CN101332253A

CN101332253A - Traditional Chinese medicine preparation for treating herpes zoster and preparation method thereof

Info

Publication number: CN101332253A
Application number: CNA2008100908459A
Authority: CN
Inventors: 曹青山
Original assignee: Individual
Current assignee: Individual
Priority date: 2008-04-02
Filing date: 2008-04-02
Publication date: 2008-12-31

Abstract

The invention relates to a traditional Chinese medicine external application for curing 'herpes zoster', which belongs to the field of traditional Chinese medicine. According to a principle that the herpes zoster is an acute herpes dermatosis which is initiated by herpes virus caused by the circulation blockage due to damp-heat toxin which then externally appears on the skin, the invention provides an incisive description on the pathology, the pathogeny and the related diseases according to the clinic experiments. The medicine is composed of Ci Meng, pale hindu lotus seedpod, Centipeda minima, phellodendron and borneol which are mixed according to proportions and crushed into granular shapes; the crushed granular materials are then put into a nonmetal and non-chemical container; then industrial distilled water is injected into the container according to proportion for marinating the granular materials; the mixture is decocted with high temperature, filtrated and extracted; the extracted solution is obtained, weighted and blended with the borneol according to proportions; finally the finished medicine can be prepared by high-temperature and slow-fire concentration after being blended. According to the clinic certification, the medicine has the efficacies of safer and faster dehumidification and detoxification, fast curing and recovery, complete disease eradication and no residual verve ache, in addition, the cure rate can reach up to 100 percent.

Description

A kind of Chinese medicine preparation and method for making thereof for the treatment of herpes zoster

Affiliated technical field

The invention belongs to medical domain, particularly a kind of therapeutic activity of Chinese medicine for external application.

Background technology:

Herpes zoster is commonly called as sick title such as Serpentis skirt-roof, herpes zoster, is the difficult viral skin neuropathy that can reach thorough healing in a short time of medical domain.This card morbidity back is produced insufferablely has an intense pain repeatedly, not only seriously hinders patient's orthobiosis, work and study, but also can will cause the threat of death to old or weak patient as can not get effective treatment.

Herpes zoster is by the evil retardance circulation of damp and hot poison, and the acute herpes dermatosis that the herpesvirus due to the outer general skin causes, this disease premorbid has heating, loss of appetite, affected part fever or nerve be symptom such as pain repeatedly, general first day to the 3rd day after ill, the affected part skin can produce irregular erythema, group variety collection papulovesicle appears in affected part then, and comparatively fast be transformed into vesicle as the Semen phaseoli radiati size, the herpes clear is shinny, ordinary circumstance continued to bring out in the 5th day successively at second day, herpes is transformed into muddiness by clear again after several days, the herpes suppuration of breaking then, the withered decrustation in perhaps rotten to the corn back and healing.

Herpes zoster distributes around some nerves, be arranged in band shape, frequently-occurring disease is in a side of body, be no more than the median line of body, but individual patient also has above the body median line, the most of patients morbidity is in positions such as the breast side of body, abdominal part, waist, extremity, face, cervical regions, some old or weak people are suffered from this after being ill, treat timely and effectively if can not get, so local herpes very likely spread the chickenpox sample herpes of general in several days, produce hyperpyrexia then, malignant disease such as concurrent one-tenth such as pneumonia, encephalitis and cause death.

What this virus infraction tegumentary nerve was produced has an intense pain repeatedly, causes patient's uneasy in either sitting or lying all day, lies awake all night lethargy, anorexia.Disappear though some patient sees the herpes of healing, pain is still violent more than repeatedly, and the persistent period is very long, and this is thoroughly not cure left illness.

At medical domain, the traditional Chinese medical science is to Therapeutic Method that herpes zoster adopted combines inside and outside being, its treatment by oral administration of medicines prescription as: " Decoction of Gentiana for Purging the Liver-fire ", " dehumidifying stomach Siberian cocklebur soup " etc., prescription composition majority is made up of Radix Gentianae, Fructus Gardeniae, Caulis Akebiae, Fructus Toosendan, Radix Bupleuri, Herba Portulacae, Rhizoma Corydalis, Polyporus, Cortex Phellodendri etc.And Chinese medicine for external application is as " SANHUANG lotion ", " Herba Taraxaci Herba Violae three yellow stuff " etc.

Doctor trained in Western medicine thinks that herpes zoster is the illness that is caused by acute virus, often adopt for this reason also be inside and outside the treatment measure that combines, antiviral for oral administration and pain relieving Western medicine, the therapeutic modalities such as antiinflammatory and the soak of external Western medicine of also taking simultaneously to infuse, its antiviral Western medicine for oral administration such as valaciclovir, virazole, pain relieving Western medicine such as indomethacin, ibuprofen etc., intravenous drip SHUANGHUANLIAN, cimetidine, acyclovir etc., the treatment of external Western medicine some kinds of medicines such as " phthalein fourth liniments ".

More than 50 personage who suffered from herpes zoster shows through more than ten years investigation and interview successively, because Chinese and western medicine is being suited the medicine to the illness pharmaceutical applications in clinical aspect the treatment herpes zoster, so cause the patient treatment time long, this not only brings long misery to the patient, but also make the patient be subjected to serious wrecking in spirit, also undesirable from the cure rate aspect, part patient is transformed into the chronic tegumentary nerve pain several years and controls and do not heal owing to not thoroughly not curing.

In sum, herpes zoster not only causes the patient to suffer the long but also physical and mental health of seriously wrecking the patient of painful time, from the medication aspect of present medical domain treatment herpes zoster, also do not see and a kind ofly have comparison safety, fast, thoroughly cure the pharmaceutical applications of herpes zoster in clinical.

Summary of the invention:

In order to reach safe and efficient thorough healing herpes zoster on the clinical medicine, free the patient suffering as soon as possible and recover their physical and mental health, the invention provides a kind of Chinese medicine for external application of safe and efficient thorough healing herpes zoster, this external preparation pharmaceutical compositions is few, production cost is low, making is easier to, and is the exterior-applied article of specially controlling herpes zoster.

The present invention is made up of ZIMENG, CANGPENG, Myriogyne minuta, Cortex Phellodendri, Borneolum Syntheticum.

ZIMENG, high-quality CANGPENG, high-quality Myriogyne minuta, high-quality Cortex Phellodendri behind the at first selected White Dew solar term, be mixed in proportion and be broken into graininess, then ground grains shape raw material is encased in nonmetal, non-chemically the clean container, in container, inject industrial distilled water immersion more in proportion, it is fried to pass through high temperature then, filter and extract solution, after the solution that extracts weighed, blend with Borneolum Syntheticum in proportion again, carrying out the high temperature slow fire after blending concentrates, concentrate the back filling and sealing, be Chinese medicine for external application finished product of the present invention.Its technological process is shown in accompanying drawing I.

With following Chinese herbal medicine ZIMENG 6-30%, CANGPENG 5-30%, Myriogyne minuta 1-30%, mix after Cortex Phellodendri 3-15% weighs in proportion and be broken into graininess, be encased in the ground grains raw material nonmetal then, in the container non-chemically, in container, inject industrial distilled water immersion more in proportion, after the soak time expiration, pour into the particulate material and the solution that soak nonmetal, carry out fried in the non-chemically resistant to elevated temperatures container, treat behind fried the finishing that it filters the basic drug solns of extraction when being cooled to below 20 ℃, after basic drug solns after the filtration is weighed, blend with Borneolum Syntheticum 0.2-10% in proportion, drug solns after blending will carry out using instead rapidly after high temperature is fried boiling slow fire and concentrate, after concentrated the reaching quality standards, its finished product preparation is packed into and be sealed in nonmetal, to be packed in the container non-chemically, or direct after cooling fill is in the process washing, sterilization, in the medicinal glass bottle after oven dry is handled, add a cover cellophane film and plug then, reuse aluminum hull sealing back labeling is finished product.

Fig. 1 is a kind of Chinese medicine preparation of herpes zoster and process chart of method for making thereof for the treatment of.

The specific embodiment:

Be illustrated below in conjunction with example.

ZIMENG 6kg behind the selected White Dew solar term selects fine CANGPENG 5kg, high-quality Myriogyne minuta 9kg, high-quality Cortex Phellodendri 3kg, high-quality Borneolum Syntheticum 200g.

Earlier ZIMENG, CANGPENG, Myriogyne minuta, mix after Cortex Phellodendri is weighed in proportion and be broken into graininess, then the ground grains raw material is encased in and holds nonmetal more than the 120kg, in the container non-chemically, sealing is soaked after injecting 100kg industry distilled water in proportion again in container, sealing was soaked 36 hours, temperature remains between 20 ℃ to 26 ℃ between soak period, after the soak time expiration, be poured into the particulate material and the solution that soak nonmetal, carry out fried in the non-chemically resistant to elevated temperatures container, after boiling soaking solution, used slow fire instead fried 120 minutes, when treating that it is cooled to below 20 ℃ behind fried the finishing, filter again and extract basic drug solns, medicinal residues after the filtration are done garbage disposal, after filtering basic drug solns is weighed, blend with the 200g Borneolum Syntheticum in proportion again, use slow fire after drug solns after blending boils with high temperature rapidly instead and concentrate 180 minutes to 210 minutes, reach needed quality standard, be Chinese medicine external finished product preparation of the present invention to impel drug solns.

The finished product preparation that reaches quality standards seals when to be packed, must remain on 5 ℃ to 20 ℃ indoor storage, or directly the volume of fill after handling through washing, high-temperature sterilization, oven dry is in the medicinal glass bottle of 50ml, 100ml, 250ml, add a cover cellophane film and plug then, the sealing of reuse aluminum hull, labeling, packing promptly become the finished product of Chinese medicine for external application of the present invention then.

Preparation of the present invention was successively tested 39 herpes zoster patients' clinical treatment through the more than ten years, never produce any poison and paid effect, and in the treatment practice, verify out that this preparation has the therapeutic efficiency aspect two, and the one, have more safe and efficient removing dampness and detoxicating, cure the fast effect of rehabilitation.Generally eliminate, reach rehabilitation within 8 hours with patient's all pain in 90 minutes of this preparation for treating.The 2nd, have except that disease is engaged in to the greatest extent, the effect of noresidue tegumentary nerve pain.In the past few years by to the personnel that cure of useful preparation pay a return visit the result and be: sequela such as a routine residual tegumentary nerve pain do not take place in all healing persons, and cure rate reaches absolutely, so this preparation is the comparatively ideal medicine of treatment herpes zoster.

Claims

1, a kind of Chinese medicine for external application and method for making thereof for the treatment of herpes zoster, it is made up of four kinds of Chinese herbal medicine and a kind of making up a prescription, and it is characterized in that the prescription proportioning is ZIMENG 6-30%, CANGPENG 5-30%, Myriogyne minuta 1-30%, Cortex Phellodendri 3-15%, Borneolum Syntheticum 0.2-10%; At first with selected ZIMENG, CANGPENG, Myriogyne minuta, Cortex Phellodendri, the back mixing of weighing is broken into graininess, then feed particulate material is encased in can hold nonmetal, non-chemically in the container, sealing is soaked after injecting industrial distilled water in proportion in container again, sealing was soaked 36 hours, after the soak time expiration, pour into the particulate material and the solution that soak nonmetal, carry out fried in the non-chemically resistant to elevated temperatures container, it is fried to use slow fire instead after the solution that soaks boiled, after treating fried finishing, when being cooled to below 20 ℃, it being filtered extract basic drug solns again, after filtering basic drug solns is weighed, blend with Borneolum Syntheticum in proportion again, use slow fire after medicinal liquid after blending boils with high temperature rapidly instead and concentrate, reach required quality standard, be Chinese medicine external finished product preparation of the present invention after reaching quality standards to impel drug solns.

2, a kind of Chinese medicine for external application and method for making thereof for the treatment of herpes zoster according to claim 1 is characterized in that soaking temperature remains between 20 ℃ to 26 ℃.

3, a kind of Chinese medicine for external application and method for making thereof for the treatment of herpes zoster according to claim 1 used slow fire instead fried 120 minutes after it is characterized in that boiling soaking solution.

4, a kind of Chinese medicine for external application and method for making thereof for the treatment of herpes zoster according to claim 1 used slow fire rapidly instead and concentrated 180 minutes to 210 minutes after drug solns after it is characterized in that blending boils with high temperature.