CN102423480B - Trifoliate orange/rhizoma atractylodis macrocephalae/rhizoma polygonati/rhizoma cyperi/shelled cedar seed soup for gastroptosis - Google Patents
Trifoliate orange/rhizoma atractylodis macrocephalae/rhizoma polygonati/rhizoma cyperi/shelled cedar seed soup for gastroptosis Download PDFInfo
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- CN102423480B CN102423480B CN201110433963.7A CN201110433963A CN102423480B CN 102423480 B CN102423480 B CN 102423480B CN 201110433963 A CN201110433963 A CN 201110433963A CN 102423480 B CN102423480 B CN 102423480B
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Abstract
The invention relates to the field of traditional Chinese medicine formulae, particularly a trifoliate orange/rhizoma atractylodis macrocephalae/rhizoma polygonati/rhizoma cyperi/shelled cedar seed soup for gastroptosis. The soup is prepared from the following active pharmaceutical ingredients in percentage by weight: 5-8% of fructus aurantii, 5-8% of immature bitter orange, 7-10% of semen dolichoris album, 4-6% of rhizoma atractylodis macrocephalae, 12-16% of roasted radix astragali, 4-6% of rhizoma polygonati, 6-9% of dalbergia wood, 2-5% of rhizoma cyperi, 2-4% of elecampane, 1-3% of clove, 2-5% of shelled cedar seed, 4-7% of picrorhiza rhizome, 4-6% of skunk bugbane, 4-6% of ginger, 5-8% of rhizoma corydalis, 1-3% of Evodia rutaecarpa, 4-7% of roasted licorice root and 5-8% of Arillus Longan. The soup is prepared by the following steps: soaking the active pharmaceutical ingredients in water, decocting, and removing dregs to obtain a filtrate. The soup for treating gastroptosis has the advantages of high curative effect and no toxic or side effect, can be easily accepted by patients, has the effects of strengthening the middle-jiao, invigorating qi, consolidating qi, soothing the liver, promoting the circulation of qi, soothing the stomach, resolving phlegm, relieving the depressed liver, promoting digestion and the like, and is applicable to early, medium and late gastroptosis.
Description
Technical field
The present invention relates to a kind of Chinese patent medicine preparation, specifically the white Colophonium core of a kind of trifoliate orange for gastroptosis soup.
Background technology
As everyone knows, gastroptosis refers to that with lesser gastric curvature angular incisure, lower than below ilium ridge on line, pyloric cap is offset a kind of disease into main physical signs left.With 30～50 years old common, women is more than male, have clinically a series of symptoms of digestive tract as abdominal distention, Upper abdominal pain, inappetence, dyspepsia, constipation, nausea and vomiting, the underwater sound etc. shakes.Due to gastroptosis series of symptoms, siege patient, makes its mental burden overweight, easily produces the mental symptoms such as insomnia, headache, is seriously tormenting patient physically and mentally healthy, is common clinical.Adopt of doctor trained in Western medicine suited the medicine to the illness and in good time operation method more, and not only effect is not good enough and patient is difficult to accept.
Summary of the invention
Object of the present invention is exactly in order to overcome above-mentioned existing technical deficiency, provides a kind of cost low, and treatment gastroptosis curative effect is high, have no side effect, patient is acceptant, has invigorating the spleen and replenishing QI astringency inducing, soothing the liver relieving QI stagnancy in the stomach, the eliminating phlegm and relaxing heart effect such as help digestion, is applicable to early, middle and late each phase gastroptosis.
The technical scheme that the present invention solves the problems of the technologies described above employing is: the white Colophonium core of a kind of trifoliate orange for gastroptosis soup, adopt Fructus Aurantii, Fructus Aurantii Immaturus, Semen Lablab Album, the Rhizoma Atractylodis Macrocephalae, Radix Astragali Mongolici (processed), Rhizoma Polygonati, Lignum Dalbergiae Odoriferae, Rhizoma Cyperi, Radix Inulae, Flos Caryophylli, Semen Platycladi, Rhizoma Picrorhizae, Rhizoma Cimicifugae, Rhizoma Zingiberis Recens, Rhizoma Corydalis comet, Fructus Evodiae, Radix Glycyrrhizae Preparata, Arillus Longan is crude drug, be soaked in water, the filtrate of removing slag after decocting to obtain, its technical characterictic is, the percentage by weight that crude drug forms is counted, Fructus Aurantii 5～8%, Fructus Aurantii Immaturus 5～8%, Semen Lablab Album 7～10%, the Rhizoma Atractylodis Macrocephalae 4～6%, Radix Astragali Mongolici (processed) 12～16%, Rhizoma Polygonati 4～6%, Lignum Dalbergiae Odoriferae 6～9%, Rhizoma Cyperi 2～5%, Radix Inulae 2～4%, Flos Caryophylli 1～3%, Semen Platycladi 2～5%, Rhizoma Picrorhizae 4～7%, Rhizoma Cimicifugae 4～6%, Rhizoma Zingiberis Recens 4～6%, Rhizoma Corydalis comet 5～8%, Fructus Evodiae 1～3%, Radix Glycyrrhizae Preparata 4～7%, Arillus Longan 5～8%.
Effect of the present invention is, treatment gastroptosis curative effect is high, has no side effect, and patient is easy to accept, and has invigorating the spleen and replenishing QI astringency inducing, soothing the liver relieving QI stagnancy in the stomach, and the eliminating phlegm and relaxing heart effect such as help digestion, is applicable to early, middle and late each phase gastroptosis.
The specific embodiment
Below in conjunction with embodiment, the invention will be further described:
Embodiment 1: adopting Fructus Aurantii, Fructus Aurantii Immaturus, Semen Lablab Album, the Rhizoma Atractylodis Macrocephalae, Radix Astragali Mongolici (processed), Rhizoma Polygonati, Lignum Dalbergiae Odoriferae, Rhizoma Cyperi, Radix Inulae, Flos Caryophylli, Semen Platycladi, Rhizoma Picrorhizae, Rhizoma Cimicifugae, Rhizoma Zingiberis Recens, Rhizoma Corydalis comet, Fructus Evodiae, Radix Glycyrrhizae Preparata, Arillus Longan is that crude drug is prepared from.Every pair of its component (% by weight) is Fructus Aurantii 6, Fructus Aurantii Immaturus 6, Semen Lablab Album 9, the Rhizoma Atractylodis Macrocephalae 6, Radix Astragali Mongolici (processed) 14, Rhizoma Polygonati 5, Lignum Dalbergiae Odoriferae 8, Rhizoma Cyperi 3, Radix Inulae 3, Flos Caryophylli 2, Semen Platycladi 3, Rhizoma Picrorhizae 5, Rhizoma Cimicifugae 6, Rhizoma Zingiberis Recens 5, Rhizoma Corydalis comet 6, Fructus Evodiae 2, Radix Glycyrrhizae Preparata 5, Arillus Longan 6.Getting above-mentioned 18 taste crude drug gross weights is 173 grams, first Flos Caryophylli is smashed to pieces, at room temperature 18 taste Chinese herbal medicine is added water to 900-1000ml, soak 4～5 hours, then decoct 80～90 minutes, the filtrate 200ml left and right of removing slag to obtain, medicinal residues add water 200～300ml again, decoct 30～40 minutes, and filtrate 100ml removes slag to obtain, be total to obtain 300ml left and right medicine juice, make the white Colophonium core of trifoliate orange soup, pack in aseptic vial, seal bottle cap is standby, 1 dose minute every day 2 times is oral, each (medicine) being taken before meal 150ml.Combined with Exercise Therapy simultaneously, abdominal crunch every day 1-2 time, 10-20 minute, carries out for 1-2 hour after meal at every turn, and the white Colophonium core of oral trifoliate orange soup 15 days is a course for the treatment of, and rest 3-5 day carries out next course for the treatment of again, general 3 courses for the treatment of.
Principal agent Fructus Aurantii chemistry of the present invention becomes sour orange peel containing volatile oil and flavones ingredient.Citrus aurantium Linn. decoct is in vitro and have remarkable excitation in this uterus to rabbit, can make strength of uterine contraction, tensity increase, and even occurs that tetanic property shrinks.Gastric fistula chronic experiment and intestinal fistula chronic experiment proof has certain excitation to the complete gastrointestinal motility of body, can make gastrointestinal motility shrink that the rhythm and pace of moving things strengthens and strong.Nature and flavor are bitter, pungent, acid temperature, return spleen, stomach warp.There is regulating the flow of QI to ease the stomach, the stagnant relieving distension effect of row, for the breast side of body, the stagnation of QI, distension pain, accumulation of food in the stomach and intes tine due to indigestion, stops in phlegm retention; Gastroptosis, proctoptosis, uterine prolapse.Fructus Aurantii Immaturus nature and flavor are bitter, pungent, sour, warm, return spleen, stomach warp.Have dispelling the stagnated QI removing food stagnancy, the painful abdominal mass effect that disappears of reducing phlegm is stopped in stagnant, and feeling of fullness distending pain is heavy after dysentery, constipation, the stagnant vapour lock breast of expectorant, blocked-up chest, gastroptosis, proctoptosis, uterine prolapse.Semen Lablab Album nature and flavor are sweet, tepor is returned spleen, stomach warp.Have invigorating the spleen for eliminating dampness and in the effect of relieving summer heat, for weakness of the spleen and stomach, inappetence, diarrhea, leukorrhagia, heat-damp in summer is vomited and diarrhoea, abdominal distention uncomfortable in chest.Rhizoma Atractylodis Macrocephalae nature and flavor are bitter, sweet, warm, return spleen, stomach warp.There is invigorating the spleen and benefiting QI, dampness diuretic, hidroschesis, antiabortive effect.For insufficiency of the spleen lack of appetite, abdominal distention is had loose bowels, phlegm retention vertigo and palpitation, edema, spontaneous perspiration, frequent fetal movement.Radix Astragali Mongolici (processed) nature and flavor are sweet, warm, return lung, spleen channel.There is QI invigorating invigorating middle warmer effect, weak for the deficiency of vital energy, anorexia and loose stool.Rhizoma Polygonati nature and flavor are sweet, put down, return spleen, lung, stomach warp.There is boosting qi and nourishing yin, spleen invigorating, lung moistening, kidney tonifying effect.For weakness of the spleen and stomach, fatigue and asthenia, xerostomia lack of appetite, deficiency of the lung cough caused by dryness, asthenia of essence and blood, interior-heat is thirsty clearly.Lignum Dalbergiae Odoriferae nature and flavor are pungent, warm, return liver, spleen channel, have promoting flow of QI and blood, pain relieving, hemostasia effect, and for epigastric pain, hypochondriac pain due to stagnation of liverQI, the stabbing pain of chest and spleen, traumatic injury, traumatic hemorrhage.Pungent, the micro-hardship of Rhizoma Cyperi nature and flavor, micro-sweet, flat.Return liver, spleen, tri-jiao channel.There are promoting QI circulation for relieving depression, menstruction regulating and pain relieving effect, for stagnation of QI due to depression of the liver, breast, the side of body, abdominal distention, dyspepsia, breast gastral cavity painful abdominal mass is vexed, colic of cold type stomachache, distending pain of the breast, menoxenia, amenorrhea dysmenorrhea.Radix Inulae nature and flavor acrid, bitter, warm, returns liver, spleen channel.There is invigorating the spleen and regulating the stomach, promoting the flow of QI for relieving the stagnancy, the antiabortive effect of pain relieving, for the breast side of body, abdominal distention, vomiting dysentery, the breast side of body is dampened, and feels a pain in the chest when breathing and has a pain, frequent fetal movement.Flos Caryophylli nature and flavor are pungent, warm, return spleen, stomach, lung, kidney channel.There is warming middle-JIAO to send down the adverse QI, reinforcing the kidney and supporting YANG effect.For Deficiency and coldness of spleen and stomach, singultus vomiting, lack of appetite and vomiting, trusted subordinate's cold type of pain, impotence due to deficiency of the kidney.Semen Platycladi nature and flavor are sweet, flat, GUIXIN, kidney, large intestine channel.Have tranquilizing by nourishing the heart, hidroschesis, intestine moistening effect, for fidgets due to deficiency insomnia, severe palpitation, night sweat due to yin deficiency, dryness of the intestine constipation.Rhizoma Picrorhizae nature and flavor are bitter, cold, return liver, stomach, large intestine channel.There is clearing away damp-heat, except hectic fever due to YIN-deficiency, the infantile malnutrition with fever effect that disappears, for damp-heat dysentery, jaundice, hemorrhoid expectorant, osteopyrexia and fever etc.Rhizoma Cimicifugae nature and flavor are pungent, micro-sweet, be slightly cold, return lung, spleen, stomach, large intestine channel.There is the rash of delivering, clearing away summer-heat, elevate a turnable ladder yang-energy effect, for headache due to pathogenic wind-heat, toothache, aphtha, laryngopharynx swelling and pain, measles without adequate eruption, YANG toxin syndrome is sent out speckle, proctoptosis, uterine prolapse.Rhizoma Zingiberis Recens nature and flavor are pungent, tepor, return lung, spleen, stomach warp.There is the cold expelling of inducing sweat, warming middle-JIAO to arrest vomiting, preventing phlegm from forming and stopping coughing effect, for anemofrigid cold, gastrofrigid vomiting, cold-phlegm cough.Rhizoma Corydalis comet nature and flavor acrid, bitter, warm, returns liver, spleen channel.There is the promoting the circulation of QI of invigorating blood circulation pain relieving effect, for the breast side of body, epigastric pain, amenorrhea dysmenorrhea, produces stasis blocking, treating swelling and pain by traumatic injury.Fructus Evodiae nature and flavor are pungent, bitter, hot, slightly poisonous, return liver, spleen, stomach, kidney channel.There is dispersing cold for relieving pain, stopping nausea and vomiting by lowering the adverse flow of QI, supporing yang antidiarrheal efficacy.For Que Yin headache, colic of cold type stomachache, the disturbance of lower legs due to pathogenic cold and dampness, abdominal pain during menstruation, abdominal distention, vomiting acid regurgitation, just more has loose bowels etc.Radix Glycyrrhizae Preparata nature and flavor are sweet, flat, GUIXIN, lung, spleen, stomach warp.There is spleen reinforcing stomach function regulating, Yiqi and vein recovery effect.For weakness of the spleen and stomach, fatigue and weakness, severe palpitation, irregularly intermittent and regularly intermittent pulse.Arillus Longan nature and flavor are sweet, warm, GUIXIN spleen channel.There is invigorating the heart and spleen, nourishing blood to tranquillize the mind effect.For insufficiency of vital energy and blood, severe palpitation, forgetful insomnia, blood deficiency and yellow complexion.The ingenious prescription of 18 taste Chinese herbal medicine, reasonable compatibility, medicine mutual-assistance compatibility, accessory drugs can improve principal agent effect; Mutual reinforcement between compatibility, improves performance, effect same medicine curative effect; Mutual restraint between two drugs compatibility, makes its poisonous side effect of medicine alleviate or disappear.The mutual coordinative role of medicine, the specially good effect of playing altogether gastroptosis.
The embodiment that each raw material of the present invention also can the listed ratio of according to the form below (percentage by weight) mixes realizes, and its processing technique is identical with embodiment 1
Below in conjunction with my institute, the clinical trial that Wendeng City, In Shandong Weihai central hospital carries out is done further, is described in detail the present invention:
1, case selection: selected case, all in conjunction with clinical symptoms sign, checks and is defined as gastroptosis patient through x-ray gastrointestinal drink meal, belongs to the traditional Chinese medical science " stomach is slow " category 66 examples, male 27 examples, female's 39 examples; Age 32 was to 59 years old; Early stage 29 examples, mid-terms 23 example, late periods 14 example.
2, Therapeutic Method: 1 dose minute every day 2 times is oral, sooner or later each once, each (medicine) being taken before meal 150ml.Combined with Exercise Therapy simultaneously, abdominal crunch every day 1-2 time, 10-20 minute, carries out for 1-2 hour after meal at every turn, and the white Colophonium core of oral trifoliate orange soup 15 days is a course for the treatment of, and rest 3-5 day carries out next course for the treatment of again, treats 3 courses for the treatment of.
3, therapeutic evaluation:
Recovery from illness: clinical symptoms sign disappears, x-ray check: under stomach, the utmost point gos up to normal position.
Effective: clinical symptoms sign obviously alleviates, x-ray check: under stomach, the utmost point gos up more than 4 centimetres.
Effective: clinical symptoms sign alleviates, x-ray check: under stomach, the utmost point gos up more than 1 centimetre.
Invalid: clinical symptoms sign is without improvement, and under x-ray check stomach, utmost point position is without change.
4, therapeutic effect: use the present invention's 66 examples, treat 3 courses for the treatment of, application the standard of curative effect evaluation carries out treatment effectiveness evaluation: recovery from illness 18 examples; Effective 29 examples; Effective 10 examples; No effect 9, total effective rate is 86.4%.
Claims (1)
1. the white Colophonium core of the trifoliate orange for a gastroptosis soup, it is characterized in that: adopt Fructus Aurantii, Fructus Aurantii Immaturus, Semen Lablab Album, the Rhizoma Atractylodis Macrocephalae, Radix Astragali Mongolici (processed), Rhizoma Polygonati, Lignum Dalbergiae Odoriferae, Rhizoma Cyperi, Radix Inulae, Flos Caryophylli, Semen Platycladi, Rhizoma Picrorhizae, Rhizoma Cimicifugae, Rhizoma Zingiberis Recens, Rhizoma Corydalis, Fructus Evodiae, Radix Glycyrrhizae Preparata, Arillus Longan is crude drug, be soaked in water, the filtrate of removing slag after decocting to obtain, the percentage by weight that crude drug forms is counted, Fructus Aurantii 5～8%, Fructus Aurantii Immaturus 5～8%, Semen Lablab Album 7～10%, the Rhizoma Atractylodis Macrocephalae 4～6%, Radix Astragali Mongolici (processed) 12～16%, Rhizoma Polygonati 4～6%, Lignum Dalbergiae Odoriferae 6～9%, Rhizoma Cyperi 2～5%, Radix Inulae 2～4%, Flos Caryophylli 1～3%, Semen Platycladi 2～5%, Rhizoma Picrorhizae 4～7%, Rhizoma Cimicifugae 4～6%, Rhizoma Zingiberis Recens 4～6%, Rhizoma Corydalis 5～8%, Fructus Evodiae 1～3%, Radix Glycyrrhizae Preparata 4～7%, Arillus Longan 5～8%.
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