CN102516165A - 取代的吡啶衍生物 - Google Patents

取代的吡啶衍生物 Download PDF

Info

Publication number
CN102516165A
CN102516165A CN2011103097414A CN201110309741A CN102516165A CN 102516165 A CN102516165 A CN 102516165A CN 2011103097414 A CN2011103097414 A CN 2011103097414A CN 201110309741 A CN201110309741 A CN 201110309741A CN 102516165 A CN102516165 A CN 102516165A
Authority
CN
China
Prior art keywords
base
alkene
alkane
alkynes
cycloalkanes
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN2011103097414A
Other languages
English (en)
Chinese (zh)
Inventor
C·W·托诺
N·坎津
M·罗特兰德
W·P·沃森
D·R·格雷弗
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
H Lundbeck AS
Original Assignee
H Lundbeck AS
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by H Lundbeck AS filed Critical H Lundbeck AS
Publication of CN102516165A publication Critical patent/CN102516165A/zh
Pending legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • A61K31/5375—1,4-Oxazines, e.g. morpholine
    • A61K31/5377—1,4-Oxazines, e.g. morpholine not condensed and containing further heterocyclic rings, e.g. timolol

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
CN2011103097414A 2005-03-03 2006-03-02 取代的吡啶衍生物 Pending CN102516165A (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DKPA200500321 2005-03-03
DKPA200500321 2005-03-03

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
CNA2006800068313A Division CN101133053A (zh) 2005-03-03 2006-03-02 取代的吡啶衍生物

Publications (1)

Publication Number Publication Date
CN102516165A true CN102516165A (zh) 2012-06-27

Family

ID=37908541

Family Applications (3)

Application Number Title Priority Date Filing Date
CN2011103097414A Pending CN102516165A (zh) 2005-03-03 2006-03-02 取代的吡啶衍生物
CN201110168073.8A Expired - Fee Related CN102276523B (zh) 2005-03-03 2006-03-02 取代的吡啶衍生物
CNA2006800068313A Pending CN101133053A (zh) 2005-03-03 2006-03-02 取代的吡啶衍生物

Family Applications After (2)

Application Number Title Priority Date Filing Date
CN201110168073.8A Expired - Fee Related CN102276523B (zh) 2005-03-03 2006-03-02 取代的吡啶衍生物
CNA2006800068313A Pending CN101133053A (zh) 2005-03-03 2006-03-02 取代的吡啶衍生物

Country Status (14)

Country Link
KR (2) KR20070108884A (es)
CN (3) CN102516165A (es)
AR (1) AR052931A1 (es)
BR (1) BRPI0608122A2 (es)
DK (1) DK2298766T3 (es)
EA (1) EA016244B1 (es)
ES (1) ES2433593T3 (es)
HK (1) HK1164868A1 (es)
IL (1) IL185113A (es)
NZ (1) NZ556613A (es)
PT (1) PT2298766E (es)
SI (1) SI2298766T1 (es)
UA (1) UA92340C2 (es)
ZA (1) ZA200705987B (es)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN114409593B (zh) * 2022-01-20 2024-02-23 上海泾维化工科技有限公司 一种2-氨基-5-甲基吡啶的制备方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE60037321T4 (de) * 1999-08-04 2010-01-07 Icagen, Inc. Benzanilide als öffner des kaliumkanals
MXPA03000032A (es) * 2000-06-29 2003-08-19 Neurosearch As Uso de derivados de oxindol 3-sustituidos como moduladores de los canales de potasio kcnq.
HUP0303841A2 (hu) * 2001-02-20 2004-03-01 Bristol-Myers Squibb Company 2,4-Diszubsztituált-5-pirimidinkarboxamid-származékok mint KCNQ káliumcsatorna modulátorok és ezeket tartalmazó gyógyszerkészítmények és előállításuk
MXPA05010000A (es) * 2003-03-21 2005-11-17 Lundbeck & Co As H Derivados de p-diaminobenceno substituidos.
TWI349666B (en) * 2004-03-12 2011-10-01 Lundbeck & Co As H Substituted morpholine and thiomorpholine derivatives

Also Published As

Publication number Publication date
EA200701877A1 (ru) 2008-02-28
UA92340C2 (en) 2010-10-25
CN102276523B (zh) 2014-12-10
AR052931A1 (es) 2007-04-11
DK2298766T3 (da) 2013-11-11
ZA200705987B (en) 2009-05-27
ES2433593T3 (es) 2013-12-11
SI2298766T1 (sl) 2014-05-30
CN102276523A (zh) 2011-12-14
IL185113A0 (en) 2007-12-03
BRPI0608122A2 (pt) 2010-11-09
EA016244B1 (ru) 2012-03-30
KR20070108884A (ko) 2007-11-13
NZ556613A (en) 2010-11-26
PT2298766E (pt) 2013-11-07
HK1164868A1 (en) 2012-09-28
CN101133053A (zh) 2008-02-27
KR20130088905A (ko) 2013-08-08
IL185113A (en) 2013-10-31

Similar Documents

Publication Publication Date Title
JP5237643B2 (ja) 置換されたピリジン誘導体
CN102516204A (zh) 取代的吗啉和硫代吗啉衍生物
EP2468732B1 (en) 1H-Quinazoline-2,4-diones
CN105683157B (zh) 用作钠通道调节剂的磺酰胺类
JP4898676B2 (ja) キナゾリン誘導体
US7683058B2 (en) Substituted pyrimidine derivatives
JP2008512402A (ja) 置換されたアニリン誘導体
CN101333192A (zh) 作为钠通道阻滞剂的联芳基取代吡唑
CN101906105B (zh) 吡唑并[1，5-a]嘧啶酮衍生物及其药物组合物以及其用途
TW200927096A (en) Derivatives of 5-amino-4,6-disubstituted indole and 5-amino-4,6-disubstituted indoline as potassium channel modulators
JP2009507052A (ja) ピリミジン誘導体およびそのｋｃｎｑカリウムチャネル開口薬としての使用
JP2003524595A (ja) 薬 剤
CN102276523B (zh) 取代的吡啶衍生物
JP2006500315A (ja) 糖尿病状態に用いるヒスタミン−３受容体リガンド
EP1212054A2 (en) Azetidine compounds in cns and eye diseases
CN100448867C (zh) 用于治疗中枢神经***疾病的1,2,4-三氨基苯衍生物

Legal Events

Date Code Title Description
C06 Publication
PB01 Publication
C10 Entry into substantive examination
SE01 Entry into force of request for substantive examination
REG Reference to a national code

Ref country code: HK

Ref legal event code: DE

Ref document number: 1172339

Country of ref document: HK

C02 Deemed withdrawal of patent application after publication (patent law 2001)
WD01 Invention patent application deemed withdrawn after publication

Application publication date: 20120627

REG Reference to a national code

Ref country code: HK

Ref legal event code: WD

Ref document number: 1172339

Country of ref document: HK