CN101940766A - Medicine for radically curing myocardial infarction and preparation method thereof - Google Patents
Medicine for radically curing myocardial infarction and preparation method thereof Download PDFInfo
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- CN101940766A CN101940766A CN2010105057120A CN201010505712A CN101940766A CN 101940766 A CN101940766 A CN 101940766A CN 2010105057120 A CN2010105057120 A CN 2010105057120A CN 201010505712 A CN201010505712 A CN 201010505712A CN 101940766 A CN101940766 A CN 101940766A
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Abstract
The invention discloses a medicine for radically curing myocardial infarction and a preparation method thereof. The medicine is mainly prepared from cassia twig, immature bitter orange, allium macrostemon, angelica sinensis, liquorice, trichosanthes kirilowii maxim, pinellia ternata, dried tangerine peel, green tangerine peel and the like in certain proportion by weight. The medicine can be prepared into any commonly used oral medicine preparation. The medicine of the invention has the functions of clearing away heat and toxic material, promoting blood circulation, removing blood stasis, arresting bleeding, nourishing the blood, invigorating qi, removing wind, inducing resuscitation, nourishing spirit and the like, and has quick curative effects and high radical cure rate in treating myocardial infarction.
Description
Technical field
The present invention relates to medicine of a kind of myocardial infarction disease and preparation method thereof, belong to the field of Chinese medicines.
Background technology
Myocardial infarction is the commonly encountered diseases and the frequently-occurring disease of present middle-aged and elderly people, the ambition pain of feeling oppressed during morbidity, cardiopalmus, breathe hard, weak, or do not move with twinge is fixing, pain is at Ding Chu, night pilosity, or with coughing the saliva of spitting, the cold syndrome of the stomach cold extremities, refreshing tired spontaneous perspiration, or end when doing when dull pain, angor, the touching symptom that waits endlessly, western medical treatment respite and side effect are big, and the relapse rate height can not effect a radical cure.
Summary of the invention
Therefore people to curative effect preferably Chinese medicine have great demand, up to now, also do not find relevant report about medicine of the present invention.Through verification, the thoracic obstruction of this sick subordination traditional Chinese medical science, pained category, according to the theory of Chinese medical science of " general rule is painful; painful then obstructed, and void for a long time must the stasis of blood ", the inventor is through studying repeatedly and clinical verification, finally find the medicine that the radical cure of better curative effect scheming infarction is arranged, thereby finished the present invention.
Purpose of the present invention just provides a kind of composition of medicine with radically treating myocardial infarction.
Another object of the present invention has just provided the preparation method of this composition of medicine.
Medicament selection Ramulus Cinnamomi of the present invention, Fructus Aurantii Immaturus, Bulbus Allii Macrostemonis, Radix Angelicae Sinensis, Radix Glycyrrhizae, Fructus Trichosanthis, the Rhizoma Pinelliae, Pericarpium Citri Reticulatae, Pericarpium Citri Reticulatae Viride, Caulis Bambusae In Taenia, Radix Platycodonis, Rhizoma Curcumae Longae, Rhizoma Corydalis, Fructus Toosendan, Radix Bupleuri, Semen Persicae, Eupolyphaga Seu Steleophaga, Semen Ziziphi Spinosae, Radix Polygalae, Poria, Herba Plantaginis, the Rhizoma Atractylodis Macrocephalae, Cortex Moutan, Radix Stellariae, Radix Gentianae Macrophyllae, Sanguis Draxonis, the Radix Angelicae Dahuricae, Zaocys, Agkistrodon, Polyporus, Rhizoma Coptidis, Radix Scutellariae, Folium Isatidis, Herba Violae, Radix Arnebiae (Radix Lithospermi), the Radix Aucklandiae, Fructus Citri Sarcodactylis, Cortex Magnoliae Officinalis, Olibanum, Myrrha, Radix Salviae Miltiorrhizae, Herba Ecliptae, Herba Agrimoniae, Cortex Mori, the Radix Astragali, Radix Polygoni Multiflori, Radix Ophiopogonis, Rhizoma Gastrodiae, Rhizoma Acori Graminei, Styrax, Moschus 50 Herba indigoferae Pseudotinctoriae make up, make each curative effect of medication produce synergism these drug regimens, thereby can effectively effect a radical cure the recurrence of myocardial infarction.Wherein selecting Ramulus Cinnamomi for use is that temperature is gone into the heart, lung, urinary bladder channel, and the diaphoresis expelling pathogenic factors from muscles is arranged because of its nature and flavor suffering, sweet, promoting the flow of QI-blood by warming the meridian, and supporing yang activating QI, the function of the flat gas that spins is controlled anemofrigid cold, epigastric pain, cold in blood amenorrhea, arthralgia, phlegm retention, edema, cardiopalmus.Select for use Fructus Aurantii Immaturus to be because its nature and flavor hardship, suffering, acid, temperature is gone into lung, stomach warp, and the dispelling the stagnated QI removing food stagnancy is arranged, and the function of painful abdominal mass of loosing of reducing phlegm is controlled and stopped in stagnant, and the feeling of fullness distending pain is heavy behind the dysentery, constipation, expectorant stagnate the vapour lock thoracic obstruction, blocked-up chest, gastroptosis, proctoptosis, uterine prolapse.Selecting Bulbus Allii Macrostemonis for use is that temperature is gone into lung, stomach, large intestine channel, and activating YANG and eliminating stagnation is arranged because of its nature and flavor suffering, hardship, and the circulation of qi promoting intestinal stasis relieving is controlled thoracic obstruction pain, phlegm retention cough with asthma, tenesmus.Selecting Radix Angelicae Sinensis for use is that temperature is gone into the heart, liver, spleen channel, and benefiting blood and regulating blood circulation is arranged, menstruction regulating and pain relieving, the function of loosening bowel to relieve constipation because of the sweet suffering of its nature and flavor, control menoxenia, amenorrhea stomachache , mass in the abdomen knot is poly-, metrorrhagia, and headache due to deficiency of blood, dizzy, flaccidity syndrome and arthralgia syndrome, the dryness of the intestine dyschezia, heavy after the bloody dysentery, ulcer sores, traumatic injury.Select for use Radix Glycyrrhizae to be because its nature and flavor are sweet, flat, go into spleen, stomach, lung meridian, have and middle emergency, lung moistening, detoxifcation, the function of coordinating the actions of various ingredients in a prescription, moxibustion usefulness is controlled weakness of the spleen and stomach, lack of appetite, stomachache loose stool, overstrain heating, consumptive lung disease cough, cardiopalmus, infantile convulsion; Give birth to usefulness, control laryngopharynx swelling and pain, peptic ulcer, carbuncle subcutaneous ulcer skin infection is separated poison of drug and thing and is poisoned.Select for use Fructus Trichosanthis to be because sweet, the little hardship of its nature and flavor is cold, go into lung, stomach, large intestine channel, clearing away heat and eliminating phlegm is arranged, relieving stuffiness of the chest by dispersing aggregation of pathogens, the function of moisturizing laxation is controlled the cough due to lung-heat, and the turbid Huang of expectorant is thick, obstruction of qi in the chest and cardialgia, blocked-up chest feeling of fullness, acute mastitis, acute appendicitis, constipation.Selecting the Rhizoma Pinelliae for use is because of its nature and flavor suffering, and temperature is poisonous, goes into spleen, stomach warp, and drying dampness to eliminate phlegm is arranged, stopping nausea and vomiting by lowering the adverse flow of QI, and the function of clear painful abdominal mass eliminating stagnation is controlled the damp-phlegm cold drink, vomiting, regurgitation, cough with asthma abundant expectoration, septum pectorale distension, syncope due to accumulation of phlegm headache, dizzy sleeplessness, outer subduing inflammation.Selecting Pericarpium Citri Reticulatae for use is that temperature is gone into lung, spleen channel, and regulating qi-flowing for strengthening spleen is arranged because of its nature and flavor hardship, suffering, and drying dampness to eliminate phlegm is controlled fullness in the epigastrium and chest, lack of appetite and vomiting, cough with copious phlegm.Selecting Pericarpium Citri Reticulatae Viride for use is because of its nature and flavor toil, tepor, goes into liver, gallbladder meridian, and soothing the liver dispelling the stagnated QI is arranged, and the function of eliminating stagnation expectorant is controlled breast side of body gastralgia, hernia, food stagnation, swelling of the breast, nodule in the breast, chronic malaria addiction piece.Select for use Caulis Bambusae In Taenia to be because its nature and flavor are sweet, stomach, gallbladder meridian are gone in cold, heat clearing away, removing heat from blood are arranged, reduce phlegm, the antiemetic function, control dysphoria with smothery sensation vomiting, singultus, expectorant heat syndrome cough and breathe heavily, and spit blood epistaxis, metrorrhagia, malignant histocytosis, fetal movement , Jing Epilepsy.Selecting Radix Platycodonis for use is because of its nature and flavor hardship, suffering, flat, returns lung meridian, and lung qi dispersing is arranged, and sore-throat relieving eliminates the phlegm, and the function of evacuation of pus is controlled cough with copious phlegm, and is uncomfortable in chest not smooth, pharyngalgia, hoarseness, lung abscess vomiting pus, skin infection, difficulty in discharging of pus.Select for use Rhizoma Curcumae Longae to be because its nature and flavor are arduous, temperature is gone into spleen, Liver Channel, and removing blood stasis is arranged, and sector-style is stimulated the menstrual flow, and the analgesic function is controlled trusted subordinate's feeling of fullness distending pain, brachialgia , mass in the abdomen, and women's blood stasis amenorrhea, puerperal, the stasis of blood was stopped stomachache, injury from falling down, carbuncle.Select for use Rhizoma Corydalis to be because its nature and flavor are arduous, temperature is gone into liver, stomach warp, invigorates blood circulation, and dissipating blood stasis is regulated the flow of vital energy, and the analgesic function is controlled all pains of trusted subordinate's waist knee joint, menoxenia , mass in the abdomen, metrorrhagia, puerperal blood faints, lochiorrhea, traumatic injury.Select for use Fructus Toosendan to be because its nature and flavor hardship is cold, poisonous, go into liver, stomach, small intestine meridian, have except that damp and hot, clearing away liver-fire, pain relieving, parasiticidal function is controlled epigastric pain with cold limbs due to adverseness of heat, hypochondriac pain, colic, abdominal pain due to worm stagnation.Selecting Radix Bupleuri for use is that liver, gallbladder meridian are gone in cold, and reconciling superficies and interior is arranged, and be soothing the liver because of its nature and flavor hardship, and yang invigorating is controlled alternate attack of chill and fever, fullness in the chest and hypochondriac pain, bitter taste deafness, headache and dizziness, malaria, diarrhea proctoptosis, menoxenia, uterine prolapse.Select for use Semen Persicae to be because its property bitter but sweet flavor is flat, go into the heart, liver, large intestine channel, blood stasis removing and clots absorbing is arranged, moisturize the function of laxation, control amenorrhea, mass in the abdomen, calentura blood-retention, migratory arthralgia, malaria, traumatic injury, swelling and pain due to blood stasis, the dry constipation of blood.It is salty because of its nature and flavor, cold, slightly poisonous selecting Eupolyphaga Seu Steleophaga for use, returns Liver Channel, and removing blood stasis with potent drugs blood is arranged, and the function of reuniting the fractured tendons and bones is controlled the muscles and bones folding and hindered blood stasis amenorrhea , mass in the abdomen mass in the abdomen.Select for use Semen Ziziphi Spinosae to be because its nature and flavor are sweet, flat, go into the heart, spleen, liver, gallbladder meridian, nourishing the liver is arranged, mind calming is calmed the nerves, and the function of arresting sweating is controlled restlessness of asrhenia type and insomnia, palpitation with fear palpitation with a distress feeling, excessive thirst, sweating due to debility.Selecting Radix Polygalae for use is that temperature is gone into the heart, kidney channel, and the Fructus Alpiniae Oxyphyllae of calming the nerves is arranged, and eliminates the phlegm because of its nature and flavor toil, and the function of resolving depression is controlled palpitation with fear, and is forgetful, nocturnal emission, and insomnia, cough ant phlegm, the carbuncle skin ulcer is swollen.Select for use Poria to be because its property slightly sweet flavor is flat, go into the heart, spleen, lung meridian, eliminating dampness and diuresis is arranged, the strengthening the spleen stomach function regulating, the function of mind tranquilizing and the heart calming is controlled dysuria, the edema distension, the phlegm retention cough with dyspnea, the sound of vomiting of vomitting is had loose bowels, seminal emission, stranguria with turbid discharge, palpitation with fear, forgetful.Select for use Herba Plantaginis to be because its nature and flavor are sweet, cold, go into liver, kidney, lung, small intestine meridian, clearing away heat and promoting diuresis is arranged, eliminate the phlegm removing heat from blood, antidotal function, the swollen oliguria of harnessing the river, the puckery pain of pyretic stranguria, heat-damp in summer dysentery, phlegm-heat cough, hematemesis and epistaxis, carbuncle sore tumefacting virus.Selecting the Rhizoma Atractylodis Macrocephalae for use is because its property bitter but sweet flavor, and temperature is gone into spleen, stomach warp, and spleen reinforcing is arranged, stomach reinforcing, dampness and in function, control deficient QI of the spleen and stomach, anorexia, the asthenia weak breath, deficiency-distension is had loose bowels, phlegm retention, edema, jaundice, arthralgia chiefly caused by damp pathogen, dysuria, dizziness, spontaneous perspiration, nausea uneasiness.Select for use Cortex Moutan to be because its nature and flavor are arduous, cool, go into the heart, liver, kidney channel, heat clearing away is arranged, removing heat from blood, and blood, the function of repercussive is controlled the pathogenic heat attacking blood system in febrile diseases, sends out speckle , Jing Epilepsy, and tell, be defeated in battle, have blood in stool, the hectic fever due to YIN-deficiency consumptive fever, amenorrhea , mass in the abdomen, carbuncle and ulcer is pounced on damage.Selecting Radix Stellariae for use is that liver, stomach warp are gone in cold, and the function of clearing away heat and cooling blood is arranged, and control the asthenia hectic fever due to YIN-deficiency, deficiency of YIN chronic malaria, children's's infantile malnutrition with fever weakness and emaciation because of its nature and flavor sweetness and bitterness.Select for use Radix Gentianae Macrophyllae to be because its nature and flavor toil is flat, go into liver, stomach, gallbladder meridian, expelling wind and removing dampness and blood Shujin are arranged, the function of clearing away heat and promoting diuresis, the dispelling the wind and dampness pathogens arthralgia pain, the muscles and bones contracture, jaundice is had blood in stool, osteopyrexia and fever, children's's infantile malnutrition with fever, dysuria.Select for use Sanguis Draxonis to be because its property sweet-salty is flat, go into the heart, Liver Channel, the dissipating blood stasis analgesic therapy is arranged, the function of hemostasia and promoting granulation is controlled traumatic injury and is lost, ecchymoma due to internal injury, continuous bleeding due to traumatic injury, scrofula, ecthyma unhealed for long time.Selecting the Radix Angelicae Dahuricae for use is that temperature is gone into lung, spleen, stomach warp because of its nature and flavor suffering, dispel the wind, and dampness, detumescence, the analgesic function is controlled headache, supraorbital bone pain, toothache, nasal sinusitis, cold-damp stomachache, hemorrhoidal hamorrhage anal fistula, leucorrhea with red and white discharge, ulcer sores, skin pruritus due to dryness, scabies.Select for use Zaocys to be because its property sweet-salty is flat, go into lung, spleen two warps, wind-damp dispelling is arranged, the function of the meridian dredging, dispelling the wind and dampness pathogens insensitive impediment, numbness of the skin, bone, tuberculosis of joint, rubella scabies, leprosy, tetanus, poliomyelitis.Selecting Agkistrodon for use is because of its property sweet-salty, and temperature is poisonous, goes into liver, spleen channel, and wind-damp dispelling is arranged, saturating muscles and bones, and the function that arresting convulsion is jerked, the dispelling the wind and dampness pathogens paralysis, arthralgia, leprosy, mange, infantile convulsion is twitched, tetanus, syphilitic skin lesion, scrofula malignant boil.Select for use Polyporus to be because its property slightly sweet flavor is flat, go into spleen, kidney, urinary bladder channel, the diuresis eliminating dampness by diuresis is arranged, control dysuria, the edema distension, beriberi is had loose bowels, pouring, turbid, leukorrhagia.Select for use Rhizoma Coptidis to be because its nature and flavor hardship is cold, go into the heart, liver, stomach, large intestine channel, pathogenic fire purging is arranged, dampness, detoxifcation, parasiticidal function, row pyretic toxicity, typhoid fever when controlling, intenseness of heat is vexed, feeling of fullness vomiting, bacillary dysentery, diarrhea of heat type stomachache, pulmonary tuberculosis is told, nosebleed, hematochezia, quenches one's thirst infantile malnutrition, ascariasis, pertussis, laryngopharynx swelling and pain, acute catarrhal conjunctivitis, aphtha, skin sore, eczema, the burning hot wound of soup.Select for use Radix Scutellariae to be because its nature and flavor hardship is cold, go into the heart, lung, gallbladder, large intestine channel, the removing the relative excess fire is arranged, except that damp and hot, hemostasis, antiabortive function is controlled the high fever excessive thirst, cough due to lung-heat, damp-heat dysentery, jaundice, pyretic stranguria is told, is defeated in battle, collapses, is leaked, conjunctival congestion and swelling pain, frequent fetal movement, carbuncle furuncle.Select for use Folium Isatidis to be because its nature and flavor hardship is cold, go into liver, the heart, stomach warp, heat clearing away is arranged, detoxifcation, removing heat from blood, the hemostatic function is controlled epidemic febrile disease intenseness of heat excessive thirst, influenza, acute infectious hepatitis, bacillary dysentery, acute gastroenteritis, acute pneumonia, erysipelas is spitted blood, epistaxis, jaundice, dysentery, sore throat, aphtha, swollen ulcer drug.Selecting Herba Violae for use is that GUIXIN, Liver Channel have heat-clearing and toxic substances removing because of its nature and flavor hardship, suffering, cold, and removing heat from blood repercussive function is controlled furuncle swelling toxin, carbuncle carbuncle on the back, erysipelas, venom.Selecting Radix Arnebiae (Radix Lithospermi) for use is because its nature and flavor hardship, cold, goes into percardium, Liver Channel, and removing heat from blood is arranged, invigorate blood circulation, and heat clearing away, the antidotal function is controlled warm macule, jaundice due to damp-heat, purpura tells, nosebleed, hematuria, stranguria with turbid discharge, dysentery, constipation with heat retention, burn, eczema, erysipelas, carbuncle and ulcer.Select for use the Radix Aucklandiae to be because its nature and flavor are arduous, temperature is gone into lung, liver, spleen channel, and promoting the circulation of QI to relieve pain are arranged, and the function of warming middle-JIAO for easing the stomach is controlled the invasion by pathogenic cold stagnation of QI, chest and abdomen swelling and pain, and dysentery tenesmus, colic of cold type are had loose bowels in vomiting.Select for use Fructus Citri Sarcodactylis to be because the arduous acid of its nature and flavor, temperature is gone into liver, stomach warp, regulates the flow of vital energy, and the expectorant function is treated for stomachache, and the side of body expands, and vomiting is choked every, phlegm retention cough with asthma, and can be relieved the effect of alcohol.Selecting Cortex Magnoliae Officinalis for use is that temperature is gone into spleen, stomach, large intestine channel, and warming middle-JIAO is arranged because of its nature and flavor toil, the therapeutic method to keep the adverse QI flowing downwards, and dampness, the function of expectorant is controlled breast abdomen feeling of fullness distending pain, regurgitation, vomiting, dyspepsia does not disappear, and phlegm retention is breathed with cough, the cold-damp dysentery.Select for use Olibanum to be because its nature and flavor are arduous, temperature is gone into the heart, liver, spleen channel, and regulating qi and activating blood is arranged, and analgesic therapy chases after malicious function, controls coagulation of QI-blood, trusted subordinate's pain, carbuncle pyogenic infections from tumour or sore, traumatic injury, dysmenorrhea, postnatal blood stasis twinge.Select for use Myrrha to be because its nature and flavor hardship is flat, go into Liver Channel, diffusing blood blood stasis removing is arranged, the function of subduing swelling and relieving pain is controlled and is fallen damage, incised wound, muscles and bones, all Tong , of trusted subordinate mass in the abdomen, amenorrhea, ulcer sore pain, anal fistula, diseases of the eye.Select for use Radix Salviae Miltiorrhizae to be because its nature and flavor hardship is slightly cold, go into the heart, Liver Channel, stasis-dispelling and pain-killing is arranged, promoting blood circulation to restore menstrual flow, the function of the relieving restlessness that clears away heart-fire is controlled menoxenia, amenorrhea dysmenorrhea , lumps in the chest and abdomen, breast ventral spine pain, pyretic arthralgia pain, skin infection swells and ache, dysphoria and insomnia.Selecting Herba Ecliptae for use is that liver, kidney channel are gone in cold, and removing heat from blood is arranged because of the sweet acid of its nature and flavor, hemostasis, and the kidney invigorating, the function of tonifying YIN is controlled haematemesis, hemoptysis, epistaxis, hematuria is had blood in stool, dysentery, knife injury is hemorrhage, early whitening of beard and hair, diphtheria, stranguria with turbid discharge, dysentery, pudendum pruritus due to damp pathogen.Select for use Herba Agrimoniae to be because its nature and flavor toil is flat, go into lung, liver, spleen channel, hemostasis is arranged, the function that is good for the stomach is controlled spitting of blood, spits blood, and hematuria is had blood in stool, dysentery, and bleeding not during menses, impairment caused by overstrain is taken off power, carbuncle, traumatic injury, wound hemorrhage.Select for use Cortex Mori to be because its nature and flavor are sweet, cold, go into lung, spleen channel, eliminating pathogen from the lung for relieving asthma is arranged, the function of line water detumescence is controlled dyspnea and cough due to lung-heat, spits blood edema, beriberi, dysuria.Select for use the Radix Astragali to be because its nature and flavor are sweet, warm, go into lung, spleen channel, tonifying Qi and lifting yang is arranged, benefit is defended consolidating superficial resistance, the diuretic sterilization, the function of holder skin ulcer granulation promoting, it is weak to control the deficiency of vital energy, anorexia and loose stool, sinking of QI of middle-JIAO, chronic diarrhea proctoptosis, the metrorrhagia of having blood in stool, exterior deficiency spontaneous perspiration, deficiency of vital energy edema, carbuncle is difficult bursts, and bursts for a long time and does not hold back blood deficiency and yellow complexion, interior hot water is thirsty, chronic nephritis proteinuria, diabetes.Select for use Radix Polygoni Multiflori to be because its property bitter but sweet flavor is puckery, tepor is gone into liver, kidney channel, and tonifying liver is arranged, and kidney tonifying nourishes blood, the function of dispeling the wind, the treating the liver kidney yin is lost, and sending out must be early white, the blood deficiency dizziness, and waist knee joint weakness, muscles and bones is ached, seminal emission, metrorrhagia and leukorrhagia, chronic malaria, chronic dysentery, chronic hepatitis, carbuncle, scrofula, hemorrhoidal hamorrhage, haemorrhoids.Select for use be Radix Ophiopogonis because its property sweet and slightly bitter taste is slightly cold, GUIXIN, lung, stomach warp have YIN nourishing and the production of body fluid promoting, and the function that lung moistening clears away heart-fire is controlled dryness of the lung dry cough, cough due to consumptive disease, and hinder in Tianjin, and mouth is drunk, vexed insomnia, interior-heat is quenched one's thirst, dryness of the intestine constipation, diphtheria.Select for use Rhizoma Gastrodiae to be because its nature and flavor are sweet, flat, go into Liver Channel, endogenous wind stopping is arranged, the function of arresting convulsion is controlled dizzy pupil, wind syndrome of head headache, numb limbs and tense tendons, hemiplegia, aphasia, Xiao Jing Epilepsy wind symptom.Selecting Rhizoma Acori Graminei for use is that tepor is gone into the heart, liver, spleen channel, has and has one's ideas straightened out because of its nature and flavor suffering, and eliminating phlegm is regulated the flow of vital energy, and invigorates blood circulation, diffusing wind, the function of drying, the Zhi epilepsy, syncope due to accumulation of phlegm, the calentura coma, forgetful, deafness with qi stagnation, the ambition unhappiness, stomachache, stomachache, anemofrigid-damp arthralgia, swollen ulcer drug, traumatic injury.Selecting Styrax for use is because its nature and flavor suffering, and temperature is gone into the heart, spleen channel, has and has one's ideas straightened out, and wards off dirtyly, and the analgesic function is controlled the apoplexy syncope due to accumulation of phlegm, suddenly faints breast abdomen cold type of pain, infantile convulsion.Selecting Moschus for use is because its nature and flavor suffering, and temperature is gone into the heart, spleen, Liver Channel, has and has one's ideas straightened out, ward off dirty, collateral dredging, the function of dissipating blood stasis is controlled apoplexy, syncope due to accumulation of phlegm , Jing Epilepsy, attacked by pestiferous factors unhappiness, trusted subordinate's sudden pain , mass in the abdomen hypochondriac lump, traumatic injury, swollen ulcer drug.
The specific embodiment
The drug dose of the present invention's combination also is that the inventor draws through groping in a large number to sum up, and the consumption of each component all has better curative effect in following weight range:
Ramulus Cinnamomi 6-12 gram Fructus Aurantii Immaturuss 8-15 gram Bulbus Allii Macrostemonis 3-8 grams
Radix Angelicae Sinensis 10-20 gram Radix Glycyrrhizaes 3-8 gram Fructus Trichosanthis 6-15 grams
The Rhizoma Pinelliae 6-12 gram Pericarpium Citri Reticulataes 10-20 gram Pericarpium Citri Reticulatae Virides 10-15 grams
Caulis Bambusae In Taenia 6-12 gram Radix Platycodoniss 6-15 gram Rhizoma Curcumae Longaes 8-15 grams
Rhizoma Corydalis 10-15 gram Fructus Toosendans 6-12 gram Radix Bupleuri 6-15 grams
Semen Persicae 8-15 gram Eupolyphaga Seu Steleophagas 3-6 gram Semen Ziziphi Spinosaes 10-20 grams
Radix Polygalae 10-15 gram Poria 15-20 gram Herba Plantaginiss 10-20 grams
The Rhizoma Atractylodis Macrocephalae 10-15 gram Cortex Moutans 10-20 gram Radix Stellariaes 6-15 grams
Radix Gentianae Macrophyllae 6-12 gram Sanguis Draxonis 3-8 gram Radixs Angelicae Dahuricae 6-15 grams
Zaocys 3-8 gram Agkistrodons 2-5 gram Polyporus 15-20 grams
Rhizoma Coptidis 6-12 gram Radix Scutellariaes 6-15 gram Folium Isatidiss 15-30 grams
Herba Violae 15-30 gram Radix Arnebiae (Radix Lithospermi)s 6-12 gram Radix Aucklandiae 10-20 grams
Fructus Citri Sarcodactylis 10-15 gram Cortex Magnoliae Officinalis 10-15 gram Olibanums 6-15 grams
Myrrha 6-15 gram Radix Salviae Miltiorrhizaes 15-30 gram Herba Ecliptaes 15-30 grams
Herba Agrimoniae 15-30 gram Cortex Mori 10-20 gram Radixs Astragali 15-30 grams
Radix Polygoni Multiflori 10-20 gram 10-15 gram Rhizoma Gastrodiaes Radix Ophiopogonis 6-15 grams
Rhizoma Acori Graminei 6-10 gram Styrax 3-8 gram Moschus 0.01-0.03 gram
Be preferably:
Ramulus Cinnamomi 10 gram Fructus Aurantii Immaturuss 10 gram Bulbus Allii Macrostemonis 6 grams
Radix Angelicae Sinensis 15 gram Radix Glycyrrhizaes 5 gram Fructus Trichosanthis 12 grams
The Rhizoma Pinelliae 8 gram Pericarpium Citri Reticulataes 15 gram Pericarpium Citri Reticulatae Virides 12 grams
Caulis Bambusae In Taenia 10 gram Radix Platycodoniss 10 gram Rhizoma Curcumae Longaes 10 grams
Rhizoma Corydalis 12 gram Fructus Toosendans 10 gram Radix Bupleuri 10 grams
Semen Persicae 10 gram Eupolyphaga Seu Steleophagas 4 gram Semen Ziziphi Spinosaes 15 grams
Radix Polygalae 10 gram Poria 16 gram Herba Plantaginiss 15 grams
The Rhizoma Atractylodis Macrocephalae 12 gram Cortex Moutans 15 gram Radix Stellariaes 10 grams
The Radix Gentianae Macrophyllae 10 gram Sanguis Draxonis 5 gram Radixs Angelicae Dahuricae 10 grams
Zaocys 5 gram Agkistrodons 3 gram Polyporus 18 grams
Rhizoma Coptidis 8 gram Radix Scutellariaes 10 gram Folium Isatidiss 20 grams
The Herba Violae 20 gram Radix Arnebiae (Radix Lithospermi)s 8 gram Radix Aucklandiae 15 grams
Fructus Citri Sarcodactylis 10 gram Cortex Magnoliae Officinalis 10 gram Olibanums 10 grams
Myrrha 10 gram Radix Salviae Miltiorrhizaes 15 gram Herba Ecliptaes 20 grams
The Herba Agrimoniae 15 gram Cortex Mori 15 gram Radixs Astragali 15 grams
Radix Polygoni Multiflori 15 gram 10 gram Rhizoma Gastrodiaes Radix Ophiopogonis 10 grams
Rhizoma Acori Graminei 8 gram Styrax 5 gram Moschus 0.02 gram
The preparation method of medicine of the present invention is as follows:
One, gets the raw materials ready
1, Ramulus Cinnamomi: get crude drug, remove impurity, big or small stepping is cleaned, and soaks slightly, runs through, and section or section are dried or cold drying, and cutting person removes impurity;
2, Fructus Aurantii Immaturus: get crude drug, remove impurity, clean, run through, shave dries or cold drying, and sieve removes chip;
3, Bulbus Allii Macrostemonis: get crude drug, remove impurity, fibrous root and stiff black grain, the scurf removing of winnowing with a dustpan, the time spent smashs to pieces;
4, Radix Angelicae Sinensis: choose decontamination, clean, moistening dries in the air slightly to inside and outside humidity when suitable, and section is dried;
5, Radix Glycyrrhizae: choose decontamination, clean, be soaked in water to eighty per cant when saturating, pull out, run through section, dry;
6, Fructus Trichosanthis: get crude drug, remove impurity and fruit stem, clean, flatten shredding or fritter, drying;
7, the Rhizoma Pinelliae: choose decontamination, sieve dedust bits;
8, Pericarpium Citri Reticulatae: get crude drug, remove the peel of impurity and blackening, wash quickly is clean, moistens softly, and shredding is dried or cold drying, and sieve removes chip;
9, Pericarpium Citri Reticulatae Viride: choose clean impurity, be soaked in water, pull out, run through, section is dried;
10, Caulis Bambusae In Taenia: Sucus Zingberis is fried Caulis Bambusae In Taenia: 3 liang in Rhizoma Zingiberis Recens of Caulis Bambusae In Taenia per jin, and the dregs that squeezes the juice adds 2 liang in boiled water again, fully mixes thoroughly with Caulis Bambusae In Taenia, puts a pot interior little stir-fry, takes out, and dries;
11, Radix Platycodonis: get crude drug, remove impurity, clean, run through, shave, drying, sieve removes chip;
12, Rhizoma Curcumae Longae: choose decontamination, be soaked in water, pick up, run through the back section, dry;
13, Rhizoma Corydalis: choose decontamination, be soaked in water, clean, solarization is dried in the air, and profit is even to inside and outside humidity, cuts into slices or smashes;
14, Fructus Toosendan: choose decontamination, clean, oven dry, grating or cleave in two;
15, Radix Bupleuri: choose decontamination, remove residual stem, clean silt, pull out, run through back section in time, dry immediately;
16, Semen Persicae: remove duricrust impurity, put and boil in the boiling water pot to the little wrinkle of crust, pull out, immerse in the cold water, rub with the hands and remove kind of a skin, dry, it is clean to winnow with a dustpan;
17, Eupolyphaga Seu Steleophaga: get crude drug, cleaning, drying;
18, Semen Ziziphi Spinosae: former medicine is put into the bamboo square-bottomed bamboo basket; Sink in the clear water cylinder, core is kept afloat, shell is heavy water-bed, and Semen Ziziphi Spinosae is pulled out, dries;
19, Radix Polygalae: choose decontamination, cutting, sieve dedust bits;
20, Poria: be soaked in water, clean, pull out, vexed after, cut into slices, dry;
21, Herba Plantaginis: get crude drug, remove impurity, wash quickly is clean, dries in the air cutting, drying slightly;
22, the Rhizoma Atractylodis Macrocephalae: choose clean impurity, be soaked in water, soak time should suitably be grasped according to season, climate change and Rhizoma Atractylodis Macrocephalae size, pulls out behind the bubble, runs through, and section is dried;
23, Cortex Moutan: choose decontamination, remove core, clean, run through, section is dried;
24, Radix Stellariae: choose decontamination, go reed, wash, soak slightly and pull out, run through, section is dried;
25, Radix Gentianae Macrophyllae: choose decontamination, remove removing LU, soak slightly, run through section, dry;
26, Sanguis Draxonis: wipe dust away, the knock fritter in winter dryness weather, is placed on and makes dryly in the Calx altar, takes advantage of crisp grinding into powder then;
27, the Radix Angelicae Dahuricae: choose decontamination, wash, soak, pull out and run through, slightly shine when crust does not have soapy feeling, again behind the moistening, chip drying;
28, Zaocys: Zaocys is struck off head, warm water cleaning, cutting is mixed thoroughly with yellow wine, and is vexed, puts in the pot and fries to little yellow with slow fire, and taking-up cools;
29, Agkistrodon: strike off end to end, warm water profit is soft, and dice dries, or removes osteoderm after running through with yellow wine, dries, and 100 jin of every Agkistrodons are with 50 jin of yellow wine;
30, Polyporus: clean silt particle, moisten soft section, dry;
31, Rhizoma Coptidis: choose decontamination, clean silt particle, run through, section is dried in the shade;
32, Radix Scutellariae: choose decontamination, remove residual stem, soak into or put to soak slightly in the boiled water and pull out, run through the back section, dry with cold water;
33, Folium Isatidis: choose decontamination and dead leaf, clean, moisten slightly, cutting is dried;
34, Herba Violae: get crude drug, remove impurity, clean, dry in the air cutting, drying slightly;
35, Radix Arnebiae (Radix Lithospermi): gromwell root: clean, run through Radix Arnebiae: choose decontamination, remove Seedling, cut off;
36, the Radix Aucklandiae: crude drug in whole put in the clear water clean, pull out, moistening made soft in 12-24 hours, and section is dried;
37, Fructus Citri Sarcodactylis: choose decontamination, after the water spray profit, chopping is dried;
38, Cortex Magnoliae Officinalis: be soaked in water and pull out, scrape off rough bark after running through, clean, shredding is dried;
39, Olibanum: choose the sub-impurity of shakeout;
40, Myrrha: choose decontamination, break into fragment;
41, Radix Salviae Miltiorrhizae: get crude drug, remove residual stem, impurity, clean, run through, cut sheet, drying, sieve removes chip;
42, Herba Ecliptae: choose clean impurity, remove undesirable root, clean vexed, cutting is dried;
43, Herba Agrimoniae: remove the impurity undesirable root, clean, run through, cut off, dry;
44, Cortex Mori: brush away the ash bits, clean, run through the back shredding, dry;
45, the Radix Astragali: get crude drug, remove impurity, big or small stepping is cleaned, and runs through, and cuts sheet, drying, and sieve removes chip;
46, Radix Polygoni Multiflori: choose decontamination, clean, saturating with blister to eighty per cant, to pull out, profit is even to inside and outside humidity, and section or dice dry;
47, Radix Ophiopogonis: get crude drug, remove impurity and black oil person, clean or dry in the air to half-dried draw down or flattening;
48, Rhizoma Gastrodiae: choose decontamination, big or small stepping is soaked in water to seventy percent saturating, pulls out, dries in the air slightly, and profit is even to inside and outside humidity again, and section is dried;
49, Rhizoma Acori Graminei: choose decontamination, clean, soak slightly, run through, section is dried;
50, Styrax: get crude drug, remove impurity;
51, Moschus: soak into sachet with warm water, remove fur inner membrance impurity after severing, the time spent is got Moschus core porphyrize.
Two, preparation
1, the preparation of capsule:
Ramulus Cinnamomi with described weight, Fructus Aurantii Immaturus, Bulbus Allii Macrostemonis, Radix Angelicae Sinensis, Radix Glycyrrhizae, Fructus Trichosanthis, the Rhizoma Pinelliae, Pericarpium Citri Reticulatae, Pericarpium Citri Reticulatae Viride, Caulis Bambusae In Taenia, Radix Platycodonis, Rhizoma Curcumae Longae, Rhizoma Corydalis, Fructus Toosendan, Radix Bupleuri, Semen Persicae, Eupolyphaga Seu Steleophaga, Semen Ziziphi Spinosae, Radix Polygalae, Poria, Herba Plantaginis, the Rhizoma Atractylodis Macrocephalae, Cortex Moutan, Radix Stellariae, Radix Gentianae Macrophyllae, Sanguis Draxonis, the Radix Angelicae Dahuricae, Zaocys, Agkistrodon, Polyporus, Rhizoma Coptidis, Radix Scutellariae, Folium Isatidis, Herba Violae, Radix Arnebiae (Radix Lithospermi), the Radix Aucklandiae, Fructus Citri Sarcodactylis, Cortex Magnoliae Officinalis, Olibanum, Myrrha, Radix Salviae Miltiorrhizae, Herba Ecliptae, Herba Agrimoniae, Cortex Mori, the Radix Astragali, Radix Polygoni Multiflori, Radix Ophiopogonis, Rhizoma Gastrodiae, Rhizoma Acori Graminei, Styrax, Moschus decocts with water twice, after the intense fire boiling, slow fire boiling 20 minutes, each amount of water was advisable to soak powder, merge decoction liquor twice, it is 1.35 extractum that filtering and concentrating becomes proportion, add 90-95% ethanol and carry out precipitate with ethanol, reclaim ethanol and concentrated, dry down at 45 ℃-50 ℃, it is ground into powder, incapsulates.
2, the preparation of tablet:
Ramulus Cinnamomi with described weight, Fructus Aurantii Immaturus, Bulbus Allii Macrostemonis, Radix Angelicae Sinensis, Radix Glycyrrhizae, Fructus Trichosanthis, the Rhizoma Pinelliae, Pericarpium Citri Reticulatae, Pericarpium Citri Reticulatae Viride, Caulis Bambusae In Taenia, Radix Platycodonis, Rhizoma Curcumae Longae, Rhizoma Corydalis, Fructus Toosendan, Radix Bupleuri, Semen Persicae, Eupolyphaga Seu Steleophaga, Semen Ziziphi Spinosae, Radix Polygalae, Poria, Herba Plantaginis, the Rhizoma Atractylodis Macrocephalae, Cortex Moutan, Radix Stellariae, Radix Gentianae Macrophyllae, Sanguis Draxonis, the Radix Angelicae Dahuricae, Zaocys, Agkistrodon, Polyporus, Rhizoma Coptidis, Radix Scutellariae, Folium Isatidis, Herba Violae, Radix Arnebiae (Radix Lithospermi), the Radix Aucklandiae, Fructus Citri Sarcodactylis, Cortex Magnoliae Officinalis, Olibanum, Myrrha, Radix Salviae Miltiorrhizae, Herba Ecliptae, Herba Agrimoniae, Cortex Mori, the Radix Astragali, Radix Polygoni Multiflori, Radix Ophiopogonis, Rhizoma Gastrodiae, Rhizoma Acori Graminei, Styrax, Moschus decocts with water twice, add for the first time 6 times of amounts of water, decocted 1.5 hours, add for the second time 4 times of amounts of water, decocted 1 hour, merge the extractum that twice decoction liquor is condensed into proportion 1.35, clean extractum adds 90-95% ethanol stirring, precipitation reclaims ethanol and concentrates, dry down at 45 ℃-50 ℃, be ground into powder, add the adjuvant compacting in flakes.
3, the preparation of decocting liquid:
(1) with the Ramulus Cinnamomi of described weight, Fructus Aurantii Immaturus, Bulbus Allii Macrostemonis, Radix Angelicae Sinensis, Radix Glycyrrhizae, Fructus Trichosanthis, the Rhizoma Pinelliae, Pericarpium Citri Reticulatae, Pericarpium Citri Reticulatae Viride, Caulis Bambusae In Taenia, Radix Platycodonis, Rhizoma Curcumae Longae, Rhizoma Corydalis, Fructus Toosendan, Radix Bupleuri, Semen Persicae, Eupolyphaga Seu Steleophaga, Semen Ziziphi Spinosae, Radix Polygalae, Poria, Herba Plantaginis, the Rhizoma Atractylodis Macrocephalae, Cortex Moutan, Radix Stellariae, Radix Gentianae Macrophyllae, Sanguis Draxonis, the Radix Angelicae Dahuricae, Zaocys, Agkistrodon, Polyporus, Rhizoma Coptidis, Radix Scutellariae, Folium Isatidis, Herba Violae, Radix Arnebiae (Radix Lithospermi), the Radix Aucklandiae, Fructus Citri Sarcodactylis, Cortex Magnoliae Officinalis, Olibanum, Myrrha, Radix Salviae Miltiorrhizae, Herba Ecliptae, Herba Agrimoniae, Cortex Mori, the Radix Astragali, Radix Polygoni Multiflori, Radix Ophiopogonis, Rhizoma Gastrodiae, Rhizoma Acori Graminei, Styrax, Moschus decocts with water, add for the first time 2 times of amounts of water, intense fire decocts boiling 30 minutes, and reuse slow fire boiling 20 minutes promptly.Decoction liquor is the liquid of taking medicine patient's morning for the first time.
(2) medicinal residues after will filtering for the first time add 1.5 times of amounts of water, decoct boiling, and the reuse slow fire boiling promptly get the decoction liquor second time in 20 minutes, the liquid of taking medicine the evening that is the patient.
4, particulate preparation:
Ramulus Cinnamomi with described weight, Fructus Aurantii Immaturus, Bulbus Allii Macrostemonis, Radix Angelicae Sinensis, Radix Glycyrrhizae, Fructus Trichosanthis, the Rhizoma Pinelliae, Pericarpium Citri Reticulatae, Pericarpium Citri Reticulatae Viride, Caulis Bambusae In Taenia, Radix Platycodonis, Rhizoma Curcumae Longae, Rhizoma Corydalis, Fructus Toosendan, Radix Bupleuri, Semen Persicae, Eupolyphaga Seu Steleophaga, Semen Ziziphi Spinosae, Radix Polygalae, Poria, Herba Plantaginis, the Rhizoma Atractylodis Macrocephalae, Cortex Moutan, Radix Stellariae, Radix Gentianae Macrophyllae, Sanguis Draxonis, the Radix Angelicae Dahuricae, Zaocys, Agkistrodon, Polyporus, Rhizoma Coptidis, Radix Scutellariae, Folium Isatidis, Herba Violae, Radix Arnebiae (Radix Lithospermi), the Radix Aucklandiae, Fructus Citri Sarcodactylis, Cortex Magnoliae Officinalis, Olibanum, Myrrha, Radix Salviae Miltiorrhizae, Herba Ecliptae, Herba Agrimoniae, Cortex Mori, the Radix Astragali, Radix Polygoni Multiflori, Radix Ophiopogonis, Rhizoma Gastrodiae, Rhizoma Acori Graminei, Styrax, Moschus decocts with water twice, add for the first time 6 times of amounts of water, decocted 1.5 hours, add for the second time 4 times of amounts of water, decocted 1 hour, merging decoction liquor for the second time, to be condensed into proportion be 1.35 extractum, extractum added 90-95% ethanol, stir, precipitation reclaims ethanol and concentrates, dry down at 45 ℃-50 ℃, add adjuvant, make granule.
5, the preparation of unguentum:
Ramulus Cinnamomi with described weight, Fructus Aurantii Immaturus, Bulbus Allii Macrostemonis, Radix Angelicae Sinensis, Radix Glycyrrhizae, Fructus Trichosanthis, the Rhizoma Pinelliae, Pericarpium Citri Reticulatae, Pericarpium Citri Reticulatae Viride, Caulis Bambusae In Taenia, Radix Platycodonis, Rhizoma Curcumae Longae, Rhizoma Corydalis, Fructus Toosendan, Radix Bupleuri, Semen Persicae, Eupolyphaga Seu Steleophaga, Semen Ziziphi Spinosae, Radix Polygalae, Poria, Herba Plantaginis, the Rhizoma Atractylodis Macrocephalae, Cortex Moutan, Radix Stellariae, Radix Gentianae Macrophyllae, Sanguis Draxonis, the Radix Angelicae Dahuricae, Zaocys, Agkistrodon, Polyporus, Rhizoma Coptidis, Radix Scutellariae, Folium Isatidis, Herba Violae, Radix Arnebiae (Radix Lithospermi), the Radix Aucklandiae, Fructus Citri Sarcodactylis, Cortex Magnoliae Officinalis, Olibanum, Myrrha, Radix Salviae Miltiorrhizae, Herba Ecliptae, Herba Agrimoniae, Cortex Mori, the Radix Astragali, Radix Polygoni Multiflori, Radix Ophiopogonis, Rhizoma Gastrodiae, Rhizoma Acori Graminei, Styrax, Moschus decocts with water twice, add for the first time 6 times of amounts of water, decocted 1.5 hours, add for the second time 4 times of amounts of water, decocted 1 hour, merging twice decoction liquor, to be condensed into proportion be 1.35 extractum.
The active component of medicine of the present invention can add preparation required various conventional adjuvant during different dosage form, is prepared into any peroral dosage form commonly used with the method for Chinese medicinal of routine, as tablet, capsule, oral liquid, granule, unguentum etc.
Medicine of the present invention has heat-clearing and toxic substances removing, promoting blood circulation and breaking stagnation, the beneficial blood that stops blooding, the dampness removing heat from blood nourishes blood and enriches blood, QI invigorating is removed wind, the function such as repose of having one's ideas straightened out, it is fast to be used for the treatment of curative effects such as myocardial infarction, the radical rate height, below further set forth effective achievement of medicine of the present invention by testing example, these tests comprise that medicine of the present invention (following satisfactory flesh infarction) animal toxicity test and clinical observation test.
[test example 1] medicine of the present invention is to the toxicity test report of rabbit
Get 40 of West Germany does, body weight 2.0-2.5kg divides two groups, wherein one group is the excess test group, another group is the normal amount test group, and the super quantity group is 15ml/kg, and normal amount is 10ml/kg, administering mode is the administration by gavage administration, once a day, serve on January, observe the administration reaction every day, the result shows that two groups of rabbit activities, diet are normal, and medicine does not have bad toxic and side effects.
The clinical observation material of [test example 2] medicine of the present invention
1, physical data:
Accept out-patient's 780 examples for medical treatment, 30-40 years old 80 age example, 40-50 years old 200 example, 500 examples more than 50 years old.
2, diagnostic criteria:
Light-duty myocardial infarction morbidity 1-3 months, patient's blood pressure is fluctuated, the time slight headache, dizziness, uncomfortable in chest, chest pain are arranged, the palpitation with fear severe palpitation, weak, irritability is done the Color Sonography inspection and is found to have slight myocardial infarction phenomenon.Heavy myocardial infarction, medical history are all different, are through after the urgent rescue of doctor trained in Western medicine mostly, non-life-threatening, but the myocardial infarction phenomenon is still very serious, usually uncomfortable in chest, chest pain, the thorough back of pain, dizzy, muddled a, heart, arrhythmia, limbs fatigue, lazy speech lacks symptoms such as moving, through the inspection of doctor's device, belong to seriousness myocardial infarction disease.
3, Therapeutic Method:
Decocting liquid by measuring crude drug, put into the container herbal decoction routinely of boiling medicine, services once every day twice sooner or later, and one month is a course of treatment, a light-duty course of treatment, heavy two courses of treatment.Tablet: oral three times of every day, each 8, one month is a course of treatment, a light-duty course of treatment, heavy two courses of treatment.Capsule: oral 3 times of every day, each 10, one month is a course of treatment, a light-duty course of treatment, heavy two courses of treatment.Granule: oral three times of every day, each 1(12 gram), one month is a course of treatment, a light-duty course of treatment, heavy two courses of treatment.Unguentum: oral three times of every day, each 18ml, one month is a course of treatment, a light-duty course of treatment, heavy two courses of treatment.
4, efficacy assessment standard:
Produce effects: light, heavy myocardial infarction after treatment, this disease transference cure of patient, it is normal that patient's body constitution is recovered, and disappears through the color ultrasound examination blocking part, follows up a case by regular visits to 3-5 years no recidivists.
Take a turn for the better: the myocardial infarction symptom progressively alleviates or disappears, and the patient feels good, and it is normal that body constitution is recovered substantially.
Invalid: as not have.
5, therapeutic outcome (seeing the following form):
In the treatment of a course of treatment, with light-duty myocardial infarction patient's 280 examples of Drug therapy of the present invention, produce effects 200 examples, 80 examples take a turn for the better, the nonsignificant zero example, total effective rate 100% is in the treatment of two courses of treatment, with the heavy myocardial infarction patient of Drug therapy of the present invention 500 examples, produce effects 480 examples, 2 examples that take a turn for the better, the nonsignificant zero example, total effective rate is 100%.
Claims (3)
1. medicine that effects a radical cure myocardial infarction, it is characterized in that: it is to be made by the crude drug in the following weight range:
Ramulus Cinnamomi 6-12 gram Fructus Aurantii Immaturuss 8-15 gram Bulbus Allii Macrostemonis 3-8 grams
Radix Angelicae Sinensis 10-20 gram Radix Glycyrrhizaes 3-8 gram Fructus Trichosanthis 6-15 grams
The Rhizoma Pinelliae 6-12 gram Pericarpium Citri Reticulataes 10-20 gram Pericarpium Citri Reticulatae Virides 10-15 grams
Caulis Bambusae In Taenia 6-12 gram Radix Platycodoniss 6-15 gram Rhizoma Curcumae Longaes 8-15 grams
Rhizoma Corydalis 10-15 gram Fructus Toosendans 6-12 gram Radix Bupleuri 6-15 grams
Semen Persicae 8-15 gram Eupolyphaga Seu Steleophagas 3-6 gram Semen Ziziphi Spinosaes 10-20 grams
Radix Polygalae 10-15 gram Poria 15-20 gram Herba Plantaginiss 10-20 grams
The Rhizoma Atractylodis Macrocephalae 10-15 gram Cortex Moutans 10-20 gram Radix Stellariaes 6-15 grams
Radix Gentianae Macrophyllae 6-12 gram Sanguis Draxonis 3-8 gram Radixs Angelicae Dahuricae 6-15 grams
Zaocys 3-8 gram Agkistrodons 2-5 gram Polyporus 15-20 grams
Rhizoma Coptidis 6-12 gram Radix Scutellariaes 6-15 gram Folium Isatidiss 15-30 grams
Herba Violae 15-30 gram Radix Arnebiae (Radix Lithospermi)s 6-12 gram Radix Aucklandiae 10-20 grams
Fructus Citri Sarcodactylis 10-15 gram Cortex Magnoliae Officinalis 10-15 gram Olibanums 6-15 grams
Myrrha 6-15 gram Radix Salviae Miltiorrhizaes 15-30 gram Herba Ecliptaes 15-30 grams
Herba Agrimoniae 15-30 gram Cortex Mori 10-20 gram Radixs Astragali 15-30 grams
Radix Polygoni Multiflori 10-20 gram 10-15 gram Rhizoma Gastrodiaes Radix Ophiopogonis 6-15 grams
Rhizoma Acori Graminei 6-10 gram Styrax 3-8 gram Moschus 0.01-0.03 gram.
2. the medicine of radical cure myocardial infarction according to claim 1, wherein the consumption of each crude drug is:
Ramulus Cinnamomi 10 gram Fructus Aurantii Immaturuss 10 gram Bulbus Allii Macrostemonis 6 grams
Radix Angelicae Sinensis 15 gram Radix Glycyrrhizaes 5 gram Fructus Trichosanthis 12 grams
The Rhizoma Pinelliae 8 gram Pericarpium Citri Reticulataes 15 gram Pericarpium Citri Reticulatae Virides 12 grams
Caulis Bambusae In Taenia 10 gram Radix Platycodoniss 10 gram Rhizoma Curcumae Longaes 10 grams
Rhizoma Corydalis 12 gram Fructus Toosendans 10 gram Radix Bupleuri 10 grams
Semen Persicae 10 gram Eupolyphaga Seu Steleophagas 4 gram Semen Ziziphi Spinosaes 15 grams
Radix Polygalae 10 gram Poria 16 gram Herba Plantaginiss 15 grams
The Rhizoma Atractylodis Macrocephalae 12 gram Cortex Moutans 15 gram Radix Stellariaes 10 grams
The Radix Gentianae Macrophyllae 10 gram Sanguis Draxonis 5 gram Radixs Angelicae Dahuricae 10 grams
Zaocys 5 gram Agkistrodons 3 gram Polyporus 18 grams
Rhizoma Coptidis 8 gram Radix Scutellariaes 10 gram Folium Isatidiss 20 grams
The Herba Violae 20 gram Radix Arnebiae (Radix Lithospermi)s 8 gram Radix Aucklandiae 15 grams
Fructus Citri Sarcodactylis 10 gram Cortex Magnoliae Officinalis 10 gram Olibanums 10 grams
Myrrha 10 gram Radix Salviae Miltiorrhizaes 15 gram Herba Ecliptaes 20 grams
The Herba Agrimoniae 15 gram Cortex Mori 15 gram Radixs Astragali 15 grams
Radix Polygoni Multiflori 15 gram 10 gram Rhizoma Gastrodiaes Radix Ophiopogonis 10 grams
Rhizoma Acori Graminei 8 gram Styrax 5 gram Moschus 0.02 gram.
3. according to the preparation method of claim 1 or 2 described medicines, it is characterized in that: it comprises the following steps:
(1) gets the raw materials ready
(1) Ramulus Cinnamomi: get crude drug, remove impurity, big or small stepping is cleaned, and soaks slightly, runs through, and section or section are dried or cold drying, and cutting person removes impurity;
(2) Fructus Aurantii Immaturus: get crude drug, remove impurity, clean, run through, shave dries or cold drying, and sieve removes chip;
(3) Bulbus Allii Macrostemonis: get crude drug, remove impurity, fibrous root and stiff black grain, the scurf removing of winnowing with a dustpan, the time spent smashs to pieces;
(4) Radix Angelicae Sinensis: choose decontamination, clean, moistening dries in the air slightly to inside and outside humidity when suitable, and section is dried;
(5) Radix Glycyrrhizae: choose decontamination, clean, be soaked in water to eighty per cant when saturating, pull out, run through section, dry;
(6) Fructus Trichosanthis: get crude drug, remove impurity and fruit stem, clean, flatten shredding or fritter, drying;
(7) Rhizoma Pinelliae: choose decontamination, sieve dedust bits;
(8) Pericarpium Citri Reticulatae: get crude drug, remove the peel of impurity and blackening, wash quickly is clean, moistens softly, and shredding is dried or cold drying, and sieve removes chip;
(9) Pericarpium Citri Reticulatae Viride: choose clean impurity, be soaked in water, pull out, run through, section is dried;
(10) Caulis Bambusae In Taenia: Sucus Zingberis is fried Caulis Bambusae In Taenia: 3 liang in Rhizoma Zingiberis Recens of Caulis Bambusae In Taenia per jin, and the dregs that squeezes the juice adds 2 liang in boiled water again, fully mixes thoroughly with Caulis Bambusae In Taenia, puts a pot interior little stir-fry, takes out, and dries;
(11) Radix Platycodonis: get crude drug, remove impurity, clean, run through, shave, drying, sieve removes chip;
(12) Rhizoma Curcumae Longae: choose decontamination, be soaked in water, pick up, run through the back section, dry;
(13) Rhizoma Corydalis: choose decontamination, be soaked in water, clean, solarization is dried in the air, and profit is even to inside and outside humidity, cuts into slices or smashes;
(14) Fructus Toosendan: choose decontamination, clean, oven dry, grating or cleave in two;
(15) Radix Bupleuri: choose decontamination, remove residual stem, clean silt, pull out, run through back section in time, dry immediately;
(16) Semen Persicae: remove duricrust impurity, put and boil in the boiling water pot to the little wrinkle of crust, pull out, immerse in the cold water, rub with the hands and remove kind of a skin, dry, it is clean to winnow with a dustpan;
(17) Eupolyphaga Seu Steleophaga: get crude drug, cleaning, drying;
(18) Semen Ziziphi Spinosae: former medicine is put into the bamboo square-bottomed bamboo basket; Sink in the clear water cylinder, core is kept afloat, shell is heavy water-bed, and Semen Ziziphi Spinosae is pulled out, dries;
(19) Radix Polygalae: choose decontamination, cutting, sieve dedust bits;
(20) Poria: be soaked in water, clean, pull out, vexed after, cut into slices, dry;
(21) Herba Plantaginis: get crude drug, remove impurity, wash quickly is clean, dries in the air cutting, drying slightly;
(22) Rhizoma Atractylodis Macrocephalae: choose clean impurity, be soaked in water, soak time should suitably be grasped according to season, climate change and Rhizoma Atractylodis Macrocephalae size, pulls out behind the bubble, runs through, and section is dried;
(23) Cortex Moutan: choose decontamination, remove core, clean, run through, section is dried;
(24) Radix Stellariae: choose decontamination, go reed, wash, soak slightly and pull out, run through, section is dried;
(25) Radix Gentianae Macrophyllae: choose decontamination, remove removing LU, soak slightly, run through section, dry;
(26) Sanguis Draxonis: wipe dust away, the knock fritter in winter dryness weather, is placed on and makes dryly in the Calx altar, takes advantage of crisp grinding into powder then;
(27) Radix Angelicae Dahuricae: choose decontamination, wash, soak, pull out and run through, slightly shine when crust does not have soapy feeling, again behind the moistening, chip drying;
(28) Zaocys: Zaocys is struck off head, warm water cleaning, cutting is mixed thoroughly with yellow wine, and is vexed, puts in the pot and fries to little yellow with slow fire, and taking-up cools;
(29) Agkistrodon: strike off end to end, warm water profit is soft, and dice dries, or removes osteoderm after running through with yellow wine, dries, and 100 jin of every Agkistrodons are with 50 jin of yellow wine;
(30) Polyporus: clean silt particle, moisten soft section, dry;
(31) Rhizoma Coptidis: choose decontamination, clean silt particle, run through, section is dried in the shade;
(32) Radix Scutellariae: choose decontamination, remove residual stem, soak into or put to soak slightly in the boiled water and pull out, run through the back section, dry with cold water;
(33) Folium Isatidis: choose decontamination and dead leaf, clean, moisten slightly, cutting is dried;
(34) Herba Violae: get crude drug, remove impurity, clean, dry in the air cutting, drying slightly;
(35) Radix Arnebiae (Radix Lithospermi): gromwell root: clean, run through Radix Arnebiae: choose decontamination, remove Seedling, cut off;
(36) Radix Aucklandiae: crude drug in whole put in the clear water clean, pull out, moistening made soft in 12-24 hours, and section is dried;
(37) Fructus Citri Sarcodactylis: choose decontamination, after the water spray profit, chopping is dried;
(38) Cortex Magnoliae Officinalis: be soaked in water and pull out, scrape off rough bark after running through, clean, shredding is dried;
(39) Olibanum: choose the sub-impurity of shakeout;
(40) Myrrha: choose decontamination, break into fragment;
(41) Radix Salviae Miltiorrhizae: get crude drug, remove residual stem, impurity, clean, run through, cut sheet, drying, sieve removes chip;
(42) Herba Ecliptae: choose clean impurity, remove undesirable root, clean vexed, cutting is dried;
(43) Herba Agrimoniae: remove the impurity undesirable root, clean, run through, cut off, dry;
(44) Cortex Mori: brush away the ash bits, clean, run through the back shredding, dry;
(45) Radix Astragali: get crude drug, remove impurity, big or small stepping is cleaned, and runs through, and cuts sheet, drying, and sieve removes chip;
(46) Radix Polygoni Multiflori: choose decontamination, clean, saturating with blister to eighty per cant, to pull out, profit is even to inside and outside humidity, and section or dice dry;
(47) Radix Ophiopogonis: get crude drug, remove impurity and black oil person, clean or dry in the air to half-dried draw down or flattening;
(48) Rhizoma Gastrodiae: choose decontamination, big or small stepping is soaked in water to seventy percent saturating, pulls out, dries in the air slightly, and profit is even to inside and outside humidity again, and section is dried;
(49) Rhizoma Acori Graminei: choose decontamination, clean, soak slightly, run through, section is dried;
(50) Styrax: get crude drug, remove impurity;
(51) Moschus: soak into sachet with warm water, remove fur inner membrance impurity after severing, the time spent is got Moschus core porphyrize;
(2) preparation
(1) preparation of capsule:
Ramulus Cinnamomi with described weight, Fructus Aurantii Immaturus, Bulbus Allii Macrostemonis, Radix Angelicae Sinensis, Radix Glycyrrhizae, Fructus Trichosanthis, the Rhizoma Pinelliae, Pericarpium Citri Reticulatae, Pericarpium Citri Reticulatae Viride, Caulis Bambusae In Taenia, Radix Platycodonis, Rhizoma Curcumae Longae, Rhizoma Corydalis, Fructus Toosendan, Radix Bupleuri, Semen Persicae, Eupolyphaga Seu Steleophaga, Semen Ziziphi Spinosae, Radix Polygalae, Poria, Herba Plantaginis, the Rhizoma Atractylodis Macrocephalae, Cortex Moutan, Radix Stellariae, Radix Gentianae Macrophyllae, Sanguis Draxonis, the Radix Angelicae Dahuricae, Zaocys, Agkistrodon, Polyporus, Rhizoma Coptidis, Radix Scutellariae, Folium Isatidis, Herba Violae, Radix Arnebiae (Radix Lithospermi), the Radix Aucklandiae, Fructus Citri Sarcodactylis, Cortex Magnoliae Officinalis, Olibanum, Myrrha, Radix Salviae Miltiorrhizae, Herba Ecliptae, Herba Agrimoniae, Cortex Mori, the Radix Astragali, Radix Polygoni Multiflori, Radix Ophiopogonis, Rhizoma Gastrodiae, Rhizoma Acori Graminei, Styrax, Moschus decocts with water twice, each amount of water was advisable to soak powder, merge decoction liquor twice, it is 1.35 extractum that filtering and concentrating becomes proportion, add 90-95% ethanol and carry out precipitate with ethanol, reclaim ethanol and concentrated, dry down at 45 ℃-50 ℃, it is ground into powder, incapsulates;
(2) preparation of tablet:
Ramulus Cinnamomi with described weight, Fructus Aurantii Immaturus, Bulbus Allii Macrostemonis, Radix Angelicae Sinensis, Radix Glycyrrhizae, Fructus Trichosanthis, the Rhizoma Pinelliae, Pericarpium Citri Reticulatae, Pericarpium Citri Reticulatae Viride, Caulis Bambusae In Taenia, Radix Platycodonis, Rhizoma Curcumae Longae, Rhizoma Corydalis, Fructus Toosendan, Radix Bupleuri, Semen Persicae, Eupolyphaga Seu Steleophaga, Semen Ziziphi Spinosae, Radix Polygalae, Poria, Herba Plantaginis, the Rhizoma Atractylodis Macrocephalae, Cortex Moutan, Radix Stellariae, Radix Gentianae Macrophyllae, Sanguis Draxonis, the Radix Angelicae Dahuricae, Zaocys, Agkistrodon, Polyporus, Rhizoma Coptidis, Radix Scutellariae, Folium Isatidis, Herba Violae, Radix Arnebiae (Radix Lithospermi), the Radix Aucklandiae, Fructus Citri Sarcodactylis, Cortex Magnoliae Officinalis, Olibanum, Myrrha, Radix Salviae Miltiorrhizae, Herba Ecliptae, Herba Agrimoniae, Cortex Mori, the Radix Astragali, Radix Polygoni Multiflori, Radix Ophiopogonis, Rhizoma Gastrodiae, Rhizoma Acori Graminei, Styrax, Moschus decocts with water twice, add for the first time 6 times of amounts of water, decocted 1.5 hours, add for the second time 4 times of amounts of water, decocted 1 hour, merge the extractum that twice decoction liquor is condensed into proportion 1.35, clean extractum adds 90-95% ethanol stirring, precipitation reclaims ethanol and concentrates, dry down at 45 ℃-50 ℃, be ground into powder, add the adjuvant compacting in flakes;
(3) preparation of decocting liquid:
1. with the Ramulus Cinnamomi of described weight, Fructus Aurantii Immaturus, Bulbus Allii Macrostemonis, Radix Angelicae Sinensis, Radix Glycyrrhizae, Fructus Trichosanthis, the Rhizoma Pinelliae, Pericarpium Citri Reticulatae, Pericarpium Citri Reticulatae Viride, Caulis Bambusae In Taenia, Radix Platycodonis, Rhizoma Curcumae Longae, Rhizoma Corydalis, Fructus Toosendan, Radix Bupleuri, Semen Persicae, Eupolyphaga Seu Steleophaga, Semen Ziziphi Spinosae, Radix Polygalae, Poria, Herba Plantaginis, the Rhizoma Atractylodis Macrocephalae, Cortex Moutan, Radix Stellariae, Radix Gentianae Macrophyllae, Sanguis Draxonis, the Radix Angelicae Dahuricae, Zaocys, Agkistrodon, Polyporus, Rhizoma Coptidis, Radix Scutellariae, Folium Isatidis, Herba Violae, Radix Arnebiae (Radix Lithospermi), the Radix Aucklandiae, Fructus Citri Sarcodactylis, Cortex Magnoliae Officinalis, Olibanum, Myrrha, Radix Salviae Miltiorrhizae, Herba Ecliptae, Herba Agrimoniae, Cortex Mori, the Radix Astragali, Radix Polygoni Multiflori, Radix Ophiopogonis, Rhizoma Gastrodiae, Rhizoma Acori Graminei, Styrax, Moschus decocts with water, add for the first time 2 times of amounts of water, intense fire decocts boiling 30 minutes, promptly decoction liquor was the liquid of taking medicine patient's morning for the first time in 20 minutes in the reuse slow fire boiling;
2. the medicinal residues after will filtering for the first time add 1.5 times of amounts of water, decoct boiling, and the reuse slow fire boiling promptly get the decoction liquor second time in 20 minutes, the liquid of taking medicine the evening that is the patient;
(4) particulate preparation:
Ramulus Cinnamomi with described weight, Fructus Aurantii Immaturus, Bulbus Allii Macrostemonis, Radix Angelicae Sinensis, Radix Glycyrrhizae, Fructus Trichosanthis, the Rhizoma Pinelliae, Pericarpium Citri Reticulatae, Pericarpium Citri Reticulatae Viride, Caulis Bambusae In Taenia, Radix Platycodonis, Rhizoma Curcumae Longae, Rhizoma Corydalis, Fructus Toosendan, Radix Bupleuri, Semen Persicae, Eupolyphaga Seu Steleophaga, Semen Ziziphi Spinosae, Radix Polygalae, Poria, Herba Plantaginis, the Rhizoma Atractylodis Macrocephalae, Cortex Moutan, Radix Stellariae, Radix Gentianae Macrophyllae, Sanguis Draxonis, the Radix Angelicae Dahuricae, Zaocys, Agkistrodon, Polyporus, Rhizoma Coptidis, Radix Scutellariae, Folium Isatidis, Herba Violae, Radix Arnebiae (Radix Lithospermi), the Radix Aucklandiae, Fructus Citri Sarcodactylis, Cortex Magnoliae Officinalis, Olibanum, Myrrha, Radix Salviae Miltiorrhizae, Herba Ecliptae, Herba Agrimoniae, Cortex Mori, the Radix Astragali, Radix Polygoni Multiflori, Radix Ophiopogonis, Rhizoma Gastrodiae, Rhizoma Acori Graminei, Styrax, Moschus decocts with water twice, add for the first time 6 times of amounts of water, decocted 1.5 hours, add for the second time 4 times of amounts of water, decocted 1 hour, merging decoction liquor for the second time, to be condensed into proportion be 1.35 extractum, extractum added 90-95% ethanol, stir, precipitation reclaims ethanol and concentrates, dry down at 45 ℃-50 ℃, add adjuvant, make granule;
(5) preparation of unguentum:
Ramulus Cinnamomi with described weight, Fructus Aurantii Immaturus, Bulbus Allii Macrostemonis, Radix Angelicae Sinensis, Radix Glycyrrhizae, Fructus Trichosanthis, the Rhizoma Pinelliae, Pericarpium Citri Reticulatae, Pericarpium Citri Reticulatae Viride, Caulis Bambusae In Taenia, Radix Platycodonis, Rhizoma Curcumae Longae, Rhizoma Corydalis, Fructus Toosendan, Radix Bupleuri, Semen Persicae, Eupolyphaga Seu Steleophaga, Semen Ziziphi Spinosae, Radix Polygalae, Poria, Herba Plantaginis, the Rhizoma Atractylodis Macrocephalae, Cortex Moutan, Radix Stellariae, Radix Gentianae Macrophyllae, Sanguis Draxonis, the Radix Angelicae Dahuricae, Zaocys, Agkistrodon, Polyporus, Rhizoma Coptidis, Radix Scutellariae, Folium Isatidis, Herba Violae, Radix Arnebiae (Radix Lithospermi), the Radix Aucklandiae, Fructus Citri Sarcodactylis, Cortex Magnoliae Officinalis, Olibanum, Myrrha, Radix Salviae Miltiorrhizae, Herba Ecliptae, Herba Agrimoniae, Cortex Mori, the Radix Astragali, Radix Polygoni Multiflori, Radix Ophiopogonis, Rhizoma Gastrodiae, Rhizoma Acori Graminei, Styrax, Moschus decocts with water twice, add for the first time 6 times of amounts of water, decocted 1.5 hours, add for the second time 4 times of amounts of water, decocted 1 hour, merging twice decoction liquor, to be condensed into proportion be 1.35 extractum.
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Publication number | Priority date | Publication date | Assignee | Title |
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CN1088816A (en) * | 1993-01-01 | 1994-07-06 | 胡保华 | " Huxinxiangtong " powder medicine for treating heart diseases |
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2010
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Patent Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
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CN1088816A (en) * | 1993-01-01 | 1994-07-06 | 胡保华 | " Huxinxiangtong " powder medicine for treating heart diseases |
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