CN101704703A - Method for producing high-purity lycopene powder by utilizing plant products - Google Patents
Method for producing high-purity lycopene powder by utilizing plant products Download PDFInfo
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- CN101704703A CN101704703A CN200810132153A CN200810132153A CN101704703A CN 101704703 A CN101704703 A CN 101704703A CN 200810132153 A CN200810132153 A CN 200810132153A CN 200810132153 A CN200810132153 A CN 200810132153A CN 101704703 A CN101704703 A CN 101704703A
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Abstract
The invention discloses a method for producing high-purity lycopene powder by utilizing plant products, belonging to the deep processing field of plant products, and relating to a method for producing high-purity lycopene powder by utilizing natural tomato. The invention provides a method which has relatively simple process, and produces high-purity lycopene powder with high-purity lycopene by utilizing plant products. The method of the invention comprises the following steps: firstly utilizing organic low carbon alcohol and ketone solvent which can mix and dissolve with water to directly mix with pulverized wet tomato skin for extraction, wherein, the ratio of liquid to material is 1:1.5-1:10 and controlling the water content ratio of the total materials after mixing at 5-40%, and the extraction temperature of 50-90 DEG C; the extraction modes can adopt single-pot multiple extraction or multi-pot countercurrent extraction and also can adopt continuous extraction devices to obtain extraction solution, the extraction solution is decompressed and concentrated to directly separate crystal by crystallization or absolute alcohol with the volume being 1-2 is added in the crystallization solution to promote the separation of tomato red crystallization, and the separated lycopene is washed and dried in vacuum to obtain the lycopene powder.
Description
Invention field
The invention belongs to plant prod deep processing field, relate to a kind of method of utilizing natural tomato production high purity lycopene powder.
Background technology
Lyeopene is a kind of carbohydrate, belong to a kind of of carotenoid, have many physiological functions, the discovered in recent years Lyeopene has the antioxidant property stronger than other carotenoid, discover in addition in the human body content of lycopene cross low relevant with some chronic disease and tumour, as prostate cancer, uterus carcinoma, arteriosclerosis etc., also relevant with people's life-span simultaneously, therefore developing Lyeopene is the big problem that present people pay close attention to.
Lyeopene can be from plant prod, as obtaining in tomato, Radix Dauci Sativae, pepper, the plant wet goods.Wherein the content of lycopene in the tomato is the highest.But owing to distribute in the low levels of Lyeopene in these natural products and this compound born of the same parents in certain organ such as chloroplast(id) or chromoblast, the output that leather is got and the product purity of acquisition are very low.
At present, abroad openly the patent of tomato deep processing is more, for example, and EP0844831.CN1251745, US5858700, US5965183 etc.Need material through oven dry or lyophilize before in its disclosed method, extracting Lyeopene, extract with low polar solvent then, higher in its resulting Lyeopene extract owing to resin object content, for the Lyeopene that obtains higher degree also needs complicated aftertreatment technology.But owing to distribute in the low levels of Lyeopene in these natural products and this compound born of the same parents in certain organ such as chloroplast(id) or chromoblast, the output that leather is got and the product purity of acquisition are very low.
Summary of the invention
The present invention is intended to overcome the deficiencies in the prior art part and the high method of utilizing plant prod production high purity lycopene powder of Lyeopene purity that a kind of technology is simple relatively, obtain is provided.
For achieving the above object, the present invention adopts following technical scheme, the present invention includes following steps: at first utilize can be miscible with water organic low-carbon alcohol, the direct mixing with the wet tomato skin of pulverizing of ketone solvent carried out lixiviate, solid-liquid ratio is 1: 1.5-1: 10, the water ratio that mixes the total material in back is controlled at 5%-40%, extraction temperature is 50 ℃-90 ℃, the lixiviate mode adopts single jar of extracted many times or the lixiviate of multiple tank adverse current, also can adopt continuous extraction equipment, the extracting solution that obtains direct crystallization behind concentrating under reduced pressure is separated out crystal, or in the crystallization feed liquid, add the dehydrated alcohol of 1-2 times of volume, promote the red crystallization of tomato to separate out, pass through washing through isolated Lyeopene, vacuum-drying can obtain lycopene powder.
Described organic low-carbon alcohol is methyl alcohol or ethanol, and ketone solvent is acetone or butanone.
Beneficial effect:
The present invention utilizes aqueous low-carbon (LC) polar organic solvent to extract tomato flavor thing in tomato enriched material or the skin slag, utilizes low polar solvent to extract Lyeopene then;
Utilizing method of the present invention can make us be recovered to purity is about 90% crystalline lycopene, reaches as high as 95%, can be conveniently used in medicine, the healthcare products.
Embodiment
Embodiment 1
Acetone mixing carrying out lixiviate with 40 liter 85% of 4 kilograms of tomato powders adding, the water ratio 15% that mixes the total material in back, extraction temperature is 50 ℃, 20 minutes time, the lixiviate mode adopts continuous extraction equipment, vat liquor reflux 25 minutes in 65 ℃ of water-baths, extract secondary, hot pressing leaches extracting solution, isolated extracting solution merges, and has lycopene crystal to separate out behind the concentrating under reduced pressure, adds the dehydrated alcohol of 1.5 times of volumes then in the crystallization feed liquid again, promote the red crystallization of tomato to separate out, isolated Lyeopene can obtain lycopene powder through washing, vacuum-drying.
Embodiment 2
With the methyl alcohol lixiviate of the moisture tomato solid substance of 40 kilograms of bright tomatoes after making beating, separation skin seed, centrifuge dehydration with 15 liters, the water ratio that mixes the total material in back is controlled at 5%-25%, and extraction temperature is 45 ℃, and the lixiviate mode adopts the multiple tank adverse current; Isolated extracting solution reflux 30 minutes in 85 ℃ of water-baths, after hot pressing leaches extracting solution, use 1200 milliliters of sherwood oils reflux 25 minutes in 85 ℃ of water-baths again, extract secondary respectively, isolated extracting solution and extracting solution merging for the first time, have lycopene crystal to separate out behind the concentrating under reduced pressure, isolated Lyeopene can obtain lycopene powder through washing, vacuum-drying.
Embodiment 3
Wet tomato skin after 4 kilograms of pulverizing mixed with 15 liters of butanone carry out lixiviate, the water ratio that mixes the total material in back is controlled at 40%, extraction temperature is 45 ℃, 30 minutes time, the lixiviate mode adopt single jar multiple extraction, isolate for the first time extracting solution reflux 35 minutes in 65 ℃ of water are controlled, after hot pressing leaches extracting solution, use 1200 milliliters of methylene dichloride reflux 45 minutes in 60 ℃ of water-baths again, extract secondary respectively, isolated extracting solution and extracting solution merging for the first time, there is lycopene crystal to separate out behind the concentrating under reduced pressure, the dehydrated alcohol that adds 2 times of volumes then in crystalline mother solution again promotes the red crystallization of tomato to separate out, and isolated Lyeopene is through washing, vacuum-drying can obtain lycopene powder.
Claims (5)
1. utilize the method for plant prod production high purity lycopene powder, it is characterized in that comprising the steps: at first utilizing can be miscible with water organic low-carbon alcohol, the direct mixing with the wet tomato skin of pulverizing of ketone solvent carried out lixiviate, solid-liquid ratio is 1: 1.5-1: 10, the water ratio that mixes the total material in back is controlled at 5%-40%, extraction temperature is 50 ℃-90 ℃, the lixiviate mode adopts single jar of extracted many times or the lixiviate of multiple tank adverse current, also can adopt continuous extraction equipment, the extracting solution that obtains direct crystallization behind concentrating under reduced pressure is separated out crystal, or in the crystallization feed liquid, add the dehydrated alcohol of 1-2 times of volume, promote the red crystallization of tomato to separate out, pass through washing through isolated Lyeopene, vacuum-drying can obtain lycopene powder.
2. the method for utilizing plant prod production high purity lycopene powder according to claim 1 is characterized in that described organic low-carbon alcohol is methyl alcohol or ethanol, and ketone solvent is acetone or butanone.
3. the method for utilizing plant prod production high purity lycopene powder according to claim 1 and 2, it is characterized in that acetone mixing carrying out lixiviate with 40 liter 85% of 4 kilograms of tomato powders adding, the water ratio 15% that mixes the total material in back, extraction temperature is 50 ℃, 20 minutes time, the lixiviate mode adopts continuous extraction equipment, vat liquor reflux 25 minutes in 65 ℃ of water-baths, extract secondary, hot pressing leaches extracting solution, isolated extracting solution merges, there is lycopene crystal to separate out behind the concentrating under reduced pressure, the dehydrated alcohol that adds 1.5 times of volumes then in the crystallization feed liquid again promotes the red crystallization of tomato to separate out, and isolated Lyeopene is through washing, vacuum-drying can obtain lycopene powder.
4. the method for utilizing plant prod production high purity lycopene powder according to claim 1 and 2, it is characterized in that the wet tomato skin after 4 kilograms of pulverizing mixed with 15 liters of butanone and carry out lixiviate, the water ratio that mixes the total material in back is controlled at 40%, extraction temperature is 45 ℃, 30 minutes time, the lixiviate mode adopt single jar multiple extraction, isolate for the first time extracting solution reflux 35 minutes in 65 ℃ of water are controlled, after hot pressing leaches extracting solution, use 1200 milliliters of methylene dichloride reflux 45 minutes in 60 ℃ of water-baths again, extract secondary respectively, isolated extracting solution and extracting solution merging for the first time have lycopene crystal to separate out behind the concentrating under reduced pressure, add the dehydrated alcohol of 2 times of volumes then in crystalline mother solution again, promote the red crystallization of tomato to separate out, isolated Lyeopene is through washing, vacuum-drying can obtain lycopene powder.
5. the method for utilizing plant prod production high purity lycopene powder according to claim 1 and 2, it is characterized in that of the methyl alcohol lixiviate of the moisture tomato solid substance of 40 kilograms of bright tomatoes after making beating, separation skin seed, centrifuge dehydration with 15 liters, the water ratio that mixes the total material in back is controlled at 5%-25%, extraction temperature is 45 ℃, and the lixiviate mode adopts the multiple tank adverse current; Isolated extracting solution reflux 30 minutes in 85 ℃ of water-baths, after hot pressing leaches extracting solution, use 1200 milliliters of sherwood oils reflux 25 minutes in 85 ℃ of water-baths again, extract secondary respectively, isolated extracting solution and extracting solution merging for the first time, have lycopene crystal to separate out behind the concentrating under reduced pressure, isolated Lyeopene can obtain lycopene powder through washing, vacuum-drying.
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| Application Number | Priority Date | Filing Date | Title |
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| CN200810132153A CN101704703A (en) | 2008-07-21 | 2008-07-21 | Method for producing high-purity lycopene powder by utilizing plant products |
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| CN200810132153A CN101704703A (en) | 2008-07-21 | 2008-07-21 | Method for producing high-purity lycopene powder by utilizing plant products |
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Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102660380A (en) * | 2012-05-29 | 2012-09-12 | 刘伯堂 | Method for extracting lycopene oil with dried tomato skin as raw material |
| CN106889421A (en) * | 2017-04-23 | 2017-06-27 | 新疆新植提生物科技有限公司 | The preparation method and its production line of a kind of natural lycopene pulvis |
| CN107106625A (en) * | 2014-11-25 | 2017-08-29 | 利库德有限公司 | The biological activity tomato compositions of lycopene with decrement |
| EP3702412A4 (en) * | 2017-10-25 | 2021-07-28 | Chenguang Biotech Group Co., Ltd. | Method for preparing lycopene crystals with high purity and low harm |
| CN114988979A (en) * | 2019-12-03 | 2022-09-02 | 中国科学院兰州化学物理研究所 | Method for preparing high-purity lycopene by macro-separation |
-
2008
- 2008-07-21 CN CN200810132153A patent/CN101704703A/en active Pending
Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102660380A (en) * | 2012-05-29 | 2012-09-12 | 刘伯堂 | Method for extracting lycopene oil with dried tomato skin as raw material |
| CN107106625A (en) * | 2014-11-25 | 2017-08-29 | 利库德有限公司 | The biological activity tomato compositions of lycopene with decrement |
| CN106889421A (en) * | 2017-04-23 | 2017-06-27 | 新疆新植提生物科技有限公司 | The preparation method and its production line of a kind of natural lycopene pulvis |
| EP3702412A4 (en) * | 2017-10-25 | 2021-07-28 | Chenguang Biotech Group Co., Ltd. | Method for preparing lycopene crystals with high purity and low harm |
| CN114988979A (en) * | 2019-12-03 | 2022-09-02 | 中国科学院兰州化学物理研究所 | Method for preparing high-purity lycopene by macro-separation |
| CN114988979B (en) * | 2019-12-03 | 2024-01-05 | 中国科学院兰州化学物理研究所 | Method for preparing high-purity lycopene by macro separation |
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Open date: 20100512 |