CN102078562B - Chinese medicinal oral liquid for treating children metabolic syndrome and preparation method thereof - Google Patents
Chinese medicinal oral liquid for treating children metabolic syndrome and preparation method thereof Download PDFInfo
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- CN102078562B CN102078562B CN2009103105269A CN200910310526A CN102078562B CN 102078562 B CN102078562 B CN 102078562B CN 2009103105269 A CN2009103105269 A CN 2009103105269A CN 200910310526 A CN200910310526 A CN 200910310526A CN 102078562 B CN102078562 B CN 102078562B
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Abstract
The invention relates to a Chinese medicinal compound preparation, in particular to Chinese medicinal oral liquid for treating a children metabolic syndrome and a preparation method thereof. The Chinese medicinal oral liquid is characterized by being prepared from the following components: 1.0 part of root of red-rooted salvia, 0.5 to 1.0 part of curcuma aromatica, 1.0 to 2.0 parts of hawthorn fruit, 1.5 to 2.0 parts of coix seed, 0.5 to 1.0 part of rhubarb, 1.0 part of astragalus and 1.0 part of fragrant solomonseal rhizome. The preparation method comprises the following steps of: weighing medicinal materials according to the proportion of a formula; decocting the Chinese medicinal herbs and water in a ratio of 1:10 for 1.5 to 2.5 hours; filtering the obtained decoction to obtain filter liquor; standing the filter liquor, and taking supernate; and preparing the Chinese medicinal compound preparation according to 100 percent the medicinal concentration, namely a ratio of 1 gram of crude medicines to 1 milliliter of preparation, and bottling. The Chinese medicinal oral liquid has the advantages of low cost, good effect, obvious curative effect, no toxic or side effect and the like and is easy to prepare.
Description
Technical field:
The present invention relates to compound Chinese medicinal preparation, be specifically related to Chinese medicine oral liquid of a kind of child's of treatment metabolic syndrome and preparation method thereof.
Background technology:
Clinical alleged child's metabolic syndrome is meant that the child suffers from obesity and clinical syndromes such as impaired or type 2 diabetes mellitus, disorders of lipid metabolism, hypertension with carbohydrate metabolism simultaneously, it is intravital extensive metabolism of a kind of child of occurring in and dysfunction illness, has a strong impact on the healthy of child.Traditional treatment means blood lipid regulation often commonly used, hypoglycemic Western medicine, these medicines also are not suitable for child's use.Along with increasing gradually of fat infant, the control of child's metabolic syndrome has become demands the practical problem probed into both at home and abroad urgently.
Summary of the invention:
The present invention overcomes the deficiency that exists in the existing treatment means, propose a kind of cost low, effective, can effectively improve the blood pressure and blood lipoid metabolism, enhancing human body immunity, Chinese medicine oral liquid of the treatment child metabolic syndrome that has no side effect and preparation method thereof.
A kind of Chinese medicine oral liquid for the treatment of child's metabolic syndrome is characterized in that it being to be made by a certain percentage by Radix Salviae Miltiorrhizae, Radix Curcumae, Fructus Crataegi, Semen Coicis, Radix Et Rhizoma Rhei, the Radix Astragali, Rhizoma Polygonati Odorati.
The ratio of each component is described in the present invention: 1.0 parts of Radix Salviae Miltiorrhizaes, Radix Curcumae 0.5-1.0 part, Fructus Crataegi 1.0-2.0 part, Semen Coicis 1.5-2.0 part, Radix Et Rhizoma Rhei 0.5-1.0 part, 1.0 parts of the Radixs Astragali, 1.0 parts of Rhizoma Polygonati Odorati.
A kind of preparation method for the treatment of the Chinese medicine oral liquid of child's metabolic syndrome is characterized in that comprising the steps:
Steps A: take by weighing medical material by prescription proportion,
Step B: decocted 1.5-2.5 hour in 1: 10 ratio of total amount with water getting the Chinese herbal medicine of respectively distinguishing the flavor of in the steps A,
Step C: gained decoction among the step B is filtered, get filtrate,
Step D: filtrate being left standstill, got supernatant, is 100% by drug level, and promptly every milliliter of ratio that contains 1 gram crude drug is made compound Chinese medicinal preparation,
Step e: bottle by every bottle of 200 milliliters of specifications.
It is many by due to phlegm accumulating with stagnant blood, the deficiency of both QI and YIN to the present invention is directed to child's metabolic syndrome, by utilizing the Radix Salviae Miltiorrhizae blood circulation promoting and blood stasis dispelling, and the hawthorn digesting intestinal stasis relieving, Radix Astragali QI invigorating, the character of Rhizoma Polygonati Odorati YIN nourishing and the production of body fluid promoting is invigorated blood circulation to reduce phlegm and supplementing QI and nourishing YIN is main method of treatment.Modern pharmacology also confirms, said medicine has blood pressure lowering, blood viscosity lowering respectively, cholesterol reducing, enhancing human body immunity and helping digestion, effects such as blood sugar lowering, the present invention have low, the easy making of cost, effective, evident in efficacy, remarkable advantage such as have no side effect.
The specific embodiment:
A kind of Chinese medicine oral liquid for the treatment of child's metabolic syndrome is characterized in that it being to be made by a certain percentage by Radix Salviae Miltiorrhizae, Radix Curcumae, Fructus Crataegi, Semen Coicis, Radix Et Rhizoma Rhei, the Radix Astragali, Rhizoma Polygonati Odorati.
The ratio of each component is described in the present invention: 1.0 parts of Radix Salviae Miltiorrhizaes, Radix Curcumae 0.5-1.0 part, Fructus Crataegi 1.0-2.0 part, Semen Coicis 1.5-2.0 part, Radix Et Rhizoma Rhei 0.5-1.0 part, 1.0 parts of the Radixs Astragali, 1.0 parts of Rhizoma Polygonati Odorati.
A kind of preparation method for the treatment of the Chinese medicine oral liquid of child's metabolic syndrome is characterized in that comprising the steps:
Steps A: take by weighing medical material by prescription proportion,
Step B: decocted 1.5-2.5 hour in 1: 10 ratio of total amount with water getting the Chinese herbal medicine of respectively distinguishing the flavor of in the steps A,
Step C: gained decoction among the step B is filtered, get filtrate,
Step D: filtrate being left standstill, got supernatant, is 100% by drug level, and promptly every milliliter of ratio that contains 1 gram crude drug is made compound Chinese medicinal preparation,
Step e: bottle by every bottle of 200 milliliters of specifications.
Animal toxicology test: in acute toxicity test of the present invention, when giving the disposable filling stomach of rat with clinical identical route of administration, fail to obtain fatal dose of the present invention, through Cmax, maximum volume, irritate stomach three times on the one, the maximum tolerated dose multiple of obtaining rat is 220.4 times of clinical usual amounts, proves that oral administration safety of the present invention is high.
Treat by the infant of 114 examples being suffered from child's metabolic syndrome clinically, the each 10-15ml of 6-9 year child wherein, the each 15-20ml of child more than 9 years old, three times on the one, oral medication three months was a course of treatment.The result shows: child's Body Mass Index, fasting glucose, 2 hours after the meal indexs such as blood glucose, free serum fatty acid, triglyceride and c reactive protein all have clear improvement before the treatment, and compare with above-mentioned each index of 93 routine matched group infants in the same period, the difference significance, not seeing in the treatment has untoward reaction to take place.
It is many by phlegm accumulating with stagnant blood to the present invention is directed to child's metabolic syndrome, due to the deficiency of both QI and YIN, by utilizing Radix Salviae Miltiorrhizae and Radix Curcumae blood circulation promoting and blood stasis dispelling, the hawthorn digesting intestinal stasis relieving, the Semen Coicis promoting diuresis with drugs of tasteless flavour, Radix Et Rhizoma Rhei is broken to become silted up, Radix Astragali QI invigorating, the character of Rhizoma Polygonati Odorati YIN nourishing and the production of body fluid promoting, invigorate blood circulation to reduce phlegm and supplementing QI and nourishing YIN is main method of treatment, modern pharmacology confirms that also said medicine has blood pressure lowering respectively, blood viscosity lowering, cholesterol reducing, it is low that enhancing human body immunity and helping digestion, effects such as blood sugar lowering, the present invention have a cost, easily make, effective, evident in efficacy, remarkable advantage such as have no side effect.
Claims (1)
1.
A kind of Chinese medicine oral liquid for the treatment of child's metabolic syndrome, it is characterized in that it being to make in proportion by Radix Salviae Miltiorrhizae, Radix Curcumae, Fructus Crataegi, Semen Coicis, Radix Et Rhizoma Rhei, the Radix Astragali, Rhizoma Polygonati Odorati, the weight proportion of each component is: 1.0 parts of Radix Salviae Miltiorrhizaes, Radix Curcumae 0.5-1.0 part, Fructus Crataegi 1.0-2.0 part, Semen Coicis 1.5-2.0 part, Radix Et Rhizoma Rhei 0.5-1.0 part, 1.0 parts of the Radixs Astragali, 1.0 parts of Rhizoma Polygonati Odorati
2. a preparation method for the treatment of the Chinese medicine oral liquid of child's metabolic syndrome is characterized in that comprising the steps:
Steps A: be by weight ratio: 1.0 parts of Radix Salviae Miltiorrhizaes, Radix Curcumae 0.5-1.0 part, Fructus Crataegi 1.0-2.0 part, Semen Coicis 1.5-2.0 part, Radix Et Rhizoma Rhei 0.5-1.0 part, 1.0 parts of the Radixs Astragali, Rhizoma Polygonati Odorati takes by weighing medical material for 1.0 parts,
Step B: decocted 1.5-2.5 hour with the ratio of water getting the Chinese herbal medicine of respectively distinguishing the flavor of in the steps A in total amount 1:10,
Step C: gained decoction among the step B is filtered, get filtrate,
Step D: filtrate being left standstill, got supernatant, is 100% by drug level, and promptly every milliliter of ratio that contains 1 gram crude drug is made compound Chinese medicinal preparation,
Step e: bottle by every bottle of 200 milliliters of specifications.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2009103105269A CN102078562B (en) | 2009-11-27 | 2009-11-27 | Chinese medicinal oral liquid for treating children metabolic syndrome and preparation method thereof |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2009103105269A CN102078562B (en) | 2009-11-27 | 2009-11-27 | Chinese medicinal oral liquid for treating children metabolic syndrome and preparation method thereof |
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| Publication Number | Publication Date |
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| CN102078562A CN102078562A (en) | 2011-06-01 |
| CN102078562B true CN102078562B (en) | 2011-12-21 |
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| CN2009103105269A Expired - Fee Related CN102078562B (en) | 2009-11-27 | 2009-11-27 | Chinese medicinal oral liquid for treating children metabolic syndrome and preparation method thereof |
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Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN102579713B (en) * | 2012-03-23 | 2013-12-04 | 常熟市虞山绿茶有限公司 | Traditional Chinese medicine for treating children obesity and preparation method |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1720957A (en) * | 2004-12-23 | 2006-01-18 | 季友林 | Blood fat regulating Chinese medicinal composition, its preparation and using method |
| CN1806845A (en) * | 2005-01-19 | 2006-07-26 | 侯凤祥 | Medicinal composition, its preparation process and quality control method |
| CN101491595B (en) * | 2007-01-12 | 2011-11-30 | 福建中医学院 | Medicine of effective fractions of compounded prescription of Huomai Tiaozhi capsule and preparation technology thereof |
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2009
- 2009-11-27 CN CN2009103105269A patent/CN102078562B/en not_active Expired - Fee Related
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1720957A (en) * | 2004-12-23 | 2006-01-18 | 季友林 | Blood fat regulating Chinese medicinal composition, its preparation and using method |
| CN1806845A (en) * | 2005-01-19 | 2006-07-26 | 侯凤祥 | Medicinal composition, its preparation process and quality control method |
| CN101491595B (en) * | 2007-01-12 | 2011-11-30 | 福建中医学院 | Medicine of effective fractions of compounded prescription of Huomai Tiaozhi capsule and preparation technology thereof |
Non-Patent Citations (2)
| Title |
|---|
| 刘雁等.中医药治疗高脂血症的临床研究进展.《菏泽医学专科学校学报》.2005,(第02期), * |
| 王建清等.代谢综合征的中医药治疗概况.《新疆中医药》.2006,(第04期), * |
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| CN102078562A (en) | 2011-06-01 |
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Granted publication date: 20111221 Termination date: 20121127 |