CN102552641A - Chinese herbal medicine formula for preventing and treating broiler colibacillosis - Google Patents
Chinese herbal medicine formula for preventing and treating broiler colibacillosis Download PDFInfo
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- CN102552641A CN102552641A CN2012100543935A CN201210054393A CN102552641A CN 102552641 A CN102552641 A CN 102552641A CN 2012100543935 A CN2012100543935 A CN 2012100543935A CN 201210054393 A CN201210054393 A CN 201210054393A CN 102552641 A CN102552641 A CN 102552641A
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Abstract
The invention discloses a Chinese herbal medicine formula for preventing and treating broiler colibacillosis, which belongs to the technical field for breeding broilers. The Chinese herbal medicine formula provided by the invention comprises the components as follows: 12-15 g of cptis chinensis, 10-13 g of sanguisorba officinalis, 6-8 g of isatis root, 9-11 g of astragalus mongholicus, 9-11 g of folium isatidis, 9-11 g of aloes, 12-15 g of honeysuckle, 10-12 g of radix scutellariae and 10-12 g of liquorice. The Chinese herbal medicine is weighed according to the formula ratio; the weighed Chinese herbal medicine is decocted and boiled twice through adding water; the decocted liquid and boiled liquid are combined together to be concentrated into aqueous solution; each 1 mL of aqueous solution comprises 1 g of crude drug; and then the aqueous solution is disinfected and filled under a sterile condition. The Chinese herbal medicine formula provided by the invention is capable of improving the immunity and premonition of the broiler, and has no drug tolerance and drug residue. The treating cost for the broiler is reduced; the slaughter weight of the broiler is improved to over 23.8%; and the economic benefit and the social benefit of broiler breeding are improved.
Description
Technical field
The invention belongs to broiler cultural technique field, is a kind of Chinese herbal medicine additive specifically, is used to prevent and treat the broiler colibacillosis.
Background technology
In the prior art for the control of broiler colibacillosis; Generally be to be used alternatingly gentamycin, cephalosporin, three kinds of antibiotic of streptomycin; The consumption that by specification indicates adds in the entry, let chicken at twice (morning, afternoon each once) in 2h, freely drink, drank 3 days in per 10 days.Its shortcoming is to be prone to produce drug resistance, causes weak curative effect; And use the back inevitably to produce drug residue, influence the broiler product quality, jeopardize food safety and human health.
Summary of the invention
The present invention proposes a kind of Chinese herbal medicine formula and is used for preventing and treating the broiler colibacillosis for the medicine that is adopted in the therapeutic modality that solves employed broiler colibacillosis in the prior art is easy to generate the problem of drug resistance and drug residue.
The prescription of Chinese herbal medicine provided by the invention is: Rhizoma Coptidis 12～15 grams, Radix Sanguisorbae 10～13 grams, Radix Isatidis 6～8 grams, the Radix Astragali 9～11 grams, Folium Isatidis 9～11 grams, Aloe 9～11 grams, Flos Lonicerae 12～15 grams, Radix Scutellariae 10～12 grams and Radix Glycyrrhizae 10～12 grams.
Preferably, Chinese herbal medicine formula is: Rhizoma Coptidis 12 grams, Radix Sanguisorbae 10 grams, Radix Isatidis 6 grams, the Radix Astragali 9 grams, Folium Isatidis 9 grams, Aloe 9 grams, Flos Lonicerae 12 grams, Radix Scutellariae 10 grams, Radix Glycyrrhizae 10 grams.
In another preferred embodiment, Chinese herbal medicine formula is: Rhizoma Coptidis 15 grams, Radix Sanguisorbae 13 grams, Radix Isatidis 8 grams, the Radix Astragali 11 grams, Folium Isatidis 11 grams, Aloe 11 grams, Flos Lonicerae 15 grams, Radix Scutellariae 12 grams, Radix Glycyrrhizae 12 grams.
Method for preparing: Chinese herbal medicine is taken by weighing by formula proportion, decocte with water twice, collecting decoction is condensed into the water preparation that every 1mL contains the 1g crude drug, aseptic sterilization fill.
The invention has the advantages that:
(1) immunity and the premunition of raising broiler;
(2) have no drug resistance, drug residue free;
(3) medical expense of reduction broiler;
(4) body weight of delivering for sale of broiler improves more than 23.8%, improves economic benefit and social benefit that broiler is cultured.
The specific embodiment
The present invention provides a kind of Chinese herbal medicine formula of preventing and treating the broiler colibacillosis, and concrete Chinese herbal medicine comprises: Rhizoma Coptidis 12～15 grams, Radix Sanguisorbae 10～13 grams, Radix Isatidis 6～8 grams, the Radix Astragali 9～11 grams, Folium Isatidis 9～11 grams, Aloe 9～11 grams, Flos Lonicerae 12～15 grams, Radix Scutellariae 10～12 grams, Radix Glycyrrhizae 10～12 grams.
Method for preparing: Chinese herbal medicine is taken by weighing by formula proportion, puts into marmite, add water 500ml and soaked 1 hour, decocted 30-40 minute, pour out the first pass medicinal liquid after, add water 300ml again and continue decoction 20-30 minute, pour out medicinal liquid.Merge medicinal liquid twice, be filled into and have in the graduated beaker, on electric furnace, continue heating, in being condensed into every 1mL decocting liquid, contain the water preparation of 1g crude drug,, in superclean bench, carry out fill, sealing medicinal liquid and Packaging Bottle autoclaving.
Embodiment 1:
Choosing Chinese herbal medicine formula is: Rhizoma Coptidis 12 grams, Radix Sanguisorbae 10 grams, Radix Isatidis 6 grams, the Radix Astragali 9 grams, Folium Isatidis 9 grams, Aloe 9 grams, Flos Lonicerae 12 grams, Radix Scutellariae 10 grams, Radix Glycyrrhizae 10 grams.
Chinese herbal medicine is taken by weighing by formula proportion, puts into marmite, add water 500ml and soaked 1 hour, decocted 30-40 minute, pour out the first pass medicinal liquid after, add water 300ml again and continue decoction 20-30 minute, pour out medicinal liquid.Merge medicinal liquid twice, be filled into and have in the graduated beaker, on electric furnace, continue heating, in being condensed into every 1mL decocting liquid (being medicinal liquid), contain the water preparation of 1g crude drug,, in superclean bench, carry out fill, sealing medicinal liquid and Packaging Bottle autoclaving.The Chinese herbal and crude drugs preparations for preparing in 1ml/ only/day ratio add (water yield is confirmed with the daily drink amount by the number of elements of chicken) in the entry, at twice (upper and lower noon each with once) let chicken freely drink, drank in per 9 days 3 days (drinking inactive 2 days 1 day).
Embodiment 2:
Choosing Chinese herbal medicine formula is: Rhizoma Coptidis 15 grams, Radix Sanguisorbae 13 grams, Radix Isatidis 8 grams, the Radix Astragali 11 grams, Folium Isatidis 11 grams, Aloe 11 grams, Flos Lonicerae 15 grams, Radix Scutellariae 12 grams, Radix Glycyrrhizae 12 grams.
Chinese herbal medicine is taken by weighing by formula proportion, put into marmite, add water 500ml and soaked 1 hour; Decocted 30-40 minute, pour out the first pass medicinal liquid after, add water 300ml again and continue to decoct 20-30 minute; Merge twice decocting liquid (also claiming medicinal liquid), be filled into and have in the graduated beaker, on electric furnace, continue heating; The water preparation that in being condensed into every 1mL decocting liquid, contains the 1g crude drug with medicinal liquid and Packaging Bottle autoclaving, carries out fill, sealing in superclean bench.The Chinese herbal and crude drugs preparations for preparing in 1ml/ only/day ratio add (water yield is confirmed with the daily drink amount by the number of elements of chicken) in the entry, at twice (upper and lower noon each with once) let chicken freely drink, drank in per 9 days 3 days (drinking inactive 2 days 1 day).The result shows, uses the broiler of Chinese herbal medicine formula provided by the invention, and immunity and premunition obviously improve, and the body weight of delivering for sale of broiler improves more than 23.8%.
Escherichia coli are adopted plate dilution method to the in vitro tests of the sensitivity of Chinese herbal medicine formula provided by the invention, carry out two groups of tests, and first group is specially:
Get the 1ml original liquid and add the 1st test tube; In the 2nd test tube, add 0.5ml original liquid and 0.5ml normal saline respectively and be diluted to the 4th test tube with coubling dilution; The 5th test tube is no medicine control tube.Pour medicinal liquid in the aseptic plate into respectively earlier, 60 ℃ of aseptic ordinary nutrient agars of back impouring or maconkey agar, and rapid mix homogeneously are processed flat board.Dip in aseptic spreading rod and to get test and evenly coat planar surface with antibacterial, put cultivate 24h in 37 ℃ of incubators after, observe also record result.
Second group is specially: add the 8ml original liquid at the 1st test tube; The 2nd test tube adds the 4ml original liquid; The 3rd test tube adds the 2ml original liquid; The 4th test tube adds the 1ml original liquid, and the 5th test tube is no medicine control tube, in 5 test tubes of the 2nd test tube to the, adds 4ml, 6ml, 7ml and 8ml normal saline respectively; Adopt and process flat board, behind the cultivation 24h, observe and the record result in the incubator that the coating antibacterial is rearmounted 37 ℃ with first group of identical mode.
Escherichia coli are adopted paper disk method to the sensitivity tests of Chinese herbal medicine formula provided by the invention, have obvious inhibiting compound recipe, single medicinal material preparation to process drug sensitive test paper respectively with what filter out to escherichia coli, measure the size of inhibition zone.Method: cut-off directly soaks 40min for the sterilization filter paper of 0.6cm in original liquid, takes out subsequent use.In the flat board that has prepared, drug sensitive test paper is placed by the sterile working, and every kind of medicine pastes 6, then flat board is put the size of measuring inhibition zone in 37 ℃ of incubators behind the cultivation 24h, gets its meansigma methods.
Measure it to colibacillary bacteriostasis with having obvious inhibiting Chinese herbal medicine to use paper disk method to colibacillary growth in the flat band method bacteriostatic test, the result sees table 1.
Table 19 kind of Chinese herbal medicine is to colibacillary antibacterial result
Thus it is clear that, escherichia coli are all had inhibitory action in various degree through 9 kinds of Chinese herbal medicine (single, compound recipe) that plate dilution method filtered out.Therefore, when carrying out the paper disk method drug sensitive test, all there is inhibition zone to occur with these 9 kinds of Chinese medicines.Can find out from the result; Under high concentration (the 1.0g crude drug/L); Rhizoma Coptidis, Radix Scutellariae, Radix Glycyrrhizae, Radix Isatidis, Aloe, Radix Sanguisorbae, the Radix Astragali, Folium Isatidis, Flos Lonicerae decoction liquor all have tangible bacteriostasis; Relevant with the concentration of antibacterial Chinese herbal medicine on the one hand, on the other hand, colibacillary quantity of coating and mode are also influential on flat board.
Carry out effect test at the broiler jumpbogroup, the test group survival rate is 97.9%, and the matched group survival rate is 98.4%, and difference is not remarkable.Test group is on average delivered body weight 2230g for sale, and matched group is on average delivered body weight 1800g for sale, and test group is higher than matched group significantly.
The Chinese herbal medicine formula that screens among the present invention has antibiotic significantly, antivirus action; Can improve the immunity and the premunition of broiler; The effect of dual function obviously is superior to single antibiotic; Have no drug resistance and nuisanceless incomparable especially characteristics and advantage, reduced medical expense, improved economic benefit and social benefit that broiler is cultured.
Claims (4)
1. prevent and treat the Chinese herbal medicine formula of broiler colibacillosis, it is characterized in that: the prescription of Chinese herbal medicine is: Rhizoma Coptidis 12～15 restrains, Radix Sanguisorbae 10～13 restrains, Radix Isatidis 6～8 restrains, the Radix Astragali 9～11 restrains, Folium Isatidis 9～11 restrains, Aloe 9～11 restrains, Flos Lonicerae 12～15 restrains, Radix Scutellariae 10～12 restrains and Radix Glycyrrhizae 10～12 restrains.
2. the Chinese herbal medicine formula of control broiler colibacillosis according to claim 1 is characterized in that: Chinese herbal medicine formula is: Rhizoma Coptidis 12 grams, Radix Sanguisorbae 10 grams, Radix Isatidis 6 grams, the Radix Astragali 9 grams, Folium Isatidis 9 grams, Aloe 9 grams, Flos Lonicerae 12 grams, Radix Scutellariae 10 grams, Radix Glycyrrhizae 10 grams.
3. the Chinese herbal medicine formula of control broiler colibacillosis according to claim 1 is characterized in that: Chinese herbal medicine formula is: Rhizoma Coptidis 15 grams, Radix Sanguisorbae 13 grams, Radix Isatidis 8 grams, the Radix Astragali 11 grams, Folium Isatidis 11 grams, Aloe 11 grams, Flos Lonicerae 15 grams, Radix Scutellariae 12 grams, Radix Glycyrrhizae 12 grams.
4. the method for preparing of the Chinese herbal medicine formula of control broiler colibacillosis is characterized in that: Chinese herbal medicine is taken by weighing by formula proportion, put into marmite; Add water 500ml and soaked 1 hour, decocted 30-40 minute, pour out the first pass medicinal liquid after; Add water 300ml again and continue to decoct 20-30 minute, pour out medicinal liquid; Merge medicinal liquid twice, be filled into and have in the graduated beaker, on electric furnace, continue heating, in being condensed into every 1mL decocting liquid, contain the water preparation of 1g crude drug.
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| CN201210054393.5A CN102552641B (en) | 2012-03-02 | 2012-03-02 | Chinese herbal medicine formula for preventing and treating broiler colibacillosis |
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103156096A (en) * | 2013-04-02 | 2013-06-19 | 陈景河 | Pigeon feed additive |
| CN107296920A (en) * | 2017-06-28 | 2017-10-27 | 普定县陇泉湾养殖有限公司 | A kind of medicine for treating meat rabbit colibacillosis and preparation method thereof |
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| CN101209307A (en) * | 2006-12-25 | 2008-07-02 | 天津市润拓生物技术有限公司 | Chinese medicinal oral liquid with heat-clearing and detoxication, dampness-eliminating and dysentery-stopping efficacy |
| CN101554414A (en) * | 2008-04-09 | 2009-10-14 | 北京大北农动物保健科技有限责任公司 | Traditional Chinese medicine mixture for treating livestock and poultry virosis and preparation method thereof |
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2012
- 2012-03-02 CN CN201210054393.5A patent/CN102552641B/en not_active Expired - Fee Related
Patent Citations (3)
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| CN1781522A (en) * | 2004-11-30 | 2006-06-07 | 王丙尧 | Chinese medicine composition for treating avian flu |
| CN101209307A (en) * | 2006-12-25 | 2008-07-02 | 天津市润拓生物技术有限公司 | Chinese medicinal oral liquid with heat-clearing and detoxication, dampness-eliminating and dysentery-stopping efficacy |
| CN101554414A (en) * | 2008-04-09 | 2009-10-14 | 北京大北农动物保健科技有限责任公司 | Traditional Chinese medicine mixture for treating livestock and poultry virosis and preparation method thereof |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103156096A (en) * | 2013-04-02 | 2013-06-19 | 陈景河 | Pigeon feed additive |
| CN107296920A (en) * | 2017-06-28 | 2017-10-27 | 普定县陇泉湾养殖有限公司 | A kind of medicine for treating meat rabbit colibacillosis and preparation method thereof |
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| CN102552641B (en) | 2014-02-12 |
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