CN102335288A - Giant salamander skin mucus scalding ointment - Google Patents
Giant salamander skin mucus scalding ointment Download PDFInfo
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- CN102335288A CN102335288A CN2010102384154A CN201010238415A CN102335288A CN 102335288 A CN102335288 A CN 102335288A CN 2010102384154 A CN2010102384154 A CN 2010102384154A CN 201010238415 A CN201010238415 A CN 201010238415A CN 102335288 A CN102335288 A CN 102335288A
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Abstract
The invention discloses scalding ointment prepared from giant salamander skin mucus. A method for preparing the scalding ointment comprises the following steps of: collecting the giant salamander skin mucus in a giant salamander artificial cultivation pond, performing freeze drying under vacuum, and crushing to form 120-mesh mucus powder; crushing rhubarb and giant knotweed rhizome in the ratio of 1:1 to form 80-mesh powder, adding water in an amount which is 30 times that of the powder, and leaching at the temperature of 85 DEG C for 2 hours; and leaching 15 percent of mucus powder and 30 percent of leach liquor at the temperature of 65 DEG C for 1 hour, adding 20 percent of mixed oil (tea seed oil, tung oil and sesame oil in the ratio of 3:2:1), 5 percent of borneol, 10 percent of honey, 20 percent of vaseline and 0.5 percent of cinnamyl aldehyde, and mixing uniformly to form the ointment. The ointment is applied to scalding surfaces to increase collagen, amino acid, natural hormone, vitamins, saccharides, mineral substances and other active substances of wounds, has the effects of resisting bacteria and oxidation, preserving moisture, diminishing inflammation, relieving pain, promoting cell proliferation, accelerating wound healing and the like, and has the characteristics of quick healing of the scalding surfaces and no scars after being used.
Description
Technical field
The present invention relates to the compound method of Andrias davidianus Blanchard skin mucus Scald Ointment, particularly with Andrias davidianus Blanchard skin mucus, Radix Et Rhizoma Rhei, Rhizoma Polygoni Cuspidati extract, miscella and other composition preparation scald ointment.
Background technology
Andrias davidianus Blanchard (Andrias davidianus Blanchard) popular name " frog WAYU " belongs to Amphibia, Caudata, Cryptobranchidae, belongs to national secondary and watches for animals.Andrias davidianus Blanchard in the artificial cultivation process, after Andrias davidianus Blanchard skin mucilage cell discharges mucus, combine with water mucus; Cover the epithelium free surface, formed natural guard system one, the skin mucus can come off and float in water; Collect utilization effective ingredient wherein, the development ointment for scald.Andrias davidianus Blanchard skin mucus contains polysaccharide albumen, Magainin, Squalene, cholestene-alcohol compound, has stronger antibacterial action, promotes the cell growth, effects such as treatment scald, beauty treatment.Among the people with Andrias davidianus Blanchard skin dry the back pulverize, Oleum Verniciae fordii accents spread on the scald injury, a week can fully recover.
In existing treatment of scald, the conventional Chinese medicine dosage form has: oil preparation such as Oleum Radix Arnebiae (Oleum Radix Lithospermi), Adeps melis etc.; Unguentum such as ointment for treating burn, Scald Ointment etc.; Powder is as scalding gunpowder, single Rhizoma Polygoni Cuspidati powder etc.; Membrane is like burn medicine film; The new drop of aqueous solvent such as rehabilitation, compound recipe bear bile fluid etc.; Spray is like the spirit of burning, the SHAOSHANG PENWUJI.The main component of scalding medicine has Radix Sanguisorbae, Radix Sanguisorbae, purple leather, Rhizoma Coptidis, Rhizoma Polygoni Cuspidati, Olibanum, Myrrha, Radix Et Rhizoma Rhei, Borneolum Syntheticum, the Radix Angelicae Dahuricae, has heat-clearing and toxic substances removing, blood circulation promoting and blood stasis dispelling, detumescence and promoting granulation effect, and the Radix Angelicae Dahuricae has the alleviating pain and detumescence effect.Do not see with document and the product of Andrias davidianus Blanchard skin mucus with Radix Et Rhizoma Rhei, the relevant composition mixed preparing of Rhizoma Polygoni Cuspidati extract ointment for scald.
Summary of the invention
Andrias davidianus Blanchard skin mucus ointment for scald of the present invention; With Andrias davidianus Blanchard skin mucus, miscella (tea-seed oil, Oleum Verniciae fordii, Oleum sesami; Ratio is 3: 2: 1), Radix Et Rhizoma Rhei, Rhizoma Polygoni Cuspidati ratio 1: 1, and be equipped with Borneolum Syntheticum, Mel, vaseline, cinnamic aldehyde, prepare ointment according to a certain percentage.Utilize compositions promotion cell growths such as Magainin, Squalene, cholestene, collagen protein in the Andrias davidianus Blanchard mucus, the healing of accelerated in wounds.Emodin, chrysophanic acid have effects such as stronger antibacterial action and good is invigorated blood circulation, brought down a fever, antiinflammatory in the Radix Et Rhizoma Rhei; Rhizoma Polygoni Cuspidati has the effect of heat-clearing and toxic substances removing, putrefaction removing, granulation promoting, convergence pain relieving.Compositions such as unsaturated fatty acid, vitamin E, tea polyphenols promote the cell growth in the tea-seed oil, and Oleum Verniciae fordii prevents xerosis cutis.Contain saccharide in the TUFENGMI; Protein and several amino acids, elements such as ferrum, copper, potassium, sodium, tungsten, manganese, magnesium, phosphorus, silicon, lead, chromium, nickel and cobalt, vitamin B group; Vitamin such as vitamin C, nicotinic acid, pantothenic acid, biotin have easing the pain and promote wound healing; The effect of Cortex Cinnamomi excellent antibiotic, that vaseline has is lubricated, protection skin is in case the effect of crowfoot cracks, Borneolum Syntheticum contain Borneolum Syntheticum, isoborneol, Camphora mouth brain all have antibiotic, the effect of clearing away heat to alleviate pain, granulation promoting.
Therefore, the skin mucus that utilizes artificially-cultured giant salamander to produce, Radix Et Rhizoma Rhei, Rhizoma Polygoni Cuspidati extract, the scald new drug of miscella and the preparation of other composition belongs to initiative both at home and abroad.That Andrias davidianus Blanchard mucus ointment for scald has is antibiotic, antiinflammatory, pain relieving, prevent that tissue fluid from leaching, hemostasis, anti-wound face be dry, promotes Skin Cell division, hypertrophy, accelerating wound healing and reparation, it is remarkable to scald effect for treatment, one thorough more, preventing from scar.
The technical scheme that realizes above-mentioned purpose is:
Below in conjunction with embodiment the present invention is done further detailed explanation.
Examples of implementation
1. Andrias davidianus Blanchard skin mucus is collected: culture factory in the Andrias davidianus Blanchard manual scale, pull mucus out every day from culture the pond, use aseptic water washing, the moisture of leaving away.
2. mucus is dry: through pre-freeze, carry out vacuum lyophilization 48H again.
3. pulverize: adopt super micron mill, be ground into 120 orders.
4. Radix Et Rhizoma Rhei Rhizoma Polygoni Cuspidati lixiviating solution: Radix Et Rhizoma Rhei and Rhizoma Polygoni Cuspidati are ground into 80 orders at 1: 1, add 30 times of water, 85 ℃ of hot dipping 2H.
5. mucolytic: in 15% mucus powder, add 3 times Chinese medicine lixiviating solution, under 60 ℃ of conditions, ultrasonic dissolution 60 minutes grinds and pulls an oar into pasty state.
6. plaster preparation: in mucus is stuck with paste, add honeybee 10%, vaseline 20%, Borneolum Syntheticum 5% stirring, after the cooling, add miscella 20% and cinnamic aldehyde 0.5%, stir.
7. ointment uses: after will scalding the face cleaning and sterilizing earlier, ointment is evenly spread upon wound face.Clean with medical alcohol when changing dressings, smearing ointment is changed dressings 2-3 time again, and a week can heal entirely, preventing from scar.
Claims (4)
1. an Andrias davidianus Blanchard skin mucus Scald Ointment is characterized in that: from giant salamander culture pond, collect mucus, through vacuum lyophilization, pulverizing mucus 120 orders; Radix Et Rhizoma Rhei and Rhizoma Polygoni Cuspidati are ground into 80 orders at 1: 1, add 30 times of water 85 ℃ of lixiviates 2 hours.With 15% mucus powder and 30% lixiviating solution, 65 ℃ of lixiviates 1 hour, (tea-seed oil: Oleum Verniciae fordii: Oleum sesami=3: 2: 1), Borneolum Syntheticum 5%, Mel 10%, vaseline 20%, cinnamic aldehyde 0.5% mixed and process cream to add 20% miscella.
2. according to the described Andrias davidianus Blanchard skin of claim 1 mucus Scald Ointment prescription, it is characterized in that: the Scald Ointment of processing is easy to smear, good film-forming property, and abnormal smells from the patient is strong.
3. according to claim 1 or 2 described Andrias davidianus Blanchard skin mucus Scald Ointments prescription, it is characterized in that: mouthful preserve moisture to scalding, antibiotic, anti-inflammatory analgetic, promotion wound healing.
4. according to the described Andrias davidianus Blanchard skin of claim 1 mucus Scald Ointment prescription, it is characterized in that: scald mouth and be easy to healing, preventing from scar.
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| CN2010102384154A CN102335288A (en) | 2010-07-20 | 2010-07-20 | Giant salamander skin mucus scalding ointment |
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| CN2010102384154A CN102335288A (en) | 2010-07-20 | 2010-07-20 | Giant salamander skin mucus scalding ointment |
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Cited By (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102764273A (en) * | 2012-08-14 | 2012-11-07 | 新疆师范大学 | Method for purifying skin secretions of tailed amphibian ranodon sibiricus and application |
| CN103829235A (en) * | 2014-01-11 | 2014-06-04 | 陕西理工学院 | Preparation method of giant salamander skin mucus whole powder |
| CN103865689A (en) * | 2014-03-06 | 2014-06-18 | 张家界（中国）金驰大鲵生物科技有限公司 | Soap capable of inhibiting mites and preparation method thereof |
| CN104223121A (en) * | 2014-09-16 | 2014-12-24 | 重庆馗旭生物科技股份有限公司 | Extracting device for giant salamander skin mucus and extracting method |
| CN104721882A (en) * | 2015-04-02 | 2015-06-24 | 重庆馗旭生物科技股份有限公司 | Application of giant salamander mucus in preparation of soft tissue filling material |
| CN104740678A (en) * | 2015-04-02 | 2015-07-01 | 重庆馗旭生物科技股份有限公司 | Application of giant salamander mucus in preparation of adhesive |
| CN104758978A (en) * | 2015-04-02 | 2015-07-08 | 重庆馗旭生物科技股份有限公司 | Application of giant salamander mucus in preparation of bleeding-stopping material |
| CN104815349A (en) * | 2015-04-02 | 2015-08-05 | 重庆馗旭生物科技股份有限公司 | Binder prepared from giant salamander mucus and preparation method thereof |
| CN105233271A (en) * | 2015-11-19 | 2016-01-13 | 洛阳师范学院 | Anti-scaring andrias skin collagen burn cream and preparation method thereof |
| CN105287697A (en) * | 2015-10-23 | 2016-02-03 | 陕西龙香堂生物工程股份有限公司 | Andrias davidianus tissue extract compound composition and application thereof |
| CN105999213A (en) * | 2016-06-15 | 2016-10-12 | 通江县光泰科技发展有限责任公司 | Preparation method of giant salamander skin ointment for repairing human skin |
| CN106047968A (en) * | 2016-05-13 | 2016-10-26 | 张家界（中国）金驰大鲵生物科技有限公司 | Giant salamander active peptide and application |
| CN106511399A (en) * | 2016-11-16 | 2017-03-22 | 太鲵生物科技（天津）有限公司 | A use of mucus of andrias davidianus Blanchard |
| CN107281535A (en) * | 2017-08-10 | 2017-10-24 | 魏泓 | Giant salamander secretion viscosity biomembrane and its preparation method and application |
| CN107456599A (en) * | 2017-08-10 | 2017-12-12 | 魏泓 | Antibacterial giant salamander secretion biomembrane and its preparation method and application |
| CN108066369A (en) * | 2016-11-16 | 2018-05-25 | 太鲵生物科技（天津）有限公司 | A kind of preparation method of giant salamander pituitary extract |
| CN108434442A (en) * | 2018-04-24 | 2018-08-24 | 广州赛莱拉干细胞科技股份有限公司 | Include the Wound healing compositions of outstanding wart horse hair algae extract |
| CN114984233A (en) * | 2021-11-05 | 2022-09-02 | 重庆医科大学附属口腔医院 | Local drug delivery system based on giant salamander skin secretion and application thereof |
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| CN101254246A (en) * | 2008-04-03 | 2008-09-03 | 华中科技大学 | External-used burn and scald treating medicine and its preparation |
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Cited By (26)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102764273B (en) * | 2012-08-14 | 2014-05-07 | 新疆师范大学 | Method for purifying skin secretions of tailed amphibian ranodon sibiricus and application |
| CN102764273A (en) * | 2012-08-14 | 2012-11-07 | 新疆师范大学 | Method for purifying skin secretions of tailed amphibian ranodon sibiricus and application |
| CN103829235B (en) * | 2014-01-11 | 2015-07-01 | 陕西理工学院 | Preparation method of giant salamander skin mucus whole powder |
| CN103829235A (en) * | 2014-01-11 | 2014-06-04 | 陕西理工学院 | Preparation method of giant salamander skin mucus whole powder |
| CN103865689A (en) * | 2014-03-06 | 2014-06-18 | 张家界（中国）金驰大鲵生物科技有限公司 | Soap capable of inhibiting mites and preparation method thereof |
| CN104223121A (en) * | 2014-09-16 | 2014-12-24 | 重庆馗旭生物科技股份有限公司 | Extracting device for giant salamander skin mucus and extracting method |
| CN104721882A (en) * | 2015-04-02 | 2015-06-24 | 重庆馗旭生物科技股份有限公司 | Application of giant salamander mucus in preparation of soft tissue filling material |
| CN104740678A (en) * | 2015-04-02 | 2015-07-01 | 重庆馗旭生物科技股份有限公司 | Application of giant salamander mucus in preparation of adhesive |
| CN104758978A (en) * | 2015-04-02 | 2015-07-08 | 重庆馗旭生物科技股份有限公司 | Application of giant salamander mucus in preparation of bleeding-stopping material |
| CN104815349A (en) * | 2015-04-02 | 2015-08-05 | 重庆馗旭生物科技股份有限公司 | Binder prepared from giant salamander mucus and preparation method thereof |
| CN104758978B (en) * | 2015-04-02 | 2017-06-16 | 重庆馗旭生物科技股份有限公司 | Application of the giant salamander mucus in hemostatic material is prepared |
| CN105287697A (en) * | 2015-10-23 | 2016-02-03 | 陕西龙香堂生物工程股份有限公司 | Andrias davidianus tissue extract compound composition and application thereof |
| CN105233271A (en) * | 2015-11-19 | 2016-01-13 | 洛阳师范学院 | Anti-scaring andrias skin collagen burn cream and preparation method thereof |
| CN105233271B (en) * | 2015-11-19 | 2018-08-31 | 洛阳师范学院 | A kind of anti-scar salamander collagen burn cream and preparation method thereof |
| CN106047968A (en) * | 2016-05-13 | 2016-10-26 | 张家界（中国）金驰大鲵生物科技有限公司 | Giant salamander active peptide and application |
| CN106047968B (en) * | 2016-05-13 | 2019-04-16 | 张家界（中国）金驰大鲵生物科技有限公司 | Giant salamander active peptide and purposes |
| CN105999213A (en) * | 2016-06-15 | 2016-10-12 | 通江县光泰科技发展有限责任公司 | Preparation method of giant salamander skin ointment for repairing human skin |
| CN108066369A (en) * | 2016-11-16 | 2018-05-25 | 太鲵生物科技（天津）有限公司 | A kind of preparation method of giant salamander pituitary extract |
| CN106511399A (en) * | 2016-11-16 | 2017-03-22 | 太鲵生物科技（天津）有限公司 | A use of mucus of andrias davidianus Blanchard |
| CN106511399B (en) * | 2016-11-16 | 2023-12-01 | 太鲵生物科技（天津）有限公司 | Application of giant salamander mucus |
| CN107456599A (en) * | 2017-08-10 | 2017-12-12 | 魏泓 | Antibacterial giant salamander secretion biomembrane and its preparation method and application |
| CN107281535A (en) * | 2017-08-10 | 2017-10-24 | 魏泓 | Giant salamander secretion viscosity biomembrane and its preparation method and application |
| CN107456599B (en) * | 2017-08-10 | 2020-09-01 | 魏泓 | Antibacterial giant salamander secretion biomembrane and preparation method and application thereof |
| CN108434442A (en) * | 2018-04-24 | 2018-08-24 | 广州赛莱拉干细胞科技股份有限公司 | Include the Wound healing compositions of outstanding wart horse hair algae extract |
| CN114984233A (en) * | 2021-11-05 | 2022-09-02 | 重庆医科大学附属口腔医院 | Local drug delivery system based on giant salamander skin secretion and application thereof |
| CN114984233B (en) * | 2021-11-05 | 2023-07-14 | 重庆医科大学附属口腔医院 | Local drug delivery system based on giant salamander skin secretion and application thereof |
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Application publication date: 20120201 |