is big etc. all relevant with the generation of Simple Obesity, but is not unique cause of disease.
At present, all there is the defective of each side in the fat Western medicine for the treatment of.The representative medicine of appetite suppressant is fenfluramine.Appetite suppressant studies confirm that through multinomial, and this type of medicine can cause serious adverse reactions such as damaged heart valve, pulmonary hypertension and finger necrosis, and other can influence catecholamine and one simultaneously as the quick ware coffee of sibutramine cangue.This medicine blood pressure that can raise has the obese patient Ying Shenyong of cardiovascular disease.Increase the central stimulants of energy expenditure, as ephedrine, theophylline, caffeine etc. the rising blood pressure is arranged also, speed side effect such as heart rate.Lipase inhibitor one orlistat is a kind of potent gastrointestinal tract lipase inhibitor, can stop fat molecule to decompose and reduces its absorption.But such medicine can cause functional gastrointestinal disorder, fatiguability etc., also influences the absorption of fatsoluble vitamin.Acarbose is the general enzyme inhibitor of a glucose by suppressing glucose former times enzyme competitively in small intestinal, and reduces the absorption of carbohydrate.
Chinese medicine can pass through to increase heat loss, thereby loses weight; Nutritional labeling is separated, made the absorption kilocalorie directly enter muscle rather than fatty tissue, therefore adopt the treatment by Chinese herbs obesity to have many advantages that Western medicine does not have.
The principle of Chinese medicine fat-reducing mainly shows: 1, reduce exogenous lipid absorption, reduce the synthetic of endogenous lipid; 2, by excited maincenter, increase the consumption of feeling of repletion or increase energy.
Summary of the invention
Technical problem to be solved by this invention is, overcomes the deficiency of existing treatment, utilizes the traditional theory of Chinese medical science of China, and a kind of new-type traditional Chinese compositions is provided, its aspect fat-reducing, have effect significantly, have no side effect, be conducive to able-bodied advantage.
Ask in order to solve above-mentioned technology, the invention provides a kind of fat-reducing Chinese medicine, it is made up of Fructus Crataegi, Herba Plantaginis, Thallus Laminariae (Thallus Eckloniae), Flos Inulae, Bulbus Fritillariae Cirrhosae, Radix Et Rhizoma Rhei, Rhizoma Curcumae, Ramulus Uncariae Cum Uncis, Fructus Schisandrae Chinensis, Pollen Typhae, Fructus Forsythiae, Folium Nelumbinis, Herba Taxilli, Herba Leonuri, Crinis Carbonisatus, Aloe, Herba Cistanches, Radix Knoxiae, Rhizoma Zingiberis, Cortex Cinnamomi, the Radix Astragali, Rhizoma Polygonati, Radix Adenophorae, Herba Dendrobii and Fructus Toosendan.
Wherein, the ratio of weight and number of each component in the described Chinese medicine is Fructus Crataegi 15～25 weight portions, Herba Plantaginis 15～25 weight portions, Thallus Laminariae (Thallus Eckloniae) 70～80 weight portions, Flos Inulae 20～30 weight portions, Bulbus Fritillariae Cirrhosae 20～30 weight portions, Radix Et Rhizoma Rhei 25～35 weight portions, Rhizoma Curcumae 30～40 weight portions, Ramulus Uncariae Cum Uncis 70～80 weight portions, Fructus Schisandrae Chinensis 10～20 weight portions, Pollen Typhae 30～40 weight portions, Fructus Forsythiae 20～30 weight portions, Folium Nelumbinis 20～30 weight portions, Herba Taxilli 20～30 weight portions, Herba Leonuri 30～40 weight portions, Crinis Carbonisatus 30～40 weight portions, Aloe 15～25 weight portions, Herba Cistanches 10～20 weight portions, Radix Knoxiae 15～25 weight portions, Rhizoma Zingiberis 15～25 weight portions, Cortex Cinnamomi 15～25 weight portions, the Radix Astragali 35～45 weight portions, Rhizoma Polygonati 35～45 weight portions, Radix Adenophorae 20～30 weight portions, Herba Dendrobii 20～30 weight portions and Fructus Toosendan 10～20 weight portions.
Wherein, the ratio of weight and number of each component in described Chinese medicine Fructus Crataegi 20～25 weight portions more preferably, Herba Plantaginis 20～25 weight portions, Thallus Laminariae (Thallus Eckloniae) 75～80 weight portions, Flos Inulae 25～30 weight portions, Bulbus Fritillariae Cirrhosae 25～30 weight portions, Radix Et Rhizoma Rhei 30～35 weight portions, Rhizoma Curcumae 35～40 weight portions, Ramulus Uncariae Cum Uncis 75～80 weight portions, Fructus Schisandrae Chinensis 15～20 weight portions, Pollen Typhae 35～40 weight portions, Fructus Forsythiae 25～30 weight portions, Folium Nelumbinis 25～30 weight portions, Herba Taxilli 25～30 weight portions, Herba Leonuri 35～40 weight portions, Crinis Carbonisatus 35～40 weight portions, Aloe 20～25 weight portions, Herba Cistanches 15～20 weight portions, Radix Knoxiae 20～25 weight portions, Rhizoma Zingiberis 20～25 weight portions, Cortex Cinnamomi 20～25 weight portions, the Radix Astragali 40～45 weight portions, Rhizoma Polygonati 40～45 weight portions, Radix Adenophorae 25～30 weight portions, Herba Dendrobii 25～30 weight portions and Fructus Toosendan 15～20 weight portions.
Wherein, the ratio of weight and number of each component in described Chinese medicine Fructus Crataegi 22 weight portions more preferably, Herba Plantaginis 22 weight portions, Thallus Laminariae (Thallus Eckloniae) 78 weight portions, Flos Inulae 28 weight portions, Bulbus Fritillariae Cirrhosae 28 weight portions, Radix Et Rhizoma Rhei 32 weight portions, Rhizoma Curcumae 38 weight portions, Ramulus Uncariae Cum Uncis 78 weight portions, Fructus Schisandrae Chinensis 18 weight portions, Pollen Typhae 38 weight portions, Fructus Forsythiae 28 weight portions, Folium Nelumbinis 28 weight portions, Herba Taxilli 28 weight portions, Herba Leonuri 38 weight portions, Crinis Carbonisatus 38 weight portions, Aloe 22 weight portions, Herba Cistanches 18 weight portions, Radix Knoxiae 22 weight portions, Rhizoma Zingiberis 22 weight portions, Cortex Cinnamomi 22 weight portions, the Radix Astragali 42 weight portions, Rhizoma Polygonati 42 weight portions, Radix Adenophorae 28 weight portions, Herba Dendrobii 28 weight portions and Fructus Toosendan 18 weight portions.
The present invention also provides above-mentioned preparation method of Chinese medicine, and when the dosage form of described Chinese medicine was tablet, it may further comprise the steps,
The first step, described component is pressed described mixed, add the deionized water with respect to 3～6 times of described mixture qualities, decocted 2～4 hours, filter, in the filtering residue that obtains, further add the deionized water with respect to 0.5～1 times of described mixture quality, decocted again 1～2 hour, and filtered, with the filtrate mixing of twice acquisition, carry out concentrating under reduced pressure, relative density is 1.29～1.32 mastic when being concentrated into temperature and being 70 ℃;
Second step, in the mastic that the first step obtains, add determining alcohol with respect to 3～5 times of mastic quality and be 85%～95% ethanol, stirring and dissolving obtains alcoholic solution, alcoholic solution was left standstill 24～36 hours under 5 ℃～10 ℃ condition, adopt percolation with the speed of per minute 1～2ml percolation slowly, collect percolate, concentrate and drying, be ground into powder;
The 3rd step was ground into 50 order to 100 purpose fine powders with the powder that obtains, and with respect to the starch of 0.3～0.6 times of the quality of the fine powder that obtains, mix homogeneously is granulated subsequently, drying, and tabletting makes tablet.。
The present invention also provides above-mentioned preparation method of Chinese medicine, and when described form of Chinese drug was drop pill, it may further comprise the steps,
The first step, described component is pressed described mixed, add the deionized water with respect to 3～6 times of described mixture qualities, decocted 2～4 hours, filter, in the filtering residue that obtains, further add the deionized water with respect to 0.5～1 times of described mixture quality, decocted again 1～2 hour, and filtered, with the filtrate mixing of twice acquisition, carry out concentrating under reduced pressure, relative density is 1.29～1.32 mastic when being concentrated into temperature and being 70 ℃;
Second step, in the mastic that the first step obtains, add determining alcohol with respect to 3～5 times of mastic quality and be 85%～95% ethanol, stirring and dissolving obtains alcoholic solution, alcoholic solution was left standstill 24～36 hours under 5 ℃～10 ℃ condition, adopt percolation with the speed of per minute 1～2ml percolation slowly, collect percolate, concentrate and drying, be ground into powder;
The 3rd step, get the powder of second step acquisition of 100 weight portions, the Macrogol 4000 of 100～200 weight portions, the methyl-silicone oil of 5～10 weight portions, powder is added water make even pasty state, add the Macrogol 4000 substrate liquid that dissolves again, heating and melting becomes supernatant liquid, pour in the drop pill device of preheating, temperature processed and speed are dripped in control, splash in the methyl-silicone oil condensed fluid, blot condensed fluid after becoming ball, collect drop pill, put in the exsiccator, namely get drop pill.
The present invention also provides above-mentioned preparation method of Chinese medicine, and when the dosage form of described Chinese medicine was electuary, it may further comprise the steps,
The first step, described component is pressed described mixed, add the deionized water with respect to 3～6 times of described mixture qualities, decocted 2～4 hours, filter, in the filtering residue that obtains, further add the deionized water with respect to 0.5～1 times of described mixture quality, decocted again 1～2 hour, and filtered, with the filtrate mixing of twice acquisition, carry out concentrating under reduced pressure, relative density is 1.29～1.32 mastic when being concentrated into temperature and being 70 ℃;
Second step, in the mastic that the first step obtains, add determining alcohol with respect to 3～5 times of mastic quality and be 85%～95% ethanol, stirring and dissolving obtains alcoholic solution, alcoholic solution was left standstill 24～36 hours under 5 ℃～10 ℃ condition, adopt percolation with the speed of per minute 1～2ml percolation slowly, collect percolate, concentrate and drying, be ground into powder;
In the 3rd step, with described powder and glucose, sucrose mixing, obtain the electuary finished product; The weight ratio of described powder and described glucose, sucrose is 10: 1～4: 1～6.
Wherein, the dosage form of described Chinese medicine is electuary, tablet or drop pill.
Beneficial effect of the present invention:
With respect to slimming medicine of the prior art, adopt this Chinese medicine aspect fat-reducing, have effect significantly, have no side effect, be conducive to able-bodied advantage.
The specific embodiment
Traditional Chinese medical science ancient books is very few to specially stating of obesity, the argumentation of having only some to be dispersed in, and dialectical do not have unified suggestion as yet yet, and most patients are except body is too fat to move, and all the other, and not have institute bitter, therefore brings certain difficulty to treatment.Obesity is the card of simulataneous insufficiency and excessive, deficiency in origin and excess in superficiality, and pathology is mainly excessive phlegm and weak breath two aspects.So-called " fertile people's excessive phlegm ", " the many stasis of bloods of fertile people " are the one sides of its domination of pathogen, wet poly-expectorant is given birth to, and the long-pending stasis of blood resistance of fat causes expectorant fat to be detained between the skin of the whole body, among the peritoneum, within the internal organs, cream fat smoulders and must make obstruction of QI, give birth to expectorant stasis of blood homology, vicious cycle in the blood stasis, then fat all diseases are grown thickly, as for weak breath, on the one hand because of Lack of Movement, cause the deficiency of vital energy; Obesity becomes on the other hand, and cream fat is cohesion, transfers imbalance, and having no way of of qi-blood-body fluid given birth to, and causes the deficiency of vital energy; Basic reason is the deficiency of vital energy, and yang-energy is not transported, and sick position is at spleen.Say as Wang Ang: " fertile people's excessive phlegm and through the resistance, gas is not transported yet "; " the secret record in stone chamber " also cloud: " fertile people's excessive phlegm, be the deficiency of vital energy also, void then blood can not be moved, so the expectorant life ".The spleen has the function to transport and transform nutrients for lid, is source of generating QI and blood, and spleen fortune is normal, and essence of water and grain is failed the cloth whole body, nutrition extremity bones of the body collectively; Insufficiency of the spleen mistake fortune is not precise and tinyly changed, and wet poly-expectorant is given birth to, the long-pending stasis of blood resistance of fat.And phlegm-damp stasis of blood fat is all YIN pathogen, and non-temperatureization then is difficult to its heresy that disappears." sick phlegm retention person when with warm medicine and it ", based on this, the present invention effects a permanent cure based on needle warming moxibustion in order to the Chinese medicine composition of losing weight, and reduces phlegm to control its mark except the stasis of blood is double.
The invention provides a kind of fat-reducing Chinese medicine, it is made up of Fructus Crataegi, Herba Plantaginis, Thallus Laminariae (Thallus Eckloniae), Flos Inulae, Bulbus Fritillariae Cirrhosae, Radix Et Rhizoma Rhei, Rhizoma Curcumae, Ramulus Uncariae Cum Uncis, Fructus Schisandrae Chinensis, Pollen Typhae, Fructus Forsythiae, Folium Nelumbinis, Herba Taxilli, Herba Leonuri, Crinis Carbonisatus, Aloe, Herba Cistanches, Radix Knoxiae, Rhizoma Zingiberis, Cortex Cinnamomi, the Radix Astragali, Rhizoma Polygonati, Radix Adenophorae, Herba Dendrobii and Fructus Toosendan.
Further, described fat-reducing Chinese medicine only is made of said components.
Each component pharmacology is as follows:
Fructus Crataegi: sour in the mouth, sweet, slightly warm in nature is returned spleen, stomach, Liver Channel, is used for promoting digestion and invigorating the stomach, and the circulation of qi promoting dissipating blood stasis is mainly used to treat accumulation of food in the stomach and intes tine due to indigestion, has loose bowels, dysentery, Fructus Crataegi is the staple for the treatment of dyspepsia, Fructus Crataegi can increase the secretion of peptic digestion enzyme, facilitating digestion; Dysentery bacterium, escherichia coli, bacillus pyocyaneus, staphylococcus aureus etc. are had the obvious suppression effect, and Fructus Crataegi has stronger blood fat reducing and eliminates the effect of superfluous fat in the body.
Herba Plantaginis: sweet in the mouth, light, cold nature is returned lung, liver, kidney, urinary bladder channel, the effect that have clearing away heat and promoting diuresis, eliminating dampness by diuresis antidiarrheal, makes eye bright and eliminate the phlegm cures mainly dysuria, the stranguria with turbid discharge leukorrhagia, the edema distension, the heat-damp in summer dysentery, conjunctival congestion is hidden from view, the expectorant heat syndrome cough such as breathes heavily at card, " book on Chinese herbal medicine converges and says ": Semen Plantaginis, the row liver is dredged kidney, and is smooth strongly fragrant and positive, with kidney-reinforcing drug usefulness, make reinforcing YIN-essence that son is arranged; Medicinal with regulating liver-QI, control the conjunctival congestion blurred vision; With antipyretic usefulness, dysentery relieving disease fire stagnation; With Shujin is medicinal can promoting diuresis to eliminate dampness and promoting QI circulation, the sufficient knee joint of strong fortune has testing also that speed answers.Celebrate a festival if feelings are moving, bladder void, gas is difficult in change and Tianjin is not all right, the person that can drowns, and singly uses the Herba Plantaginis catharsis, closes more, must add ginseng, Siberian cocklebur, sweet, wheat, the controlling desire of fostering the spirit of nobility, then Tianjin voluntarily, excessive is also.
Thallus Laminariae (Thallus Eckloniae): salty in the mouth, cold in nature, return liver, stomach, kidney channel, have hard masses softening and resolving, the effect of expectorant diuretic, be used for goiter, scrofula, painful and swollen testis, cards such as phlegm retention edema, its content that can suppress hyperlipidemia chicken serum T-CHOL, triglyceride significantly rises, and can reduce formation and the development of chicken aortic tunica intima atheromatous plaque, can be used for treatment of obesity.
Flos Inulae: bitter in the mouth, suffering, salty, slightly warm in nature is returned lung, stomach, large intestine channel, have the sending down the abnormal ascending QI expectorant, the effect of row water preventing or arresting vomiting is used for the cough due to wind and cold, phlegm retention is held knot, chest and diaphragm feeling of fullness, dyspnea and cough with excessive sputum, the vomiting eructation, cards such as epigastric oppression and rigidity, " Bencao Jingshu ": Flos Inulae, its first system of flavor with salty, relaxing the bowels with lubricant drugs is done salty, salty energy softening the hard mass; " not Lu " be to sweet taste in the mouth, among the Gan Nenghuan; Tepor, temperature can be passed through, so main stagnation of QI fullness in the hypochondrium; Heart spleen latent fluid-retention is sick palpitation with fear then, and drink disappears then multiple normal.Dewater, remove cold and heat between the five internal organs, and expectorant knot on the breast that disappears, saliva such as shellac varnish, heart side of body expectorant water, wing is prolonged fluid-retention all of a sudden, the pathogenic wind arthralgia chiefly caused by damp pathogen, dead flesh is opened in the order between skin, sharp large intestine person, all the merit that dewaters of softening the hard mass, cold profit, relaxing the bowels with lubricant drugs, expectorant drink is also.It says invigorating middle warmer therapeutic method to keep the adverse QI flowing downwards person, and in delaying with sweet energy, so salty energy relaxing the bowels with lubricant drugs is also.Promoting blood circulation, beneficial color and luster person, lid refers to that the drink spleen that disappears then is strong, and is strong then can move, spleen is wrapped up in the blood blood of uniting again and is died also.
Bulbus Fritillariae Cirrhosae: bitter in the mouth, sweet, cold nature is returned lung, heart channel, has clearing heat and moistening lung, and the effect of preventing phlegm from forming and stopping coughing cures mainly cough due to consumptive disease, card such as the spitting of blood of spitting, ambition pent-up, consumptive lung disease, lung abscess, sore throat, acute mastitis.
Radix Et Rhizoma Rhei: bitter in the mouth, cold in nature, return stomach warp, large intestine channel, Liver Channel, spleen channel, have attack stagnant, clearing away damp-heat, pathogenic fire purging, removing heat from blood, blood stasis dispelling, the effect of detoxifcation cures mainly the excess-heat constipation; The accumulation of heat feeling of stuffiness in chest; Damp-heat dysentery; Jaundice; Gonorrhea; The edema abdominal distention; Dysuria; Conjunctival congestion; Laryngopharynx swelling and pain; Aphtha of the mouth and tongue; Gastropyretic vomiting; Spit blood; Spitting of blood; Epistaxis; Have blood in stool; Hematuria; Blood-retention; Amenorrhea; The stasis of blood stagnated and suffered from abdominal pain puerperal; Lump in the abdomen; Traumatic injury; Pyretic toxicity carbuncle and ulcer; Erysipelas; Cards such as scald, Radix Et Rhizoma Rhei effectively reduce body weight, bluntness, Body Mass Index, serum total cholesterol is superfluous and glycerol three vinegar fly level, can promote lipid mobilization and utilization, regulate lipid metabolism.
Rhizoma Curcumae: acrid in the mouth, hardship, warm in nature, go into liver, spleen channel, have the removing blood stasis circulation of qi promoting, the effect of removing food stagnancy pain relieving is for the lump in the abdomen mass in the abdomen of caused by energy stagnation and blood stasis, breast abdomen stasis of blood pain, amenorrhea, dysmenorrhea, abdominal distention, traumatic injury, blood stasis card such as swell and ache, Rhizoma Curcumae can reduce obese patient's blood glucose and serum leptin level, alleviate fatty weight in wet base, dwindle lipocyte, have good promotion body fat metabolism effect.
Ramulus Uncariae Cum Uncis: sweet in the mouth, slightly warm in nature is gone into Liver Channel, and the effect of heat clearing away, suppressing the hyperactive liver and subsiding YANG, relieving spasm by subduing liver-wind is arranged, be mainly used in the anxious spasm of giving birth to due to wind or the liver-wind stirring up internally of heat, twitch, restlessness, excessive rising of liver-YANG or Liver Channel have the headache of heat dizzy, symptoms such as conjunctival congestion and swelling pain, Ramulus Uncariae Cum Uncis can obviously suppress body constitution amount, the food-intake of high fat obese rat, can reduce free radical, free fatty and serum insulin levels, improves the Total antioxidant capacity of rat.
Fructus Schisandrae Chinensis: sour in the mouth, sweet, warm in nature, go into lung, the heart, kidney channel, have the convergence astringent or styptic treatment for spontaneous sweating, supplementing QI for promoting the production of body fluid, the effect of kidney calming, be used for the chronic cough dyspnea due to deficiency, emission, enuresis frequent micturition, incessant chronic diarrhea, spontaneous perspiration, night sweat, Tianjin wound is thirsty, the deficient pulse of losing heart, interior-heat is quenched one's thirst, palpitation and insomnia.Fructus Schisandrae Chinensis has antiinflammation, and Fructus Schisandrae Chinensis can obviously suppress the increase of removal ovary rat food ration and body constitution amount, reduces total plasma cholesterol, triglyceride and high-density protein.
Pollen Typhae: sweet in the mouth, property is flat, goes into liver, pericardium channel, has hemostasis, blood stasis dispelling, treating stranguria effect.Be used for spitting blood epistaxis, spitting of blood, metrorrhagia, traumatic hemorrhage, amenorrhea dysmenorrhea, gastral cavity ventral spine pain, tumbling and swelling, blood strangury and dry pain.
Fructus Forsythiae: bitter in the mouth, cold nature is gone into lung, the heart, and small intestine meridian has heat-clearing and toxic substances removing, and the effect of dispersing swelling and dissipating binds is used for calentura from the beginning of, anemopyretic cold, and heating is vexed, laryngopharynx swelling and pain, macule, erysipelas, scrofula, carbuncle pyogenic infections from tumour or sore, acute nephritis, pyretic stranguria.The mongolian medicine subcutaneous ulcer of harnessing the Yellow River, cards such as intestinal twinge, Fructus Forsythiae is inhibited to various bacteria, human body is had cooling effect, and tangible antiinflammatory action, Fructus Forsythiae are arranged can be that obesity mice adipose cell diameter diminishes, the jejunum villi surface area reduces, the body weight gain rate reduces, and fat coefficient diminishes, and the alimentary obesity mice is had certain antiobesity action.
Folium Nelumbinis: bitter in the mouth, suffering, little puckery, cool in nature, GUIXIN, liver, spleen channel have summer heat relieving and dampness eliminating, the spleen invigorating yang invigorating, the effect of dissipating blood stasis hemostasis cures mainly the summer-heat excessive thirst, and it is dizzy to have a headache, edema, lack of appetite abdominal distention, dysentery, leucorrhea, proctoptosis is spitted blood, epistaxis, spitting of blood is had blood in stool, metrorrhagia, post partum longtime lochia, cards such as traumatic blood stasis.
Herba Taxilli: bitter in the mouth, sweet, property is flat, goes into liver, kidney channel, effect with invigorating the liver and kidney, bone and muscle strengthening, wind-damp dispelling, antiabortive unit is used for the soreness of waist pain due to the deficiency of the liver and kindey, and the muscles and bones flaccidity is soft, the foot and knee being feeble, deficiency of the liver and kindey, essence and blood is empty to lose the frequent fetal movement of liability to abortion, cards such as waist abdomen pain.
Herba Leonuri: bitter in the mouth, suffering, cold nature is gone into liver, pericardium channel, has promoting blood flow to regulate menstruation, inducing diuresis to remove edema, the effect of heat-clearing and toxic substances removing is used for the menoxenia due to the blood stasis, dysmenorrhea, amenorrhea, puerperal abdonimal pain or lochiorrhea; Edema, dysuria; Traumatic injury, cards such as sore and toxic.
Crinis Carbonisatus: bitter in the mouth, slightly warm in nature, have repercussive, hemostasis, the effect of diuresis cures mainly cards such as haematemesis, epistaxis, dysentery, stranguria with blood, woman uterine bleeding and dysuria." Records of Tradition Chinese and Western Medicine in Combination ": " the Crinis Carbonisatus person sends out also, does not forge then its matter and does not change, and is used as medicine then so must forge to charcoal.Its performance blood stasis dispelling blood, tissue regeneration promoting blood have like Radix Notoginseng, so kind haematemesis, the epistaxis controlled.And informal dress can control tuberculosis, because of the people of tuberculosis, its blood must void and the stasis of blood.
Aloe: bitter in the mouth, cold in nature, return liver, large intestine channel, have rush down down, the effect of liver heat removing, parasite killing.Cure mainly constipation with heat retention; The liver-fire headache; The conjunctival congestion infantile convulsion; Abdominal pain due to worm stagnation; Scabies; Hemorrhoid complicated by anal fistula; Separate cards such as Fructus Crotonis poison.
Herba Cistanches: sweet in the mouth, salty, warm in nature, go into kidney, large intestine channel has kidney-replenishing, benefiting essence-blood, the effect of loosening bowel to relieve constipation, be used for kidney yang deficiency, the impotence and premature ejaculation of asthenia of essence and blood, sterility and infertility, soreness of waist and knee joint, Hiccough and deaf, frequent micturition urine number, suffer from a deficiency of the kidney dryness of the intestine and puerperal blood deficiency, the cards such as constipation of deficiency of body fluid after being ill, can strengthen body fluid and cellular immune function, strengthen the mononuclear phagocyte phagocytic activity.
Radix Knoxiae: bitter in the mouth, cold in nature, return lung meridian, spleen channel, kidney channel, have removing fluid-retention by purgation, the effect of detoxicating and resolving stagnation of pathogens is used for the edema distension, phlegm retention dyspnea with rapid respiration, carbuncle pyogenic infections from tumour or sore, removing fluid-retention by purgation, merit poison dispersing swelling and dissipating binds, breast abdomen hydrops, difficulty in urination and defecation, carbuncle sore tumefacting virus, cards such as scrofula sucutaneous nodule.
Rhizoma Zingiberis: acrid in the mouth, hot in nature, return spleen, stomach, the heart, lung meridian; Have warming spleen and stomach for dispelling cold, recuperating depleted YANG is promoted blood circulation, the dampness expectorant, and the effect of warming the lung to resolve fluid-retention is used for coldness and pain in the epigastrium, and vomiting is had loose bowels, and YANG-depletion is fainted contrary, and cold fluid-retention is breathed with cough, cards such as arthralgia due to cold-dampnes.
Cortex Cinnamomi: extremely hot in nature, acrid in the mouth, sweet is returned kidney, spleen, the heart, Liver Channel, and it is fiery supporing yang to have benefit, let the fire back to its origin, dispersing cold for relieving pain, the effect of promoting blood circulation to restore menstrual flow is used for warming the spleen and stomach, removing accumulated cold, promoting blood circulation.Control decline of the fire from the gate of life, the cold extremities faint pulse, the YANG-depletion collapse, stomachache is had loose bowels, the colic of cold type renal mass, chills and pain of the waist and kness, the amenorrhea lump in the abdomen, carbuncle of yin nature, multiple abscess, and empty sun is more floating, cards such as heat in the upper and cold in the lower
The Radix Astragali: sweet in the mouth, warm in nature, return lung, spleen channel, tonification spleen soil is arranged, the elevate a turnable ladder yang-energy, strengthening superficial resistance to stop perspiration, effects such as holder skin ulcer granulation promoting are mainly used in treating the weak anorexia and loose stool due to the deficiency of both the splenic and pulmonary QI, shortness of breath and palpitation, the visceroptosis of sinking of QI of middle-JIAO, the metrorrhagia of QI failing to control blood is had blood in stool, the chronic diarrhea proctoptosis; The spontaneous sweating of exterior deficiency; Insufficiency of vital energy and blood, yang-energy skin infection on the decline do not rise, difficulty in discharging of pus, burst and not hold back for a long time; And the deficiency of vital energy is lost the edema of fortune; symptoms such as dysuria; the Radix Astragali has dual regulation to animal blood glucose; can increase anemia person's erythrocyte and hemoglobin; promote leukocyte and thrombocytopenia person to recover normal; and can improve or recover erythrocytic function, the immune function of its energy enhancing body.
Rhizoma Polygonati: sweet in the mouth, property is flat, returns lung, spleen, kidney channel has the nourishing kidney lung moistening, the effect of invigorating the spleen and replenishing QI cures mainly deficiency of YIN chronic cough, and the xeropulmonary cough is insufficiency of the spleen weak, and the lack of appetite xerostomia is quenched one's thirst, the deficiency of the kidney soreness of the waist and knees, impotence and seminal emission, the tinnitus order is dark, early whitening of beard and hair, the empty win of body is thin, the effect of wind favus disease.
Radix Adenophorae: sweet in the mouth, little hardship, cold nature, go into lung, stomach warp, nourishing the lung to arrest cough is arranged, and the effect of nourishing the stomach to promote the production of body fluid is mainly used in lung-dryness syndrome due to deficiency of YIN, the few expectorant of dry cough, chronic cough expectorant blood, cards such as deficiency of stomach-Yin, mouthfeel parched throat, constipation, the few tongue of red tongue, can improve cellular immunization and non-specific immunity, suppress humoral immunization, have the function of regulating immunologic balance.
Herba Dendrobii: cold nature, sweet in the mouth is gone into stomach, kidney channel, has reinforcing stomach reg fluid, nourishing YIN and clearing away heat, the effect of lung moistening kidney tonifying is used for consumption of body fluid by heat, low grade fever excessive thirst, the few tongue of red tongue; Deficiency of stomach-Yin, thirsty and dry pharynx, vomiting is eaten less, vague epigastralgia, the few tongue of tongue light; Deficiency of kidney yin, cards such as blurring of vision.
Fructus Toosendan: cold in nature, bitter in the mouth is returned liver, stomach, small intestinal, urinary bladder channel, has soothing the liver expelling the heat-evil, promoting the circulation of QI to relieve pain, and the effect of parasite killing cures mainly side of body rib abdominal distention, hernia pain, abdominal pain due to worm stagnation, stranguria pain in the penis, tinea capitis, cards such as urticaria.
The ratio of weight and number of each component in the described Chinese medicine is Fructus Crataegi 15～25 weight portions, Herba Plantaginis 15～25 weight portions, Thallus Laminariae (Thallus Eckloniae) 70～80 weight portions, Flos Inulae 20～30 weight portions, Bulbus Fritillariae Cirrhosae 20～30 weight portions, Radix Et Rhizoma Rhei 25～35 weight portions, Rhizoma Curcumae 30～40 weight portions, Ramulus Uncariae Cum Uncis 70～80 weight portions, Fructus Schisandrae Chinensis 10～20 weight portions, Pollen Typhae 30～40 weight portions, Fructus Forsythiae 20～30 weight portions, Folium Nelumbinis 20～30 weight portions, Herba Taxilli 20～30 weight portions, Herba Leonuri 30～40 weight portions, Crinis Carbonisatus 30～40 weight portions, Aloe 15～25 weight portions, Herba Cistanches 10～20 weight portions, Radix Knoxiae 15～25 weight portions, Rhizoma Zingiberis 15～25 weight portions, Cortex Cinnamomi 15～25 weight portions, the Radix Astragali 35～45 weight portions, Rhizoma Polygonati 35～45 weight portions, Radix Adenophorae 20～30 weight portions, Herba Dendrobii 20～30 weight portions and Fructus Toosendan 10～20 weight portions.
The ratio of weight and number of each component in the described Chinese medicine is Fructus Crataegi 20～25 weight portions more preferably, Herba Plantaginis 20～25 weight portions, Thallus Laminariae (Thallus Eckloniae) 75～80 weight portions, Flos Inulae 25～30 weight portions, Bulbus Fritillariae Cirrhosae 25～30 weight portions, Radix Et Rhizoma Rhei 30～35 weight portions, Rhizoma Curcumae 35～40 weight portions, Ramulus Uncariae Cum Uncis 75～80 weight portions, Fructus Schisandrae Chinensis 15～20 weight portions, Pollen Typhae 35～40 weight portions, Fructus Forsythiae 25～30 weight portions, Folium Nelumbinis 25～30 weight portions, Herba Taxilli 25～30 weight portions, Herba Leonuri 35～40 weight portions, Crinis Carbonisatus 35～40 weight portions, Aloe 20～25 weight portions, Herba Cistanches 15～20 weight portions, Radix Knoxiae 20～25 weight portions, Rhizoma Zingiberis 20～25 weight portions, Cortex Cinnamomi 20～25 weight portions, the Radix Astragali 40～45 weight portions, Rhizoma Polygonati 40～45 weight portions, Radix Adenophorae 25～30 weight portions, Herba Dendrobii 25～30 weight portions and Fructus Toosendan 15～20 weight portions.
The ratio of weight and number of each component in the described Chinese medicine is Fructus Crataegi 22 weight portions more preferably, Herba Plantaginis 22 weight portions, Thallus Laminariae (Thallus Eckloniae) 78 weight portions, Flos Inulae 28 weight portions, Bulbus Fritillariae Cirrhosae 28 weight portions, Radix Et Rhizoma Rhei 32 weight portions, Rhizoma Curcumae 38 weight portions, Ramulus Uncariae Cum Uncis 78 weight portions, Fructus Schisandrae Chinensis 18 weight portions, Pollen Typhae 38 weight portions, Fructus Forsythiae 28 weight portions, Folium Nelumbinis 28 weight portions, Herba Taxilli 28 weight portions, Herba Leonuri 38 weight portions, Crinis Carbonisatus 38 weight portions, Aloe 22 weight portions, Herba Cistanches 18 weight portions, Radix Knoxiae 22 weight portions, Rhizoma Zingiberis 22 weight portions, Cortex Cinnamomi 22 weight portions, the Radix Astragali 42 weight portions, Rhizoma Polygonati 42 weight portions, Radix Adenophorae 28 weight portions, Herba Dendrobii 28 weight portions and Fructus Toosendan 18 weight portions.
The present invention also provides above-mentioned preparation method of Chinese medicine, and when the dosage form of described Chinese medicine was tablet, it may further comprise the steps,
The first step, described component is pressed described mixed, add the deionized water with respect to 3～6 times of described mixture qualities, decocted 2～4 hours, filter, in the filtering residue that obtains, further add the deionized water with respect to 0.5～1 times of described mixture quality, decocted again 1～2 hour, and filtered, with the filtrate mixing of twice acquisition, carry out concentrating under reduced pressure, relative density is 1.29～1.32 mastic when being concentrated into temperature and being 70 ℃;
Second step, in the mastic that the first step obtains, add determining alcohol with respect to 3～5 times of mastic quality and be 85%～95% ethanol, stirring and dissolving obtains alcoholic solution, alcoholic solution was left standstill 24～36 hours under 5 ℃～10 ℃ condition, adopt percolation with the speed of per minute 1～2ml percolation slowly, collect percolate, concentrate and drying, be ground into powder;
The 3rd step was ground into 50 order to 100 purpose fine powders with the powder that obtains, and with respect to the starch of 0.3～0.6 times of the quality of the fine powder that obtains, mix homogeneously is granulated subsequently, drying, and tabletting makes tablet.
The present invention also provides above-mentioned preparation method of Chinese medicine, and when described form of Chinese drug was drop pill, it may further comprise the steps,
The first step, described component is pressed described mixed, add the deionized water with respect to 3～6 times of described mixture qualities, decocted 2～4 hours, filter, in the filtering residue that obtains, further add the deionized water with respect to 0.5～1 times of described mixture quality, decocted again 1～2 hour, and filtered, with the filtrate mixing of twice acquisition, carry out concentrating under reduced pressure, relative density is 1.29～1.32 mastic when being concentrated into temperature and being 70 ℃;
Second step, in the mastic that the first step obtains, add determining alcohol with respect to 3～5 times of mastic quality and be 85%～95% ethanol, stirring and dissolving obtains alcoholic solution, alcoholic solution was left standstill 24～36 hours under 5 ℃～10 ℃ condition, adopt percolation with the speed of per minute 1～2ml percolation slowly, collect percolate, concentrate and drying, be ground into powder;
The 3rd step, get the powder of second step acquisition of 100 weight portions, the Macrogol 4000 of 100～200 weight portions, the methyl-silicone oil of 5～10 weight portions, powder is added water make even pasty state, add the Macrogol 4000 substrate liquid that dissolves again, heating and melting becomes supernatant liquid, pour in the drop pill device of preheating, temperature processed and speed are dripped in control, splash in the methyl-silicone oil condensed fluid, blot condensed fluid after becoming ball, collect drop pill, put in the exsiccator, namely get drop pill.
The present invention also provides above-mentioned preparation method of Chinese medicine, and when the dosage form of described Chinese medicine was electuary, it may further comprise the steps,
The first step, described component is pressed described mixed, add the deionized water with respect to 3～6 times of described mixture qualities, decocted 2～4 hours, filter, in the filtering residue that obtains, further add the deionized water with respect to 0.5～1 times of described mixture quality, decocted again 1～2 hour, and filtered, with the filtrate mixing of twice acquisition, carry out concentrating under reduced pressure, relative density is 1.29～1.32 mastic when being concentrated into temperature and being 70 ℃;
Second step, in the mastic that the first step obtains, add determining alcohol with respect to 3～5 times of mastic quality and be 85%～95% ethanol, stirring and dissolving obtains alcoholic solution, alcoholic solution was left standstill 24～36 hours under 5 ℃～10 ℃ condition, adopt percolation with the speed of per minute 1～2ml percolation slowly, collect percolate, concentrate and drying, be ground into powder;
In the 3rd step, with described powder and glucose, sucrose mixing, obtain the electuary finished product; The weight ratio of described powder and described glucose, sucrose is 10: 1～4: 1～6.
Wherein, the dosage form of described Chinese medicine is electuary, tablet or drop pill.
Below adopt embodiment to describe embodiments of the present invention in detail, how the application technology means solve technical problem to the present invention whereby, and the implementation procedure of reaching technique effect can fully understand and implements according to this.
The tablet of embodiment 1 Chinese medicine preparation of the present invention
With Fructus Crataegi 22g, Herba Plantaginis 22g, Thallus Laminariae (Thallus Eckloniae) 78g, Flos Inulae 28g, Bulbus Fritillariae Cirrhosae 28g, Radix Et Rhizoma Rhei 32g, Rhizoma Curcumae 38g, Ramulus Uncariae Cum Uncis 78g, Fructus Schisandrae Chinensis 18g, Pollen Typhae 38g, Fructus Forsythiae 28g, Folium Nelumbinis 28g, Herba Taxilli 28g, Herba Leonuri 38g, Crinis Carbonisatus 38g, Aloe 22g, Herba Cistanches 18g, Radix Knoxiae 22g, Rhizoma Zingiberis 22g, Cortex Cinnamomi 22g, Radix Astragali 42g, Rhizoma Polygonati 42g, Radix Adenophorae 28g, Herba Dendrobii 28g and Fructus Toosendan 18g mix, the deionized water that adds 3400g, decocted 3 hours, filter, the deionized water that in the filtering residue that obtains, further adds 400g, decocted again 2 hours, filter, the filtrate of twice acquisition is mixed, carry out concentrating under reduced pressure, being concentrated into relative density is the mastic of 1.32 (70 ℃); Adding 3300g determining alcohol is 95% ethanol in the mastic that obtains, and stirring and dissolving obtains alcoholic solution, and alcoholic solution was left standstill under 5 ℃ condition 24 hours, adopt percolation with the speed of per minute 1ml percolation slowly, collect percolate, concentrate and drying, be ground into powder; The powder that obtains is ground into 50 purpose fine powders, adds the starch of 320g subsequently, mix homogeneously is granulated, drying, and tabletting makes tablet.
The electuary of embodiment 2 Chinese medicine preparations of the present invention
With Fructus Crataegi 22g, Herba Plantaginis 22g, Thallus Laminariae (Thallus Eckloniae) 78g, Flos Inulae 28g, Bulbus Fritillariae Cirrhosae 28g, Radix Et Rhizoma Rhei 32g, Rhizoma Curcumae 38g, Ramulus Uncariae Cum Uncis 78g, Fructus Schisandrae Chinensis 18g, Pollen Typhae 38g, Fructus Forsythiae 28g, Folium Nelumbinis 28g, Herba Taxilli 28g, Herba Leonuri 38g, Crinis Carbonisatus 38g, Aloe 22g, Herba Cistanches 18g, Radix Knoxiae 22g, Rhizoma Zingiberis 22g, Cortex Cinnamomi 22g, Radix Astragali 42g, Rhizoma Polygonati 42g, Radix Adenophorae 28g, Herba Dendrobii 28g and Fructus Toosendan 18g mix, the deionized water that adds 3400g, decocted 3 hours, filter, the deionized water that in the filtering residue that obtains, further adds 400g, decocted again 2 hours, filter, the filtrate of twice acquisition is mixed, carry out concentrating under reduced pressure, being concentrated into relative density is the mastic of 1.32 (70 ℃); Adding 3300g determining alcohol is 95% ethanol in the mastic that obtains, and stirring and dissolving obtains alcoholic solution, and alcoholic solution was left standstill under 5 ℃ condition 24 hours, adopt percolation with the speed of per minute 1ml percolation slowly, collect percolate, concentrate and drying, be ground into powder; With described powder and 160g glucose, 240g sucrose mixing, obtain the electuary finished product.
The drop pill of embodiment 3 Chinese medicine preparations of the present invention
With Fructus Crataegi 22g, Herba Plantaginis 22g, Thallus Laminariae (Thallus Eckloniae) 78g, Flos Inulae 28g, Bulbus Fritillariae Cirrhosae 28g, Radix Et Rhizoma Rhei 32g, Rhizoma Curcumae 38g, Ramulus Uncariae Cum Uncis 78g, Fructus Schisandrae Chinensis 18g, Pollen Typhae 38g, Fructus Forsythiae 28g, Folium Nelumbinis 28g, Herba Taxilli 28g, Herba Leonuri 38g, Crinis Carbonisatus 38g, Aloe 22g, Herba Cistanches 18g, Radix Knoxiae 22g, Rhizoma Zingiberis 22g, Cortex Cinnamomi 22g, Radix Astragali 42g, Rhizoma Polygonati 42g, Radix Adenophorae 28g, Herba Dendrobii 28g and Fructus Toosendan 18g mix, the deionized water that adds 3400g, decocted 3 hours, filter, the deionized water that in the filtering residue that obtains, further adds 400g, decocted again 2 hours, filter, the filtrate of twice acquisition is mixed, carry out concentrating under reduced pressure, being concentrated into relative density is the mastic of 1.32 (70 ℃); Adding 3300g determining alcohol is 95% ethanol in the mastic that obtains, and stirring and dissolving obtains alcoholic solution, and alcoholic solution was left standstill under 5 ℃ condition 24 hours, adopt percolation with the speed of per minute 1ml percolation slowly, collect percolate, concentrate and drying, be ground into powder; Get the powder of acquisition, the Macrogol 4000 of 1000g, the methyl-silicone oil of 60g, powder is added water make even pasty state, add the Macrogol 4000 substrate liquid that dissolves again, heating and melting becomes supernatant liquid, pours in the drop pill device of preheating, temperature processed and speed are dripped in control, splash in the methyl-silicone oil condensed fluid, blot condensed fluid behind the one-tenth ball, collect drop pill, put in the exsiccator, namely get drop pill.
Clinical experiment
1.1 clinical data
186 routine cases are the outpatient, all have obesity.The Secondary Obesity that eliminating is caused by diseases such as hypothalamus, adrenal gland, hypophysis, thyroid.Male 112 examples wherein, women 74 examples; 24～68 years old age, average 46. 7 years old; Slight fat 41 examples, fat 83 examples of moderate, fat 62 examples of severe; With hyperpietic's 86 examples, coronary disease patient 46 examples, cholecystitis or cholelithiasis person 14 examples, hyperlipemia person's 143 examples; With dizzy person's 83 examples, moving person's cardiopalmus, asthma person's 53 examples, fatigue and asthenia person's 91 examples, hyperhidrosis person's 67 examples that To Be Protected from Heat are detested trencherman's 61 examples, constipation 52 examples.
1.2 Therapeutic Method
The Chinese medicine electuary of the embodiment of the invention 2 preparations, each 50g is dissolved in wet suit usefulness, and every day 3 times, 30 days was 1 course for the treatment of, treated 3 courses for the treatment of, required patient's reasonable diet during the treatment.
1.3 criterion of therapeutical effect
Formulate standard with reference to Chinese combination of Chinese and Western medicine obesity research group third revision: produce effects: during the treatment end more than the weight loss 5kg; Effectively: weight loss 3～5kg when treatment finishes; Invalid: weight loss did not reach above-mentioned standard person when treatment finished.
1.3.2 efficacy result
This experimental group 186 routine obesity patients, produce effects 125 examples, effective 61 examples, invalid patient, body weight average out to 79. 6kg before the treatment are down to 72. 4kg after the treatment, 7. 2kg that on average descend, doing well,improving or disappearance situation see table 1 for details.
Table 1 observation of symptoms table
Grip changes: have 121 examples to measure grip before and after the treatment and change, right-hand man's grip is respectively 19. 2,19. 9kg before the treatment, is respectively 19. 8,20. 6kg after the treatment, illustrates that this medicine in fat-reducing, does not influence muscle power.
Blood Lipid: when reducing body weight, tangible reduction TG, TC are also arranged, the effect of rising HDL-C.See table 2 for details.
Table 2 blood fat is observed table
| Blood fat | Before the treatment | After the treatment |
| TG | 2.92±0.71 | 1.63±0.63 * |
| TC | 8.31±1.21 | 4.73±1.01 * |
| HDL-C | 0.93±0.64 | 1.76±0.31 * |
Annotate: with compare before the treatment
*P＜0. 05.
This intellectual property of primary enforcement that all are above-mentioned is not set restriction this new product of other forms of enforcement and/or new method.Those skilled in the art will utilize this important information, and foregoing is revised, to realize similar implementation status.But all modifications or transformation belong to the right of reservation based on new product of the present invention.
The above only is preferred embodiment of the present invention, is not to be the restriction of the present invention being made other form, and any those skilled in the art may utilize the technology contents of above-mentioned announcement to be changed or be modified as the equivalent embodiment of equivalent variations.But every technical solution of the present invention content that do not break away to any simple modification, equivalent variations and remodeling that above embodiment does, still belongs to the protection domain of technical solution of the present invention according to technical spirit of the present invention.
Claims (1)
- One kind the fat-reducing Chinese medicine, it is characterized in that, by Fructus Crataegi, Herba Plantaginis, Thallus Laminariae (Thallus Eckloniae), Flos Inulae, Bulbus Fritillariae Cirrhosae, Radix Et Rhizoma Rhei, Rhizoma Curcumae, Ramulus Uncariae Cum Uncis, Fructus Schisandrae Chinensis, Pollen Typhae, Fructus Forsythiae, Folium Nelumbinis, Herba Taxilli, Herba Leonuri, Crinis Carbonisatus, Aloe, Herba Cistanches, Radix Knoxiae, Rhizoma Zingiberis, Cortex Cinnamomi, the Radix Astragali, Rhizoma Polygonati, Radix Adenophorae, Herba Dendrobii and Fructus Toosendan are formed, and the ratio of weight and number of each component in the described Chinese medicine is Fructus Crataegi 15～25 weight portions, Herba Plantaginis 15～25 weight portions, Thallus Laminariae (Thallus Eckloniae) 70～80 weight portions, Flos Inulae 20～30 weight portions, Bulbus Fritillariae Cirrhosae 20～30 weight portions, Radix Et Rhizoma Rhei 25～35 weight portions, Rhizoma Curcumae 30～40 weight portions, Ramulus Uncariae Cum Uncis 70～80 weight portions, Fructus Schisandrae Chinensis 10～20 weight portions, Pollen Typhae 30～40 weight portions, Fructus Forsythiae 20～30 weight portions, Folium Nelumbinis 20～30 weight portions, Herba Taxilli 20～30 weight portions, Herba Leonuri 30～40 weight portions, Crinis Carbonisatus 30～40 weight portions, Aloe 15～25 weight portions, Herba Cistanches 10～20 weight portions, Radix Knoxiae 15～25 weight portions, Rhizoma Zingiberis 15～25 weight portions, Cortex Cinnamomi 15～25 weight portions, the Radix Astragali 35～45 weight portions, Rhizoma Polygonati 35～45 weight portions, Radix Adenophorae 20～30 weight portions, Herba Dendrobii 20～30 weight portions and Fructus Toosendan 10～20 weight portions.2. Chinese medicine as claimed in claim 1, it is characterized in that: the dosage form of described Chinese medicine is electuary, tablet or drop pill.3. Chinese medicine as claimed in claim 1, it is characterized in that: the ratio of weight and number of each component in the described Chinese medicine is Fructus Crataegi 20～25 weight portions, Herba Plantaginis 20～25 weight portions, Thallus Laminariae (Thallus Eckloniae) 75～80 weight portions, Flos Inulae 25～30 weight portions, Bulbus Fritillariae Cirrhosae 25～30 weight portions, Radix Et Rhizoma Rhei 30～35 weight portions, Rhizoma Curcumae 35～40 weight portions, Ramulus Uncariae Cum Uncis 75～80 weight portions, Fructus Schisandrae Chinensis 15～20 weight portions, Pollen Typhae 35～40 weight portions, Fructus Forsythiae 25～30 weight portions, Folium Nelumbinis 25～30 weight portions, Herba Taxilli 25～30 weight portions, Herba Leonuri 35～40 weight portions, Crinis Carbonisatus 35～40 weight portions, Aloe 20～25 weight portions, Herba Cistanches 15～20 weight portions, Radix Knoxiae 20～25 weight portions, Rhizoma Zingiberis 20～25 weight portions, Cortex Cinnamomi 20～25 weight portions, the Radix Astragali 40～45 weight portions, Rhizoma Polygonati 40～45 weight portions, Radix Adenophorae 25～30 weight portions, Herba Dendrobii 25～30 weight portions and Fructus Toosendan 15～20 weight portions.4. Chinese medicine as claimed in claim 3, it is characterized in that: the ratio of weight and number of each component in the described Chinese medicine is Fructus Crataegi 22 weight portions, Herba Plantaginis 22 weight portions, Thallus Laminariae (Thallus Eckloniae) 78 weight portions, Flos Inulae 28 weight portions, Bulbus Fritillariae Cirrhosae 28 weight portions, Radix Et Rhizoma Rhei 32 weight portions, Rhizoma Curcumae 38 weight portions, Ramulus Uncariae Cum Uncis 78 weight portions, Fructus Schisandrae Chinensis 18 weight portions, Pollen Typhae 38 weight portions, Fructus Forsythiae 28 weight portions, Folium Nelumbinis 28 weight portions, Herba Taxilli 28 weight portions, Herba Leonuri 38 weight portions, Crinis Carbonisatus 38 weight portions, Aloe 22 weight portions, Herba Cistanches 18 weight portions, Radix Knoxiae 22 weight portions, Rhizoma Zingiberis 22 weight portions, Cortex Cinnamomi 22 weight portions, the Radix Astragali 42 weight portions, Rhizoma Polygonati 42 weight portions, Radix Adenophorae 28 weight portions, Herba Dendrobii 28 weight portions and Fructus Toosendan 18 weight portions.5. preparation method of Chinese medicine as claimed in claim 1 is characterized in that:When the dosage form of described Chinese medicine was tablet, it may further comprise the steps,The first step, described component is pressed described mixed, add the deionized water with respect to 3～6 times of described mixture qualities, decocted 2～4 hours, filter, in the filtering residue that obtains, further add the deionized water with respect to 0.5～1 times of described mixture quality, decocted again 1～2 hour, and filtered, with the filtrate mixing of twice acquisition, carry out concentrating under reduced pressure, relative density is 1.29～1.32 mastic when being concentrated into temperature and being 70 ℃;Second step, in the mastic that the first step obtains, add determining alcohol with respect to 3～5 times of mastic quality and be 85%～95% ethanol, stirring and dissolving obtains alcoholic solution, alcoholic solution was left standstill 24～36 hours under 5 ℃～10 ℃ condition, adopt percolation with the speed of per minute 1～2ml percolation slowly, collect percolate, concentrate and drying, be ground into powder;The 3rd step was ground into 50 order to 100 purpose fine powders with the powder that obtains, and with respect to the starch of 0.3～0.6 times of the quality of the fine powder that obtains, mix homogeneously is granulated subsequently, drying, and tabletting makes tablet.6. preparation method of Chinese medicine as claimed in claim 1 is characterized in that:When described form of Chinese drug was drop pill, it may further comprise the steps,The first step, described component is pressed described mixed, add the deionized water with respect to 3～6 times of described mixture qualities, decocted 2～4 hours, filter, in the filtering residue that obtains, further add the deionized water with respect to 0.5～1 times of described mixture quality, decocted again 1～2 hour, and filtered, with the filtrate mixing of twice acquisition, carry out concentrating under reduced pressure, relative density is 1.29～1.32 mastic when being concentrated into temperature and being 70 ℃;Second step, in the mastic that the first step obtains, add determining alcohol with respect to 3～5 times of mastic quality and be 85%～95% ethanol, stirring and dissolving obtains alcoholic solution, alcoholic solution was left standstill 24～36 hours under 5 ℃～10 ℃ condition, adopt percolation with the speed of per minute 1～2ml percolation slowly, collect percolate, concentrate and drying, be ground into powder;The 3rd step, get the powder of second step acquisition of 100 weight portions, the Macrogol 4000 of 100～200 weight portions, the methyl-silicone oil of 5～10 weight portions, powder is added water make even pasty state, add the Macrogol 4000 substrate liquid that dissolves again, heating and melting becomes supernatant liquid, pour in the drop pill device of preheating, temperature processed and speed are dripped in control, splash in the methyl-silicone oil condensed fluid, blot condensed fluid after becoming ball, collect drop pill, put in the exsiccator, namely get drop pill.7. preparation method of Chinese medicine as claimed in claim 1 is characterized in that:When the dosage form of described Chinese medicine was electuary, it may further comprise the steps,The first step, described component is pressed described mixed, add the deionized water with respect to 3～6 times of described mixture qualities, decocted 2～4 hours, filter, in the filtering residue that obtains, further add the deionized water with respect to 0.5～1 times of described mixture quality, decocted again 1～2 hour, and filtered, with the filtrate mixing of twice acquisition, carry out concentrating under reduced pressure, relative density is 1.29～1.32 mastic when being concentrated into temperature and being 70 ℃;Second step, in the mastic that the first step obtains, add determining alcohol with respect to 3～5 times of mastic quality and be 85%～95% ethanol, stirring and dissolving obtains alcoholic solution, alcoholic solution was left standstill 24～36 hours under 5 ℃～10 ℃ condition, adopt percolation with the speed of per minute 1～2ml percolation slowly, collect percolate, concentrate and drying, be ground into powder;In the 3rd step, with described powder and glucose, sucrose mixing, obtain the electuary finished product; The weight ratio of described powder and described glucose, sucrose is 10: 1～4: 1～6.
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| CN1329893A (en) * | 2000-06-16 | 2002-01-09 | 杨传平 | Chinese medicine for decreasing fat and lossing weight and preparation method thereof |
| CN1824194A (en) * | 2005-12-28 | 2006-08-30 | 王燕红 | Pure Chinese medicine external use body fat reducing medicine |
-
2012
- 2012-03-23 CN CN 201210079594 patent/CN102580048B/en active Active
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1329893A (en) * | 2000-06-16 | 2002-01-09 | 杨传平 | Chinese medicine for decreasing fat and lossing weight and preparation method thereof |
| CN1824194A (en) * | 2005-12-28 | 2006-08-30 | 王燕红 | Pure Chinese medicine external use body fat reducing medicine |
Non-Patent Citations (7)
| Title |
|---|
| 中医药治疗肥胖研究进展;陈艳等;《辽宁中医药大学学报》;20111105;第13卷(第11期);266-268 * |
| 减肥的中药与验方;郭陈辉;《药膳食疗研究》;20011225(第6期);17-18 * |
| 肥胖症的中药治疗;赵进军等;《现代康复》;20010915;第5卷(第9期);18、20 * |
| 董方言.中药片剂、中药滴丸剂、中药颗粒剂.《现代实用中药新剂型新技术》.人民卫生出版社,2001, * |
| 赵进军等.肥胖症的中药治疗.《现代康复》.2001,第5卷(第9期),18、20. |
| 郭陈辉.减肥的中药与验方.《药膳食疗研究》.2001,(第6期),17-18. |
| 陈艳等.中医药治疗肥胖研究进展.《辽宁中医药大学学报》.2011,第13卷(第11期),266-268. |
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| CN102580048A (en) | 2012-07-18 |
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