CN102139022B - Medicament for treating lumbar intervertebral disc protrusion and rheumatism - Google Patents

Abstract

The invention discloses a medicament for treating lumbar intervertebral disc protrusion and rheumatism, relating to a medicament prepared by taking Chinese herbal medicines as raw materials. Each dose of the medicament comprises the following raw medicines in proportions by weight: 15g of pipefish, 15g of earthworm, 15g of starflowerlike loosestrife root or herb, 10g of Chinese polyphaga, 10g of nux vomica, 10g of myrrh, 15g of mastic, 15g of black-tail snake, 15g of girald daphne bark, 15g of notopterygium root and 15g of radix angelicae pubescentis, wherein the nux vomica is fried in advance. The preparation method of the medicament comprises the following steps of: preparing the raw medicines according to the formula, wherein the nux vomica needs to be fried in advance; drying, crushing and mixing all raw medicines to prepare pills or tablets according to conventional processes; and qualifying to obtain products. The medicament disclosed by the invention has an obvious effect on treating lumbar intervertebral disc protrusion, rheumatism and scapulohumeral periarthritis.

Description

A kind of medicine of treating prolapse of lumbar intervertebral disc and rheumatism

Technical field

The present invention relates to pharmaceutical composition, in particular to the Chinese herbal medicine being the treatment prolapse of lumbar intervertebral disc of preparation of raw material and the medicine of rheumatism.

Background technology

Prolapse of lumbar intervertebral disc is a lumbar intervertebral disc each several part (vertebral pulp, fibrous ring and cartilaginous lamina) behind degenerative lesion in various degree; Again under the extraneous factor effect; Cause fibrous ring to be broken; Vertebral pulp is outstanding and cause adjacent irriate or compressing from rent, thereby makes the waist lower limb produce the disease of symptoms such as a series of pain, numbness, acid expand.Rheumatism is meant with muscle, arthralgia to be one type of disease of master.The main connective tissue that influences health possibly be that immune system injury causes.The most patient of intervertebral disc prolapse and rheumatism is a middle-aged and elderly people, and winters in spring two Ji Yifa can influence orthobiosis of people when serious, and less patient suffering can't bear.

People have accumulated rich experience aspect the treatment prolapse of lumbar intervertebral disc.In recent years; Had many treatment prolapse of lumbar intervertebral disc and rheumatism the Chinese medicine preparation application patent of invention, for example No. 99107843.8 " a kind of Chinese medicine for outer use of treating hyperosteogeny, prolapse of lumbar intervertebral disc and all kinds of soft tissue injurys ", No. 02108893.4 " a kind of pharmaceutical formulation of treating sciatic nerve and prolapse of lumbar intervertebral disc ", No. 03160001.8 " a kind of Chinese medicine composition of treating rheumatism, rheumatoid and prolapse of lumbar intervertebral disc and preparation method thereof " and No. 200810103973.2 " a kind of Chinese medicine compositions of treating cervical spondylosis, prolapse of lumbar intervertebral disc, rheumatic arthralgia " etc.Above-mentioned Chinese medicine preparation has nothing in common with each other, and curative effect also is not quite similar.But that the traditional Chinese medical science is cured the disease is effective, be free from side effects basically.Therefore people continue to excavate Chinese material medicine resource, develop more efficiently medicine.

Summary of the invention

The object of the invention just is to provide a kind of medicine of treating prolapse of lumbar intervertebral disc and rheumatism, makes the patient can remove the puzzlement of prolapse of lumbar intervertebral disc or rheumatism fast, obtains better therapeutic effect.

The component and the quality of each agent product of medicine of treatment prolapse of lumbar intervertebral disc that the inventor provides and rheumatism are following: Solenognathus 15g, Pheretima 15g, Lysimachia trientaloides Hemsl. 15g, Eupolyphaga Seu Steleophaga 10g, Semen Strychni 10g, Myrrha 10g, Olibanum 15g, Zaocys 15g, Daphne giraldii Nitsche 15g, Rhizoma Et Radix Notopterygii 15g, Radix Angelicae Pubescentis 15g.

In the said components, Semen Strychni is parch in advance.

In the above-mentioned Chinese crude drug, Solenognathus is removed all of epithelium and internal organs for Syngnathidae animal solenognathus hardwickii (Solenognahus hardwickii), and salty in the mouth is sweet, and is warm in nature, and the effect (seeing Jiangsu new medical college volume " Chinese medicine voluminous dictionary " P1925) of kidney invigorating and YANG supporting is arranged; Pheretima; Be Lumbricus, all, cold in nature for huge earthworm section's animal Pheretima aspergillum (Pheretimaaspergillum) or the dark different lip earthworm of Lumbricidae animal back (Allolobophora trapezoides); Distinguish the flavor of ability heat clearing away, suppressing the hyperactive liver, Zhichuan, collateral dredging (seeing " Chinese medicine voluminous dictionary " 2111 pages); Lysimachia trientaloides Hemsl. is the root or the herb of the narrow leaf Herba lysimachiae capillipedis of Primulaceae plant (Lusimachia trientaloides), and acrid in the mouth is warm in nature, and the effect (seeing " Chinese medicine voluminous dictionary " P1688) of dispeling the wind, invigorating blood circulation is arranged; Eupolyphaga Seu Steleophaga; I.e.

worm; Be the female whole insect of Corydiidae insecticide eupolyphoge sinensis (Eupolyphaga sinensis), cold in nature, salty in the mouth; Poisonous, ability inducing diuresis to remove edema removing blood stasis, removing mass, collateral dredging, reason are hindered (seeing " Chinese medicine voluminous dictionary " 2684 pages); Semen Strychni, cold in nature for the mature seed of loganiaceae plant Semen Strychni (Strychnos nux-vomica), bitter in the mouth, poisonous, diffusing heat in blood, detumescence, analgesic effect (seeing " Chinese medicine voluminous dictionary " 291 pages) are arranged; Myrrha is the gum resin of olive subject plant myrrh (Commiphora myrrha), and property is flat, and bitter in the mouth has diffusing wind blood stasis dispelling, subduing swelling and relieving pain effect (seeing " Chinese medicine voluminous dictionary " P1167); Olibanum, warm in nature for the gum resin of olive subject plant cassette Boswellia carterii (Boswellia earterii), acrid in the mouth is bitter, has regulating qi and activating blood, analgesic therapy, chases after malicious effect (seeing " Chinese medicine voluminous dictionary " P1379); Zaocys, promptly Zaocys is removed all of internal organs for Colubridae animal Zaocys (Zaocys dhumnades), and sweet in the mouth becomes, and property is flat, and the effect (seeing " Chinese medicine voluminous dictionary " P466) of wind-damp dispelling, the meridian dredging is arranged; Daphne giraldii Nitsche is root bark or the peel of stem of thymelaeceae plant Daphne Giraldii Nitsche (Daphne giraldii), and acrid in the mouth is bitter, and is warm in nature, ability invigorating middle warmer, profit expelling wind and removing dampness, pain relieving dissipating blood stasis (seeing " Chinese medicine voluminous dictionary " P1739); Rhizoma Et Radix Notopterygii is the root and rhizome of samphire Rhizoma Et Radix Notopterygii (Notopterygium incisum), and acrid in the mouth is bitter, and is warm in nature, ability wind-damp dispelling, sharp joint (seeing " Chinese medicine voluminous dictionary " P1172); Radix Angelicae Pubescentis is the root and rhizome of samphire Angelica pubescens (Angelica pubesces), and acrid in the mouth is bitter, and is warm in nature, can dispel the wind, win wet, cold expelling, pain relieving (seeing " Chinese medicine voluminous dictionary " P1705).Above-mentioned medical material should meet " the regulation in one one of the Chinese pharmacopoeia nineteen ninety-five version under each medical material item.

The method for preparing of the medicine of treatment prolapse of lumbar intervertebral disc of the present invention and rheumatism is to be equipped with medicine by the Chinese medicine of respectively distinguishing the flavor of in the prescription, and wherein, Semen Strychni is parch in advance; With above-mentioned whole medicine oven dry, pulverizing, mixing, process pill or tablet again, after the assay was approved, can pack and dispatch from the factory according to common process.Product should meet " requirement in one one of the Chinese pharmacopoeia nineteen ninety-five version, product index is following: it is 2.0g that every ball contains former medicine, and content uniformity is at 2.0g ± 10%; Moisture must not surpass 9.0%.

The drug usage of treatment prolapse of lumbar intervertebral disc of the present invention and rheumatism is oral, warm water delivery service, every day 3 times, each 10～12g (5～6 ball).Also can take the circumstances into consideration to add and subtract dose according to the state of an illness.

This Chinese medicine is evident in efficacy, and in clinical practice 6 years, wherein treat prolapse of lumbar intervertebral disc 51 examples, 47 examples are cured, 3 examples effectively, 1 example is invalid; Treatment scapulohumeral periarthritis 27 examples, 25 examples are cured, and 2 examples are effectively; Treatment rheumatalgia 79 examples all produce effect.Wherein more typical case has: (1) Ma Zhiwen, people from town of Linkou County, Bijie City, its wife suffers from prolapse of lumbar intervertebral disc in January, 2010, walking disorder, pain unbearably, the Duo Jia hospitalize does not all have improvement through Guangdong.After take 3 doses of this medicines upon somebody's introduction after the state of an illness take a turn for the better gradually, continue to take 10 doses, the state of an illness is cured basically, obeys 3 doses again, consolidates effect, does not find pain in nearly 1 year, the work of normally going to work.Telephone number: 15599388882.(2) Chen Xu, 30 years old, the prosperous village people in Dafang County, Guizhou Province found that bipod is ached, the Duo Jia examination in hospital is prolapse of lumbar intervertebral disc through Kweiyang in May, 2009, after take 12 doses of this medicines, the state of an illness is effectively controlled, and is painless, followed up a case by regular visits to 1 year, recurrence, all are normal.Telephone number: 137765858515.(3) Han Bing, the man, 37 years old, lake, Bijie City street personage felt that shoulder was uncomfortable in 2005 suddenly, and pain is arranged, both hands are unable, are scapulohumeral periarthritis through hospital diagnosis, after take 5 doses of this medicines, all cure, had a surplus in 4 years at present, follow up a case by regular visits to, recurrence.Telephone number: 08578612614.(4) Zhou Laoliu, Dafang County, 57 years old Guizhou Shuan Shan people from town finds myasthenia of limbs, pain in May, 2007.After how tame hospital diagnosis is a seriousness rheumatism, once took prednisone, Phenylbutazone is with pain management.But drug effect later again pain unbearably, after upon somebody's introduction, take recovery from illness behind 7 doses of this medicines, existing recurrence.

This medicine is applicable to treatment prolapse of lumbar intervertebral disc, rheumatism, scapulohumeral periarthritis, and is evident in efficacy.

The specific embodiment

Embodiment gets Solenognathus 15g, Pheretima 15g, Lysimachia trientaloides Hemsl. 15g, Eupolyphaga Seu Steleophaga 10g, Semen Strychni 10g, Myrrha 10g, Olibanum 15g, Zaocys 15g, Daphne giraldii Nitsche 15g, Rhizoma Et Radix Notopterygii 15g, Radix Angelicae Pubescentis 15g, totally 11 flavor medical materials.Wherein, Semen Strychni parch in advance; With above-mentioned whole medicine oven dry, pulverizing, mixing, process pill again, after the assay was approved, can pack and dispatch from the factory according to common process.Product should meet " requirement in one one of the Chinese pharmacopoeia nineteen ninety-five version, product index is following: it is 2.0g that every ball contains former medicine, and content uniformity is at 2.0g ± 10%; Moisture must not surpass 9.0%.

Claims (3)

1. a medicine of treating prolapse of lumbar intervertebral disc and rheumatism is characterized in that the component and the constituent mass of each agent product of this medicine is following: Solenognathus 15g, Pheretima 15g, Lysimachia trientaloides Hemsl. 15g, Eupolyphaga Seu Steleophaga 10g, Semen Strychni (parched) 10g, Myrrha 10g, Olibanum 15g, Zaocys 15g, Daphne giraldii Nitsche 15g, Rhizoma Et Radix Notopterygii 15g, Radix Angelicae Pubescentis 15g.

2. medicine as claimed in claim 1 is characterized in that in the said component, and Semen Strychni is parch in advance.

3. the method for the medicine of preparation said treatment prolapse of lumbar intervertebral disc of claim 1 and rheumatism is characterized in that being equipped with medicine by the Chinese medicine of respectively distinguishing the flavor of in the prescription, and wherein, Semen Strychni is parch in advance; With above-mentioned whole medicine oven dry, pulverizing, mixing, process pill or tablet again, after the assay was approved, can pack and dispatch from the factory according to common process.