CN101856471B - Chinese medicinal composition for tonifying kidney and strengthening body - Google Patents

Chinese medicinal composition for tonifying kidney and strengthening body Download PDF

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CN101856471B
CN101856471B CN2010102008692A CN201010200869A CN101856471B CN 101856471 B CN101856471 B CN 101856471B CN 2010102008692 A CN2010102008692 A CN 2010102008692A CN 201010200869 A CN201010200869 A CN 201010200869A CN 101856471 B CN101856471 B CN 101856471B
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fructus
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herba
semen
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李忠全
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Abstract

The invention relates to a Chinese medicinal composition for tonifying kidney and strengthening body, which is characterized in that: the composition is prepared by decocting the following raw materials with water: sea horse, placenta, hairy antler, dog's testis and penis, actinolite, epimedium herb and the like. The invention also relates to a method for preparing the Chinese medicinal composition and application in preparing a medicament for treating nephropathy.

Description

The Chinese medicine composition that is used for kidney-tonifying health-care
Technical field
The present invention relates to the field of Chinese medicines, particularly, the present invention relates to a kind of Chinese medicine composition that is used for kidney-tonifying health-care, it is characterized in that processing through decocting: Hippocampus, Placenta Hominis, Cornu Cervi Pantotrichum, Testis et Pentis Canis, Actinolitum, Herba Epimedii etc. by following raw material components.The invention still further relates to the method for preparing and the application in the medicine of preparation treatment nephropathy of said Chinese medicine composition.
Background technology
Kidney is people's a life the congenital foundation, is that kidney-Yang has confidential relation with human body g and D reproduction water liquid metabolism and respiratory system.
Kidney master marrow is given birth to brain, presides over all ergasias of human body, and kidney essense is sufficient, and is then resourceful; Come to one's autumn, kidney essense gas degradation, the neuroendocrine imbalance, gonad function is not enough; Sex hormones secretion reduces, and causes kidney qi to be lost more, soreness of the waist and knees will occur, spiritlessness and weakness, and the cold limb of row is weary, dysphoria with feverish sensation in the chest palms and soles; Insomnia and dreamful sleep, forgetful, cardiopalmus is nervous; Impotence and premature ejaculation, nocturia is frequent, and one's ears rang and spots danced before one's eyes, bladder cold-damp, fidgets due to deficiency night sweat, hypertension, the high card of blood glucose.
Nephropathy is the general name of various kidney diseases, is a kind of diseases of urinary system of serious harm health, is prone to outbreak repeatedly, is difficult to cure.Modern medicine still lacks the Therapeutic Method and the medicine of satisfactory effect to primary disease, and Drug therapy mainly still adopts glucocorticoid and immunosuppressant and anti symptom treatment.
The treatment by Chinese herbs nephropathy has advantages such as prescription is flexible, side effect is little.Using Chinese medicine should follow fewer but better principle, obtain better curative effect, is to advance the modernization of Chinese medicine, promotes the only way which must be passed that Chinese medicine goes to the world.
How the traditional Chinese medical science controls the nephropathy problem is paid close attention to by much human always; No matter be that nephrotic syndrome patient, IGA nephrotic or chronic nephritis, glomerulonephritis, henoch Schonlein purpura nephritis, lupus nephritis patient can be because of western medical treatments, albuminuria, hematuria are transferred to hope on the Chinese traditional treatment nephropathy repeatedly.
Treatment by Chinese herbs nephropathy five big advantages
One of treatment by Chinese herbs nephropathy advantage: system's medication can determination of treatment based on pathogenesis obtained through differentiation of symptoms and signs: according to patient's the state of an illness, body constitution etc., the active substance in the ingredient can automatic targeting location kidney focus, finds the intrinsic cell of impaired kidney, and it is carried out repairing and treating.To reach optimum curative effect, guarantee effective percentage and cure rate.
Treatment by Chinese herbs nephropathy advantage two, good effect, cure rate is high.
Treatment by Chinese herbs nephropathy advantage three, the strong body of toxin expelling, reduce recurrence.
Treatment by Chinese herbs nephropathy advantage five, suit the taste of both old and young, be widely used.
Treatment by Chinese herbs nephropathy advantage four, safe and reliable, have no side effect.
Summary of the invention
China's traditional Chinese medical science derives from Taoist school, the history in existing more than 5,000 year of Chinese Taoism.China's Chinese medical culture is the doctor, and there is a well-known saying " ten roads, nine doctors " saying in the successive dynasties.The inventor is that first the 28 generation road doctor successor that sends mixes in Taoist school, and religious name " clever profound son " Taoist through concentrating on studies, has invented a kind of Chinese medicine preparation that has good efficacy for nephropathy.This medicine ability kidney-tonifying health-care key brain, benefit is mended marrow, warming and invigorating kidney deficiency, invigorating QI and tranquilization.It has spermatogenesis, consolidate, the characteristics of life lengthening.
Particularly, the present invention provides the following:
1. a Chinese medicine composition that is used for kidney-tonifying health-care is characterized in that being processed through decocting by following raw material components: Hippocampus, Placenta Hominis, Cornu Cervi Pantotrichum, Testis et Pentis Canis, Actinolitum, Herba Epimedii, Flos Caryophylli winged euonymus, Herba Epimedii, Semen Cuscutae, Fructus Ligustri Lucidi; Fructus Lycii, Concha Ostreae, Rhizoma Dioscoreae, the Radix Polygoni Multiflori, Fructus Rosae Laevigatae, ZHUANGYANGGUO, Herba Cistanches, HUBAZI, Radix Rehmanniae Preparata, Fructus Schisandrae Chinensis, SHENGHUANG flower; The Leptoradix Ginseng, Poria, Niu Xi, Radix Dipsaci, Radix Morindae Officinalis, Semen Allii Tuberosi, Fructus Rubi, Semen Coicis, Semen Mori, Colla Corii Asini; Flos Carthami, Penis et testis cervi, Radix Codonopsis, Poria cum Radix Pini, the Cortex Eucommiae, Squama Manis, Caulis Spatholobi, the Qin nine, Arillus Longan, Colla cornus cervi; Fructus Jujubae core, Radix Polygalae, SHENGHUANG is smart, Caulis Polygoni Multiflori, Cordyceps, Herba Asari, Fructus Corni, pin sun, Gecko, hops; Fructus Schisandrae Chinensis, Solenognathus, Embryo cervi, Testis Et penis Bovis seu Bubali, Carapax Trionycis, Semen Oroxyli, Carapax Et Plastrum Testudinis, Herba Taxilli, Herba Dendrobii, and Bulbus Lilii.
2. according to above 1 described Chinese medicine composition, wherein said Chinese medicine composition is to exist with the aqueous solution form.
3. according to above 2 described Chinese medicine compositions, the concentration of wherein said Chinese medicine composition in aqueous solution is about 30%.
4. according to each described Chinese medicine composition of above 1-3, the part by weight of wherein said raw material components is following: hippocampus 3 weight portion, Placenta Hominis 20 weight portions, Cornu Cervi Pantotrichum 20 weight portions, Testis et Pentis Canis 25 weight portions, Actinolitum 15 weight portions; Herba Epimedii 2 weight portions, Flos Caryophylli winged euonymus 15 weight portions, Herba Epimedii 15 weight portions, Semen Cuscutae 10 weight portions, Fructus Ligustri Lucidi 15 weight portions, Fructus Lycii 25 weight portions; Concha Ostreae 15 weight portions, Rhizoma Dioscoreae 10 weight portions, the Radix Polygoni Multiflori 10 weight portions, Fructus Rosae Laevigatae 15 weight portions, ZHUANGYANGGUO 15 weight portions, Herba Cistanches 15 weight portions; HUBAZI 10 weight portions, Radix Rehmanniae Preparata 20 weight portions, Fructus Schisandrae Chinensis 10 weight portions, SHENGHUANG is spent 10 weight portions, Leptoradix Ginseng's 15 weight portions, Poria 20 weight portions; Cattle sunset 15 weight portion, Radix Dipsaci 15 weight portions, Radix Morindae Officinalis 15 weight portions, Semen Allii Tuberosi 29 weight portions, Fructus Rubi 15 weight portions, Semen Coicis 15 weight portions; Semen Mori 15 weight portions, Colla Corii Asini 15 weight portions, Flos Carthami 3 weight portions, Penis et testis cervi 20 weight portions, Radix Codonopsis 15 weight portions, Poria cum Radix Pini's 15 weight portions; The Cortex Eucommiae 20 weight portions, Squama Manis 15 weight portions, Caulis Spatholobi 10 weight portions, the Qin's 9 10 weight portions, Arillus Longan 10 weight portions, Colla cornus cervi 15 weight portions; Fructus Jujubae core 20 weight portions, Radix Polygalae 20 weight portions, smart 15 weight portions of SHENGHUANG, Caulis Polygoni Multiflori 20 weight portions, Cordyceps 5 weight portions; Herba Asari 5 weight portions, Fructus Corni 15 weight portions are sold positive 10 weight portions, 2 pairs of Geckos, hops 10 weight portions; Fructus Schisandrae Chinensis 10 weight portions, 3 of Solenognathus, Embryo cervi 15 weight portions, Testis Et penis Bovis seu Bubali 20 weight portions, Carapax Trionycis 10 weight portions; Semen Oroxyli 15 weight portions, Carapax Et Plastrum Testudinis 10 weight portions, Herba Taxilli 15 weight portions, Herba Dendrobii 15 weight portions and Bulbus Lilii 10 weight portions.Only if point out in addition or obviously and context inconsistent, weight portion as herein described all refers to dry weight.
5. according to each described Chinese medicine composition of above 1-4, it is the method preparation through may further comprise the steps:
1) mixes each raw material components, cold water soak;
2) be heated to the water boiling; With
3) boil with little fire, accomplish decocting.
6. according to above 5 described Chinese medicine compositions, it is the method preparation through may further comprise the steps:
1) mixes each raw material components, cold water soak 10 minutes;
2) be heated to the water boiling; With
3) boiled 20-30 minute with little fire, decocting becomes 30% drug solns.
7. method for preparing Chinese medicine composition said method comprising the steps of:
1) mixes Hippocampus, Placenta Hominis, Cornu Cervi Pantotrichum, Testis et Pentis Canis, Actinolitum, Herba Epimedii, Flos Caryophylli winged euonymus, Herba Epimedii, Semen Cuscutae, Fructus Ligustri Lucidi, Fructus Lycii, Concha Ostreae, Rhizoma Dioscoreae; The Radix Polygoni Multiflori, Fructus Rosae Laevigatae, ZHUANGYANGGUO, Herba Cistanches, HUBAZI, Radix Rehmanniae Preparata, Fructus Schisandrae Chinensis, SHENGHUANG flower, Leptoradix Ginseng, Poria, Niu Xi, Radix Dipsaci, Radix Morindae Officinalis; Semen Allii Tuberosi, Fructus Rubi, Semen Coicis, Semen Mori, Colla Corii Asini, Flos Carthami, Penis et testis cervi, Radix Codonopsis, Poria cum Radix Pini, the Cortex Eucommiae, Squama Manis, Caulis Spatholobi; The Qin nine, Arillus Longan, Colla cornus cervi, Fructus Jujubae core, Radix Polygalae, SHENGHUANG is smart, Caulis Polygoni Multiflori, Cordyceps, Herba Asari, Fructus Corni, pin sun, Gecko; Hops, Fructus Schisandrae Chinensis, Solenognathus, Embryo cervi, Testis Et penis Bovis seu Bubali, Carapax Trionycis, Semen Oroxyli, Carapax Et Plastrum Testudinis, Herba Taxilli, Herba Dendrobii, and Bulbus Lilii, cold water soak;
2) be heated to the water boiling; With
3) boil with little fire, accomplish decocting.
8. according to above 7 method, wherein said Chinese medicine composition is to exist with the aqueous solution form, and preferably the raw material components of each in step 1) proportioning by weight is following: hippocampus 3 weight portion, Placenta Hominis 20 weight portions, Cornu Cervi Pantotrichum 20 weight portions, Testis et Pentis Canis 25 weight portions; Actinolitum 15 weight portions, Herba Epimedii 2 weight portions, Flos Caryophylli winged euonymus 15 weight portions, Herba Epimedii 15 weight portions, Semen Cuscutae 10 weight portions, Fructus Ligustri Lucidi 15 weight portions; Fructus Lycii 25 weight portions, Concha Ostreae 15 weight portions, Rhizoma Dioscoreae 10 weight portions, the Radix Polygoni Multiflori 10 weight portions, Fructus Rosae Laevigatae 15 weight portions, ZHUANGYANGGUO 15 weight portions; Herba Cistanches 15 weight portions, HUBAZI 10 weight portions, Radix Rehmanniae Preparata 20 weight portions, Fructus Schisandrae Chinensis 10 weight portions, SHENGHUANG is spent 10 weight portions, Leptoradix Ginseng's 15 weight portions; Poria 20 weight portions, cattle sunset 15 weight portion, Radix Dipsaci 15 weight portions, Radix Morindae Officinalis 15 weight portions, Semen Allii Tuberosi 29 weight portions, Fructus Rubi 15 weight portions; Semen Coicis 15 weight portions, Semen Mori 15 weight portions, Colla Corii Asini 15 weight portions, Flos Carthami 3 weight portions, Penis et testis cervi 20 weight portions, Radix Codonopsis 15 weight portions; Poria cum Radix Pini's 15 weight portions, the Cortex Eucommiae 20 weight portions, Squama Manis 15 weight portions, Caulis Spatholobi 10 weight portions, the Qin's 9 10 weight portions, Arillus Longan 10 weight portions; Colla cornus cervi 15 weight portions, Fructus Jujubae core 20 weight portions, Radix Polygalae 20 weight portions, smart 15 weight portions of SHENGHUANG, Caulis Polygoni Multiflori 20 weight portions, Cordyceps 5 weight portions; Herba Asari 5 weight portions, Fructus Corni 15 weight portions are sold positive 10 weight portions, 2 pairs of Geckos, hops 10 weight portions, Fructus Schisandrae Chinensis 10 weight portions; 3 of Solenognathus, Embryo cervi 15 weight portions, Testis Et penis Bovis seu Bubali 20 weight portions, Carapax Trionycis 10 weight portions, Semen Oroxyli 15 weight portions; Carapax Et Plastrum Testudinis 10 weight portions, Herba Taxilli 15 weight portions, Herba Dendrobii 15 weight portions and Bulbus Lilii 10 weight portions, the concentration of more preferably said Chinese medicine composition in aqueous solution is about 30%.
9. according to above 8 method, said method comprising the steps of:
1) mixes each raw material components, cold water soak 10 minutes;
2) be heated to the water boiling; With
3) boiled 20-30 minute with little fire, decocting becomes 30% drug solns.
10. the application of each Chinese medicine composition in the medicine of preparation treatment nephropathy among the above 1-6, preferred said nephropathy is selected from renal insufficiency, chronic renal failure, chronic glomerulonephritis, IgA nephropathy, diabetic nephropathy and hypertensive nephropathy.
The specific embodiment
Hereinafter is described the reference implementation example in detail the present invention, and said embodiment only is intended as illustrative explanation the present invention, rather than intention restriction scope of the present invention.Scope of the present invention is specifically limited accompanying Claim.
Embodiment 1
Preparation embodiment
Chinese medicine composition of the present invention can be prepared as follows: get the hippocampus 3 gram respectively, Placenta Hominis 20 grams, Cornu Cervi Pantotrichum 20 grams, Testis et Pentis Canis 25 grams, Actinolitum 15 grams, Herba Epimedii 2 grams, Flos Caryophylli winged euonymus 15 grams, Herba Epimedii 15 grams; Semen Cuscutae 10 grams, Fructus Ligustri Lucidi 15 grams, Fructus Lycii 25 grams, Concha Ostreae 15 grams, Rhizoma Dioscoreae 10 grams, the Radix Polygoni Multiflori 10 grams, Fructus Rosae Laevigatae 15 grams, ZHUANGYANGGUO 15 grams; Herba Cistanches 15 grams, HUBAZI 10 grams, Radix Rehmanniae Preparata 20 restrains, Fructus Schisandrae Chinensis 10 grams, SHENGHUANG is spent 10 grams, Leptoradix Ginseng's 15 grams, Poria 20 grams, cattle sunset 15 restrain; Radix Dipsaci 15 grams, Radix Morindae Officinalis 15 grams, Semen Allii Tuberosi 29 grams, Fructus Rubi 15 grams, Semen Coicis 15 grams, Semen Mori 15 grams, Colla Corii Asini 15 grams, Flos Carthami 3 grams; Penis et testis cervi 20 grams, Radix Codonopsis 15 grams, Poria cum Radix Pini's 15 grams, the Cortex Eucommiae 20 grams, Squama Manis 15 grams, Caulis Spatholobi 10 grams, the Qin's 9 10 grams, Arillus Longan 10 grams; Colla cornus cervi 15 grams, Fructus Jujubae core 20 grams, Radix Polygalae 20 grams, smart 15 grams of SHENGHUANG, Caulis Polygoni Multiflori 20 grams, Cordyceps 5 grams, Herba Asari 5 grams, Fructus Corni 15 grams; Pin sun 10 grams, 2 pairs of Geckos, hops 10 grams, Fructus Schisandrae Chinensis 10 grams, 3 of Solenognathus, Embryo cervi 15 grams, Testis Et penis Bovis seu Bubali 20 grams, Carapax Trionycis 10 grams; Semen Oroxyli 15 grams, Carapax Et Plastrum Testudinis 10 grams, Herba Taxilli 15 grams, Herba Dendrobii 15 grams and Bulbus Lilii 10 grams, and mix, obtain the raw material of Chinese medicine mixture.Above-mentioned raw material of Chinese medicine all can be available from Beijing pharmacy of Tongrentang.
With above-mentioned raw material of Chinese medicine mixture cold water soak 10 minutes, water was opened, and little fiery 20-30 minute, decocting became 30% drug solns.
Application process:
Get the drug solns of above-mentioned preparation embodiment preparation, give the patient oral, each 300-600 milliliter, sooner or later respectively once.
Embodiment 2
The inventor unexpectedly finds various nephropathy are all had the curative effect of excellence through the of the present invention middle drug solns of embodiment 1 preparation.
The typical clinical report is described below at present:
Purpose is observed the clinical efficacy of Chinese medicine composition of the present invention to diabetic nephropathy (DN) azotemia patient.
Method will be selected in patient and be divided into treatment group and each 20 example of matched group at random, and the treatment group is taken Chinese medicine composition solution of the present invention, and respectively once, each 500 milliliters, matched group is taken NIAODUQING KELI sooner or later, and 1~2 time/d, be 4 weeks the course of treatment.Observe carbohydrate metabolism, blood pressure, serum creatinine (SCr), blood urea nitrogen (BUN), 24h urine protein, UAE index situations of change such as (urinary protein excretion rates) before and after the treatment.Difference not statistically significant (P>0.05) before treatment group as a result and the treatment of matched group each item observation index; There is statistical significance (P<0.01) the treatment back with the preceding comparing difference of treatment; Two groups of treatment backs are relatively except influencing not statistically significant (P>0.05) to carbohydrate metabolism, all the other each item indexs are all with treatment group curative effect be dominant (P<0.05).
Conclusion Chinese medicine composition solution of the present invention can be treated diabetic nephropathy azotemia patient.
Diabetic nephropathy (diabetic nephropathy DN) is the common a kind of chronic complicating diseases of diabetes.DN gets into the clinical albuminuria phase, and (the 24h urine protein quantitation>0.5g), it is irreversible that kidney injury becomes, and renal dysfunction can occur simultaneously.Take Chinese medicine composition solution of the present invention, observe its influence DN patient's azotemia, satisfactory effect, existing report is as follows.
1 data and method
1.1 physical data
MethodsThe cases enrolled is all from inpatient during Linzhou City, Henan Province hospital department of endocrinology year August March to 2009 calendar year 2001; Totally 40 examples; Each 20 example of wherein treatment group and matched group; Two groups of sexes, age, the course of disease, BMI aspect difference not statistically significants such as (body mass indexs) have comparability (P>0.05).
1.2 case choice criteria
1.2.1DN diagnostic criteria [Mogensen CE.Natural history of renal functional abnormalities in human diabetes mellitus:from normallbuminuria to incipient and overt nephropathy.In:Brenner BM; Stein JH; Ed.The kidney in Diabetes Mellitus.New York:Livingstone, 1989:19-49.] according to the Mogensen diagnostic criteria.The IV phase: clinical albuminuria phase.Routine urinalysis albumen lasting masculin, urine protein quantitation>0.5g/24h.GFR (glomerular filtration rate) descends gradually, UAE (urinary protein excretion rate)>200 μ g/min.
Meet the Western medicine diagnose standard 1.2.2 include the case standard in, DN IV phase patient all can include the observation case in.
1.2.3 get rid of case standard (1) gestation, women breast-feeding their children and drug allergy history person arranged; (2) other severe complications person is arranged; (3) be unwilling to cooperate and the psychotic; (4) there is metabolism such as diabetic ketoacidosis disorderly and merge the severe infections person in nearly January; (5) IDDM person; (6) the renal function person of going down that causes of other reasons.
1.3 Therapeutic Method
To be selected in patient and be divided into treatment group and each 20 example of matched group at random, two groups of patient base treatments are constant, comprise Diet Therapy, insulin blood sugar control, blood pressure lowering, essential amino acid therapy etc.The treatment group gives Chinese medicine composition solution of the present invention; Matched group is taken NIAODUQING KELI (Kangchen Pharmaceutical Co., Ltd., Guangzhou, 5g/ bag), 5g/ time, 3~4 times/d.4 weeks were 1 course of treatment, observed 1 course of treatment altogether.Carry out diabetes education, diet, psychotherapy, blood sugar monitoring etc. in the observation process of taking medicine simultaneously.
1.4 observation index
Carbohydrate metabolism, blood pressure, 24h urinaryalbumin, serum creatinine (SCr), blood urea nitrogen (BUN), UAE (urinary protein excretion rate) etc. before and after the treatment.
1.5 statistical analysis
Adopt the SPSS12.0 software kit to carry out data analysis.(x ± s) expression adopts the t check to measurement data with mean ± standard deviation.
2 results
2.1 fasting glucose (FBG), post-prandial glycemia (PBG), glycolated hemoglobin (HbAlC) are relatively before and after two groups of treatments
Two groups of preceding more equal not statistically significants (P>0.05) of treatment, all there is statistical significance (P<0.01) two groups of treatment backs with the preceding comparing difference of treatment, two groups of treatment back comparing difference not statistically significants (P>0.05).
2.2 blood pressure, 24h urinaryalbumin and UAE are relatively before and after two groups of treatments
Two groups of preceding equal not statistically significants of comparing difference (P>0.05) of treatment, all there is statistical significance (P<0.01) two groups of treatment backs with the preceding comparing difference of treatment, and two groups of treatment back comparing differences have statistical significance (P<0.05).
2.3 renal function relatively before and after two groups of treatments
Two groups of preceding equal not statistically significants of comparing difference (P>0.05) of treatment, two groups of treatment back different time sections all have statistical significance (P<0.01) than the preceding difference of treatment, and two groups of treatment back comparing differences have statistical significance (P<0.05).
Embodiment 3
Purpose is inquired into the Chinese medicine composition solution treatment albuminuretic clinical effectiveness that nephropathy caused of the present invention.
Method is chosen 150 routine albuminuria patients in Linzhou City, Henan Province hospital, cover all kinds nephropathy patient, five types such as nephritic proteinuria, nephrotic syndrome albuminuria, proteinuria caused by diabetic nephropathy, henoch Schonlein purpura nephritis albuminuria, lupus nephritis albuminuria.Wherein, male 90 examples, women 60 examples; Age 5-15 year 33 examples, 15-28 year 55 examples, 28-35 year 42 examples, 20 examples more than 35 years old.Glomerulonephritis 50 examples, nephrotic syndrome 35 examples, diabetic nephropathy 20 examples, henoch Schonlein purpura nephritis 25 examples, lupus nephritis 20 examples.The course of disease 6 months is with interior 43 examples, the 6-12 months 48 example, 59 examples more than 1 year, the course of disease is the shortest 3 months, and is the longest 4 years.Urine protein ++ ++ 30 examples, +++78 examples, ++ 33 examples ,+9 examples.Accompany slight edema 45 examples, moderate edema 59 examples, severe edema 46 examples.Companion's hematuria +++37 examples, ++ 52 examples.Accompanied with hypertension 74 examples, blood pressure is up to 180/140mmhg.Adopting oral Chinese medicine composition solution therapy for treating of the present invention, was to observe change of illness state 1 course of treatment with 3 months.
After the result treated a course of treatment, albuminuria was turned out cloudy, edema obviously disappears, and 150 routine albuminuria patients, 104 examples of fully recovering account for 69%; Treat after 3 months, urine protein is turned out cloudy, no edema, and controlling of blood pressure is good, and continuing does not have recurrence; State of an illness basic controlling 27 examples account for 18%, after treatment March, and urine protein-or+-, continue there is not recurrence; 13 examples that sb.'s illness took a favorable turn account for 7%, after treatment March, and urine protein+-more than, there is not recurrence; Invalid 6 examples account for 4%, treatment March, urine protein only descend one+or do not have explicitly and change.Total effective rate reaches 96%.
Conclusion is used traditional Chinese medicine composition for treating nephropathy albuminuria of the present invention, can effectively improve kidney and systemic microcirculation blood flow, improves and repairing kidney functions, reaches to eliminate albuminuretic purpose.
Embodiment 4
More how clinical instance.
1, Wang Hu (man) gives birth to the stone official group Nan Bo village of going to the countryside, pool, Linzhou City, Henan Province; 56 years old now; Symptoms such as soreness of the waist and knees, pain, myasthenia of limbs were arranged in the past; Continued more than 4 years: take Chinese medicine composition of the present invention from lunar calendar June 13 in 1993, one week symptoms such as back soreness of the waist and knees, pain obviously alleviate the back recovery from illness of two weeks.
2, paid cloud (woman) 42 years old now, live Ze Xia village, Wu Longzhen township, symptoms such as insomnia and dreamful sleep, cardiopalmus is nervous, tinnitus is frequent are often arranged; Continued more than 6 years; Once took multiple Western medicine, can't effect a radical cure, took kidney-tonifying health-care brain-strengthening pellet on the 17th from December in 1998; Symptom obviously alleviates after two weeks, back recovery from illness all around.
3, new side (man) is 40 years old; Wu Longzhen township, Linzhou City, Henan Province Ze Xia people from village; Often there are soreness of the waist and knees, myasthenia of limbs, dreaminess at night, insomnia, night sweat, evening to urinate and wait symptom often; Took Chinese medicine composition of the present invention JIUYUE 21 from i985, sb.'s illness took a favorable turn after two weeks, the back recovery from illness of six week of clothes.
4, Chang Fugui (man) is 45 years old; Live group Bei Shandi village, Li Jia stockaded village, Lin Qi town, Linzhou City, Henan Province; Ill 5 years, concrete symptom have kidney not degradation disease, gonad function is not enough, often spiritlessness and weakness, the cold limb of row is weary, nocturia is frequent, impotence and premature ejaculation, bladder cold-damp etc., that doctor trained in Western medicine is cured is invalid for many years, on February 12nd, 1989 began to take Chinese medicine composition of the present invention; Disease alleviates after two weeks, the back recovery from illness of 5 weeks.
5, this medicine is tried out since calendar year 2001 by the Zhang Haicui vice-president in commune hospital, Five Dragons town, Linzhou City, Henan Province, has treated 230 many cases so far, and cure rate accounts for more than 95%.
6, Yang Lingxian (woman) is 39 years old, and Linzhou City, Henan Province tea is denied the little stone roller Chang Jiazhuan people of group in township, has that long-term insomnia and dreamful sleep, cardiopalmus are nervous, go out symptoms such as night sweat, headache night, obvious effects is just arranged, back recovery from illness all around two weeks after taking Chinese medicine composition of the present invention.
7, Zhang Liushuan (man) is 46 years old; Live Five Dragons town, Linzhou City, Henan Province sieve group sieve village; Once suffered from a deficiency of the kidney, impotence and premature ejaculation, often soreness of waist and ache in legs, perspire at night, symptom such as nocturia is frequent; It is red on November 13rd, 1992 to begin to take the kidney-tonifying health-care brain-strengthening, and obvious effects was just arranged after two weeks, the back recovery from illness of 7 weeks.
8, Hao Minghua (woman) is 32 years old; Live 5 groups in stone official group Zhao Guan village, Five Dragons town, Linzhou City, Henan Province; Because of neuroendocrine imbalance and kidney qi loss cause that frequent lumbocrural pain, general weakness, spiritlessness and weakness, whole body are ice-cold, night insomnia and dreamful sleep, restless, tinnitus day is dizzy; On October 21st, 1993 began to take Chinese medicine composition of the present invention, after two weeks positive effect was arranged, the back recovery from illness of six weeks.

Claims (10)

1. a Chinese medicine composition that is used for kidney-tonifying health-care is characterized in that being processed through decocting by following raw material components: Hippocampus, Placenta Hominis, Cornu Cervi Pantotrichum, Testis et Pentis Canis, Actinolitum, Herba Epimedii, Flos Caryophylli winged euonymus, Herba Epimedii; Semen Cuscutae, Fructus Ligustri Lucidi, Fructus Lycii, Concha Ostreae, Rhizoma Dioscoreae, the Radix Polygoni Multiflori, Fructus Rosae Laevigatae, ZHUANGYANGGUO, Herba Cistanches; HUBAZI, Radix Rehmanniae Preparata, Fructus Schisandrae Chinensis, SHENGHUANG flower, Leptoradix Ginseng, Poria, Niu Xi, Radix Dipsaci, Radix Morindae Officinalis; Semen Allii Tuberosi, Fructus Rubi, Semen Coicis, Semen Mori, Colla Corii Asini, Flos Carthami, Penis et testis cervi, Radix Codonopsis; Poria cum Radix Pini, the Cortex Eucommiae, Squama Manis, Caulis Spatholobi, the Qin nine, Arillus Longan, Colla cornus cervi, Fructus Jujubae core; Radix Polygalae, SHENGHUANG is smart, Caulis Polygoni Multiflori, Cordyceps, Herba Asari, Fructus Corni, pin sun, Gecko; Hops, Fructus Schisandrae Chinensis, Solenognathus, Embryo cervi, Testis Et penis Bovis seu Bubali, Carapax Trionycis, Semen Oroxyli, Carapax Et Plastrum Testudinis; Herba Taxilli, Herba Dendrobii, and Bulbus Lilii, the part by weight of wherein said raw material components is following: hippocampus 3 weight portion, Placenta Hominis 20 weight portions, Cornu Cervi Pantotrichum 20 weight portions, Testis et Pentis Canis 25 weight portions, Actinolitum 15 weight portions; Herba Epimedii 2 weight portions, Flos Caryophylli winged euonymus 15 weight portions, Herba Epimedii 15 weight portions, Semen Cuscutae 10 weight portions, Fructus Ligustri Lucidi 15 weight portions, Fructus Lycii 25 weight portions, Concha Ostreae 15 weight portions, Rhizoma Dioscoreae 10 weight portions; The Radix Polygoni Multiflori 10 weight portions, Fructus Rosae Laevigatae 15 weight portions, ZHUANGYANGGUO 15 weight portions, Herba Cistanches 15 weight portions, HUBAZI 10 weight portions, Radix Rehmanniae Preparata 20 weight portions, Fructus Schisandrae Chinensis 10 weight portions, SHENGHUANG is spent 10 weight portions; Leptoradix Ginseng's 15 weight portions, Poria 20 weight portions, cattle sunset 15 weight portion, Radix Dipsaci 15 weight portions, Radix Morindae Officinalis 15 weight portions, Semen Allii Tuberosi 29 weight portions, Fructus Rubi 15 weight portions, Semen Coicis 15 weight portions; Semen Mori 15 weight portions, Colla Corii Asini 15 weight portions, Flos Carthami 3 weight portions, Penis et testis cervi 20 weight portions, Radix Codonopsis 15 weight portions, Poria cum Radix Pini's 15 weight portions, the Cortex Eucommiae 20 weight portions, Squama Manis 15 weight portions; Caulis Spatholobi 10 weight portions, the Qin's 9 10 weight portions, Arillus Longan 10 weight portions, Colla cornus cervi 15 weight portions, Fructus Jujubae core 20 weight portions, Radix Polygalae 20 weight portions, smart 15 weight portions of SHENGHUANG, Caulis Polygoni Multiflori 20 weight portions; Cordyceps 5 weight portions, Herba Asari 5 weight portions, Fructus Corni 15 weight portions are sold positive 10 weight portions, 2 pairs of Geckos, hops 10 weight portions, Fructus Schisandrae Chinensis 10 weight portions, 3 of Solenognathus; Embryo cervi 15 weight portions, Testis Et penis Bovis seu Bubali 20 weight portions, Carapax Trionycis 10 weight portions, Semen Oroxyli 15 weight portions, Carapax Et Plastrum Testudinis 10 weight portions, Herba Taxilli 15 weight portions, Herba Dendrobii 15 weight portions and Bulbus Lilii 10 weight portions.
2. Chinese medicine composition according to claim 1, wherein said Chinese medicine composition are to exist with the aqueous solution form.
3. Chinese medicine composition according to claim 2, the concentration of wherein said Chinese medicine composition in aqueous solution is 30%.
4. according to each described Chinese medicine composition of claim 1-3, it is the method preparation through may further comprise the steps:
1) mixes each raw material components, cold water soak;
2) be heated to the water boiling; With
3) boil with little fire, accomplish decocting.
5. Chinese medicine composition according to claim 4, it is the method preparation through may further comprise the steps:
1) mixes each raw material components, cold water soak 10 minutes;
2) be heated to the water boiling; With
3) boiled 20-30 minute with little fire, decocting becomes 30% drug solns.
6. method for preparing Chinese medicine composition said method comprising the steps of:
1) mixes Hippocampus, Placenta Hominis, Cornu Cervi Pantotrichum, Testis et Pentis Canis, Actinolitum, Herba Epimedii, Flos Caryophylli winged euonymus, Herba Epimedii, Semen Cuscutae; Fructus Ligustri Lucidi, Fructus Lycii, Concha Ostreae, Rhizoma Dioscoreae, the Radix Polygoni Multiflori, Fructus Rosae Laevigatae, ZHUANGYANGGUO, Herba Cistanches, HUBAZI; Radix Rehmanniae Preparata, Fructus Schisandrae Chinensis, SHENGHUANG flower, Leptoradix Ginseng, Poria, Niu Xi, Radix Dipsaci, Radix Morindae Officinalis, Semen Allii Tuberosi; Fructus Rubi, Semen Coicis, Semen Mori, Colla Corii Asini, Flos Carthami, Penis et testis cervi, Radix Codonopsis, Poria cum Radix Pini, the Cortex Eucommiae; Squama Manis, Caulis Spatholobi, the Qin nine, Arillus Longan, Colla cornus cervi, Fructus Jujubae core, Radix Polygalae, SHENGHUANG is smart, Caulis Polygoni Multiflori; Cordyceps, Herba Asari, Fructus Corni, pin sun, Gecko, hops, Fructus Schisandrae Chinensis, Solenognathus, Embryo cervi; Testis Et penis Bovis seu Bubali, Carapax Trionycis, Semen Oroxyli, Carapax Et Plastrum Testudinis, Herba Taxilli, Herba Dendrobii, and Bulbus Lilii, cold water soak, wherein each raw material components proportioning by weight is following: the hippocampus 3 weight portion; Placenta Hominis 20 weight portions, Cornu Cervi Pantotrichum 20 weight portions, Testis et Pentis Canis 25 weight portions, Actinolitum 15 weight portions, Herba Epimedii 2 weight portions, Flos Caryophylli winged euonymus 15 weight portions, Herba Epimedii 15 weight portions, Semen Cuscutae 10 weight portions, Fructus Ligustri Lucidi 15 weight portions; Fructus Lycii 25 weight portions, Concha Ostreae 15 weight portions, Rhizoma Dioscoreae 10 weight portions, the Radix Polygoni Multiflori 10 weight portions, Fructus Rosae Laevigatae 15 weight portions, ZHUANGYANGGUO 15 weight portions, Herba Cistanches 15 weight portions, HUBAZI 10 weight portions, Radix Rehmanniae Preparata 20 weight portions; Fructus Schisandrae Chinensis 10 weight portions, SHENGHUANG is spent 10 weight portions, Leptoradix Ginseng's 15 weight portions, Poria 20 weight portions, cattle sunset 15 weight portion, Radix Dipsaci 15 weight portions, Radix Morindae Officinalis 15 weight portions, Semen Allii Tuberosi 29 weight portions, Fructus Rubi 15 weight portions; Semen Coicis 15 weight portions, Semen Mori 15 weight portions, Colla Corii Asini 15 weight portions, Flos Carthami 3 weight portions, Penis et testis cervi 20 weight portions, Radix Codonopsis 15 weight portions, Poria cum Radix Pini's 15 weight portions, the Cortex Eucommiae 20 weight portions, Squama Manis 15 weight portions; Caulis Spatholobi 10 weight portions, the Qin's 9 10 weight portions, Arillus Longan 10 weight portions, Colla cornus cervi 15 weight portions, Fructus Jujubae core 20 weight portions, Radix Polygalae 20 weight portions, smart 15 weight portions of SHENGHUANG, Caulis Polygoni Multiflori 20 weight portions; Cordyceps 5 weight portions, Herba Asari 5 weight portions, Fructus Corni 15 weight portions are sold positive 10 weight portions, 2 pairs of Geckos, hops 10 weight portions, Fructus Schisandrae Chinensis 10 weight portions, 3 of Solenognathus; Embryo cervi 15 weight portions, Testis Et penis Bovis seu Bubali 20 weight portions, Carapax Trionycis 10 weight portions, Semen Oroxyli 15 weight portions, Carapax Et Plastrum Testudinis 10 weight portions, Herba Taxilli 15 weight portions, Herba Dendrobii 15 weight portions and Bulbus Lilii 10 weight portions;
2) be heated to the water boiling; With
3) boil with little fire, accomplish decocting.
7. according to the method for claim 6, wherein said Chinese medicine composition is to exist with the aqueous solution form.
8. according to the method for claim 7, the concentration of wherein said Chinese medicine composition in aqueous solution is 30%.
9. according to Claim 8 method said method comprising the steps of:
1) mixes each raw material components, cold water soak 10 minutes;
2) be heated to the water boiling; With
3) boiled 20-30 minute with little fire, decocting becomes 30% drug solns.
10. the application of each Chinese medicine composition in the medicine of preparation treatment nephropathy among the claim 1-5, said nephropathy is selected from renal insufficiency, chronic renal failure, chronic glomerulonephritis, IgA nephropathy, diabetic nephropathy and hypertensive nephropathy.
CN2010102008692A 2010-06-09 2010-06-09 Chinese medicinal composition for tonifying kidney and strengthening body Expired - Fee Related CN101856471B (en)

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