CN101485868A

CN101485868A - Pharmaceutical composition for dispersing swelling and relieving pain and preparation method thereof

Info

Publication number: CN101485868A
Application number: CN 200810056303
Authority: CN
Inventors: 王丽娟
Original assignee: BEIJING TIANKE RENXIANG MEDICAL SCI-TECH Co Ltd
Current assignee: BEIJING TIANKE RENXIANG MEDICAL SCI-TECH Co Ltd
Priority date: 2008-01-16
Filing date: 2008-01-16
Publication date: 2009-07-22

Abstract

The invention discloses a medicine composition for reducing swelling and stopping pain and a preparation method thereof. The preparation method comprises: taking Chuanxiong rhizome, liquorice, safflower, Corydalis yanhusuo, rhubarb, Chinese angelica, frankincense, wild chrysanthemum flower, dandelion, leatherleaf mahonia, ginger, rosin, Polygonum multiform, Angelica dahurica, gelatin and other raw materials according to proportion of a formula, extracting effective ingredients, and adding the gelatin to prepare ointment, pellicle and powder for external application. Various medicines of the medicine composition are compatible, and the medicine composition has the efficacies of clearing and activating the channels and collaterals, reducing swelling and stopping pain, activating blood circulation to dissolve stasis, expelling wind and clearing away cold, and clearing out pus and drawing out pus by applying a plaster to the affected area. The medicine composition has the advantages that the medicine composition can quickly reduce swelling and stop pain, has long treatment effect time, good analgesic effect and no toxic and side effect, is safe and convenient to use, is a preferred externally applied agent for treating diseases such as injuries from falls, cervical spondylosis, carbuncle and furuncle, and simultaneously is a novel externally applied traditional Chinese medicine preparation with popularization value.

Description

A kind of drug regimen that is used for reducing swelling and alleviating pain and preparation method thereof

Technical field

The invention belongs to the Chinese medicine preparation technical field, be specifically related to a kind of drug regimen that is used for reducing swelling and alleviating pain and preparation method thereof, is drug regimen and the preparation method that is used for diseases such as osteopatia sprain, cervical spondylosis, furuncle, furuncle be swollen specifically.

Technical background

Spraining swells and ache is common multiple illness, and etiology and pathogenesis is the external force effect, and damage muscle flesh skeleton causes meridians to hinder coagulation of QI-blood.Human body is pounded, is collided or run and the external force effect such as pounce on, bear a heavy burden, reverse because of hitting, pressing, and causes a large amount of capillary ruptures of organization internal of injury, and blood oozes out rapidly, has destroyed normal microcirculatory balance, forms local congestion.Symptom is that local swelling, pain, ecchymosis, limb activity are limited etc.Sprain back injury congestion swelling, blockage of main and collateral channels, QI and blood retardance.

Cervical spondylosis is because people often bow and bend over the desk mostly, makes the normal physiology of cervical vertebra bend degree and becomes straight, causes a lot of other variations of cervical vertebra (as loosening, hypertrophy, muscular tone etc.), thereby stimulates peripheral nerve or blood vessel, causes the cervical vertebra slight illness.

It is the acute festering type infection that malignant bacteria is invaded hair follicle or caused single hair follicle of sweat gland and affiliated sebaceous gland thereof that furuncle, furuncle swell.Be called " summer-heat furuncle " again.Multidigit is in neck portion, head and portion, back, buttocks, oxter, perineal position and shank.Topical manifestations is red, swollen, hot, bitterly in the clinical manifestation, is lesser tubercle, and can increases gradually, tapered protuberance.White little purulent core appears in central then deliquescing.When the whole body resistance reduced, fear of cold, heating can appear.

More than these illness be because muscle blood is not lived blood capillary and microcirculation smooth due to, most of people are general, and normal employing is treated such as methods such as physiotherapy, operation, endo-medicines, so complicated, the curative effect of treatment not rapidly, side effect greatly and cost an arm and a leg.Preferably adopt external medication targetedly, external application tradition surgery of Chinese medicine plaster, remarkable by plaster external application effect.The Chinese medicine preparation of external application just arises at the historic moment like this, but some liniments that occur on the market, specific aim is not strong, and the efficacy of a drug can not well be concentrated, and obviously just can not effectively be penetrated into deep tissues, and the effect of reducing swelling and alleviating pain has just been lost.The present invention by skin conductance to meridians, muscles and bones, excite the regulatory function of human body, can eliminate rapidly and swell and ache, the effect that makes dredge the meridian passage, reducing swelling and alleviating pain, promoting blood circulation to remove blood stasis, expelling wind and cold, evacuation of pus draw out pus by applying a plaster to the affected part is greatly improved, and promotes functional rehabilitation and reaches the healing purpose fast.

Therefore, patient colony is huge, and the medicine of treatment reducing swelling and alleviating pain has the very big market space, so medicine of the present invention will bring huge social benefit and economic benefit.

Summary of the invention

Be to provide a kind of drug regimen that is used to cure illness such as osteopatia sprain, cervical spondylosis, furuncle, furuncle be swollen of preparation and preparation method thereof, to overcome the deficiency of existing medicine order of the present invention.

Be achieved through the following technical solutions order of the present invention:

1, the present invention is the preparation of being made by the following weight proportion raw material:

30-80 parts on 15-40 parts of Flos Carthamis of 15-40 parts of Radix Glycyrrhizaes of Rhizoma Chuanxiong

20-45 parts of 8-30 parts of Radix Angelicae Sinensis of 10-30 parts of Radix Et Rhizoma Rhei of Rhizoma Corydalis

20-50 parts of 20-45 parts of Herba Taraxacis of 8-25 parts of Flos Chrysanthemi Indicis of Olibanum

20-40 parts of 15-35 parts of Colophonium of 20-45 portions of Rhizoma Zingiberis Recenss of Caulis Mahoniae

20-50 parts in 15-50 parts of gelatin of 15-35 parts of Radixs Angelicae Dahuricae of Herba Violae

2, best each the raw material weight proportioning of prescription of the present invention is:

55 parts on 22 parts of Flos Carthamis of 25 portions of Radix Glycyrrhizaes of Rhizoma Chuanxiong

30 parts of 15 parts of Radix Angelicae Sinensis of 15 parts of Radix Et Rhizoma Rhei of Rhizoma Corydalis

33 parts of 11 parts of Herba Taraxacis of 11 parts of Flos Chrysanthemi Indicis of Olibanum

15 parts of 30 parts of Colophonium of 30 portions of Rhizoma Zingiberis Recenss of Caulis Mahoniae

33 parts in 25 parts of gelatin of 30 parts of Radixs Angelicae Dahuricae of Herba Violae

3, preparation technology

(1) get Rhizoma Zingiberis Recens, the alcohol dipping with 60～70% 24～48 hours filters, and collects filtrate, and is standby;

(2) get Rhizoma Chuanxiong, Flos Carthami, Radix Angelicae Sinensis, Olibanum, Colophonium powder and be broken into coarse powder, according to the percolation under fluid extract and the extractum item (appendix IO of Chinese Pharmacopoeia version in 2005), ethanol with 65～75% is made solvent, flood and carry out percolation (18～25 ℃) after 48-96 hour, with the speed of per minute 1～3ml percolation slowly, collect the about 800～1500ml of percolate, left standstill 24 hours, filter filtrate for later use;

(3) extracting liquorice, Rhizoma Corydalis, Radix Et Rhizoma Rhei, Flos Chrysanthemi Indici, Herba Taraxaci, Caulis Mahoniae, Herba Violae, each medicine of the Radix Angelicae Dahuricae decoct with water 2～4 times, each 1～3 hour, filter merging filtrate; Add ethanol in filtrate, make that concentration of alcohol reaches 50～65% (V/V) in the filtrate, cold preservation 12 hours filters, and decompression filtrate recycling ethanol is to concentrated solution;

(4) with above-mentioned three kinds of filtrates, behind mixing, under 60～80 ℃ temperature, be concentrated into relative density and be 1.33～1.35 thick paste, add gelatin, make the unguentum, membrane, the powder that are used for external application.

The present invention does not contain the hypertoxicity composition, no incompatibility, Rhizoma Chuanxiong, the Radix Angelicae Dahuricae have the effect of reducing swelling and alleviating pain in the side, Radix Angelicae Sinensis, Flos Carthami have the effect of blood circulation promoting and blood stasis dispelling, but the Rhizoma Zingiberis Recens warming middle-JIAO by cold, Colophonium dispeiling pathogenic wind and removing dampness, evacuation of pus are drawn out pus by applying a plaster to the affected part, granulation promoting pain relieving, the furuncle of living, furuncle are swollen.Adopt said medicine combination and preparation method thereof, all composition compatibilities are coordinated mutually, have the effect that dredge the meridian passage, reducing swelling and alleviating pain, promoting blood circulation to remove blood stasis, expelling wind and cold, evacuation of pus are drawn out pus by applying a plaster to the affected part.

Specific embodiment:

Adopt following prescription:

Its preparation technology is:

(1) get Rhizoma Zingiberis Recens, the alcohol dipping with 65% 24 hours filters, and collects filtrate, and is standby;

(2) get Rhizoma Chuanxiong, Flos Carthami, Radix Angelicae Sinensis, Olibanum, Colophonium powder and be broken into coarse powder, according to the percolation under fluid extract and the extractum item (appendix IO of Chinese Pharmacopoeia version in 2005), ethanol with 70% is made solvent, flood and carry out percolation (22 ℃) after 72 hours, with the speed of per minute 2ml percolation slowly, collect the about 1000ml of percolate, left standstill 24 hours, filter filtrate for later use;

(3) extracting liquorice, Rhizoma Corydalis, Radix Et Rhizoma Rhei, Flos Chrysanthemi Indici, Herba Taraxaci, Caulis Mahoniae, Herba Violae, each medicine of the Radix Angelicae Dahuricae decoct with water 3 times, each 2 hours, filter merging filtrate; Add ethanol in filtrate, make that concentration of alcohol reaches about 60% (V/V) in the filtrate, cold preservation 12 hours filters, and decompression filtrate recycling ethanol is to concentrated solution;

(4) with above-mentioned three kinds of filtrates, behind mixing, under 75 ℃ temperature, be concentrated into relative density and be 1.33～1.35 thick paste, add gelatin, make the unguentum that is used for external application.

Claims

1, a kind of drug regimen that is used for reducing swelling and alleviating pain is characterized in that it is made by following raw materials in weight:

2, a kind of drug regimen that is used for reducing swelling and alleviating pain as claimed in claim 1 is characterized in that it is to be made by the raw material of following weight:

33 parts in 25 parts of gelatin of 30 parts of Radixs Angelicae Dahuricae of Herba Violae.

3, a kind of drug regimen that is used for reducing swelling and alleviating pain as claimed in claim 2 is characterized in that the preparation technology of said preparation is:

(2) get Rhizoma Chuanxiong, Flos Carthami, Radix Angelicae Sinensis, Olibanum, Colophonium powder and be broken into coarse powder, according to the percolation under fluid extract and the extractum item (appendix I0 of Chinese Pharmacopoeia version in 2005), ethanol with 65～75% is made solvent, flood and carry out percolation (18～25 ℃) after 48-96 hour, with the speed of per minute 1～3ml percolation slowly, collect the about 800～1500ml of percolate, left standstill 24 hours, filter filtrate for later use;