CN101095842A - Chinese medicine composition for treating diabetes - Google Patents

Abstract

The invention relates to a Chinese medicinal combination for treating diabetes which is prepared from more than ten kinds of Chinese medicinal herbs including Dendrobium nobile, kudzu vine root, rehmannia root and root of Chinese trichosannthes. The medicament has the advantages of assured curative effect, safe and convenient application, no toxic and side effects, and low price.

Description

A kind of Chinese medicine composition for the treatment of diabetes

Technical field

The present invention relates to a kind of Chinese medicine composition for the treatment of diabetes, is that a kind of diabetes for the treatment of are the Chinese medicine composition of raw material with the Chinese herbal medicine.Belong to the field of Chinese medicines.

Background technology

Diabetes are ancient disease, and just there is being certain understanding in many countries between east and west to it a long time ago.Now, one of the cardiovascular and cerebrovascular disease that continues, tumor subsequent great epidemic diseases have been become more.Because the seriousness of its complication has caused global medical science circle and World Health Organization (WHO) and the public's serious concern.Chinese Medicine scholar has rich experience to diabetes control.Tradition doctor's nationality all carries the theory and the therapy of having recorded this respect as " interior warp ", " Medical Treasures of the Golden Chamber ", " prescriptions worth thousand gold " and " medical secrets of official " etc.; Belong to sick category such as " quenching one's thirst ", " diseases due to endogenous heat of ZANG FU organs " substantially.7th century of the Christian era Zhen Quan of Tang work " recording proved recipe at all times ", 50 volumes have been narrated primary disease " thirsty and drinking a lot of water, frequent micturition, no fat be bran flakes seemingly, sweet person, all diabetes also ".Diabetes are a kind of common incretion metabolism diseases.According to WHO prediction, 21 century diabetes will be popular in developing country, will be to world diabetes patient in 2005 above 200,000,000.The present non-insulin-dependent diabetes mellitus prevalence of China is 3.22%, the impaired glucose tolerance person reaches 4.72%, and the diabetes annual morbidity is 1,30/,100,000, increases by 3 times in nearly 5 years, China suffers from the diabetes number at present and surpasses 3,500 ten thousand, the edge crowd who still has fifty-five million not made a definite diagnosis.China's new trouble diabetes number every year, every day, diabetes became the heavy burden of society and household economy with 3500 people's speed increase with 1,250,000, and the study on prevention of actively developing diabetes is an important topic in China's sanitary work.The traditional Chinese medical science is divided clinically and disease type Coryza Treated by Syndrome Differentiation such as is stopped in dryness-heat being excessive in the interior, deficiency of both QI and YIN, stagnation of QI and blood, deficiency of both YIN and YANG, damp-heat gluing each other, the pathogenic water, obtains very good effect.Invent a kind of not only safety but also effective Chinese medicine preparation, be significant.

Summary of the invention

The present invention develops in conjunction with the latest modern technological scientific achievement on the basis of traditional tcm syndrome differentiation and treatment.The purpose of this invention is to provide a kind of Chinese medicine composition for the treatment of diabetes.Have determined curative effect, safe ready, have no side effect, cheap characteristics.

The present invention is made by the following weight proportion raw material:

1.0～4 parts of 1.0～4 parts of Radix Ophiopogonis of 1.5～6 parts of Poria of Cortex Lycii

1.0～4 parts of 1.0～4 parts of Fructus Corni of 1.5～6 parts of Radix Puerariaes of Cortex Mori

0.1～2 part of 1.0～4 portions of Semen Plantaginis of 1.5～6 parts of Rhizoma Polygonatis of Radix Rehmanniae

0.1～1 part of 0.1～2 part of Radix Trichosanthis of 0.1～2 part of Herba Dendrobii of Rhizoma Coptidis.

The weight proportion of each raw material of optimization formula of the present invention is:

1.5～2.5 parts of 1.5～2.5 parts of Radix Ophiopogonis of 2.5～3.5 parts of Poria of Cortex Lycii

1.5～2.5 parts of 1.5～2.5 parts of Fructus Corni of 2.5～3.5 parts of Radix Puerariaes of Cortex Mori

0.5～1.5 part of 1.5～2.5 portions of Semen Plantaginis of 2.5～3.5 parts of Rhizoma Polygonatis of Radix Rehmanniae

0.3～0.7 part of 0.5～1.5 part of Radix Trichosanthis of 0.5～1.5 part of Herba Dendrobii of Rhizoma Coptidis.

The weight proportion of each raw material of optimum formula of the present invention is:

2 parts of 2 parts of Radix Ophiopogonis of 3 parts of Poria of Cortex Lycii

2 parts of 2 parts of Fructus Corni of 3 parts of Radix Puerariaes of Cortex Mori

1 part of 2 portions of Semen Plantaginis of 3 parts of Rhizoma Polygonatis of Radix Rehmanniae

0.5 part of 1 part of Radix Trichosanthis of 1 part of Herba Dendrobii of Rhizoma Coptidis.

Drug action mechanism among the present invention is as follows:

The Cortex Lycii property of medicine is sweet, and is cold.Return lung, kidney channel.Has clearind deficient heat, purte the white, the effect of removing heat from blood.Can treat hectic fever due to deficiency of YIN, hectic fever due to YIN-deficiency night sweat, the infantile malnutrition heating, dyspnea and cough due to lung-heat, haematemesis, epistaxis, hematuria are quenched one's thirst etc.(the 1141st page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).

The Cortex Mori nature and flavor are sweet, hot, and are cold.Return lung, spleen channel.Has eliminating pathogen from the lung for relieving asthma, the effect of inducing diuresis to remove edema.Cure mainly the fullness in the chest that lung-heat or diseases caused by retention of fluid stop lung and breath with cough hemoptysis, edema, beriberi, dysuria etc.(the 2787th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).

The Radix Rehmanniae nature and flavor are sweet, cold.GUIXIN, liver, kidney channel.Has clearing away heat and cooling blood, yin nourishing, the effect of promoting the production of body fluid.Can treat that calentura crimson tongue excessive thirst, interior-heat caused by deficiency of YIN, hectic fever due to YIN-deficiency consumptive fever, interior-heat are quenched one's thirst, haematemesis, epistaxis, send out speckle dermexanthesis etc.(Ji Yubin chief editor " Chinese medicine medicine for preventing pharmacology and application " Heilungkiang science tech publishing house 1999 version the 514th page).

The Poria property of medicine is sweet, light, and is flat.GUIXIN, spleen, lung, kidney channel.Has promoting diuresis to eliminate damp pathogen, invigorating the spleen and regulating the stomach, the effect of mind tranquilizing and the heart calming.Can treat dysuria, the edema distension, is had loose bowels at phlegm retention cough with dyspnea, vomiting, insufficiency of the spleen lack of appetite, palpitation and restlessness, insomnia forgetfulness, seminal emission nebulousurine etc.(the 2154th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).

The Radix Puerariae property of medicine is sweet, hot, and is flat.Return spleen, stomach warp.Have expelling pathogenic factors from muscles and deliver, promoting the production of body fluid to quench thirst, yang invigorating antidiarrheal effect.Cure mainly fever caused by exogenous pathogens, rigidity pain on the head and nape, measles goes out not smooth from the beginning of, rash, and pestilence is thirsty, and diabetes is had loose bowels, dysentery etc.(the 3209th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).

The Rhizoma Polygonati property of medicine is sweet, and is flat.Return spleen, lung, kidney channel.Has nourishing YIN and moistening the lung, invigorating the spleen and replenishing QI, the effect of nourishing kidney replenishing essence.Can treat deficiency of YIN chronic cough, the xeropulmonary cough; Insufficiency of the spleen weak, the lack of appetite xerostomia is quenched one's thirst; The deficiency of the kidney soreness of the waist and knees, impotence and seminal emission, the tinnitus order is dark, early whitening of beard and hair, the body weakness with emaciation is thin, wind favus disease etc.(the 2830th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).

Sweet, the little hardship of the Radix Ophiopogonis property of medicine is slightly cold.Return lung, stomach, heart channel.Has nourishing YIN and moistening the lung, nourishing the stomach to promote the production of body fluid, the effect of the relieving restlessness that clears away heart-fire.Can treat dryness of the lung dry cough, lung abscess, deficiency of YIN chronic cough, Tianjin wound is thirsty, quenches one's thirst, and vexed insomnia is had sore throat, the dryness of the intestine constipation, heat in blood is told nosebleed etc.(the 1430th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).

The acid of the Fructus Corni property of medicine, tepor.Return liver, kidney channel.Has liver and kidney tonifying, the effect that convergence is taken off admittedly.Can treat and have a dizzy spell, deafness and tinnitus, soreness of the waist and knees, emission and spermatorrhea, frequent micturition, incessant sweating due to debility, woman uterine bleeding etc.(the 248th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).

The Semen Plantaginis property of medicine is sweet, light, is slightly cold.Return lung, liver, kidney, urinary bladder channel.Have heat clearing away, diuresis makes eye bright, the expectorant effect.Can treat urinary obstruction, stranguria with turbid discharge, leukorrhagia, edema, the heat-damp in summer dysentery, conjunctival congestion is hidden from view, and the expectorant heat syndrome cough is breathed heavily etc.(the 539th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).

Rhizoma Coptidis nature and flavor hardship, cold.GUIXIN, liver, stomach, large intestine channel.Has clearing away heat-fire, dampness, antidotal effect.Cure mainly the calentura heresy and go into the hyperpyrexia of heart channel, agitation, delirium or the absurd row of intenseness of heat forcing blood tell nosebleed, the damp and hot feeling of stuffiness in chest is had loose bowels, dysentery, the vexed insomnia of hyperactivity of heart-fire, gastropyretic vomiting, rapid digestion of food and polyorexia, liver-fire conjunctival congestion and swelling pain, and pathopyretic ulcer are treated malicious septicemia, gingival swelling and pain, aphtha of the mouth and tongue, hemorrhoidal bleeding, eczema is scalded etc.(the 2818th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).

The Herba Dendrobii nature and flavor are sweet, are slightly cold.Return stomach, kidney channel.Has reinforcing stomach reg fluid, the effect of nourishing YIN and clearing away heat.Can treat cloudy impairment of body fluid and lose, the xerostomia excessive thirst, lack of appetite is retched, deficiency-heat after being ill, poor vision etc.(the 70th page of Chemical Industry Press of Pharmacopoeia of the People's Republic of China version in 2000 is compiled by Chinese Pharmacopoeia Commission).

Sweet, the little hardship of the Radix Trichosanthis property of medicine is slightly cold.Attach to the lung and stomach meridians.Has clearing away heat and promoting production of body fluid, moistening the lung and resolving phlegm, the effect of detumescence and apocenosis.It is thirsty to treat calentura, the polydipsia of quenching one's thirst, lung-heat type cough, sore swollen toxin etc.(the 443rd page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).

The present invention follows the principles of formulating prescriptions of the traditional Chinese medical science " monarch ", is monarch drug with Cortex Lycii, Cortex Mori, Radix Rehmanniae and Radix Trichosanthis; With Poria, Radix Puerariae, Rhizoma Polygonati, Radix Ophiopogonis and Fructus Corni is ministerial drug; With Semen Plantaginis, Rhizoma Coptidis and Herba Dendrobii is adjuvant.All medicines are harmonious, and are total to the tool clearing away heat-fire, the effect of promoting the production of body fluid and moisturizing.The treatment diabetes have determined curative effect, have no side effect taking convenience, cheap characteristics.

Clinical drug of the present invention uses the result to show that following advantage is arranged:

1, the Chinese herbal medicine each component selected for use of the present invention meets the regulation of Pharmacopoeia of People's Republic of China, utilizes the comprehensive function treatment diabetes of the Chinese medicine of respectively distinguishing the flavor of, and is nontoxic to human body.Show that through the acute and chronic toxicity test of animal the animal of being tested does not see any toxic reaction, its main organs does not have tangible change yet, and safety of medicine is reliable.

2, rich in proteins in the medicine of the present invention, glucose, glucuronic acid, volatile oil, pectin, fructose, organic acid, lecithin, vitamin, aminoacid also contains various trace elements such as Saponin, plant sterol and calcium, is beneficial to absorption of human body, health invigorating.

3, the present invention not only can effectively treat diabetes, and the prevention of diabetes is also had good effect, and the treatment diabetes have determined curative effect, have no side effect taking convenience, cheap characteristics.

For showing medicine of the present invention, as follows through clinical test results to treatment treatment of diabetes effect; Treatment diabetics 20 examples.Take the embodiment decoction, each 1 bag, two to three times on the one, take half an hour ante cibum.Three months is a course of treatment, take continuously three the course of treatment observe the curative effect.8 examples of fully recovering account for 40%, and 9 examples that take a turn for the better account for 45%, and invalid 3 examples account for 15%, and total effective rate reaches 85%.After three course of therapy, patient does not have any untoward reaction, and three big routine tests and hepatic and renal function detect no abnormal.

The specific embodiment

The embodiment decoction takes by weighing raw material by following weight:

2 parts of 2 parts of Radix Ophiopogonis of 3 parts of Poria of Cortex Lycii

2 parts of 2 parts of Fructus Corni of 3 parts of Radix Puerariaes of Cortex Mori

1 part of 2 portions of Semen Plantaginis of 3 parts of Rhizoma Polygonatis of Radix Rehmanniae

0.5 part of 1 part of Radix Trichosanthis of 1 part of Herba Dendrobii of Rhizoma Coptidis.

Preparation method is to get above-mentioned raw materials to clean roguing, dries, and is ground into granule, soaks 1 hour, puts and decocts with water secondary in the multi-function extractor, adds up the water of 10 times of amounts of medical material for the first time, decocts 1.5～2 hours, gets decocting liquid, filters.Add up for the second time the water of 7 times of amounts of medical material, decocted 1～1.2 hour, get decocting liquid twice, filter, in the heat-sealing bag, 105 ℃ of high temperature sterilizes, packing is promptly.The decoction of the treatment diabetes that the present invention makes is that plastic packaging is packed, and every bag of 210ml is oral, one time one bag, every day two to three times.Three months is a course of treatment.

Claims (3)

1, a kind of Chinese medicine composition for the treatment of diabetes is characterized in that it is made by the following weight proportion raw material:

1.0～4 parts of 1.0～4 parts of Radix Ophiopogonis of 1.5～6 parts of Poria of Cortex Lycii

1.0～4 parts of 1.0～4 parts of Fructus Corni of 1.5～6 parts of Radix Puerariaes of Cortex Mori

0.1～2 part of 1.0～4 portions of Semen Plantaginis of 1.5～6 parts of Rhizoma Polygonatis of Radix Rehmanniae

0.1～1 part of 0.1～2 part of Radix Trichosanthis of 0.1～2 part of Herba Dendrobii of Rhizoma Coptidis.

2, a kind of Chinese medicine composition for the treatment of diabetes according to claim 1, wherein the weight proportion of each raw material is:

1.5～2.5 parts of 1.5～2.5 parts of Radix Ophiopogonis of 2.5～3.5 parts of Poria of Cortex Lycii

1.5～2.5 parts of 1.5～2.5 parts of Fructus Corni of 2.5～3.5 parts of Radix Puerariaes of Cortex Mori

0.5～1.5 part of 1.5～2.5 portions of Semen Plantaginis of 2.5～3.5 parts of Rhizoma Polygonatis of Radix Rehmanniae

0.3～0.7 part of 0.5～1.5 part of Radix Trichosanthis of 0.5～1.5 part of Herba Dendrobii of Rhizoma Coptidis.

3, a kind of Chinese medicine composition for the treatment of diabetes according to claim 1, wherein the weight proportion of each raw material is:

2 parts of 2 parts of Radix Ophiopogonis of 3 parts of Poria of Cortex Lycii

2 parts of 2 parts of Fructus Corni of 3 parts of Radix Puerariaes of Cortex Mori

1 part of 2 portions of Semen Plantaginis of 3 parts of Rhizoma Polygonatis of Radix Rehmanniae

0.5 part of 1 part of Radix Trichosanthis of 1 part of Herba Dendrobii of Rhizoma Coptidis.