CN102065865B - 多发性骨髓瘤治疗 - Google Patents
多发性骨髓瘤治疗 Download PDFInfo
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- CN102065865B CN102065865B CN2009801229778A CN200980122977A CN102065865B CN 102065865 B CN102065865 B CN 102065865B CN 2009801229778 A CN2009801229778 A CN 2009801229778A CN 200980122977 A CN200980122977 A CN 200980122977A CN 102065865 B CN102065865 B CN 102065865B
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- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/4995—Pyrazines or piperazines forming part of bridged ring systems
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- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
- A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
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- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
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- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
- A61K31/454—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. pimozide, domperidone
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- A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
- A61K31/573—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone substituted in position 21, e.g. cortisone, dexamethasone, prednisone or aldosterone
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- A61K31/7034—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin
- A61K31/704—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin attached to a condensed carbocyclic ring system, e.g. sennosides, thiocolchicosides, escin, daunorubicin
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- Inorganic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
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- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
Description
Claims (8)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
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EP08380154 | 2008-05-16 | ||
EP08380154.8 | 2008-05-16 | ||
PCT/EP2009/055978 WO2009138509A1 (en) | 2008-05-16 | 2009-05-18 | Multiple myeloma treatments |
Publications (2)
Publication Number | Publication Date |
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CN102065865A CN102065865A (zh) | 2011-05-18 |
CN102065865B true CN102065865B (zh) | 2013-03-20 |
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CN2009801229778A Expired - Fee Related CN102065865B (zh) | 2008-05-16 | 2009-05-18 | 多发性骨髓瘤治疗 |
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US (1) | US8435992B2 (zh) |
EP (1) | EP2303274A1 (zh) |
JP (1) | JP2011520846A (zh) |
KR (1) | KR20110028454A (zh) |
CN (1) | CN102065865B (zh) |
AU (1) | AU2009248039B2 (zh) |
CA (1) | CA2724206A1 (zh) |
IL (1) | IL209360A (zh) |
MX (1) | MX2010012358A (zh) |
NZ (1) | NZ589270A (zh) |
RU (1) | RU2519750C2 (zh) |
WO (1) | WO2009138509A1 (zh) |
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Publication number | Priority date | Publication date | Assignee | Title |
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US7919493B2 (en) | 2000-04-12 | 2011-04-05 | Pharma Mar, S.A. | Anititumoral ecteinascidin derivatives |
MXPA02011319A (es) | 2000-05-15 | 2003-06-06 | Pharma Mar Sa | Analogos antitumorales de ecteinascidina 743. |
GB0117402D0 (en) | 2001-07-17 | 2001-09-05 | Pharma Mar Sa | New antitumoral derivatives of et-743 |
GB0202544D0 (en) | 2002-02-04 | 2002-03-20 | Pharma Mar Sa | The synthesis of naturally occuring ecteinascidins and related compounds |
JP2011520921A (ja) * | 2008-05-16 | 2011-07-21 | ファルマ・マール・ソシエダード・アノニマ | 抗腫瘍アルカロイドとの併用療法 |
WO2011048210A1 (en) | 2009-10-22 | 2011-04-28 | Pharma Mar, S.A. | PDGFR-α AS RESPONSE MARKER FOR PM00104 TREATMENT |
KR101471273B1 (ko) * | 2013-01-29 | 2014-12-11 | 인제대학교 산학협력단 | Sod2를 포함하는 보르테조밉 내성 진단용 바이오 마커 조성물 및 이를 이용한 진단 키트 |
KR101718800B1 (ko) | 2015-01-21 | 2017-03-24 | 주식회사 디알나노 | 약물 및 siRNA의 공동―운반용 나노복합체 및 이의 용도 |
JOP20190254A1 (ar) | 2017-04-27 | 2019-10-27 | Pharma Mar Sa | مركبات مضادة للأورام |
US10537585B2 (en) | 2017-12-18 | 2020-01-21 | Dexcel Pharma Technologies Ltd. | Compositions comprising dexamethasone |
Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
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CN1211386A (zh) * | 1997-09-16 | 1999-03-24 | 林禾杰 | 对虾高产养殖新方法 |
WO2007052076A2 (en) * | 2005-10-31 | 2007-05-10 | Pharma Mar, S.A. | Formulations comprising jorumycin-, reni eramycin-, safracin- or saframycin-related compounds for treating proliferative diseases |
Family Cites Families (8)
Publication number | Priority date | Publication date | Assignee | Title |
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US6124292A (en) * | 1998-09-30 | 2000-09-26 | President And Fellows Of Harvard College | Synthetic analogs of ecteinascidin-743 |
MY130271A (en) * | 1999-05-14 | 2007-06-29 | Pharma Mar Sa | Hemisynthetic method and new compounds |
US6569859B1 (en) * | 2000-02-22 | 2003-05-27 | President And Fellows Of Harvard College | Synthetic analogs of ecteinascidin-743 |
MXPA02011319A (es) * | 2000-05-15 | 2003-06-06 | Pharma Mar Sa | Analogos antitumorales de ecteinascidina 743. |
GB0229793D0 (en) * | 2002-12-20 | 2003-01-29 | Pharma Mar Sa | The gene cluster involved in safracin biosynthesis and its uses for genetic engineering |
DK1603584T3 (da) * | 2003-03-12 | 2009-01-05 | Dana Farber Cancer Inst Inc | Aplidine til behandling af multipelt myelom |
TW200801513A (en) | 2006-06-29 | 2008-01-01 | Fermiscan Australia Pty Ltd | Improved process |
GB0708691D0 (en) * | 2007-05-04 | 2007-06-13 | Pharma Mar Sa | Anticancer treatments a |
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2009
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- 2009-05-18 CA CA2724206A patent/CA2724206A1/en not_active Abandoned
- 2009-05-18 NZ NZ589270A patent/NZ589270A/en not_active IP Right Cessation
- 2009-05-18 AU AU2009248039A patent/AU2009248039B2/en not_active Ceased
- 2009-05-18 US US12/992,754 patent/US8435992B2/en not_active Expired - Fee Related
- 2009-05-18 MX MX2010012358A patent/MX2010012358A/es active IP Right Grant
- 2009-05-18 EP EP09745841A patent/EP2303274A1/en not_active Withdrawn
- 2009-05-18 JP JP2011508943A patent/JP2011520846A/ja active Pending
- 2009-05-18 WO PCT/EP2009/055978 patent/WO2009138509A1/en active Application Filing
- 2009-05-18 RU RU2010151660/14A patent/RU2519750C2/ru not_active IP Right Cessation
- 2009-05-18 CN CN2009801229778A patent/CN102065865B/zh not_active Expired - Fee Related
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2010
- 2010-11-16 IL IL209360A patent/IL209360A/en not_active IP Right Cessation
Patent Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN1211386A (zh) * | 1997-09-16 | 1999-03-24 | 林禾杰 | 对虾高产养殖新方法 |
WO2007052076A2 (en) * | 2005-10-31 | 2007-05-10 | Pharma Mar, S.A. | Formulations comprising jorumycin-, reni eramycin-, safracin- or saframycin-related compounds for treating proliferative diseases |
Also Published As
Publication number | Publication date |
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RU2519750C2 (ru) | 2014-06-20 |
NZ589270A (en) | 2011-12-22 |
CN102065865A (zh) | 2011-05-18 |
RU2010151660A (ru) | 2012-06-27 |
EP2303274A1 (en) | 2011-04-06 |
CA2724206A1 (en) | 2009-11-19 |
IL209360A0 (en) | 2011-01-31 |
MX2010012358A (es) | 2011-01-25 |
KR20110028454A (ko) | 2011-03-18 |
US8435992B2 (en) | 2013-05-07 |
IL209360A (en) | 2015-10-29 |
AU2009248039B2 (en) | 2014-07-31 |
US20110076343A1 (en) | 2011-03-31 |
WO2009138509A1 (en) | 2009-11-19 |
JP2011520846A (ja) | 2011-07-21 |
AU2009248039A1 (en) | 2009-11-19 |
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