CN102246965A - Production method of microcapsule containing vitamin F - Google Patents
Production method of microcapsule containing vitamin F Download PDFInfo
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- CN102246965A CN102246965A CN2011101275949A CN201110127594A CN102246965A CN 102246965 A CN102246965 A CN 102246965A CN 2011101275949 A CN2011101275949 A CN 2011101275949A CN 201110127594 A CN201110127594 A CN 201110127594A CN 102246965 A CN102246965 A CN 102246965A
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Abstract
The invention discloses a production method of a microcapsule containing vitamin F. The vitamin F is also known as a gamma-linolenic acid which is an unsaturated fatty acid and plays an important role in growth of the brain and retina of infants. The production method of the microcapsule containing vitamin F comprises the following four steps of: (1) adding 0.6-9 parts by weight of gelatin and 0.6-9 parts by weight of powdered sugar into water, and stirring at 40-60 DEG C until the mixture is fully dissolved to form a wall material solution of which the concentration is 2-20%; (2) after the temperature of the wall material solution formed in the step (1) decreases to the room temperature, adding 1 part by weight of core material-vitamin F, taking evening primrose oil as a carrier, and stirring to form emulsion; (3) carrying out high-shear emulsification on the emulsion formed in the step (2) to prepare stable O/W type emulsion; and (4) spray-drying the emulsion formed in the step (3) to obtain microcapsule powder containing vitamin F. The production method disclosed by the invention is applied to foods and health care products.
Description
Technical field:
Invention relates to a kind of food and field of health care products of being used for; Being specifically related to a kind of is the production method that carrier contains the vitaminF microcapsules with the evening primrose oil.
Background technology:
VitaminF is gamma-Linolenic acid (γ-linolenic acid) again, is a kind of unrighted acid, and infant's brain, retinal development are played an important role.In a single day human body lacks this unrighted acid, will produce the unusual and disorderly of systems such as immunity, cardiovascular and cerebrovascular, reproduction and secretion.And gamma-Linolenic acid is that the mankind itself can not synthesize or substitutes, and can only absorb from food.VitaminF finds from evening primrose that at first content is 8% ~ 11%, and evening primrose is the wild plant of China the Northeast, and reserves are abundant, and wide material sources are so select the carrier of evening primrose oil as vitaminF.Be rich in multiple unrighted acids such as vitaminF in the evening primrose oil, contain a large amount of height unsaturated double-bonds, very easily oxidation and going bad in air loses pharmacological action originally, and produces harmful toxic matter.
U.S.'s official approval vitaminF is " generally recognized as safe material ".In addition, have in the world more than 30 country with vitaminF as nourishing additive agent or functional food ingredients.So demand and day sharp increase for vitaminF.But the vitaminF product of listing is also considerably less at present, has so just limited the application of vitaminF greatly.Because vitaminF can't be added directly in the middle of the ordinary populace food.
Use gelatin as the wall material separately, the toughness and the compactness extent of softgel shell are bad, break easily, and the evaporation meeting owing to moisture produce small pore on softgel shell in spray-dired process.
Summary of the invention:
The purpose of invention provides a kind of use gelatin-Icing Sugar that passes through as the wall material, under lower temperature the evening primrose oil that contains vitaminF is carried out microencapsulation, and it is easily oxidized to have solved vitaminF, is difficult to carry out with other compositions the problem of compatibility; And microcapsules mobile fine of preparation, can keep the activity of vitaminF preferably.
Above-mentioned purpose realizes by following technical scheme:
A kind of production method that contains the vitaminF microcapsules, described production method comprised for four steps: the first step is that 0.6 ~ 9 gelatin and parts by weight are that 0.6 ~ 9 Icing Sugar adds in the entry with parts by weight, stirs under 40 ~ 60 ℃ of conditions, until dissolving fully, form 2% ~ 20% wall material solution; Second step treated that the wall material solution that forms in the first step reduced to room temperature, added weight portion and was core-vitaminF of 1 and be carrier with the evening primrose oil, stirred the back and formed emulsion; The 3rd step was prepared into stable O/W type emulsion with the emulsion high-shear emulsifying that forms in second step; The 4th step was carried out spray-drying with the emulsion that forms in the 3rd step, promptly got and contained the vitaminF microscapsule powder.
The described production method that contains the vitaminF microcapsules, the described average grain diameter that contains the vitaminF microscapsule powder is 0.1 ~ 25 μ m.
The described production method that contains the vitaminF microcapsules, the described outward appearance that contains the vitaminF microscapsule powder presents sphere, microcapsules smooth outer surface, softgel shell densification.
The described production method that contains the vitaminF microcapsules, the described envelop rate of vitaminF microscapsule powder that contains is greater than 90%.
Beneficial effect:
1. the present invention will contain the evening primrose oil microencapsulation of vitaminF, improve the stability in preservation, processing, the application process.
2. grease of the present invention by microencapsulation after, can reduce grease thermal sensitivity, prevent that the light sensitivity composition is damaged, improved trophism, flavor stability and the bioavilability of oil product.
3. it is easily oxidized to the invention solves vitaminF, is difficult to carry out with other compositions the problem of compatibility; And microcapsules mobile fine of preparation, can keep the activity of vitaminF preferably.
4. the present invention uses Icing Sugar as another kind of wall material, and sucrose is cheap and effect is fine, has reduced production cost.
5. the present invention can prevent the oxidative rancidity of the unrighted acids such as vitaminF in the evening primrose oil effectively, has increased the stability of unrighted acid, keeps its activity, has improved the bioavilability of vitaminF, is convenient to add in food and the health products.
6. the gelatin and the sucrose of the present invention's use are natural food material, safe in utilization, stable in properties, and can make the liquid fat powdered effectively, prevent that grease from contacting with air, slow down the oxidation deterioration of multiple unrighted acids such as vitaminF, can also shelter the bad smell of unrighted acid.
7. production technology of the present invention is simple, cost is low, the vitaminF microcapsule product of producing that contains has good flowability, dispersiveness and palatability, and be difficult for the moisture absorption, can be applicable to food, medicine, health products, cosmetics and food additives, greatly increased the range of application of vitaminF.
Description of drawings:
Accompanying drawing 1 is that this product is the sem photograph that the preparation of wall material contains the vitaminF microcapsules with gelatin-Icing Sugar.
Accompanying drawing 2 is the sem photographs that contain the vitaminF microcapsules with the gelatin for the preparation of wall material.
Accompanying drawing 3 is comparison diagrams of accompanying drawing 1 antioxygenic property.
The specific embodiment:
Embodiment 1:
A kind of production method that contains the vitaminF microcapsules, described production method comprised for four steps: the first step is that 0.6 ~ 9 gelatin and parts by weight are that 0.6 ~ 9 Icing Sugar adds in the entry with parts by weight, stirs under 40 ~ 60 ℃ of conditions, until dissolving fully, form 2% ~ 20% wall material solution; Second step treated that the wall material solution that forms in the first step reduced to room temperature, added weight portion and was core-vitaminF of 1 and be carrier with the evening primrose oil, stirred the back and formed emulsion; The 3rd step was prepared into stable O/W type emulsion with the emulsion high-shear emulsifying that forms in second step; The 4th step was carried out spray-drying with the emulsion that forms in the 3rd step, promptly got and contained the vitaminF microscapsule powder.
Embodiment 2:
The embodiment 1 described production method that contains the vitaminF microcapsules, the described average grain diameter that contains the vitaminF microscapsule powder is 0.1 ~ 25 μ m.
Embodiment 3:
Embodiment 1 or the 2 described production methods that contain the vitaminF microcapsules, the described outward appearance that contains the vitaminF microscapsule powder presents sphere, microcapsules smooth outer surface, softgel shell densification.
The described production method that contains the vitaminF microcapsules, the described envelop rate of vitaminF microscapsule powder that contains is greater than 90%.(▲) is vitaminF in the accompanying drawing 3; () for containing the microcapsules of vitaminF.
Embodiment 4:
The described production method that contains the vitaminF microcapsules of above embodiment takes by weighing the wall material (gelatin: Icing Sugar=3: 7) add in the entry, stir down at 40 ℃ it is dissolved fully, form 5% wall material solution of 0.6 weight portion; Treat that this wall material solution is cooled to room temperature, in this solution, add the vitaminF (evening primrose oil is a carrier) of 1 weight portion then, stir and form colostrum; Again with this colostrum under 10000 rpm, homogeneous 2 min contain the vitaminF microscapsule powder with this milky emulsion by what spray-drying made white at last, EAT is 180 ℃.Measurement result shows, contains vitaminF microcapsules good fluidity, and oxidation resistance is fine.Measuring the average grain diameter that contains vitaminF microcapsules particulate by laser particle analyzer is 10.26 μ m.
Embodiment 5:
The described production method that contains the vitaminF microcapsules of above embodiment takes by weighing the wall material (gelatin: Icing Sugar=1: 1) add in the entry, stir down at 60 ℃ it is dissolved fully, form 10% wall material solution of 1 weight portion; Treat that this wall material solution is cooled to room temperature, in this solution, add the vitaminF (evening primrose oil is a carrier) of 1 weight portion then, stir and form colostrum; Again with this colostrum under 12000 rpm, homogeneous 2 min contain the vitaminF microscapsule powder with this milky emulsion by what spray-drying made white at last, EAT is 170 ℃.Measurement result shows, contains vitaminF microcapsules good fluidity, and oxidation resistance is better.Measuring the average grain diameter that contains vitaminF microcapsules particulate by laser particle analyzer is 12.58 μ m.
Embodiment 6:
The described production method that contains the vitaminF microcapsules of above embodiment takes by weighing the wall material (gelatin: Icing Sugar=3: 2) add in the entry, stir down at 50 ℃ it is dissolved fully, form 15% wall material solution of 3 weight portions; Treat that this wall material solution is cooled to room temperature, in this solution, add the vitaminF (evening primrose oil is a carrier) of 1 weight portion then, stir and form colostrum; Again with this colostrum under 14000 rpm, homogeneous 3 min contain the vitaminF microscapsule powder with this milky emulsion by what spray-drying made white at last, EAT is 200 ℃.Measurement result shows, contains vitaminF microcapsules good fluidity, and oxidation resistance is fine.Measuring the average grain diameter that contains vitaminF microcapsules particulate by laser particle analyzer is 9.98 μ m.
Embodiment 7:
The described production method that contains the vitaminF microcapsules of above embodiment takes by weighing the wall material (gelatin: Icing Sugar=7: 3) add in the entry, stir down at 40 ℃ it is dissolved fully, form 20% wall material solution of 5 weight portions; Treat that this wall material solution is cooled to room temperature, in this solution, add the vitaminF (evening primrose oil is a carrier) of 1 weight portion then, stir and form colostrum; Again with this colostrum under 15000 rpm, homogeneous 5 min contain the vitaminF microscapsule powder with this milky emulsion by what spray-drying made white at last, EAT is 180 ℃.Measurement result shows, contains vitaminF microcapsules good fluidity, and oxidation resistance is better.Measuring the average grain diameter that contains vitaminF microcapsules particulate by laser particle analyzer is 15.46 μ m.
Embodiment 8:
The described production method that contains the vitaminF microcapsules of above embodiment takes by weighing the wall material (gelatin: Icing Sugar=2: 3) add in the entry, stir down at 50 ℃ it is dissolved fully, form 5% wall material solution of 7 weight portions; Treat that this wall material solution is cooled to room temperature, in this solution, add the vitaminF (evening primrose oil is a carrier) of 1 weight portion then, stir and form colostrum; Again with this colostrum under 10000 rpm, homogeneous 1 min contains the vitaminF microscapsule powder with this milky emulsion by what spray-drying made white at last, EAT is 180 ℃.Measurement result shows, contains vitaminF microcapsules good fluidity, and oxidation resistance is good.Measuring the average grain diameter that contains vitaminF microcapsules particulate by laser particle analyzer is 16.46 μ m.
Embodiment 9:
The described production method that contains the vitaminF microcapsules of above embodiment takes by weighing the wall material (gelatin: Icing Sugar=11: 9) add in the entry, stir down at 45 ℃ it is dissolved fully, form 10% wall material solution of 9 weight portions; Treat that this wall material solution is cooled to room temperature, in this solution, add the vitaminF (evening primrose oil is a carrier) of 1 weight portion then, stir and form colostrum; Again with this colostrum under 18000 rpm, homogeneous 2 min contain the vitaminF microscapsule powder with this milky emulsion by what spray-drying made white at last, EAT is 190 ℃.Measurement result shows, contains vitaminF microcapsules good fluidity, and oxidation resistance is better.Measuring the average grain diameter that contains vitaminF microcapsules particulate by laser particle analyzer is 13.87 μ m.
Embodiment 10:
The described production method that contains the vitaminF microcapsules of above embodiment takes by weighing the wall material (gelatin: Icing Sugar=7: 13) add in the entry, stir down at 45 ℃ it is dissolved fully, form 6% wall material solution of 2 weight portions; Treat that this wall material solution is cooled to room temperature, in this solution, add the vitaminF (evening primrose oil is a carrier) of 1 weight portion then, stir and form colostrum; Again with this colostrum under 12000 rpm, homogeneous 5 min contain the vitaminF microscapsule powder with this milky emulsion by what spray-drying made white at last, EAT is 180 ℃.Measurement result shows, contains vitaminF microcapsules good fluidity, and oxidation resistance is very good.Measuring the average grain diameter that contains vitaminF microcapsules particulate by laser particle analyzer is 9.76 μ m.
Claims (5)
1. production method that contains the vitaminF microcapsules, it is characterized in that: described production method comprised for four steps: the first step, with parts by weight is that 0.6 ~ 9 gelatin and parts by weight are that 0.6 ~ 9 Icing Sugar adds in the entry, under 40 ~ 60 ℃ of conditions, stir, until dissolving fully, form 2% ~ 20% wall material solution; Second step treated that the wall material solution that forms in the first step reduced to room temperature, added weight portion and was core-vitaminF of 1 and be carrier with the evening primrose oil, stirred the back and formed emulsion; The 3rd step was prepared into stable O/W type emulsion with the emulsion high-shear emulsifying that forms in second step; The 4th step was carried out spray-drying with the emulsion that forms in the 3rd step, promptly got and contained the vitaminF microscapsule powder.
2. the production method that contains the vitaminF microcapsules according to claim 1 is characterized in that: the described average grain diameter that contains the vitaminF microscapsule powder is 0.1 ~ 25 μ m.
3. the production method that contains the vitaminF microcapsules according to claim 1 and 2 is characterized in that: the described outward appearance that contains the vitaminF microscapsule powder presents sphere, microcapsules smooth outer surface, softgel shell densification.
4. the production method that contains the vitaminF microcapsules according to claim 1 and 2 is characterized in that: the described envelop rate of vitaminF microscapsule powder that contains is greater than 90%.
5. the production method that contains the vitaminF microcapsules according to claim 3 is characterized in that: the described envelop rate of vitaminF microscapsule powder that contains is greater than 90%.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201110127594.9A CN102246965B (en) | 2011-05-17 | 2011-05-17 | Production method of microcapsule containing vitamin F |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201110127594.9A CN102246965B (en) | 2011-05-17 | 2011-05-17 | Production method of microcapsule containing vitamin F |
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| Publication Number | Publication Date |
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| CN102246965A true CN102246965A (en) | 2011-11-23 |
| CN102246965B CN102246965B (en) | 2015-01-28 |
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| Application Number | Title | Priority Date | Filing Date |
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| CN201110127594.9A Expired - Fee Related CN102246965B (en) | 2011-05-17 | 2011-05-17 | Production method of microcapsule containing vitamin F |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106821998A (en) * | 2017-03-28 | 2017-06-13 | 深圳万和制药有限公司 | Prepare the method and its compound amino acid capsule composition of vitaminAD micropill |
-
2011
- 2011-05-17 CN CN201110127594.9A patent/CN102246965B/en not_active Expired - Fee Related
Non-Patent Citations (2)
| Title |
|---|
| 左爱仁 等: "番茄红素微胶囊化的研究", 《食品科学》 * |
| 徐丽琴 等: "月见草油微胶囊技术的研究", 《辽宁师范大学学报（自然科学版）》 * |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106821998A (en) * | 2017-03-28 | 2017-06-13 | 深圳万和制药有限公司 | Prepare the method and its compound amino acid capsule composition of vitaminAD micropill |
| CN106821998B (en) * | 2017-03-28 | 2020-03-10 | 深圳万和制药有限公司 | Method for preparing vitamin AD micro-pills and compound amino acid capsule composition thereof |
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| Publication number | Publication date |
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| CN102246965B (en) | 2015-01-28 |
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