CN101711231A - 具有(取代苯基)-丙烯醛部分的化合物、它们的衍生物、生物活性及其用途 - Google Patents
具有(取代苯基)-丙烯醛部分的化合物、它们的衍生物、生物活性及其用途 Download PDFInfo
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- CN101711231A CN101711231A CN200880005067A CN200880005067A CN101711231A CN 101711231 A CN101711231 A CN 101711231A CN 200880005067 A CN200880005067 A CN 200880005067A CN 200880005067 A CN200880005067 A CN 200880005067A CN 101711231 A CN101711231 A CN 101711231A
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Abstract
Description
No. | Groups | δ1H | δ13C |
a1 | Ar.=C | 126.83 | |
a2 | Ar.=CH | 7.098(d,J=1.5) | 109.62 |
a3,4,b3,4,c3,c4,d3,4. | Ar.=C(OCH3) | *3.812(s),3.596,3.708,3.968,3.950,3.946,3.857,3.931 | 147.77,147.93,148.96,149.15,149.17,151.25,151.69,151.87 |
a5 | Ar.=CH | 6.878(d,J=8.0) | 110.82 |
a6 | Ar.=CH | 7.167(dd,J=8.0,1.5) | 123.31 |
a11 | =CH | 7.732(d,J=15.5) | 143.25 |
a12 | =CH | 7.017(d,J=15.5) | 116.46 |
a13 | C=O | 182.21 | |
a14 | -CH- | 4.317(s) | 40.75 |
b1 | Ar.=C | 127.84 | |
b2 | Ar.=CH | 6.881(d,J=2.0) | 109.57 |
b5 | Ar.=CH | 6.740(d,J=8.0) | 110.71 |
No. | Groups | δ1H | δ13C |
b6 | Ar.=CH | 7.061(dd,J=8.0,2.0) | 124.09 |
b11 | =CH | 7.681(d,J=15.5) | 145.83 |
b12 | =CH | 6.739(d,J=15.5) | 118.33 |
b13 | C=O | 196.29 | |
c1 | Ar.=C | 126.80 | |
c2 | Ar.=CH | 7.055(d,J=1.5) | 109.80 |
c5 | Ar.=CH | 6.878(d,J=8.5) | 110.82 |
c6 | Ar.=CH | 7.195(dd,J=8.5,1.5) | 123.84 |
c11 | =CH | 7.60(d,J=15.5) | 144.71 |
c12 | =CH | 7.038(d,J=15.5) | 119.03 |
c13 | C=O | 194.59 | |
c14 | -CH- | 4.317(d,J=7.5) | 40.69 |
No. | Groups | δ1H | δ13C |
d1 | Ar.=C | 133.03 | |
d2 | Ar.=CH | 6.653(s) | 111.92 |
d5 | Ar.=CH | 6.740(d,J=8.5) | 110.71 |
d6 | Ar.=CH | 6.676(d,J=8.0) | 120.28 |
d11 | -C- | 68.86 | |
d12 | -CH2 | 3.268(d,J=16.5),3.352(d,J=16.5) | 24.13 |
d13 | C=O | 190.32 | |
d14 | -CH2 | 2.734(d,J=19.5),3.516(dd,J=19.5,7.5) | 37.74 |
a3,4,b3,4,c3,c4,d3,4. | -OCH 3 | 3.596(s),3.708(s),3.812(s),3.857(s),3.946(s),3.931(s),3.950(s),3.968(s) | 55.4055.5955.8755.9456.05 |
Claims (18)
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US87945807P | 2007-01-08 | 2007-01-08 | |
US60/879,458 | 2007-01-08 | ||
PCT/US2008/000285 WO2008085984A1 (en) | 2007-01-08 | 2008-01-08 | Compounds with (substituted phenyl)-propenal moiety, their derivatives, biological activity, and uses thereof |
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US (2) | US8236852B2 (zh) |
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JP (3) | JP2010515685A (zh) |
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CA (1) | CA2674780C (zh) |
DK (1) | DK2104659T3 (zh) |
HK (2) | HK1143802A1 (zh) |
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AU2008205312B2 (en) | 2013-11-21 |
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CA2674780C (en) | 2014-03-11 |
MX2009007345A (es) | 2010-02-22 |
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US20080188557A1 (en) | 2008-08-07 |
EP2993165A2 (en) | 2016-03-09 |
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