CN101744939A - Chinese medicinal herb compound and preparation method with health care effect for preventing mouth disease - Google Patents

Chinese medicinal herb compound and preparation method with health care effect for preventing mouth disease Download PDF

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CN101744939A
CN101744939A CN201010107540A CN201010107540A CN101744939A CN 101744939 A CN101744939 A CN 101744939A CN 201010107540 A CN201010107540 A CN 201010107540A CN 201010107540 A CN201010107540 A CN 201010107540A CN 101744939 A CN101744939 A CN 101744939A
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herba
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chinese medicinal
care effect
radix
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张敏洁
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Abstract

The invention discloses a Chinese medicinal herb compound and preparation method with health care effect for preventing mouth disease; the main drugs in the Chinese medicinal herb compound comprise Polygonum cuspidatum, honeysuckle, Oldenlandia, radix scrophulariae, chrysanthemum, garden balsam stem, asarum, radix angelicae, rattletop, Mentha haplocalyx, pepper and liquorice; the 12 Chinese medicinal herbs have the effects of clearing heat and detoxicating, dispelling wind and promoting diuresis, reducing swelling and easing pain, eliminating unpleasant odor, promoting blood circulation and removing blood stasis, etc, and have obvious effects on preventing mouth diseases and health care. The invneiton is a secret prescription handed down from ancestors, is practiced and applied by a plurality of people, cures a plurality of patients, and is disclosed to the public for propagating Chinese medicinal herb treasures and benefiting mankind.

Description

The herbal composite and the preparation method of prevention oral disease and health-care effect
Technical field
The invention belongs to the herbal composite in a kind of medicine, especially to preventing oral disease and health-care effect that the herbal composite and the preparation method of obvious curative effects are arranged:
Background technology
The complex structure in oral cavity, because temperature, humidity be fit to, and the reason such as remaining of food debris, cause the oral cavity bacterium breeding vigorous.Owing to have a large amount of dental calculuss, tartar etc. in the oral cavity, they contain a large amount of oral cavity bacteriums, are easy to generate volatile sulfide again, cause halitosis, also be easy to generate organic acid such as lactic acid, the long-time decayed tooth that forms easily waits dental disorder, and brings out the gingiva inflammation.If continue bad oral sanitary habit, gingiva will further be damaged, and form periodontitis, red swelling of gingiva, pain, odontoseisis, pyorrhea occur, expose symptoms such as gingiva and halitosis.Along with the state of an illness increases the weight of, alveolar bone makes loosening, the displacement of odontogeny also in regression, forms periodontal pocket; When accompanying infection causes inflammation, occur having an intense pain, symptom such as masticatory atonia, halitosis.Periodontal is not only the first cause that causes the loss of tooth function, influences important organ functions such as heart, lung, kidney especially, causes the important origin cause of formation of the high disease of various mortality rates.Studies show that the enzyme that periodontal bacteria produced can impel thrombus in vivo to form.Periodontal bacteria enters blood, can impel human body to produce a kind of effect and be similar to hematoblastic gluey albumen, forms thrombosis, and occluding vascular causes heart disease and stroke.There is report to claim that the probability of patients with periodontitis generation coronary heart disease and apoplexy is respectively 1.4 times and 2.1 times of the normal person of periodontal.Old people's suffer from an inflammation of the lungs is in close relations with periodontal.Intraoral a large amount of antibacterial can be inhaled into pulmonary, causes pneumonia.Periodontal disease takes place in oral hygiene difference person easily, and its probability that chronic pulmonary infection and pulmonary function reduction take place is 2 times of the good person of oral hygiene.Helicobacter pylori is the pathogenic bacterium of chronic gastritis, gastric ulcer even gastric cancer.In recent years, researcher detects helicobacter pylori in dental plaque and saliva, and the recall rate of helicobacter pylori is higher than the periodontal health healthy person in periodontal disease patient's the bacterial plaque.In addition, periodontal can also cause multiple inflammation as infection focus, as rheumatic or rheumatoid arthritis, glomerulonephritis, iridocyclitis and some dermatosis etc.Oral disease has a strong impact on orthobiosis of people and healthy.
Summary of the invention
The purpose of this invention is to provide a kind of have prevention oral disease and health-care effect, have heat clearing and damp drying, expelling wind and removing dampness, reducing swelling and alleviating pain, removing halitosis, the effect of blood circulation promoting and blood stasis dispelling etc. is used to prevent oral disease and health care that the herbal composite of obvious curative effects is arranged.
Another object of the present invention provides the preparation method of the herbal composite of above-mentioned prevention oral disease and health-care effect.
The present invention is achieved through the following technical solutions above-mentioned purpose:
The invention belongs to a kind of herbal composite with prevention oral disease and health-care effect, the Chinese herbal medicine of being joined part by following weight is that raw material combination is: Rhizoma Polygoni Cuspidati 10-25, Flos Lonicerae 20-35, Herba Hedyotidis Diffusae 10-25, Radix Scrophulariae 10-25, Flos Chrysanthemi 5-15, Herba speranskiae tuberculatae 5-15, Herba Asari 5-15, Radix Angelicae Dahuricae 10-25, Rhizoma Cimicifugae 10-25, Herba Menthae 10-25, Pericarpium Zanthoxyli 5-15, Radix Glycyrrhizae 2-8.
The invention belongs to a kind of herbal composite with prevention oral disease and health-care effect, the Chinese herbal medicine of being joined part by following weight is that raw material combination is: Rhizoma Polygoni Cuspidati 12-20, Flos Lonicerae 22-30, Herba Hedyotidis Diffusae 12-20, Radix Scrophulariae 12-20, Flos Chrysanthemi 6-13, Herba speranskiae tuberculatae 6-13, Herba Asari 6-13, Radix Angelicae Dahuricae 12-20, Rhizoma Cimicifugae 12-20, Herba Menthae 12-18, Pericarpium Zanthoxyli 6-12, Radix Glycyrrhizae 2-6.
The invention belongs to a kind of herbal composite with prevention oral disease and health-care effect, the Chinese herbal medicine of being joined part by following weight is that raw material combination is: Rhizoma Polygoni Cuspidati 16, Flos Lonicerae 25, Herba Hedyotidis Diffusae 16, Radix Scrophulariae 16, Flos Chrysanthemi 6, Herba speranskiae tuberculatae 8, Herba Asari 8, the Radix Angelicae Dahuricae 16, Rhizoma Cimicifugae 15, Herba Menthae 15, Pericarpium Zanthoxyli 5, Radix Glycyrrhizae 2.
Its pharmacology is as follows:
Rhizoma Polygoni Cuspidati: bitter in the mouth, cold in nature, return liver, gallbladder, lung, large intestine channel.Promoting blood circulation to remove blood stasis, clearing away heat-damp and promoting diuresis, detoxifcation cough-relieving, relieving constipation.
Flos Lonicerae: sweet in the mouth, cold in nature, return lung, the heart, stomach warp.Heat-clearing and toxic substances removing, dispelling wind and heat pathogens.Cure mainly the carbuncle furunculosis from the beginning of, red and swollen heat pain, affection due to external wind and heat, epidemic febrile disease from the beginning of, toxic-heat and blood stasis, summer-heat excessive thirst, laryngopharynx swelling and pain.
Herba Hedyotidis Diffusae: bitter in the mouth, light, cold in nature, GUIXIN, liver, spleen channel.Heat-clearing and toxic substances removing, medicinal powder for relieving pain knot, promoting urination to remove dampness.Outstanding kind treatment all kinds inflammation.
Radix Scrophulariae: sweet in the mouth, hardship, salty, cold nature is returned lung, stomach, kidney channel.Clearing away heat and cooling blood, eliminating fire and detoxication, YIN nourishing.Cure mainly: pathogenic warmth is joined the army, the pericardium that caves in, and maculae caused by violent heat pathogen, constipation, hectic fever due to YIN-deficiency chronic cough, conjunctival congestion, pharyngalgia, scrofula, diphtheria, carbuncle sore tumefacting virus are hindered in consumption of YIN caused by febrile disease, crimson tongue excessive thirst, Tianjin.
Flos Chrysanthemi: acrid in the mouth, sweet, hardship, cold nature is returned lung, Liver Channel.Diffusing wind heat clearing away, suppressing the hyperactive liver makes eye bright.Be used for anemopyretic cold, it is dizzy to have a headache, conjunctival congestion and swelling pain, and eyes is dim-sighted.
Herba speranskiae tuberculatae: sweet in the mouth, suffering, warm in nature, return lung, Liver Channel.Expelling wind and removing dampness, the detoxifcation pain relieving.Be used for rheumatic arthritis; Sore swollen toxin is controlled in external.
Herba Asari: acrid in the mouth, warm in nature, return lung, kidney channel.Expelling wind and cold, row water is had one's ideas straightened out.Control air-cooled headache, nasal sinusitis, toothache, phlegm retention cough with dyspnea, rheumatic arthralgia.
The Radix Angelicae Dahuricae: acrid in the mouth, warm in nature, attach to the lung and stomach meridians.Expelling wind and cold, understand things pain-stopping, detumescence and apocenosis, dampness leukorrhagia stopping: control headache, supraorbital bone pain, toothache, nasal sinusitis, cold-damp stomachache, hemorrhoidal hamorrhage anal fistula, leucorrhea with red and white discharge, ulcer sores, skin pruritus due to dryness, scabies.
Rhizoma Cimicifugae: acrid in the mouth, little sweet, cold nature is returned lung, spleen, stomach, large intestine channel.Deliver rash, heat-clearing and toxic substances removing, elevate a turnable ladder yang-energy.Be used for headache due to pathogenic wind-heat, the toothache aphtha, laryngopharynx swelling and pain, measles without adequate eruption, YANG toxin syndrome is sent out speckle, proctoptosis, uterine prolapse.
Herba Menthae: acrid in the mouth, cool in nature, return lung, Liver Channel.Be applicable to that cold, fever, headache, laryngopharynx swelling and pain, lossless, wind-fire acute conjunctivitis, rubella, skin are itched, disease such as colic, dysentery and scrofula, external has slight analgesic effect, is used for neuralgia etc.
Pericarpium Zanthoxyli: acrid in the mouth, warm in nature, return spleen, stomach, kidney channel.Warming middle-JIAO to relieve pain, killing parasites for relieving itching.Be used for coldness and pain in the epigastrium, vomiting is had loose bowels, abdominal pain due to worm stagnation, ascariasis, external treatment eczema scabies.
Radix Glycyrrhizae: sweet in the mouth, property is flat, goes into spleen, the heart, stomach, lung meridian and rather complete urgency, the lung moistening detoxifcation, coordinating the actions of various ingredients in a prescription, moxibustion is with controlling weakness of the spleen and stomach, lack of appetite stomachache, loose stool, overstrain heating, consumptive lung disease cough, cardiopalmus is frightened discharges, give birth to controlling laryngopharynx swelling and pain, peptic ulcer, ulcer sores is separated poison of drug and alimentary toxicosis.
More than 12 the flavor Chinese herbal medicine at " periodontitis; red swelling of gingiva, pain, odontoseisis, pyorrhea occur, expose symptoms such as gingiva and halitosis " of oral pathology because of being caused, and the scheme of formulating with prevention oral disease and health-care effect is with heat-clearing and toxic substances removing, expelling wind and removing dampness pain relieving, removes halitosis, and blood circulation promoting and blood stasis dispelling etc. are main a kind of herbal composite.
The preparation method of herbal composite is as follows: be prepared into collutory, chewing gum and chewable tablet, buccal tablet, product forms such as toothpaste.
The specific embodiment:
Embodiment 1 is prepared into collutory:
The Chinese herbal medicine that described 12 flavor Chinese herbal medicine are joined part by following weight is that material combination is:
Rhizoma Polygoni Cuspidati 10-25, Flos Lonicerae 20-35, Herba Hedyotidis Diffusae 10-25, Radix Scrophulariae 10-25, Flos Chrysanthemi 5-15, Herba speranskiae tuberculatae 5-15, Herba Asari 5-15, Radix Angelicae Dahuricae 10-25, Rhizoma Cimicifugae 10-25, Herba Menthae 10-25, Pericarpium Zanthoxyli 5-15, Radix Glycyrrhizae 2-10.
Preparation method is as follows:
(1) with Flos Chrysanthemi, Herba Menthae joins by weight that part to be ground into coarse powder standby.
(2) all the other 10 flavor medical materials are joined part by weight and went into jar adding five jorum water loggings bubble 2 hours, be fried boiling, use slow fire instead and fry in shallow oil slowly to 30 minutes with vigorous fire; Add (one) standby Flos Chrysanthemi, the Herba Menthae coarse powder, be fried boiling and leached medicinal liquid in one minute, its medicine adds three jorum water again and is fried boiling with vigorous fire in jar, use slow fire instead and fry in shallow oil slowly to 30 minutes and leach medicinal liquid, removes medicinal residues, merge twice medicinal liquid after filtration, the distilled water diluting that adds 20 times of amounts, the sterilization bottling, and make collutory.
Embodiment 2 is prepared into chewing gum and chewable tablet:
The Chinese herbal medicine that 12 flavor Chinese herbal medicine are joined part by following weight is that raw material combination is: Rhizoma Polygoni Cuspidati 12--20, Flos Lonicerae 22--30, Herba Hedyotidis Diffusae 12-20, Radix Scrophulariae 12--20, Flos Chrysanthemi 6-13, Herba speranskiae tuberculatae 6-13, Herba Asari 6-13, Radix Angelicae Dahuricae 12-20, Rhizoma Cimicifugae 12-20, Herba Menthae 12-18, Pericarpium Zanthoxyli 6-12, Radix Glycyrrhizae 2-6.
Preparation method is as follows:
(1) above-mentioned 12 flavor Chinese medicinal herbses is joined part by weight and go into to add in the extraction pot 8 times of 70% ethanol extraction, extract altogether 2 times, each 1 hour, be concentrated into 50 degree Celsius, relative density is the thick paste of 1.30-1.35, and drying under reduced pressure is to 60 degree Celsius, one 0.08Mpa, promptly get extract, the pure one-tenth of extract powder fine powder is standby
(2) vinyl acetate 60 of joining by weight part; esterase 16, polyisobutylene 50, Saccharum Sinensis Roxb. 36 mixes; after fully adding hot milling; add acetyl group methyl ricinoleate 2, calcium carbonate 24 is again after mixing; the extract powder and fine powder that adds gained in (one) item in mixture is joined part 12 by weight; again after fully mixing, send and roll that to prolong machine further mixing, the thickness section promptly gets oral cavity health chewing gum and chewable tablet in accordance with regulations then.
Embodiment 3 is prepared into buccal tablet:
The Chinese herbal medicine that 12 flavor Chinese herbal medicine are joined part by following weight is that raw material combination is: Rhizoma Polygoni Cuspidati 16, Flos Lonicerae 25, Herba Hedyotidis Diffusae 18, Radix Scrophulariae 16, Flos Chrysanthemi 6, Herba speranskiae tuberculatae 8, Herba Asari 8, the Radix Angelicae Dahuricae 16, Rhizoma Cimicifugae 15, Herba Menthae 15, Pericarpium Zanthoxyli 5, Radix Glycyrrhizae 2.
Preparation method is as follows:
(1) above-mentioned 12 flavor Chinese medicinal herbses is joined part by weight and go into to add in the extraction pot 8 times of 70% ethanol extraction, extract altogether 2 times, each 1 hour, be concentrated into 50 degree Celsius, relative density is the thick paste of 1.30-1.35, and drying under reduced pressure is to 60 degree Celsius, a 0.08Mpa, promptly get extract, the pure one-tenth of extract powder fine powder is standby.
(2) preparation method of chewable tablet is made routinely: get and join part lecithin 15 by weight, mannitol 40 is pulverized, add the abundant stirring and evenly mixing sterilization carrying out of adjuvant tablettings such as (one) standby fine powder of gained and polyvinyl pyrrolidone, every contains medicine 0.5 gram per day for adults 2-3 gram consumption.
Embodiment 4 is prepared into toothpaste:
The Chinese herbal medicine that 12 flavor Chinese herbal medicine are joined part by following weight is that raw material combination is: Rhizoma Polygoni Cuspidati 16, Flos Lonicerae 25, Herba Hedyotidis Diffusae 18, Radix Scrophulariae 16, Flos Chrysanthemi 6, Herba speranskiae tuberculatae 8, Herba Asari 8, the Radix Angelicae Dahuricae 16, Rhizoma Cimicifugae 15, Herba Menthae 15, Pericarpium Zanthoxyli 5, Radix Glycyrrhizae 2.
Preparation method is as follows:
(1) above-mentioned 12 flavor Chinese medicinal herbses is joined part by weight and go into to add in the extraction pot 8 times of 70% ethanol extraction, extract altogether 2 times, each 1 hour, be concentrated into 50 degree Celsius, relative density is the thick paste of 1.30-1.35, and drying under reduced pressure is to 60 degree Celsius, a 0.08Mpa, promptly get extract, the pure one-tenth of extract powder fine powder is standby.
(2) carboxymethyl cellulose 0.5 of weight being joined part, hydroxyethyl-cellulose 0.5 after adding weight and joining part water 25 heating for dissolving, adds sodium lauryl sulfate 2 successively, glycerol 15, natural whiting 50, essence 1 and (an one) standby fine powder 10, stir, the cooling back becomes cream, can pack.

Claims (4)

1. one kind has the herbal composite and the preparation method of preventing oral disease and health-care effect, it is characterized in that: the Chinese herbal medicine of being joined part by following weight is that material combination is:
Rhizoma Polygoni Cuspidati 10-25, Flos Lonicerae 20-35, Herba Hedyotidis Diffusae 10-25, Radix Scrophulariae 10-25, Flos Chrysanthemi 5-15, Herba speranskiae tuberculatae 5-15, Herba Asari 5-15, Radix Angelicae Dahuricae 10-25, Rhizoma Cimicifugae 10-25, Herba Menthae 10-25, Pericarpium Zanthoxyli 5-15, Radix Glycyrrhizae 2-8.
2. a kind of herbal composite and preparation method according to claim 1 with prevention oral disease and health-care effect, it is characterized in that: the Chinese herbal medicine of being joined part by following weight is that material combination is:
Rhizoma Polygoni Cuspidati 12-20, Flos Lonicerae 22-30, Herba Hedyotidis Diffusae 12-20, Radix Scrophulariae 12-20, Flos Chrysanthemi 6-13, Herba speranskiae tuberculatae 6-13, Herba Asari 6-13, Radix Angelicae Dahuricae 12-20, Rhizoma Cimicifugae 12-20, Herba Menthae 12-18, Pericarpium Zanthoxyli 6-12, Radix Glycyrrhizae 2-6.
3. a kind of herbal composite and preparation method according to claim 1 with prevention oral disease and health-care effect, it is characterized in that: the Chinese herbal medicine of being joined part by following weight is that material combination is:
Rhizoma Polygoni Cuspidati 16, Flos Lonicerae 25, Herba Hedyotidis Diffusae 16, Radix Scrophulariae 16, Flos Chrysanthemi 6, Herba speranskiae tuberculatae 8, Herba Asari 8, the Radix Angelicae Dahuricae 16, Rhizoma Cimicifugae 15, Herba Menthae 15, Pericarpium Zanthoxyli 5, Radix Glycyrrhizae 2.
4. a kind of herbal composite and preparation method with prevention oral disease and health-care effect according to claim 1, it is characterized in that: described preparation method can be made collutory, chewing gum and chewable tablet, buccal tablet, product systems such as toothpaste type.
CN201010107540A 2010-01-31 2010-01-31 Chinese medicinal herb compound and preparation method with health care effect for preventing mouth disease Pending CN101744939A (en)

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Cited By (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101953903A (en) * 2010-09-13 2011-01-26 杨亚丽 Mouthwash for treating gingivitis of children and preparation method thereof
CN102580035A (en) * 2012-03-15 2012-07-18 步捷 Medicament for treating periodontitis
CN102631448A (en) * 2012-05-10 2012-08-15 石秋华 Medicament for treating periodontitis
CN102657781A (en) * 2012-03-22 2012-09-12 韩继双 Spraying agent for treating periodontitis
CN103893030A (en) * 2012-12-25 2014-07-02 南京恒青楼宇设备有限公司青岛分公司 Chinese herbal medicine mouthwash
CN104434758A (en) * 2014-11-20 2015-03-25 惠州市欧野科技有限公司 Health toothpaste
CN105943437A (en) * 2016-05-31 2016-09-21 安徽皖斛堂生物科技有限公司 Dendrobium officinale toothpaste with antisepsis and anti-inflammation effects
CN106726967A (en) * 2016-12-27 2017-05-31 郑州游爱网络技术有限公司 A kind of function toothpaste for carcinoma of mouth rehabilitation and preparation method thereof
CN106974993A (en) * 2017-04-20 2017-07-25 申翰昭 It is a kind of to treat swelling and aching of gum and clearing heat and detoxicating pharmaceutical composition and preparation method thereof
CN108142944A (en) * 2017-12-29 2018-06-12 河南健特生物科技集团有限公司 For alleviating chewable tablets of endogenous halitosis and preparation method thereof
CN108498353A (en) * 2018-05-25 2018-09-07 佛山市三水区嘉华化学研究院(普通合伙) A kind of tooth-cleaning powder and preparation method thereof
CN110638898A (en) * 2019-10-16 2020-01-03 长沙正源堂生物科技有限公司 Tianshan Qicaiwangzhu capsule

Cited By (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101953903A (en) * 2010-09-13 2011-01-26 杨亚丽 Mouthwash for treating gingivitis of children and preparation method thereof
CN102580035A (en) * 2012-03-15 2012-07-18 步捷 Medicament for treating periodontitis
CN102657781A (en) * 2012-03-22 2012-09-12 韩继双 Spraying agent for treating periodontitis
CN102657781B (en) * 2012-03-22 2013-09-25 韩继双 Spraying agent for treating periodontitis
CN102631448A (en) * 2012-05-10 2012-08-15 石秋华 Medicament for treating periodontitis
CN103893030A (en) * 2012-12-25 2014-07-02 南京恒青楼宇设备有限公司青岛分公司 Chinese herbal medicine mouthwash
CN104434758A (en) * 2014-11-20 2015-03-25 惠州市欧野科技有限公司 Health toothpaste
CN105943437A (en) * 2016-05-31 2016-09-21 安徽皖斛堂生物科技有限公司 Dendrobium officinale toothpaste with antisepsis and anti-inflammation effects
CN106726967A (en) * 2016-12-27 2017-05-31 郑州游爱网络技术有限公司 A kind of function toothpaste for carcinoma of mouth rehabilitation and preparation method thereof
CN106974993A (en) * 2017-04-20 2017-07-25 申翰昭 It is a kind of to treat swelling and aching of gum and clearing heat and detoxicating pharmaceutical composition and preparation method thereof
CN108142944A (en) * 2017-12-29 2018-06-12 河南健特生物科技集团有限公司 For alleviating chewable tablets of endogenous halitosis and preparation method thereof
CN108498353A (en) * 2018-05-25 2018-09-07 佛山市三水区嘉华化学研究院(普通合伙) A kind of tooth-cleaning powder and preparation method thereof
CN110638898A (en) * 2019-10-16 2020-01-03 长沙正源堂生物科技有限公司 Tianshan Qicaiwangzhu capsule

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Application publication date: 20100623