CN102499903B - Oral cavity caring toothpaste composition for children - Google Patents
Oral cavity caring toothpaste composition for children Download PDFInfo
- Publication number
- CN102499903B CN102499903B CN2012100029890A CN201210002989A CN102499903B CN 102499903 B CN102499903 B CN 102499903B CN 2012100029890 A CN2012100029890 A CN 2012100029890A CN 201210002989 A CN201210002989 A CN 201210002989A CN 102499903 B CN102499903 B CN 102499903B
- Authority
- CN
- China
- Prior art keywords
- margarita
- vitamin
- hydrolyzed solution
- weight
- mixture
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
Landscapes
- Cosmetics (AREA)
Abstract
The invention relates to an oral cavity caring toothpaste composition for children. The composition comprises the following raw materials in percentage by weight: 0.01 to 15 percent of nutritional materials, 8 to 30 percent of silicon dioxide hydrate, 40 to 85 percent of humectant, 0.8 to 2 percent of thickening agent, 1 to 3 percent of surfactant, 0.01 to 1 percent of preservative, 0.3 to 3 percent of essences and the balance being deionized water. The toothpaste composition can effectively nourish gum and prevent tooth diseases. Various nutritional components are contained in the toothpaste composition and have the effects of nourishing teeth and gum, caring oral cavity, strengthening gum and firming teeth.
Description
Technical field
The present invention relates to a kind of dentifrice composition and preparation method thereof, especially a kind of dentifrice composition that is applicable to the Pediatric Oral Emergency maintenance, belong to daily necessities field.
Background technology
China oral cleaning nursing article TIA is defined as toothpaste: toothpaste is to be used from cleaning teeth with toothbrush one, a kind of daily necessities of protection oral hygiene to human-body safety.
In daily life; the child is because self lacks self awareness and understanding; often like again eating at ordinary times the snacks such as confection, cookies; and father and mother are not guided well; the oral diseases such as tooth decay, pain appear in a lot of children prematurely, directly have influence on child's study, life and whole body health.So father and mother must teaching children from little attention oral hygiene, the good custom that association forms correctly and brushes teeth, sooner or later brushes teeth.
According to investigations, what most consumers meaned that the child of their family uses is adult's toothpaste, and has 30% people to mean that the child uses adult's toothpaste also passable.According to the toothpaste expert advice, unsuitable for children is used adult's toothpaste, because the safety of adult's toothpaste is not enough to ensure child's health.The p H-number of formulation of tooth-paste of being grown up in the market is higher, reaches 9.5 ~ 9.9, and oral mucosa is had to certain stimulation.And friction is all higher, although easily damage child's tooth of good clean power is arranged.In addition, a lot of mothproof toothpastes are all toothpastes with fluoride.The Investigation on Dental Fluorosis Among Children result shows, the regional prevalence of using toothpaste with fluoride can obviously increase dental fluorosis of high fluoride water.Although toothpaste with fluoride can prevent decayed tooth to a certain extent, toothpaste with fluoride cannot solve the decayed tooth problem fully, and also the child easily swallows toothpaste when brushing teeth, and it is grown the fluorine of child's excess intake and health is very disadvantageous.
Even there is the scholar to investigate discovery; the child uses after toothpaste with fluoride its caries prevalence rate and matched group without significant difference, the factor of suffering from pass with dental caries be brush teeth every day number of times, gargle after the meal, the head of a family to the attitude of oral health, eat a snack before going to bed, mother's schooling, breast feeding situation, happiness eat sweet food, take calcium preparation situation etc.Here it is needs development allow the reason of the higher children's toothpaste of the relieved security performance of the head of a family.
Present children's toothpaste on the market has been noted that the difference of child and adult's oral environment, and children's toothpaste generally all has following characteristics: (1), while brushing teeth, friction does not injure the tender dental surface of child children repeatedly.(2) be aided with in mastic and supplement the required nutrient substance of dental growth.(3) gorgeous color and luster, glittering and translucent lovely outward appearance and fragrant and sweet fruit taste can help child to form good tooth-brushing habit, in a word, and safety, nutrition, gentle mouthfeel and the lovely of outward appearance are the main directions of present children's toothpaste.And children's toothpaste has on the basis of cleaning capacity, also need to there is the nutrition gingiva, the effect of healthy tooth.Therefore particularly important to the selection of nutrient substance in children's toothpaste.
Vitamin C, be again ascorbic acid, is a kind of water soluble vitamins.It is the essential material of collagen protein synthesis.Collagen protein is the key component of intercellular substance, and cell communication is got up in intercellular substance, forms tissue.Equally, collagen protein has also determined microvascular intensity, elasticity in blood vessel, has guaranteed blood vessel intensity, makes blood vessel be not easy to break.Healthy dental bed tightly encases each tooth.Gingiva is soft tissue, and vitamin C can prevent gingival atrophy and hemorrhage.In addition, vitamin C has very strong antioxygenic property, prevents the destruction of radical pair oral cavity tissue, contributes to prevent various oral diseases.
Margarita hydrolyzed solution is by biochemical reaction, decomposition, extraction, and calcium carbonate a large amount of in Margarita powder is removed, and extracts its effective ingredient-several amino acids and other nutritional labelings.These aminoacid comprise 8 kinds of essential amino acids, serine wherein, the scalable human endocrines such as a word used in person's names propylhomoserin, enhancing immunity and remove free radical, antidotal effect.
Summary of the invention
The present invention relates to a kind of oral cavity caring toothpaste composition for children, effectively the nutrition gingiva, prevent that odontopathy from producing.Contain multiple nutritional components in dentifrice composition, nutrition tooth, gingiva are provided, healthy mouth, strong gingiva, the effect of firm tooth.Present technique belongs to the article of everyday use technical field.
A kind of oral cavity caring toothpaste composition for children, described compositions is comprised of following raw materials by weight: 0.01% ~ 15% nutrient substance, 8% ~ 30% hydrated SiO 2,40% ~ 85% wetting agent, 0.8% ~ 2% thickening agent, 1% ~ 3% surfactant, 0.01 ~ 1% antiseptic, 0.3% ~ 3% essence, deionized water are added into 100%.
Described nutrient substance is vitamin C and Margarita hydrolyzed solution compositions, or one or both the mixture in vitamin C and Margarita hydrolyzed solution compositions and xylitol, Vitamin E acetate.
The preparation method of described vitamin C and Margarita hydrolyzed solution compositions comprises the following steps: (a) in Margarita, add and the citric acid of Margarita identical weight part and the water of twice Margarita weight portion, make it act at normal temperatures 1-2 hour; (b) be incorporated as the carase of Margarita weight 0.01%, at 60-70 ℃ of effect 4-6 hour; (c) supernatant of getting mixture obtains required Margarita hydrolyzed solution; (d) take vitamin C and join under stirring condition in the Margarita hydrolyzed solution of corresponding weight ratio; (e) mixture in step (d) is uniformly mixed, can obtains described oral care composition.Wherein the weight ratio of vitamin C and Margarita hydrolyzed solution is 0.001 ~ 1:1.
Described wetting agent is a kind of or its mixture in glycerol, sorbitol, the molecular weight Polyethylene Glycol between 200-1500.
Described thickening agent is a kind of or its mixture in carrageenan, hydroxyethyl-cellulose, carboxymethyl cellulose, HANSHENGJIAO, guar gum, carbomer.
Described surfactant is a kind of or its mixture in sodium lauryl sulphate, cocoyl sodium isethionate, lauroyl propylhomoserin sodium.
Described antiseptic is a kind of in sodium benzoate, methyl hydroxybenzoate, ethyl hydroxybenzoate, potassium sorbate, butyl hydroxybenzoate and methyl hydroxybenzoate sodium.
A kind of oral cavity caring toothpaste composition for children, described compositions is comprised of following raw materials by weight: 40% ~ 73% sorbitol, 2% ~ 7% PEG-4000,2% glycerol, 0.2% ~ 0.5% sodium benzoate, 5% ~ 15% nutrient substance, 8% ~ 24% hydrated SiO 2,0.8% ~ 0.2% carboxyl methyl cellulose-IH9,1% ~ 3% sodium lauryl sulphate, 0.3% ~ 3% essence, deionized water is added into 100%.
A kind of oral cavity caring toothpaste composition for children, described compositions is comprised of following raw materials by weight: 40% ~ 73% sorbitol, 2% ~ 7% PEG-4000,2% glycerol, 0.2% ~ 0.5% sodium benzoate, 5% ~ 15% vitamin C and Margarita hydrolyzed solution compositions, 8% ~ 24% hydrated SiO 2,0.8% ~ 2% carboxyl methyl cellulose-IH9,1% ~ 3% sodium lauryl sulphate, 0.3% ~ 3% essence, deionized water is added into 100%.
Described vitamin C and Margarita hydrolyzed solution compositions have the following advantages: a certain amount of calcium ion and micromolecule polypeptide are arranged in Margarita hydrolyzed solution, thereby guarantee ascorbic stability; Vitamin C and Margarita hydrolyzed solution have appropriate blend proportion, guarantee that ascorbic amount is less than the amount of Margarita hydrolyzed solution; Vitamin C and Margarita hydrolyzed solution combined effect, can remove free radical common in oral cavity, and the kind of removing free radical is better than single active component or other antioxidant.
Beneficial effect of the present invention: added vitamin C and Margarita hydrolyzed solution compositions, can help to supplement the tooth required nutrition of growing up, for the oral problem origin, given the nutrition of gingiva abundance, healthy mouth, strong gingiva, firm tooth.
The specific embodiment
Embodiment mono-
Sorbitol 70%
PEG-4000 7%
Glycerol 2%
Sodium benzoate 0.2%
Vitamin C and Margarita hydrolyzed solution compositions 5%
Xylitol 5%
Hydrated SiO 2 8%
Carboxyl methyl cellulose-IH9 0.8%
Sodium lauryl sulphate 1%
Essence 0.3%
Deionized water is added into 100%
Embodiment bis-
Sorbitol 40%
PEG-4000 2%
Glycerol 2%
Sodium benzoate 0.5%
Vitamin C and Margarita hydrolyzed solution compositions 15%
Hydrated SiO 2 24%
Carboxyl methyl cellulose-IH9 0.8%
Sodium lauryl sulphate 3%
Essence is appropriate
Deionized water is added into 100%
The production of dentifrice composition of the present invention can adopt the method for any routine.Vitamin C and Margarita hydrolyzed solution compositions, xylitol, Vitamin E acetate can directly be used water dissolution, also can simply be blended in and add in toothpaste matrix.
Protect gum clinical trial checking:
One. preparation of samples
The sample that sample A is embodiment mono-
Sample B is the general children's toothpaste that uses
Two. test method:
EXPERIMENTAL DESIGN: adopt double blinding, Method of Random Test
Test index: gingival index (GI), sulcular bleeding index (SBI)
Three. experiment process:
The study subject oral cavity is divided into 6 districts, take respectively 16(17), 11(21), 26(27), 36(37), 31(41), 46(47) be the index tooth, record baseline gingival index (GI) and the sulcular bleeding index (SBI) of each tooth.
Study subject is used separately and is provided to toothpaste and toothbrush, check These parameters after brushing teeth on request 4 weeks, Evaluated effect.
Four. the test grouping:
Screening meets inclusive criteria and exclusion standard person, by random table, is divided into two groups of A, B, and two groups basic identical on health, the gingivitis order of severity, age (2-6 year), sex ratio.
Five. result of the test:
Two groups of clinical testing data contrasts
Annotate: n is expressed as the number taken one's test
Result of the test: after using sample A surrounding, experimenter's gingivitis situation: bleeding is examined in red and swollen, hemorrhage gingivitis, periodontitis outward appearance and spy all obvious improvement.
The present invention relates to a kind of oral cavity caring toothpaste composition for children, energy is the nutrition gingiva effectively, and the prophylaxis of teeth disease produces.Contain multiple nutritional components in dentifrice composition: comprise vitamin C and Margarita hydrolyzed solution compositions, or one or both the mixture in vitamin C and Margarita hydrolyzed solution compositions and xylitol, Vitamin E acetate, nutrition tooth, gingiva are provided, healthy mouth, strong gingiva, the effect of firm tooth.And adopt soft abrasive silica, take care of one's teeth.
The announcement of book and instruction according to the above description, those skilled in the art in the invention can also be changed and be revised above-mentioned embodiment.Therefore, the present invention is not limited to the specific embodiment disclosed and described above, to modifications and changes more of the present invention, also should fall in the protection domain of claim of the present invention.In addition, although used some specific terms in this description, these terms just for convenience of description, do not form any restriction to the present invention.
Claims (7)
1. an oral cavity caring toothpaste composition for children, it is characterized in that: described compositions is comprised of following raw materials by weight:
Described nutrient substance is vitamin C and Margarita hydrolyzed solution compositions, or one or both the mixture in vitamin C and Margarita hydrolyzed solution compositions and xylitol, Vitamin E acetate;
The preparation method of described Margarita hydrolyzed solution comprises the following steps: (a) in Margarita, add and the citric acid of Margarita identical weight part and the water of twice Margarita weight portion, make it act at normal temperatures 1-2 hour; (b) be incorporated as the carase of Margarita weight 0.01%, at 60-70 ℃ of effect 4-6 hour; (c) supernatant of getting mixture obtains required Margarita hydrolyzed solution.
2. dentifrice composition according to claim 1, it is characterized in that: described wetting agent is a kind of or its mixture in glycerol, sorbitol, the molecular weight Polyethylene Glycol between 200-1500.
3. dentifrice composition according to claim 1, it is characterized in that: described thickening agent is a kind of or its mixture in carrageenan, hydroxyethyl-cellulose, carboxymethyl cellulose, HANSHENGJIAO, guar gum, carbomer.
4. dentifrice composition according to claim 1, it is characterized in that: described surfactant is a kind of or its mixture in sodium lauryl sulphate, cocoyl sodium isethionate, lauroyl propylhomoserin sodium.
5. dentifrice composition according to claim 1 is characterized in that: described antiseptic is a kind of in sodium benzoate, methyl hydroxybenzoate, ethyl hydroxybenzoate, potassium sorbate, butyl hydroxybenzoate and methyl hydroxybenzoate sodium.
6. dentifrice composition according to claim 1, it is characterized in that: described compositions is formulated by following raw materials by weight:
Described nutrient substance is vitamin C and Margarita hydrolyzed solution compositions, or one or both the mixture in vitamin C and Margarita hydrolyzed solution compositions and xylitol, Vitamin E acetate.
7. dentifrice composition according to claim 6, it is characterized in that: described compositions is formulated by following raw materials by weight:
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2012100029890A CN102499903B (en) | 2012-01-06 | 2012-01-06 | Oral cavity caring toothpaste composition for children |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2012100029890A CN102499903B (en) | 2012-01-06 | 2012-01-06 | Oral cavity caring toothpaste composition for children |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN102499903A CN102499903A (en) | 2012-06-20 |
| CN102499903B true CN102499903B (en) | 2013-12-11 |
Family
ID=46212081
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN2012100029890A Active CN102499903B (en) | 2012-01-06 | 2012-01-06 | Oral cavity caring toothpaste composition for children |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN102499903B (en) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105125417A (en) * | 2015-08-18 | 2015-12-09 | 纳诺神蜂（福建）个人护理用品有限公司 | Fluoride-free, non-pigment and saccharin-sodium-free micro-foam type edible children toothpaste and preparation method thereof |
| CN105147583B (en) * | 2015-09-30 | 2018-01-02 | 福建春辉生物工程有限公司 | A kind of children special-purpose toothpaste containing Sasanguasaponin and preparation method thereof |
| CN106606455A (en) * | 2017-01-22 | 2017-05-03 | 福建农林大学 | Konjac glucomannan child toothpaste and preparation method thereof |
| CN107998010A (en) * | 2017-11-14 | 2018-05-08 | 名臣健康用品股份有限公司 | A kind of virgin growth toothpaste of benefit |
| CN107982073A (en) * | 2017-12-24 | 2018-05-04 | 洛阳名力科技开发有限公司 | Children special-purpose toothpaste |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101889970B (en) * | 2009-05-20 | 2012-06-06 | 广州薇美姿个人护理用品有限公司 | Natural floride-free edible transparent health-care toothpaste for children |
| CN101889969B (en) * | 2009-05-20 | 2012-09-12 | 广州薇美姿个人护理用品有限公司 | Natural fluorine-free edible transparent child nutrition toothpaste |
-
2012
- 2012-01-06 CN CN2012100029890A patent/CN102499903B/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| CN102499903A (en) | 2012-06-20 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN103385805B (en) | A kind of benefit is benefit combination children's toothpaste in evening and one benefit children's toothpaste in evening early | |
| CN104666185B (en) | A kind of liquid tooth paste and preparation method thereof | |
| JP7209425B2 (en) | Toothpaste to deliver allergens to the oral mucosa | |
| CN102499903B (en) | Oral cavity caring toothpaste composition for children | |
| CN103830145B (en) | A kind of toothpaste containing biological peptide and Chinese medicine | |
| CN106963662B (en) | Color-changing toothpaste for children and preparation method and application thereof | |
| CN101010091A (en) | Oral care composition comprising essential oils | |
| CN105476947A (en) | Toothpaste containing periplaneta Americana and preparation method thereof | |
| CN101889970A (en) | Natural floride-free edible transparent health-care toothpaste for children | |
| CN105193638A (en) | Application of astaxanthin in toothpaste | |
| US9554986B2 (en) | Oral care composition | |
| CN102743323B (en) | Chewing tablet | |
| RU2457829C2 (en) | Mineral and vitamin complex for strengthening tooth enamel, composition for oral cavity hygiene and toothpaste | |
| Sarkar et al. | Overview of the skeleton significance of toothpaste formulation, evaluation and historical perspectives: Insights from Bangladesh’s toothpaste industry | |
| CN106581159A (en) | Children oral care composition and combination children toothpaste suitable for use in the morning and in the evening | |
| CN107007538B (en) | Oral care composition containing marine elements, application of oral care composition and toothpaste containing marine elements | |
| Vertuan et al. | The in vitro effect of dentifrices with activated charcoal on eroded teeth | |
| US9554974B2 (en) | Oral dentrifice power and method | |
| CN106420497A (en) | Fibroin mouth wash and preparation method thereof | |
| CN102499902B (en) | Oral cavity care composition | |
| CN110801417A (en) | Toothpaste for children | |
| CN104983610B (en) | A kind of product formula for anti-caries removing abnormal flavor in oral cavity | |
| CN107184530A (en) | A kind of mouthwash and preparation method thereof | |
| US10143633B2 (en) | Treating cariogenic diseased oral biofilm with elevated pH | |
| US20180344594A1 (en) | Oral Care Products and Methods |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| C41 | Transfer of patent application or patent right or utility model | ||
| TR01 | Transfer of patent right |
Effective date of registration: 20151216 Address after: 510665 Guangzhou City, Tianhe District Province Road, building No. 64, No. 66 West, room 704, 705 Patentee after: Guangzhou Weimeizi Industrial Co., Ltd. Address before: 510665 Guangdong city of Guangzhou province Tianhe District Road 51 new science and Technology Building 1 building 402 room Patentee before: Guangzhou Weimeizi Personal Care Supplies Co., Ltd. |
|
| TR01 | Transfer of patent right | ||
| TR01 | Transfer of patent right |
Effective date of registration: 20210428 Address after: 510555 room 922, No.2, Tengfei 1st Street, Zhongxin Guangzhou Knowledge City, Huangpu District, Guangzhou City, Guangdong Province (office only) Patentee after: Guangzhou Shuke Industrial Co.,Ltd. Address before: 510665, 64, 66, West 704 and 705, Jianzhong Road, Guangzhou, Guangdong, Tianhe District Patentee before: GUANGZHOU WEIMEIZI INDUSTRIAL Co.,Ltd. |