CN101524120A - Vitamin premix for juvenile sea cucumbers and preparation method thereof - Google Patents
Vitamin premix for juvenile sea cucumbers and preparation method thereof Download PDFInfo
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- CN101524120A CN101524120A CN200910011192A CN200910011192A CN101524120A CN 101524120 A CN101524120 A CN 101524120A CN 200910011192 A CN200910011192 A CN 200910011192A CN 200910011192 A CN200910011192 A CN 200910011192A CN 101524120 A CN101524120 A CN 101524120A
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- 241000251511 Holothuroidea Species 0.000 title claims abstract description 39
- 230000000366 juvenile effect Effects 0.000 title claims abstract description 25
- 238000002360 preparation method Methods 0.000 title claims abstract description 15
- 235000019742 Vitamins premix Nutrition 0.000 title claims abstract description 14
- OVBPIULPVIDEAO-LBPRGKRZSA-N folic acid Chemical compound C=1N=C2NC(N)=NC(=O)C2=NC=1CNC1=CC=C(C(=O)N[C@@H](CCC(O)=O)C(O)=O)C=C1 OVBPIULPVIDEAO-LBPRGKRZSA-N 0.000 claims abstract description 30
- 229940088594 vitamin Drugs 0.000 claims abstract description 27
- 229930003231 vitamin Natural products 0.000 claims abstract description 27
- 235000013343 vitamin Nutrition 0.000 claims abstract description 27
- 239000011782 vitamin Substances 0.000 claims abstract description 27
- CIWBSHSKHKDKBQ-JLAZNSOCSA-N Ascorbic acid Chemical compound OC[C@H](O)[C@H]1OC(=O)C(O)=C1O CIWBSHSKHKDKBQ-JLAZNSOCSA-N 0.000 claims abstract description 26
- GHOKWGTUZJEAQD-ZETCQYMHSA-N (D)-(+)-Pantothenic acid Chemical compound OCC(C)(C)[C@@H](O)C(=O)NCCC(O)=O GHOKWGTUZJEAQD-ZETCQYMHSA-N 0.000 claims abstract description 24
- PVNIIMVLHYAWGP-UHFFFAOYSA-N Niacin Chemical compound OC(=O)C1=CC=CN=C1 PVNIIMVLHYAWGP-UHFFFAOYSA-N 0.000 claims abstract description 24
- YBJHBAHKTGYVGT-ZKWXMUAHSA-N (+)-Biotin Chemical compound N1C(=O)N[C@@H]2[C@H](CCCCC(=O)O)SC[C@@H]21 YBJHBAHKTGYVGT-ZKWXMUAHSA-N 0.000 claims abstract description 20
- OVBPIULPVIDEAO-UHFFFAOYSA-N N-Pteroyl-L-glutaminsaeure Natural products C=1N=C2NC(N)=NC(=O)C2=NC=1CNC1=CC=C(C(=O)NC(CCC(O)=O)C(O)=O)C=C1 OVBPIULPVIDEAO-UHFFFAOYSA-N 0.000 claims abstract description 15
- 235000020958 biotin Nutrition 0.000 claims abstract description 15
- 229960000304 folic acid Drugs 0.000 claims abstract description 15
- 235000019152 folic acid Nutrition 0.000 claims abstract description 15
- 239000011724 folic acid Substances 0.000 claims abstract description 15
- GVJHHUAWPYXKBD-UHFFFAOYSA-N (±)-α-Tocopherol Chemical compound OC1=C(C)C(C)=C2OC(CCCC(C)CCCC(C)CCCC(C)C)(C)CCC2=C1C GVJHHUAWPYXKBD-UHFFFAOYSA-N 0.000 claims abstract description 14
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 claims abstract description 14
- QYSXJUFSXHHAJI-XFEUOLMDSA-N Vitamin D3 Natural products C1(/[C@@H]2CC[C@@H]([C@]2(CCC1)C)[C@H](C)CCCC(C)C)=C/C=C1\C[C@@H](O)CCC1=C QYSXJUFSXHHAJI-XFEUOLMDSA-N 0.000 claims abstract description 14
- ZZZCUOFIHGPKAK-UHFFFAOYSA-N D-erythro-ascorbic acid Natural products OCC1OC(=O)C(O)=C1O ZZZCUOFIHGPKAK-UHFFFAOYSA-N 0.000 claims abstract description 13
- 229930003268 Vitamin C Natural products 0.000 claims abstract description 13
- 229930003316 Vitamin D Natural products 0.000 claims abstract description 13
- 235000019154 vitamin C Nutrition 0.000 claims abstract description 13
- 239000011718 vitamin C Substances 0.000 claims abstract description 13
- 235000019166 vitamin D Nutrition 0.000 claims abstract description 13
- 239000011710 vitamin D Substances 0.000 claims abstract description 13
- 150000003710 vitamin D derivatives Chemical class 0.000 claims abstract description 13
- 229940046008 vitamin d Drugs 0.000 claims abstract description 13
- GHOKWGTUZJEAQD-UHFFFAOYSA-N Chick antidermatitis factor Natural products OCC(C)(C)C(O)C(=O)NCCC(O)=O GHOKWGTUZJEAQD-UHFFFAOYSA-N 0.000 claims abstract description 12
- SQUHHTBVTRBESD-UHFFFAOYSA-N Hexa-Ac-myo-Inositol Natural products CC(=O)OC1C(OC(C)=O)C(OC(C)=O)C(OC(C)=O)C(OC(C)=O)C1OC(C)=O SQUHHTBVTRBESD-UHFFFAOYSA-N 0.000 claims abstract description 12
- FAPWYRCQGJNNSJ-UBKPKTQASA-L calcium D-pantothenic acid Chemical compound [Ca+2].OCC(C)(C)[C@@H](O)C(=O)NCCC([O-])=O.OCC(C)(C)[C@@H](O)C(=O)NCCC([O-])=O FAPWYRCQGJNNSJ-UBKPKTQASA-L 0.000 claims abstract description 12
- 229960002079 calcium pantothenate Drugs 0.000 claims abstract description 12
- 229960000367 inositol Drugs 0.000 claims abstract description 12
- CDAISMWEOUEBRE-GPIVLXJGSA-N inositol Chemical compound O[C@H]1[C@H](O)[C@@H](O)[C@H](O)[C@H](O)[C@@H]1O CDAISMWEOUEBRE-GPIVLXJGSA-N 0.000 claims abstract description 12
- 229960003512 nicotinic acid Drugs 0.000 claims abstract description 12
- 235000001968 nicotinic acid Nutrition 0.000 claims abstract description 12
- 239000011664 nicotinic acid Substances 0.000 claims abstract description 12
- 229940055726 pantothenic acid Drugs 0.000 claims abstract description 12
- 235000019161 pantothenic acid Nutrition 0.000 claims abstract description 12
- 239000011713 pantothenic acid Substances 0.000 claims abstract description 12
- CDAISMWEOUEBRE-UHFFFAOYSA-N scyllo-inosotol Natural products OC1C(O)C(O)C(O)C(O)C1O CDAISMWEOUEBRE-UHFFFAOYSA-N 0.000 claims abstract description 12
- FPIPGXGPPPQFEQ-UHFFFAOYSA-N 13-cis retinol Natural products OCC=C(C)C=CC=C(C)C=CC1=C(C)CCCC1(C)C FPIPGXGPPPQFEQ-UHFFFAOYSA-N 0.000 claims abstract description 10
- FPIPGXGPPPQFEQ-BOOMUCAASA-N Vitamin A Natural products OC/C=C(/C)\C=C\C=C(\C)/C=C/C1=C(C)CCCC1(C)C FPIPGXGPPPQFEQ-BOOMUCAASA-N 0.000 claims abstract description 10
- FPIPGXGPPPQFEQ-OVSJKPMPSA-N all-trans-retinol Chemical compound OC\C=C(/C)\C=C\C=C(/C)\C=C\C1=C(C)CCCC1(C)C FPIPGXGPPPQFEQ-OVSJKPMPSA-N 0.000 claims abstract description 10
- 229960002685 biotin Drugs 0.000 claims abstract description 10
- 239000011616 biotin Substances 0.000 claims abstract description 10
- 235000019155 vitamin A Nutrition 0.000 claims abstract description 10
- 239000011719 vitamin A Substances 0.000 claims abstract description 10
- 229940045997 vitamin a Drugs 0.000 claims abstract description 10
- 229930003427 Vitamin E Natural products 0.000 claims abstract description 7
- WIGCFUFOHFEKBI-UHFFFAOYSA-N gamma-tocopherol Natural products CC(C)CCCC(C)CCCC(C)CCCC1CCC2C(C)C(O)C(C)C(C)C2O1 WIGCFUFOHFEKBI-UHFFFAOYSA-N 0.000 claims abstract description 7
- 235000019165 vitamin E Nutrition 0.000 claims abstract description 7
- 229940046009 vitamin E Drugs 0.000 claims abstract description 7
- 239000011709 vitamin E Substances 0.000 claims abstract description 7
- LXNHXLLTXMVWPM-UHFFFAOYSA-N pyridoxine Chemical compound CC1=NC=C(CO)C(CO)=C1O LXNHXLLTXMVWPM-UHFFFAOYSA-N 0.000 claims abstract 4
- AUNGANRZJHBGPY-UHFFFAOYSA-N D-Lyxoflavin Natural products OCC(O)C(O)C(O)CN1C=2C=C(C)C(C)=CC=2N=C2C1=NC(=O)NC2=O AUNGANRZJHBGPY-UHFFFAOYSA-N 0.000 claims abstract 2
- AUNGANRZJHBGPY-SCRDCRAPSA-N Riboflavin Chemical compound OC[C@@H](O)[C@@H](O)[C@@H](O)CN1C=2C=C(C)C(C)=CC=2N=C2C1=NC(=O)NC2=O AUNGANRZJHBGPY-SCRDCRAPSA-N 0.000 claims abstract 2
- 229930003451 Vitamin B1 Natural products 0.000 claims abstract 2
- 229930003471 Vitamin B2 Natural products 0.000 claims abstract 2
- RADKZDMFGJYCBB-UHFFFAOYSA-N pyridoxal hydrochloride Natural products CC1=NC=C(CO)C(C=O)=C1O RADKZDMFGJYCBB-UHFFFAOYSA-N 0.000 claims abstract 2
- 229960002477 riboflavin Drugs 0.000 claims abstract 2
- 229960003495 thiamine Drugs 0.000 claims abstract 2
- DPJRMOMPQZCRJU-UHFFFAOYSA-M thiamine hydrochloride Chemical compound Cl.[Cl-].CC1=C(CCO)SC=[N+]1CC1=CN=C(C)N=C1N DPJRMOMPQZCRJU-UHFFFAOYSA-M 0.000 claims abstract 2
- 235000010374 vitamin B1 Nutrition 0.000 claims abstract 2
- 239000011691 vitamin B1 Substances 0.000 claims abstract 2
- 235000019164 vitamin B2 Nutrition 0.000 claims abstract 2
- 239000011716 vitamin B2 Substances 0.000 claims abstract 2
- 235000019158 vitamin B6 Nutrition 0.000 claims abstract 2
- 239000011726 vitamin B6 Substances 0.000 claims abstract 2
- 229940011671 vitamin b6 Drugs 0.000 claims abstract 2
- 150000001615 biotins Chemical class 0.000 claims description 5
- 229920002678 cellulose Polymers 0.000 claims description 4
- 238000005303 weighing Methods 0.000 claims description 4
- 239000012467 final product Substances 0.000 claims description 2
- 229940010007 cobalamins Drugs 0.000 claims 1
- 150000001867 cobalamins Chemical class 0.000 claims 1
- 230000012010 growth Effects 0.000 abstract description 15
- 230000000694 effects Effects 0.000 abstract description 7
- 239000000203 mixture Substances 0.000 abstract 3
- MJVAVZPDRWSRRC-UHFFFAOYSA-N Menadione Chemical compound C1=CC=C2C(=O)C(C)=CC(=O)C2=C1 MJVAVZPDRWSRRC-UHFFFAOYSA-N 0.000 abstract 2
- 229930003779 Vitamin B12 Natural products 0.000 abstract 2
- FDJOLVPMNUYSCM-WZHZPDAFSA-L cobalt(3+);[(2r,3s,4r,5s)-5-(5,6-dimethylbenzimidazol-1-yl)-4-hydroxy-2-(hydroxymethyl)oxolan-3-yl] [(2r)-1-[3-[(1r,2r,3r,4z,7s,9z,12s,13s,14z,17s,18s,19r)-2,13,18-tris(2-amino-2-oxoethyl)-7,12,17-tris(3-amino-3-oxopropyl)-3,5,8,8,13,15,18,19-octamethyl-2 Chemical compound [Co+3].N#[C-].N([C@@H]([C@]1(C)[N-]\C([C@H]([C@@]1(CC(N)=O)C)CCC(N)=O)=C(\C)/C1=N/C([C@H]([C@@]1(CC(N)=O)C)CCC(N)=O)=C\C1=N\C([C@H](C1(C)C)CCC(N)=O)=C/1C)[C@@H]2CC(N)=O)=C\1[C@]2(C)CCC(=O)NC[C@@H](C)OP([O-])(=O)O[C@H]1[C@@H](O)[C@@H](N2C3=CC(C)=C(C)C=C3N=C2)O[C@@H]1CO FDJOLVPMNUYSCM-WZHZPDAFSA-L 0.000 abstract 2
- 235000019163 vitamin B12 Nutrition 0.000 abstract 2
- 239000011715 vitamin B12 Substances 0.000 abstract 2
- 230000001900 immune effect Effects 0.000 abstract 1
- 235000012711 vitamin K3 Nutrition 0.000 abstract 1
- 239000011652 vitamin K3 Substances 0.000 abstract 1
- 239000002994 raw material Substances 0.000 description 21
- 150000003722 vitamin derivatives Chemical class 0.000 description 19
- 229930003448 Vitamin K Natural products 0.000 description 10
- SHUZOJHMOBOZST-UHFFFAOYSA-N phylloquinone Natural products CC(C)CCCCC(C)CCC(C)CCCC(=CCC1=C(C)C(=O)c2ccccc2C1=O)C SHUZOJHMOBOZST-UHFFFAOYSA-N 0.000 description 10
- 235000019168 vitamin K Nutrition 0.000 description 10
- 239000011712 vitamin K Substances 0.000 description 10
- 150000003721 vitamin K derivatives Chemical class 0.000 description 10
- 229940046010 vitamin k Drugs 0.000 description 10
- 150000001875 compounds Chemical class 0.000 description 8
- 239000000463 material Substances 0.000 description 6
- XWCYDHJOKKGVHC-UHFFFAOYSA-N Vitamin A2 Chemical compound OCC=C(C)C=CC=C(C)C=CC1=C(C)C=CCC1(C)C XWCYDHJOKKGVHC-UHFFFAOYSA-N 0.000 description 4
- 230000037396 body weight Effects 0.000 description 4
- 210000003419 coelomocyte Anatomy 0.000 description 4
- 230000036039 immunity Effects 0.000 description 4
- 235000016709 nutrition Nutrition 0.000 description 4
- 230000019254 respiratory burst Effects 0.000 description 4
- 235000019786 weight gain Nutrition 0.000 description 4
- 229910019142 PO4 Inorganic materials 0.000 description 3
- 238000002474 experimental method Methods 0.000 description 3
- NBIIXXVUZAFLBC-UHFFFAOYSA-K phosphate Chemical compound [O-]P([O-])([O-])=O NBIIXXVUZAFLBC-UHFFFAOYSA-K 0.000 description 3
- 239000010452 phosphate Substances 0.000 description 3
- 238000011160 research Methods 0.000 description 3
- PFTAWBLQPZVEMU-DZGCQCFKSA-N (+)-catechin Chemical compound C1([C@H]2OC3=CC(O)=CC(O)=C3C[C@@H]2O)=CC=C(O)C(O)=C1 PFTAWBLQPZVEMU-DZGCQCFKSA-N 0.000 description 2
- 241000208340 Araliaceae Species 0.000 description 2
- 235000005035 Panax pseudoginseng ssp. pseudoginseng Nutrition 0.000 description 2
- 235000003140 Panax quinquefolius Nutrition 0.000 description 2
- 230000000996 additive effect Effects 0.000 description 2
- DPRNENKPXAZQBI-UHFFFAOYSA-N alpha-Vitamin A Natural products OCC=C(C)C=CC=C(C)C=CC1C(C)=CCCC1(C)C DPRNENKPXAZQBI-UHFFFAOYSA-N 0.000 description 2
- 235000008434 ginseng Nutrition 0.000 description 2
- 208000026278 immune system disease Diseases 0.000 description 2
- 238000002372 labelling Methods 0.000 description 2
- 230000001228 trophic effect Effects 0.000 description 2
- 241000196324 Embryophyta Species 0.000 description 1
- 241001465754 Metazoa Species 0.000 description 1
- 239000000654 additive Substances 0.000 description 1
- 230000003698 anagen phase Effects 0.000 description 1
- 239000003674 animal food additive Substances 0.000 description 1
- 235000019728 animal nutrition Nutrition 0.000 description 1
- 238000009395 breeding Methods 0.000 description 1
- 230000001488 breeding effect Effects 0.000 description 1
- 238000011161 development Methods 0.000 description 1
- 230000018109 developmental process Effects 0.000 description 1
- 201000010099 disease Diseases 0.000 description 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 1
- 238000009826 distribution Methods 0.000 description 1
- 238000004519 manufacturing process Methods 0.000 description 1
- 238000000034 method Methods 0.000 description 1
- 235000015097 nutrients Nutrition 0.000 description 1
- 238000004806 packaging method and process Methods 0.000 description 1
- 239000000047 product Substances 0.000 description 1
- 238000012216 screening Methods 0.000 description 1
- 235000005282 vitamin D3 Nutrition 0.000 description 1
- 239000011647 vitamin D3 Substances 0.000 description 1
- QYSXJUFSXHHAJI-YRZJJWOYSA-N vitamin D3 Chemical compound C1(/[C@@H]2CC[C@@H]([C@]2(CCC1)C)[C@H](C)CCCC(C)C)=C\C=C1\C[C@@H](O)CCC1=C QYSXJUFSXHHAJI-YRZJJWOYSA-N 0.000 description 1
- RMDJVOZETBHEAR-LQYWTLTGSA-N vitamin D5 Chemical compound C1(/[C@@H]2CC[C@@H]([C@]2(CCC1)C)[C@H](C)CC[C@@H](CC)C(C)C)=C\C=C1\C[C@@H](O)CCC1=C RMDJVOZETBHEAR-LQYWTLTGSA-N 0.000 description 1
- 229940021056 vitamin d3 Drugs 0.000 description 1
Landscapes
- Fodder In General (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
The invention relates to a vitamin premix for juvenile sea cucumbers and a preparation method thereof. The invention is characterized in that the vitamin premix per ton comprises 500 thousand IU to 1000 thousand IU of vitamin A, 100 thousand IU to 500 thousand IU of vitamin D, 5g to 10g of vitamin E, 1g to 5g of vitamin K3, 1g to 5g of vitamin B1, 1g to 5g of vitamin B2, 1g to 5g of vitamin B6, 1g to 5g of vitamin B12, 0.5g to 15g of vitamin C, 5g to 10g of nicotinic acid, 100mg to 500mg of folic acid, 5g to 10g of pantothenic acid, 10g to 15g of inositol, 1g to 5g of calcium pantothenate, 10mg to 20mg of biotin and the balanced alpha-cellulose. The preparation method comprises the following steps: firstly weighting the vitamin D, the vitamin B12, the folic acid, the biotin and 100g of alpha-cellulose and mixing the same evenly; then, adding the other weighted vitamins and 500g of alpha-cellulose and mixing evenly the mixture; and finally, adding the rest alpha-cellulose to the mixture and mixing the new mixture to be fully even. The invention has the advantages that the growth performance and the immunologic competence of the juvenile sea cucumbers in a growth period are remarkably improved, the addition effect is stable, the cost is low and the application is convenient.
Description
Technical field
The invention belongs to field of feed additive technology, relate to a kind of additive that is added in the juvenile sea cucumbers artifical compound feed, be specifically related to juvenile sea cucumbers vitamin premix in growth period and preparation method thereof.
Background technology
Holothruian cultures have been the important economic industry in northern China coastal area.Along with the expansion of holothruian cultures scale and the rise of high-density breeding pattern, culture problems such as the sea cucumber growth performance is low, disease is frequently broken out and emerge in an endless stream, seriously restrict the sound development of this industry.How accelerating the speed of growth of sea cucumber and improving its immune disease-resistance ability becomes the sector problem that needs to be resolved hurrily at present.
The animal nutrition viewpoint thinks that the trophic level of feed directly determines growth performance and the immune indexes of animal.Outstanding holothurian feed must be able to satisfy sea cucumber at different growing stage to various nutritional labelings, the particularly specific demand of some crucial nutritional labeling (as vitamin), thus keep good growth performance of sea cucumber and immune disease-resistance ability.Yet though the sea cucumber compound feed of existence in the market is of a great variety, quality is very different, lacks unified trophic level again, is difficult to fully satisfy the demand of sea cucumber to various vitamins; And price is higher, how to occur with perfect compound feed, rather than occurs with the premix form of independent packaging, can't satisfy some plants with self-supplying of feed ability demand to premix when formula feed.
The present invention is directed to current holothruian cultures present situation, set about,,, determined a kind of vitamin premix for juvenile sea cucumbers and preparation method thereof through repeated screening in conjunction with the juvenile sea cucumbers nutritional need and the physiological characteristic in growth period from the fundamental biological knowledge research of sea cucumber.This premix compatibility is superior, and nutrient balance degree height can fully satisfy the juvenile sea cucumbers growth phase to the demand of various vitamins and improve the sea cucumber growth performance and immune vigor.Simultaneously, owing to select materials rationally, this premix is with low cost, and additive effect is stable, and is therefore easy to utilize.At present, at home and abroad be engaged in and do not see the product and research report similar in the related science research field of holothruian cultures as yet with the present invention.
Summary of the invention
The technical problem to be solved in the present invention is that mixed feed is difficult to fully satisfy juvenile sea cucumbers to the demand of various vitamins and the shortage of juvenile sea cucumbers vitamin premix in growth period.At above problem, the invention provides a kind of according to growth period children ginseng nutritional need and the compatibility that designs of physiological characteristic superior, fully satisfy the juvenile sea cucumbers various vitamin requirements and the lower-cost vitamin premix for juvenile sea cucumbers in growth period.
The present invention adopts following technical scheme to realize: juvenile sea cucumbers vitamin premix in growth period, be as the criterion to prepare 1 kilogram of premix, and its component and consumption thereof are:
Vitamin A 500,000～1,000,000 IU (international unit);
VD1 00,000～500,000 IU;
Vitamin E 5～10 grams;
Vitamin K
31～5 gram;
Cobastab
11～5 gram;
Cobastab
21～5 gram;
Cobastab
61～5 gram;
Cobastab
125～10 milligrams;
Vitamin C 0.5～15 gram;
Nicotinic acid 5～10 grams;
100～500 milligrams in folic acid;
Pantothenic acid 5～10 grams;
Inositol 10～15 grams;
Calcium pantothenate 1～5 gram;
10～20 milligrams of biotins;
All the other are alpha-cellulose.
Above-mentioned various vitamins are 100% pure material, and used each material has certain purity in actual fabrication process, can easily converse the consumption of actual material by the use amount of pure material.Premix of the present invention is as the part of juvenile sea cucumbers artifical compound feed, can add in the feed by 1% the adding proportion that accounts for the feed total amount.Premix enters basestocks by enlarging premix step by step.
Another object of the present invention provides the preparation method of this premix.
The technical problem that this preparation method solves is how to guarantee all vitamins component, and especially the low content vitamin component distributes in this premix uniformly.The preparation method of premix of the present invention comprises first weighing vitamin D, Cobastab
12, folic acid, biotin and 100 gram alpha-celluloses place agitator; Start mixer, mix; Other vitamins of weighing again, and place agitator with 500 gram alpha-celluloses; To be mixedly evenly will remain alpha-cellulose after not having dirt to fly and pour in the agitator, and mix and get final product.
Effect of the present invention and benefit are fully to satisfy the juvenile sea cucumbers vitamin demand in growth period, and significantly improve the growth performance and the immune vigor of children's ginseng.Preparation method provided by the invention can guarantee the even distribution of each vitamin component in this premix simultaneously, and then has guaranteed the quality of premix and stable effect.Use the sea cucumber compound feed that adds this premix to throw something and feed juvenile sea cucumbers after 60 days, compare with the control group that does not add this premix, the body weight gain of sea cucumber is higher than control group 71～84%, immunity index antalzyme activity improves 52～146%, coelomocyte is engulfed vigor and is improved 11～65%, breathes the oxidative burst vigor and improves 24～70%.In addition, the present invention selects materials rationally, and is with low cost and the preparation method is easy, is easy to promotion and application.
The specific embodiment
Be described in detail specific embodiments of the invention below in conjunction with technical scheme.
Embodiment 1
Vitamin premix for juvenile sea cucumbers is as the criterion to prepare 1 kilogram of premix, and its component and consumption thereof are:
Vitamin A 500,000 IU;
VD1 00,000 IU;
Vitamin E 5 grams;
Vitamin K
31 gram;
Cobastab
11 gram;
Cobastab
21 gram;
Cobastab
61 gram;
Cobastab
125 milligrams;
Vitamin C 0.5 gram;
Nicotinic acid 5 grams;
100 milligrams in folic acid;
Pantothenic acid 5 grams;
Inositol 10 grams;
Calcium pantothenate 1 gram;
10 milligrams of biotins;
All the other are alpha-cellulose.
Vitamin A derives from the actual vitamin A raw material that purity is 500,000 IU/g; Vitamin D derives from the actual vitamin D raw material that purity is 500,000 IU/g; Source of vitamin E is 50% actual Vitwas E raw material in purity; It is 25% actual vitamin C condensed phosphate raw material that vitamin C derives from purity; The purity of the actual raw material of other each vitamin is:
Vitamin K
394%;
Cobastab
198%;
Cobastab
298%;
Cobastab
698%;
Cobastab
121%;
Nicotinic acid 98%;
Folic acid 98%;
Pantothenic acid 98%;
Inositol 98%;
Calcium pantothenate 99%;
Biotin 2%;
By the purity of above-mentioned each vitamin raw materials, can calculate the consumption of actual vitamin raw materials:
The retinol1 gram;
Vitamin D 0.2 gram;
Vitamin e1 0 gram;
Vitamin K
31.1 gram;
Cobastab
11 gram;
Cobastab
21 gram;
Cobastab
61 gram;
Cobastab
120.5 gram;
The Catergen gram;
Nicotinic acid 5 grams;
Folic acid 0.1 gram;
Pantothenic acid 5 grams;
Inositol 10 grams;
Calcium pantothenate 1 gram;
Biotin 0.5 gram;
Alpha-cellulose 960.6 grams.
By preparation method provided by the invention above each component is prepared into premix, and sneak in the sea cucumber compound feed with 1% adding proportion in the mode that enlarges step by step, the experiment of feeding through 60 days, compare with the control group that does not add premix, the juvenile sea cucumbers body weight gain is higher than control group 71%, immunity index antalzyme activity improves 52%, and coelomocyte is engulfed vigor and improved 11%, breathes the oxidative burst vigor and improves 24%.
Embodiment 2
Vitamin premix for juvenile sea cucumbers is as the criterion to prepare 1 kilogram of premix, and its component and consumption thereof are:
Retinol1 000,000 IU;
Cholecalciferol 00,000 IU;
Vitamin e1 0 gram;
Vitamin K
31 gram;
Cobastab
12 grams;
Cobastab
22 grams;
Cobastab
61.5 gram;
Cobastab
125 milligrams;
Vitamin C 5 grams;
Nicotinic acid 7.5 grams;
400 milligrams in folic acid;
Pantothenic acid 5 grams;
Inositol 15 grams;
Calcium pantothenate 1 gram;
10 milligrams of biotins;
All the other are alpha-cellulose.
Vitamin A derives from the actual vitamin A raw material that purity is 500,000 IU/g; Vitamin D derives from the actual vitamin D raw material that purity is 500,000 IU/g; Source of vitamin E is 50% actual Vitwas E raw material in purity; It is 25% actual vitamin C condensed phosphate raw material that vitamin C derives from purity; The purity of the actual raw material of other each vitamin is:
Vitamin K
394%;
Cobastab
198%;
Cobastab
298%;
Cobastab
698%;
Cobastab
121%;
Nicotinic acid 98%;
Folic acid 98%;
Pantothenic acid 98%;
Inositol 98%;
Calcium pantothenate 99%;
Biotin 2%.
By the purity of above-mentioned each vitamin raw materials, can calculate the consumption of actual vitamin raw materials:
The dehydroretinol gram;
Vitamin D 0.6 gram;
Vitamin E2 0 gram;
Vitamin K
31.1 gram;
Cobastab
12.04 gram;
Cobastab
22.04 gram;
Cobastab
61.53 gram;
Cobastab
120.5 gram;
Catergen 0 gram;
Nicotinic acid 8.16 grams;
Folic acid 0.41 gram;
Pantothenic acid 5.10 grams;
Inositol 15.31 grams;
Calcium pantothenate 1 gram;
Biotin 0.5 gram;
Alpha-cellulose 919.71 grams.
By preparation method provided by the invention above each component is prepared into premix, and sneak in the sea cucumber compound feed with 1% adding proportion in the mode that enlarges step by step, the experiment of feeding through 60 days, compare with the control group that does not add premix, the juvenile sea cucumbers body weight gain is higher than control group 84%, immunity index antalzyme activity improves 146%, and coelomocyte is engulfed vigor and improved 65%, breathes the oxidative burst vigor and improves 70%.
Embodiment 3
Vitamin premix for juvenile sea cucumbers is as the criterion to prepare 1 kilogram of premix, and its component and consumption thereof are:
Retinol1 000,000 IU;
Vitamin D5 00,000 IU;
Vitamin e1 0 gram;
Vitamin K
35 grams;
Cobastab
15 grams;
Cobastab
25 grams;
Cobastab
65 grams;
Cobastab
1210 milligrams;
Vitamin C 15 grams;
Nicotinic acid 10 grams;
500 milligrams in folic acid;
Pantothenic acid 10 grams;
Inositol 15 grams;
Calcium pantothenate 5 grams;
20 milligrams of biotins;
All the other are alpha-cellulose.
Vitamin A derives from the actual vitamin A raw material that purity is 500,000 IU/g; Vitamin D derives from the actual vitamin D raw material that purity is 500,000 IU/g; Source of vitamin E is 50% actual Vitwas E raw material in purity; It is 25% actual vitamin C condensed phosphate raw material that vitamin C derives from purity; The purity of the actual raw material of other each vitamin is:
Vitamin K
394%;
Cobastab
198%;
Cobastab
298%;
Cobastab
698%;
Cobastab
121%;
Nicotinic acid 98%;
Folic acid 98%;
Pantothenic acid 98%;
Inositol 98%;
Calcium pantothenate 99%;
Biotin 2%.
By the purity of above-mentioned each vitamin raw materials, can calculate the consumption of actual vitamin raw materials:
The dehydroretinol gram;
The VD1 gram;
Vitamin E2 0 gram;
Vitamin K
35.32 gram;
Cobastab
15.10 gram;
Cobastab
25.10 gram;
Cobastab
65.10 gram;
Cobastab
121 gram;
Vitamin C 60 grams;
Nicotinic acid 10.20 grams;
Folic acid 0.51 gram;
Pantothenic acid 10.20 grams;
Inositol 15.31 grams;
Calcium pantothenate 5.10 grams;
Biotin 1 gram;
Alpha-cellulose 853.07 grams.
By preparation method provided by the invention above each component is prepared into premix, and sneak in the sea cucumber compound feed with 1% adding proportion in the mode that enlarges step by step, the experiment of feeding through 60 days, compare with the control group that does not add premix, the juvenile sea cucumbers body weight gain is higher than control group 80%, immunity index antalzyme activity improves 84%, and coelomocyte is engulfed vigor and improved 43%, breathes the oxidative burst vigor and improves 58%.
Claims (2)
1. vitamin premix for juvenile sea cucumbers, it is characterized by: be as the criterion to prepare 1 kilogram of premix, its component and consumption thereof are:
Vitamin A 500,000～1,000,000 IU (international unit);
Vitamin D 100,000～500,000 IU;
Vitamin E 5～10 grams;
Prokeyvit 1～5 gram;
Vitamin B1 1～5 gram;
Vitamin B2 1～5 gram;
Vitamin B6 1～5 gram;
5～10 milligrams of cobalamins;
Vitamin C 0.5～15 gram;
Nicotinic acid 5～10 grams;
100～500 milligrams in folic acid;
Pantothenic acid 5～10 grams;
Inositol 10～15 grams;
Calcium pantothenate 1～5 gram;
10～20 milligrams of biotins;
All the other are alpha-cellulose.
2, the described vitamin premix for juvenile sea cucumbers preparation method of claim 1, its feature comprises first weighing vitamin D, Cobastab
12, folic acid, biotin and 100 gram alpha-celluloses place agitator; Start mixer, mix; Other vitamins of weighing again, and add in the agitator together with 500 gram alpha-celluloses; To be mixedly evenly will remain alpha-cellulose after not having dirt to fly and add in the agitator, and mix and get final product.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN200910011192A CN101524120A (en) | 2009-04-16 | 2009-04-16 | Vitamin premix for juvenile sea cucumbers and preparation method thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN200910011192A CN101524120A (en) | 2009-04-16 | 2009-04-16 | Vitamin premix for juvenile sea cucumbers and preparation method thereof |
Publications (1)
| Publication Number | Publication Date |
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ID=41092327
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| Application Number | Title | Priority Date | Filing Date |
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Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102648735A (en) * | 2012-04-28 | 2012-08-29 | 曹金党 | Composite premix for sea cucumbers |
| CN102726611A (en) * | 2012-06-21 | 2012-10-17 | 格特生物制药（天津）有限公司 | Forage for supplementing vitamins to sea cucumbers, its preparation method and its use method |
| CN102835588A (en) * | 2011-06-20 | 2012-12-26 | 威海金牌饲料有限公司 | Pellet compound feed used for fully grown sea cucumber |
| CN102960556A (en) * | 2012-11-05 | 2013-03-13 | 山东省海水养殖研究所 | Young oplopanax elatus feed mainly prepared from enteromorpha and preparation method and feeding method thereof |
-
2009
- 2009-04-16 CN CN200910011192A patent/CN101524120A/en active Pending
Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102835588A (en) * | 2011-06-20 | 2012-12-26 | 威海金牌饲料有限公司 | Pellet compound feed used for fully grown sea cucumber |
| CN102835588B (en) * | 2011-06-20 | 2014-06-11 | 威海金牌生物科技有限公司 | Pellet compound feed used for fully grown sea cucumber |
| CN102648735A (en) * | 2012-04-28 | 2012-08-29 | 曹金党 | Composite premix for sea cucumbers |
| CN102726611A (en) * | 2012-06-21 | 2012-10-17 | 格特生物制药（天津）有限公司 | Forage for supplementing vitamins to sea cucumbers, its preparation method and its use method |
| CN102960556A (en) * | 2012-11-05 | 2013-03-13 | 山东省海水养殖研究所 | Young oplopanax elatus feed mainly prepared from enteromorpha and preparation method and feeding method thereof |
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Open date: 20090909 |