CN101703452A - Disinfectant itching-relieving hand lotion and preparation method thereof - Google Patents
Disinfectant itching-relieving hand lotion and preparation method thereof Download PDFInfo
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- CN101703452A CN101703452A CN200910193910A CN200910193910A CN101703452A CN 101703452 A CN101703452 A CN 101703452A CN 200910193910 A CN200910193910 A CN 200910193910A CN 200910193910 A CN200910193910 A CN 200910193910A CN 101703452 A CN101703452 A CN 101703452A
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- relieving hand
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Abstract
The invention provides a disinfectant itching-relieving hand lotion, which comprises the following raw materials in part by weight: 0.05 to 1 part of bactericide, 0.05 to 1 part of menthol, 5 to 10 parts of humectant, 45 to 65 parts of ethanol, 1 to 18 parts of inorganic base, and 5 to 50 parts of water. A method for preparing the disinfectant itching-relieving hand lotion comprises the following steps: firstly, dissolving the bactericide and the menthol in the ethanol; secondly, adding the humectant and the inorganic base into the mixture in turn; thirdly, mixing the mixture evenly, filtering the mixture, and adding distilled water to a self-filter to a specified amount; and finally, sub-packaging the mixture. The disinfectant itching-relieving hand lotion can disinfect, relieve itching and moisten skin, can effectively prevent the intrusion of bacteria on infected people and articles contacted by hand, and simultaneously can relieve the itching of the skin of a whole body caused by dryness and keep the skin soft and smooth; besides, the disinfectant itching-relieving hand lotion is not needed to be washed by water while being used for disinfecting, relieving the itching and moistening the skin, saves water resources and is more environmentally-friendly.
Description
Technical field
The present invention relates to field of fine chemical, be specifically related to a kind of disinfectant itching-relieving hand lotion and preparation method thereof.
Background technology
Along with the continual renovation of the deterioration of environment for human survival and human medicine at various diseases, the degree of variation of antibacterial, virus is more and more higher, and frequency is more and more faster, and is increasing to the threat of human health.At present at the germ contamination in air and the environment, the active safeguard procedures of taking are few, and are main still by wearing mask, often washing one's hands etc., to reduce or to avoid the infection of antibacterial among air, the crowd.
The effective without comparison sterilization of the general handwashing liquid that uses, and usually not available whenever and wherever possible water source at present cleans, and more can not reach effect antipruritic, Palmitoleic Acid.
Summary of the invention
In order to overcome the defective of present protective articles, the invention provides a kind of protective articles easily, promptly a kind of disinfectant itching-relieving hand lotion is used for sterilization, antipruritic, skin moistening, need not washing simultaneously, conserve water resource, more environmental protection.
To achieve these goals, the present invention adopts following technical scheme:
The invention provides a kind of disinfectant itching-relieving hand lotion, this disinfectant itching-relieving hand lotion contains the following portions by weight proportion raw material:
Antibacterial 0.05-1
Mentholum 0.05-1
Wetting agent 5-10
Ethanol 45-65
Inorganic base 1-18
Water 5-50.
Preferably, described antibacterial is chlorhexidine acetate or hydrogen peroxide.
Preferably, described wetting agent is glycerol or hyaluronic acid.When wetting agent was selected hyaluronic acid, hyaluronic parts by weight were 0.05-0.2.
Preferably, described inorganic base is sodium hydroxide, potassium hydroxide or calcium hydroxide.
The preparation method of above-mentioned disinfectant itching-relieving hand lotion is earlier antibacterial, Mentholum to be dissolved in the ethanol, adds wetting agent and inorganic base then one by one, and mixing filters, and adding distil water is to ormal weight on filter, and packing promptly.
Preferably, antibacterial is chlorhexidine acetate or hydrogen peroxide.
Preferably, wetting agent is glycerol or hyaluronic acid.
Preferably, inorganic base is sodium hydroxide, potassium hydroxide or calcium hydroxide.
But disinfectant itching-relieving hand lotion sterilizing and itch-relieving skin moistening provided by the invention can effectively prevent by the carry disease germs intrusion of the antibacterial in crowd, the article of hands contact, simultaneously, can remove whole skin because of the pruritus due to the drying and keep skin soft and moist.
The specific embodiment
For making the present invention easier to understand,, further set forth the present invention below in conjunction with specific embodiment.Should be understood that these embodiment only to be used to the present invention is described and be not used in to limit the scope of the invention that NM concrete experimental technique in the following example carries out according to the normal experiment method usually.
Embodiment 1:
The disinfectant itching-relieving hand lotion of present embodiment is prepared from by following parts by weight by following raw material:
Chlorhexidine acetate 0.05
Mentholum 0.05
Glycerol 0.01
Ethanol 45
Sodium hydroxide 1
Water 5.
The preparation method of this disinfectant itching-relieving hand lotion is earlier chlorhexidine acetate, Mentholum to be dissolved in the ethanol, glycerol adding and sodium hydroxide one by one then, and mixing filters, and adding distil water is to ormal weight on filter, and packing is promptly.Wherein, chlorhexidine acetate, Mentholum, ethanol, glycerol and sodium hydroxide are by the prescription amount of getting of this disinfectant itching-relieving hand lotion.
In another embodiment, the parts by weight of glycerol are 10.
Embodiment 2:
The invention provides a kind of disinfectant itching-relieving hand lotion, this disinfectant itching-relieving hand lotion contains the following portions by weight proportion raw material:
Hydrogen peroxide 1
Mentholum 1
Hyaluronic acid 0.05
Ethanol 65
Potassium hydroxide 18
Water 50.
The preparation method of this disinfectant itching-relieving hand lotion is earlier hydrogen peroxide, Mentholum to be dissolved in the ethanol, adds hyaluronic acid and potassium hydroxide then one by one, and mixing filters, and adding distil water is to ormal weight on filter, and packing promptly.Wherein, hydrogen peroxide, Mentholum, ethanol, hyaluronic acid and potassium hydroxide are by the prescription amount of getting of this disinfectant itching-relieving hand lotion.
Embodiment 3
The invention provides a kind of disinfectant itching-relieving hand lotion, this disinfectant itching-relieving hand lotion contains the following portions by weight proportion raw material:
Chlorhexidine acetate 0.5
Mentholum 0.5
Hyaluronic acid 0.1
Ethanol 60
Calcium hydroxide 15
Water 25.
The preparation method of this disinfectant itching-relieving hand lotion is earlier chlorhexidine acetate, Mentholum to be dissolved in the ethanol, add hyaluronic acid and calcium hydroxide then one by one, mixing, filter, adding distil water is to ormal weight on filter, packing is promptly. and wherein, chlorhexidine acetate, Mentholum, ethanol, hyaluronic acid and calcium hydroxide are by the prescription amount of getting of this disinfectant itching-relieving hand lotion.
In another embodiment, hyaluronic parts by weight are 0.2.
Embodiment 4: hand skin sterilization test experiments
Respectively doctor, nurse and patient, reviewer, outpatient service toll collector, the pharmaceutical personnel of contagious department, inside and outside section are carried out hand skin sterilization sampling Detection through how tame hospital laboratory, disinfectant itching-relieving hand lotion with embodiment 2 detects experimenter person, detects the clump count of sterilization front and back.Testing result sees Table 1, and by table 1 as seen, total effective rate is 97.48%.See attached list.
Table 1
Embodiment 5: the antipruritic effect test
Use the disinfectant itching-relieving hand lotion in the present embodiment 3 to carry out antipruritic this measure of merit.Get 20 of healthy mices, male and female half and half are divided into 2 groups at random, i.e. matched group and disinfectant itching-relieving hand lotion group, and 10 every group, at mouse carotid back cropping 2 * 2cm
2Back administration.Matched group is coated with 0.2ml 50% ethanol in mice depilation district, and the disinfectant itching-relieving hand lotion group is coated with the 0.2ml disinfectant itching-relieving hand lotion in mice depilation district, is coated with 5 times (0.2ml/ time) altogether.Behind the last coating 10min at mouse carotid back subcutaneous injection 4-AP 1mg/kg, observe and record 10min in mice lick the body number of times (licking precursor reactant be mice and occur turning one's head repeatedly licking the behavior of both sides nape portion, lick body continuously to minibreak occurring with mice, work is licked body and is calculated for 1 time), calculate the reaction suppression ratio, and take statistics is handled.Suppression ratio=(matched group is licked body number of times-administration group and licked the body number of times)/matched group is licked body number of times * 100%.
The allergy that table 2 causes 4-AP for disinfectant itching-relieving hand lotion causes the influence (x ± s) of the reaction of itching.
Table 2
| Group | Number of animals (only) | Dosage (ml) | Every 10min mice licks the body number of times | Suppression ratio (%) |
| Matched group | ??10 | ??0.2 | ??40.20±18.62 | |
| The disinfectant itching-relieving hand lotion group | ??10 | ??0.2 | ??16.74±7.79 ** | ??69.35％ |
Annotate: * * represents to compare with matched group, and there is significant difference P＜0.01
By table 2 as seen, used disinfectant itching-relieving hand lotion has tangible itching-relieving efficacies.
Last institute should be noted that; above embodiment is only in order to illustrate technical scheme of the present invention but not limiting the scope of the invention; although the present invention has been done detailed description with reference to preferred embodiment; those of ordinary skill in the art is to be understood that; can make amendment or be equal to replacement technical scheme of the present invention, and not break away from the essence and the scope of technical solution of the present invention.
Claims (9)
1. a disinfectant itching-relieving hand lotion is characterized in that, contains the following portions by weight proportion raw material:
Antibacterial 0.05-1
Mentholum 0.05-1
Wetting agent 0.01-10
Ethanol 45-65
Inorganic base 1-18
Water 5-50.
2. disinfectant itching-relieving hand lotion according to claim 1 is characterized in that, described antibacterial is chlorhexidine acetate or hydrogen peroxide.
3. disinfectant itching-relieving hand lotion according to claim 1 is characterized in that, described wetting agent is glycerol or hyaluronic acid.
4. disinfectant itching-relieving hand lotion according to claim 3 is characterized in that, described hyaluronic parts by weight are 0.05-0.2.
5. disinfectant itching-relieving hand lotion according to claim 1 is characterized in that, described inorganic base is sodium hydroxide, potassium hydroxide or calcium hydroxide.
6. the preparation method of the described disinfectant itching-relieving hand lotion of claim 1 is characterized in that earlier antibacterial, Mentholum being dissolved in the ethanol, adds wetting agent and inorganic base then one by one, and mixing filters, and adding distil water is to ormal weight on filter, and packing promptly.
7. preparation method according to claim 6 is characterized in that, described antibacterial is chlorhexidine acetate or hydrogen peroxide.
8. preparation method according to claim 6 is characterized in that, described wetting agent is glycerol or hyaluronic acid.
9. preparation method according to claim 6 is characterized in that, described inorganic base is sodium hydroxide, potassium hydroxide or calcium hydroxide.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN200910193910A CN101703452A (en) | 2009-11-16 | 2009-11-16 | Disinfectant itching-relieving hand lotion and preparation method thereof |
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| CN200910193910A CN101703452A (en) | 2009-11-16 | 2009-11-16 | Disinfectant itching-relieving hand lotion and preparation method thereof |
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| CN200910193910A Pending CN101703452A (en) | 2009-11-16 | 2009-11-16 | Disinfectant itching-relieving hand lotion and preparation method thereof |
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2011149355A1 (en) | 2010-05-28 | 2011-12-01 | Hfp Ingrediënts B.V. | Decontamination of contaminated food products |
| CN102579282A (en) * | 2012-03-08 | 2012-07-18 | 义乌市庆鹏化妆品有限公司 | Itching-relieving and moisturizing body wash |
| CN107789270A (en) * | 2017-10-26 | 2018-03-13 | 伍海文 | A kind of hand protection liquid of quick processing Marjoram Extract |
-
2009
- 2009-11-16 CN CN200910193910A patent/CN101703452A/en active Pending
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2011149355A1 (en) | 2010-05-28 | 2011-12-01 | Hfp Ingrediënts B.V. | Decontamination of contaminated food products |
| CN102579282A (en) * | 2012-03-08 | 2012-07-18 | 义乌市庆鹏化妆品有限公司 | Itching-relieving and moisturizing body wash |
| CN102579282B (en) * | 2012-03-08 | 2013-07-31 | 义乌市庆鹏化妆品有限公司 | Itching-relieving and moisturizing body wash |
| CN107789270A (en) * | 2017-10-26 | 2018-03-13 | 伍海文 | A kind of hand protection liquid of quick processing Marjoram Extract |
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Application publication date: 20100512 |