CN102272081B - 四氢萘-2-醇衍生物 - Google Patents
四氢萘-2-醇衍生物 Download PDFInfo
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- CN102272081B CN102272081B CN201080004282.2A CN201080004282A CN102272081B CN 102272081 B CN102272081 B CN 102272081B CN 201080004282 A CN201080004282 A CN 201080004282A CN 102272081 B CN102272081 B CN 102272081B
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- compound
- fluorine
- derivatives
- tetrahydronaphthalen
- methyl
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- C07—ORGANIC CHEMISTRY
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- C07C43/00—Ethers; Compounds having groups, groups or groups
- C07C43/02—Ethers
- C07C43/20—Ethers having an ether-oxygen atom bound to a carbon atom of a six-membered aromatic ring
- C07C43/21—Ethers having an ether-oxygen atom bound to a carbon atom of a six-membered aromatic ring containing rings other than six-membered aromatic rings
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- C07C2602/04—One of the condensed rings being a six-membered aromatic ring
- C07C2602/10—One of the condensed rings being a six-membered aromatic ring the other ring being six-membered, e.g. tetraline
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Abstract
Description
Claims (12)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
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EP09155076 | 2009-03-13 | ||
EP09155076.4 | 2009-03-13 | ||
PCT/EP2010/053167 WO2010103095A1 (en) | 2009-03-13 | 2010-03-12 | Tetrahydronaphthalen-2-ol derivatives |
Publications (2)
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CN102272081A CN102272081A (zh) | 2011-12-07 |
CN102272081B true CN102272081B (zh) | 2014-04-30 |
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CN201080004282.2A Expired - Fee Related CN102272081B (zh) | 2009-03-13 | 2010-03-12 | 四氢萘-2-醇衍生物 |
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EP (1) | EP2406206B1 (zh) |
JP (1) | JP5570535B2 (zh) |
KR (1) | KR20110128790A (zh) |
CN (1) | CN102272081B (zh) |
AR (1) | AR075740A1 (zh) |
AU (1) | AU2010223209B2 (zh) |
BR (1) | BRPI1007505A2 (zh) |
CA (1) | CA2748963C (zh) |
ES (1) | ES2404344T3 (zh) |
IL (1) | IL213262A0 (zh) |
MX (1) | MX2011008868A (zh) |
NZ (1) | NZ594085A (zh) |
TW (1) | TW201043595A (zh) |
WO (1) | WO2010103095A1 (zh) |
ZA (1) | ZA201104279B (zh) |
Families Citing this family (1)
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CN110746392B (zh) * | 2019-10-31 | 2023-06-09 | 重庆医科大学 | 一类呋喃化合物在制备抗肿瘤药物中的应用 |
Citations (5)
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CN1305373A (zh) * | 1998-06-16 | 2001-07-25 | 辉瑞产品公司 | 含有选择性***受体调节剂和甲状旁腺激素的治疗组合物 |
WO2001064665A1 (en) * | 2000-03-01 | 2001-09-07 | Akzo Nobel N.V. | Chroman derivatives as estrogenic compounds |
CN1422263A (zh) * | 2000-04-07 | 2003-06-04 | 辉瑞产品公司 | ***激动剂/拮抗剂代谢物 |
WO2006088716A1 (en) * | 2005-02-15 | 2006-08-24 | Eli Lilly And Company | Substituted tetralins as selective estrogen receptor-beta agonists |
CN101092363A (zh) * | 2006-06-23 | 2007-12-26 | 浙江海正天华新药研发有限公司 | 芳基四氢萘类木脂素化合物及其制备方法和用途 |
Family Cites Families (4)
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AT388631B (de) | 1985-04-16 | 1989-08-10 | Siemens Ag Oesterreich | Einrichtung zur steuerung des feldstromes von gleichstrommotoren |
CO5271709A1 (es) * | 2000-01-12 | 2003-04-30 | Pfizer Prod Inc | Composiciones y procedimientos para el y tratamiento de afecciones que responden a estrogenos |
AU781168B2 (en) * | 2001-01-26 | 2005-05-12 | Pfizer Products Inc. | Method of treating certain cancers using an estrogen agonist/antagonist |
CA2467013C (en) | 2001-11-19 | 2010-08-10 | Eli Lilly And Company | Substituted benzopyrans as selective estrogen receptor-beta agonists |
-
2010
- 2010-02-25 TW TW099105514A patent/TW201043595A/zh unknown
- 2010-03-11 AR ARP100100744A patent/AR075740A1/es unknown
- 2010-03-12 CN CN201080004282.2A patent/CN102272081B/zh not_active Expired - Fee Related
- 2010-03-12 NZ NZ594085A patent/NZ594085A/xx not_active IP Right Cessation
- 2010-03-12 MX MX2011008868A patent/MX2011008868A/es not_active Application Discontinuation
- 2010-03-12 CA CA2748963A patent/CA2748963C/en active Active
- 2010-03-12 WO PCT/EP2010/053167 patent/WO2010103095A1/en active Application Filing
- 2010-03-12 BR BRPI1007505A patent/BRPI1007505A2/pt not_active Application Discontinuation
- 2010-03-12 JP JP2011553464A patent/JP5570535B2/ja not_active Expired - Fee Related
- 2010-03-12 EP EP10708535A patent/EP2406206B1/en active Active
- 2010-03-12 AU AU2010223209A patent/AU2010223209B2/en not_active Ceased
- 2010-03-12 KR KR1020117013749A patent/KR20110128790A/ko not_active Application Discontinuation
- 2010-03-12 ES ES10708535T patent/ES2404344T3/es active Active
-
2011
- 2011-05-31 IL IL213262A patent/IL213262A0/en unknown
- 2011-06-08 ZA ZA2011/04279A patent/ZA201104279B/en unknown
Patent Citations (5)
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CN1305373A (zh) * | 1998-06-16 | 2001-07-25 | 辉瑞产品公司 | 含有选择性***受体调节剂和甲状旁腺激素的治疗组合物 |
WO2001064665A1 (en) * | 2000-03-01 | 2001-09-07 | Akzo Nobel N.V. | Chroman derivatives as estrogenic compounds |
CN1422263A (zh) * | 2000-04-07 | 2003-06-04 | 辉瑞产品公司 | ***激动剂/拮抗剂代谢物 |
WO2006088716A1 (en) * | 2005-02-15 | 2006-08-24 | Eli Lilly And Company | Substituted tetralins as selective estrogen receptor-beta agonists |
CN101092363A (zh) * | 2006-06-23 | 2007-12-26 | 浙江海正天华新药研发有限公司 | 芳基四氢萘类木脂素化合物及其制备方法和用途 |
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John W Ullrich等.Estrogen receptor modulator review.《EXPERT OPINION ON THERAPEUTIC PATENTS》.2006,第16卷(第5期), |
Also Published As
Publication number | Publication date |
---|---|
TW201043595A (en) | 2010-12-16 |
MX2011008868A (es) | 2011-09-15 |
CN102272081A (zh) | 2011-12-07 |
KR20110128790A (ko) | 2011-11-30 |
JP2012520265A (ja) | 2012-09-06 |
JP5570535B2 (ja) | 2014-08-13 |
AR075740A1 (es) | 2011-04-20 |
ES2404344T3 (es) | 2013-05-27 |
AU2010223209A1 (en) | 2011-06-30 |
EP2406206A1 (en) | 2012-01-18 |
BRPI1007505A2 (pt) | 2016-02-23 |
CA2748963C (en) | 2017-03-28 |
IL213262A0 (en) | 2011-07-31 |
AU2010223209B2 (en) | 2014-07-24 |
CA2748963A1 (en) | 2010-09-16 |
EP2406206B1 (en) | 2013-01-30 |
ZA201104279B (en) | 2012-02-29 |
WO2010103095A1 (en) | 2010-09-16 |
NZ594085A (en) | 2013-01-25 |
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