CN101506128B - 高速甲基化法、pet示踪剂制备用试剂盒以及pet用示踪剂的制造方法 - Google Patents
高速甲基化法、pet示踪剂制备用试剂盒以及pet用示踪剂的制造方法 Download PDFInfo
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- CN101506128B CN101506128B CN2007800315616A CN200780031561A CN101506128B CN 101506128 B CN101506128 B CN 101506128B CN 2007800315616 A CN2007800315616 A CN 2007800315616A CN 200780031561 A CN200780031561 A CN 200780031561A CN 101506128 B CN101506128 B CN 101506128B
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- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B59/00—Introduction of isotopes of elements into organic compounds ; Labelled organic compounds per se
- C07B59/001—Acyclic or carbocyclic compounds
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- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B37/00—Reactions without formation or introduction of functional groups containing hetero atoms, involving either the formation of a carbon-to-carbon bond between two carbon atoms not directly linked already or the disconnection of two directly linked carbon atoms
- C07B37/04—Substitution
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- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B59/00—Introduction of isotopes of elements into organic compounds ; Labelled organic compounds per se
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- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C1/00—Preparation of hydrocarbons from one or more compounds, none of them being a hydrocarbon
- C07C1/32—Preparation of hydrocarbons from one or more compounds, none of them being a hydrocarbon starting from compounds containing hetero-atoms other than or in addition to oxygen or halogen
- C07C1/321—Preparation of hydrocarbons from one or more compounds, none of them being a hydrocarbon starting from compounds containing hetero-atoms other than or in addition to oxygen or halogen the hetero-atom being a non-metal atom
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C17/00—Preparation of halogenated hydrocarbons
- C07C17/26—Preparation of halogenated hydrocarbons by reactions involving an increase in the number of carbon atoms in the skeleton
- C07C17/263—Preparation of halogenated hydrocarbons by reactions involving an increase in the number of carbon atoms in the skeleton by condensation reactions
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- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C205/00—Compounds containing nitro groups bound to a carbon skeleton
- C07C205/06—Compounds containing nitro groups bound to a carbon skeleton having nitro groups bound to carbon atoms of six-membered aromatic rings
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- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C29/00—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring
- C07C29/32—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring increasing the number of carbon atoms by reactions without formation of -OH groups
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- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C41/00—Preparation of ethers; Preparation of compounds having groups, groups or groups
- C07C41/01—Preparation of ethers
- C07C41/18—Preparation of ethers by reactions not forming ether-oxygen bonds
- C07C41/30—Preparation of ethers by reactions not forming ether-oxygen bonds by increasing the number of carbon atoms, e.g. by oligomerisation
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C67/00—Preparation of carboxylic acid esters
- C07C67/30—Preparation of carboxylic acid esters by modifying the acid moiety of the ester, such modification not being an introduction of an ester group
- C07C67/333—Preparation of carboxylic acid esters by modifying the acid moiety of the ester, such modification not being an introduction of an ester group by isomerisation; by change of size of the carbon skeleton
- C07C67/343—Preparation of carboxylic acid esters by modifying the acid moiety of the ester, such modification not being an introduction of an ester group by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B2200/00—Indexing scheme relating to specific properties of organic compounds
- C07B2200/05—Isotopically modified compounds, e.g. labelled
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2531/00—Catalysts comprising hydrides, coordination complexes or organic compounds
- C07C2531/16—Catalysts comprising hydrides, coordination complexes or organic compounds containing coordination complexes
- C07C2531/24—Phosphines
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
- C07C2601/16—Systems containing only non-condensed rings with a six-membered ring the ring being unsaturated
Abstract
Description
Claims (42)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
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JP2006229169 | 2006-08-25 | ||
JP229169/2006 | 2006-08-25 | ||
PCT/JP2007/066411 WO2008023780A1 (fr) | 2006-08-25 | 2007-08-24 | Procédé de méthylation rapide, coffret pour préparer un traceur pet et procédé de fabrication d'un traceur pet |
Publications (2)
Publication Number | Publication Date |
---|---|
CN101506128A CN101506128A (zh) | 2009-08-12 |
CN101506128B true CN101506128B (zh) | 2013-07-03 |
Family
ID=39106862
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CN2007800315616A Active CN101506128B (zh) | 2006-08-25 | 2007-08-24 | 高速甲基化法、pet示踪剂制备用试剂盒以及pet用示踪剂的制造方法 |
Country Status (5)
Country | Link |
---|---|
US (1) | US8288604B2 (zh) |
EP (1) | EP2070897B1 (zh) |
JP (1) | JP5279077B2 (zh) |
CN (1) | CN101506128B (zh) |
WO (1) | WO2008023780A1 (zh) |
Families Citing this family (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2010037238A (ja) * | 2008-08-01 | 2010-02-18 | Arata Yamazaki | ビアリール化合物の製造方法 |
US9012632B2 (en) | 2008-12-26 | 2015-04-21 | Riken | Method for rapidly methylating heteroaromatic arene and method for producing tracer for use in PET |
GB0905515D0 (en) * | 2009-03-31 | 2009-05-13 | Ge Healthcare Ltd | Radiolabelling methods |
JP5777163B2 (ja) * | 2009-07-03 | 2015-09-09 | 国立研究開発法人理化学研究所 | Pet用標識化合物 |
JP5618042B2 (ja) * | 2009-09-21 | 2014-11-05 | 国立大学法人岐阜大学 | アイソトープ標識化合物及びアイソトープ標識化合物前駆体 |
WO2011068181A1 (ja) * | 2009-12-04 | 2011-06-09 | 独立行政法人理化学研究所 | 高速フルオロメチル化法及びそれを利用したpetトレーサーの製造方法 |
CN102452873B (zh) * | 2010-10-27 | 2014-06-18 | 北京大基康明医疗设备有限公司 | 含碳或氧同位素化合物、制备方法、应用以及组合物 |
JP6037330B2 (ja) * | 2012-03-03 | 2016-12-07 | 国立研究開発法人理化学研究所 | 11c−標識チアミン及びその誘導体、11c−標識フルスルチアミン、チアミン前駆体、並びにpet用プローブ及びそれらを用いたイメージング方法 |
JP2015178456A (ja) * | 2012-07-18 | 2015-10-08 | 国立研究開発法人理化学研究所 | 高速メチル化法 |
WO2014030709A1 (ja) * | 2012-08-24 | 2014-02-27 | 浜松ホトニクス株式会社 | ミトコンドリアComplex-1の検出に適した化合物 |
WO2014065874A1 (en) * | 2012-10-26 | 2014-05-01 | University Of Southern California | 18f labeled bodipy dye and its derivatives for pet imaging of heart perfusion and others |
WO2015137175A1 (ja) * | 2014-03-10 | 2015-09-17 | 国立研究開発法人理化学研究所 | アリールボロン酸エステル化合物の製造方法 |
JP2019014652A (ja) * | 2015-11-26 | 2019-01-31 | 国立研究開発法人理化学研究所 | 芳香族化合物のメチル化方法 |
Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20010020104A1 (en) * | 2000-02-22 | 2001-09-06 | Clariant Gmbh | Process for preparing substituted benzyl compounds and toluene derivatives |
US20040131544A1 (en) * | 1999-10-22 | 2004-07-08 | Maclean Derek | In vivo imaging |
CN1745049A (zh) * | 2002-12-09 | 2006-03-08 | 麻省理工学院 | 金属配体以及以此为基础的改良的金属催化方法 |
Family Cites Families (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE4420670A1 (de) | 1993-06-28 | 1995-01-05 | Gen Electric | Verfahren zum Herstellen von (11C)Methyliodid |
JP4159653B2 (ja) | 1998-05-22 | 2008-10-01 | 池田食研株式会社 | [11c]−l−メチオニンの合成方法 |
JP2002308615A (ja) | 2001-04-04 | 2002-10-23 | Sumitomo Heavy Ind Ltd | 11c−ホスゲンの合成方法及び装置 |
JP2002308613A (ja) | 2001-04-10 | 2002-10-23 | 健郎 ▲とう▼ | 活性炭の製造方法 |
GB0115929D0 (en) | 2001-06-29 | 2001-08-22 | Nycomed Amersham Plc | Solid-phase electrophilic fluorination |
DK2583958T3 (en) | 2002-12-09 | 2016-11-28 | Massachusetts Inst Of Tech (Mit) | LIGANDS OF METALS AND IMPROVED METAL catalyzed processes based thereon |
JP4238352B2 (ja) | 2003-08-07 | 2009-03-18 | 独立行政法人放射線医学総合研究所 | [11c]ハロゲン化メチルの合成方法 |
WO2007046258A1 (ja) | 2005-10-21 | 2007-04-26 | Gifu University | アルケン類の高速メチル化法及びそれを利用したpetトレーサー調製用キット |
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2007
- 2007-08-24 EP EP07806029.0A patent/EP2070897B1/en active Active
- 2007-08-24 JP JP2008530959A patent/JP5279077B2/ja active Active
- 2007-08-24 US US12/438,711 patent/US8288604B2/en active Active
- 2007-08-24 WO PCT/JP2007/066411 patent/WO2008023780A1/ja active Search and Examination
- 2007-08-24 CN CN2007800315616A patent/CN101506128B/zh active Active
Patent Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20040131544A1 (en) * | 1999-10-22 | 2004-07-08 | Maclean Derek | In vivo imaging |
US20010020104A1 (en) * | 2000-02-22 | 2001-09-06 | Clariant Gmbh | Process for preparing substituted benzyl compounds and toluene derivatives |
CN1745049A (zh) * | 2002-12-09 | 2006-03-08 | 麻省理工学院 | 金属配体以及以此为基础的改良的金属催化方法 |
Also Published As
Publication number | Publication date |
---|---|
US20100249477A1 (en) | 2010-09-30 |
US8288604B2 (en) | 2012-10-16 |
JP5279077B2 (ja) | 2013-09-04 |
EP2070897A1 (en) | 2009-06-17 |
WO2008023780A1 (fr) | 2008-02-28 |
EP2070897A4 (en) | 2015-12-30 |
EP2070897B1 (en) | 2018-04-18 |
CN101506128A (zh) | 2009-08-12 |
JPWO2008023780A1 (ja) | 2010-01-14 |
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Free format text: FORMER OWNER: PHYSICAL CHEMISTRY INST HAMAMATSU PHOTONICS K. K. Effective date: 20130821 Owner name: HAMAMATSU PHOTONICS K. K. Free format text: FORMER OWNER: UNIV GIFU Effective date: 20130821 |
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Effective date of registration: 20130821 Address after: Shizuoka Patentee after: Hamamatsu Photonics K. K. Address before: Gifu County, Japan Patentee before: Univ Gifu Patentee before: Independent Administrative Institution Physical Chemistry Institute Patentee before: Hamamatsu Photonics K. K. |