CN101332309A - 水溶性多糖类复合医用敷料及制备方法 - Google Patents
水溶性多糖类复合医用敷料及制备方法 Download PDFInfo
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- CN101332309A CN101332309A CNA2006100009355A CN200610000935A CN101332309A CN 101332309 A CN101332309 A CN 101332309A CN A2006100009355 A CNA2006100009355 A CN A2006100009355A CN 200610000935 A CN200610000935 A CN 200610000935A CN 101332309 A CN101332309 A CN 101332309A
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- Prior art keywords
- water
- soluble
- medical dressing
- polyose
- polysaccharide
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- 238000002360 preparation method Methods 0.000 title claims abstract description 15
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 title claims description 47
- 239000002131 composite material Substances 0.000 title claims description 23
- 229920001282 polysaccharide Polymers 0.000 claims abstract description 47
- 239000005017 polysaccharide Substances 0.000 claims abstract description 47
- 150000004676 glycans Chemical class 0.000 claims abstract description 46
- 229920001661 Chitosan Polymers 0.000 claims abstract description 17
- 229920002101 Chitin Polymers 0.000 claims abstract description 16
- 229920002678 cellulose Polymers 0.000 claims abstract description 14
- 239000001913 cellulose Substances 0.000 claims abstract description 14
- 230000000844 anti-bacterial effect Effects 0.000 claims abstract description 8
- 150000001875 compounds Chemical class 0.000 claims abstract description 7
- 239000000463 material Substances 0.000 claims abstract description 7
- IXPNQXFRVYWDDI-UHFFFAOYSA-N 1-methyl-2,4-dioxo-1,3-diazinane-5-carboximidamide Chemical compound CN1CC(C(N)=N)C(=O)NC1=O IXPNQXFRVYWDDI-UHFFFAOYSA-N 0.000 claims abstract description 5
- 235000010413 sodium alginate Nutrition 0.000 claims abstract description 5
- 239000000661 sodium alginate Substances 0.000 claims abstract description 5
- 229940005550 sodium alginate Drugs 0.000 claims abstract description 5
- 239000004744 fabric Substances 0.000 claims description 14
- 235000013311 vegetables Nutrition 0.000 claims description 14
- 239000004745 nonwoven fabric Substances 0.000 claims description 10
- 239000000843 powder Substances 0.000 claims description 9
- 239000000443 aerosol Substances 0.000 claims description 7
- 239000000835 fiber Substances 0.000 claims description 7
- HEMHJVSKTPXQMS-UHFFFAOYSA-M Sodium hydroxide Chemical compound [OH-].[Na+] HEMHJVSKTPXQMS-UHFFFAOYSA-M 0.000 claims description 6
- 238000006243 chemical reaction Methods 0.000 claims description 5
- 239000003292 glue Substances 0.000 claims description 4
- 239000011259 mixed solution Substances 0.000 claims description 4
- 239000003960 organic solvent Substances 0.000 claims description 4
- 239000003380 propellant Substances 0.000 claims description 4
- 239000000725 suspension Substances 0.000 claims description 4
- 230000032050 esterification Effects 0.000 claims description 3
- 238000005886 esterification reaction Methods 0.000 claims description 3
- 238000004108 freeze drying Methods 0.000 claims description 3
- 239000000243 solution Substances 0.000 claims description 3
- KIUKXJAPPMFGSW-DNGZLQJQSA-N (2S,3S,4S,5R,6R)-6-[(2S,3R,4R,5S,6R)-3-Acetamido-2-[(2S,3S,4R,5R,6R)-6-[(2R,3R,4R,5S,6R)-3-acetamido-2,5-dihydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-2-carboxy-4,5-dihydroxyoxan-3-yl]oxy-5-hydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-3,4,5-trihydroxyoxane-2-carboxylic acid Chemical compound CC(=O)N[C@H]1[C@H](O)O[C@H](CO)[C@@H](O)[C@@H]1O[C@H]1[C@H](O)[C@@H](O)[C@H](O[C@H]2[C@@H]([C@@H](O[C@H]3[C@@H]([C@@H](O)[C@H](O)[C@H](O3)C(O)=O)O)[C@H](O)[C@@H](CO)O2)NC(C)=O)[C@@H](C(O)=O)O1 KIUKXJAPPMFGSW-DNGZLQJQSA-N 0.000 claims description 2
- 230000015572 biosynthetic process Effects 0.000 claims description 2
- 239000011521 glass Substances 0.000 claims description 2
- 229920002674 hyaluronan Polymers 0.000 claims description 2
- 229960003160 hyaluronic acid Drugs 0.000 claims description 2
- 239000012535 impurity Substances 0.000 claims description 2
- 238000001802 infusion Methods 0.000 claims description 2
- 238000000034 method Methods 0.000 claims description 2
- 239000000203 mixture Substances 0.000 claims description 2
- 150000007524 organic acids Chemical class 0.000 claims description 2
- 238000003825 pressing Methods 0.000 claims description 2
- 238000001291 vacuum drying Methods 0.000 claims description 2
- 239000004627 regenerated cellulose Substances 0.000 claims 1
- 239000007921 spray Substances 0.000 claims 1
- -1 polysaccharide compound Chemical class 0.000 abstract description 2
- 230000004913 activation Effects 0.000 abstract 3
- 239000004599 antimicrobial Substances 0.000 abstract 1
- 230000023597 hemostasis Effects 0.000 description 6
- DGAQECJNVWCQMB-PUAWFVPOSA-M Ilexoside XXIX Chemical compound C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C@@H](C5(C)C)OS(=O)(=O)[O-])C)C)[C@@H]2[C@]1(C)O)C)C(=O)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)CO)O)O)O.[Na+] DGAQECJNVWCQMB-PUAWFVPOSA-M 0.000 description 5
- 229910052708 sodium Inorganic materials 0.000 description 5
- 239000011734 sodium Substances 0.000 description 5
- QTBSBXVTEAMEQO-UHFFFAOYSA-N Acetic acid Chemical compound CC(O)=O QTBSBXVTEAMEQO-UHFFFAOYSA-N 0.000 description 3
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 3
- 208000027418 Wounds and injury Diseases 0.000 description 3
- 230000003115 biocidal effect Effects 0.000 description 3
- 125000002057 carboxymethyl group Chemical group [H]OC(=O)C([H])([H])[*] 0.000 description 3
- 239000000047 product Substances 0.000 description 3
- 238000010521 absorption reaction Methods 0.000 description 2
- 239000000084 colloidal system Substances 0.000 description 2
- 230000007812 deficiency Effects 0.000 description 2
- 239000012467 final product Substances 0.000 description 2
- 208000015181 infectious disease Diseases 0.000 description 2
- AQLLBJAXUCIJSR-UHFFFAOYSA-N OC(=O)C[Na] Chemical compound OC(=O)C[Na] AQLLBJAXUCIJSR-UHFFFAOYSA-N 0.000 description 1
- 229920000297 Rayon Polymers 0.000 description 1
- 239000007864 aqueous solution Substances 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 230000000295 complement effect Effects 0.000 description 1
- 201000010099 disease Diseases 0.000 description 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 1
- 239000002552 dosage form Substances 0.000 description 1
- 239000003814 drug Substances 0.000 description 1
- 230000000694 effects Effects 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 238000006266 etherification reaction Methods 0.000 description 1
- 210000000416 exudates and transudate Anatomy 0.000 description 1
- 230000035876 healing Effects 0.000 description 1
- 208000014674 injury Diseases 0.000 description 1
- 238000007639 printing Methods 0.000 description 1
- 238000007789 sealing Methods 0.000 description 1
- FDRCDNZGSXJAFP-UHFFFAOYSA-M sodium chloroacetate Chemical compound [Na+].[O-]C(=O)CCl FDRCDNZGSXJAFP-UHFFFAOYSA-M 0.000 description 1
- 230000000638 stimulation Effects 0.000 description 1
- 230000008733 trauma Effects 0.000 description 1
- 238000005406 washing Methods 0.000 description 1
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- Materials For Medical Uses (AREA)
Abstract
Description
Claims (11)
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN2006100009355A CN101332309B (zh) | 2006-01-12 | 2006-01-12 | 水溶性多糖类复合医用敷料及制备方法 |
Applications Claiming Priority (1)
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CN2006100009355A CN101332309B (zh) | 2006-01-12 | 2006-01-12 | 水溶性多糖类复合医用敷料及制备方法 |
Publications (2)
Publication Number | Publication Date |
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CN101332309A true CN101332309A (zh) | 2008-12-31 |
CN101332309B CN101332309B (zh) | 2012-11-14 |
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CN2006100009355A Active CN101332309B (zh) | 2006-01-12 | 2006-01-12 | 水溶性多糖类复合医用敷料及制备方法 |
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Cited By (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN101905034A (zh) * | 2010-07-19 | 2010-12-08 | 武汉理工大学 | 生物多糖自组装修饰的壳聚糖抗菌生物材料的制备方法 |
CN102335451A (zh) * | 2011-09-15 | 2012-02-01 | 德州海利安生物科技股份有限公司 | 一种抑菌促愈合功能的医用胶体敷料及其应用 |
CN103061109A (zh) * | 2012-12-14 | 2013-04-24 | 青岛海蓝生物制品有限公司 | 非水溶性壳聚糖纤维改性成水溶性壳聚糖纤维的方法 |
CN103656730A (zh) * | 2013-12-10 | 2014-03-26 | 徐花 | 一种医用壳聚糖敷料 |
CN103705971A (zh) * | 2013-12-19 | 2014-04-09 | 褚加冕 | 一种复合透明质酸伤口敷料 |
CN104324413A (zh) * | 2014-11-10 | 2015-02-04 | 华玉叶 | 一种水凝胶敷料的制备方法 |
CN107233617A (zh) * | 2017-06-05 | 2017-10-10 | 浙江工业大学 | 一种液体壳聚糖创伤敷料及其制备与应用 |
WO2019071587A1 (en) * | 2017-10-13 | 2019-04-18 | Gunze Limited | BIOLOGICAL TISSUE REINFORCING MATERIAL KIT AND BIOLOGICAL TISSUE REINFORCING MATERIAL |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN1297957A (zh) * | 1999-12-01 | 2001-06-06 | 武汉大学 | 羧甲基壳聚糖和海藻酸共混膜或纤维的制备方法及其用途 |
CN1120198C (zh) * | 2001-04-30 | 2003-09-03 | 武汉大学 | 甲壳素/纤维素共混膜或纤维材料及其制法和用途 |
CN1332081C (zh) * | 2005-04-27 | 2007-08-15 | 武汉大学 | 海藻酸钠/水溶性甲壳素共混纤维及其制备方法和用途 |
-
2006
- 2006-01-12 CN CN2006100009355A patent/CN101332309B/zh active Active
Cited By (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN101905034A (zh) * | 2010-07-19 | 2010-12-08 | 武汉理工大学 | 生物多糖自组装修饰的壳聚糖抗菌生物材料的制备方法 |
CN101905034B (zh) * | 2010-07-19 | 2013-06-12 | 武汉理工大学 | 生物多糖自组装修饰的壳聚糖抗菌生物材料的制备方法 |
CN102335451A (zh) * | 2011-09-15 | 2012-02-01 | 德州海利安生物科技股份有限公司 | 一种抑菌促愈合功能的医用胶体敷料及其应用 |
CN103061109A (zh) * | 2012-12-14 | 2013-04-24 | 青岛海蓝生物制品有限公司 | 非水溶性壳聚糖纤维改性成水溶性壳聚糖纤维的方法 |
CN103061109B (zh) * | 2012-12-14 | 2016-03-02 | 青岛海蓝生物制品有限公司 | 非水溶性壳聚糖纤维改性成水溶性壳聚糖纤维的方法 |
CN103656730A (zh) * | 2013-12-10 | 2014-03-26 | 徐花 | 一种医用壳聚糖敷料 |
CN103705971A (zh) * | 2013-12-19 | 2014-04-09 | 褚加冕 | 一种复合透明质酸伤口敷料 |
CN103705971B (zh) * | 2013-12-19 | 2016-01-20 | 褚加冕 | 一种复合透明质酸伤口敷料 |
CN104324413A (zh) * | 2014-11-10 | 2015-02-04 | 华玉叶 | 一种水凝胶敷料的制备方法 |
CN107233617A (zh) * | 2017-06-05 | 2017-10-10 | 浙江工业大学 | 一种液体壳聚糖创伤敷料及其制备与应用 |
WO2019071587A1 (en) * | 2017-10-13 | 2019-04-18 | Gunze Limited | BIOLOGICAL TISSUE REINFORCING MATERIAL KIT AND BIOLOGICAL TISSUE REINFORCING MATERIAL |
Also Published As
Publication number | Publication date |
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CN101332309B (zh) | 2012-11-14 |
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ASS | Succession or assignment of patent right |
Owner name: BEIJING TAIKE SIMAN TECHNOLOGICAL TECHNOLOGY CO., Free format text: FORMER OWNER: ZHANG MEI Effective date: 20140321 |
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C41 | Transfer of patent application or patent right or utility model | ||
COR | Change of bibliographic data |
Free format text: CORRECT: ADDRESS; FROM: 100062 CHONGWEN, BEIJING TO: 101304 SHUNYI, BEIJING |
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TR01 | Transfer of patent right |
Effective date of registration: 20140321 Address after: 101304 Beijing city Shunyi District Li Qiao Zhen Li Li Road Bridge No. 5 Patentee after: Beijing Taikesiman Technology Development Co. Ltd. Address before: 100062 Beijing city Chongwen District South East market in East No. 3 Building 1 No. 401 Patentee before: Zhang Mei |
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C53 | Correction of patent for invention or patent application | ||
CB03 | Change of inventor or designer information |
Inventor after: Zhang Mei Inventor after: Zhang Jinyu Inventor before: Zhang Mei |
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COR | Change of bibliographic data |
Free format text: CORRECT: INVENTOR; FROM: ZHANG MEI TO: ZHANG MEI ZHANG JINYU |