CN101040936A - Compound Chinese traditional medicine agent for preventing fish verminosis - Google Patents
Compound Chinese traditional medicine agent for preventing fish verminosis Download PDFInfo
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- CN101040936A CN101040936A CNA2007100111305A CN200710011130A CN101040936A CN 101040936 A CN101040936 A CN 101040936A CN A2007100111305 A CNA2007100111305 A CN A2007100111305A CN 200710011130 A CN200710011130 A CN 200710011130A CN 101040936 A CN101040936 A CN 101040936A
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Abstract
The invention discloses a compound Chinese medicinal herbal preparation for the prevention and treatment of fish parasitic diseases, wherein the constituents include (by weight percent) pomegranate bark 15-25%, kuh-seng 15-25%, toosendan fruit 12-18%, cinnamon twig 8-12%, sweet wormwood 8-12%, garden burnet root 8-12% and baikal skullcap root 12-18%.
Description
Technical field:
The present invention relates to a kind of Chinese medicine formula, especially a kind of being applied in the fish culture, the Chinese medicine formula of control eliminating fish parasites disease.
Background technology:
In the fish culture process, parasitic disease such as trichodinasis, chilodoniasis are one of more common diseases.Trichodina and oblique tube insect colonize on the body surface and the gill of fish, and quantity is little to the fish influence after a little while, but a large amount of parasitism then causes disease, destroy body surface and gill tissue, and stimulate the fish body to produce a large amount of mucus, make fish lose the ability of moving about and can not prey on, breathing is obstructed, and the fish body is become thin, and finally dies of exhaustion.Simultaneously, be subjected to the also easy secondary bacterial disease of fish of these two kinds of parasitic infestations, form parasite and bacteroidal complication.The reproduction speed of Trichodina, oblique tube insect is surprising in addition, and internal energy propagation was tens times in one day, and parasitic in the middle of need not, infection velocity is fast in population, can break out rapidly, and is serious to fish culture harm.
At present, all be to adopt copper sulfate, mixture of ferrous sulfate to handle for the prevention of eliminating fish parasites disease and treatment, with copper sulfate and ferrous sulfate (5: 2) mixture 0.7 gram full pool spilling head, also can singly use copper sulfate (0.8 gram/rice as every cubic metre of water body
3) full pool spilling head.Though, insecticidal effect is obvious, but but there are the following problems: the excessive meeting of copper sulfate causes that the necrosis of Fish nephridial tissue, hemopoietic tissue destroy, liver fat increases, also may remain in simultaneously in the gill, muscle regulating liver-QI of Fish, hinder the absorption of intestinal, thereby influence ingesting and growing of Fish, so can not often use.Some fishing ground is to add copper sulfate or organophosphor processing trichodinasis with potassium permanganate, though certain effect is arranged, not really desirable.Simultaneously, also can make the fish inappetence, destroy the quality of the flesh of fish, influence growth and the immunity of fish, reduce the resistance of fish other diseases.In addition, chemical agent (copper sulfate etc.) the also fragmentation effect to algae is remarkable, makes the main source of dissolved oxygen in the breeding water body---and algae lacks, and also can influence the pH value of breeding water simultaneously, and is bigger to the breeding environment influence;
Summary of the invention:
The present invention is in order to solve existing in prior technology the problems referred to above, a kind of employing natural Chinese medicinal herb is provided, its digestion liquid can effectively kill fish body parasite, has no side effect, the Chinese medicine formula of non-corrosiveness, the control eliminating fish parasites disease of safe in utilization, pollution-free to water environment, orthobiosis of not influencing Fish.
Technical solution of the present invention is: a kind of Chinese medicine formula of preventing and treating the eliminating fish parasites disease is characterized in that each weight percentages of components is as follows:
Pericarpium Granati 15～25%
Radix Sophorae Flavescentis 15～25%
Fructus Toosendan 12～18%
Ramulus Cinnamomi 8～12%
Herba Artemisiae Annuae 8～12%
Radix Sanguisorbae 8～12%
Radix Scutellariae 12～18%.
The optimum weight percentage ratio of each component is as follows:
Pericarpium Granati 20%
Radix Sophorae Flavescentis 20%
Fructus Toosendan 15%
Ramulus Cinnamomi 15%
Herba Artemisiae Annuae 10%
Radix Sanguisorbae 10%
Radix Scutellariae 15%.
Main efficacy of drugs is as follows:
Pericarpium Granati is the peel of Punicaceae machaka or dungarunga Punica granatum L..All there is cultivation in the most of area of China, and peel contains tannin, resin, mannitol, natural gum, gallic acid and malic acid etc.Cure mainly the deficiency and coldness chronic diarrhea, enteritis, dysentery, taeniasis, ascariasis.Suitable amount used externally is controlled otitis media, controls acute enteritis.Also has intestine moistening antidiarrheal, hemostasis, anthelmintic effect.Dysentery bacterium, Bacillus typhi, escherichia coli, tubercule bacillus there is inhibitory action.
Fructus Toosendan is the fruit of Meliaceae plant Fructus Toosendan.Contain Toosendanin, alkaloid, resin, tannin.Cold in nature, bitter in the mouth; Slightly poisonous.Effect has except that damp and hot, clearing away liver-fire, pain relieving, parasite killing." herbal classic " puts down in writing main warm disease, typhoid fever is too hot tired mad, kills three scabies and steals the diuresis water channel.
Radix Sanguisorbae is the root and rhizome of dicotyledon medicine rosaceous plant Radix Sanguisorbae, contains zigu-glucoside I, II, sangushsorbin A, B, E and gallic acid, tannin etc.Cold nature, bitter in the mouth, acid, puckery.Skin ulcer, heat-clearing and toxic substances removing, astringing to arrest diarrhea are held back in detoxifcation.
The present invention is a kind of Chinese medicine formula of special control eliminating fish parasites disease, contain medicinal herb componentses such as Pericarpium Granati, Radix Sophorae Flavescentis, Fructus Toosendan, Ramulus Cinnamomi, Herba Artemisiae Annuae, Radix Sanguisorbae, Radix Scutellariae, decoction liquor is used for the dipping or the full pool spilling head of fish body, and each component is reasonably combined, has following advantage:
1. raw material is according to the formulation principle of Chinese herbal medicine, and is to the not damage of fish body, quite remarkable to the parasitic killing effect of fish body when strengthening drug effect, for the eliminating fish parasites disease good diseases prevention is arranged, the effect of curing the disease;
2. degradable under field conditions (factors) has no side effect, and can not influence the orthobiosis of Fish, can not produce residually in the fish body, can not influence the local flavor of the flesh of fish.
3. non-corrosiveness is safe in utilization, and it is pollution-free to water environment to splash;
4. reasonably use influences such as breeding environments (dissolved oxygen, pH value) less;
5. its raw material source is stable, and cheap, production technology is simple.
Fig. 1 is the contrast sketch map that the embodiment of the invention 1,2,3,4 and 0.01 ‰ copper-bath influence fishpond algae class.
Fig. 2 is the contrast sketch map that the embodiment of the invention 1,2,3,4 and 0.01 ‰ copper-bath influence the fishpond water-soluble oxygen.
Fig. 3 is the embodiment of the invention 1,2,3,4 safe concentration experimental result sketch maps.
The specific embodiment:
Embodiment 1:
Get Pericarpium Granati 15～25 grams, Radix Sophorae Flavescentis 15～25 grams, Fructus Toosendan 12～18 grams, Ramulus Cinnamomi 8～12 grams, Herba Artemisiae Annuae 8～12 grams, Radix Sanguisorbae 8～12 grams, Radix Scutellariae 12～18 grams, every flavor medicine can be chosen in described scope, but weight should be 100 grams.
Medicine and water are immersion in 1: 20 6 hours by mass ratio, and little fiery 30 minutes after boiling, the use of can splashing after the cold of drying in the air is cultured water by cubic meter and is splashed with the 100ml medicinal liquid, splashes and wants evenly.
Embodiment 2:
Get Pericarpium Granati 25 grams, Radix Sophorae Flavescentis 15 grams, Fructus Toosendan 16 grams, Ramulus Cinnamomi 12 grams, Herba Artemisiae Annuae 8 grams, Radix Sanguisorbae 12 grams, Radix Scutellariae 12 grams, is immersion in 1: 20 6 hours with medicine and water by mass ratio, it is little fiery 30 minutes to boil the back, the use of to splash after the cold of drying in the air, culture water by cubic meter and splash, splash and want evenly with the 100ml medicinal liquid.
Embodiment 3:
Get Pericarpium Granati 15 grams, Radix Sophorae Flavescentis 25 grams, Fructus Toosendan 18 grams, Ramulus Cinnamomi 10 grams, Herba Artemisiae Annuae 12 grams, Radix Sanguisorbae 8 grams, Radix Scutellariae 12 grams, medicine and water are pressed mass ratio immersion in 1: 100 6 hours, it is little fiery 30 minutes to boil the back, behind 20 times of the cool thin ups of drying in the air, gets final product in 90 minutes in the fish immersion medicinal liquid that will fall ill.
Embodiment 4:
Get Pericarpium Granati 20 grams, Radix Sophorae Flavescentis 20 grams, Fructus Toosendan 15 grams, Ramulus Cinnamomi 10 grams, Herba Artemisiae Annuae 10 grams, Radix Sanguisorbae 10 grams, Radix Scutellariae 15 grams, medicine and water are pressed mass ratio immersion in 1: 100 6 hours, it is little fiery 30 minutes to boil the back, behind 20 times of the cool thin ups of drying in the air, gets final product in 90 minutes in the fish immersion medicinal liquid that will fall ill.
Result of use is as follows:
1. splashed back 120 minutes with the method for embodiment 1,2, insecticidal effect is as shown in table 1:
Table 1
| Experimental group | The oblique tube insect mortality rate | The Trichodina mortality rate |
| The compound Chinese herb group | 89％ | 83％ |
2. after soaking with the method for embodiment 3,4, insecticidal effect is as shown in table 2:
Table 2
| Compound Chinese herb solution soaking killing effect changes in time | |||||||||
| Time (minute) | 5 | 10 | 15 | 20 | 25 | 30 | 40 | 60 | 90 |
| Oblique tube insect mortality rate % on the | 0 | 0 | 0 | 0 | 0 | 33 | 54 | 77 | 100 |
| External oblique tube insect mortality rate % | 0 | 0 | 0 | 0 | 23 | 47 | 100 | 100 | 100 |
3. the embodiment of the invention 1,2,3,4 and 0.01 ‰ copper-bath are to the contrast of fishpond algae class influence as shown in Figure 1.
4. use the embodiment of the invention 1,2,3,4 and 0.01 ‰ copper-bath 12 hours as shown in Figure 2 to the contrast of fishpond water-soluble oxygen influence.
0.01 ‰ copper sulfate is extremely remarkable to the killing action of algae as shown in Figure 1, after 12 hours in the water of the blank fishpond of not dosing the algae gross density be 16.6 * 10
7N/L adds that the algae gross density drops to 2 * 10 in the water of copper sulfate fishpond
7N/L finally causes as shown in Figure 2, and dissolved oxygen is reduced to 4.8mg/L after 12 hours, and compound Chinese herb group dissolved oxygen then remains on about 8mg/L.
5. the safe concentration experimental result as shown in Figure 3.
The 24h LC50 of 1,2,3, the 4 pairs of Carassius auratuss of the embodiment of the invention that obtained by acute toxicity testing is 0.32%, and 48h LC50 is 0.31%, and 96hLC50 is 0.31%, and initial LC50 is 0.31%; Trying to achieve the embodiment of the invention 1,2,3,4 safe concentrations of using by empirical equation in addition is 0.898 ‰ (mass ratio).
Claims (2)
1. Chinese medicine formula of preventing and treating the eliminating fish parasites disease is characterized in that each weight percentages of components is as follows:
Pericarpium Granati 15～25%
Radix Sophorae Flavescentis 15～25%
Fructus Toosendan 12～18%
Ramulus Cinnamomi 8～12%
Herba Artemisiae Annuae 8～12%
Radix Sanguisorbae 8～12%
Radix Scutellariae 12～18%.
2. the Chinese medicine formula of control eliminating fish parasites disease according to claim 1 is characterized in that each weight percentages of components is as follows:
Pericarpium Granati 20%
Radix Sophorae Flavescentis 20%
Fructus Toosendan 15%
Ramulus Cinnamomi 15%
Herba Artemisiae Annuae 10%
Radix Sanguisorbae 10%
Radix Scutellariae 15%.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2007100111305A CN101040936B (en) | 2007-04-28 | 2007-04-28 | Compound Chinese traditional medicine agent for preventing fish verminosis |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2007100111305A CN101040936B (en) | 2007-04-28 | 2007-04-28 | Compound Chinese traditional medicine agent for preventing fish verminosis |
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| CN101040936A true CN101040936A (en) | 2007-09-26 |
| CN101040936B CN101040936B (en) | 2011-10-19 |
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| CN2007100111305A Expired - Fee Related CN101040936B (en) | 2007-04-28 | 2007-04-28 | Compound Chinese traditional medicine agent for preventing fish verminosis |
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Cited By (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102894208A (en) * | 2012-08-27 | 2013-01-30 | 广东海大集团股份有限公司 | Chinese herbal medicine feedstuff additive used for preventing carassius auratus neosporosis |
| CN104258348A (en) * | 2014-10-11 | 2015-01-07 | 杨成胜 | Mylopharyngodon piceus growth-promoting health Chinese herbal composition |
| CN104547811A (en) * | 2014-12-30 | 2015-04-29 | 杨成胜 | Chinese herbal medicine preparation for preventing parasites in fish |
| CN105012610A (en) * | 2015-08-06 | 2015-11-04 | 杨壮志 | Superfine powder traditional Chinese veterinary medicine for treating trichodiniasis of loach and preparing method |
| CN105232850A (en) * | 2015-11-11 | 2016-01-13 | 郑州后羿制药有限公司 | Chinese herbal medicine fermentative extracting solution for preventing and controlling parasitic diseases of freshwater fish and preparation method thereof |
| CN105327173A (en) * | 2015-11-19 | 2016-02-17 | 集美大学 | Chinese herbal medicine compound additive for preventing and treating fish parasite diseases and production method of Chinese herbal medicine compound additive |
| CN106386892A (en) * | 2016-08-16 | 2017-02-15 | 广西大学 | A natural vegetable insecticide and a preparing method thereof |
| CN109588585A (en) * | 2019-01-29 | 2019-04-09 | 华电云南发电有限公司 | It is a kind of to prevent and treat the soft naked feed for fingerling for splitting buttocks fish parasite disease of thorn |
| CN112334007A (en) * | 2018-06-13 | 2021-02-05 | 发酵专家公司 | Antiparasitic compositions |
| NO345471B1 (en) * | 2018-01-29 | 2021-02-22 | Jeonjin Bio Co Ltd | Pharmaceutical compositions for preventing or treating a sea lice disease comprising an extract of Sophora flavescens Aiton or fractions thereof. |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP3692946B2 (en) * | 2001-02-14 | 2005-09-07 | 日本電気株式会社 | Information arrival notification system and information arrival notification method used therefor |
| CN1162446C (en) * | 2001-05-10 | 2004-08-18 | 上海华谊生物技术有限公司 | Insulinotropic hormone secretion peptide derivative |
-
2007
- 2007-04-28 CN CN2007100111305A patent/CN101040936B/en not_active Expired - Fee Related
Cited By (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102894208A (en) * | 2012-08-27 | 2013-01-30 | 广东海大集团股份有限公司 | Chinese herbal medicine feedstuff additive used for preventing carassius auratus neosporosis |
| CN104258348A (en) * | 2014-10-11 | 2015-01-07 | 杨成胜 | Mylopharyngodon piceus growth-promoting health Chinese herbal composition |
| CN104547811A (en) * | 2014-12-30 | 2015-04-29 | 杨成胜 | Chinese herbal medicine preparation for preventing parasites in fish |
| CN105012610A (en) * | 2015-08-06 | 2015-11-04 | 杨壮志 | Superfine powder traditional Chinese veterinary medicine for treating trichodiniasis of loach and preparing method |
| CN105232850A (en) * | 2015-11-11 | 2016-01-13 | 郑州后羿制药有限公司 | Chinese herbal medicine fermentative extracting solution for preventing and controlling parasitic diseases of freshwater fish and preparation method thereof |
| CN105327173A (en) * | 2015-11-19 | 2016-02-17 | 集美大学 | Chinese herbal medicine compound additive for preventing and treating fish parasite diseases and production method of Chinese herbal medicine compound additive |
| CN105327173B (en) * | 2015-11-19 | 2019-04-30 | 集美大学 | A kind of Chinese herb compound additive and its production method for preventing and treating eliminating fish parasites disease |
| CN106386892A (en) * | 2016-08-16 | 2017-02-15 | 广西大学 | A natural vegetable insecticide and a preparing method thereof |
| NO345471B1 (en) * | 2018-01-29 | 2021-02-22 | Jeonjin Bio Co Ltd | Pharmaceutical compositions for preventing or treating a sea lice disease comprising an extract of Sophora flavescens Aiton or fractions thereof. |
| CN112334007A (en) * | 2018-06-13 | 2021-02-05 | 发酵专家公司 | Antiparasitic compositions |
| CN109588585A (en) * | 2019-01-29 | 2019-04-09 | 华电云南发电有限公司 | It is a kind of to prevent and treat the soft naked feed for fingerling for splitting buttocks fish parasite disease of thorn |
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|---|---|
| CN101040936B (en) | 2011-10-19 |
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