CN101528251B - 用于预防和治疗糖尿病性周围神经病变的含有g-csf的治疗剂 - Google Patents
用于预防和治疗糖尿病性周围神经病变的含有g-csf的治疗剂 Download PDFInfo
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Abstract
Description
分类 | 0天 | 28天 |
对照组(生理盐水给药) | 32.63±1.6m/s | 35.58±0.9m/s |
测试组(G-CSF给药) | 31.93±1.5m/s | 40.68±1.9m/s |
分类 | 0天 | 28天 |
对照组(生理盐水给药) | 3.6±0.8s | 5.3±0.4s |
测试组(G-CSF给药) | 3.8±0.5s | 10.5±2.9s |
分类 | 性别 | 年龄 | 身高 | 体重 | 血糖 | 诊断的疾病 |
病例1 | 男 | 78 | 165 | 60 | 132 | 糖尿病性周围神经病变,冠心病(CAD) |
病例2 | 女 | 59 | 168 | 79 | 102 | 糖尿病性周围神经病变,急性心肌梗死(AMI) |
病例3 | 男 | 65 | 166 | 66 | 78 | 糖尿病性周围神经病变,急性心肌梗死(AMI) |
病例4 | 女 | 61 | 160 | 65 | 161 | 糖尿病性周围神经病变,急性心肌梗死(AMI) |
病例5 | 男 | 65 | 164 | 64 | 141 | 糖尿病性周围神经病变,急性心肌梗死(AMI) |
分类 | 0天 | 7天 | 15天 | 30天 | 60天 | 90天 |
病例1 | 32.4 | 34.1 | 36.7 | 38.3 | 40.1 | 40.8 |
病例2 | 31.6 | 32.5 | 34.1 | 40.1 | 41.3 | 42.6 |
病例3 | 34.3 | 34.2 | 35.8 | 39.1 | 39.7 | 39.8 |
病例4 | 30.8 | 32.9 | 33.7 | 39.2 | 41.6 | 41.2 |
病例5 | 35.2 | 34.8 | 36.3 | 42.8 | 42.7 | 41.2 |
Claims (3)
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KR1020060105684 | 2006-10-30 | ||
KR10-2006-0105684 | 2006-10-30 | ||
KR1020060105684A KR100812274B1 (ko) | 2006-10-30 | 2006-10-30 | G-csf를 유효성분으로 하는 당뇨성 말초신경병 예방 및치료제 |
PCT/KR2007/005353 WO2008054098A1 (en) | 2006-10-30 | 2007-10-29 | Agent comprising g-csf for prevention and treatment of diabetic peripheral neuropathy |
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CN101528251A CN101528251A (zh) | 2009-09-09 |
CN101528251B true CN101528251B (zh) | 2013-03-06 |
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US (2) | US20100048869A1 (zh) |
EP (1) | EP2077852B1 (zh) |
JP (1) | JP5416589B2 (zh) |
KR (1) | KR100812274B1 (zh) |
CN (1) | CN101528251B (zh) |
AU (1) | AU2007314854B2 (zh) |
BR (1) | BRPI0718099A2 (zh) |
CA (1) | CA2667178C (zh) |
ES (1) | ES2448837T3 (zh) |
HK (1) | HK1132461A1 (zh) |
MX (1) | MX2009004646A (zh) |
NZ (1) | NZ576498A (zh) |
PT (1) | PT2077852E (zh) |
RU (1) | RU2448726C2 (zh) |
UA (1) | UA93581C2 (zh) |
WO (1) | WO2008054098A1 (zh) |
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KR100908628B1 (ko) * | 2008-03-21 | 2009-07-21 | 한양대학교 산학협력단 | G-csf를 유효성분으로 하는 외상성 말초신경 손상 치료용 조성물 |
KR20100020125A (ko) * | 2008-08-12 | 2010-02-22 | 한양대학교 산학협력단 | G-csf를 유효성분으로 하는 신경병증성 통증 예방 또는치료제 |
KR101032307B1 (ko) | 2008-10-02 | 2011-05-06 | 전북대학교병원 | 생체적합성 분자광학영상용 양자점 및 이의 제조방법 |
KR20220103718A (ko) * | 2019-10-18 | 2022-07-22 | 가부시키가이샤 바이오지프코드 | 줄기 세포 이동제를 사용한 당뇨병 치료 |
JPWO2022181797A1 (zh) * | 2021-02-26 | 2022-09-01 |
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WO2000062798A2 (en) * | 1999-04-15 | 2000-10-26 | St. Elizabeth's Medical Center, Inc. | Angiogenic growth factors for treatment of peripheral neuropathy |
CN1551778A (zh) * | 2001-09-05 | 2004-12-01 | ɽ����ʽ���� | 用于糖尿病神经病变的药物组合物 |
CN1739502A (zh) * | 2005-09-08 | 2006-03-01 | 南京医科大学 | 苄达赖氨酸在制备治疗糖尿病周围神经病变药物中的应用 |
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CA1339071C (en) * | 1988-08-24 | 1997-07-29 | Koichiro Tsuji | Thrombus control agent |
JP3954004B2 (ja) * | 1991-12-26 | 2007-08-08 | 中外製薬株式会社 | 脳機能障害による疾患の予防・治療薬 |
JPH0741429A (ja) * | 1993-07-30 | 1995-02-10 | Mitsubishi Chem Corp | 神経障害改善薬 |
JP2003113085A (ja) * | 1998-04-23 | 2003-04-18 | Takeda Chem Ind Ltd | 神経栄養因子様作用剤 |
TR200401573T4 (tr) * | 2000-02-29 | 2004-08-23 | Pfizer Products Inc. | Stabilize edilmiş granülosit koloni uyarıcı faktör |
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US7785601B2 (en) * | 2002-12-31 | 2010-08-31 | Sygnis Bioscience Gmbh & Co. Kg | Methods of treating neurological conditions with hematopoietic growth factors |
CA2522322A1 (en) * | 2003-04-15 | 2004-10-28 | Chugai Seiyaku Kabushiki Kaisha | Agent for treating diabetes mellitus |
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WO2000062798A2 (en) * | 1999-04-15 | 2000-10-26 | St. Elizabeth's Medical Center, Inc. | Angiogenic growth factors for treatment of peripheral neuropathy |
CN1551778A (zh) * | 2001-09-05 | 2004-12-01 | ɽ����ʽ���� | 用于糖尿病神经病变的药物组合物 |
CN1739502A (zh) * | 2005-09-08 | 2006-03-01 | 南京医科大学 | 苄达赖氨酸在制备治疗糖尿病周围神经病变药物中的应用 |
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Also Published As
Publication number | Publication date |
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BRPI0718099A2 (pt) | 2013-11-05 |
PT2077852E (pt) | 2014-03-04 |
ES2448837T3 (es) | 2014-03-17 |
EP2077852A4 (en) | 2012-01-18 |
US20100048869A1 (en) | 2010-02-25 |
AU2007314854B2 (en) | 2014-01-16 |
EP2077852B1 (en) | 2013-11-27 |
JP5416589B2 (ja) | 2014-02-12 |
HK1132461A1 (en) | 2010-02-26 |
EP2077852A1 (en) | 2009-07-15 |
WO2008054098A1 (en) | 2008-05-08 |
RU2009116833A (ru) | 2010-12-10 |
MX2009004646A (es) | 2009-05-22 |
NZ576498A (en) | 2012-03-30 |
CA2667178C (en) | 2015-12-29 |
CA2667178A1 (en) | 2008-05-08 |
KR100812274B1 (ko) | 2008-03-13 |
CN101528251A (zh) | 2009-09-09 |
UA93581C2 (ru) | 2011-02-25 |
JP2010508265A (ja) | 2010-03-18 |
RU2448726C2 (ru) | 2012-04-27 |
AU2007314854A1 (en) | 2008-05-08 |
US20110076247A1 (en) | 2011-03-31 |
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