CN101543533A - Medicament for treating leukemia - Google Patents

Abstract

The invention discloses a medicament for treating leukemia, which is prepared by mixing astragalus root, radix codonopsitis, angelica, radix bupleuri, field thistle, herba scutellariae barbatae, rhizoma atractylodis macrocephalae, tuckahoe, honey-fried licorice root, safflower, kelp, yam, mistletoe, aloe, cinnamon, cassia twig, atractylis ovata and roasted toad. The medicament has supernatural therapeutic effect on the leukemia, and has the characteristics of less dosage, high cure rate, short treatment time, economization, and no damage to normal cells.

Description

The leukemic medicine of a kind of treatment

Technical field

The invention belongs to the field of Chinese medicines, especially relate to the leukemic medicine of a kind of treatment.

Background technology

Leukemia is one of difficult disease, and its clinical manifestation is leukocytic malignant tumor, pathology be in the bone marrow certain type immaturity and paramorph hemocyte uncontrolledly hypertrophy, soak into other tissue and enter in the blood.Treatment leukemia majority adopts chemotherapy at present, chemotherapeutic effect just is to kill in early days juvenile cell in the blood, but spent the chemotherapy phase, also juvenile cell can occur in the blood, also needed chemotherapy again, chemotherapy repeatedly not only expends patient's great effort and financial resources, and chemotherapy all can cause huge infringement to the immune system of body at every turn, also can cause serious liver, spleen, lymphadenectasis, symptoms such as ascites, heart failure, make the state of an illness more complicated refractory that becomes, whole entail dangers to life.As seen, chemotherapy does not reach the leukemic purpose of thorough radical cure at all, can only play the purpose that alleviates the patient suffering and prolong patient's life in a short time.And can effect a radical cure not only surgery cost costliness of leukemic marrow transplant techniques may, and to find the bone marrow of same type extremely difficult, so more patient can not accept this Therapeutic Method.

Summary of the invention

Technical problem to be solved by this invention provides a kind of short treating period, cure rate height, the leukemic medicine of treatment cheap and taking convenience.

In order to solve the problems of the technologies described above, the invention provides the leukemic medicine of a kind of treatment, it is characterized in that it mainly is to be made by following raw materials in weight portion medicine:

Radix Astragali Preparata 25-100 Radix Codonopsis 25-100 Radix Angelicae Sinensis 10-40 Radix Bupleuri 5-20

Herba Cirsii 12-50 Herba Scutellariae Barbatae 12-50 Rhizoma Atractylodis Macrocephalae (parched) 10-40 Poria 15-60

Radix Glycyrrhizae Preparata 8-30 Flos Carthami 8-30

Preferably: Radix Astragali Preparata 50 Radix Codonopsis 50 Radix Angelicae Sinensis 20 Radix Bupleuri 10 Herba Cirsiis 25

Herba Scutellariae Barbatae 25 Rhizoma Atractylodis Macrocephalae (parched)s 20 Poria 30 Radix Glycyrrhizae Preparatas 15 Flos Carthamis 15

Each ingredients weight parts proportioning of medicine of the present invention can also be

Radix Astragali Preparata 25-100 Radix Codonopsis 25-100 Radix Angelicae Sinensis 10-40 Radix Bupleuri 5-20

Herba Cirsii 12-50 Herba Scutellariae Barbatae 12-50 Rhizoma Atractylodis Macrocephalae (parched) 10-40 Poria 15-60

Radix Glycyrrhizae Preparata 8-30 Flos Carthami 8-30 Thallus Laminariae (Thallus Eckloniae) 8-30 Rhizoma Dioscoreae 15-60

Herba Taxilli 15-60 Aloe 10-40

Preferably: Radix Astragali Preparata 50 Radix Codonopsis 50 Radix Angelicae Sinensis 20 Radix Bupleuri 10 Herba Cirsiis 25

Herba Scutellariae Barbatae 25 Rhizoma Atractylodis Macrocephalae (parched)s 20 Poria 30 Radix Glycyrrhizae Preparatas 15 Flos Carthamis 15

Thallus Laminariae (Thallus Eckloniae) 15 Rhizoma Dioscoreaes 30 Herba Taxillis 30 Aloes 20

The medicine of the present invention further weight portion proportioning of each component is

Radix Astragali Preparata 25-100 Radix Codonopsis 25-100 Radix Angelicae Sinensis 10-40 Radix Bupleuri 5-20

Herba Cirsii 12-50 Herba Scutellariae Barbatae 12-50 Rhizoma Atractylodis Macrocephalae (parched) 10-40 Poria 15-60

Radix Glycyrrhizae Preparata 8-30 Flos Carthami 8-30 Thallus Laminariae (Thallus Eckloniae) 8-30 Rhizoma Dioscoreae 15-60

Herba Taxilli 15-60 Aloe 10-40 Cortex Cinnamomi 8-30 Ramulus Cinnamomi 5-20

Rhizoma Curcumae Longae 8-30 Venenum Bufonis (processed) 5-20

Preferably: Radix Astragali Preparata 50 Radix Codonopsis 50 Radix Angelicae Sinensis 20 Radix Bupleuri 10 Herba Cirsiis 25

Herba Scutellariae Barbatae 25 Rhizoma Atractylodis Macrocephalae (parched)s 20 Poria 30 Radix Glycyrrhizae Preparatas 15 Flos Carthamis 15

Thallus Laminariae (Thallus Eckloniae) 15 Rhizoma Dioscoreaes 30 Herba Taxillis 30 Aloes 20 Cortex Cinnamomis 15

Ramulus Cinnamomi 10 Rhizoma Curcumae Longaes 15 Venenum Bufonis (processed) 10

Medicament selection Radix Astragali Preparata of the present invention is because the sweet tepor of Radix Astragali Preparata nature and flavor is returned the spleen lung meridian, tonifying Qi and lifting yang, and benefit is defended consolidating superficial resistance, promoting pus discharge and tissue regeneration strengthening, inducing diuresis to remove edema.Radix Astragali Preparata can spleen reinforcing the gas of lung, the enhancing human body immunity function protects the liver, heart tonifying, diuresis, blood sugar regulation, anti-radiation electric injury.Select Radix Codonopsis to be because the Radix Codonopsis nature and flavor are sweet flat, return the spleen lung meridian, invigorating the spleen and replenishing QI is promoted the production of body fluid and is nourished blood.Has shock, resisting fatigue, radioprotective, antiallergic, antitumaous effect.Can interrenal system stimulation, improve the stress ability, can strengthen the gonad function, the effect of the sex gland hormones of promotion sample is arranged, but blood sugar lowering in addition promotes protein RNA, DNA biosynthesis, the cholesterol regulating metabolism promotes the hemopoietic system function.Select for use Radix Angelicae Sinensis to be because Radix Angelicae Sinensis nature and flavor Gan Xinwen returns liver heart spleen channel, the hemopoietic reinforcing the heart, hold up empty benefit to decrease, the removing blood stasis tissue regeneration promoting contains Radix Angelicae Sinensis polysaccharide, vitamin, aminoacid, succinic acid, have blood fat reducing, protect the liver, antiinflammatory, anti-hypoxia, Antiradiation injury, suppress tumor and antibacterial action.Select for use Radix Bupleuri to be because Radix Bupleuri nature and flavor toil is slightly cold GUIXIN envelope liver three warmers gallbladder meridian.Its effect is a reducing fever by reconciliation, dispersing the stagnated live-QI to relieve the stagnation of QI, elevate a turnable ladder yang-energy.Pathogenic fire reducing effects such as the heating for the treatment of the liver gallbladder, flu.Selecting Herba Cirsii for use is that the GUIXIN Liver Channel has clearing away heat from blood because of the sweet cold of Herba Cirsii nature and flavor, detumescence poison, blood stasis removing and clots absorbing effect.Subduing inflammation, sore also have bacteriostasis.Select for use Herba Scutellariae Barbatae to be because Herba Scutellariae Barbatae is because the Herba Scutellariae Barbatae nature and flavor are hot little bitter cool, return lung liver taste large intestine channel.Relieve internal heat anticancer, dispersing swelling and dissipating binds, the hemostasis of becoming silted up of dispelling are used for the long-pending poison of carcinoma, dispersing swelling and dissipating binds, the swollen knot of carbuncle skin ulcer.Above-mentioned Six-element medicine is a monarch drug, mainly plays physical strength reinforcing, increases body immunity, has only physical strength reinforcing and immunity, and body just can have resistance against diseases, resistance, antagonism virus.Selecting Rhizoma Atractylodis Macrocephalae (parched), Poria, Radix Glycyrrhizae Preparata, Flos Carthami four flavor ministerial drugs for use is because Rhizoma Atractylodis Macrocephalae (parched) is because the some temperature of Rhizoma Atractylodis Macrocephalae (parched) nature and flavor are returned the taste warp, air making-up and spleen enlivening, and the dampness diuretic is used for deficiency of the spleen causing weakness of QI, dysfunction of the spleen in transportation and transformation.The Poria slightly sweet flavor is flat, GUIXIN spleen kidney channel, promoting diuresis to eliminate damp pathogen, spleen-benefiting mind-tranquilizing.Be used for spleen deficiency, cardiopalmus, insomnia.The Radix Glycyrrhizae Preparata nature and flavor are sweet flat, GUIXIN lung taste warp.Invigorating the spleen and replenishing QI, nourishing the lung to arrest cough, relieving spasm to stop pain, relieving cough and asthma is used for weakness of the spleen and stomach, deficiency of QI in middle-JIAO, shortness of breath and fatigue, anorexia and loose stool.The Flos Carthami property and flavor of peppery and warm, the GUIXIN Liver Channel, blood circulation promoting and blood stasis dispelling leads to the regulating menstruation arteries and veins, has the merit of removing pathogenic heat from blood and toxic substance from the body again concurrently.Be used for stagnation of blood stasis, hematogenous blockage.This four flavors ministerial drug air making-up and spleen enlivening, removing pathogenic heat from blood and toxic substance from the body, auxiliary monarch drug clearing away heat from blood, the detumescence poison, the sore that disappears, make drug effect confiscate performance, discharge, promote effective ingredient to absorb, digest.

In order to reach better therapeutic, medicine of the present invention also makes up with Thallus Laminariae (Thallus Eckloniae), Rhizoma Dioscoreae, Herba Taxilli, Aloe four flavor adjuvant drugs, and this is because the Thallus Laminariae (Thallus Eckloniae) nature and flavor are salty-cold, returns liver stomach kidney channel, eliminating phlegm and softening indurated mass, diuretic.Be used for diseases such as goiter, scrofula.The Rhizoma Dioscoreae nature and flavor are sweet flat, return spleen lung kidney channel.Supplementing QI and nourishing YIN, spleen reinforcing lung kidney.Be used for deficiency of the spleen causing weakness of QI, anorexia and loose stool or have loose bowels.The Herba Taxilli nature and flavor are bitter flat, return the Liver and kidney warp, wind-damp dispelling, and invigorating the liver and kidney, bone and muscle strengthening is used for rheumatic arthralgia, soreness of waist and knee joint, the Shujin network.Suppress virus.Aloe nature and flavor bitter cold is returned the liver large intestine channel.Rush down liver heat removing parasite killing down.The energy relieving constipation by purgation, kind clearing away liver-fire.The common assistant of the above five tastes helps the monarch and his subjects' product invigorating the spleen and replenishing QI, the effect of promoting the production of body fluid and nourishing blood.

In order to obtain optimum curative effect, medicine of the present invention also can add Cortex Cinnamomi, Ramulus Cinnamomi, Rhizoma Curcumae Longae, Venenum Bufonis (processed) on the basis of said medicine, and this is because Cortex Cinnamomi property acrid-sweet flavor heat is returned kidney spleen conscience warp.It is supporing yang to mend fire, dispersing cold for relieving pain, promoting the flow of QI-blood by warming the meridian.Be used for arthralgia due to cold-dampnes, QI and blood deficiency and coldness, carbuncle difficulty in discharging of pus.Ramulus Cinnamomi acrid-sweet flavor temperature, GUIXIN lung urinary bladder channel, relieving the exterior syndrome by diaphoresis, warming the meridian for promoting the flow of YANG QI.Be used for anemofrigid-damp arthralgia, heart deficiency of spleen-YANG, yang-energy is not all right.Rhizoma Curcumae Longae property acrid-sweet flavor temperature is returned the liver spleen channel, removing blood stasis circulation of qi promoting, inducing menstruation to relieve menalgia.Moxibustion Venenum Bufonis acrid-sweet flavor temperature, poisonous, removing toxic substances and promoting subsidence of swelling, pain relieving is had one's ideas straightened out.Be used for the carbuncle furuncle, can control the malignant boil toxic swelling, ward off dirty evil again, the epidemic disease toxic action.Have that central is breathed excitation and calmness, antiinflammatory, eliminated the phlegm, antitumor action, scrofula, scrofula, infantile malnutrition, caking, malignant boil, broken tumor, malignant tumor, leukemia are had better curative effect.Above-mentioned four flavor messenger drug play the effect of equilibrium between yin and yang, help the monarch and his subjects' adjuvant drug homergy, thereby reach the purpose of treatment, more than 18 the flavor medicinal medicine ingenious, rationally, compatibility is superior, has one's own knack, it can be given full play to the pharmic function factor and effective ingredient and discharge, and no matter is that viral infection or bacterial infection are all effective.

This has magical especially curative effect with bright medicine to leukemia, and its maximum characteristics are that medication is few, the cure rate height, and treatment time is short, saves money, and does not damage normal cell.

Therapeutic effect below by model case explanation medicine of the present invention

Case 1: Guo XX, the man, 9 years old, spring nineteen ninety was suffered from acute leukemia, pale complexion, slow movement, serious anemia.Chemical examination: leukocyte about 30,000, myasthenia of limbs through with this medicine 18 days, chemically examines that all are normal, cures not have and recurs.

Case 2: Liu Lili, the woman, 6 years old, suffered from acute leukemia, chemical examination in 1991: the full visual field of leukocyte, brothers are unable, pale complexion, hematuria, serious anemia, through with this medicine after 21 days all symptoms disappear entirely, chemically examine that all are normal, healing.

Case 3: open XX, woman, 25 years old, the headache of usual panesthesia, dizzy, tinnitus, general weakness is found anemia on inspection, heating, hemorrhage, tongue is white, symptoms such as weak pulse, check to show that myelosis is active, G:E=6.5:1, grain system, red be that hypertrophy is subjected to press down, account for 13%, 2% respectively, lymphocyte accounts for 48%, 54 of megalokaryocytes, and leukocyte count 3.70 in the blood routine examination, neutrophilic granulocyte is several 0.70, erythrocyte 1.38, and platelet 175 is diagnosed as acute lymphoblastic leukemia.Oral medicine of the present invention is after one month, and bleeding weakens, on inspection G:E=2.5: 1, lymphocyte accounts for 28%, 16 of megalokaryocytes, take one month after, symptom such as anemia, hemorrhage, osteodynia has obtained obvious control, G:E=1.35:1 on inspection, lymphocyte accounts for 23%, and grain system accounts for 54%, and red system accounts for 26%, 8 of megalokaryocytes, the leukocyte differential count result is roughly normal.

Embodiment 1

Radix Astragali Preparata 50 gram Radix Codonopsis 50 gram Radix Angelicae Sinensis 20 gram Radix Bupleuri 10 gram Herba Cirsiis 25 grams

Herba Scutellariae Barbatae 25 gram Rhizoma Atractylodis Macrocephalae (parched)s 20 gram Poria 30 gram Radix Glycyrrhizae Preparatas 15 gram Flos Carthamis 15 grams

The 80-100 mesh sieve was pulverized in above-mentioned ten flavor crude drug processing, adorned 1000 capsules, 2 of heavy patient's oral meals, each one of hypopathia people, be a course of treatment at twice, one month every day, can cure a course of treatment.

Animal experiment: infecting mouse, inappetence, the mental status is not good, and is drowsiness, anemia, leukocyte increases, movable few, each 2 through medicine feed, every day 2 times, administration is after 3 days, and appetite is good, weight increase, active, resistance obviously strengthens, and immunity improves, and laboratory leukocyte obviously improves.

Embodiment 2

Radix Astragali Preparata 50 gram Radix Codonopsis 50 gram Radix Angelicae Sinensis 20 gram Radix Bupleuri 10 gram Herba Cirsiis 25 grams

Herba Scutellariae Barbatae 25 gram Rhizoma Atractylodis Macrocephalae (parched)s 20 gram Poria 30 gram Radix Glycyrrhizae Preparatas 15 gram Flos Carthamis 15 grams

Thallus Laminariae (Thallus Eckloniae) 15 Keshan medicines 30 gram Herba Taxillis 30 gram Aloes 20 grams

Method by embodiment 1 prepares capsule, and a capsules medicated powder is poured in 20 milliliters of aerosol apparatus, after the dilution evenly of 10 ml distilled waters, the oral cavity larynx is sprayed.

Animal experiment: infecting mouse heating, fever, pain relieving, calmness, redness are had obvious curative effects, and being festered in the mice oral cavity has significant curative effect.

Embodiment 3

Radix Astragali Preparata 50 gram Radix Codonopsis 50 gram Radix Angelicae Sinensis 20 gram Radix Bupleuri 10 gram Herba Cirsiis 25 grams

Herba Scutellariae Barbatae 25 gram Rhizoma Atractylodis Macrocephalae (parched)s 20 gram Poria 30 gram Radix Glycyrrhizae Preparatas 15 gram Flos Carthamis 15 grams

Thallus Laminariae (Thallus Eckloniae) 15 Keshan medicines 30 gram Herba Taxillis 30 gram Aloes 20 gram Cortex Cinnamomis 15 grams

Ramulus Cinnamomi 10 gram Rhizoma Curcumae Longaes 15 gram Venenum Bufonis (processed) 10 grams

Method by embodiment 1 prepares capsule, with a capsules medicated powder and 2-3 gram vaseline oil mix homogeneously, make ointment suppository contained, nasal mucosa medicine administration.This method administration mainly is that action effect is slow to old people, oral, the difficult patient that sprays, but lasting medicine.

Animal experiment: improved fully in the symptom 5-7 of mouse leukemia days, and chemically examined after 18-21 days, granulocyte, erythrocyte, lymphocyte are all normal, perusal, and sick Mus is the same with normal mice, without any difference.

Claims (6)

1, the leukemic medicine of a kind of treatment is characterized in that it mainly is to be made by following raw materials in weight portion medicine:

Radix Astragali Preparata 25-100 Radix Codonopsis 25-100 Radix Angelicae Sinensis 10-40 Radix Bupleuri 5-20

Herba Cirsii 12-50 Herba Scutellariae Barbatae 12-50 Rhizoma Atractylodis Macrocephalae (parched) 10-40 Poria 15-60

Radix Glycyrrhizae Preparata 8-30 Flos Carthami 8-30.

2, the leukemic medicine of a kind of treatment according to claim 1 is characterized in that the weight portion consumption of each raw material is:

Radix Astragali Preparata 50 Radix Codonopsis 50 Radix Angelicae Sinensis 20 Radix Bupleuri 10 Herba Cirsiis 25

Herba Scutellariae Barbatae 25 Rhizoma Atractylodis Macrocephalae (parched)s 20 Poria 30 Radix Glycyrrhizae Preparatas 15 Flos Carthamis 15.

3, the leukemic medicine of a kind of treatment according to claim 1 is characterized in that crude drug also has:

Thallus Laminariae (Thallus Eckloniae) 8-30 weight portion Rhizoma Dioscoreae 15-60 weight portion Herba Taxilli 15-60 weight portion

Aloe 10-40 weight portion.

4, the leukemic medicine of a kind of treatment according to claim 3 is characterized in that the weight portion consumption of each component is:

Radix Astragali Preparata 50 Radix Codonopsis 50 Radix Angelicae Sinensis 20 Radix Bupleuri 10 Herba Cirsiis 25

Herba Scutellariae Barbatae 25 Rhizoma Atractylodis Macrocephalae (parched)s 20 Poria 30 Radix Glycyrrhizae Preparatas 15 Flos Carthamis 15

Thallus Laminariae (Thallus Eckloniae) 15 Rhizoma Dioscoreaes 30 Herba Taxillis 30 Aloes 20.

5, the leukemic medicine of a kind of treatment according to claim 3 is characterized in that crude drug also has:

Cortex Cinnamomi 8-30 weight portion Ramulus Cinnamomi 5-20 weight portion Rhizoma Curcumae Longae 8-30 weight portion

Venenum Bufonis (processed) 5-20 weight portion.

6, the leukemic medicine of a kind of treatment according to claim 5 is characterized in that the weight portion consumption of each component is:

Radix Astragali Preparata 50 Radix Codonopsis 50 Radix Angelicae Sinensis 20 Radix Bupleuri 10 Herba Cirsiis 25

Herba Scutellariae Barbatae 25 Rhizoma Atractylodis Macrocephalae (parched)s 20 Poria 30 Radix Glycyrrhizae Preparatas 15 Flos Carthamis 15

Thallus Laminariae (Thallus Eckloniae) 15 Rhizoma Dioscoreaes 30 Herba Taxillis 30 Aloes 20 Cortex Cinnamomis 15

Ramulus Cinnamomi 10 Rhizoma Curcumae Longaes 15 Venenum Bufonis (processed) 10.