CN101422240A - Human milk(containing first milk) freeze-drying powder production technique and products and use thereof - Google Patents
Human milk(containing first milk) freeze-drying powder production technique and products and use thereof Download PDFInfo
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- CN101422240A CN101422240A CNA2008100369646A CN200810036964A CN101422240A CN 101422240 A CN101422240 A CN 101422240A CN A2008100369646 A CNA2008100369646 A CN A2008100369646A CN 200810036964 A CN200810036964 A CN 200810036964A CN 101422240 A CN101422240 A CN 101422240A
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Abstract
The invention discloses a production technology of freeze-dried powder of breast milk (including colostrum) of human body, and a product and functions thereof. The production technology comprises the following steps: redundant breast milk (including colostrum) of healthy parturient women is collected; impurity removal by means of centrifugation, fat removal and pasteurization, freezing and drying at low temperature are carried out to obtain the freeze-dried powder of the breast milk (including colostrum) of human body. The freeze-dried powder can be made into tablets, capsules and oral solution; the freeze-dried powder can be adopted for supplying nutritious food required by lactation and growth for infants lack of breast feeding and teenagers in the growth stage, providing nutriments for athletes needing to create good results, personage in performing as well as film and television circles, personage succeeding in career, convalescents, subhealth crowd and crowd of various kinds of low immunity, and also can be used for curing all patients with tumors, people with AIDS, patients of organ transplantation and patients with diarrhea to speed up the recovery process of organism health, curing and avoiding exercise-induced diarrhea of athletes and improving the performance of sports; and the freeze-dried powder can further be used for anti-inflammation, sterilization and antivirus and providing special nutriments for cosmonauts, aviators and special forces.
Description
Technical field
The invention belongs to the utilization biotechnology with human mother's milk (containing colostrum), behind centrifugal, degreasing and sterilization, go cryodesiccated technical field again.Be particularly related to production technology and the goods and the effect of a kind of human mother's milk (containing colostrum) freeze-dried powder.
Background technology
Well-known, human mother's milk (containing colostrum) is the jewellery of human health, and it not only has abundant nutrition, but also contains special immunocyte.It is rare and precious, contained main nutrient composition is except active S-IgA (SigA), also be rich in the peroxidase (LP) of other multiple nutritional components as destroying pathogenic microorganisms, can in and the lactoferrin (Lf) of bacterium, can the sweet acid of antiviral list and unrighted acid and Oilgosaccharkdes, lysozyme, laticiferous cell etc.The proline polypeptide (PRP) that human mother's milk was rich in (containing colostrum) can make too active or blunt immune system response is tending towards normally promptly having two-way immunoloregulation function.Also contain in the human mother's milk (containing colostrum) and multiplely quicken and promote growth factor such as IGF (IGF), TGF (TGF), the EGF (EGF) that tissue growth is repaired and contain promising synthetic and repair the nucleotides that nucleic acid materials such as people's life nuclear power DNA and RNA are supplied raw materials.Its immunodominance is mainly reflected in the following aspects: cellular immunity aspect, humoral immunity aspect, growth factor aspect, viral infection resisting aspect.We are not difficult to find from domestic and international expert's research, have only just to contain the necessary nutrient of infant, immune antiboidy and steroid material in the human mother's milk (containing colostrum).The meaning of development and exploitation class breast milk product not only is supply infants, disease patient and the elderly of more weak and sickly to those, hypoimmunity and need to create elite, pilot, film ﹠ TV circles, model, white collar personage and all kinds of tumour patient, aids patient and the organ transplant patient of achievement, the process that the diarrhoea patient quickens the body health recovery; Treat and prevent sportsman's motility diarrhoea, raising sports achievement; Also can be used for anti-inflammatory, sterilization, antiviral and special procure nutrient, very profound significance is all arranged for astronaut, pilot, the soldier of special technical soldier provide.
The main component and the effect of human mother's milk (containing colostrum) see the following form:
At present, human mother's milk (containing colostrum) freeze-dried powder goods are used for effect of the present invention, Shang Weijian has report.
Summary of the invention
The invention provides a kind of human mother's milk (containing colostrum) freeze-drying powder production technique, its final purpose is in order to obtain human mother's milk (containing colostrum) freeze-dried powder and goods thereof.
A further object of the present invention is to protect the human mother's milk described in the invention effect of (containing colostrum).
In order to achieve the above object, the present invention adopts following technical scheme:
1, collects the unnecessary milk of healthy puerpera (containing unnecessary colostrum in 1～15 day), in collection process, can adopt inspection methods such as pH value, proportion, sense organ with control raw material quality.
2, centrifugal, in order to reach the purpose of removing impurity and fat better, described centrifugation step can be divided into for two steps, at first under 8～12 ℃, and with the speed of 600～800r/min centrifugal about 10 minutes, to remove impurity; Then under 30～40 ℃, with the speed of 2500～3000r/min centrifugal about 10 minutes, to remove impurity and fat; Also can be without centrifugal degreasing.
3, pasteurization, under 63.5 ℃, 30min is with killing microorganisms and virus for process;
4, freeze drying obtains human mother's milk (containing colostrum) freeze dried powder.
Can obtain human mother's milk (containing colostrum) freeze-dried powder by the inventive method.
Described a kind of human mother's milk (containing colostrum) goods.Comprise human mother's milk (the containing colostrum) freeze-dried powder and the additive that obtain by said method, its mass percent is respectively human mother's milk (containing colostrum) 1～99%, additive 1～99%, wherein said additive can be one of immunoglobulin (Ig), amino acid, Chinese herbal medicine, biologic product, all kinds of dairy products or its combination.In the described additive, the mass percent of each component can be all kinds of dairy products 5～85%, immunoglobulin (Ig) 0～15%, amino acid 0～15%, Chinese herbal medicine 0～15%, biologic product 0～15%.
Described immunoglobulin (Ig) can be IgA, IgG.Can be serotype, also can be secreting type.
Described amino acid can be one of Taurine, 18 kinds of essential amino acids or its combination.
Described Chinese herbal medicine can be genseng, the Radix Astragali, aloe, the fruit of Chinese wolfberry.Can be that former medicine also can be an extract.
Described biologic product can be all kinds of growth factors, two qi or Bacillus acidi lactici, antibiotic, antiviral drugs.
Described all kinds of dairy products can be colostrum pulvis, baby milk powder and animal/vegetable protein pulvis.
The additive formula of final products of the present invention is scientific and reasonable, and is with strong points.As Immunoglobulin IgA, IgG, show after deliberation with human mother's milk (containing colostrum) the freeze-dried powder antibacterial virus killing effect that acts synergistically and use apparently higher than folk prescription.Amino acid combines utilization to improving body immunity with human mother's milk (containing colostrum), gain in strength, and improves nerve conduction and visual performance plays an important role.The former medicine of Chinese herbal medicine genseng, the Radix Astragali, aloe, the fruit of Chinese wolfberry, particularly active component that therefrom extracts and human mother's milk (containing colostrum) freeze-dried powder prescription utilization, can significantly improve the activity of human natural killer cell (NK) cell and complement, strengthen neutrocyte or microphage phagocytic activity and killing action to virus, thereby improve the immunocompetence of body, the generation and the development of prevention and inhibition tumour.Research shows that also human mother's milk (containing colostrum) freeze-dried powder can to reduce drug dose, reduce antibiotic and antiviral (fungi preparation) infringement to people liver, renal function with all kinds of antibiotic and antiviral drugs synergy.Obviously the additive formula of final products of the present invention is scientific and reasonable, with strong points.
The specific embodiment
Freeze-drying powder production technique embodiment illustrates the present invention below in conjunction with human mother's milk (containing colostrum).Among this production technology embodiment, identical with following processing step.
Human mother's milk (containing colostrum) freeze-drying powder production technique may further comprise the steps:
1, gets the unnecessary colostrum of healthy puerpera, adopt inspection method control raw material quality such as pH value, proportion, sense organ;
2, centrifugal removal cell and fat;
3, pasteurization, under 63.5 ℃, through 30min, killing microorganisms and virus;
4, obtain human mother's milk (containing colostrum) freeze-dried powder after the freeze drying.
Can obtain human mother's milk (containing colostrum) freeze-dried powder by the foregoing description.
Human mother's milk (containing colostrum) freeze-dried powder goods embodiment.
Because above-mentioned production technology embodiment all can be used as the major ingredient of goods,, make goods by adding additive at this major ingredient as goods embodiment.Wherein said additive can be immunoglobulin (Ig), amino acid, Chinese herbal medicine, biologic product, all kinds of dairy products.Below tabulate human mother's milk (containing colostrum) freeze-dried powder goods for nine goods embodiment.
Table one
The final products additive of above-mentioned nine embodiment is scientific and reasonable, with strong points.
[annotating one] described immunoglobulin (Ig) can be IgA, IgG.Can be serotype, also can be secreting type.
[annotating two] described amino acid can be one of Taurine, 18 kinds of essential amino acids or its combination.
[annotating three] Chinese herbal medicine can be genseng, the Radix Astragali, aloe, the fruit of Chinese wolfberry.Can be that former medicine also can be an extract.
[annotating four] biologic product can be all kinds of growth factors, two qi or Bacillus acidi lactici, antibiotic, antiviral drugs.
[annotating five] described all kinds of dairy products can be colostrum pulvis, animal/vegetable protein pulvis.
Claims (12)
1, the production technology of a kind of human mother's milk (containing colostrum) freeze-dried powder comprises following processing step:
Collect the unnecessary colostrum of healthy puerpera;
Centrifugal decontamination, fat;
Pasteurization;
Freeze drying.
2, the production technology of human mother's milk according to claim 1 (containing colostrum) freeze-dried powder is characterized in that:
Describedly centrifugally remove impurity, fat was divided into for two steps, at first under 8～12 ℃, with 600～800r/min centrifugal 10 minutes, removed cell and impurity; And then under 30～40 ℃, removed degrease in centrifugal 10 minutes with 2500～3000r/min.Also can not slough fat and make it to become quality with whole milk powder.
3, the production technology of human mother's milk according to claim 1 and 2 (containing colostrum) freeze-dried powder is characterized in that:
The temperature of described pasteurization is 63.5 ℃, and the time is 30 minutes.
4, the production technology of human mother's milk according to claim 1 and 2 (containing colostrum) freeze-dried powder is characterized in that:
Described freeze drying process is the frozen drying method under adopting-40 ℃.
5, a kind of human mother's milk (containing colostrum) freeze-dried powder goods comprise human mother's milk (containing colostrum) freeze-dried powder (pure powder) and additive, it is characterized in that:
The described method of claim is made in described human colostrum (containing colostrum) freeze-dried powder (pure powder) the employing claim 1 to 4, described additive can be one of immunoglobulin (Ig), amino acid, Chinese herbal medicine, biologic product, all kinds of dairy products or its combination, its mass percent is respectively human mother's milk (containing colostrum) freeze-dried powder 1～99%, additive 1～99%.
6, human mother's milk according to claim 5 (containing colostrum) freeze-dried powder goods, it is characterized in that: described immunoglobulin (Ig) can be IgA, IgG; Can be serotype, also can be secreting type.
7, human colostrum according to claim 5 (containing colostrum) freeze-dried powder goods is characterized in that: described amino acid can be one of taurine or 18 kinds of essential amino acids or combination.
8, human mother's milk according to claim 5 (containing colostrum) freeze-dried powder goods, it is characterized in that: described Chinese herbal medicine can be genseng, the Radix Astragali, aloe, the fruit of Chinese wolfberry.Can be that former medicine also can be an extract.
9, human mother's milk according to claim 5 (containing colostrum) freeze-dried powder goods is characterized in that: described biologic product can all kinds of growth factors, two qi or Bacillus acidi lactici, antibiotic, antiviral drugs.
10, human mother's milk according to claim 5 (containing colostrum) freeze-dried powder goods is characterized in that: described all kinds of dairy products can be colostrum pulvis, baby milk powder and animal/vegetable protein pulvis.
11, human mother's milk according to claim 5 (containing colostrum) freeze-dried powder goods, it is characterized in that: in the described additive, the mass percent of each component is respectively immunoglobulin (Ig) 5～85%, amino acid 0～15%, Chinese herbal medicine 0～15%, biologic product 0～15%, all kinds of dairy products 0～15%.
12, human mother's milk according to claim 5 (containing colostrum) goods act as: can be used for providing lactation and the required nutriment of growth for lacking breastfeeding infant and being in the teenager of growth stage; The crowd who creates sportsman, the personage of performing art film ﹠ TV circles, achiever, convalescent and the sub-health population and all kinds of hypoimmunities of achievement for need provides the desired nutritional element; The process of also can be used for treating all kinds of tumour patients, aids patient and organ transplant patient, the patient that suffers from diarrhoea quickening the body health recovery; Treat and prevent sportsman's motility diarrhoea, raising sports achievement; Also can be used for anti-inflammatory, sterilization, antiviral and special procure nutrient for astronaut, pilot, the soldier of special technical soldier provide.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNA2008100369646A CN101422240A (en) | 2008-05-05 | 2008-05-05 | Human milk(containing first milk) freeze-drying powder production technique and products and use thereof |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNA2008100369646A CN101422240A (en) | 2008-05-05 | 2008-05-05 | Human milk(containing first milk) freeze-drying powder production technique and products and use thereof |
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| CN101422240A true CN101422240A (en) | 2009-05-06 |
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| Application Number | Title | Priority Date | Filing Date |
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| CNA2008100369646A Pending CN101422240A (en) | 2008-05-05 | 2008-05-05 | Human milk(containing first milk) freeze-drying powder production technique and products and use thereof |
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Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102429031A (en) * | 2011-11-01 | 2012-05-02 | 张明 | Method for producing freeze-dried whole donkey milk powder |
| CN105994651A (en) * | 2016-06-05 | 2016-10-12 | 青海金祁连乳业有限责任公司 | Preparation technology capable of preserving active nutrients in milk powder |
| CN106455599A (en) * | 2014-06-16 | 2017-02-22 | 卡拉格股份公司 | Method and apparatus for preparation of human milk to be stored |
| CN110075054A (en) * | 2019-06-06 | 2019-08-02 | 山东天源人乳库科技发展有限公司 | A kind of humanized's growth factor preparation for repairing and preparation method thereof from human milk |
-
2008
- 2008-05-05 CN CNA2008100369646A patent/CN101422240A/en active Pending
Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102429031A (en) * | 2011-11-01 | 2012-05-02 | 张明 | Method for producing freeze-dried whole donkey milk powder |
| CN106455599A (en) * | 2014-06-16 | 2017-02-22 | 卡拉格股份公司 | Method and apparatus for preparation of human milk to be stored |
| CN106455599B (en) * | 2014-06-16 | 2020-04-28 | 卡拉格股份公司 | Method and apparatus for preparing human milk for storage |
| CN105994651A (en) * | 2016-06-05 | 2016-10-12 | 青海金祁连乳业有限责任公司 | Preparation technology capable of preserving active nutrients in milk powder |
| CN110075054A (en) * | 2019-06-06 | 2019-08-02 | 山东天源人乳库科技发展有限公司 | A kind of humanized's growth factor preparation for repairing and preparation method thereof from human milk |
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Open date: 20090506 |