CN106606455A - Konjac glucomannan child toothpaste and preparation method thereof - Google Patents
Konjac glucomannan child toothpaste and preparation method thereof Download PDFInfo
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/98—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution of animal origin
- A61K8/987—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution of animal origin of species other than mammals or birds
- A61K8/988—Honey; Royal jelly, Propolis
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/19—Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61K8/00—Cosmetics or similar toiletry preparations
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- A61K8/19—Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
- A61K8/25—Silicon; Compounds thereof
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- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/34—Alcohols
- A61K8/345—Alcohols containing more than one hydroxy group
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
- A61K8/44—Aminocarboxylic acids or derivatives thereof, e.g. aminocarboxylic acids containing sulfur; Salts; Esters or N-acylated derivatives thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/60—Sugars; Derivatives thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/67—Vitamins
- A61K8/676—Ascorbic acid, i.e. vitamin C
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
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- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/67—Vitamins
- A61K8/678—Tocopherol, i.e. vitamin E
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/73—Polysaccharides
- A61K8/731—Cellulose; Quaternized cellulose derivatives
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/73—Polysaccharides
- A61K8/737—Galactomannans, e.g. guar; Derivatives thereof
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
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- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/98—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution of animal origin
- A61K8/987—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution of animal origin of species other than mammals or birds
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q11/00—Preparations for care of the teeth, of the oral cavity or of dentures; Dentifrices, e.g. toothpastes; Mouth rinses
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q17/00—Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
- A61Q17/005—Antimicrobial preparations
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/20—Chemical, physico-chemical or functional or structural properties of the composition as a whole
- A61K2800/28—Rubbing or scrubbing compositions; Peeling or abrasive compositions; Containing exfoliants
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
- A61K2800/48—Thickener, Thickening system
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Abstract
The invention relates to konjac glucomannan child toothpaste and a preparation method thereof. The preparation method of the konjac glucomannan child toothpaste comprises preparation of a friction agent, preparation of a thickener, preparation of a sweetening agent, preparation of a nutrient aid, preparation of a foaming agent/mild surfactant complex, preparation of materials, preparation of liquid and preparation of the toothpaste. In the konjac glucomannan child toothpaste, pearl powder, food grade silicon dioxide, activated carbon, konjac glucomannan, propolis, xylitol, fructo-oligosaccharide and maltooligosaccharide are taken as major materials. The prepared konjac glucomannan child toothpaste is bright and fine in appearance, is prepared from natural raw materials, is mild and free from irritation, has the multiple effects of nutrition and health care through reasonable blending of the raw materials besides the function of effectively removing teeth stains, is suitable for children, is simple in process and convenient to operate, and can be industrially produced continuously.
Description
Technical field
The present invention relates to a kind of article of everyday use and preparation method thereof, and in particular to a kind of Rhizoma amorphophalli glucomannan children's toothpaste and its
Preparation method, belongs to oral care product technical field.
Background technology
With the improvement and the enhancing of health consciousness of people's living standard, oral hygiene more becomes popular daily concern
One of focus, toothpaste have then become requisite oral cavity cleaning hygienic article in people's daily life.For preschooler
Tooth and the physiological characteristicies in oral cavity, which is excessively taken in snacks, sweets etc. and is unfavorable for the self-cleaning food of tooth often because of improper diet,
And cause the oral diseases such as dental caries, gingivitiss；Meanwhile, the length of one's sleep of child is longer, and this stage oral cavity remains static, saliva
Liquid secretion is few, and self-cleaning action is poor, is more beneficial for bacterial reproduction, and dental caries probability is suffered from increase, and then directly affects the daily life of child
With it is healthy.For this purpose, the oral problem of child once becomes the significant problem of puzzlement child and the head of a family.
As dentifrice abrasives hardness of being grown up is high, frictional force is big, formula components are complicated and zest is strong, if being used for child Ze Yi
Permanent teeth is damaged, its oral environment is destroyed.Therefore, child brushes teeth and should use children special-purpose toothpaste.Make a general survey of existing on the market at present
Children's toothpaste, suffers from the drawback that more：First, to pursue effect, children's toothpaste often adds the chemical compositions such as fluoride, but due to
It is incomplete that child swallows physiogeny, and excess intake fluorine easily causes calcium loss and forms dental fluorosis, so as to affect preschool youngster
Virgin body development, causes tooth to become fragile；Second, to pursue safety, so the formula components of children's toothpaste are reduced, using day
So edibility material, causes product efficacy ensure, for the oral problem of child, does not reach effectively particular for dental caries
Prevention effect.
A kind of patent of invention " manufacture method of children's toothpaste " of Application No. 201410459260.5（The applying date：2014-
09-11）, describe a kind of children's toothpaste being made by compositions such as orange peel, Nodus Nelumbinis Rhizomatis, Mel, Oleum menthae, Oleum Cocois.Produce
Product feature is the chemical composition that made toothpaste is not used synthetic, in good taste, edible.But which is not directed to youngster
The oral disease that Tong Yi occurs carries out process improving, in terms of effect of toothpaste has limitation.
A kind of patent of invention " children's toothpaste " of Application No. 201610535324.4（The applying date：2016-07-08）, it is situated between
Continued a kind of child's tooth being made by compositions such as Oleum Caryophylli, Oleum menthae, calcium hydrogen phosphate, oleum Citri sinensis, Sucus Luffae, Margarita powder
Cream.Products characteristics are that made toothpaste is not fluorine-containing, and content of chemical substances is few, safe and reliable, whitening antibacterial.But which is in product
Also there is limitation in effect, lack health-care effect, still need to be improved in product formula.
The content of the invention
It is an object of the invention to provide a kind of Rhizoma amorphophalli glucomannan children's toothpaste and preparation method thereof.
A kind of preparation method of Rhizoma amorphophalli glucomannan children's toothpaste of the present invention, it is characterised in that preparation process is as follows：
（1）Prepare abrasivuss：In terms of mass parts, 5 ~ 10 parts of Margarita powder is taken, 7 ~ 13 parts of food grade silicon dioxide, 2 ~ 6 parts of activated carbon,
Mix, the abrasivuss particle diameter is 40 ~ 50 μm；
（2）Prepare thickening agent：Take 0.03 ~ 0.05 part of Rhizoma amorphophalli glucomannan, 0.5 ~ 0.7 part of propolis, sodium carboxymethyl cellulose 0.3 ~
0.6 part, mix；
（3）Prepare sweeting agent：1 ~ 3 part of xylitol is taken, 1 ~ 2 part of oligofructose, 0.5 ~ 1.5 part of Oligomeric maltose are mixed；
（4）Prepare nutritional auxiliary：1 ~ 2.5 part of green tea powder is taken, 0.1 ~ 0.5 part of vitamin C, 0.1 ~ 0.3 part of Vitamin E are mixed；
（5）Prepare foaming agent/gentle surfactant blend：Foaming agent and gentle surfactant are taken, is 1 in mass ratio:
0.5 ~ 2.5 ratio is mixed, standby；
（6）Dispensing：Take 15 ~ 25 parts of abrasivuss, 0.5 ~ 1.2 part of thickening agent, foaming agent/gentle surfactant blend 3 ~ 3.75
Part, 0.3 ~ 0.7 part of natural edible essence is injected after mixing in powder material tank, standby；
（7）Prepare liquid material：15 ~ 35 parts of ionized water is removed in liquid tank, 1 ~ 5 part of sweeting agent, 0.9 ~ 3 part of nutritional auxiliary is added,
30 ~ 60 parts of wetting agent, stirring and dissolving is standby；
（8）Prepare toothpaste：Take step（6）、（7）Material on Manufacturing medicine extract machine, routinely paste manufacture process, makes Rhizoma amorphophalli glucomannan
Children's toothpaste.
The wetting agent is glycerol；Foaming agent is sodium lauroyl sarcosine.
Advantages of the present invention and beneficial effect：Rhizoma amorphophalli glucomannan children's toothpaste of the present invention, with Margarita powder, food stage dioxy
SiClx, activated carbon, Rhizoma amorphophalli glucomannan, propolis, xylitol, oligofructose, Oligomeric maltose etc. are main material.Using Rhizoma amorphophalli
The distinctive thickening properties of glucomannoglycan, give children's toothpaste with sparkling and crystal-clear fine and smooth outward appearance；Meanwhile, Rhizoma amorphophalli glucomannan is used as natural
Water soluble dietary fiber, with splendid health-care effect, into after child's digestive system, can help improve the intestinal of child
Group, promotes gastrointestinal peristalsiss, so as to improve abilities of digestive and absorption of the child to nutrient substance, and can also play enhancing immunization programs for children
Effect；By the use of xylitol, oligofructose, Oligomeric maltose compounding use as sweeting agent, oral cavity acid-base balance can be maintained,
Suppress pernicious bacteria to remain breeding in the oral cavity, reduce the formation of bacterial plaque, reach the effect of preventing decayed tooth；Using sodium lauroyl sarcosine
Used as foaming agent, which does not gently stimulate, and can produce the foam of exquisiteness, so that effectively removing the oil of oral cavity and dental surface attachment
Stain, spot, antibiotic and sterilizing, and easy-to-use clear water rinse are clean, noresidue.
To sum up, Rhizoma amorphophalli glucomannan children's toothpaste of the invention, the sparkling and crystal-clear exquisiteness of outward appearance, raw material is natural, gently do not stimulate,
While effectively removing tooth stain, can pass through the reasonable compounding of raw material, interaction, reach integrate nutrition, health care it is multiple
Effect, be adapted to child use, and process is simple, be easy to operation, industrialization can be carried out and continuously produced.The Amorphophallus rivieri glucomannan of the present invention
Comparison of the polysaccharide children's toothpaste with commercial like product in terms of nutritional health function, cleaning capacity and protection effect, as a result such as
Shown in table 1.
Table 1, Rhizoma amorphophalli glucomannan children's toothpaste are compared with commercial like product
Comparative result shows that the Rhizoma amorphophalli glucomannan children's toothpaste of the present invention is in nutritional health function, cleaning capacity and protection work(
The properties such as effect are excellent compared with commercial like product.
Specific embodiment
For fully open Rhizoma amorphophalli glucomannan children's toothpaste of the present invention and preparation method thereof, with reference to embodiment to the present invention
It is described in further detail.
Embodiment 1, a kind of preparation method of Rhizoma amorphophalli glucomannan children's toothpaste, comprise the following steps：
（1）Prepare abrasivuss：In terms of mass parts, 5 parts of Margarita powder is taken, 8 parts of food grade silicon dioxide, 3 parts of activated carbon are mixed, institute
State abrasivuss particle diameter and be 45 μm；
（2）Prepare thickening agent：0.03 part of Rhizoma amorphophalli glucomannan is taken, 0.6 part of propolis, 0.5 part of sodium carboxymethyl cellulose are mixed；
（3）Prepare sweeting agent：3 parts of xylitol is taken, 1 part of oligofructose, 0.5 part of Oligomeric maltose are mixed；
（4）Prepare nutritional auxiliary：2 parts of green tea powder is taken, 0.4 part of vitamin C, 0.1 part of Vitamin E are mixed；
（5）Prepare foaming agent/gentle surfactant blend：Foaming agent and gentle surfactant are taken, is 1 in mass ratio:2
Ratio mix, it is standby；
（6）Dispensing：Take 16 parts of abrasivuss, 1.13 parts of thickening agent, foaming agent/gentle 3 parts of surfactant blend, natural edible
0.4 part of essence, injects after mixing in powder material tank, standby；
（7）Prepare liquid material：32.47 parts of ionized water is removed in liquid tank, 4.5 parts of sweeting agent, 2.5 parts of nutritional auxiliary is added, is protected
40 parts of humectant, stirring and dissolving is standby；
（8）Prepare toothpaste：Take step（6）、（7）Material on Manufacturing medicine extract machine, routinely paste manufacture process, makes Rhizoma amorphophalli glucomannan
Children's toothpaste.
Embodiment 2, a kind of preparation method of Rhizoma amorphophalli glucomannan children's toothpaste, comprise the following steps：
（1）Prepare abrasivuss：In terms of mass parts, 9 parts of Margarita powder is taken, 7 parts of food grade silicon dioxide, 5 parts of activated carbon are mixed, institute
State abrasivuss particle diameter and be 50 μm；
（2）Prepare thickening agent：0.05 part of Rhizoma amorphophalli glucomannan is taken, 0.5 part of propolis, 0.4 part of sodium carboxymethyl cellulose are mixed；
（3）Prepare sweeting agent：2 parts of xylitol is taken, 2 parts of oligofructose, 1 part of Oligomeric maltose are mixed；
（4）Prepare nutritional auxiliary：2.5 parts of green tea powder is taken, 0.3 part of vitamin C, 0.2 part of Vitamin E are mixed；
（5）Prepare foaming agent/gentle surfactant blend：Foaming agent and gentle surfactant are taken, is 1 in mass ratio:
1.5 ratio is mixed, standby；
（6）Dispensing：21 parts of abrasivuss, 0.95 part of thickening agent, foaming agent/gentle 3.75 parts of surfactant blend is taken, it is natural
0.6 part of edible essence, injects after mixing in powder material tank, standby；
（7）Prepare liquid material：15.7 parts of ionized water is removed in liquid tank, 5 parts of sweeting agent, 3 parts of nutritional auxiliary, wetting agent 50 is added
Part, stirring and dissolving is standby；
（8）Prepare toothpaste：Take step（6）、（7）Material on Manufacturing medicine extract machine, routinely paste manufacture process, makes Rhizoma amorphophalli glucomannan
Children's toothpaste.
The foregoing is only presently preferred embodiments of the present invention, all impartial changes done according to scope of the present invention patent with
Modification, should all belong to the covering scope of the present invention.
Claims (9)
1. a kind of preparation method of Rhizoma amorphophalli glucomannan children's toothpaste, it is characterised in that preparation process is as follows：
（1）Prepare abrasivuss：In terms of mass parts, 5 ~ 10 parts of Margarita powder is taken, 7 ~ 13 parts of food grade silicon dioxide, 2 ~ 6 parts of activated carbon,
Mix, the abrasivuss particle diameter is 40 ~ 50 μm；
（2）Prepare thickening agent：Take 0.03 ~ 0.05 part of Rhizoma amorphophalli glucomannan, 0.5 ~ 0.7 part of propolis, sodium carboxymethyl cellulose 0.3 ~
0.6 part, mix；
（3）Prepare sweeting agent：1 ~ 3 part of xylitol is taken, 1 ~ 2 part of oligofructose, 0.5 ~ 1.5 part of Oligomeric maltose are mixed；
（4）Prepare nutritional auxiliary：1 ~ 2.5 part of green tea powder is taken, 0.1 ~ 0.5 part of vitamin C, 0.1 ~ 0.3 part of Vitamin E are mixed；
（5）Prepare foaming agent/gentle surfactant blend：Foaming agent and gentle surfactant are taken, is 1 in mass ratio:
0.5 ~ 2.5 ratio is mixed, standby；
（6）Dispensing：Take 15 ~ 25 parts of abrasivuss, 0.5 ~ 1.2 part of thickening agent, foaming agent/gentle surfactant blend 3 ~ 3.75
Part, 0.3 ~ 0.7 part of natural edible essence is injected after mixing in powder material tank, standby；
（7）Prepare liquid material：15 ~ 35 parts of ionized water is removed in liquid tank, 1 ~ 5 part of sweeting agent, 0.9 ~ 3 part of nutritional auxiliary is added,
30 ~ 60 parts of wetting agent, stirring and dissolving is standby；
（8）Prepare toothpaste：Take step（6）、（7）Material on Manufacturing medicine extract machine, routinely toothpaste technique processed, makes konjak portuguese gansu polyose
Sugared children's toothpaste.
2. a kind of preparation method of Rhizoma amorphophalli glucomannan children's toothpaste according to claim 1, it is characterised in that the system
Standby abrasivuss：5 parts of Margarita powder is taken, 8 parts of food grade silicon dioxide, 3 parts of activated carbon are mixed, and the abrasivuss particle diameter is 45 μm.
3. a kind of preparation method of Rhizoma amorphophalli glucomannan children's toothpaste according to claim 1, it is characterised in that the system
Standby thickening agent：0.03 part of Rhizoma amorphophalli glucomannan is taken, 0.6 part of propolis, 0.5 part of sodium carboxymethyl cellulose are mixed.
4. a kind of preparation method of Rhizoma amorphophalli glucomannan children's toothpaste according to claim 1, it is characterised in that the system
Standby sweeting agent：3 parts of xylitol is taken, 1 part of oligofructose, 0.5 part of Oligomeric maltose are mixed.
5. a kind of preparation method of Rhizoma amorphophalli glucomannan children's toothpaste according to claim 1, it is characterised in that the system
Standby nutritional auxiliary：2 parts of green tea powder is taken, 0.4 part of vitamin C, 0.1 part of Vitamin E are mixed.
6. a kind of preparation method of Rhizoma amorphophalli glucomannan children's toothpaste according to claim 1, it is characterised in that the system
Preparation infusion/gentle surfactant blend：Foaming agent and gentle surfactant are taken, is 1 in mass ratio:2 ratio is mixed
It is even.
7. the preparation method of a kind of Rhizoma amorphophalli glucomannan children's toothpaste according to claim 1, it is characterised in that described to match somebody with somebody
Material：Take 16 parts of abrasivuss, 1.13 parts of thickening agent, foaming agent/gentle 3 parts of surfactant blend, natural edible essence 0.4
Part, inject in powder material tank after mixing.
8. a kind of preparation method of Rhizoma amorphophalli glucomannan children's toothpaste according to claim 1, it is characterised in that the system
Standby liquid material：32.47 parts of ionized water is removed in liquid tank, add 4.5 parts of sweeting agent, 2.5 parts of nutritional auxiliary, 40 parts of wetting agent,
Stirring and dissolving.
9. the Rhizoma amorphophalli glucomannan children's toothpaste that prepared by the either method by described in claim 1-8.
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109645125A (en) * | 2018-12-26 | 2019-04-19 | 福建农林大学 | Brown rice cow's milk nutrition space food and preparation method thereof |
| CN110897992A (en) * | 2020-01-02 | 2020-03-24 | 广东立爽生物科技有限公司 | Halitosis removing toothpaste and preparation method thereof |
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| US20030152524A1 (en) * | 2001-12-04 | 2003-08-14 | Kao Corporation | Oral composition |
| CN102499903A (en) * | 2012-01-06 | 2012-06-20 | 广州薇美姿个人护理用品有限公司 | Oral cavity caring toothpaste composition for children |
| CN103385805A (en) * | 2013-07-18 | 2013-11-13 | 广州薇美姿个人护理用品有限公司 | Composite children toothpaste suitable for use in the morning and in the evening and children toothpaste suitable for use in the evening |
| CN104905987A (en) * | 2015-05-29 | 2015-09-16 | 广州立白企业集团有限公司 | Child toothpaste composition |
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2017
- 2017-01-22 CN CN201710045944.4A patent/CN106606455A/en active Pending
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20030152524A1 (en) * | 2001-12-04 | 2003-08-14 | Kao Corporation | Oral composition |
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