CN102228504A - Formula of anticancer Chinese medicine and process for preparing products of anticancer Chinese medicine - Google Patents
Formula of anticancer Chinese medicine and process for preparing products of anticancer Chinese medicine Download PDFInfo
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Abstract
The invention discloses a formula of an anticancer Chinese medicine and a process for preparing products of the anticancer Chinese medicine. The process comprises the following steps of: decocting centipede, eupolyphaga, wall lizard, scorpio, leech, gadfly, toad skin, American ginseng, notoginseng root, ligusticum wallichii, Chinese honeylocust spine and angelica dahurica, filtering, adding Zygosaccharomyces bailii into obtained filtrate and decoction dregs, and statically culturing for 192 to 240 hours at corresponding temperature and humidity to obtain oral liquid, oral tablets or capsules of the anticancer Chinese medicine. The products are used for treating gastric cancer, liver cancer, esophagus cancer, intestinal cancer, lung cancer and other cancers, are directly and orally taken, have quick response and high therapeutic effect and sweet taste, and can be quickly adsorbed, the cancer is not relapsed, and a user does not have sequela or complications after taking the anticancer Chinese medicine; two special processes, namely solid and liquid fermentation processes are realized by applying microorganisms to the Chinese medicine, so that the toxic or side effect of a raw medicine is eliminated, the products are convenient to store and take, and waste decoction dregs are not produced; and the source of raw materials is rich, the medicine is easy to prepare, the cost is low, and the products can be used for both treatment and health protection.
Description
Technical field
The present invention relates to the Chinese medicine technical field, relate in particular to a kind of Chinese medicine medicine for preventing prescription and products thereof preparation technology.
Background technology
Cancer (cancer), medical terminology also claim malignant tumor (malignant neoplasm), claim rock in the Chinese medicine, the not normal and disease that causes of the control growth and proliferation of cell mechanism of serving as reasons.Cancerous cell except grow out of control, normal structure even transfer to other parts of health arround also can local invading via body-internal-circulation system or lymphsystem.The characteristics of cancerous cell are: unrestrictedly, hypertrophy without end, the intravital nutrient substance of patient is consumed in a large number; Cancerous cell discharges multiple toxin, makes human body produce a series of symptoms; Cancerous cell also can be transferred to whole body growth and breeding everywhere, causes that human body is become thin, unable, anemia, inappetence, heating and serious organ function be impaired or the like.
Cancer belongs in Chinese medicine: the category of " cards " such as " lump in the abdomen ", " gathering ", " dysphagic ", and Huatuo points out in " Huatuo's Zhongzang classic ": " the swollen institute of husband's carbuncle skin ulcer does also, and all the vital organs of the human body hold poison and do not flow then life, not merely are jammed the person of sending out also because of Rong Wei "; The Zhang Zhongjing of the Eastern Han Dynasty to the difference of the clinical manifestation of tumor and non-tumor and prognosis further developed Difficult Classic argumentation " long-pending person, disease of ZANG-organs is not moved eventually yet; Poly-person, disease of FU-organ also, disease appearing at regular intervals, migration of pain is for controlling " ...; The Sui Dynasty Chao Yuanfang (550-630 A.D.) is shown " General Treatise on the Cause and Symptoms of Diseases " and has not only been put down in writing many tumor diseases and symptom categorizedly, as diseases such as " lump in the abdomen ", " gathering ", " food is choked ", " regurgitation ", " goiters ", and has discussed the cause of disease, pathogenesis.
Chinese and western medicine respectively has superiority aspect treatment of cancer, and the advantage of western medical treatment is instant effect, but normal because of over-treatment causes the adverse consequences that things turn out contrary to one's wishes, and the side effect severe patient can cause single system or multisystem nonfunction; Advantages of TCM is that the effect of relief of symptoms is obvious, and iatrogenic infringement has good auxiliary treatment effect to the secondary in the middle of the tumor chemoradiotherapy, can treat at cause of disease.Because Chinese medicine ingredients can not well be absorbed by human body in traditional traditional Chinese medical science, curative effect is slow, part Chinese medicine toxic side effect taste bitterness in addition, cause Chinese medicine in treatment, only to play assosting effect, existing treatment of cancer majority is taked the therapy of combining Chinese and Western medicine mode, with operation, the chemicotherapy of doctor trained in Western medicine, in conjunction with Chinese medicine attenuation synergistic, strengthening the body resistance, minimizing misery.
Development along with modern biomedical, the Chinese medicine fermentation technique in quiet thousand is proposed once more, the Chinese medicine fermentation has overcome the defective of Chinese medicine, making Chinese medicine have the advantages such as utilization, curative effect is fast, drug effect is high, have no side effect, the Chinese medicine taste is adjustable that can be absorbed by the body fully, is the revolution to the Chinese medicine industry; Present stage is applied to microorganism Chinese medicine fermentation technique in the treatment of cancer, produce have absorb fast, curative effect is high, instant effect, nothing repeatedly, cheap, taste is sweet, be convenient to deposit, instant and the Chinese medicine finished product of taking back no sequel or complication are not seen as yet.
Summary of the invention
For addressing the above problem, eliminate or alleviate the patient suffering, promote the well-being of mankind, the present inventor concentrates on studies by many decades, characteristic at cancer, Chinese medicine preparation of the present invention and the unique Chinese medicine fermentation technology of combination have been proposed, a kind of Chinese medicine medicine for preventing prescription and products thereof preparation technology is provided, Chinese medicine finished product by this technical recipe preparation have absorb fast, curative effect is high, instant effect, nothing repeatedly, cheap, characteristics such as taste is sweet, be convenient to deposit, instant, and take back no sequel or complication.
The technical solution adopted in the present invention is:
Chinese medicine preparation of the present invention is made (consumption is a weight portion) by following component
Scolopendra 500～550, eupolyphaga 500～550, Gekko Swinhonis 500～550, Scorpio 500～550, Hirudo 500～550, awns worm 500～550, Cutis Bufonis 500～550, Radix Panacis Quinquefolii 900～1000, Radix Notoginseng 900～1000, Rhizoma Chuanxiong 900～1000, Spina Gleditsiae 900～1000, the Radix Angelicae Dahuricae 900～1000.
The preparation method of said components being made product of the present invention is:
(1) with the screening of above-mentioned Chinese medicinal components process, uses Scorpio or herb, remove impurity, add water and be warming up to 100 ℃, decocted 30～50 minutes;
(2) Chinese medicinal components after will decocting is cooled to 25～30 ℃, filters to obtain filtrate and medicinal residues;
(3) in last step gained filtrate, add white sugar, add white sugar and filtrate weight ratio be 1: 10～1: 12, this liquid is sent into culture medium, add Zygosaccharomyces bailii, 30～35 ℃ of design temperatures, humidity is controlled at 25%～30%, and static cultivation 192～240 hours obtains oral liquid of the present invention;
(4) second step was filtered the gained medicinal residues and add white sugar water, described white sugar water is that white sugar is melted in the mixed liquor that forms in the water fully, and the weight ratio before wherein white sugar mixes with water is 1: 10, and the above-mentioned white sugar water of injection immerses to medicinal residues and wherein gets final product in medicinal residues;
(5) the 4th step gained mixture is put into culture medium, add Zygosaccharomyces bailii, 28～35 ℃ of design temperatures, humidity is controlled at 25%～30%, and static cultivation 216～240 hours is taken out the mixture after the fermentation air-dry, smash, obtain solid particle, can be directly oral, also can be used for making oral tablets or capsule.
Chinese medicinal components of the present invention
Scolopendra: endogenous wind stopping spasmolytic, dispersing pathogen accumulation, removing obstruction in the collateral to relieve pain, antitumor, promotion immunologic function; Eupolyphaga: salty in the mouth, cold, poisonous, but removing blood stasis, removing mass, collateral dredging, reason are hindered anticoagulation, anti-hypoxia; Gekko Swinhonis: distinguish the flavor of, cold in nature, slightly poisonous, dispelling wind and relieving convulsion, removing obstruction for relieving pain; Scorpio: the phoenix of dispelling, detoxifcation, pain relieving, collateral dredging; Hirudo: removing blood stasis, removing blood stasis, stimulate the menstrual flow, blood flow increasing promotes the absorption of cephalophyma and ecchymosis, alleviates inflammatory reaction on every side and edema, improves regional flow's circulation; Awns worm: removing blood stasis, detumescence blood stasis dispelling; Cutis Bufonis: heat-clearing and toxic substances removing, diuretic relieving distension, pain relieving calmness; Rhizoma Chuanxiong: the hot temperature of loosing is logical, blood circulation promoting and blood stasis dispelling; Radix Notoginseng: dissipating blood stasis hemostasis, subduing swelling and relieving pain; Radix Panacis Quinquefolii: YIN nourishing and QI supplementing, the mind calming and mentality promoting, clearing away heat and promoting production of body fluid, pathogenic fire reducing are relieved summer heat, and the anticancer growth increases immunologic function; Spina Gleditsiae: draw out pus by applying a plaster to the affected part dispel the wind, detumescence and apocenosis; The Radix Angelicae Dahuricae: dispel the wind dampness, detumescence, pain relieving.
Beneficial effect of the present invention is:
(1) product of the present invention is used for gastric cancer, hepatocarcinoma, esophageal carcinoma, intestinal cancer, pulmonary carcinoma and other cancers, and the oral liquid of production is taken at different patients with tablet, and it is fast to respond well to treatment, and does not have repeatedly;
(2) the present invention is applied in by microorganism and realizes solid and two kinds of special process of liquid fermentation on the Chinese medicine, not only remove the toxic and side effects of former medicine, and product is convenient to deposit, instant, does not produce discarded medicinal residues simultaneously, and raw material of Chinese medicine is fully used;
(3) the raw material of Chinese medicine source is abundant, and manufacture method is simple, and is with low cost;
(4) tcm product of making after by fermentation is directly oral, absorb fast, curative effect is high, taste is sweet, and takes back no sequel or complication, can treat also after taking and can prevent and keep healthy.
The specific embodiment
Embodiment 1:
Chinese medicine preparation of the present invention is made (consumption is a weight portion) by following component
Scolopendra 500, Su Tuyuan (eupolyphaga a kind of, be distributed in the southern and northern wide geographic area of China, the true eupolyphoge sinensis of China, medicinal title Soviet Union eupolyphaga) 500, Gekko Swinhonis 500, Scorpio 500, Hirudo 500, awns worm 500, Cutis Bufonis 500, Radix Panacis Quinquefolii 1000, Radix Notoginseng 1000, Rhizoma Chuanxiong 1000, Spina Gleditsiae 1000, the Radix Angelicae Dahuricae 1000.
The preparation method of said components being made product of the present invention is:
(1) with the screening of above-mentioned Chinese medicinal components process, uses Scorpio or herb, remove impurity, add water and be warming up to 100 ℃, decocted 30 minutes;
(2) Chinese medicinal components after will decocting is cooled to 25 ℃, filters to obtain filtrate and medicinal residues;
(3) in last step gained filtrate, add white sugar, add white sugar and filtrate weight ratio be 1: 12, this liquid is sent into culture medium, add Zygosaccharomyces bailii, 35 ℃ of design temperatures, humidity is controlled at 30%, static cultivation 192 hours obtains oral liquid of the present invention;
(4) second step was filtered the gained medicinal residues and add white sugar water, described white sugar water is that white sugar is melted in the mixed liquor that forms in the water fully, and the weight ratio before wherein white sugar mixes with water is 1: 10, and the above-mentioned white sugar water of injection immerses to medicinal residues and wherein gets final product in medicinal residues;
(5) the 4th step gained mixture is put into culture medium, add Zygosaccharomyces bailii, 35 ℃ of design temperatures, humidity is controlled at 30%, static cultivation 216 hours, the taking-up of the mixture after the fermentation is air-dry, smash, obtain solid particle, can be directly oral, also can be used for making oral tablets or capsule.
Oral liquid, tablet or capsule are taken, three times on the one; Clinic trial Advanced Carcinoma Patient cancerous cell stops diffusion, can take food from not taking food, still in continuing to take medicine; Early, after mid-term, the patient took, effect is obvious, ill symptoms disappear or disappear, patient's antisecosis, diet be normal; Product of the present invention is obvious to the prevention and the therapeutic effect of gastric cancer, hepatocarcinoma, esophageal carcinoma, intestinal cancer, pulmonary carcinoma; And because Chinese medicine preparation Chinese crude drug cheap, and processing technology is simple, has alleviated patient's medical expense greatly, benefits the nation and the people.
Embodiment 2:
Chinese medicine preparation of the present invention is made (consumption is a weight portion) by following component
Scolopendra 550, eupolyphaga 550, Gekko Swinhonis 550, Scorpio 550, Hirudo 550, awns worm 550, Cutis Bufonis 550, Radix Panacis Quinquefolii 900, Radix Notoginseng 900, Rhizoma Chuanxiong 900, Spina Gleditsiae 900, the Radix Angelicae Dahuricae 900.
The preparation method of said components being made product of the present invention is:
(1) with the screening of above-mentioned Chinese medicinal components process, uses Scorpio or herb, remove impurity, add water and be warming up to 100 ℃, decocted 50 minutes;
(2) Chinese medicinal components after will decocting is cooled to 30 ℃, filters to obtain filtrate and medicinal residues;
(3) in last step gained filtrate, add white sugar, add white sugar and filtrate weight ratio be 1: 10, this liquid is sent into culture medium, add Zygosaccharomyces bailii, 30 ℃ of design temperatures, humidity is controlled at 25%, static cultivation 240 hours obtains oral liquid of the present invention;
(4) second step was filtered the gained medicinal residues and add white sugar water, described white sugar water is that white sugar is melted in the mixed liquor that forms in the water fully, and the weight ratio before wherein white sugar mixes with water is 1: 10, and the above-mentioned white sugar water of injection immerses to medicinal residues and wherein gets final product in medicinal residues;
(5) the 4th step gained mixture is put into culture medium, add Zygosaccharomyces bailii, 28 ℃ of design temperatures, humidity is controlled at 25%%, static cultivation 240 hours, the taking-up of the mixture after the fermentation is air-dry, smash, obtain solid particle, can be directly oral, also can be used for making oral tablets or capsule.
The using method of products obtained therefrom is with embodiment 1.
Embodiment 3
Chinese medicine preparation of the present invention is made (consumption is a weight portion) by following component
Scolopendra 510, eupolyphaga 515, Gekko Swinhonis 518, Scorpio 516, Hirudo 516, awns worm 513, Cutis Bufonis 520, Radix Panacis Quinquefolii 950, Radix Notoginseng 960, Rhizoma Chuanxiong 960, Spina Gleditsiae 950, the Radix Angelicae Dahuricae 960.
The preparation method of said components being made product of the present invention is:
(1) with the screening of above-mentioned Chinese medicinal components process, uses Scorpio or herb, remove impurity, add water and be warming up to 100 ℃, decocted 40 minutes;
(2) Chinese medicinal components after will decocting is cooled to 28 ℃, filters to obtain filtrate and medicinal residues;
(3) in last step gained filtrate, add white sugar, add white sugar and filtrate weight ratio be 1: 11, this liquid is sent into culture medium, add Zygosaccharomyces bailii, 33 ℃ of design temperatures, humidity is controlled at 28%, static cultivation 210 hours obtains oral liquid of the present invention;
(4) second step was filtered the gained medicinal residues and add white sugar water, described white sugar water is that white sugar is melted in the mixed liquor that forms in the water fully, and the weight ratio before wherein white sugar mixes with water is 1: 10, and the above-mentioned white sugar water of injection immerses to medicinal residues and wherein gets final product in medicinal residues;
(5) the 4th step gained mixture is put into culture medium, add Zygosaccharomyces bailii, 35 ℃ of design temperatures, humidity is controlled at 30%, static cultivation 224 hours, the taking-up of the mixture after the fermentation is air-dry, smash, obtain solid particle, can be directly oral, also can be used for making oral tablets or capsule.
The using method of products obtained therefrom is with embodiment 1.
The explanation of above embodiment only is used to understand principle of the present invention, is not understood to limitation of the present invention.
Claims (6)
1. Chinese medicine medicine for preventing prescription and products thereof preparation technology, it is characterized in that: Chinese medicine preparation is made (consumption is a weight portion) by following component
Scolopendra 500～550, eupolyphaga 500～550, Gekko Swinhonis 500～550, Scorpio 500～550, Hirudo 500～550, awns worm 500～550, Cutis Bufonis 500～550, Radix Panacis Quinquefolii 900～1000, Radix Notoginseng 900～1000, Rhizoma Chuanxiong 900～1000, Spina Gleditsiae 900～1000, the Radix Angelicae Dahuricae 900～1000.
2. Chinese medicine medicine for preventing prescription according to claim 1 and products thereof preparation technology, it is characterized in that: Chinese medicine preparation is made (consumption is a weight portion) by following component
Scolopendra 500, eupolyphaga 500, Gekko Swinhonis 500, Scorpio 500, Hirudo 500, awns worm 500, Cutis Bufonis 500, Radix Panacis Quinquefolii 1000, Radix Notoginseng 1000, Rhizoma Chuanxiong 1000, Spina Gleditsiae 1000, the Radix Angelicae Dahuricae 1000.
3. Chinese medicine medicine for preventing prescription according to claim 1 and products thereof preparation technology, it is characterized in that: Chinese medicine preparation is made (consumption is a weight portion) by following component
Scolopendra 510, eupolyphaga 515, Gekko Swinhonis 518, Scorpio 516, Hirudo 516, awns worm 513, Cutis Bufonis 520, Radix Panacis Quinquefolii 950, Radix Notoginseng 960, Rhizoma Chuanxiong 960, Spina Gleditsiae 950, the Radix Angelicae Dahuricae 960.
4. Chinese medicine medicine for preventing prescription according to claim 2 and products thereof preparation technology, it is characterized in that: eupolyphaga is Su Tuyuan in the Chinese medicine preparation.
5. Chinese medicine medicine for preventing prescription and products thereof preparation technology, it is characterized in that: the preparation method of described Chinese medicinal components being made product is
(1) with the screening of above-mentioned Chinese medicinal components process, uses Scorpio or herb, remove impurity, add water and be warming up to 100 ℃, decocted 30～50 minutes;
(2) Chinese medicinal components after will decocting is cooled to 25～30 ℃, filters to obtain filtrate and medicinal residues;
(3) in last step gained filtrate, add white sugar, add white sugar and filtrate weight ratio be 1: 10～1: 12, this liquid is sent into culture medium, add Zygosaccharomyces bailii, 30～35 ℃ of design temperatures, humidity is controlled at 25%～30%, and static cultivation 192～240 hours obtains oral liquid of the present invention;
(4) second step was filtered the gained medicinal residues and add white sugar water, described white sugar water is that white sugar is melted in the mixed liquor that forms in the water fully, and the weight ratio before wherein white sugar mixes with water is 1: 10, and the above-mentioned white sugar water of injection immerses to medicinal residues and wherein gets final product in medicinal residues;
(5) the 4th step gained mixture is put into culture medium, add Zygosaccharomyces bailii, 28～35 ℃ of design temperatures, humidity is controlled at 25%～30%, and static cultivation 216～240 hours is taken out the mixture after the fermentation air-dry, smash, obtain solid particle, can be directly oral, also can be used for making oral tablets or capsule.
6. Chinese medicine medicine for preventing prescription according to claim 5 and products thereof preparation technology, it is characterized in that: the preparation method that described Chinese medicinal components is made product is
(1) with the screening of above-mentioned Chinese medicinal components process, uses Scorpio or herb, remove impurity, add water and be warming up to 100 ℃, decocted 40 minutes;
(2) Chinese medicinal components after will decocting is cooled to 28 ℃, filters to obtain filtrate and medicinal residues;
(3) in last step gained filtrate, add white sugar, add white sugar and filtrate weight ratio be 1: 11, this liquid is sent into culture medium, add Zygosaccharomyces bailii, 33 ℃ of design temperatures, humidity is controlled at 28%, static cultivation 210 hours obtains oral liquid of the present invention;
(4) second step was filtered the gained medicinal residues and add white sugar water, described white sugar water is that white sugar is melted in the mixed liquor that forms in the water fully, and the weight ratio before wherein white sugar mixes with water is 1: 10, and the above-mentioned white sugar water of injection immerses to medicinal residues and wherein gets final product in medicinal residues;
(5) the 4th step gained mixture is put into culture medium, add Zygosaccharomyces bailii, 35 ℃ of design temperatures, humidity is controlled at 30%, static cultivation 224 hours, the taking-up of the mixture after the fermentation is air-dry, smash, obtain solid particle, can be directly oral, also can be used for making oral tablets or capsule.
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| CN102861262A (en) * | 2012-09-18 | 2013-01-09 | 李保明 | Chinese medicinal composition for treating esophageal cancer |
| CN104162093A (en) * | 2014-01-15 | 2014-11-26 | 左志平 | Traditional Chinese medicinal preparation for treating breast cancer, and preparation method thereof |
| CN105535691A (en) * | 2016-02-03 | 2016-05-04 | 陈亮 | Traditional Chinese medicinal microemulsion composition with effect of lung cancer resistance and preparation method thereof |
| CN112741865A (en) * | 2021-01-20 | 2021-05-04 | 高成为 | Medicine formula for treating esophagus cancer, preparation method and application |
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Application publication date: 20111102 |