CN101731181A - Method for hatching artemia cysts - Google Patents

Method for hatching artemia cysts Download PDF

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Publication number
CN101731181A
CN101731181A CN200810152907A CN200810152907A CN101731181A CN 101731181 A CN101731181 A CN 101731181A CN 200810152907 A CN200810152907 A CN 200810152907A CN 200810152907 A CN200810152907 A CN 200810152907A CN 101731181 A CN101731181 A CN 101731181A
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Prior art keywords
oxygen
artemia cysts
microcapsules
chemical substance
chemical
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CN200810152907A
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谢坤
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Abstract

The invention relates to a production method of artemia cysts and application thereof, being mainly characterized in that microcapsule dry powder treatment is carried out on oxygen or a chemical drug which can generate the oxygen, thus achieving the effect of generating the oxygen and slowly releasing the oxygen and further promoting high rate of hatchability of the artemia cysts. Microcapsule powder produced by the method can be evenly mixed with the unhatched artemia cysts which are dried, and then can be packaged with the artemia cysts together; and chemicals such as powder and the like are not needed to be additionally packaged, so that safety accidents can be avoided. By adopting the technologies of layered treatment embedding and inlaying macromolecule for treatment, the method leads the chemicals to isolate the oxygen from water molecule without chemical reaction, thus reducing the dosage of chemical substances. Finally, the dosage of the chemical substances can be reduced, and high rate of hatchability of the artemia cysts can be obtained.

Description

A kind of hatching m of artemia cysts
Technical field:
The present invention relates to a kind of microcapsules technology of using, embedding oxygen or the oxygenous microcapsules dry powder a kind of or two or more compounds of energy be used for artemia cysts production, finally reach the incubation rate that improves artemia cysts.
Background technology:
The hatching technique of artemia cysts is very ripe, but everybody usually directly uses peroxide to add seawater to hatch jointly, perhaps directly packs peroxide and artemia cysts is together sold.Because being easy to react with air, water, peroxide causes unnecessary loss and consequence, so carried out this invention.
Summary of the invention: the present invention is that the utilization microcapsules technology is carried out embedding or can oxygenous chemical substance be carried out embedding oxygen under specified temp, finally reaches the purpose that slowly-releasing oxygen improves the artemia ovum hatching rate.
The present invention relates to that artemia cysts must clean earlier described in a kind of claim 1, freezing, dry, weigh; Next is with oxygen or can oxygenous a kind of two kinds of chemical substances be placed on oil item and the laggard row of water Xiang Zhongjing Over emulsfication " microcapsules " processing respectively.
The present invention relates to described in a kind of claim 2, this can possess following feature by oxygenous slowly-releasing " microcapsules ":
---the forced for vitamins layer, this one deck plays the effect that extends the shelf life, and contains the emulsifier of antioxidant and 1≤HLB≤8;
---water-soluble layer, this one deck plays the effect of slowly-releasing, contains the protection composition or contains the material that can react with another kind of material in the oil, the emulsifier of HLB 〉=8;
---the molten layer of oil, this part can contain oxygen or the oxygenous chemical substance of energy;
The present invention relates to a kind of production method and application for the treatment of the new targeted drug of cancer described in a kind of claim 4, it is characterized in that this method finishes according to the following steps:
A: the weighing of medicine
---weighing: can oxygenous chemical substance n, vegetable oil m, emulsifier p (1≤HLB value≤8), emulsifier (HLB value 〉=8) p, take by weighing respectively by weight, wherein n, m, p, be any natural number of 1 to 30;
---the preparation (x) of forced for vitamins breast: be by weight respectively with vitamin e, vitamin c or vitamin c derivative etc.: take by weighing at 0.3: 1, join in the vegetable oil; Adding emulsifier p again in vegetable oil, is 0.5: 1 by the vegetable oil weight ratio, is heated to thawing, mixes.
B: the preparation of layering protection composition
---weighing: with distilled water, starch (or derivative of starch), gelatin (or gelatin substance), pvp, glucose (or monosaccharide material), emulsifier (HLB value 〉=8), the Hybrid Heating dissolving.
C: the preparation of target center medicine
The load weighted chemical substance that can prepare oxygen joined be heated among the A evenly, reach design temperature; Mix with B.
D: the C solution after the dry mixed
---drying: the mixed solution C for preparing is mixed, adopt spray drying process, EAT be 140 ℃ to 180 ℃, temperature of outgoing air be 50 ℃ to 60 ℃, make dry powder; Perhaps fluid-bed drying obtains dry powder.
---finished product: generate the oxygenous microcapsules dry powder of energy that contains n%.
E: microcapsules dry powder that drying is good and dry good artemia cysts mix, stir; Mixed proportion is 1: 50---60.
Use:
Embodiment 1: hydrogen peroxide 10 gram is dissolved in vegetable oil and the emulsifier (1≤HLB value≤8) is heated to emulsification; Water-soluble type skins such as gelatin, starch and emulsifier are heated to dissolving; Above-mentioned two kinds of materials are mixed cooling to 30 degree then rapidly under 80 degree, add clorox, atomized drying under 30 degree: air intake 180 degree, air draft 60 degree are received to such an extent that contain the microcapsules pulvis of hydrogen peroxide and clorox.The microcapsules pulvis that makes mixed thoroughly to pack in artemia cysts according to 1: 50 ratio get final product.
The packed products of above-mentioned embodiment is compared hatching test, and its result is as follows:
Figure G2008101529074D0000031
To directly use peroxide, not use peroxide and the microcapsules method hatching artemia cysts that produces oxygen to compare, its result is as follows:
Chronological classification incubation rate In November, 2005 In December, 2005 In January, 2006 In February, 2006 In March, 2006 In April, 2006 In May, 2006 In June, 2006 In July, 2006 In August, 2006 In September, 2006 In October, 2006
Do not add peroxide ??35% ??35% ??35% ??31% ??32% ??35% ??33% ??40% ??30% ??35% ??39% ??35%
Add peroxide ??70% ??72% ??73% ??75% ??68% ??69% ??60% ??55% ??60% ??50% ??45% ??40%
The microcapsules powder that produces oxygen ??91% ??92% ??95% ??96% ??93% ??94% ??91% ??90% ??92% ??91% ??95% ??90%
Case study on implementation is no longer explained, but does not represent the limitation of this programme.

Claims (5)

1. the production method of an artemia cysts and application is characterized in that:
---adopt oxygen or energy oxygenous microcapsule structure dry powder mixing and purification, dried artemia cysts a kind of or two kinds of chemical substances together to pack.
---artemia cysts need clean, screens, dry, weigh.
2. the method described in the claim 1, its feature:
---this new oxygen microcapsules or the oxygenous chemical substance microcapsule structure medicine of energy are made up of three layer components;
---ground floor: the preparation of forced for vitamins breast (x): with antioxidants such as vitamin e or vitamin c or derivatives thereofs be by weight respectively: take by weighing at 0.3: 1, join in the vegetable oil, vegetable oil and chemical substance weight ratio are 0.5: 1; Adding the emulsifier of 1≤HLB≤8 again in vegetable oil, is 50% by the vegetable oil weight ratio, is heated to thawing, mixes.
---the second layer: the emulsifier of water-soluble layer, starch based or its derivative, monosaccharide and pvp, gelatin class macromolecular substances and HLB 〉=8, can produce chemicals mass-energy uniform dissolution in the aqueous solution of chemical reaction with another kind of chemical substance;
---the 3rd layer: target center medicine oxygen or can oxygenous chemical substance is a kind of be added in vegetable oil or the fatty acid material adds the another kind of chemical substance that can produce chemical reaction with another kind of chemical substance at water-soluble layer.
3. the mixed solution drying at a certain temperature of the mixed solution described in the claim 2: adopt desivac or heating spray drying process, EAT is that 140 to spend to 180 degree, temperature of outgoing air be 40 to spend to 80 degree, makes to contain oxygen or microcapsules dry powder that can oxygenous chemical substance.
---finished product: generate the microcapsules dry powder that contains n% oxygen or the oxygenous chemical substance of energy;
---with above-mentioned solution heat, heating, airtight mixing;
---the above-mentioned solution that mixes is adopted heating spray drying process drying; Perhaps freezing makes dry powder;
---mix the microcapsules dry powder and the dry good artemia cysts that prepare thoroughly together packing jointly;
---can adopt the production technology of large-scale low-costs such as heating high temperature spray-drying method, pressure drying method, fluid-bed drying in the product technology of preparation.
4. described in the claim 3, finished product target center medicine be by a kind of can produce oxygen chemical constitution or all kinds of can with the chemical constitution of another kind of material at the synthetic oxygen of normal temperature; Structural formula such as is expressed as follows at various ways Na 2O 2(at oil layer)+H 2O (at the microcapsules skin)=O 2+ NaOH
SODIUM PERCARBONATE discharges oxygen at oil layer through decomposing behind the slowly-releasing in water
H 2O 2(at oil layer)+NaCLO=NaCL+O 2+ H 2O
CaO 3(at oil layer)+H 2O=O 2+ CaOH
More than just a part of, these peroxide can be preserved very safe in grease.
5. described in the claim 4, dry good microcapsules pulvis peace ratio directly adds in the packing box of packing into after mixing thoroughly in the artemia cysts can sell or directly hatching.
CN200810152907A 2008-11-10 2008-11-10 Method for hatching artemia cysts Pending CN101731181A (en)

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Application Number Priority Date Filing Date Title
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Cited By (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102524196A (en) * 2012-03-23 2012-07-04 天津海友佳音生物科技股份有限公司 Method for improving hatching rate of artemia cysts
CN103210884A (en) * 2013-05-20 2013-07-24 塔里木大学 Method for hatching artemia by utilizing waste water in alkali discharge channel of inland salt and alkali region
CN103563860A (en) * 2013-11-22 2014-02-12 天津海友佳音生物科技股份有限公司 Method for increasing hatching rate of diapause artemia eggs in weak light environment
CN104186431A (en) * 2014-08-20 2014-12-10 天津海友佳音生物科技股份有限公司 High-density artemia breeding method with single-cell protein single-step food chain utilized
CN104273098A (en) * 2014-10-21 2015-01-14 天津海友佳音生物科技股份有限公司 Method for hatching under-diapause brine shrimp eggs in ultraviolet light
CN104488828A (en) * 2014-12-18 2015-04-08 天津海友佳音生物科技股份有限公司 Method for increasing hatching rate of artemia cysts after shelling
CN105815276A (en) * 2015-01-09 2016-08-03 天津丰年水产养殖有限公司 Special culturing salt for increasing hatchability of brine shrimp eggs
CN107347872A (en) * 2017-06-30 2017-11-17 天津海友佳音生物科技股份有限公司 A kind of artemia shelling egg freezing preserves and the formula and method of hatching
CN111246858A (en) * 2017-08-22 2020-06-05 萧湘 Enteric oxygen microcapsule for adjusting intestinal flora and preparation method and application thereof

Cited By (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102524196A (en) * 2012-03-23 2012-07-04 天津海友佳音生物科技股份有限公司 Method for improving hatching rate of artemia cysts
CN102524196B (en) * 2012-03-23 2013-09-04 天津海友佳音生物科技股份有限公司 Method for improving hatching rate of artemia cysts
CN103210884A (en) * 2013-05-20 2013-07-24 塔里木大学 Method for hatching artemia by utilizing waste water in alkali discharge channel of inland salt and alkali region
CN103563860A (en) * 2013-11-22 2014-02-12 天津海友佳音生物科技股份有限公司 Method for increasing hatching rate of diapause artemia eggs in weak light environment
CN104186431A (en) * 2014-08-20 2014-12-10 天津海友佳音生物科技股份有限公司 High-density artemia breeding method with single-cell protein single-step food chain utilized
CN104273098A (en) * 2014-10-21 2015-01-14 天津海友佳音生物科技股份有限公司 Method for hatching under-diapause brine shrimp eggs in ultraviolet light
CN104273098B (en) * 2014-10-21 2016-08-24 天津海友佳音生物科技股份有限公司 A kind of method hatching diapause artemia cysts under ultraviolet light
CN104488828A (en) * 2014-12-18 2015-04-08 天津海友佳音生物科技股份有限公司 Method for increasing hatching rate of artemia cysts after shelling
CN105815276A (en) * 2015-01-09 2016-08-03 天津丰年水产养殖有限公司 Special culturing salt for increasing hatchability of brine shrimp eggs
CN107347872A (en) * 2017-06-30 2017-11-17 天津海友佳音生物科技股份有限公司 A kind of artemia shelling egg freezing preserves and the formula and method of hatching
CN107347872B (en) * 2017-06-30 2021-11-19 天津海友佳音生物科技股份有限公司 Formula and method for freezing, storing and hatching artemia unshelled eggs
CN111246858A (en) * 2017-08-22 2020-06-05 萧湘 Enteric oxygen microcapsule for adjusting intestinal flora and preparation method and application thereof

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Application publication date: 20100616