CN102138870B - Collagen facial mask and preparation method thereof - Google Patents
Collagen facial mask and preparation method thereof Download PDFInfo
- Publication number
- CN102138870B CN102138870B CN2011100790139A CN201110079013A CN102138870B CN 102138870 B CN102138870 B CN 102138870B CN 2011100790139 A CN2011100790139 A CN 2011100790139A CN 201110079013 A CN201110079013 A CN 201110079013A CN 102138870 B CN102138870 B CN 102138870B
- Authority
- CN
- China
- Prior art keywords
- collagen protein
- skin
- collagen
- oil
- acid
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
Landscapes
- Cosmetics (AREA)
Abstract
The invention provides a collagen facial mask and a preparation method thereof. The method comprises the following steps of: stirring 1 to 20 mass percent of aqueous solution of collagen and 0.1 to 2 mass percent of aqueous solution of a modifier at the temperature of between 20 and 60 DEG C for reacting for 15 to 45 minutes to obtain stock solution; adding a plasticizer, a functional additive and an antimicrobial growth promoter into the stock solution, and continuing to stir at the temperature of between 20 and 60 DEG C for 30 to 60 minutes to obtain mixed solution; and pouring the mixed solution into a die for forming, and drying at the temperature of between 30 and 60 DEG C for 3 to 10 hours to obtain the collagen facial mask. The prepared collagen facial mask is mainly formed by macromolecular substances extracted from natural animals and plants, safe and effective and does not have toxic or side effect, has the high heat stability, toughness, ductility and adhesion, and can be in fit with skin well and achieve the effects of preserving moisture doubly, softening cutin skin, resisting winkle, whitening the skin, restoring the skin and the like under the assistance of the functional additive; rejected materials of the facial mask are degradable, and do not cause environmental pollution; and the collagen facial mask can be widely applied in the field of daily cosmetics and has the excellent market application prospect.
Description
Technical field
The present invention relates to cosmetics and technology of preparing thereof,, belong to the daily cosmetics field in particular to a kind of collagen protein face and preparation method thereof.
Background technology
Along with improving constantly of science and technology development and living standards of the people, in occupation of more and more important position, this has also driven the development of cosmetic chemistry to cosmetics in people's life.In recent years, the kind of cosmetics is on the increase, and it is functional also more and more stronger, and scientific and technological content is also increasingly high simultaneously.Facial film has also obtained significant progress as one of mainstream product of cosmetics.
Facial film is divided into two kinds of not molding facial film and molding facial films, and wherein not molding facial film is divided into cream pack and powder face pack again.Cream pack and powder face pack use all very inconvenient, and the medicated clothing of making dirty easily.The molding facial film is divided into four kinds: Face film towel or face paper, cellulose derivative class facial film, mask type nutrient face-pack and finished product facial film.Although the modulation of more not molding of molding facial film facial film is simply many, still can bring inconvenience to user: 1, the ductility of facial film is bad, is difficult to meet fully everyone face shape characteristic; 2, because the viscosity of facial film depends on the support material that it is used, so the performance of facial film also receives the influence of its required specific support raw material; 3, not enough and fit that not exclusively to cause being similar to not molding facial film the same owing to viscosity, can not be when peeling off with the oils and fats on the skin, perspiration and dirt along with facial film is removed together; 4, the carrier and other raw materials that use, expensive like prices such as hyaluronic acids, cost is higher.
Collagen protein is that occurring in nature exists animal proteinum the most widely, and it has the excellent repairing effect to ultraviolet damage, and it has excellent compatibility, stability and antibiotic property in cosmetic formulations.In addition, collagen protein and skin have the fabulous adsorptivity and the compatibility, the function that has the blocking-up brown pigment to generate.Simultaneously, contain hydrophilic groups such as amino, hydroxyl in the collagen hydrolysate polypeptide chain, human body skin is had moisture-keeping function.In addition, the use of collagen protein combination skin care item late frost has the skin-active reparation and preserves moisture and lock water, quicken cellular replication propagation, significantly improve cuticular accretion rate, reparation damaged cell, minimizing wrinkle increase elasticity and efficiently lock the water effect.Experiment shows that hydrolytic collagen solution also has antibacterial antiseptic effect after deliberation.But, collagen protein itself has the shortcoming of mechanical performance and poor heat stability, has limited its application.Normally used collagen-base biomaterial all will pass through modification, to improve the performance of collagen protein materialization aspect.
What collagen-modified method application was more is chemical crosslinking, and modifier mainly is glutaraldehyde, Carbodiimides and epoxy compounds.And glutaraldehyde and proteic course of reaction are reversible, generate the structural instability of schiff alkali, are easy to the hydrolysis generation and have the toxic free micromolecule aldehyde of metabolism (CN1861801A).In addition, method of modifying commonly used also has with collagen protein and other natural macromolecular material blend, like collagen protein and carboxymethyl cellulose blend (CN1456146A).Though blend can improve the intensity of collagen protein by secondary keys such as hydrogen bonds; And increase the advantageous property that many collagen protein do not have, but the collagen protein membrane material of this method modification is in the requirement of the aspect still can not satisfy face-mask material such as mechanical property, heat stability, resistance be moist.
The modifier dialdehyde polysaccharide that the present invention uses has the advantage of nontoxic, biodegradable, regenerated raw materials, and contains a large amount of reactive group aldehyde radicals in the molecular structure, and is high with the reactivity of collagen protein, is a kind of ideal collagen-modified dose.And up to the present, there are not pertinent literature or invention that report was carried out in this research as yet.
Summary of the invention
Simple collagen protein face heat stability is low, toughness, ductility and adhesive are poor; Can not satisfy the serviceability of facial film preferably; And traditional method of modifying may hydrolysis produces the toxic free micromolecule aldehyde of metabolism arranged, and the invention provides a kind of novel collagen facial film and preparation method thereof for this reason.
The present invention realizes that through following technical scheme except that specifying, related umber is parts by weight, and percentage ratio is percetage by weight.The invention provides a kind of collagen protein face, the method for preparing of this facial film is specific as follows:
(1) prepares mass fraction respectively and be the collagen protein aqueous solution of (1～20) % and the modifier aqueous solution of mass fraction,, and, prepare stock solution in 20 ~ 60 ℃ of stirring reactions of temperature 15 ~ 45 minutes then with two kinds of solution mixing for (0.1～2) %;
(2) in above-mentioned stock solution, add plasticizer, functional additive and antimicrobial growth stimulator, continue for 20 ~ 60 ℃ to stir 30 ~ 60 minutes in temperature afterwards, prepare mixed solution;
(3) pour above-mentioned mixed solution into die for molding,, take off film and promptly obtain collagen protein face in 30 ~ 60 ℃ of dryings of temperature 3 ~ 10 hours.
In above-mentioned technological case, said modifier is 2, and the 3-o-dihydroxy is oxidized to dialdehyde, and aldehyde group content is the dialdehyde polysaccharide of (50～99) %.
The said polysaccharide of the modifier that uses among the present invention is any one or a few mixture in starch, cellulose, methylcellulose, ethyl cellulose, hydroxyethyl-cellulose, hydroxypropyl cellulose, the carboxymethyl cellulose.
In above-mentioned technological case, the ratio of modifier and collagen protein counts 1 by dry weight: (10～800).
In order to improve the toughness of facial film provided by the invention, need to add a certain amount of plasticizer.The operable plasticizer of the present invention is any one or a few mixture in glycerol, propylene glycol, mannitol, sorbitol, xylitol, maltose alcohol, spermol, monoglyceride, epoxy soybean oil, Oleum Cocois, hydrogenated lanolin, castor oil hydrogenated, Methanamide, the liquid paraffin.
In above-mentioned technological case, the ratio of plasticizer and collagen protein counts 1 by dry weight: (2～30).
In order to reach the object of the invention, also need add functional additive in the stock solution, said functional additive is any one or a few mixture in skin wetting agent, skin whitening agent, keratolytic, external skin wrinkling-preventing agent, skin renovation agent, the aromatic.
Wherein said skin wetting agent is any one or a few mixture in chondroitin sulfate, chitosan, chitin, casein, soybean protein, zein, wheat gluten protein, lactalbumin, elastin, lactic acid, hyaluronic acid, the sodium alginate;
Described skin whitening agent is a vitamin B
3, any one or a few mixture in the vitamin C, beta-carotene, Oleum Hippophae, fruit acid, ascorbic acid, gallic acid, kojic acid, arbutin;
Described keratolytic is any one or a few mixture in lanoline, Jojoba oil, Oleum Helianthi, Oleum Vitis viniferae, safflower oil, Radix Oenotherae erythrosepalae oil, squalane, the dissolving keratinase;
Described external skin wrinkling-preventing agent is any one or a few mixture in nicotinic acid, nicotiamide, D-pantothenic acid, the vitamin E;
Described skin renovation agent is any one or a few mixture in Radix Hamamelidis Mollis extract, Aloe extract, allantoin, salicylic acid, lactic acid, glycyrrhizic acid, the ethanol;
Described aromatic is any one or a few mixture in Salvia farinacea oil, Flos Rosae Rugosae quintessence oil, Flos Matricariae chamomillae quintessence oil, Herba Lysimachiae foenum-graeci quintessence oil, tea tree ethereal oil, Bergamot, Fructus Citri Limoniae quintessence oil, Semen pruni armeniacae oil, the Herba Menthae quintessence oil.
In above-mentioned technological case, the ratio of functional additive and collagen protein counts 1 by dry weight: (5～1000).
In order to improve the antibacterial ability of facial film provided by the invention, also need add a certain amount of antimicrobial growth stimulator.The operable said antimicrobial growth stimulator of the present invention is any one or a few mixture in Oxybenzene formyl tetracycline, erythromycin, clindamycin, Azelaic Acid, phenyl phenol, benzylalcohol, methyl parahydroxybenzoate, ethylparaben, propyl p-hydroxybenzoate, polysorbas20, tween 30, polysorbate60, the span.
Collagen protein face provided by the invention can be applicable to the daily cosmetics field.
Compared with present technology the present invention has many-sided good effect and advantage, but concrete inductive generalization is following.
(1) the present invention adopts collagen protein as primary raw material; Through adding cross-linking agent, plasticizer, functional additive and antimicrobial growth stimulator, control membrance casting condition, the modified collagen protein facial mask of directly processing; Compare with polyvinylpyrrolidone--based facial film with traditional polyvinyl alcohol; Be prone to degraded, have good environmental-protecting performance, be used for daily cosmetics and have more excellent safety.
(2) the present invention is processed by the natural animal-plant polymer substance, and is nontoxic, tasteless, non-stimulated, have no side effect; The aminoacid of collagen protein is formed identical with human body skin, thus good with skin-friendliness, affinity is strong, and has and well preserves moisture and the clean skin function of deep layer, can also replenish the collagen protein that loses in the skin.
(3) cross-linking agent that uses among the present invention is the dialdehyde polysaccharide.Dialdehyde polysaccharide reactivity is high, and the dialdehyde polysaccharide of trace can make toughness, ductility, adhesive and the heat stability of collagen protein obtain bigger improvement.The good biology performance such as the avirulence that has except itself, biodegradability, the metabolism toxicity phenomenon that adopts the collagen protein face of its preparation can avoid free micromolecule aldehyde to cause.
(4) the prepared facial film of technology of the present invention has good toughness and ductility; Can extend arbitrarily according to the different facial characteristics of user; And self have good viscosity, can be when peeling off with the oils and fats on the skin, perspiration and dirt along with facial film is removed together.
(5) functional additive that uses among the present invention not only can improve the moisture-keeping functions of collagen protein face; All right soften cuticle; Help to smooth away wrinkles, make in the facial film dry run skin appropriateness to shrink; Make that lax skin is tightened, skin whitening simultaneously and be that impaired skin obtains repairing, reach the purpose of beauty treatment.
(6) the prepared facial film of technology of the present invention can especially be fit to individual or home care adaptable across the beauty parlor.After face cleaned, take advantage of in the wet combining, perhaps facial film being sprayed water spreads on face after moistening.Need not to repose, the study that do not dally over one's work can reach ideal effect.
(7) be a kind of novel facial film with the prepared facial film of technology of the present invention, higher scientific and technological added value is arranged, have wide potential market, significant to the developmental research of daily cosmetics material, have high economic benefit and social benefit.
The specific embodiment
Provide three embodiment of the present invention below, the present invention is specifically described through embodiment.Be necessary to be pointed out that at this; Embodiment only is used for the present invention is further explained; Can not be interpreted as the restriction to protection domain of the present invention, the person skilled in the art in this field can make some nonessential improvement and adjustment according to the content of the invention described above.
In following examples, except that specifying, related umber is parts by weight, and percentage ratio is percetage by weight.
Embodiment 1
Take by weighing 1000 parts of collagen protein dry products and add in 8000 parts the water, swelling after 50 minutes under the room temperature places under 50 ℃ of left and right sides water bath condition constantly stir about to obtain mass fraction in 40 minutes and is about 11.11% collagen solution.Take by weighing 10 parts of modifier (aldehyde group content is that 90% 3 parts of wherein dialdehyde starchs, aldehyde group content are 7 parts of 74% dialdehyde methylcellulose) simultaneously and add in 990 parts the water, continuous stir about 8 hours about 25 ℃ obtains mass fraction and is about 1% modifier solution.Under 40 ℃, than being the ratio blend of 1:100, constantly stir about is 30 minutes, obtains concentration and is about 10% the proteic stock solution of modified collagen in collagen protein dry product weight in modifier and collagen protein dry weight.To modified collagen proteic stock solution in add plasticizer with collagen protein dry weight ratio for the ratio of 1:5 in plasticizer (is the ratio blend of 1:1 with xylitol dry weight ratio in propylene glycol); To modified collagen proteic stock solution in add functional additive with collagen protein dry weight ratio for the ratio of 1:50 in functional additive (is the ratio blend of 7:3 in lactic acid, fruit acid dry weight ratio) simultaneously; In the proteic stock solution of modified collagen, add an amount of antimicrobial growth stimulator again; In 50 ℃ of stir abouts 30 minutes, be configured to the mixed liquor of collagen protein, modifier, plasticizer, functional additive and antimicrobial growth stimulator.The mixed liquor of collagen protein, modifier, plasticizer, functional additive and antimicrobial growth stimulator is injected mould, be placed in the baking oven, about 60 ℃, kept about 8 hours down.Then mould is taken out, take off film and promptly obtain collagen protein face.
Embodiment 2
Take by weighing 2000 parts of collagen protein dry products and add in 97500 parts the water, swelling after 30 minutes under the room temperature places under 40 ℃ of left and right sides water bath condition constantly stir about to obtain mass fraction in 30 minutes and is about 2.01% collagen solution.Taking by weighing 10 parts of modifier (wherein aldehyde group content is that 90% 2 parts of dialdehyde starchs, aldehyde group content are that 87% 5 parts of dialdehyde celluloses, aldehyde group content are 3 parts of 82% dialdehyde ethyl celluloses) simultaneously adds in 490 parts the water; Continuous stir about is 12 hours about 25 ℃, obtains mass fraction and is about 2% modifier solution.Under 50 ℃, than being the ratio blend of 1:200, constantly stir about is 45 minutes, obtains concentration and is about 2% the proteic stock solution of modified collagen in collagen protein dry product weight in modifier and collagen protein dry weight.To modified collagen proteic stock solution in add plasticizer with collagen protein dry weight ratio for the ratio of 1:20 in plasticizer (is the ratio blend of 2:1 with epoxy soybean oil dry weight ratio in Methanamide); To modified collagen proteic stock solution in add functional additive with collagen protein dry weight ratio for the ratio of 1:20 in functional additive (is the ratio blend of 10:7:3 in casein, ascorbic acid, squalane dry weight ratio) simultaneously; In the proteic stock solution of modified collagen, add an amount of antimicrobial growth stimulator again; In 60 ℃ of stir abouts 40 minutes, be configured to the mixed liquor of collagen protein, modifier, plasticizer, functional additive and antimicrobial growth stimulator.The mixed liquor of collagen protein, modifier, plasticizer, functional additive and antimicrobial growth stimulator is injected mould, be placed in the baking oven, about 40 ℃, kept about 10 hours down.Then mould is taken out, take off film and promptly obtain collagen protein face.
Embodiment 3
Take by weighing 1500 parts of collagen protein dry products and add in 46500 parts the water, swelling after 35 minutes under the room temperature places under 50 ℃ of left and right sides water bath condition constantly stir about to obtain mass fraction in 30 minutes and is about 3.125% collagen solution.Taking by weighing 30 parts of modifier (aldehyde group content is that 90% 7 parts of dialdehyde starchs, aldehyde group content are that 85% 9 parts of dialdehyde celluloses, aldehyde group content are 14 parts of 83% dialdehyde sodium alginates) simultaneously adds in 1970 parts the water; Continuous stir about is 10 hours about 25 ℃, obtains mass fraction and is about 1.5% modifier solution.Under 40 ℃, than being the ratio blend of 1:50, constantly stir about is 45 minutes, obtains concentration and is about 3% the proteic stock solution of modified collagen in collagen protein dry product weight in modifier and collagen protein dry weight.To modified collagen proteic stock solution in add plasticizer with collagen protein dry weight ratio for the ratio of 1:5 in plasticizer (is the ratio blend of 3:1 with mannitol dry weight ratio in glycerol); To modified collagen proteic stock solution in add functional additive with collagen protein dry weight ratio for the ratio of 1:200 in functional additive (is the ratio blend of 25:13:10:2 in sodium alginate, Aloe extract, nicotinic acid, Salvia farinacea oil dry weight ratio) simultaneously; In the proteic stock solution of modified collagen, add an amount of antimicrobial growth stimulator again; In 60 ℃ of stir abouts 30 minutes, be configured to the mixed liquor of collagen protein, modifier, plasticizer, functional additive and antimicrobial growth stimulator.The mixed liquor of collagen protein, modifier, plasticizer, functional additive and antimicrobial growth stimulator is injected mould, be placed in the baking oven, about 50 ℃, kept about 8 hours down.Then mould is taken out, take off film and promptly obtain collagen protein face.
Claims (2)
1. collagen protein face is characterized in that method for preparing is following:
(1) preparing mass fraction respectively is that 1～20% collagen protein aqueous solution and mass fraction are 0.1～2% modifier aqueous solution, then two kinds of solution is mixed, and in 20 ~ 60 ℃ of stirring reactions of temperature 15 ~ 45 minutes, prepares stock solution;
(2) in above-mentioned stock solution, add plasticizer, functional additive and antimicrobial growth stimulator, continue for 20 ~ 60 ℃ to stir 30 ~ 60 minutes in temperature afterwards, prepare mixed solution;
(3) pour above-mentioned mixed solution into die for molding,, take off film and promptly obtain collagen protein face in 30 ~ 60 ℃ of dryings of temperature 3 ~ 10 hours;
Said modifier is 2, and the 3-o-dihydroxy is oxidized to dialdehyde, and aldehyde group content is 50～99% dialdehyde polysaccharide;
The ratio of said modifier and collagen protein by dry weight count 1: 10～800.
2. collagen protein face according to claim 1 is characterized in that said polysaccharide is any one or a few mixture in starch, cellulose, methylcellulose, ethyl cellulose, hydroxyethyl-cellulose, hydroxypropyl cellulose, the carboxymethyl cellulose.
3. collagen protein face according to claim 1 is characterized in that said plasticizer is any one or a few mixture in glycerol, propylene glycol, mannitol, sorbitol, xylitol, maltose alcohol, spermol, monoglyceride, epoxy soybean oil, Oleum Cocois, hydrogenated lanolin, castor oil hydrogenated, Methanamide, the liquid paraffin.
4. collagen protein face according to claim 1, the ratio that it is characterized in that plasticizer and collagen protein by dry weight count 1: 2～30.
5. collagen protein face according to claim 1 is characterized in that said functional additive is any one or a few mixture in skin wetting agent, skin whitening agent, keratolytic, external skin wrinkling-preventing agent, skin renovation agent, the aromatic;
Described skin wetting agent is any one or a few mixture in chondroitin sulfate, chitosan, chitin, casein, soybean protein, zein, wheat gluten protein, lactalbumin, elastin, lactic acid, hyaluronic acid, the sodium alginate;
Described skin whitening agent is a vitamin B
3, any one or a few mixture in the vitamin C, beta-carotene, Oleum Hippophae, fruit acid, gallic acid, kojic acid, arbutin;
Described keratolytic is any one or a few mixture in lanoline, Jojoba oil, Oleum Helianthi, Oleum Vitis viniferae, safflower oil, Radix Oenotherae erythrosepalae oil, squalane, the dissolving keratinase;
Described external skin wrinkling-preventing agent is any one or a few mixture in nicotinic acid, nicotiamide, D-pantothenic acid, the vitamin E;
Described skin renovation agent is any one or a few mixture in allantoin, salicylic acid, lactic acid, glycyrrhizic acid, the ethanol;
Described aromatic is any one or a few mixture in Salvia farinacea oil, Flos Rosae Rugosae quintessence oil, Flos Matricariae chamomillae quintessence oil, Herba Lysimachiae foenum-graeci quintessence oil, tea tree ethereal oil, Bergamot, Fructus Citri Limoniae quintessence oil, Semen pruni armeniacae oil, the Herba Menthae quintessence oil.
6. collagen protein face according to claim 1, the ratio that it is characterized in that functional additive and collagen protein by dry weight count 1: 5～1000.
7. collagen protein face according to claim 1 is characterized in that said antimicrobial growth stimulator is any one or a few mixture in Oxybenzene formyl tetracycline, erythromycin, clindamycin, Azelaic Acid, phenyl phenol, benzylalcohol, methyl parahydroxybenzoate, ethylparaben, propyl p-hydroxybenzoate, polysorbas20, tween 30, polysorbate60, the span.
8. according to the described collagen protein face of aforementioned arbitrary claim, it is characterized in that said collagen protein face can be applicable to the daily cosmetics field.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2011100790139A CN102138870B (en) | 2011-03-31 | 2011-03-31 | Collagen facial mask and preparation method thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2011100790139A CN102138870B (en) | 2011-03-31 | 2011-03-31 | Collagen facial mask and preparation method thereof |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN102138870A CN102138870A (en) | 2011-08-03 |
| CN102138870B true CN102138870B (en) | 2012-05-02 |
Family
ID=44406818
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN2011100790139A Active CN102138870B (en) | 2011-03-31 | 2011-03-31 | Collagen facial mask and preparation method thereof |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN102138870B (en) |
Families Citing this family (33)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102283792B (en) * | 2011-08-24 | 2013-01-16 | 迪特克(济源)绿色生物科技有限公司 | Natural anti-acne cream |
| CN103211739B (en) * | 2011-10-11 | 2014-06-04 | 沈志荣 | Washing-free sleep mask composition containing guava extractive, pansy flower extractive and pearl powder |
| CN102319196B (en) * | 2011-10-11 | 2013-04-17 | 沈志荣 | Washing-free sleep facial mask composition and preparation method thereof |
| CN102349861B (en) * | 2011-10-13 | 2013-03-27 | 四川大学 | Phenolic acid modified collagen mask and preparation method thereof |
| CN102580139A (en) * | 2012-03-27 | 2012-07-18 | 黑龙江省华信药业有限公司 | Collagen hyaluronic acid dressing |
| CN102895164A (en) * | 2012-09-25 | 2013-01-30 | 石磊 | Moisture mask and preparation method thereof |
| CN103800224A (en) * | 2012-11-12 | 2014-05-21 | 陈英滨 | Cosmetic composition for skin care and beautifying method |
| CN103239372A (en) * | 2013-05-13 | 2013-08-14 | 南京理工大学 | Mild moisturizing mask liquid and preparation method thereof |
| CN103845228B (en) * | 2013-07-08 | 2016-04-20 | 重庆大学 | A kind of method preparing skin-friendly compound protein mask |
| CN103393568B (en) * | 2013-07-28 | 2015-09-30 | 娇时化妆品（杭州）有限公司 | A kind of whitening and spot eliminating cream |
| CN103432035B (en) * | 2013-08-23 | 2015-05-20 | 吴江华诚复合材料科技有限公司 | Preparation method of wash-free slow-release facial mask |
| CN103462829B (en) * | 2013-09-02 | 2015-04-15 | 广州市鼍龙生物技术开发有限公司 | Whitening and anti-wrinkle alligator oil skin-care product and preparation method thereof |
| CN104173212B (en) * | 2014-09-10 | 2016-08-17 | 百莲凯国际企业管理（北京）有限公司 | A kind of regeneration frost and preparation technology thereof |
| CN104323975A (en) * | 2014-11-03 | 2015-02-04 | 杨磊 | Nano-collagen moistening skin-care facial mask |
| CN105055202A (en) * | 2015-07-22 | 2015-11-18 | 西安米丽生物科技有限公司 | Facial mask with acne treating function and preparation method of facial mask |
| CN105250213B (en) * | 2015-11-06 | 2017-12-08 | 方祥铭 | A kind of marine alga polysaccharides facial mask and preparation method thereof |
| CN105816442A (en) * | 2016-01-05 | 2016-08-03 | 中国人民解放军第二军医大学 | 5-fluorouracil nanoparticle transdermal drug delivery electret preparation for treating hypertrophic scars based on action of electric field |
| CN105560081B (en) * | 2016-03-10 | 2018-04-20 | 东华大学 | A kind of preparation method of the moisture saver mask of chitosan-containing/collagen microballoon |
| CN105769706A (en) * | 2016-04-22 | 2016-07-20 | 齐齐哈尔市碾子山区麦饭石研究所 | Antibacterial and anti-inflammation paste medical stone facial mask and preparation method thereof |
| CN105902470A (en) * | 2016-06-02 | 2016-08-31 | 雷婷婷 | Mask paste for adjusting microcirculation of faces |
| CN105919830B (en) * | 2016-07-05 | 2018-12-18 | 湖南御家化妆品制造有限公司 | chitosan facial mask and preparation method thereof |
| CN106074460A (en) * | 2016-07-12 | 2016-11-09 | 中国人民解放军第二军医大学 | A kind of electret and the Percutaneously administrable preparation of 5 fluorouracil associating Inhibiting proliferation cicatrix growth |
| CN107260576B (en) * | 2017-05-16 | 2021-05-07 | 杭州千岛湖赋溪实业有限公司 | Facial mask gel containing dendrobium officinale polysaccharide and preparation method thereof |
| CN107374983A (en) * | 2017-07-05 | 2017-11-24 | 北京化工大学 | A kind of composite fibre facial mask rich in collagen and preparation method thereof |
| CN108498370B (en) * | 2018-05-21 | 2020-08-14 | 北京化工大学 | Rutin-containing multifunctional facial mask and preparation method thereof |
| CN108606933A (en) * | 2018-06-05 | 2018-10-02 | 深圳市旷逸生物科技有限公司 | A kind of Essence containing stem cell factor |
| CN110755296A (en) * | 2019-11-21 | 2020-02-07 | 广州元美盛化妆品有限公司 | Preservative-free facial moisturizing composition and preparation method thereof |
| CN110721132A (en) * | 2019-11-25 | 2020-01-24 | 广州元美盛化妆品有限公司 | Emollient and preparation method thereof |
| CN113143810A (en) * | 2020-09-24 | 2021-07-23 | 福建拓烯新材料科技有限公司 | Preparation method of soluble mulberry leaf spot-fading mask |
| CN112169008A (en) * | 2020-09-29 | 2021-01-05 | 代晓娟 | Preparation method of medical dressing based on human collagen |
| CN113307860A (en) * | 2021-06-11 | 2021-08-27 | 四川大学 | Method for extracting keratin from cow hair recovered from tanning based on biological enzymolysis |
| CN114903821A (en) * | 2021-07-08 | 2022-08-16 | 包计贤 | A facial mask rich in natural medicine and its preparation method |
| CN117860641B (en) * | 2024-03-12 | 2024-05-17 | 山东赫柏芳香生物科技有限公司 | Production process of moisturizing skin-care emulsion cosmetics |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1961960A (en) * | 2006-11-17 | 2007-05-16 | 桂林工学院 | Method for preparing magnetic macromolecular microsphere of crosslinking dialdehyde starch |
| CN101250827A (en) * | 2008-02-02 | 2008-08-27 | 四川大学 | Preparation of dialdehyde carboxymethyl cellulose and method for testing aldehyde group content |
-
2011
- 2011-03-31 CN CN2011100790139A patent/CN102138870B/en active Active
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1961960A (en) * | 2006-11-17 | 2007-05-16 | 桂林工学院 | Method for preparing magnetic macromolecular microsphere of crosslinking dialdehyde starch |
| CN101250827A (en) * | 2008-02-02 | 2008-08-27 | 四川大学 | Preparation of dialdehyde carboxymethyl cellulose and method for testing aldehyde group content |
Also Published As
| Publication number | Publication date |
|---|---|
| CN102138870A (en) | 2011-08-03 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN102138870B (en) | Collagen facial mask and preparation method thereof | |
| CN101889958B (en) | Freeze-dried composition | |
| CN100577136C (en) | Hydrous gel and production process and use of the hydrous gel | |
| CN103536452B (en) | Active collagen-beta-cyclodextrin facial mask and preparation method thereof | |
| CN103622864A (en) | Multifunctional aloe gel and preparation method thereof | |
| CN108969435A (en) | Reparation nourishing pack and its preparation and application containing fullerene | |
| CN1985791B (en) | Preparing process of skin care silk protein gel cream | |
| CN103505403B (en) | Epidermal growth factor composite liposome body and its preparation method and application | |
| CN102704319B (en) | The manufacture method of face paper and beauty and skin care paper film and facial mask | |
| CN102988262B (en) | Bee venom composition with acne removing function | |
| CN105147556A (en) | Stromal cell activation factor essence | |
| CN102380123B (en) | Collagen membrane medical dressing and preparation method thereof | |
| CN105310893A (en) | Condensate water mask and production method thereof | |
| CN104173232A (en) | Method for preparing beautifying fluid capable of promoting skin resistance and repairing small-invasive skin | |
| CN106317923A (en) | Manufacturing method of green and environmentally friendly tableware | |
| CN103212108B (en) | Collagen wound healing film and preparation method thereof | |
| CN107362108A (en) | A kind of Golden flower facial mask and preparation method thereof | |
| CN1682690A (en) | Bathing liquid composition and its preparing method | |
| CN106109264A (en) | A kind of facial treatment mask with anti-bacteria wet keeping function and preparation method thereof | |
| CN103705431B (en) | A kind of fish source collagen antioxidant peptide beauty mask and preparation method thereof | |
| CN105232426A (en) | Beautifying composition capable of tendering skin rapidly and application of beautifying composition | |
| CN103479567A (en) | Epidermal growth factor complex lipidosome, and preparation method and application of lipidosome | |
| CN103830119A (en) | Preparation method of toning lotion taking natural sericin as matrix | |
| CN104546514B (en) | A kind of hydrogel microcapsule type hair-care essence | |
| CN107951806A (en) | A kind of gentle more effect aloe skin care item and its preparation process |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| ASS | Succession or assignment of patent right |
Owner name: WUXI BIOT BIOLOGY TECHNOLOGY CO., LTD. Free format text: FORMER OWNER: SICHUAN UNIVERSITY Effective date: 20130327 |
|
| C41 | Transfer of patent application or patent right or utility model | ||
| COR | Change of bibliographic data |
Free format text: CORRECT: ADDRESS; FROM: 610207 CHENGDU, SICHUAN PROVINCE TO: 214092 WUXI, JIANGSU PROVINCE |
|
| TR01 | Transfer of patent right |
Effective date of registration: 20130327 Address after: 214092, Mashan biological pharmaceutical industry park (Ziyun Road), Binhu District, Jiangsu, Wuxi Province Patentee after: Wuxi Biot Bio-technology Co., Ltd. Address before: Shuangliu County Sichuan Road Chengdu City, Sichuan province 610207 2 No. 2 Patentee before: Sichuan University |
|
| C56 | Change in the name or address of the patentee | ||
| CP03 | Change of name, title or address |
Address after: 214000, Jiangsu, Wuxi province Mashan biological medicine industry park (business place, Wuxi, Binhu District, Mashan, Mei Liang Road, No. 132) Patentee after: Wuxi Betty biological engineering Limited by Share Ltd Address before: 214092, Mashan biological pharmaceutical industry park (Ziyun Road), Binhu District, Jiangsu, Wuxi Province Patentee before: Wuxi Biot Bio-technology Co., Ltd. |