CN105535351A - Traditional Chinese medicine for treating endometriosis - Google Patents
Traditional Chinese medicine for treating endometriosis Download PDFInfo
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Abstract
The invention belongs to the technical field of medicines and in particular relates to a traditional Chinese medicine for treating endometriosis. The traditional Chinese medicine is prepared from the following traditional Chinese medicines in parts by weight: 8 to 16 parts of roots of crossostephium chinense (L.) makino, 5 to 13 parts of cinnamomum parthenoxylon, 8 to 16 parts of semen platycladi, 8 to 16 parts of wilson begonia rhizome, 8 to 16 parts of cyperus tuberosus rottb, 8 to 16 parts of flos caryophylli, 8 to 16 parts of ficus esquiroliana, 5 to 13 parts of Sichuan cortex cinnamomi, 5 to 13 parts of clerodendrum bungei roots, 5 to 13 parts of caulis sargentodoxae, 11 to 19 parts of herba cyperi micheliani and 4 to 8 parts of beechey fig leaves. All the medicines are combined to have the effects of warming Chong and Ren meridians, tonifying qi and activating blood, dispelling cold and tonifying spleen, reducing phlegm and resolving stasis and activating meridians to stop pain. The traditional Chinese medicine is used for treating the endometriosis and has the advantage of high total effective rate.
Description
Technical field
The invention belongs to medical art, be specifically related to a kind of Chinese medicine for the treatment of endometriosis.
Background technology
Endometriosis is that this sick sickness rate is in rising trend and the course of disease is long with pelvic pain and the infertile persistence pathological changes for feature, and touching difficulty more.Though be benign lesion, there is the ability of malignant tumor metastasis and plantation growth, therefore one of focal disease becoming modern medicine study.
Summary of the invention
Technical problem to be solved by this invention is the weak point avoided existing for prior art, provides a kind of Chinese medicine for the treatment of endometriosis.
The present invention is achieved through the following technical solutions:
Treat a Chinese medicine for endometriosis, be made up of the Chinese medicine of following weight portion:
Radix Crossostephii Chinensis 8-16 part, Cinnamomum porrectum (Roxb.) Kosterm. 5-13 part, Semen Platycladi 8-16 part, Rhizoma Begoniae Willsonii 8-16 part, false Rhizoma Cyperi 8-16 part, Flos Caryophylli 8-16 part, Ficus fulva Reinw. 8-16 part, river Cortex cinnamomi japonici (Ramulus Cinnamomi) 5-13 part, Radix clerodendri bungei 5-13 part, Caulis mucunae Macrocarpae 5-13 part, Cyperus michelianus(L.) Link (Herba Cyperi Micheliani) 11-19 part, Caulis et Folium Fici beecheyanae 4-8 part.
Preferably, the Chinese medicine of above-mentioned treatment endometriosis, is made up of the Chinese medicine of following weight portion:
Radix Crossostephii Chinensis 10-14 part, Cinnamomum porrectum (Roxb.) Kosterm. 7-11 part, Semen Platycladi 10-14 part, Rhizoma Begoniae Willsonii 10-14 part, false Rhizoma Cyperi 10-14 part, Flos Caryophylli 10-14 part, Ficus fulva Reinw. 10-14 part, river Cortex cinnamomi japonici (Ramulus Cinnamomi) 7-11 part, Radix clerodendri bungei 7-11 part, Caulis mucunae Macrocarpae 7-11 part, Cyperus michelianus(L.) Link (Herba Cyperi Micheliani) 13-17 part, Caulis et Folium Fici beecheyanae 5-7 part.
Preferred, the Chinese medicine of above-mentioned treatment endometriosis, is made up of the Chinese medicine of following weight portion:
Radix Crossostephii Chinensis 12 parts, Cinnamomum porrectum (Roxb.) Kosterm. 9 parts, Semen Platycladi 12 parts, Rhizoma Begoniae Willsonii 12 parts, false Rhizoma Cyperi 12 parts, Flos Caryophylli 12 parts, Ficus fulva Reinw. 12 parts, 9 parts, river Cortex cinnamomi japonici (Ramulus Cinnamomi), Radix clerodendri bungei 9 parts, Caulis mucunae Macrocarpae 9 parts, Cyperus michelianus(L.) Link (Herba Cyperi Micheliani) 15 parts, Caulis et Folium Fici beecheyanae 6 parts.
The Chinese medicine of above-mentioned treatment endometriosis, the dosage form of described Chinese medicine is oral formulations.
The ratio of above weight proportion is through that science screening obtains, and for especial patient, as serious symptom or mild, fat or modest patient, can the proportioning of amount of corresponding adjustment composition, and increase or reduce being no more than 100%, drug effect is substantially constant.
The weight portion of said medicine, if in units of g, the normally consumption of 1 dose.
The taboo item of medicine of the present invention: the fasting for the treatment of period in a medicine is greasy, raw and cold, the smelling of fish or mutton, irritant and stodgy food.
In each component of Chinese medicine for the treatment of endometriosis of the present invention:
Radix Crossostephii Chinensis is the root of feverfew Hibisci Mutabilis chrysanthemum Crossostephiumchinense (L.) Mak.ExCham.EtSchltr..Acrid in the mouth; Bitter; Slightly warm in nature.Function dispels dehumidifying; Warming middle-JIAO to relieve pain.Main air pain of dampness syndrome; Neck abdomen cold type of pain.
Cinnamomum porrectum (Roxb.) Kosterm. another name Lignum cinnamomi camphorae, Pericarpium Zanthoxyli, Cinnamomum langepaniculatum, great Ye Camphor tree, smelly Camphor tree, Borneolum Syntheticum tree.For canella Cinnamomum porrectum (Roxb.) Kosterm. Cinnamomumporrectum (Poxb.) Kosterm. [LaurusporrectaRoxb.; Cinnamomumparthenoxylum (Jack) Nees] root, bark or leaf.Acrid in the mouth; Micro-hardship; Warm in nature.Return lung; Spleen; Liver Channel.Function expelling wind and cold; Warming middle-JIAO to relieve pain; Promoting flow of QI and blood.Main anemofrigid cold; Rheumatic arthralgia; Cold syndrome of the stomach is suffered from abdominal pain; Have loose bowels; Dysentery; Traumatic injury; Menoxenia.
Rhizoma Begoniae Willsonii another name Rhizoma Begoniae Willsonii grass, Herba Duchesneae Indicae, drum-shaped stone blocks, Wei Shi Flos Begoniae Evansianae are the rhizome of Begoniaceae plant Rhizoma Begoniae Willsonii Flos Begoniae Evansianae BegoniawilsoniiGagn..Sweet in the mouth; Bitter; Cold nature.Function nourishes blood and enriches blood; Eliminating stasis to stop pain.Main weak after being ill; Impairment caused by overstrain; Blood deficiency amenorrhea; Endometriosis; Leucorrhea; Spit blood; Spitting of blood; Epistaxis; Traumatic hemorrhage; Treating swelling and pain by traumatic injury.
False Rhizoma Cyperi is sedge Herba Marisci Umbellati Mariscussumatrensis(Retz.) rhizome of T.Koyama and root.Acrid in the mouth; Warm in nature.Function promoting flow of QI and blood; Menstruction regulating and pain relieving; Expelling wind and removing dampness.Main menoxenia; Endometriosis; Puerperal abdonimal pain; Traumatic injury; Rheumatic arthralgia; Flu.
The Ficus fulva Reinw. another name tiger palm, crow wind, amnesty mother-in-law tree, hair, derive from moraceae plants Ficus fulva Reinw. FicusfulvaReiuw., be used as medicine with root bark.Nature and flavor are sweet, flat.Function invigorating the spleen and benefiting QI, promoting blood circulation by removing wind.Curing mainly deficient qi and blood, uterine prolapse, proctoptosis, edema, rheumatic arthralgia, has loose bowels in loose stool.
River Cortex cinnamomi japonici (Ramulus Cinnamomi) is the bark of canella Cinnamomum mairei Levl. CinnamomummaireiL é vl. [C.argenteumGamble].Acrid in the mouth; Sweet; Warm in nature.Function dispelling cold by warming the meridian; Promoting flow of QI and blood; Pain relieving.Main anemofrigid cold; Stomachache with cool feeling; Dysmenorrhea; Fengshi Guanjie pain; Traumatic injury; Fracture.
Radix clerodendri bungei calls smelly maple root, is the root of dicotyledon medicine Verbenaceae Caulis et folium clerodendri bungei ClerodendronbungeiSteud..Acrid in the mouth is bitter; Warm in nature.Return liver; Spleen; Kidney; Lung meridian.Function circulation of qi promoting spleen invigorating; Expelling wind and removing dampness; Removing toxic substances and promoting subsidence of swelling; Blood pressure lowering.The stagnant abdominal distention of staple food; Dizzy; Hiss and cough; Outer dysentery proctoptosis; Perianal abscess hematochezia; Stranguria with turbid discharge leukorrhagia; Rheumatalgia; Foot gas; Swollen ulcer drug; Dermatitis rhus; Hypertension.
Caulis mucunae Macrocarpae another name Caulis Mucunae Wangii, Caulis Sargentodoxae, Caulis seu Radix Schisandrae Henryi, he good dragon.For leguminous plant long pod mucuna MucunamacrcocarpaWall. [M.castaneaMerr.; M.wangiiHu] old stem.Bitter in the mouth; Puckery; Cool in nature.Enter liver, kidney two warp.Function is enriched blood and is invigorated blood circulation; Clearing away lung-heat and moistening for dryness; Dredge the meridian passage.Main anemia; Have through uncomfortable; Lung-heat type cough; Hemoptysis; Soreness of waist and knee joint; Rheumatic arthralgia; Numb hand and foot; Paralysis.
Cyperus michelianus(L.) Link (Herba Cyperi Micheliani) another name revolves clever dried tuber, revolves squama dried tuber, derives from Cyperaceae Cyperus michelianus(L.) Link (Herba Cyperi Micheliani) Cyperusmichelianus(L.) Link [ScirpusmichelianusL.], with all herbal medicine.Light, pungent, flat.Function circulation of qi promoting regulating menstruation.Cure mainly dysmenorrhea, through row pass the appointed time or January 2 ~ 3 persons.
Caulis et Folium Fici beecheyanae is stem, the leaf of moraceae plants Fructus Fici Beecheyanae.Sweet light, temperature, nontoxic.Enter lung, spleen, kidney three warp.Function invigorating the spleen and replenishing QI, invigorating the spleen for eliminating dampness, bone and muscle strengthening, detumescence, promoting blood circulation and detoxication.Dispelling the wind and dampness pathogens arthralgia, the middle deficiency of vital energy is weak, and QI and blood is on the decline, and extremity are aching and limp, stiffness of the muscle and joint, traumatic injury, amenorrhea, galactostasis.
In medicine of the present invention, other medicines all record in Chinese Pharmacopoeia 2015 editions.
Though name of disease not corresponding with endometriosis in Chinese medicine ancient books and records, the clinical manifestation of this disease similar and sign sporadically appear in the diseases such as dysmenorrhea, menoxenia, infertile, lump in the abdomen.Blood stasis is the key producing endometriosis sings and symptoms, and blood circulation promoting and blood stasis dispelling has become the method that this disease of Chinese medicine shows unique characteristics.In prescriptions of Chinese medicine of the present invention, Radix Crossostephii Chinensis, Cinnamomum porrectum (Roxb.) Kosterm. warming middle-JIAO to relieve pain; River Cortex cinnamomi japonici (Ramulus Cinnamomi) warming the meridian for promoting the flow of YANG QI; Ficus fulva Reinw., Caulis et Folium Fici beecheyanae invigorating middle warmer spleen invigorating; Semen Platycladi, Rhizoma Begoniae Willsonii, false Rhizoma Cyperi, Radix clerodendri bungei, Cyperus michelianus(L.) Link (Herba Cyperi Micheliani) nourish blood and seek, stasis-dispelling and pain-killing, dissipating phlegm and resolving masses; Caulis mucunae Macrocarpae, Flos Caryophylli moisturize sending down the abnormal ascending QI.The merit agent that all medicines share and play that temperature compensation punching is appointed altogether, benefiting QI for activating blood circulation, cold expelling spleen invigorating, dissipating phlegm and resolving masses disappear note of the ancient Chinese, removing obstruction in the collateral to relieve pain.We enrich blood promoting the circulation of blood, tonify without causing stagnation, and invigorating middle warmer has row, very close the normal feature that is not enough, the easily empty easily stasis of blood of woman's blood, with strengthening vital QI to eliminate pathogenic factors; Effective prescription of endometriosis is caused for treating cold blood stasis uterus.
Detailed description of the invention
Below in conjunction with specific embodiment, the present invention is further described, so that those skilled in the art more understands the present invention, but does not therefore limit the present invention.
Embodiment 1
Treat a Chinese medicine for endometriosis, concrete medicine and weight proportion as follows:
Radix Crossostephii Chinensis 12g, Cinnamomum porrectum (Roxb.) Kosterm. 9g, Semen Platycladi 12g, Rhizoma Begoniae Willsonii 12g, false Rhizoma Cyperi 12g, Flos Caryophylli 12g, Ficus fulva Reinw. 12g, river Cortex cinnamomi japonici (Ramulus Cinnamomi) 9g, Radix clerodendri bungei 9g, Caulis mucunae Macrocarpae 9g, Cyperus michelianus(L.) Link (Herba Cyperi Micheliani) 15g, Caulis et Folium Fici beecheyanae 6g.
Embodiment 2
Treat a Chinese medicine for endometriosis, concrete medicine and weight proportion as follows:
Radix Crossostephii Chinensis 10g, Cinnamomum porrectum (Roxb.) Kosterm. 7g, Semen Platycladi 10g, Rhizoma Begoniae Willsonii 10g, false Rhizoma Cyperi 10g, Flos Caryophylli 10g, Ficus fulva Reinw. 10g, river Cortex cinnamomi japonici (Ramulus Cinnamomi) 7g, Radix clerodendri bungei 7g, Caulis mucunae Macrocarpae 7g, Cyperus michelianus(L.) Link (Herba Cyperi Micheliani) 13g, Caulis et Folium Fici beecheyanae 5g.
Embodiment 3
Treat a Chinese medicine for endometriosis, concrete medicine and weight proportion as follows:
Radix Crossostephii Chinensis 14g, Cinnamomum porrectum (Roxb.) Kosterm. 11g, Semen Platycladi 14g, Rhizoma Begoniae Willsonii 14g, false Rhizoma Cyperi 14g, Flos Caryophylli 14g, Ficus fulva Reinw. 14g, river Cortex cinnamomi japonici (Ramulus Cinnamomi) 11g, Radix clerodendri bungei 11g, Caulis mucunae Macrocarpae 11g, Cyperus michelianus(L.) Link (Herba Cyperi Micheliani) 17g, Caulis et Folium Fici beecheyanae 7g.
Embodiment 4
Treat a Chinese medicine for endometriosis, concrete medicine and weight proportion as follows:
Radix Crossostephii Chinensis 8g, Cinnamomum porrectum (Roxb.) Kosterm. 5g, Semen Platycladi 8g, Rhizoma Begoniae Willsonii 8g, false Rhizoma Cyperi 8g, Flos Caryophylli 8g, Ficus fulva Reinw. 8g, river Cortex cinnamomi japonici (Ramulus Cinnamomi) 5g, Radix clerodendri bungei 5g, Caulis mucunae Macrocarpae 5g, Cyperus michelianus(L.) Link (Herba Cyperi Micheliani) 11g, Caulis et Folium Fici beecheyanae 4g.
Embodiment 5
Treat a Chinese medicine for endometriosis, concrete medicine and weight proportion as follows:
Radix Crossostephii Chinensis 16g, Cinnamomum porrectum (Roxb.) Kosterm. 13g, Semen Platycladi 16g, Rhizoma Begoniae Willsonii 16g, false Rhizoma Cyperi 16g, Flos Caryophylli 16g, Ficus fulva Reinw. 16g, river Cortex cinnamomi japonici (Ramulus Cinnamomi) 13g, Radix clerodendri bungei 13g, Caulis mucunae Macrocarpae 13g, Cyperus michelianus(L.) Link (Herba Cyperi Micheliani) 19g, Caulis et Folium Fici beecheyanae 8g.
Carried out clinical pharrnacokinetics test to the Chinese medicine for the treatment of endometriosis of the present invention, Details as Follows:
1 physical data
Endometriosis patients 110 example, is divided into two groups at random.Wherein treatment group 60 example, 28.3 ± 4.8 years old mean age; 16 examples that dysmenorrhea is slight, moderate 28 example, severe 16 example; Infertile 48 examples, sexual anhedonia 25 example, lumbago in menstrual period 30 example; B ultrasonic and gynecologial examination have painful tubercles or chocolate cyst of ovary 35 example.Matched group 50 example, 27.7 ± 5.1 years old age; 14 examples that dysmenorrhea is slight, moderate 24 example, severe 12 example; Infertile 38 examples, sexual anhedonia 3O example, lumbago in menstrual period 40 example; B ultrasonic and gynecologial examination have painful tubercles or chocolate cyst of ovary 30 example.Two groups of physical data there was no significant differences (P>O.05), have comparability.
2 Therapeutic Method
Two groups all from menstruation the 1st day, daily mifepristone (production of Hua Lian, Shanghai pharmaceutical factory) 12.5mg, serve on 3 months.Treatment group gives the Chinese medicine of the embodiment of the present invention 1, every day 1 dose, decocting 2 times.Medicine juice is concentrated into 200ml after filtration.Point early, evening takes for 2 times, 3 months courses for the treatment of.Treat after 3 months and carry out gynecologial examination and B ultrasonic check respectively, and monitor follicular development and situation of becoming pregnant, carry out Evaluation of Synthetic Effect of Holistic.
3 therapeutic outcomes
3.1 criterions of therapeutical effect: with reference to " diagnostic criteria of endometriosis curative effect (the tentative draft) " of the 3rd the academic conference revision of department of obstetrics and gynecology Professional Committee of CAIM (Chinese Association Of Integrative Medicine).Recovery from illness: symptom all disappears, and pelvic lump disappears substantially, infertility person is gestation or fertility in 2 years; Effective: symptom disappears substantially, pelvic lump reduces, and infertility person is become pregnant; Effective: symptom alleviates, pelvic lump is without increase or slightly reduce, and in drug withdrawal 3 months, symptom does not increase the weight of; Invalid: cardinal symptom is unchanged, local patholoic change has and increases the weight of trend.Pelvic lump ultrasound diagnosis all contrasts with menstrual cycle.To the person of recovering, drug withdrawal was followed up a case by regular visits to after 3 months, again occurred that symptom and sign person are recurrence.
3.2 liang of group comparitive study: treatment group is fully recovered 28 examples (46.67%), effective l7 example (28.33%), effective 11 examples (18.33%), invalid 4 examples (6.67%), total effective rate 93.33%; Matched group is fully recovered 10 examples (20.00%), effective 12 examples (24.00%), effective 13 examples (26.00%), invalid 15 examples (30.00%), total effective rate 70.00%.Treatment group curative effect is better than matched group (P<0.05).Follow up a case by regular visits to after 1 year, treatment group recurrence 6 example, in 48 routine infertile persons, have 29 example gestation; Matched group recurrence 11 example, has 15 example gestation in 38 routine infertile persons.Two groups all without obvious hepatic and renal function injure and other untoward reaction.
Claims (3)
1. treat a Chinese medicine for endometriosis, be made up of the Chinese medicine of following weight portion:
Radix Crossostephii Chinensis 8-16 part, Cinnamomum porrectum (Roxb.) Kosterm. 5-13 part, Semen Platycladi 8-16 part, Rhizoma Begoniae Willsonii 8-16 part, false Rhizoma Cyperi 8-16 part, Flos Caryophylli 8-16 part, Ficus fulva Reinw. 8-16 part, river Cortex cinnamomi japonici (Ramulus Cinnamomi) 5-13 part, Radix clerodendri bungei 5-13 part, Caulis mucunae Macrocarpae 5-13 part, Cyperus michelianus(L.) Link (Herba Cyperi Micheliani) 11-19 part, Caulis et Folium Fici beecheyanae 4-8 part.
2. the Chinese medicine for the treatment of endometriosis according to claim 1, is characterized in that, is made up of the Chinese medicine of following weight portion:
Radix Crossostephii Chinensis 10-14 part, Cinnamomum porrectum (Roxb.) Kosterm. 7-11 part, Semen Platycladi 10-14 part, Rhizoma Begoniae Willsonii 10-14 part, false Rhizoma Cyperi 10-14 part, Flos Caryophylli 10-14 part, Ficus fulva Reinw. 10-14 part, river Cortex cinnamomi japonici (Ramulus Cinnamomi) 7-11 part, Radix clerodendri bungei 7-11 part, Caulis mucunae Macrocarpae 7-11 part, Cyperus michelianus(L.) Link (Herba Cyperi Micheliani) 13-17 part, Caulis et Folium Fici beecheyanae 5-7 part.
3. the Chinese medicine for the treatment of endometriosis according to claim 3, is characterized in that, is made up of the Chinese medicine of following weight portion:
Radix Crossostephii Chinensis 12 parts, Cinnamomum porrectum (Roxb.) Kosterm. 9 parts, Semen Platycladi 12 parts, Rhizoma Begoniae Willsonii 12 parts, false Rhizoma Cyperi 12 parts, Flos Caryophylli 12 parts, Ficus fulva Reinw. 12 parts, 9 parts, river Cortex cinnamomi japonici (Ramulus Cinnamomi), Radix clerodendri bungei 9 parts, Caulis mucunae Macrocarpae 9 parts, Cyperus michelianus(L.) Link (Herba Cyperi Micheliani) 15 parts, Caulis et Folium Fici beecheyanae 6 parts.
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Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102423480A (en) * | 2011-12-09 | 2012-04-25 | 崔皓 | Trifoliate orange/rhizoma atractylodis macrocephalae/rhizoma polygonati/rhizoma cyperi/shelled cedar seed soup for gastroptosis |
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2016
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN102423480A (en) * | 2011-12-09 | 2012-04-25 | 崔皓 | Trifoliate orange/rhizoma atractylodis macrocephalae/rhizoma polygonati/rhizoma cyperi/shelled cedar seed soup for gastroptosis |
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Application publication date: 20160504 |