CN102228554A - Medicament for treating empyrosis and scalding and preparation method thereof - Google Patents

Medicament for treating empyrosis and scalding and preparation method thereof Download PDF

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Publication number
CN102228554A
CN102228554A CN2011101839227A CN201110183922A CN102228554A CN 102228554 A CN102228554 A CN 102228554A CN 2011101839227 A CN2011101839227 A CN 2011101839227A CN 201110183922 A CN201110183922 A CN 201110183922A CN 102228554 A CN102228554 A CN 102228554A
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percent
medicament
cera flava
medicine
heating
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CN2011101839227A
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CN102228554B (en
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李亚
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Abstract

The invention relates to a medicament for treating empyrosis and scalding and a preparation method thereof. The medicament of a formula comprises the following components in percentage by weight: 25 to 40 percent of bee glue, 2 to 5 percent of golden thread, 1 to 3 percent of phellodendron, 1 to 3 percent of pangolin scales, 1 to 2 percent of borneol, 30 to 55 percent of colza oil and 15 to 32 percent of sesame oil. The preparation method comprises the following steps of: grinding the golden thread, the phellodendron, the pangolin scales and the borneol into 80 to 100-mesh powder for later use; putting the colza oil and the sesame oil into a container, and heating to the temperature of between 180 and 240 DEG C; adding the bee glue, and after the bee glue is dissolved completely, cooling naturally to the temperature of between 60 and 80 DEG C; and adding the powdery medicaments ground in advance, heating, stirring and decocting at the heating temperature of between 60 and 80 DEG C for 200 to 240 minutes, and concentrating to form paste. The medicament can produce an effect quickly in inflammation diminishing and detumescence and has an obvious effect of easing pain, and a physiological structure of skin hair follicles can be reconstructed. By the preparation method, active ingredients of each medicament can be kept effectively, so that the prepared medicament is high in curative effect.

Description

A kind of medicine for the treatment of empyrosis and preparation method thereof
Technical field
The technical field of pharmaceuticals that the invention belongs to the treatment burn and scald.
Background technology
Existing treatment burn and the medicine of scalding, have that medical expense is high, patient's pain obviously, many, the anti-inflammation detumescence of injury transudate slowly, can't rebuild the skin follicle physiological structure, treatment time is grown even need the surgery cost of great number to carry out characteristics such as skin grafting, and leave a large amount of cicatrixes after healing usually, patient's appearance changes bigger, the limb function serious degradation, be subjected to society, family's grievous discrimination, mental pressure is huge.
Summary of the invention
Purpose of the present invention provides a kind of anti-inflammation detumescence instant effect just for the weak point that overcomes the existing medicine for the treatment of burn and scalding, analgesic effect is remarkable and can rebuild the treatment burn of skin follicle physiological structure and the cream drug of scald, and the present invention also provides the preparation method of this medicine.
The objective of the invention is to realize by following technical solution.
A kind of medicine for the treatment of empyrosis, the weight ratio of this pharmaceutical formulation is: Cera Flava 25%-40%, Rhizoma Coptidis 2%-5%, Cortex Phellodendri 1%-3%, Squama Manis 1%-3%, Borneolum Syntheticum 1%-2%, Oleum Brassicae campestris 30%-55%, Oleum sesami 15%-32%.
A kind of preparation method for the treatment of the medicine of empyrosis, be milled into behind the 80-100 purpose powdery Rhizoma Coptidis, Cortex Phellodendri, Squama Manis, Borneolum Syntheticum standby, earlier Oleum Brassicae campestris and Oleum sesami are put into container internal heating to 180 ℃-240 ℃ of degree, put into Cera Flava then, treat that Cera Flava dissolves fully after, naturally cool to 60 ℃ of-80 ℃ of degree again, add the medicine that grinds to form powdery in advance then, reheat is under the heating-up temperature condition of keeping 60 ℃ of-80 ℃ of degree, stirred through 200-240 minute and to boil, be condensed into behind the paste.Advance the remarkable efficacy of skin follicle functional rehabilitation.Damage the property injury owing to the cause of disease of burn and scald mostly is skin, the muscle that the reason of physics or chemistry causes, medicine of the present invention is used for the treatment of burn and scald and has significant curative effect.Have the treatment II ° with interior burn, skin healing is good, preventing from scar; III is ° with interior burn, and cicatrix is light, does not influence limb function, and can rebuild the advantages such as physiological structure of skin, hair follicle. and on Chinese medicine and pharmacy, Cera Flava just has the effect of detoxifcation, granulation promoting, analgesic therapy from ancient times.Through the discovering of western medicine in modern age, effect such as Cera Flava has that antiinflammatory is antibacterial, local anesthesia, blood fat reducing and prevention of arterial are atherosis.When being applied to burn wound's treatment, Cera Flava is the base substance that forms framework.Cera Flava is to be secreted out by the abdominal part of Apis, is the material of Apis nesting, and main component is the palmitic acid cerolein, molecular formula is C15H31COOC30H61, and fusing point is 62~67 ℃, can increase the denseness of ointment, and more weak water absorption is arranged, and the suction back forms thick water-in-oil type (W/O) Emulsion.Because the Cera Flava molecular weight is bigger, fusing point is higher, and easily forms network, so played the effect of framework, each space during this framework cuts off is 19~25 millimicrons.The oil droplet that contains the mass efficient composition can freely pass through in framework, is easily absorbed by wound surface, degrades, and comprising: hydrolysis, enzymolysis, become sour and saponification.Cera Flava has then been stayed the outside of wound surface, and framework and water miscible material have formed white protecting film.Rhizoma Coptidis bitter in the mouth cold in nature has heat clearing and damp drying, the effect of eliminating fire and detoxication.The Cortex Phellodendri heat clearing and damp drying, eliminating fire and detoxication, clearind deficient heat can be used for pathopyretic ulcer, diseases such as eczema.Squama Manis has the eliminating carbuncle evacuation of pus, external hemostatic effect.Borneolum Syntheticum has antiinflammatory, antibiotic, the effect of clearing away heat to alleviate pain.Oleum sesami has moist, the effect of removing the necrotic tissue and promoting granulation.
Medicine of the present invention has that detoxicating is analgesic, antibiotic, the pain relieving of sterilization, change corruption, granulation promoting, short with interior burn, and cicatrix is light, does not influence limb function, and can rebuild the physiological structure of skin follicle.
Process for preparing medicine of the present invention can effectively keep the effective ingredient of each medicine, makes the curative effect of medication for preparing best.And preparation method is simple.
Aspect treatment time, for I ° burn and scald, the drug of topical application obviously took effect later in 1 hour, showed as that pain disappears, redness obviously alleviates, and cured in 3-5 days.For II ° burn and scald, the drug of topical application obviously took effect later in 3 days, showed as 1 hour later pain relief of the drug of topical application, and 3 days later rednesses of the drug of topical application alleviate, and cure in 7-20 days.For depth-III ° burn and scald, the drug of topical application obviously took effect later in 7 days, show as the drug of topical application 1 day after pain obviously alleviate, redness obviously alleviates after 7 days, the wound sepage obviously reduces in the drug of topical application, cures in 50-70 days.
This product external is applicable to various burns, scald, innominate toxic swelling, external hemorrhoid etc.
Cream drug of the present invention uses through the surgery and the 20000 many cases patients among the people of how tame medical institutions, and to burn, scald, innominate toxic swelling, external hemorrhoid etc., the external application affected part had significant curative effect after 1-24 hours; According to course of therapy, total effective rate reaches more than 98%.
Further set forth content of the present invention below in conjunction with embodiment.
The specific embodiment
Embodiment one
The weight ratio of pharmaceutical formulation is: Cera Flava 25%, Rhizoma Coptidis 3%, Cortex Phellodendri 3%, Squama Manis 3%, Borneolum Syntheticum 1%, Oleum Brassicae campestris 45%, Oleum sesami 20%.Be milled into behind the 80 purpose powderies Rhizoma Coptidis, Cortex Phellodendri, Squama Manis, Borneolum Syntheticum standby, earlier Oleum Brassicae campestris and Oleum sesami are put into container internal heating to 180 ℃-200 ℃ of degree, put into Cera Flava then, after treating that Cera Flava dissolves fully, naturally cool to 60 ℃ of-80 ℃ of degree again, add the medicine that grinds to form powdery in advance then, reheat, under the heating-up temperature condition of keeping 60 ℃ of-80 ℃ of degree, after boiling, be condensed into paste, stirring in 200 minutes promptly obtains medicine of the present invention.
Embodiment two
The weight ratio of pharmaceutical formulation is: Cera Flava 29%, Rhizoma Coptidis 5%, Cortex Phellodendri 1%, Squama Manis 1%, Borneolum Syntheticum 2%, Oleum Brassicae campestris 30%, Oleum sesami 32%.Be milled into behind the 100 purpose powderies Rhizoma Coptidis, Cortex Phellodendri, Squama Manis, Borneolum Syntheticum standby, earlier Oleum Brassicae campestris and Oleum sesami are put into container internal heating to 200 ℃-220 ℃ of degree, put into Cera Flava then, after treating that Cera Flava dissolves fully, naturally cool to 60 ℃ of-80 ℃ of degree again, add the medicine that grinds to form powdery in advance then, reheat, under the heating-up temperature condition of keeping 60 ℃ of-80 ℃ of degree, stirred through 220 minutes and to boil, be condensed into behind the paste cream drug.
Embodiment three
The weight ratio of pharmaceutical formulation is: Cera Flava 40%, Rhizoma Coptidis 2%, Cortex Phellodendri 2%, Squama Manis 2%, Borneolum Syntheticum 2%, Oleum Brassicae campestris 37%, Oleum sesami 15%.Be milled into behind the 80 purpose powderies Rhizoma Coptidis, Cortex Phellodendri, Squama Manis, Borneolum Syntheticum standby, earlier Oleum Brassicae campestris and Oleum sesami are put into container internal heating to 220 ℃-240 ℃ of degree, put into Cera Flava then, after treating that Cera Flava dissolves fully, naturally cool to 60 ℃ of-70 ℃ of degree again, add the medicine that grinds to form powdery in advance then, reheat, under the heating-up temperature condition of keeping 60 ℃ of-70 ℃ of degree, stirred through 240 minutes and to boil, be condensed into behind the paste cream drug.
Embodiment four
The weight ratio of pharmaceutical formulation is: Cera Flava 25%, Rhizoma Coptidis 2%, Cortex Phellodendri 1%, Squama Manis 1%, Borneolum Syntheticum 1%, Oleum Brassicae campestris 55%, Oleum sesami 15%.Be milled into behind the 80-90 purpose powdery Rhizoma Coptidis, Cortex Phellodendri, Squama Manis, Borneolum Syntheticum standby, earlier Oleum Brassicae campestris and Oleum sesami are put into container internal heating to 200 ℃-240 ℃ of degree, put into Cera Flava then, after treating that Cera Flava dissolves fully, naturally cool to 70 ℃ of-80 ℃ of degree again, add the medicine that grinds to form powdery in advance then, reheat, under the heating-up temperature condition of keeping 70 ℃ of-80 ℃ of degree, stirred through 200-220 minute and to boil, be condensed into behind the paste cream drug.
Embodiment five
The weight ratio of pharmaceutical formulation is: Cera Flava 40%, Rhizoma Coptidis 2%, Cortex Phellodendri 2%, Squama Manis 2%, Borneolum Syntheticum 2%, Oleum Brassicae campestris 37%, Oleum sesami 15%.Be milled into behind the 90-100 purpose powdery Rhizoma Coptidis, Cortex Phellodendri, Squama Manis, Borneolum Syntheticum standby, earlier Oleum Brassicae campestris and Oleum sesami are put into container internal heating to 180 ℃-240 ℃ of degree, put into Cera Flava then, after treating that Cera Flava dissolves fully, naturally cool to 60 ℃ of-80 ℃ of degree again, add the medicine that grinds to form powdery in advance then, reheat, under the heating-up temperature condition of keeping 60 ℃ of-80 ℃ of degree, stirred through 220-240 minute and to boil, be condensed into behind the paste cream drug.
Embodiment six
The weight ratio of pharmaceutical formulation is: Cera Flava 50g, Rhizoma Coptidis 8g, Cortex Phellodendri 2g, Squama Manis 6g, Borneolum Syntheticum 2g, Oleum Brassicae campestris 68g, Oleum sesami 64g.Be milled into behind the 90 purpose powderies Rhizoma Coptidis, Cortex Phellodendri, Squama Manis, Borneolum Syntheticum standby, earlier Oleum Brassicae campestris and Oleum sesami are put into container internal heating to 210 ℃-230 ℃ of degree, put into Cera Flava then, after treating that Cera Flava dissolves fully, naturally cool to 60 ℃ of-80 ℃ of degree again, add the medicine that grinds to form powdery in advance then, reheat, under the heating-up temperature condition of keeping 60 ℃ of-80 ℃ of degree, stirred through 220-230 minute and to boil, be condensed into behind the paste cream drug.
Embodiment seven
The weight ratio of pharmaceutical formulation is: Cera Flava 120g, Rhizoma Coptidis 6g, Cortex Phellodendri 6g, Squama Manis 3g, Borneolum Syntheticum 6g, Oleum Brassicae campestris 90g, Oleum sesami 69g.Be milled into behind the 90-100 purpose powdery Rhizoma Coptidis, Cortex Phellodendri, Squama Manis, Borneolum Syntheticum standby, earlier Oleum Brassicae campestris and Oleum sesami are put into container internal heating to 220 ℃-240 ℃ of degree, put into Cera Flava then, after treating that Cera Flava dissolves fully, naturally cool to 60 ℃ of-70 ℃ of degree again, add the medicine that grinds to form powdery in advance then, reheat, under the heating-up temperature condition of keeping 60 ℃ of-70 ℃ of degree, stirred through 230-240 minute and to boil, be condensed into behind the paste cream drug.
Embodiment eight
The weight ratio of pharmaceutical formulation is: Cera Flava 70g, Rhizoma Coptidis 10g, Cortex Phellodendri 6g, Squama Manis 4g, Borneolum Syntheticum 3g, Oleum Brassicae campestris 77g, Oleum sesami 30g.Be milled into behind the 80-100 purpose powdery Rhizoma Coptidis, Cortex Phellodendri, Squama Manis, Borneolum Syntheticum standby, earlier Oleum Brassicae campestris and Oleum sesami are put into container internal heating to 200 ℃-220 ℃ of degree, put into Cera Flava then, after treating that Cera Flava dissolves fully, naturally cool to 70 ℃ of-80 ℃ of degree again, add the medicine that grinds to form powdery in advance then, reheat, under the heating-up temperature condition of keeping 70 ℃ of-80 ℃ of degree, stirred through 200-220 minute and to boil, be condensed into behind the paste cream drug.
Embodiment nine
The weight ratio of pharmaceutical formulation is: Cera Flava 75g, Rhizoma Coptidis 6g, Cortex Phellodendri 3g, Squama Manis 3g, Borneolum Syntheticum 3g, Oleum Brassicae campestris 165g, Oleum sesami 45g.Be milled into behind the 80-100 purpose powdery Rhizoma Coptidis, Cortex Phellodendri, Squama Manis, Borneolum Syntheticum standby, earlier Oleum Brassicae campestris and Oleum sesami are put into container internal heating to 200 ℃-240 ℃ of degree, put into Cera Flava then, after treating that Cera Flava dissolves fully, naturally cool to 60 ℃ of-80 ℃ of degree again, add the medicine that grinds to form powdery in advance then, reheat, under the heating-up temperature condition of keeping 60 ℃ of-80 ℃ of degree, stirred through 200-240 minute and to boil, be condensed into behind the paste cream drug.

Claims (2)

1. a medicine for the treatment of empyrosis is characterized in that, the weight ratio of this pharmaceutical formulation is: Cera Flava 25%-40%, Rhizoma Coptidis 2%-5%, Cortex Phellodendri 1%-3%, Squama Manis 1%-3%, Borneolum Syntheticum 1%-2%, Oleum Brassicae campestris 30%-55%, Oleum sesami 15%-32%.
2. a kind of preparation method for the treatment of the medicine of empyrosis as claimed in claim 1, it is characterized in that, be milled into behind the 80-100 purpose powdery Rhizoma Coptidis, Cortex Phellodendri, Squama Manis, Borneolum Syntheticum standby, earlier Oleum Brassicae campestris and Oleum sesami are put into container internal heating to 180 ℃-240 ℃ of degree, put into Cera Flava then, after treating that Cera Flava dissolves fully, naturally cool to 60 ℃ of-80 ℃ of degree again, add the medicine that grinds to form powdery in advance then, reheat, under the heating-up temperature condition of keeping 60 ℃ of-80 ℃ of degree, stirred through 200-240 minute and to boil, be condensed into behind the paste.
CN2011101839227A 2011-07-02 2011-07-02 Medicament for treating empyrosis and scalding and preparation method thereof Expired - Fee Related CN102228554B (en)

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Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102526438A (en) * 2012-02-24 2012-07-04 阳俊才 Drug for treating burn and scald and preparation method of same
CN104257718A (en) * 2014-10-13 2015-01-07 王亚斌 Medicine for treating burns
CN112807354A (en) * 2021-04-09 2021-05-18 陈国平 Scald and burn ointment and preparation method thereof
CN114010738A (en) * 2021-12-07 2022-02-08 崔献德 Skin disease treatment formula

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1096203A (en) * 1993-06-10 1994-12-14 王大刚 Chinese medicine burn cream and method for making thereof

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1096203A (en) * 1993-06-10 1994-12-14 王大刚 Chinese medicine burn cream and method for making thereof

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102526438A (en) * 2012-02-24 2012-07-04 阳俊才 Drug for treating burn and scald and preparation method of same
CN102526438B (en) * 2012-02-24 2013-10-30 阳俊才 Drug for treating burn and scald and preparation method of same
CN104257718A (en) * 2014-10-13 2015-01-07 王亚斌 Medicine for treating burns
CN112807354A (en) * 2021-04-09 2021-05-18 陈国平 Scald and burn ointment and preparation method thereof
CN114010738A (en) * 2021-12-07 2022-02-08 崔献德 Skin disease treatment formula

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