CN102552492B - Traditional Chinese medicinal composition for treating herpes zoster and preparation method thereof - Google Patents
Traditional Chinese medicinal composition for treating herpes zoster and preparation method thereof Download PDFInfo
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Abstract
The invention discloses a traditional Chinese medicinal composition for treating herpes zoster. The traditional Chinese medicinal composition contains the following raw materials of: by weight, 10-30 parts of Scorzonera austriaca Wild, 5-15 parts of cirsium ovalifolium, 5-15 parts of baikal skullcap root, 5-15 parts of radix paeoniae rubrathe, 5-15 parts of licorice, 10-20 parts of akebia stem, 10-20 parts of Plantain seed, 10-20 parts of rheum officinale, 5-15 parts of rhizoma atractylodis, 5-15 parts of bitter orange, 5-15 parts of gentian, 10-20 parts of isatis root, 10-20 parts of gentrin knotweed and 5-15 parts of periostracum cicadae. The traditional Chinese medicinal composition is a proved prescription, has effects of purging liver-gallbladder fire, invigorating spleen, eliminating dampness, relieving the depressed liver, invigorating blood circulation and relieving pain, has a wide drug resource, has no toxic and side effect, can be used to effectively treat herpes zoster, and has a substantial curative effect as well as high success rate. The effective rate of the composition reaches 89.2%.
Description
Technical field
The present invention relates to contain the medicinal preparation that derives from plant material, particularly a kind of Chinese medicine composition for the treatment of herpes zoster and preparation method thereof.
Background technology
Herpes zoster is apt to occur in adult, and season in spring and autumn is common.Sickness rate increased and is remarkable rising with the age.No matter have rash or without rash type, the difficult dormancy of pain is its main feature, and the skin of diseased region, has scorching hot, sensation of pricking, and after a couple of days, eruption type patient sees intensive vesicle, pain surrounding skin is rubescent, diseased region burns as burnt.The General Symptomies such as visible lymphadenectasis that the state of an illness is more serious, heating.The local bunch of bubble that catchments is along the side peripheral nerve zonal distribution of trooping, with obvious neuralgia.People is unique host of varicella zoster virus, and virus enters blood through respiratory mucosa and forms infection, and can hide for a long time in body.While stimulating (as wound, fatigue, malignant tumor or weak etc. after being ill) to cause Abwehrkraft des Koepers to decline when body is subject to certain, latent virus is activated, along copying generation vesicle in the skin in the descending arrival of sensory nerve axon region that this nerve is arranged, get involved nerve is inflamed, necrosis simultaneously, produces neuralgia.Before dermexanthesis, can there be slightly the General Symptomies such as weak, low grade fever, poor appetite, the conscious burning sensation of illing skin or neuralgia, that touches has obvious hyperpathia, continues 1～3 day, can absence of prodrome be also dermexanthesis.Predilection site is followed successively by intercostal nerves, cervical nerves, nervi trigeminus and waist sacral nerves domination region.There is flushing speckle in affected part Chang Shouxian, occurs very soon the pimple of foxtail millet grain to Semen Glycines size, and bunch shape distributes and do not merge, and then becomes rapidly vesicle, and tonic vesicle wall is shinny, limpid vesicle fluid, and periphery is around blush, and between each bunch of vesicle group, skin is normal.Skin lesion is banded along peripheral nerve to be arranged, and mostly occurs in a side of health, is generally no more than median line.Varicella zoster virus is varicella zoster virus (varicella-zoster virus, VZV), this virus primary infection chickenpox (child), recurrent infection herpes zoster (adult).Because virus has neurotropism, after infection, can hide for a long time in the neuron of spinal nerves posterior root ganglion, when lower for the resistance or tired, infection, cat fever, anger is got angry etc., virus can regrow breeding, and move to skin along nerve fiber, make nerve and the skin of being invaded produce fierce inflammation.The feature that erythra generally has one-sided property and distributes by nerve segment, is comprised of the herpes of collection bunch property, and with pain; Age is larger, and neuralgia is heavier.This sick modern medicine is called herpes zoster, the Fel Serpentis skin ulcer that is called among the people, and skirt-roof dragon, flies the titles such as Serpentis.
Herpes zoster belongs to pathogenic cold-damp and by kidney-Yang, is driven outer general in the performance of skin, only there is neuralgia and without (without the rash type) of herpes, belong to that kidney-Yang is unable drives the performance to skin by cold-damp, occur belonging to erythema or blister kidney-Yang pathogenic cold-damp is driven to the performance in epidermis.General patient has slight heating, the symptom such as tired a couple of days before herpes occurs, performance that kidney-Yang starts that Here it is.Herpes zoster heat syndrome patient skin flushing, tonic vesicle wall, sharp ache, with bitter taste in the mouth and dry throat, irritated irritability, yellow urine, large dry stool, red tongue, yellow fur, stringy and rolling pulse.Controlling should purging liver and gallbladder excess-fire.Wet disease patient skin is light red, flaccid vesicle wall, and pain is lighter, poor appetite or abdominal distention, large loose stool, pale tongue, tongue is white thick or greasy in vain, deep-slow pulse.Controlling should spleen invigorating dehumidifying.If the more than person of local pain after herpes zoster disappears belongs to qi depression to blood stasis, control suitable depressed liver-energy dispersing and QI regulating, promoting blood circulation and stopping pain.External application Chinese medicine can be selected clearing heat, releasing toxin, removing swelling or damp eliminating to receive dry liquid medicine according to the state of an illness and decoct external application.No matter which kind of method, the treatment of herpes zoster should be grasped opportunity, and more early treatment effect is better.Often some middle-older patient, after herpes zoster is cleared up and discharged completely, still gnawing pains take no rest, and local skin is excellent but dare not be touched.The body constitution of its pain is that the ganglionic inflammation of getting involved is even downright bad, the degree weight of pain in time between length and erythra be not necessarily consistent.Especially old people, the various functions of body are all going down with advancing age, and impaired nervous tissue repairs also more difficult, therefore be easy to occur post herpetic neuralgia.Particularly body constitution is poor usually, or treats person not in time, and this kind of sustainable several months of pain is even more of a specified duration.
The common therapy Chang Buneng of herpes zoster is completely cured, though herpes remission, but still gnawing pains take no rest.Chinese medicine is one of culture rarity of the Chinese nation, and it has significant curative effect for treatment herpes zoster, and it is in purging liver and gallbladder excess-fire, and spleen invigorating dehumidifies, depressed liver-energy dispersing and QI regulating, and promoting blood circulation and stopping pain aspect effect is remarkable, and medicine source is many from plant extract, has no side effect.Chinese medicine has its unique advantage on treatment herpes zoster.
Summary of the invention
Technical problem to be solved by this invention is, a kind of purging liver and gallbladder excess-fire is provided, spleen invigorating dehumidifying, depressed liver-energy dispersing and QI regulating, promoting blood circulation and stopping pain aspect effect is remarkable, and medicine source extensively, have no side effect, can effectively treat herpes zoster, significant a kind of Chinese medicine composition for the treatment of herpes zoster of its effect and preparation method thereof.
For solving the problems of the technologies described above, the invention provides a kind of Chinese medicine composition for the treatment of herpes zoster, wherein, each crude drug is as follows than configuration according to weight fraction: Radix Scorzonerae austriacae 10-30 part, Elephantopus scaber L. 5-15 part, Radix Scutellariae 5-15 part, Radix Paeoniae Rubra 5-15 part, Radix Glycyrrhizae 5-15 part, Caulis Akebiae 10-20 part, Semen Plantaginis 10-20 part, Radix Et Rhizoma Rhei 10-20 part, Rhizoma Atractylodis 5-15 part, Fructus Aurantii 5-15 part, Radix Gentianae 5-15 part, Radix Isatidis 10-20 part, Rhizoma Polygoni Cuspidati 10-20 part, Periostracum Cicadae 5-15 part.
Or each crude drug is as follows than configuration according to weight fraction: Radix Scorzonerae austriacae 20-30 part, Elephantopus scaber L. 10-15 part, Radix Scutellariae 10-15 part, Radix Paeoniae Rubra 10-15 part, Radix Glycyrrhizae 10-15 part, Caulis Akebiae 15-20 part, Semen Plantaginis 15-20 part, Radix Et Rhizoma Rhei 15-20 part, Rhizoma Atractylodis 10-15 part, Fructus Aurantii 10-15 part, Radix Gentianae 10-15 part, Radix Isatidis 15-20 part, Rhizoma Polygoni Cuspidati 15-20 part, Periostracum Cicadae 10-15 part.
Or each crude drug is as follows than configuration according to weight fraction: Radix Scorzonerae austriacae 10-20 part, Elephantopus scaber L. 5-10 part, Radix Scutellariae 5-10 part, Radix Paeoniae Rubra 5-10 part, Radix Glycyrrhizae 5-10 part, Caulis Akebiae 10-15 part, Semen Plantaginis 10-15 part, Radix Et Rhizoma Rhei 10-15 part, Rhizoma Atractylodis 5-10 part, Fructus Aurantii 5-10 part, Radix Gentianae 5-10 part, Radix Isatidis 10-15 part, Rhizoma Polygoni Cuspidati 10-15 part, Periostracum Cicadae 5-10 part.
Or each crude drug is as follows than configuration according to weight fraction: Radix Scorzonerae austriacae 15-25 part, Elephantopus scaber L. 8-12 part, Radix Scutellariae 8-12 part, Radix Paeoniae Rubra 8-12 part, Radix Glycyrrhizae 8-12 part, Caulis Akebiae 12-16 part, Semen Plantaginis 12-16 part, Radix Et Rhizoma Rhei 12-16 part, Rhizoma Atractylodis 8-12 part, Fructus Aurantii 8-12 part, Radix Gentianae 8-12 part, Radix Isatidis 12-16 part, Rhizoma Polygoni Cuspidati 12-16 part, Periostracum Cicadae 8-12 part.
Chinese medicine composition of the present invention when use is decocted decoction and is taken, 1 dose of every day, clothes at twice, every 7 days is a course for the treatment of.
The dosage form of Chinese medicine composition of the present invention is: honey refining pill, hydration pill, capsule, oral liquid, tablet, drop pill or syrup.
Object to better implement the present invention, the present invention also provides a kind of preparation method of Chinese medicine composition for the treatment of herpes zoster, and wherein, when the dosage form of Chinese medicine composition is honey refining pill, its preparation method is:
Described each crude drug is soaked 30 minutes to 1 hour, and heated and boiled 30 minutes, filters filtrate for later use; Filtering residue adds water, and heating, boils 30 minutes for the second time, refilters filtrate for later use; Filtering residue adds water again, and heated and boiled 40 minutes is for the third time filtered; Three filtrates are combined, and heating is concentrated into pasty state, puts into baking oven, is controlled at 80 ℃, cooling after drying, and mixes and is twisted into slice with Mel, makes honey refining ball wax seal packing.
When the dosage form of Chinese medicine composition is capsule, its preparation method is:
Described crude drug is added to the ethanol of 10 times of amounts of weight, heating and refluxing extraction 3 times, each 2 hours, 3 extracting solution are merged, decompression recycling ethanol, and to be concentrated into liquor strength be 0.5g crude drug/mL, after sucking filtration, when the relative density of filtrate is 20 ℃ 1.08; The adsorption resin column that described filtrate flow is 10L through volume, uses deionized water or the distilled water eluting of 10 times of resin column volumes afterwards, then uses 95% ethanol elution of 5 times of resin column volumes, collect ethanol elution, remove alcohol solvent, obtain component medicated powder, incapsulate and be made as capsule.
When the dosage form of Chinese medicine composition is tablet, its preparation method is:
Described each crude drug chopping is joined in multi-function extractor, and adding ratio of weight and number is the water soaking 30～40 minutes of 3000 parts, decocts after 1.5 hours, takes out that decoction liquor is standby for the first time; It is that the decocting of 3000 parts boiled after 1 hour that medicinal residues add ratio of weight and number, take out decoction liquor for the second time, aforementioned twice decoction liquor merged and filtered, it is the solution of 1000 parts that filtrate decompression is concentrated into ratio of weight and number, staticly settle 24～36 hours, draw supernatant, add starch after being heated to 40～50 ℃, heating is concentrated into pasty state, put into baking oven, be controlled at 80 ℃, cooling after drying, film-making, dry, molding, subpackage.
Chinese medicine composition of the present invention, eliminating pathogen in the liver gallbladder excess-fire, spleen invigorating dehumidifying, depressed liver-energy dispersing and QI regulating, promoting blood circulation and stopping pain, and medicine source extensively, have no side effect, can effectively treat herpes zoster and pain symptom thereof, therapeutic effect is remarkable, success rate is high, effective percentage reaches 89.2%.
The specific embodiment
The invention discloses a kind of Chinese medicine composition for the treatment of herpes zoster, wherein, each crude drug is as follows than configuration according to weight fraction: Radix Scorzonerae austriacae 10-30 part, Elephantopus scaber L. 5-15 part, Radix Scutellariae 5-15 part, Radix Paeoniae Rubra 5-15 part, Radix Glycyrrhizae 5-15 part, Caulis Akebiae 10-20 part, Semen Plantaginis 10-20 part, Radix Et Rhizoma Rhei 10-20 part, Rhizoma Atractylodis 5-15 part, Fructus Aurantii 5-15 part, Radix Gentianae 5-15 part, Radix Isatidis 10-20 part, Rhizoma Polygoni Cuspidati 10-20 part, Periostracum Cicadae 5-15 part.
Or each crude drug is as follows than configuration according to weight fraction: Radix Scorzonerae austriacae 20-30 part, Elephantopus scaber L. 10-15 part, Radix Scutellariae 10-15 part, Radix Paeoniae Rubra 10-15 part, Radix Glycyrrhizae 10-15 part, Caulis Akebiae 15-20 part, Semen Plantaginis 15-20 part, Radix Et Rhizoma Rhei 15-20 part, Rhizoma Atractylodis 10-15 part, Fructus Aurantii 10-15 part, Radix Gentianae 10-15 part, Radix Isatidis 15-20 part, Rhizoma Polygoni Cuspidati 15-20 part, Periostracum Cicadae 10-15 part.
Or each crude drug is as follows than configuration according to weight fraction: Radix Scorzonerae austriacae 10-20 part, Elephantopus scaber L. 5-10 part, Radix Scutellariae 5-10 part, Radix Paeoniae Rubra 5-10 part, Radix Glycyrrhizae 5-10 part, Caulis Akebiae 10-15 part, Semen Plantaginis 10-15 part, Radix Et Rhizoma Rhei 10-15 part, Rhizoma Atractylodis 5-10 part, Fructus Aurantii 5-10 part, Radix Gentianae 5-10 part, Radix Isatidis 10-15 part, Rhizoma Polygoni Cuspidati 10-15 part, Periostracum Cicadae 5-10 part.
Or each crude drug is as follows than configuration according to weight fraction: Radix Scorzonerae austriacae 15-25 part, Elephantopus scaber L. 8-12 part, Radix Scutellariae 8-12 part, Radix Paeoniae Rubra 8-12 part, Radix Glycyrrhizae 8-12 part, Caulis Akebiae 12-16 part, Semen Plantaginis 12-16 part, Radix Et Rhizoma Rhei 12-16 part, Rhizoma Atractylodis 8-12 part, Fructus Aurantii 8-12 part, Radix Gentianae 8-12 part, Radix Isatidis 12-16 part, Rhizoma Polygoni Cuspidati 12-16 part, Periostracum Cicadae 8-12 part.
When Chinese medicine composition of the present invention is decocted in use decoction and is taken, 1 dose of every day, clothes at twice, every 7 days is a course for the treatment of.
The dosage form of Chinese medicine composition of the present invention is: honey refining pill, hydration pill, capsule, oral liquid, tablet, drop pill or syrup.
Each composition in the present invention:
Radix Scorzonerae austriacae, hardship, cold.For heat-clearing and toxic substances removing, promoting blood circulation and detumescence.Furuncle is controlled in external, carbuncle, venom, mosquito bite, mastitis etc.Subduing swelling and detoxicating.Main infirmities and diseases; Furuncle carbuncle.< < Jiangsu medical material will > >: subduing swelling and detoxicating.Control infirmities and diseases, furuncle carbuncle.< < Ningxia Chinese herbal medicine handbook > >: micro-hardship, cold.
Elephantopus scaber L., performance: cold in nature, bitter in the mouth is pungent; Heat-clearing and toxic substances removing, removing heat from blood detumescence, cough-relieving diuresis.For heat-clearing and toxic substances removing, inducing diuresis to remove edema.For flu, acute tonsillitis, pharyngolaryngitis, eye conjunctivitis, epidemic encephalitis type B, pertussis, acute icterohepatitis, cirrhotic ascites, acute and chronic nephritis, furuncle and phyma, eczema.
Radix Scutellariae, can control pestilence heating, cough due to lung-heat, jaundice due to damp-heat, and the diseases such as dysentery, frequent fetal movement, and have the effects such as antibacterial, antipyretic, blood pressure lowering, the clear pestilence of pathogenic fire purging.
Radix Paeoniae Rubra, hardship, is slightly cold.Return Liver Channel.Clearing away heat and cooling blood, eliminating stasis to stop pain.For maculae caused by violent heat pathogen, hematemesis and epistaxis, conjunctival congestion and swelling pain, hypochondriac pain due to stagnation of liverQI, amenorrhea dysmenorrhea, lump in the abdomen stomachache, injury from falling down, carbuncle skin infection.< < herbal classic > >: " bitter in the mouth, flat." < < WU Pu Bencao > >: " paulownia monarch: sweet, nontoxic.Discrimination primary: salty.Li Shi: Slight Cold.Thunder God: acid." < < do not record > >: " and acid, flat being slightly cold, slightly poisonous." < < Amplification on Materia Medica > >: " puckery hardship." enter liver, spleen channel.
Radix Glycyrrhizae, property is flat, and sweet in the mouth, returns 12 warps.Have removing toxic substances, eliminate the phlegm, pain relieving, spasmolytic be so that the pharmacological action such as anticancer.In the traditional Chinese medical science, mediation hundred medicines. invigorating the spleen and replenishing QI, heat-clearing and toxic substances removing, expelling phlegm for arresting cough, relieving spasm to stop pain, coordinating the actions of various ingredients in a prescription.For weakness of the spleen and stomach, fatigue and weakness, shortness of breath and palpitation, cough with copious phlegm, gastral cavity abdomen, the anxious pain of extremity contraction, carbuncle sore tumefacting virus, cushion toxicity, strong.< < book on Chinese herbal medicine converges says > >: Radix Glycyrrhizae, and middle QI invigorating, the medicine of tonify deficiency removing toxic substances also.Strengthening the spleen and stomach, Gu the weakness with emaciation of middle gas, association's negative and positive, and uncomfortable battalion defends.Therefore control strain internal injury, deficiency-weakness of spleen-QI, first YANG deficiency, the lung qi void that declines, its Gan Wenping mends, and effect and ginseng, stilbene are also also.And for example laryngopharynx swelling and pain, assistant Fructus Aurantii Immaturus, Mus are glued, and can lung heat clearing open pharynx; Sputum cough, Fructus Perillae, two old altogether, can expectorant pleasant.. the newly organized > > of < < book on Chinese herbal medicine: Radix Glycyrrhizae, sweet in the mouth, gas is flat, warm in nature, can rise and can fall, and positive middle-jiao yang, function of the spleen and stomach is also.Nontoxic.Enter the warp of lunar, few the moon, the moon of fainting.
Caulis Akebiae, nature and flavor: bitter, be slightly cold.Gui Jing: enter heart channel, small intestine meridian, urinary bladder channel.Function: clearing away heart-fire, diuresis, the stimulating milk secretion of stimulating the menstrual flow.Cure mainly: for irritable feverish sensation in the chest, sore throat pharyngalgia, dark coloured urine, five types of stranguria, edema, whole body spasm and pain.< < does not record > >: treat spleen subcutaneous ulcer Chang Yumian, the vexed sound of vomiting, goes out speech, treat deafly, the loose all knots of carbuncle do not disappear, and incised wound, malignant boil, Mus Wei, Wei Zhe, Weng nasal polyp, induced abortion, goes three worms.
Semen Plantaginis, sweet, cold.< < herbal classic > >: main stranguria due to disorder of QI, pain relieving, dredging water passages urine, except arthralgia chiefly caused by damp pathogen.< < Shandong Chinese medicine > >: apply eczema, impetigo, children's's head sore.The < < property of medicine > > that falls: can remove pathogenic wind toxic, the liver affected by pathogenic wind heat, malicious wind dotting punch order, swelling pain is hidden from view, and headache lacrimation, removes irritable feverish sensation of chest and heart.
Radix Et Rhizoma Rhei, nature and flavor: hardship, cold.Gui Jing: stomach warp; Large intestine channel; Liver Channel; Spleen channel.Effect: attack stagnant; Clearing away damp-heat; Pathogenic fire purging; Removing heat from blood; Blood stasis dispelling; Removing toxic substances.Cure mainly: excess-heat constipation; The accumulation of heat feeling of stuffiness in chest; Damp-heat dysentery; Jaundice; Gonorrhea; Edema abdominal distention; Dysuria; Conjunctival congestion; Laryngopharynx swelling and pain; Aphtha of the mouth and tongue; Gastropyretic vomiting; Spit blood; Spitting of blood; Epistaxis; Have blood in stool; Hematuria; Blood-retention; Amenorrhea; The stagnant stomachache of the stasis of blood in puerperal; Lump in the abdomen; Traumatic injury; Pyretic toxicity carbuncle and ulcer; Erysipelas; Scald.Purging heat and dredging bowels, removing pathogenic heat from blood and toxic substance from the body, eliminating blood stasis and inducing menstruation.For excess-heat constipation, stagnant stomachache, dysentery is not well, jaundice due to damp-heat, heat in blood is told nosebleed, conjunctival congestion, pharyngeal swelling, abdominalgia with intestinal abscess, carbuncle furuncle, blood stasis amenorrhea, traumatic injury, external treatment burn due to hot liquid or fire; Upper gastrointestinal hemorrhage.Radix et Rhizoma Rhei (stir-fried with wine) is apt to clear part of the body cavity above the diaphragm housing the heart and lungs noxious heat in the blood system.For conjunctival congestion pharyngeal swelling, gingivitis.Radix Et Rhizoma Rhei rushes down exerts oneself to delay, eliminating fire and detoxication.For pathogenic fire,toxin and furuncles.The hemostasis of charred Radix Et Rhizoma Rhei cooling blood and removing stasis.For heat in blood, there is stasis of blood bleeder.
Rhizoma Atractylodis, pungent, bitter, temperature.Return spleen, stomach, Liver Channel.Drying damp and strengthening spleen, expelling wind and cold, improving eyesight.For distension and fullness in the abdomen, the edema of having loose bowels, beriberi flaccidity of feet with lamenness, rheumatic arthralgia, anemofrigid cold, nyctalopia.
Fructus Aurantii, nature and flavor hardship; Acid; Cold nature is returned through lung; Spleen; Liver; Stomach; Large intestine channel function cures mainly: septum pectorale feeling of fullness; Distending pain over the hypochondrium; Accumulation of food in the stomach and intes tine due to indigestion; Distension and fullness in the abdomen; Heavy after dysentery; Proctoptosis; Uterine prolapse.Controlling rubella itches incessantly.
Radix Gentianae, has the effect of heat clearing away, eliminating pathogen in the liver, arresting convulsion.< < Compendium of Materia Medica > > records: " nature and flavor hardship, puckery, Great Cold, nontoxic.Cure mainly cold and heat between bone, frightened pathogenic factor gas, the wound absolutely that continues, determines the five internal organs, parasite killing poison.". < < Japan hanako materia medica > >: control infantile convulsive seizure due to fright, infantile malnutrition mansion gas, calentura delirium, skin ulcer scabies, improving eyesight, only tired.
Radix Isatidis, has antibiosis and antiviral functions and Detoxication.< < book on Chinese herbal medicine is stated > >: hardship, and cold, nontoxic.Heat clearing away, removing toxic substances, removing heat from blood, sore-throat relieving.Cure mainly: maculae caused by violent heat pathogen; High heat headache; Major part pestilence; Crimson tongue is purple dark, scarlet fever; Erysipelas; Mumps; Sore throat; Skin ulcer is swollen, carbuncle; Chickenpox; Measles; Hepatitis; Influenza, epidemic encephalitis, encephalitis b, pneumonia, coma is told nosebleed, pharyngeal swelling, acute catarrhal conjunctivitis, skin ulcer rash; Can prevent and treat epidemic encephalitis type B, acute, chronic hepatitis, mumps, osteomyelitis.
Rhizoma Polygoni Cuspidati, micro-hardship, is slightly cold.Return liver, gallbladder, lung meridian.Function with cure mainly: heat-clearing and toxic substances removing, promoting the function of the gallbladder to alleviate jaundice, expelling wind and removing dampness, dissipating blood stasis analgesic therapy, relieving cough and resolving phlegm.For arthralgia, jaundice due to damp-heat, amenorrhea ， WEIJIA, cough with copious phlegm, burn due to hot liquid or fire, injury from falling down, carbuncle sore tumefacting virus.
Periostracum Cicadae: sweet, cold.Return lung, Liver Channel.Function: loose wind heat extraction, sore-throat relieving, rash, nebula removing, spasmolytic.For anemopyretic cold, pharyngalgia, hoarseness, measles without adequate eruption, rubella pruritus, conjunctival congestion cataracta, convulsion with spasms, tetanus.
In preparation method:
The dosage form of Chinese medicine composition of the present invention is honey refining pill, and its preparation method is:
Described each crude drug is soaked 30 minutes to 1 hour, and heated and boiled 30 minutes, filters filtrate for later use; Filtering residue adds water, and heating, boils 30 minutes for the second time, refilters filtrate for later use; Filtering residue adds water again, and heated and boiled 40 minutes is for the third time filtered; Three filtrates are combined, and heating is concentrated into pasty state, puts into baking oven, is controlled at 80 ℃, cooling after drying, and mixes and is twisted into slice with Mel, makes honey refining ball wax seal packing.
The dosage form of Chinese medicine composition of the present invention is capsule, and its preparation method is:
Described crude drug is added to the ethanol of 10 times of amounts of weight, heating and refluxing extraction 3 times, each 2 hours, 3 extracting solution are merged, decompression recycling ethanol, and to be concentrated into liquor strength be 0.5g crude drug/mL, after sucking filtration, when the relative density of filtrate is 20 ℃ 1.08; The adsorption resin column that described filtrate flow is 10L through volume, uses deionized water or the distilled water eluting of 10 times of resin column volumes afterwards, then uses 95% ethanol elution of 5 times of resin column volumes, collect ethanol elution, remove alcohol solvent, obtain component medicated powder, incapsulate and be made as capsule.
The dosage form of Chinese medicine composition of the present invention is tablet, and its preparation method is:
Described each crude drug chopping is joined in multi-function extractor, and adding ratio of weight and number is the water soaking 30～40 minutes of 3000 parts, decocts after 1.5 hours, takes out that decoction liquor is standby for the first time; It is that the decocting of 3000 parts boiled after 1 hour that medicinal residues add ratio of weight and number, take out decoction liquor for the second time, aforementioned twice decoction liquor merged and filtered, it is the solution of 1000 parts that filtrate decompression is concentrated into ratio of weight and number, staticly settle 24～36 hours, draw supernatant, add starch after being heated to 40～50 ℃, heating is concentrated into pasty state, put into baking oven, be controlled at 80 ℃, cooling after drying, film-making, dry, molding, subpackage.
Concrete example is as follows
Embodiment 1: Mr. Wang, man, 24 years old.Patient skin is light red gets blister, and bubble wall is lax, broken after erosion ooze out, pain is lighter, thirsty and wish drink not, poor appetite or abdominal distention after meal, large loose stool, pale tongue is fat, deep pulse moderate and slippery pulse.Be Patients with Herpes Zoster after diagnosing, use formula as follows: Radix Scorzonerae austriacae 30g, Elephantopus scaber L. 15g, Radix Scutellariae 15g, Radix Paeoniae Rubra 15g, Radix Glycyrrhizae 15g, Caulis Akebiae 20g, Semen Plantaginis 20g, Radix Et Rhizoma Rhei 20g, Rhizoma Atractylodis 15g, Fructus Aurantii 15g, Radix Gentianae 15g, Radix Isatidis 20g, Rhizoma Polygoni Cuspidati 20g, Periostracum Cicadae 15g.During use, decoct decoction and take, 1 dose of every day, clothes at twice, every 7 days is a course for the treatment of.Take after 2 courses for the treatment of, symptom goes down, and continues to take 1 course for the treatment of, and herpes zoster disappears, and consolidates after curative effect continued to take 1 course for the treatment of and fully recovers, and visits, not recurrence after half a year.
Embodiment 2: Ms Zhang, 39 years old, patient skin flushing, had blister, tonic vesicle wall, scorching hot twinge forms red foxtail millet, and bitter taste in the mouth and dry throat is thirsty, irritated irritability, oliguria with reddish urine, constipation with dry stool, red tongue, yellow and thin fur, deep pulse moderate and slippery pulse.Be Patients with Herpes Zoster after diagnosing, use formula as follows: Radix Scorzonerae austriacae 10g, Elephantopus scaber L. 5g, Radix Scutellariae 5g, Radix Paeoniae Rubra 5g, Radix Glycyrrhizae 5g, Caulis Akebiae 10g, Semen Plantaginis 10g, Radix Et Rhizoma Rhei 10g, Rhizoma Atractylodis 5g, Fructus Aurantii 5g, Radix Gentianae 5g, Radix Isatidis 10g, Rhizoma Polygoni Cuspidati 10g, Periostracum Cicadae 5g.During use, decoct decoction and take, 1 dose of every day, clothes at twice, every 7 days is a course for the treatment of.Take after 3 courses for the treatment of, symptom goes down, and continues to take 1 course for the treatment of, and herpes zoster disappears, and consolidates after curative effect continued to take 1 course for the treatment of and fully recovers, and visits, not recurrence after three months.
Embodiment 3: Mr. Li, 53 years old, patient skin flushing, tonic vesicle wall, has blister, sharp ache, with bitter taste in the mouth and dry throat, irritated irritability, yellow urine, large dry stool, red tongue, yellow fur, stringy and rolling pulse.Be Patients with Herpes Zoster after diagnosing, use formula as follows: Radix Scorzonerae austriacae 15g, Elephantopus scaber L. 8g, Radix Scutellariae 8g, Radix Paeoniae Rubra 8g, Radix Glycyrrhizae 8g, Caulis Akebiae 12g, Semen Plantaginis 12g, Radix Et Rhizoma Rhei 12g, Rhizoma Atractylodis 8g, Fructus Aurantii 8g, Radix Gentianae 8g, Radix Isatidis 12g, Rhizoma Polygoni Cuspidati 12g, Periostracum Cicadae 8g.During use, decoct decoction and take, 1 dose of every day, clothes at twice, every 7 days is a course for the treatment of.Take after 2 courses for the treatment of, symptom goes down, and continues to take 2 courses for the treatment of, and herpes zoster disappears, and consolidates after curative effect continued to take 1 course for the treatment of and fully recovers, and visits, not recurrence after half a year.
Embodiment 4: an auntie, 47 years old, skin was light red, and bleb wall is not obvious, pleurobranch wall local pain is heavier, poor appetite or abdominal distention, large loose stool, pale tongue, tongue is thick in vain, is Patients with Herpes Zoster after diagnosing, uses formula as follows: Radix Scorzonerae austriacae 25g, Elephantopus scaber L. 12g, Radix Scutellariae 12g, Radix Paeoniae Rubra 12g, Radix Glycyrrhizae 12g, Caulis Akebiae 16g, Semen Plantaginis 16g, Radix Et Rhizoma Rhei 16g, Rhizoma Atractylodis 12g, Fructus Aurantii 12g, Radix Gentianae 12g, Radix Isatidis 16g, Rhizoma Polygoni Cuspidati 16g, Periostracum Cicadae 12g.During use, decoct decoction and take, 1 dose of every day, clothes at twice, every 7 days is a course for the treatment of.Take after 2 courses for the treatment of, symptom goes down, and continues to take 1 course for the treatment of, and herpes zoster disappears, and consolidates after curative effect continued to take 1 course for the treatment of and fully recovers, and visits, not recurrence after half a year.
Use the present invention formula, the first half of the year in 2011 accepts for medical treatment in 120 examples, and effective percentage reaches 89.2%.The Chinese medicine composition that the present invention is clear, eliminating pathogen in the liver gallbladder excess-fire, spleen invigorating dehumidifying, depressed liver-energy dispersing and QI regulating, promoting blood circulation and stopping pain, and medicine source extensively, have no side effect, can effectively treat herpes zoster, therapeutic effect is remarkable, success rate is high.
Claims (4)
1. a Chinese medicine composition for the treatment of herpes zoster, is characterized in that, each crude drug is as follows than configuration according to weight fraction: Radix Scorzonerae austriacae 10-30 part, Elephantopus scaber L. 5-15 part, Radix Scutellariae 5-15 part, Radix Paeoniae Rubra 5-15 part, Radix Glycyrrhizae 5-15 part, Caulis Akebiae 10-20 part, Semen Plantaginis 10-20 part, Radix Et Rhizoma Rhei 10-20 part, Rhizoma Atractylodis 5-15 part, Fructus Aurantii 5-15 part, Radix Gentianae 5-15 part, Radix Isatidis 10-20 part, Rhizoma Polygoni Cuspidati 10-20 part, Periostracum Cicadae 5-15 part.
2. the Chinese medicine composition for the treatment of according to claim 1 herpes zoster, is characterized in that, each crude drug is as follows than configuration according to weight fraction: Radix Scorzonerae austriacae 20-30 part, Elephantopus scaber L. 10-15 part, Radix Scutellariae 10-15 part, Radix Paeoniae Rubra 10-15 part, Radix Glycyrrhizae 10-15 part, Caulis Akebiae 15-20 part, Semen Plantaginis 15-20 part, Radix Et Rhizoma Rhei 15-20 part, Rhizoma Atractylodis 10-15 part, Fructus Aurantii 10-15 part, Radix Gentianae 10-15 part, Radix Isatidis 15-20 part, Rhizoma Polygoni Cuspidati 15-20 part, Periostracum Cicadae 10-15 part.
3. the Chinese medicine composition for the treatment of according to claim 1 herpes zoster, is characterized in that, each crude drug is as follows than configuration according to weight fraction: Radix Scorzonerae austriacae 10-20 part, Elephantopus scaber L. 5-10 part, Radix Scutellariae 5-10 part, Radix Paeoniae Rubra 5-10 part, Radix Glycyrrhizae 5-10 part, Caulis Akebiae 10-15 part, Semen Plantaginis 10-15 part, Radix Et Rhizoma Rhei 10-15 part, Rhizoma Atractylodis 5-10 part, Fructus Aurantii 5-10 part, Radix Gentianae 5-10 part, Radix Isatidis 10-15 part, Rhizoma Polygoni Cuspidati 10-15 part, Periostracum Cicadae 5-10 part.
4. the Chinese medicine composition for the treatment of according to claim 1 herpes zoster, is characterized in that, each crude drug is as follows than configuration according to weight fraction: Radix Scorzonerae austriacae 15-25 part, Elephantopus scaber L. 8-12 part, Radix Scutellariae 8-12 part, Radix Paeoniae Rubra 8-12 part, Radix Glycyrrhizae 8-12 part, Caulis Akebiae 12-16 part, Semen Plantaginis 12-16 part, Radix Et Rhizoma Rhei 12-16 part, Rhizoma Atractylodis 8-12 part, Fructus Aurantii 8-12 part, Radix Gentianae 8-12 part, Radix Isatidis 12-16 part, Rhizoma Polygoni Cuspidati 12-16 part, Periostracum Cicadae 8-12 part.
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