CN102302550B - Medicament for treating coronary heart disease - Google Patents

Medicament for treating coronary heart disease Download PDF

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CN102302550B
CN102302550B CN 201110273370 CN201110273370A CN102302550B CN 102302550 B CN102302550 B CN 102302550B CN 201110273370 CN201110273370 CN 201110273370 CN 201110273370 A CN201110273370 A CN 201110273370A CN 102302550 B CN102302550 B CN 102302550B
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parts
medicine
blood
heart disease
coronary heart
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CN102302550A (en
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黄文龙
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Abstract

The invention discloses a medicament for treating coronary heart disease. The medicament is prepared from the following raw material drugs in parts by weight: 20 to 30 parts of gingko leaves, 15 to 25 parts of root of red-rooted salvia, 10 to 15 parts of hemlock parsley, 10 to 15 parts of safflower, and 10 to 15 parts of pseudo-ginseng. The medicament has mild medicine property, quick acting, stable curative effect, safety and no toxic or side effect, and recurrence rate of the coronary heart disease is low; the medicament can be used for regulating heart functions and improving myocardial blood oxygen supply state, and has the functions of effectively dredging heart-blood stagnation, tonifying heart and astringing lungs, eliminating dampness, softening blood vessels, reducing blood fat, regulating blood pressure, nourishing the blood and tranquilization, regulating vital energy to alleviate mental depression, and eliminating blood stasis for analgesic and the like.

Description

A kind of medicine for the treatment of coronary heart disease
Technical field
The present invention relates to the field of Chinese medicines, particularly a kind of medicine for the treatment of coronary heart disease.
Background technology
Coronary heart disease is disease common in the mid-aged population, mostly is to cause owing to coronary atherosclerosis causes in various degree myocardial ischemia, ischemia.Wherein in the majority with type of obstruction of heart-blood, other disease types also all easily cause or are mingled with stagnation of heart-blood, the probability of the diseases such as middle-aged and elderly people trouble hypertension, hyperlipidemia, hyperglycemia is increasing at present, and this is again arteriosclerosis, narrow, blood viscosity increases, velocity of blood flow is slowed down, the first cause of last stasis blocking.
Patients with coronary heart disease take uncomfortable in chest, breathe hard pant, cardiopalmus, palpitation with a distress feeling is as primary symptom, and is serious also with angina pectoris, can cause sudden death.Incidence of CHD is high, and mortality is high, and the serious harm mankind's is healthy.
The drug kinds for the treatment of coronary heart disease is various, mostly adopts western medicine.But general Therapeutic Method is the medicine that adopts coronary dilating and decreased heart rate, improves myocardial oxygen delivery and reduces myocardial oxygen consumption, thereby alleviate state of an illness symptom.Facts have proved, though this class medicine can be alleviated disease to a certain extent, exist all the time the adverse consequencess such as impairment of YIN, consumption gas, the purpose of difficult Da Zhiben.Normally the state of an illness is relaxed during the medication, in case the just again recovery of the drug withdrawal state of an illness, and inappropriate medication, the possibility of failing to respond to any medical treatment in addition, even can cause disease to increase the weight of.
Summary of the invention
The purpose of this invention is to provide a kind of safe and reliable, the medicine that can effectively treat various type disease coronary heart disease, the property of medicine of this medicine is gentle, stable curative effect, and relapse rate is low.
Drug main of the present invention will be selected the natural Chinese medicinal herb such as Folium Ginkgo, Radix Salviae Miltiorrhizae, Rhizoma Chuanxiong, Flos Carthami and Radix Notoginseng, through the science compatibility, makes the effect of each medicine produce good synergism, thereby effectively treats coronary heart disease.
Technical scheme of the present invention is:
A kind of medicine for the treatment of coronary heart disease, made by the crude drug of following weight portion:
20-30 parts of Folium Ginkgos, 15-25 parts of Radix Salviae Miltiorrhizaes, 10-15 parts of Rhizoma Chuanxiongs, 10-15 parts on Flos Carthami, 10-15 parts in Radix Notoginseng.
Be preferably following five kinds of proportionings:
1,25 parts of Folium Ginkgos, 20 parts of Radix Salviae Miltiorrhizaes, 10 parts of Rhizoma Chuanxiongs, 10 parts on Flos Carthami, 10 parts in Radix Notoginseng.
2,25 parts of Folium Ginkgos, 20 parts of Radix Salviae Miltiorrhizaes, 15 parts of Rhizoma Chuanxiongs, 15 parts on Flos Carthami, 15 parts in Radix Notoginseng.
3,20 parts of Folium Ginkgos, 15 parts of Radix Salviae Miltiorrhizaes, 10 parts of Rhizoma Chuanxiongs, 10 parts on Flos Carthami, 10 parts in Radix Notoginseng.
4,30 parts of Folium Ginkgos, 25 parts of Radix Salviae Miltiorrhizaes, 15 parts of Rhizoma Chuanxiongs, 15 parts on Flos Carthami, 15 parts in Radix Notoginseng.
5,25 parts of Folium Ginkgos, 20 parts of Radix Salviae Miltiorrhizaes, 12 parts of Rhizoma Chuanxiongs, 12 parts on Flos Carthami, 12 parts in Radix Notoginseng.
Medicine of the present invention can adopt the conventional method of Chinese medicine preparation, is prepared into any conventional oral preparations.After for example the medicine material of percentage by weight of the present invention being mixed, processes is made routinely comprises the pharmaceutical preparatioies such as drop pill, capsule, soft capsule, tablet, granule, powder and oral liquid.
As monarch drug, the Folium Ginkgo benefit heart is astringed the lung with Folium Ginkgo for medicine of the present invention, removing dampness, and uncomfortable in chest to treating, pained, cardiopalmus, phlegm dyspnea cough have good effect, and can vessel softening, blood fat reducing, regulates blood pressure; As the second monarch drug, rule together Radix Salviae Miltiorrhizae blood circulation promoting and blood stasis dispelling, nourishing blood to tranquillize the mind with the Folium Ginkgo cardiopulmonary that complement each other with Radix Salviae Miltiorrhizae; Adapted Rhizoma Chuanxiong, Flos Carthami and Radix Notoginseng are ministerial drug, Rhizoma Chuanxiong temperature promoting blood circulation, activating QI to alleviate the depression; Blood stasis in the carthamus powder meridians; Radix Notoginseng blood stasis dispelling analgesic therapy.
Medicament composing prescription uniqueness of the present invention, refine, specific aim are extremely strong.Long-term application curative effect proves: this medicine can be regulated cardiac function, improves myocardium blood oxygen supply situation, the dredging stagnation of heart-blood, and the beneficial heart is astringed the lung, removing dampness, vessel softening, blood fat reducing, adjusting blood pressure, nourishing blood to tranquillize the mind, activating QI to alleviate the depression, the blood stasis dispelling analgesic therapy, the whole machine balancing cardio-pulmonary function is fundamentally treated coronary heart disease.
Prove through clinical application for many years, medicine of the present invention is evident in efficacy to cardiovascular stasis coronary heart disease, to other various disease type coronary heart disease, such as cold coagulation heart arteries and veins type coronary heart disease, qi stagnation and blood stasis type coronary heart disease, type of stagnation of turbid phlegm coronary heart disease, coronary artery disease with deficiency of both qi and yin, yang deficiency of spleen and stomache coronary heart disease etc., can be used as the main formula medicine and merge other Chinese medicines with the disease compatibility.State of an illness the lighter took medicine after a week, but the symptom complete obiteration, sick severe one was taken medicine after a week, and symptom can obviously alleviate, and can eliminate symptom after serveing on one or two month.Can keep gentle phychology and living habit preferably after the recovery from illness, can be without the melancholy of recurrence.
The medicine property of medicine of the present invention is gentle, and produce effects is rapid, stable curative effect, and relapse rate is low, and prescription is simplified, safely, have no side effect.
The specific embodiment
Below in conjunction with embodiment and test example the present invention is done a progressive description:
Embodiment 1: the preparation of medicine of the present invention " red lunar caustic ": get 2.5 kilograms of Folium Ginkgos, 2 kilograms of Radix Salviae Miltiorrhizaes, each 1 kilogram in Rhizoma Chuanxiong, Flos Carthami and Radix Notoginseng, after the screening purified treatment, be developed into according to a conventional method fine powder, evenly packing after fully mixing gets " red lunar caustic " that every bag 3 restrains.
Usage and dosage: warm boiled water, three times on the one, each bag, seven days is a course for the treatment of.
Embodiment 2: the preparation of medicine of the present invention " red lunar caustic ": get 2.5 kilograms of Folium Ginkgos, 2 kilograms of Radix Salviae Miltiorrhizaes, each 1.5 kilograms in Rhizoma Chuanxiong, Flos Carthami and Radix Notoginseng, after the screening purified treatment, be developed into according to a conventional method fine powder, evenly packing after fully mixing gets " red lunar caustic " that every bag 3 restrains.
Usage and dosage: warm boiled water, three times on the one, each bag, seven days is a course for the treatment of.
Embodiment 3: the preparation of medicine of the present invention " red lunar caustic ": get 2 kilograms of Folium Ginkgos, 1.5 kilograms of Radix Salviae Miltiorrhizaes, each 1 kilogram in Rhizoma Chuanxiong, Flos Carthami and Radix Notoginseng, after the screening purified treatment, be developed into according to a conventional method fine powder, evenly packing after fully mixing gets " red lunar caustic " that every bag 3.5 restrains.
Usage and dosage: warm boiled water, three times on the one, each bag, seven days is a course for the treatment of.
Embodiment 4: the preparation of medicine of the present invention " red lunar caustic ": get 3 kilograms of Folium Ginkgos, 2.5 kilograms of Radix Salviae Miltiorrhizaes, each 1.5 kilograms in Rhizoma Chuanxiong, Flos Carthami and Radix Notoginseng, after the screening purified treatment, be developed into according to a conventional method fine powder, evenly packing after fully mixing gets " red lunar caustic " that every bag 3.5 restrains.
Usage and dosage: warm boiled water, three times on the one, each bag, seven days is a course for the treatment of.
Embodiment 5: the preparation of medicine of the present invention " red lunar caustic ": get 2.5 kilograms of Folium Ginkgos, 2 kilograms of Radix Salviae Miltiorrhizaes, each 1.2 kilograms in Rhizoma Chuanxiong, Flos Carthami and Radix Notoginseng, after the screening purified treatment, be developed into according to a conventional method fine powder, evenly packing after fully mixing gets " red lunar caustic " that every bag 4 restrains.
Usage and dosage: warm boiled water, three times on the one, each bag, seven days is a course for the treatment of.
Test example: the clinical observation of medicine of the present invention " red lunar caustic " treatment coronary heart disease:
The inventor is from 1997---during 2010, accept patients with coronary heart disease totally 486 examples for medical treatment, male 211 examples wherein, women 275 examples, 53.85 years old mean age.Cardiovascular stasis coronary heart disease 283 examples wherein, other type coronary heart disease 203 examples.
The patient takes embodiment 1 prepared " red lunar caustic ", uses warm boiled water at every turn, and three times on the one, each bag, seven days is a course for the treatment of.
Observe three to five courses for the treatment of, drug withdrawal check later six months, healing there is no recurrence and is produce effects, and sb.'s illness took a favorable turn is evident as effectively, and it is not obvious that sb.'s illness took a favorable turn is invalid.
Therapeutic outcome is as follows:
Coronary disease disease type Cure (produce effects) Effectively Invalid Effective percentage %
Type of obstruction of heart-blood 213 examples 56 examples 14 examples 95
Other type 148 examples 36 examples 19 examples 90
In sum, medicine of the present invention has good curative effect to coronary heart disease, and especially evident in efficacy to cardiovascular stasis coronary heart disease, treated effect reaches 95%.
Show through clinical observation: the medicine property of medicine of the present invention is gentle, and produce effects is rapid, stable curative effect, and relapse rate is low, safely, have no side effect.Can regulate cardiac function, improve myocardium blood oxygen supply situation, potent dredging stagnation of heart-blood is arranged, the beneficial heart is astringed the lung, removing dampness, vessel softening, blood fat reducing, adjusting blood pressure, nourishing blood to tranquillize the mind, activating QI to alleviate the depression, the effects such as blood stasis dispelling analgesic therapy.
Above-mentioned various material medicine all passes through strict correct processing and concocts, wherein Folium Ginkgo must detoxification, the processing that completes, medicine of the present invention has following points for attention in therapeutic process:
1, the careful usefulness of bleeding tendency person is arranged.
2, slight gastrointestinal upset person one after each meal, the careful usefulness of severe responder are arranged.
3, the careful usefulness of anemia of pregnant woman and child.
4, long-term taking needs to withdraw in a week two days more than two months.
The below is model case:
Case 1: wear certain, the women, 63 years old, the coronary heart disease that starts in 1994 slightly had fatigue just to show effect nervous, uncomfortable in chest, and three to five paroxysmal angina pectoriss are arranged per month, and degree is slight, and blood pressure is normal.Sx↑ in 1996, nervous, uncomfortable in chest taking place frequently, degree is violent during angina pectoris attacks, the whole body limitation of activity, rapid breathing, mute.Take nifedipine, the medicines such as sorbitrate, at one's side long standby " SUXIAO JIUXIN WAN ".
Give " red lunar caustic " powder and swallow in October, 1999, and every day three times, after the week of taking medicine, nervous, number of times uncomfortable in chest obviously reduces, and degree also alleviates.The rear only appearance of two weeks of taking medicine is slightly nervous several times, once of short duration angina pectoris.Taking medicine only has that heart area is uncomfortable several times after three weeks.Clothes are cured after two months continuously, so far not recurrence.
Case 2: Tan, the women, 60 years old, serious cardiopathic medical history is arranged, slight dizzy, weak, nervous all the year round, blood pressure 90/60mmHg, pulse 38-50 time/minute, two lower limb have slight edema.Rear because of the fatigue of living, sx↑.
Give " red lunar caustic " powder and swallow in July, 2010, informs without obvious adverse reaction blood pressure 100/90mmHg, pulse 60 times/minutes every day twice behind the first quarter moon of taking medicine.Dizzy, weak phenomenon disappears, and sensation is such as the normal person.Serve on one month subsequently.So far 1 year without the uncomfortable phenomenon of recurrence heart.
Case 3: Lee, the man, 46 years old, hospital diagnosis was: inferior myocardial infarction, left ventricular enlargement.Angina pectoris is arranged, the heart is vexed and the symptom such as dizzy, 2 years medical histories, the lip purple, the tip of the tongue is dark red.At one's side long standby " nitroglycerin, SUXIAO JIUXIN WAN ".
In March, 1997, give " red lunar caustic " powder and swallow, every day three times, and inactive other treatment medicine.Take medicine after a week, the phenomenon that often happens suddenly angina pectoris night and go out profuse sweating disappears.Lip transfers pale red to after two weeks, and angina pectoris attacks crosses twice, and phenomenon uncomfortable in chest is arranged once in a while, serve on medicine after one month, and appetite increases, and angina pectoris, the vexed phenomenon of the heart do not occur, and can carry out slight physical training.Continued subsequently to take medicine two months, conscious normal so far.
Case 4: Lu, the woman, 31 years old, the vexed pain in regio pectoris and left back backache arranged, breathe hard, cardiopalmus, tinnitus, medical history 5 years.Hospital diagnosis is: coronary heart disease, deficiency myocardial blood supply.
Give " red lunar caustic " powder and swallow in May, 1999, every day three times, and enjoin her to increase dietetic regulation, strengthen nutrition.Take medicine after the week, only feel the chest discomfort during morbidity, back is sent out heavily, breathes aggravation when tired.Take medicine after two weeks, the vexed pain in regio pectoris do not occur, the tinnitus number of times reduces, and the sensation breathing is also happy, and it is enough.After serve on medicine two months, do not send out so far the chest discomfort.
Case 5: Liu, man, 36 years old, for a long time uncomfortable in chest, cardiopalmus, paroxysmal angina pectoris, migraine, dizzy, insomnia, medical history 5 years.Hospital diagnosis is: coronary heart disease, hyperlipidemia, skull bottom artery blood vessel blood supply insufficiency.
Give " red lunar caustic " powder and swallow in August, 1997, and every day three times, engagement head acupoint massage can not high fat diet.Take medicine after a week, the angina pectoris that remains dormant, sleep quality improves, had palpitation.Advise it to attempt changing living habit, gentle phychology.Taking medicine, there have once in a while after two weeks to be slightly uncomfortable in chest, dizzy, once slight angina pectoris, secondary insomnia.Take medicine and only feel chest after three weeks discomfort is slightly arranged, angina pectoris do not occur, idol has paroxysmal hemicrania.After serve on medicine two months, do not send out so far the chest discomfort, only sometimes occur dizzy, the insomnia.
Case 6: Huang, woman, 51 years old, uncomfortable in chest, cardiopalmus, angina pectoris, the often angina pectoris that happens suddenly night, medical history 8 years.Hospital diagnosis is: coronary heart disease, acute coronary insufficiency.
Give " red lunar caustic " powder and swallow in June, 2003, every day three times, and after the week of taking medicine, the angina pectoris secondary that happens suddenly night, daytime is sometimes uncomfortable in chest, and medication treatment is not sent out the burst angina pectoris night after two weeks, and once of short duration angina pectoris of outbreak on daytime is slightly uncomfortable in chest.Medication treatment angina pectoris do not occur after three weeks, and chest is slightly uncomfortable.After serve on medicine two months, the angor of not making up one's mind so far.
Case 7: easily certain, the woman, 68 years old, uncomfortable in chest, angina pectoris, hyperlipidemia, blood pressure 140/110mmHg were slow in action, both hands tremble medical history 5 years.Hospital diagnosis is: coronary heart disease, unstable angina pectoris, cerebral thrombosis.
Give " red lunar caustic " powder and swallow in July, 2009, and every day three times, after the week of taking medicine, uncomfortable in chest, angina pectoris degree alleviates number of times and reduces.The second week of taking medicine adds head acupoint massage, massages: push away the maneuvers such as bridge bow, rear heart channel, rear heart cave, 18 turn, medication treatment is after two weeks, and the angor of not making up one's mind has uncomfortable in chest.Medication treatment angina pectoris do not occur, sometimes cardiopalmus after three weeks.After serve on medicine two months, stable disease so far.
Case 8: Lee, man, 31 years old, uncomfortable in chest, angina pectoris, cyanosis, medical history: because of congenital heart disease (ventricular septal defect operative treatment).
Give " red lunar caustic " powder and swallow in June, 2002, takes medicine after the week every day three times, angina pectoris do not occur, take medicine after two weeks, cyanosis obviously alleviates, and slightly uncomfortable in chest, lip is light red, after three weeks of taking medicine, angina pectoris do not occur, cyanosis disappears, after serve on medicine three months, stable disease so far.
Case 9: easily certain, the woman, 67 years old, cardiopalmus, angina pectoris were radiated to back, hyperlipidemia, blood pressure 140/105mmHg, medical history 10 years.Hospital diagnosis is: coronary heart disease, fatigue stable angina pectoris.
In JIUYUE, 2007 gives " red lunar caustic " powder and swallows, every day three times, and after the week of taking medicine, sx↓, cardiopalmus behind the second week of taking medicine, angina pectoris do not appear, sometimes in angina pectoris three times.Take medicine after three weeks, angina pectoris do not occur, slight chest is uncomfortable, after serve on medicine three months, stable disease so far.
Case 10: Lee, the man 47 years old, can have nausea and vomiting when uncomfortable in chest, cardiopalmus, squeezing angina pectoris, morbidity.Medical history 5 years.Hospital diagnosis is: myocardial infarction.
Give " red lunar caustic " powder and swallow February calendar year 2001, four times a day, and after the week of taking medicine, uncomfortable in chest, angina pectoris symptom alleviates.Take medicine after two weeks, the angina pectoris number of times reduces, and is slightly uncomfortable in chest without nausea and vomiting, takes medicine after three weeks, angina pectoris do not occur, and slight chest is uncomfortable, after serve on medicine two months, stable disease so far.

Claims (6)

1. medicine for the treatment of coronary heart disease is characterized in that being made by the crude drug of following weight portion:
20-30 parts of Folium Ginkgos, 15-25 parts of Radix Salviae Miltiorrhizaes, 10-15 parts of Rhizoma Chuanxiongs, 10-15 parts on Flos Carthami, 10-15 parts in Radix Notoginseng.
2. the medicine for the treatment of coronary heart disease according to claim 1 is characterized in that being made by the crude drug of following weight portion:
25 parts of Folium Ginkgos, 20 parts of Radix Salviae Miltiorrhizaes, 10 parts of Rhizoma Chuanxiongs, 10 parts on Flos Carthami, 10 parts in Radix Notoginseng.
3. the medicine for the treatment of coronary heart disease according to claim 1 is characterized in that being made by the crude drug of following weight portion:
25 parts of Folium Ginkgos, 20 parts of Radix Salviae Miltiorrhizaes, 15 parts of Rhizoma Chuanxiongs, 15 parts on Flos Carthami, 15 parts in Radix Notoginseng.
4. the medicine for the treatment of coronary heart disease according to claim 1 is characterized in that being made by the crude drug of following weight portion:
20 parts of Folium Ginkgos, 15 parts of Radix Salviae Miltiorrhizaes, 10 parts of Rhizoma Chuanxiongs, 10 parts on Flos Carthami, 10 parts in Radix Notoginseng.
5. the medicine for the treatment of coronary heart disease according to claim 1 is characterized in that being made by the crude drug of following weight portion:
30 parts of Folium Ginkgos, 25 parts of Radix Salviae Miltiorrhizaes, 15 parts of Rhizoma Chuanxiongs, 15 parts on Flos Carthami, 15 parts in Radix Notoginseng.
6. the medicine for the treatment of coronary heart disease according to claim 1 is characterized in that being made by the crude drug of following weight portion:
25 parts of Folium Ginkgos, 20 parts of Radix Salviae Miltiorrhizaes, 12 parts of Rhizoma Chuanxiongs, 12 parts on Flos Carthami, 12 parts in Radix Notoginseng.
CN 201110273370 2011-09-15 2011-09-15 Medicament for treating coronary heart disease Expired - Fee Related CN102302550B (en)

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Publication number Priority date Publication date Assignee Title
CN103039978A (en) * 2012-12-05 2013-04-17 无锡市天赐康生物科技有限公司 Healthcare food with functions of hypoxia tolerance and immunity improvement and preparation method thereof
CN105031517A (en) * 2015-06-29 2015-11-11 广西健宝石斛有限责任公司 Dendrobium officinale healthcare tea capable of reducing blood fat, blood sugar, and blood pressure and preparation method thereof
CN112451625A (en) * 2020-12-24 2021-03-09 马玉印 Traditional Chinese medicine watered pill for preventing and treating three highs and preparation method thereof

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