CN102204538B - Pesticide composition containing cyprodinil and pyrimethanil - Google Patents
Pesticide composition containing cyprodinil and pyrimethanil Download PDFInfo
- Publication number
- CN102204538B CN102204538B CN 201110107017 CN201110107017A CN102204538B CN 102204538 B CN102204538 B CN 102204538B CN 201110107017 CN201110107017 CN 201110107017 CN 201110107017 A CN201110107017 A CN 201110107017A CN 102204538 B CN102204538 B CN 102204538B
- Authority
- CN
- China
- Prior art keywords
- cyprodinil
- mould amine
- phonetic mould
- pyrimethanil
- days
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
Landscapes
- Agricultural Chemicals And Associated Chemicals (AREA)
Abstract
The invention discloses a pesticide composition containing cyprodinil and pyrimethanil, wherein the weight ratio of cyprodinil and pyrimethanil is 50:1-1:50, and preferably the weight ratio is 10:1-1:10; and the weight ratio of the sum of the weight of cyprodinil and pyrimethanil in the pesticide composition is 8%-80%. The pesticide composition of the invention is applicable to the control of botrytis cinerea of crops such as melons, vegetables, fruit trees, and the like. The pesticide composition of the invention has significant synergic effect, reduces using cost of the pesticide, and increases economic benefit.
Description
Technical field
The composition pesticide that the present invention relates to is take cyprodinil and phonetic mould amine as active ingredient, is used for control crop gray mold.
Background technology
In the crop growth process, easily be subject to various diseases and infect, fungal disease particularly, it is of a great variety, causes harm serious, and for a long time, chemical control is to prevent and treat the main effective means of disease.In recent years, because single drug and Irrational Use of Drugs, cause many diseases to produce pesticide resistance, such as gray mold etc., become a great problem of chemical control.Simultaneously, frequent medication causes again the increase of peasant's drug cost and the aggravation of environmental pollution.Therefore, be badly in need of the bactericide kind of efficient, low toxicity, environmental protection.
Cyprodinil, english common name Cyprodinil.Belong to the aminopyrimidine bactericide, the mechanism of action suppresses the biosynthesis of methionine, suppresses the secretion of hydrolase.Absorbed rapidly by blade in plant corpus, be penetrated into more than 30% in the tissue, protected sediment is stored in the blade; transmit in xylem, also transmit between blade, at high temperature metabolism is relatively rapid; sediment quite stable under the low temperature in blade, the metabolite inanimate object is active.Same triazole type, imidazoles, morpholine class, phenylpyrrole class etc. are without cross resistance.To crop safety, without poisoning.Gray mold there is special efficacy.
Phonetic mould amine, english common name Pyrimethanil.Belong to the anilino-pyrimidine series bactericidal agent.Be the current higher bactericide of gray mold activity of preventing and treating, have prevention, protection and therapeutic action, thereby the generation of contaminating enzyme by suppressing germ stops infecting of germ and kill pathogens.Effective to the ash arrhizus bacteria that non-anilino-pyrimidine (benzimidazole and carbamic acid lipid) bactericide commonly used has developed immunity to drugs.Have simultaneously interior suction conduction and fumigation action, the spraying such as flower, young fruit that reaches rapidly plant after the dispenser position kill pathogens that is beyond one's reach, drug effect is faster, more stable.To temperature-insensitive, using under relatively low temperature does not affect drug effect.
Being mixed of different pesticide species is the common methods of the agriculture resistance disease of control.By the formulation of pesticide screening, filter out rational prescription, but the actual control efficiency of Effective Raise reduces dosage, reduces cost, delays the generation of disease drug resistance, is the important means of the disease comprehensive regulation.Cyprodinil and phonetic mould amine are mixed gray mold are had obvious synergistic effect, can effectively prevent and treat gray mold.
Summary of the invention
Technical problem to be solved: the object of the present invention is to provide a kind of efficient, low toxicity, environmental protection and lasting period long, be conducive to the composition pesticide that contains cyprodinil and phonetic mould amine of comprehensive regulation crop gray mold.
Technical scheme: a kind of composition pesticide that contains cyprodinil and phonetic mould amine, the ratio of weight and number of cyprodinil and phonetic mould amine is 50:1～1:50, the preferred weight portion rate is 10:1～1:10, and cyprodinil and the percentage by weight of phonetic mould amine weight summation in composition pesticide are 8%～80%.
Composition pesticide of the present invention can be selected known pesticidal preparations auxiliary element according to well known to a person skilled in the art method, is mixed with the Multiple Pesticides formulation.Composition pesticide of the present invention preferably is mixed with two kinds of environmental protection formulations such as suspending agent and water dispersible granules.
The pesticidal preparations auxiliary element that uses in the composition pesticide of the present invention comprises that solvent, dispersant, stabilizing agent, emulsifier, antifreezing agent, thickener etc. reach other and are of value to active ingredient stablizes and bring into play drug effect in preparation known substance, all be various compositions commonly used in the pesticidal preparations or that permission is used, be not particularly limited, concrete composition and consumption require to determine by simple test according to prescription.
The crop gray molds such as composition pesticide of the present invention is melon for preventing and treating, vegetables, fruit tree.
Composition pesticide of the present invention adopts the method for spraying to use usually, also can adopt as required upper other operation techniques used of agricultural.
Beneficial effect: 1, composition pesticide of the present invention, in certain ratio range, show obvious synergistic effect, the control efficiency of composition is significantly improved than single dose, and there is the longer lasting period, reduced simultaneously the using dosage of agricultural chemicals, reduce the medication number of times, reduced drug cost, reduced the adverse effect of agricultural chemicals to ecotope.
2, composition pesticide of the present invention, cyprodinil and two kinds of effective ingredient mechanism of action of phonetic mould amine are different, can overcome the shortcoming that long-term single use easily produces resistance, prolong the service life of medicament, to the comprehensive regulation important in inhibiting of disease resistance.
3, composition pesticide formulation of the present invention environmental protection is to crop safety.
Embodiment
In order to understand better essence of the present invention, be described further by following examples, but the present invention is not limited to these embodiment.
Composition pesticide of the present invention is that the combination of two kinds of compositions has obvious synergistic effect to the crop ash arrhizus bacteria, specifically is illustrated with following biologicall test example take cyprodinil and phonetic mould amine as active ingredient.
Embodiment 1: cyprodinil and phonetic mould amine are mixed to make up the graw mold of tomato virulence are measured.
Be mixed to the virulence of ash arrhizus bacteria for further understanding cyprodinil and phonetic mould amine, the inventor is mixed to cyprodinil and phonetic mould amine and has carried out a large amount of formulation screening tests.
Material is selected: pick up from the sick leaf of graw mold of tomato in field, and for subsequent use after the separation and purification of laboratory.
Test method: with reference to NY/T 1156.6-2006.Namely take by weighing first 97.3% cyprodinil of certain mass, the former medicine of 98.2% phonetic mould amine, adding acetone fully dissolves the Tween 80 aqueous solution dilution of rear usefulness 0.1%, is mixed with respectively the single dose mother liquor, according to the purpose that is mixed following serial proportioning (10:1/4:1/2:1/1:2/1:4/1:10) is set.Each proportioning arranges 5 concentration gradients.
Take the logarithm value of drug concentration (mg/ml) as independent variable x, take the probit value of inhibiting rate as dependent variable y, set up respectively the virulence regression equation formula, adopt DPS software to calculate the EC of single dose and each proportioning mixture
50(95% confidence limit) and the abundant method of employing Sun Yun are calculated the co-toxicity coefficient (CTC) of mixture.
According to the NY/T 1156.6-2006 bactericide synergy criteria for classifying: co-toxicity coefficient (CTC) 〉=120 shows as synergistic effect; Co-toxicity coefficient (CTC)≤80 shows as antagonism; 80＜co-toxicity coefficient (CTC)＜120 shows as summation action.
Table 1 is cyprodinil and phonetic mould amine and the different proportioning toxicity test result to botrytis cinerea (a certain pathogenic strain).
。
Can find out from result of the test table 1, the composition pesticide of cyprodinil and phonetic mould amine is between 10:1～1:10 at ratio of quality and the number of copies, and co-toxicity coefficient (CTC value) namely all shows obvious synergistic effect all greater than 120.Proof cyprodinil and phonetic mould amine are mixed and have reasonability and feasibility.
Composition pesticide of the present invention can be selected known pesticidal preparations auxiliary element according to well known to a person skilled in the art method, is mixed with the Multiple Pesticides formulation.Composition pesticide of the present invention preferably is mixed with two kinds of environmental protection formulations such as suspending agent and water dispersible granules.
Embodiment 2(the phonetic mould amine suspending agent of 50% cyprodinil).
Following material all is weight percentage: cyprodinil 25%, phonetic mould amine 25%, emulsifier fatty alcohol-polyoxyethylene ether 4%, calcium dodecyl benzene sulfonate 5%, triphenyl vinyl phenol polyoxyethylene poly-oxygen propylene aether 3%, defoamer epoxidized soybean oil 1%, antifreezing agent glycerine 0.5%, surplus are deionized water.Above-mentioned prescription is added in the mixing kettle in proportion successively, after high shear, stir and namely make the phonetic mould amine suspending agent of 50% cyprodinil.
This embodiment is used for the control graw mold of tomato, and 60 g/acres of phonetic mould amine suspending agent preparation dosages of 50% cyprodinil are watered spraying, and 7 days, 14 days preventive effects are 85.8%, 93.9% behind the medicine.60 g/acres of 50% cyprodinil water-dispersible grain agent formulation dosages are watered spraying, and 7 days, 14 days preventive effects are 71.4%, 80.1% behind the medicine.75 g/acres of 40% phonetic mould amine suspending agent preparation dosages are watered spraying, and 7 days, 14 days preventive effects are 72.2%, 82.3% behind the medicine.
The phonetic mould amine suspending agent control graw mold of tomato successful of 50% cyprodinil is better than 50% cyprodinil water dispersible granules and 40% phonetic mould amine suspending agent, illustrate that cyprodinil of the present invention and phonetic mould amine composition are better than single dose, improved actual control efficiency, reduce drug cost, delayed the generation of disease drug resistance.
Embodiment 3(45% cyprodinil pyrimethanil water dispersible granule).
Following material all is weight percentage: cyprodinil 15%, and phonetic mould amine 30%, wetting agent lauryl sodium sulfate 6%, dispersant polycarboxylate 4%, disintegrant sodium chloride 2%, binding agent polyethylene glycol 3%, stabilizing agent soluble starch 3%, surplus is carrier kaolin.Dry pulverization process, granulation, drying, screening make 45% cyprodinil pyrimethanil water dispersible granule in proportion with above-mentioned prescription.
This embodiment is used for the control gray mold of cucumber, and 60 g/has of 45% cyprodinil pyrimethanil water dispersible granule preparation dosages are watered spraying, and 7 days, 14 days preventive effects are 82.1%, 92.5% behind the medicine.60 g/acres of 50% cyprodinil water-dispersible grain agent formulation dosages are watered spraying, and 7 days, 14 days preventive effects are 74.2%, 81.6% behind the medicine.75 g/acres of 40% pyrimethanil water dispersible granule preparation dosages are watered spraying, and 7 days, 14 days preventive effects are 74.6%, 82.1% behind the medicine.
45% cyprodinil pyrimethanil water dispersible granule control gray mold of cucumber successful is better than 50% cyprodinil water dispersible granules and 40% pyrimethanil water dispersible granule, illustrate that cyprodinil of the present invention and phonetic mould amine composition are better than single dose, improved actual control efficiency, reduce drug cost, delayed the generation of disease drug resistance.
Embodiment 4(25% cyprodinil pyrimethanil water dispersible granule).
Following material all is weight percentage: cyprodinil 5%, phonetic mould amine 20%, wetting agent Negel 5%, dispersant sodium lignin sulfonate 2%, lauryl sodium sulfate 4%, disintegrant urea 4%, binding agent polyethylene glycol 3%, stabilizing agent soluble starch 3%, surplus are carrier kaolin.Dry pulverization process, granulation, drying, screening make 25% cyprodinil pyrimethanil water dispersible granule in proportion with above-mentioned prescription.
This embodiment is used for the control grape grey mould, and 120 g/has of 25% cyprodinil pyrimethanil water dispersible granule preparation dosages are watered spraying, and 7 days, 14 days preventive effects are 85.3%, 92.7% behind the medicine.60 g/acres of 50% cyprodinil water-dispersible grain agent formulation dosages are watered spraying, and 7 days, 14 days preventive effects are 76.2%, 80.8% behind the medicine.75 g/acres of 40% pyrimethanil water dispersible granule preparation dosages are watered spraying, and 7 days, 14 days preventive effects are 71.3%, 84.0% behind the medicine.
25% cyprodinil pyrimethanil water dispersible granule control grape grey mould successful is better than 50% cyprodinil water dispersible granules and 40% pyrimethanil water dispersible granule, illustrate that cyprodinil of the present invention and phonetic mould amine composition are better than single dose, improved actual control efficiency, reduce drug cost, delayed the generation of disease drug resistance.
Embodiment 5(the phonetic mould amine suspending agent of 11% cyprodinil).
Following material all is weight percentage: cyprodinil 1%, phonetic mould amine 10%, emulsifier fatty alcohol-polyoxyethylene ether 3%, calcium dodecyl benzene sulfonate 4%, triphenyl vinyl phenol polyoxyethylene poly-oxygen propylene aether 2%, defoamer epoxidized soybean oil 1%, antifreezing agent glycerine 0.5%, surplus are deionized water.Above-mentioned prescription is added in the mixing kettle in proportion successively, after high shear, stir and namely make the phonetic mould amine suspending agent of 11% cyprodinil.
This embodiment is used for the control grey mould fruit rot of strawberry, and 270 g/acres of phonetic mould amine suspending agent preparation dosages of 11% cyprodinil are watered spraying, and 7 days, 14 days preventive effects are 82.3%, 92.7% behind the medicine.60 g/acres of 50% cyprodinil water-dispersible grain agent formulation dosages are watered spraying, and 7 days, 14 days preventive effects are 70.1%, 83.5% behind the medicine.75 g/acres of 40% phonetic mould amine suspending agent preparation dosages are watered spraying, and 7 days, 14 days preventive effects are 73.6%, 86.9% behind the medicine.
The phonetic mould amine suspending agent control graw mold of tomato successful of 50% cyprodinil is better than 50% cyprodinil water dispersible granules and 40% phonetic mould amine suspending agent, illustrate that cyprodinil of the present invention and phonetic mould amine composition are better than single dose, improved actual control efficiency, reduce drug cost, delayed the generation of disease drug resistance.
Embodiment 6(80% cyprodinil pyrimethanil water dispersible granule)
Following material all is weight percentage: cyprodinil 70%, phonetic mould amine 10%, wetting agent sodium lignin sulfonate 2%, dispersant naphthalenesulfonic acid-formaldehyde condensate 4%, disintegrant sodium chloride 3%, binding agent polyethylene glycol 2%, stabilizing agent soluble starch 2%, surplus are carrier kaolin.Dry pulverization process, granulation, drying, screening make 80% cyprodinil pyrimethanil water dispersible granule in proportion with above-mentioned prescription.
This embodiment is used for the control Botrytis cinerea, and 30 g/has of 80% cyprodinil pyrimethanil water dispersible granule preparation dosages are watered spraying, and 7 days, 14 days preventive effects are 87.0%, 94.4% behind the medicine.60 g/acres of 50% cyprodinil water-dispersible grain agent formulation dosages are watered spraying, and 7 days, 14 days preventive effects are 75.4%, 81.2% behind the medicine.75 g/acres of 40% pyrimethanil water dispersible granule preparation dosages are watered spraying, and 7 days, 14 days preventive effects are 74.0%, 85.7% behind the medicine.
80% cyprodinil pyrimethanil water dispersible granule control grape grey mould successful is better than 50% cyprodinil water dispersible granules and 40% pyrimethanil water dispersible granule, illustrate that cyprodinil of the present invention and phonetic mould amine composition are better than single dose, improved actual control efficiency, reduce drug cost, delayed the generation of disease drug resistance.
Claims (2)
1. composition pesticide that contains cyprodinil and phonetic mould amine, it is characterized in that percentage by weight: cyprodinil 25%, phonetic mould amine 25%, emulsifier fatty alcohol-polyoxyethylene ether 4%, calcium dodecyl benzene sulfonate 5%, triphenyl vinyl phenol polyoxyethylene poly-oxygen propylene aether 3%, defoamer epoxidized soybean oil 1%, antifreezing agent glycerine 0.5%, surplus is deionized water, makes the phonetic mould amine suspending agent of 50% cyprodinil.
2. a kind of composition pesticide that contains cyprodinil and phonetic mould amine according to claim 1 is characterized in that preventing and treating the application on the graw mold of tomato.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 201110107017 CN102204538B (en) | 2011-04-27 | 2011-04-27 | Pesticide composition containing cyprodinil and pyrimethanil |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 201110107017 CN102204538B (en) | 2011-04-27 | 2011-04-27 | Pesticide composition containing cyprodinil and pyrimethanil |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN102204538A CN102204538A (en) | 2011-10-05 |
| CN102204538B true CN102204538B (en) | 2013-01-09 |
Family
ID=44693814
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN 201110107017 Active CN102204538B (en) | 2011-04-27 | 2011-04-27 | Pesticide composition containing cyprodinil and pyrimethanil |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN102204538B (en) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104322497A (en) * | 2014-10-15 | 2015-02-04 | 济南凯因生物科技有限公司 | Sterilization composition capable of preventing and treating grape gray mould blight |
| CN105794806A (en) * | 2016-05-13 | 2016-07-27 | 重庆云沃生态农业有限公司 | Composition for preventing and treating Chinese prickly ash diseases and application method thereof |
Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1255830A (en) * | 1997-05-15 | 2000-06-07 | 诺瓦提斯公司 | Fungicidal combinations comprising 4-phenoxyquinoline |
| CN100548122C (en) * | 2004-08-12 | 2009-10-14 | 辛根塔参与股份公司 | Fungicidal composition |
| CN101690489A (en) * | 2009-06-26 | 2010-04-07 | 深圳诺普信农化股份有限公司 | Bactericidal composition |
| CN101755782A (en) * | 2009-11-23 | 2010-06-30 | 陈章艳 | Bactericide composition containing cyprodinil |
-
2011
- 2011-04-27 CN CN 201110107017 patent/CN102204538B/en active Active
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1255830A (en) * | 1997-05-15 | 2000-06-07 | 诺瓦提斯公司 | Fungicidal combinations comprising 4-phenoxyquinoline |
| CN100548122C (en) * | 2004-08-12 | 2009-10-14 | 辛根塔参与股份公司 | Fungicidal composition |
| CN101690489A (en) * | 2009-06-26 | 2010-04-07 | 深圳诺普信农化股份有限公司 | Bactericidal composition |
| CN101755782A (en) * | 2009-11-23 | 2010-06-30 | 陈章艳 | Bactericide composition containing cyprodinil |
Also Published As
| Publication number | Publication date |
|---|---|
| CN102204538A (en) | 2011-10-05 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN101999356B (en) | Sterilization composition containing fluopicolide and metalaxyl and application thereof | |
| CN104322558A (en) | Sterilization composition and applications thereof | |
| CN105010358A (en) | Bactericidal composition and application thereof | |
| CN104738066A (en) | Sterilization composition | |
| CN102204538B (en) | Pesticide composition containing cyprodinil and pyrimethanil | |
| CN103271051A (en) | Tolfenpyrad-diafenthiuron composite insecticide composition having synergism | |
| CN103329904B (en) | Sterilization composition containing bupirimate and ningnanmycin as well as application of sterilization composition | |
| CN102007929B (en) | Thifluzamide-containing bactericidal composition | |
| CN102754649B (en) | Sterilizing composition containing phenylate bi (imidazole) and epoxiconazole | |
| CN102217623B (en) | Pesticide composition containing chlorbenzuron and flubendiamide | |
| CN104542611A (en) | Bactericidal composition containing mandipropamid | |
| CN104814031B (en) | A kind of Pesticidal combination containing butene-fipronil and clothianidin | |
| CN102349523A (en) | High-efficient sterilization composition containing bupirimate | |
| CN102657179A (en) | Sterilization composition containing phenylate diazole and trifloxystrobin | |
| CN102293200A (en) | Sterilization composition containing zoxamide and copper pimaric acid | |
| CN102484992A (en) | Synergetic pesticide composition of nimbin and tea saponin | |
| CN106508911B (en) | A kind of bactericidal composition containing cyprodinil and amino-oligosaccharide | |
| CN105340914A (en) | Sterilization composition containing benziothiazolinone and bromothalonil | |
| CN104798796A (en) | Bactericidal composition containing benzovindiflupyr and application thereof | |
| CN102405911A (en) | Sterilizing composition comrpising cyproconazole and abietic acid copper | |
| CN102349518B (en) | Sterilization composition containing cyproconazole and flumorph | |
| CN102246784A (en) | Antibacterial composition containing tetraconazole and pyraclostrobin | |
| CN108605948A (en) | A kind of bactericidal composition containing fluorine thiazole pyrrole ethyl ketone and amisulbrom | |
| CN105284835A (en) | Tetramycin and chlorofluoro isocyanuric acid-containing bacterial composition | |
| CN104839203B (en) | Agricultural fungicidal composition |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant |