CN102008551A - Medicinal composition for treating pains of necks, shoulders and arms and preparation method and application thereof - Google Patents

Medicinal composition for treating pains of necks, shoulders and arms and preparation method and application thereof Download PDF

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CN102008551A
CN102008551A CN2010105657967A CN201010565796A CN102008551A CN 102008551 A CN102008551 A CN 102008551A CN 2010105657967 A CN2010105657967 A CN 2010105657967A CN 201010565796 A CN201010565796 A CN 201010565796A CN 102008551 A CN102008551 A CN 102008551A
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radix
herba
angelicae sinensis
hedysari
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CN102008551B (en
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潘畅
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Abstract

The invention belongs to the field of medicines and solves the technical problems of a medicinal composition for treating pains of necks, shoulders and arms and a preparation method and application thereof. The medicinal composition comprises active ingredients which are prepared from the following raw material medicaments in part by weight: 1 to 3 parts of vine root, 5 to 9 parts of yellowmouth dutchmanspipe root, 2 to 4 parts of snow lotus, 2 to 4 parts of szechuan lovage rhizome, 5 to 7 parts of astragalus or 3 to 5 parts of radix hedysari, and 2 to 5 parts of Chinese angelica. The medicinal composition can obviously relieve pains and ease pains and has obvious treatment effects on pain symptoms caused by cervical spondylosis, scapulohumeral periarthritis, stiff neck, cervical muscle strain and the like.

Description

A kind of pharmaceutical composition for the treatment of neck, shoulder, arm pain and its production and use
Technical field
The invention belongs to field of medicaments, be specifically related to a kind of pharmaceutical composition for the treatment of neck, shoulder, arm pain and its production and use.
Background technology
The pain a kind of offending reaction that to be body produce damaged tissue or potential damage is a kind of complex physical mental activity, is one of modal symptom clinically.
The main disease of diseases such as cervical spondylosis, scapulohumeral periarthritis, stiff neck, cervical muscle strain is a pain, caused as the cervical spondylosis of medically being said because of degeneration of cervical intervertebral disc, hyperosteogeny of cervical vertebra, with neck and shoulder pain, emit to headrest portion or upper limb, two lower limb spasm appear in very heavy person, difficulty in walking is so that quadriplegia is the syndrome of main performance.Pain can cause significant impact to patient's life, work and study, but lack the medicine that the pain of cervical spondylosis, scapulohumeral periarthritis, stiff neck, cervical muscle strain is had remarkable specific aim analgesia effect at present always, based on above-mentioned present situation, the invention human desires provides a kind of brand-new medicine to be used for the treatment of or to alleviate the pain symptom of diseases such as cervical spondylosis, stiff neck, cervical muscle strain, cervical muscle strain.
Summary of the invention
Technical problem solved by the invention provides a kind of pharmaceutical composition for the treatment of neck, shoulder, arm pain.
Active ingredient in pharmaceutical of the present invention is to be prepared from by following materials of weight proportions medicine:
Radix Puerariae 1-3 part, Radix Stephaniae Tetrandrae 5-9 part, Herba Saussureae Involueratae 2-4 part, Rhizoma Chuanxiong 2-4 part, Radix Astragali 5-7 part or Radix Hedysari 3-5 part, Radix Angelicae Sinensis 2-5 part;
Further preferred: 2 parts of Radix Puerariaes, 7 parts of Radixs Stephaniae Tetrandrae, 2 parts of Herba Saussureae Involueratae, 2 parts of Rhizoma Chuanxiongs, 5 parts of the Radixs Astragali or 3 parts of Radix Hedysari, 3 parts of Radix Angelicae Sinensis.
But pharmaceutical composition spasmolysis and analgesia of the present invention is alleviated neck shoulder arm pain, and especially the pain to initiations such as cervical spondylosis, scapulohumeral periarthritis, stiff neck, cervical muscle strains has tangible alleviation, therapeutic effect.Radix Puerariae, Radix Stephaniae Tetrandrae, Herba Saussureae Involueratae, Rhizoma Chuanxiong, the Radix Astragali or Radix Hedysari, Radix Angelicae Sinensis have constituted of the present invention square substantially.
Sum up through prolonged application, the invention provides can be respectively at the pharmaceutical composition of arthralgia due to cold disease and pyretic arthralgia disease.
If cervical spondylosis patient's arthralgia due to cold disease, its clinical manifestation is: neck shoulder arm contracture cold type of pain, and numbness, pain exaggerated by catching cold, tongue fur is white, greasy, tense pulse.Add Ramulus Cinnamomi and Pheretima on basic side's of the present invention basis, the effect of Pheretima tonneau meridians is obvious, but belongs to cold.Compatibility has the Ramulus Cinnamomi of promoting the flow of QI in the collateral by warming the meridian, restrains the cold fraud of Pheretima first, but QI and blood regulating second is especially obvious at the cold pain of upper limbs effect.The two compatibility is used, and with the cold and cool impairment of YIN of system Pheretima, warm dry of slow again Ramulus Cinnamomi exempted from the impairment of QI-blood.Active ingredient in pharmaceutical at arthralgia due to cold disease is to be prepared from by following materials of weight proportions medicine:
Radix Puerariae 1-3 part, Radix Stephaniae Tetrandrae 5-9 part, Herba Saussureae Involueratae 2-4 part, Rhizoma Chuanxiong 2-4 part, Radix Astragali 5-7 part or Radix Hedysari 3-5 part, Radix Angelicae Sinensis 2-5 part, Pheretima 5-7 part, Ramulus Cinnamomi 1-2 part;
Preferably: 2 parts of Radix Puerariaes, 7 parts of Radixs Stephaniae Tetrandrae, 2 parts of Herba Saussureae Involueratae, 2 parts of Rhizoma Chuanxiongs, 5 parts of the Radixs Astragali or 3 parts of Radix Hedysari, 3 parts of Radix Angelicae Sinensis, 5 parts of Pheretimas, 1 part of Ramulus Cinnamomi.
If cervical spondylosis patient's pyretic arthralgia disease, its clinical manifestation is: neck shoulder arm causalgia, the fiber crops of expanding are met burning pain and increase yellow fur, stringy and tense pulse.On basic side's of the present invention basis, add Ramulus Mori and Herba Lycopi, the Ramulus Mori of Herba Lycopi's activating blood and promoting diuresis 5 dispelling wind and removing obstruction in the collateral warm in nature, mutual-assistance mutual restraint between two drugs can improve the analgesia timeliness to upper limb pyretic arthralgia pain especially.Active ingredient in pharmaceutical at pyretic arthralgia disease is to be prepared from by following materials of weight proportions medicine:
Radix Puerariae 1-3 part, Radix Stephaniae Tetrandrae 5-9 part, Herba Saussureae Involueratae 2-4 part, Rhizoma Chuanxiong 2-4 part, Radix Astragali 5-7 part or Radix Hedysari 3-5 part, Radix Angelicae Sinensis 2-5 part, Herba Lycopi 3-5 part, Ramulus Mori 1-3 part;
Preferably: 2 parts of Radix Puerariaes, 7 parts of Radixs Stephaniae Tetrandrae, 2 parts of Herba Saussureae Involueratae, 2 parts of Rhizoma Chuanxiongs, 5 parts of the Radixs Astragali or 3 parts of Radix Hedysari, 3 parts of Radix Angelicae Sinensis, 4 parts of Herba Lycopi, 2 parts of Ramulus Moris.
In order to strengthen the effect of spasmolysis and analgesia, can also be in basis side of the present invention, and add the Radix Paeoniae Alba and Radix Glycyrrhizae on the basis at three prescriptions of arthralgia due to cold disease and pyretic arthralgia disease respectively, its composition is respectively:
Basic side adds the Radix Paeoniae Alba and Radix Glycyrrhizae is: Radix Puerariae 1-3 part, Radix Stephaniae Tetrandrae 5-9 part, Herba Saussureae Involueratae 2-4 part, Rhizoma Chuanxiong 2-4 part, Radix Astragali 5-7 part or Radix Hedysari 3-5 part, Radix Angelicae Sinensis 2-5 part, Radix Paeoniae Alba 5-7 part, Radix Glycyrrhizae 3-5 part; 2 parts of preferred Radix Puerariaes, 7 parts of Radixs Stephaniae Tetrandrae, 2 parts of Herba Saussureae Involueratae, 2 parts of Rhizoma Chuanxiongs, 5 parts of the Radixs Astragali or 3 parts of Radix Hedysari, 3 parts of Radix Angelicae Sinensis, 6 parts of the Radix Paeoniae Albas, 3 parts in Radix Glycyrrhizae.Or
Arthralgia due to cold disease side adds the Radix Paeoniae Alba and Radix Glycyrrhizae is: Radix Puerariae 1-3 part, Radix Stephaniae Tetrandrae 5-9 part, Herba Saussureae Involueratae 2-4 part, Rhizoma Chuanxiong 2-4 part, Radix Astragali 5-7 part or Radix Hedysari 3-5 part, Radix Angelicae Sinensis 2-5 part, Pheretima 5-7 part, Ramulus Cinnamomi 1-2 part, Radix Paeoniae Alba 5-7 part, Radix Glycyrrhizae 3-5 part; 2 parts of preferred Radix Puerariaes, 7 parts of Radixs Stephaniae Tetrandrae, 2 parts of Herba Saussureae Involueratae, 2 parts of Rhizoma Chuanxiongs, 5 parts of the Radixs Astragali or 3 parts of Radix Hedysari, 3 parts of Radix Angelicae Sinensis, 5 parts of Pheretimas, 1 part of Ramulus Cinnamomi, 6 parts of the Radix Paeoniae Albas, 3 parts in Radix Glycyrrhizae.Or
Pyretic arthralgia disease side adds the Radix Paeoniae Alba and Radix Glycyrrhizae is: Radix Puerariae 1-3 part, Radix Stephaniae Tetrandrae 5-9 part, Herba Saussureae Involueratae 2-4 part, Rhizoma Chuanxiong 2-4 part, Radix Astragali 5-7 part or Radix Hedysari 3-5 part, Radix Angelicae Sinensis 2-5 part, Herba Lycopi 3-5 part, Ramulus Mori 1-3 part, Radix Paeoniae Alba 5-7 part, Radix Glycyrrhizae 3-5 part; 2 parts of preferred Radix Puerariaes, 7 parts of Radixs Stephaniae Tetrandrae, 2 parts of Herba Saussureae Involueratae, 2 parts of Rhizoma Chuanxiongs, 5 parts of the Radixs Astragali or 3 parts of Radix Hedysari, 3 parts of Radix Angelicae Sinensis, 4 parts of Herba Lycopi, 2 parts of Ramulus Moris, 6 parts of the Radix Paeoniae Albas, 3 parts in Radix Glycyrrhizae.
Because the patient is difficult for dialectical when using, so the present invention also provides one to need not the prescription of distinguishing that cold syndrome, heat syndrome can be used, promptly add Herba Lycopi, Ramulus Mori, Ramulus Cinnamomi, Pheretima, the Radix Paeoniae Alba, Radix Glycyrrhizae, Rhizoma Corydalis, Herba Lycopodii on the basis of basic side, active ingredient in pharmaceutical is to be prepared from by following materials of weight proportions medicine:
Radix Puerariae 1-3 part, Radix Stephaniae Tetrandrae 5-9 part, Herba Saussureae Involueratae 2-4 part, Rhizoma Chuanxiong 2-4 part, Radix Astragali 5-7 part or Radix Hedysari 3-5 part, Radix Angelicae Sinensis 2-5 part, Herba Lycopi 3-5 part, Ramulus Mori 1-3 part, Ramulus Cinnamomi 1-2 part, Pheretima 5-7 part, Radix Paeoniae Alba 5-7 part, Radix Glycyrrhizae 3-5 part, Rhizoma Corydalis 3-5 part, Herba Lycopodii 3-5 part;
Preferably: 2 parts of Radix Puerariaes, 7 parts of Radixs Stephaniae Tetrandrae, 2 parts of Herba Saussureae Involueratae, 2 parts of Rhizoma Chuanxiongs, 5 parts of the Radixs Astragali or 3 parts of Radix Hedysari, 3 parts of Radix Angelicae Sinensis, 4 parts of Herba Lycopi, 2 parts of Ramulus Moris, 1 part of Ramulus Cinnamomi, 5 parts of Pheretimas, 6 parts of the Radix Paeoniae Albas, 3 parts in Radix Glycyrrhizae, 3 parts of Rhizoma Corydalis, 4 parts of Herba Lycopodiis.
One of the crude drug that aforementioned pharmaceutical compositions adopts Radix Hedysari can adopt Radix Hedysari Preparata, and the Radix Astragali can adopt Radix Astragali Preparata to replace, and can strengthen the effect of QI invigorating.
Pharmaceutical composition of the present invention is to adopt the above-mentioned raw materials medicine, adds the medicament that acceptable accessories is prepared from according to conventional method; Mainly based on oral formulations.At the application characteristic of medicine of the present invention, also provide this preparation of drug combination method.
Method one: each crude drug is ground into fine powder, makes capsule according to a conventional method.Encapsulated as fine powder being mixed the back, or fine powder granulation back is encapsulated.
Method two: each crude drug is ground into fine powder, makes pill according to a conventional method.
Method three: each crude drug is ground into fine powder, is pressed into tablet according to a conventional method.
Method four: each crude drug is ground into fine powder, mix powder.
Method five: with each raw material routinely the decocting mode boil.
Use said method and all can realize pain relieving analgesic purpose, but easy in response to the convenience of usefulness and preparation, the inventor is made into capsule more and uses.
To sum up, use pharmaceutical composition provided by the invention and all can realize the effect of pain relieving analgesic, especially the pain at initiations such as cervical spondylosis, scapulohumeral periarthritis, stiff neck, cervical muscle strains has clear and definite therapeutic effect, and stable curative effect is controlled.
The specific embodiment
Below by specific description of embodiments of the present invention the explanation but do not limit the present invention.
Pharmaceutical composition of the present invention square substantially: the crude drug weight proportion is Radix Puerariae 1-3 part, Radix Stephaniae Tetrandrae 5-9 part, Herba Saussureae Involueratae 2-4 part, Rhizoma Chuanxiong 2-4 part, Radix Astragali 5-7 part or Radix Hedysari 3-5 part, Radix Angelicae Sinensis 2-5 part.Crude drug floats in this amount ranges and all can realize analgesia, aim of alleviating pain.
Find that through inventor's long-term practice 2 parts of Radix Puerariaes, 7 parts of Radixs Stephaniae Tetrandrae, 2 parts of Herba Saussureae Involueratae, 2 parts of Rhizoma Chuanxiongs, 5 parts of the Radixs Astragali or 3 parts of Radix Hedysari, 3 parts of effects of Radix Angelicae Sinensis are clearer and more definite, more stable.
Further, in order to adapt to arthralgia due to cold disease and pyretic arthralgia disease, the present invention provides two to add flavor side again:
At arthralgia due to cold disease, increase Ramulus Cinnamomi and Pheretima, the crude drug weight proportion is Radix Puerariae 1-3 part, Radix Stephaniae Tetrandrae 5-9 part, Herba Saussureae Involueratae 2-4 part, Rhizoma Chuanxiong 2-4 part, Radix Astragali 5-7 part or Radix Hedysari 3-5 part, Radix Angelicae Sinensis 2-5 part, Pheretima 5-7 part, Ramulus Cinnamomi 1-2 part;
Preferably: 2 parts of Radix Puerariaes, 7 parts of Radixs Stephaniae Tetrandrae, 2 parts of Herba Saussureae Involueratae, 2 parts of Rhizoma Chuanxiongs, 5 parts of the Radixs Astragali or 3 parts of Radix Hedysari, 3 parts of Radix Angelicae Sinensis, 5 parts of Pheretimas, 1 part of Ramulus Cinnamomi.
At pyretic arthralgia disease, increase Ramulus Mori and Herba Lycopi, the crude drug weight proportion is Radix Puerariae 1-3 part, Radix Stephaniae Tetrandrae 5-9 part, Herba Saussureae Involueratae 2-4 part, Rhizoma Chuanxiong 2-4 part, Radix Astragali 5-7 part or Radix Hedysari 3-5 part, Radix Angelicae Sinensis 2-5 part, Herba Lycopi 3-5 part, Ramulus Mori 1-3 part;
Preferably: 2 parts of Radix Puerariaes, 7 parts of Radixs Stephaniae Tetrandrae, 2 parts of Herba Saussureae Involueratae, 2 parts of Rhizoma Chuanxiongs, 5 parts of the Radixs Astragali or 3 parts of Radix Hedysari, 3 parts of Radix Angelicae Sinensis, 4 parts of Herba Lycopi, 2 parts of Ramulus Moris.
And, on the basis of basic side and 2 improvement sides, added the Radix Paeoniae Alba and Radix Glycyrrhizae again in order to strengthen the effect of spasmolysis and analgesia.
Final inventor provides a kind of not only can but also can simplify the criterion of clinical diagnosis at the pharmaceutical composition of pyretic arthralgia disease at arthralgia due to cold disease, also reduced the difficulty that the patient selects medicine, promptly add Herba Lycopi, Ramulus Mori, Ramulus Cinnamomi, Pheretima, the Radix Paeoniae Alba, Radix Glycyrrhizae, Rhizoma Corydalis, Herba Lycopodii on the basis of basic side, its active component is to be prepared from by following materials of weight proportions medicine:
Radix Puerariae 1-3 part, Radix Stephaniae Tetrandrae 5-9 part, Herba Saussureae Involueratae 2-4 part, Rhizoma Chuanxiong 2-4 part, Radix Astragali 5-7 part or Radix Hedysari 3-5 part, Radix Angelicae Sinensis 2-5 part, Herba Lycopi 3-5 part, Ramulus Mori 1-3 part, Ramulus Cinnamomi 1-2 part, Pheretima 5-7 part, Radix Paeoniae Alba 5-7 part, Radix Glycyrrhizae 3-5 part, Rhizoma Corydalis 3-5 part, Herba Lycopodii 3-5 part;
Preferably: 2 parts of Radix Puerariaes, 7 parts of Radixs Stephaniae Tetrandrae, 2 parts of Herba Saussureae Involueratae, 2 parts of Rhizoma Chuanxiongs, 5 parts of the Radixs Astragali or 3 parts of Radix Hedysari, 3 parts of Radix Angelicae Sinensis, 4 parts of Herba Lycopi, 2 parts of Ramulus Moris, 1 part of Ramulus Cinnamomi, 5 parts of Pheretimas, 6 parts of the Radix Paeoniae Albas, 3 parts in Radix Glycyrrhizae, 3 parts of Rhizoma Corydalis, 4 parts of Herba Lycopodiis;
For the ease of using, can on the basis of crude drug, add acceptable accessories and make oral formulations commonly used.As powder, pill, tablet, capsule, water decoction.
The pain that pharmaceutical composition of the present invention causes at cervical spondylosis, stiff neck, cervical muscle strain etc., relieving pain, stable curative effect, controlled.
Below beneficial effect by clinical statistics proof pharmaceutical composition of the present invention.
It is clinical that the inventor adopts pharmaceutical composition of the present invention to be applied to, and specifically is to be made into capsule to use, and capsule preparation method thereof is as follows:
1, capsule A (square substantially): 2 parts of Radix Puerariaes, 7 parts of Radixs Stephaniae Tetrandrae, 2 parts of Herba Saussureae Involueratae, 2 parts of Rhizoma Chuanxiongs, 3 parts of Radix Hedysari, 3 parts of Radix Angelicae Sinensis.Pulverizing the back mixes encapsulated.Every capsules contains crude drug 0.4g.
2, capsule B (arthralgia due to cold disease side): 2 parts of Radix Puerariaes, 7 parts of Radixs Stephaniae Tetrandrae, 2 parts of Herba Saussureae Involueratae, 2 parts of Rhizoma Chuanxiongs, 3 parts of Radix Hedysari, 3 parts of Radix Angelicae Sinensis, 5 parts of Pheretimas, 1 part of Ramulus Cinnamomi.Pulverizing the back mixes encapsulated.Every capsules contains crude drug 0.4g.
3, capsule C (pyretic arthralgia disease side): 2 parts of Radix Puerariaes, 7 parts of Radixs Stephaniae Tetrandrae, 2 parts of Herba Saussureae Involueratae, 2 parts of Rhizoma Chuanxiongs, 3 parts of Radix Hedysari, 3 parts of Radix Angelicae Sinensis, 4 parts of Herba Lycopi, 2 parts of Ramulus Moris.Pulverizing the back mixes encapsulated.Every capsules contains crude drug 0.4g.
4, capsule D (square+Radix Paeoniae Alba+Radix Glycyrrhizae substantially): 2 parts of Radix Puerariaes, 7 parts of Radixs Stephaniae Tetrandrae, 2 parts of Herba Saussureae Involueratae, 2 parts of Rhizoma Chuanxiongs, 3 parts of Radix Hedysari, 3 parts of Radix Angelicae Sinensis, 6 parts of the Radix Paeoniae Albas, 3 parts in Radix Glycyrrhizae.Pulverizing the back mixes encapsulated.Every capsules contains crude drug 0.4g.
5, capsule E (the arthralgia due to cold disease side+Radix Paeoniae Alba+Radix Glycyrrhizae): 2 parts of Radix Puerariaes, 7 parts of Radixs Stephaniae Tetrandrae, 2 parts of Herba Saussureae Involueratae, 2 parts of Rhizoma Chuanxiongs, 3 parts of Radix Hedysari, 3 parts of Radix Angelicae Sinensis, 5 parts of Pheretimas, 1 part of Ramulus Cinnamomi, 6 parts of the Radix Paeoniae Albas, 3 parts in Radix Glycyrrhizae.Pulverizing the back mixes encapsulated.Every capsules contains crude drug 0.4g.
6, capsule F (the pyretic arthralgia disease side+Radix Paeoniae Alba+Radix Glycyrrhizae): 2 parts of Radix Puerariaes, 7 parts of Radixs Stephaniae Tetrandrae, 2 parts of Herba Saussureae Involueratae, 2 parts of Rhizoma Chuanxiongs, 3 parts of Radix Hedysari, 3 parts of Radix Angelicae Sinensis, 4 parts of Herba Lycopi, 2 parts of Ramulus Moris, 6 parts of the Radix Paeoniae Albas, 3 parts in Radix Glycyrrhizae.Pulverizing the back mixes encapsulated.Every capsules contains crude drug 0.4g.
7, capsule G (optimum side): 2 parts of Radix Puerariaes, 7 parts of Radixs Stephaniae Tetrandrae, 2 parts of Herba Saussureae Involueratae, 2 parts of Rhizoma Chuanxiongs, 5 parts of the Radixs Astragali or 3 parts of Radix Hedysari, 3 parts of Radix Angelicae Sinensis, 4 parts of Herba Lycopi, 2 parts of Ramulus Moris, 1 part of Ramulus Cinnamomi, 5 parts of Pheretimas, 6 parts of the Radix Paeoniae Albas, 3 parts in Radix Glycyrrhizae, 3 parts of Rhizoma Corydalis, 4 parts of Herba Lycopodiis.Pulverizing the back mixes encapsulated.Every capsules contains crude drug 0.4g.
Control drug: commercially available Radix Notoginseng Tabellae.
Oral powder pharmaceutical composition of the present invention and control drug are to impose corresponding medicine after dialectical to the patient at capsule B, C, E, F particularly.Medicine adult taking dose of the present invention is each 1.2g, 3 times on the one, be 20 days (except that stiff neck) course of treatment, for evaluating onset time, at the 10th day the patient is visited, understand the alleviation situation of its pain symptom, the analgesic effect statistical data sees Table 1-4: the pain relieving assessment method adopts range estimation analogy point system (VAS method).
Table 1 cervical spondylosis
Figure BDA0000035248300000051
Table 2 stiff neck
Figure BDA0000035248300000052
Table 3 scapulohumeral periarthritis
Figure BDA0000035248300000061
Table 4 cervical muscle strain
Figure BDA0000035248300000062
Pass through above-mentioned clinical statistics and can find out that pharmaceutical composition of the present invention total effective rate majority after a course of treatment can reach more than 90, especially at the cervical pain symptom significant curative effect is arranged, and a little less than the summary of the therapeutic effect of scapulohumeral periarthritis.The onset time of basic side is longer, but effective percentage can reach 75% at least after a course of treatment, and can reach 100% for commonly encountered diseases curative effects such as stiff necks.
Pharmaceutical composition of the present invention is year clinical large sample statistical observation surplus ten, last definite behind the screening prescription with Radix Puerariae, Radix Stephaniae Tetrandrae, Herba Saussureae Involueratae, Rhizoma Chuanxiong, the Radix Astragali or Radix Hedysari, Radix Angelicae Sinensis, the Herba Lycopi, Ramulus Mori, Ramulus Cinnamomi, Pheretima, the Radix Paeoniae Alba, Radix Glycyrrhizae, Rhizoma Corydalis, Herba Lycopodii is a crude drug, therapeutic effect the best, reduce the dialectical operation of clinical cold and heat, determine that its best proportion relation is: 2 parts of Radix Puerariaes, 7 parts of Radixs Stephaniae Tetrandrae, 2 parts of Herba Saussureae Involueratae, 2 parts of Rhizoma Chuanxiongs, 3 parts of 5 parts of the Radixs Astragali or Radix Hedysari, 3 parts of Radix Angelicae Sinensis, 4 parts of Herba Lycopi, 2 parts of Ramulus Moris, 1 part of Ramulus Cinnamomi, 5 parts of Pheretimas, 6 parts of the Radix Paeoniae Albas, 3 parts in Radix Glycyrrhizae, 3 parts of Rhizoma Corydalis, 4 parts of Herba Lycopodiis; Therapeutic effect is clear and definite, stable curative effect.Again because of Radix Hedysari invigorating the spleen and replenishing QI effect is better than the Radix Astragali, so the normal Radix Hedysari that adopts.

Claims (9)

1. pharmaceutical composition for the treatment of neck, shoulder, arm pain, it is characterized in that: active ingredient in pharmaceutical is to be prepared from by following materials of weight proportions medicine:
Radix Puerariae 1-3 part, Radix Stephaniae Tetrandrae 5-9 part, Herba Saussureae Involueratae 2-4 part, Rhizoma Chuanxiong 2-4 part, Radix Astragali 5-7 part or Radix Hedysari 3-5 part, Radix Angelicae Sinensis 2-5 part;
Preferably: 2 parts of Radix Puerariaes, 7 parts of Radixs Stephaniae Tetrandrae, 2 parts of Herba Saussureae Involueratae, 2 parts of Rhizoma Chuanxiongs, 5 parts of the Radixs Astragali or 3 parts of Radix Hedysari, 3 parts of Radix Angelicae Sinensis.
2. the pharmaceutical composition of treatment neck according to claim 1, shoulder, arm pain is characterized in that: it also contains Pheretima and Ramulus Cinnamomi, and active ingredient in pharmaceutical is to be prepared from by following materials of weight proportions medicine:
Radix Puerariae 1-3 part, Radix Stephaniae Tetrandrae 5-9 part, Herba Saussureae Involueratae 2-4 part, Rhizoma Chuanxiong 2-4 part, Radix Astragali 5-7 part or Radix Hedysari 3-5 part, Radix Angelicae Sinensis 2-5 part, Pheretima 5-7 part, Ramulus Cinnamomi 1-2 part;
Preferably: 2 parts of Radix Puerariaes, 7 parts of Radixs Stephaniae Tetrandrae, 2 parts of Herba Saussureae Involueratae, 2 parts of Rhizoma Chuanxiongs, 5 parts of the Radixs Astragali or 3 parts of Radix Hedysari, 3 parts of Radix Angelicae Sinensis, 5 parts of Pheretimas, 1 part of Ramulus Cinnamomi.
3. the pharmaceutical composition of treatment neck according to claim 1, shoulder, arm pain is characterized in that: it also contains Herba Lycopi and Ramulus Mori, and active ingredient in pharmaceutical is to be prepared from by following materials of weight proportions medicine:
Radix Puerariae 1-3 part, Radix Stephaniae Tetrandrae 5-9 part, Herba Saussureae Involueratae 2-4 part, Rhizoma Chuanxiong 2-4 part, Radix Astragali 5-7 part or Radix Hedysari 3-5 part, Radix Angelicae Sinensis 2-5 part, Herba Lycopi 3-5 part, Ramulus Mori 1-3 part;
Preferably: 2 parts of Radix Puerariaes, 7 parts of Radixs Stephaniae Tetrandrae, 2 parts of Herba Saussureae Involueratae, 2 parts of Rhizoma Chuanxiongs, 5 parts of the Radixs Astragali or 3 parts of Radix Hedysari, 3 parts of Radix Angelicae Sinensis, 4 parts of Herba Lycopi, 2 parts of Ramulus Moris.
4. according to the pharmaceutical composition of each described treatment neck of claim 1-3, shoulder, arm pain, it is characterized in that: it also contains Radix Paeoniae Alba 5-7 part, Radix Glycyrrhizae 3-5 part.
5. the pharmaceutical composition of treatment neck according to claim 1, shoulder, arm pain, it is characterized in that: it also contains Herba Lycopi, Ramulus Mori, Ramulus Cinnamomi, Pheretima, the Radix Paeoniae Alba, Radix Glycyrrhizae, Rhizoma Corydalis, Herba Lycopodii, and active ingredient in pharmaceutical is to be prepared from by following materials of weight proportions medicine:
Radix Puerariae 1-3 part, Radix Stephaniae Tetrandrae 5-9 part, Herba Saussureae Involueratae 2-4 part, Rhizoma Chuanxiong 2-4 part, Radix Astragali 5-7 part or Radix Hedysari 3-5 part, Radix Angelicae Sinensis 2-5 part, Herba Lycopi 3-5 part, Ramulus Mori 1-3 part, Ramulus Cinnamomi 1-2 part, Pheretima 5-7 part, Radix Paeoniae Alba 5-7 part, Radix Glycyrrhizae 3-5 part, Rhizoma Corydalis 3-5 part, Herba Lycopodii 3-5 part;
Preferably: 2 parts of Radix Puerariaes, 7 parts of Radixs Stephaniae Tetrandrae, 2 parts of Herba Saussureae Involueratae, 2 parts of Rhizoma Chuanxiongs, 5 parts of the Radixs Astragali or 3 parts of Radix Hedysari, 3 parts of Radix Angelicae Sinensis, 4 parts of Herba Lycopi, 2 parts of Ramulus Moris, 1 part of Ramulus Cinnamomi, 5 parts of Pheretimas, 6 parts of the Radix Paeoniae Albas, 3 parts in Radix Glycyrrhizae, 3 parts of Rhizoma Corydalis, 4 parts of Herba Lycopodiis;
6. according to the pharmaceutical composition of each described treatment neck of claim 1-5, shoulder, arm pain, it is characterized in that: described pharmaceutical composition is an oral formulations.
7. the preparation of drug combination method of each described treatment neck of claim 1-6, shoulder, arm pain is characterized in that: adopt the following steps preparation:
A, each crude drug is ground into fine powder, mixes getting final product; Or
B, fine powder is made pill according to a conventional method; Or
Fine powder is pressed into tablet according to a conventional method; Or
Make capsule according to a conventional method.
8. the preparation of drug combination method of each described treatment neck of claim 1-6, shoulder, arm pain is characterized in that: adopt the following steps preparation: each crude drug is mixed adopt the mode of conventional decocting herb to obtain decocting liquid.
9. the pharmaceutical composition of each described treatment neck of claim 1-6, shoulder, arm pain is in preparation treatment or alleviate purposes in the medicine of pains such as cervical spondylosis, scapulohumeral periarthritis, stiff neck, cervical muscle strain.
CN2010105657967A 2010-11-30 2010-11-30 Medicinal composition for treating pains of necks, shoulders and arms and preparation method and application thereof Expired - Fee Related CN102008551B (en)

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CN105311179A (en) * 2014-07-30 2016-02-10 高晓燕 Formulation for treating Bi-syndrome pain in upper extremities
CN105878776A (en) * 2016-05-27 2016-08-24 范开英 Pharmaceutical composition and preparation for treating neck, shoulder, waist and leg diseases and preparation method and application of the pharmaceutical composition and the preparation
CN104983809B (en) * 2015-07-27 2018-07-03 苏州卫生职业技术学院 A kind of Chinese medicine composition of cure scapulohumeral periarthritis and preparation method thereof

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