CN101036732A - Chinese medicine preparation for esophagus cancer and its compounding process - Google Patents
Chinese medicine preparation for esophagus cancer and its compounding process Download PDFInfo
- Publication number
- CN101036732A CN101036732A CNA2006100444046A CN200610044404A CN101036732A CN 101036732 A CN101036732 A CN 101036732A CN A2006100444046 A CNA2006100444046 A CN A2006100444046A CN 200610044404 A CN200610044404 A CN 200610044404A CN 101036732 A CN101036732 A CN 101036732A
- Authority
- CN
- China
- Prior art keywords
- parts
- qukedan
- pill
- chinese medicine
- oleum sesami
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000003814 drug Substances 0.000 title claims description 33
- 238000000034 method Methods 0.000 title claims description 9
- 238000002360 preparation method Methods 0.000 title description 10
- 208000000461 Esophageal Neoplasms Diseases 0.000 title description 2
- 238000013329 compounding Methods 0.000 title description 2
- 201000004101 esophageal cancer Diseases 0.000 title description 2
- 239000006187 pill Substances 0.000 claims abstract description 21
- NLXLAEXVIDQMFP-UHFFFAOYSA-N Ammonia chloride Chemical compound [NH4+].[Cl-] NLXLAEXVIDQMFP-UHFFFAOYSA-N 0.000 claims abstract description 14
- 239000011021 lapis lazuli Substances 0.000 claims abstract description 13
- 235000010339 sodium tetraborate Nutrition 0.000 claims abstract description 13
- DTGKSKDOIYIVQL-WEDXCCLWSA-N (+)-borneol Chemical compound C1C[C@@]2(C)[C@@H](O)C[C@@H]1C2(C)C DTGKSKDOIYIVQL-WEDXCCLWSA-N 0.000 claims abstract description 9
- 229910021538 borax Inorganic materials 0.000 claims abstract description 9
- 239000004328 sodium tetraborate Substances 0.000 claims abstract description 9
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims abstract description 5
- 208000017897 Carcinoma of esophagus Diseases 0.000 claims description 20
- 206010030155 Oesophageal carcinoma Diseases 0.000 claims description 14
- 201000005619 esophageal carcinoma Diseases 0.000 claims description 14
- 241000283956 Manis Species 0.000 claims description 12
- 239000007788 liquid Substances 0.000 claims description 12
- 239000002994 raw material Substances 0.000 claims description 9
- 229940079593 drug Drugs 0.000 claims description 6
- 239000008188 pellet Substances 0.000 claims description 5
- 239000000843 powder Substances 0.000 claims description 5
- 239000003610 charcoal Substances 0.000 claims description 4
- 150000001875 compounds Chemical class 0.000 claims description 4
- 239000006071 cream Substances 0.000 claims description 4
- 239000013078 crystal Substances 0.000 claims description 4
- 239000000796 flavoring agent Substances 0.000 claims description 4
- 235000019634 flavors Nutrition 0.000 claims description 4
- 239000002184 metal Substances 0.000 claims description 3
- 238000003756 stirring Methods 0.000 claims description 3
- 235000021419 vinegar Nutrition 0.000 claims description 3
- 239000000052 vinegar Substances 0.000 claims description 3
- 239000000463 material Substances 0.000 claims description 2
- 239000011505 plaster Substances 0.000 claims description 2
- 241000972155 Moschus Species 0.000 claims 5
- 239000003795 chemical substances by application Substances 0.000 claims 1
- 239000000203 mixture Substances 0.000 claims 1
- 206010028980 Neoplasm Diseases 0.000 abstract description 25
- 230000000694 effects Effects 0.000 abstract description 19
- 208000002193 Pain Diseases 0.000 abstract description 15
- 201000011510 cancer Diseases 0.000 abstract description 6
- 239000006260 foam Substances 0.000 abstract description 4
- 239000012528 membrane Substances 0.000 abstract description 4
- 235000003642 hunger Nutrition 0.000 abstract description 2
- REPVLJRCJUVQFA-UHFFFAOYSA-N (-)-isopinocampheol Natural products C1C(O)C(C)C2C(C)(C)C1C2 REPVLJRCJUVQFA-UHFFFAOYSA-N 0.000 abstract 1
- JGDCRWYOMWSTFC-AZGSIFHYSA-N 5-[(3s,5r,8r,9s,10s,11s,13r,14s,17r)-3,11,14-trihydroxy-10,13-dimethyl-12-oxo-2,3,4,5,6,7,8,9,11,15,16,17-dodecahydro-1h-cyclopenta[a]phenanthren-17-yl]pyran-2-one Chemical compound C=1([C@@H]2[C@@]3([C@@](CC2)(O)[C@H]2[C@@H]([C@@]4(C)CC[C@H](O)C[C@H]4CC2)[C@H](O)C3=O)C)C=CC(=O)OC=1 JGDCRWYOMWSTFC-AZGSIFHYSA-N 0.000 abstract 1
- -1 Agilawood Chemical compound 0.000 abstract 1
- JGDCRWYOMWSTFC-UHFFFAOYSA-N Arenobufagin Natural products C1CC(C2C(C3(C)CCC(O)CC3CC2)C(O)C2=O)(O)C2(C)C1C=1C=CC(=O)OC=1 JGDCRWYOMWSTFC-UHFFFAOYSA-N 0.000 abstract 1
- 206010004542 Bezoar Diseases 0.000 abstract 1
- 239000003390 Chinese drug Substances 0.000 abstract 1
- 241000644519 Chloritis Species 0.000 abstract 1
- 241001507943 Cormus Species 0.000 abstract 1
- 241000402754 Erythranthe moschata Species 0.000 abstract 1
- 241000283966 Pholidota <mammal> Species 0.000 abstract 1
- 235000019270 ammonium chloride Nutrition 0.000 abstract 1
- 229940116229 borneol Drugs 0.000 abstract 1
- CKDOCTFBFTVPSN-UHFFFAOYSA-N borneol Natural products C1CC2(C)C(C)CC1C2(C)C CKDOCTFBFTVPSN-UHFFFAOYSA-N 0.000 abstract 1
- 238000001816 cooling Methods 0.000 abstract 1
- 229910000366 copper(II) sulfate Inorganic materials 0.000 abstract 1
- JZCCFEFSEZPSOG-UHFFFAOYSA-L copper(II) sulfate pentahydrate Chemical compound O.O.O.O.O.[Cu+2].[O-]S([O-])(=O)=O JZCCFEFSEZPSOG-UHFFFAOYSA-L 0.000 abstract 1
- DTGKSKDOIYIVQL-UHFFFAOYSA-N dl-isoborneol Natural products C1CC2(C)C(O)CC1C2(C)C DTGKSKDOIYIVQL-UHFFFAOYSA-N 0.000 abstract 1
- 235000020888 liquid diet Nutrition 0.000 abstract 1
- 239000008159 sesame oil Substances 0.000 abstract 1
- 235000011803 sesame oil Nutrition 0.000 abstract 1
- 230000037351 starvation Effects 0.000 abstract 1
- 230000035922 thirst Effects 0.000 abstract 1
- 235000013305 food Nutrition 0.000 description 16
- 210000003238 esophagus Anatomy 0.000 description 12
- 238000002512 chemotherapy Methods 0.000 description 10
- 230000028327 secretion Effects 0.000 description 9
- 230000008961 swelling Effects 0.000 description 9
- 208000019505 Deglutition disease Diseases 0.000 description 8
- 201000009030 Carcinoma Diseases 0.000 description 7
- 244000153234 Hibiscus abelmoschus Species 0.000 description 7
- 239000008280 blood Substances 0.000 description 6
- 210000004369 blood Anatomy 0.000 description 6
- 235000012149 noodles Nutrition 0.000 description 6
- 230000001575 pathological effect Effects 0.000 description 6
- 230000001737 promoting effect Effects 0.000 description 6
- 230000036461 convulsion Effects 0.000 description 5
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 5
- 206010010904 Convulsion Diseases 0.000 description 4
- 230000001154 acute effect Effects 0.000 description 4
- 238000003745 diagnosis Methods 0.000 description 4
- 201000010099 disease Diseases 0.000 description 4
- 210000003026 hypopharynx Anatomy 0.000 description 4
- 239000008267 milk Substances 0.000 description 4
- 235000013336 milk Nutrition 0.000 description 4
- 210000004080 milk Anatomy 0.000 description 4
- 208000025402 neoplasm of esophagus Diseases 0.000 description 4
- 231100000614 poison Toxicity 0.000 description 4
- 206010007247 Carbuncle Diseases 0.000 description 3
- 206010008190 Cerebrovascular accident Diseases 0.000 description 3
- 206010036790 Productive cough Diseases 0.000 description 3
- 208000006011 Stroke Diseases 0.000 description 3
- 206010047700 Vomiting Diseases 0.000 description 3
- 210000001015 abdomen Anatomy 0.000 description 3
- 208000002399 aphthous stomatitis Diseases 0.000 description 3
- 230000008901 benefit Effects 0.000 description 3
- 230000003203 everyday effect Effects 0.000 description 3
- 239000012530 fluid Substances 0.000 description 3
- 208000024891 symptom Diseases 0.000 description 3
- 239000003440 toxic substance Substances 0.000 description 3
- 230000008673 vomiting Effects 0.000 description 3
- 206010063409 Acarodermatitis Diseases 0.000 description 2
- 206010020741 Hyperpyrexia Diseases 0.000 description 2
- 206010062717 Increased upper airway secretion Diseases 0.000 description 2
- 201000007100 Pharyngitis Diseases 0.000 description 2
- 241000447727 Scabies Species 0.000 description 2
- 208000005392 Spasm Diseases 0.000 description 2
- 210000000988 bone and bone Anatomy 0.000 description 2
- 230000008859 change Effects 0.000 description 2
- 229940126678 chinese medicines Drugs 0.000 description 2
- 230000004087 circulation Effects 0.000 description 2
- 239000003172 expectorant agent Substances 0.000 description 2
- 230000003419 expectorant effect Effects 0.000 description 2
- 230000036449 good health Effects 0.000 description 2
- 208000014617 hemorrhoid Diseases 0.000 description 2
- 230000006872 improvement Effects 0.000 description 2
- 235000021056 liquid food Nutrition 0.000 description 2
- 238000004519 manufacturing process Methods 0.000 description 2
- 231100000957 no side effect Toxicity 0.000 description 2
- 208000026435 phlegm Diseases 0.000 description 2
- 238000001959 radiotherapy Methods 0.000 description 2
- 208000005687 scabies Diseases 0.000 description 2
- 230000004936 stimulating effect Effects 0.000 description 2
- 239000000126 substance Substances 0.000 description 2
- 230000004083 survival effect Effects 0.000 description 2
- 230000001225 therapeutic effect Effects 0.000 description 2
- 231100000331 toxic Toxicity 0.000 description 2
- 230000002588 toxic effect Effects 0.000 description 2
- 206010000087 Abdominal pain upper Diseases 0.000 description 1
- 201000004384 Alopecia Diseases 0.000 description 1
- 201000000736 Amenorrhea Diseases 0.000 description 1
- 206010001928 Amenorrhoea Diseases 0.000 description 1
- 206010006895 Cachexia Diseases 0.000 description 1
- 206010007882 Cellulitis Diseases 0.000 description 1
- 206010008479 Chest Pain Diseases 0.000 description 1
- 206010008631 Cholera Diseases 0.000 description 1
- 206010010071 Coma Diseases 0.000 description 1
- 208000035473 Communicable disease Diseases 0.000 description 1
- 206010010144 Completed suicide Diseases 0.000 description 1
- 206010012373 Depressed level of consciousness Diseases 0.000 description 1
- 206010012735 Diarrhoea Diseases 0.000 description 1
- 206010013887 Dysarthria Diseases 0.000 description 1
- 206010013954 Dysphoria Diseases 0.000 description 1
- 208000007882 Gastritis Diseases 0.000 description 1
- 241000167880 Hirundinidae Species 0.000 description 1
- 206010061218 Inflammation Diseases 0.000 description 1
- 206010026749 Mania Diseases 0.000 description 1
- 208000019255 Menstrual disease Diseases 0.000 description 1
- 208000007101 Muscle Cramp Diseases 0.000 description 1
- 206010062575 Muscle contracture Diseases 0.000 description 1
- 206010068319 Oropharyngeal pain Diseases 0.000 description 1
- 244000046052 Phaseolus vulgaris Species 0.000 description 1
- 235000010627 Phaseolus vulgaris Nutrition 0.000 description 1
- 241000233805 Phoenix Species 0.000 description 1
- 208000003251 Pruritus Diseases 0.000 description 1
- 208000001431 Psychomotor Agitation Diseases 0.000 description 1
- 206010038743 Restlessness Diseases 0.000 description 1
- 206010040943 Skin Ulcer Diseases 0.000 description 1
- 208000005718 Stomach Neoplasms Diseases 0.000 description 1
- 208000033809 Suppuration Diseases 0.000 description 1
- 206010042674 Swelling Diseases 0.000 description 1
- 206010045171 Tumour pain Diseases 0.000 description 1
- 208000025865 Ulcer Diseases 0.000 description 1
- 208000027418 Wounds and injury Diseases 0.000 description 1
- 238000009825 accumulation Methods 0.000 description 1
- 208000016150 acute pharyngitis Diseases 0.000 description 1
- 230000002411 adverse Effects 0.000 description 1
- 231100000360 alopecia Toxicity 0.000 description 1
- 231100000540 amenorrhea Toxicity 0.000 description 1
- 230000000202 analgesic effect Effects 0.000 description 1
- 208000007502 anemia Diseases 0.000 description 1
- 210000001557 animal structure Anatomy 0.000 description 1
- 208000006673 asthma Diseases 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 238000001574 biopsy Methods 0.000 description 1
- 230000017531 blood circulation Effects 0.000 description 1
- 230000000973 chemotherapeutic effect Effects 0.000 description 1
- 230000001684 chronic effect Effects 0.000 description 1
- 208000023652 chronic gastritis Diseases 0.000 description 1
- 208000006111 contracture Diseases 0.000 description 1
- 230000001934 delay Effects 0.000 description 1
- 238000007599 discharging Methods 0.000 description 1
- 208000002173 dizziness Diseases 0.000 description 1
- 239000002895 emetic Substances 0.000 description 1
- 238000001839 endoscopy Methods 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 208000028299 esophageal disease Diseases 0.000 description 1
- 239000000284 extract Substances 0.000 description 1
- 206010017758 gastric cancer Diseases 0.000 description 1
- 238000005469 granulation Methods 0.000 description 1
- 230000003179 granulation Effects 0.000 description 1
- 210000003128 head Anatomy 0.000 description 1
- 230000036541 health Effects 0.000 description 1
- 235000008216 herbs Nutrition 0.000 description 1
- 208000021760 high fever Diseases 0.000 description 1
- 208000015181 infectious disease Diseases 0.000 description 1
- 230000004054 inflammatory process Effects 0.000 description 1
- 208000014674 injury Diseases 0.000 description 1
- 210000000936 intestine Anatomy 0.000 description 1
- 230000007803 itching Effects 0.000 description 1
- 210000004185 liver Anatomy 0.000 description 1
- 210000004072 lung Anatomy 0.000 description 1
- 235000012054 meals Nutrition 0.000 description 1
- 235000013372 meat Nutrition 0.000 description 1
- 230000002175 menstrual effect Effects 0.000 description 1
- 210000003097 mucus Anatomy 0.000 description 1
- 210000003205 muscle Anatomy 0.000 description 1
- 230000001338 necrotic effect Effects 0.000 description 1
- 235000021590 normal diet Nutrition 0.000 description 1
- 230000007170 pathology Effects 0.000 description 1
- 239000002304 perfume Substances 0.000 description 1
- 230000007096 poisonous effect Effects 0.000 description 1
- 230000001047 pyretic effect Effects 0.000 description 1
- 230000005855 radiation Effects 0.000 description 1
- 238000011084 recovery Methods 0.000 description 1
- 230000002040 relaxant effect Effects 0.000 description 1
- 206010039083 rhinitis Diseases 0.000 description 1
- 201000000849 skin cancer Diseases 0.000 description 1
- 201000008261 skin carcinoma Diseases 0.000 description 1
- 206010040872 skin infection Diseases 0.000 description 1
- 231100000019 skin ulcer Toxicity 0.000 description 1
- 239000002893 slag Substances 0.000 description 1
- 208000026473 slurred speech Diseases 0.000 description 1
- 210000000813 small intestine Anatomy 0.000 description 1
- 210000004872 soft tissue Anatomy 0.000 description 1
- 235000013599 spices Nutrition 0.000 description 1
- 210000003802 sputum Anatomy 0.000 description 1
- 208000024794 sputum Diseases 0.000 description 1
- 201000011549 stomach cancer Diseases 0.000 description 1
- 208000003265 stomatitis Diseases 0.000 description 1
- 238000001356 surgical procedure Methods 0.000 description 1
- 206010042772 syncope Diseases 0.000 description 1
- 238000002560 therapeutic procedure Methods 0.000 description 1
- 238000000015 thermotherapy Methods 0.000 description 1
- 210000001519 tissue Anatomy 0.000 description 1
- 206010044008 tonsillitis Diseases 0.000 description 1
- 208000004371 toothache Diseases 0.000 description 1
- 231100000419 toxicity Toxicity 0.000 description 1
- 230000001988 toxicity Effects 0.000 description 1
- 231100000820 toxicity test Toxicity 0.000 description 1
- 230000008359 toxicosis Effects 0.000 description 1
- 239000003053 toxin Substances 0.000 description 1
- 231100000765 toxin Toxicity 0.000 description 1
- 230000001131 transforming effect Effects 0.000 description 1
- 230000008736 traumatic injury Effects 0.000 description 1
- 231100000397 ulcer Toxicity 0.000 description 1
- 239000002435 venom Substances 0.000 description 1
- 210000001048 venom Anatomy 0.000 description 1
- 231100000611 venom Toxicity 0.000 description 1
- 238000010792 warming Methods 0.000 description 1
Landscapes
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicines Containing Plant Substances (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
The invention discloses a traditional Chinese drug named as 'qukedan' therapying the oesophagus cancer, formed mainly from Lapis Chloriti, Borax, Salmiac, Cormu satgae, Borneol, Blue vitriol, Agilawood, Arenobufagin, Pangolin, Bezoar, Musk and Sesame oil at a certain proportion by weight. The 'qukedan' has effects such as blood-cooling, detumescence, dissipating hard mass, dissolving membrane, rupturing membrane, getting through the tumour of gullet. The usage of the 'qukedan'is that: when the patients suffering from gullet tumour and carcer can not eat anything even water, the serious ones keep one pill in mouth for half an hour until the stickies in a mixed color of red, white and yellow with mucosity and sticky foam are spitted, therefore the tumour is dissolved and broken. When the paitients can eat liquid diet, the time for keeping one pill in mouth is changed to be three hours. After continual keeping one pill in mouth for three days, the paitient stops taking the 'qukedan'. The 'qukedan' is a hereditary skill handed down from five ancestors, making contributions for therapying the oesophagus cancer. The 'qukedan' can make the tumor membrane break and drop out. therefore the lumen is broadened and unobstructed. The 'qukedan' can also avoid the patients dying from thirst and starvation and reduce patients pain of operation and the expensive operation cost.
Description
[technical field]
The present invention relates to Chinese medicine of a kind of special treatment of esophagus cancer and preparation method thereof, belong to the field of Chinese medicines.
[background technology]
Esophageal tumor, be commonly called as and be the food disease of choking, the just current esophageal carcinoma of saying, according to the practical experience of number of the present invention for the treatment esophageal carcinoma, the tumor of being suffered from the esophagus is directly blocked the esophagus tube chamber, drink water and do not swallow water, have a meal and do not swallow food, bring in various degree misery and life danger to the patient in a word, treatment esophagus carcinoma all is to adopt chemotherapy and operation basically on the modern medicine, though chemotherapy energy kill cancer cell also can kill the normal cell of human body simultaneously.Patient more than percent 90% can make alopecia, anemia, health skeletonize often because of chemotherapy, because of cachexia dead.Method of another treatment esophageal carcinoma is operation, and operation will be paid expensive Operation Fee, and in, end-stage patients' relapse rate height, bring many financial burden and many-sided loss for patient family.Patent No. 92109258.X " a kind of oral liquid for curing cancer and manufacture method thereof " is formulated by 25 flavor raw material of Chinese medicine; The patent No. 93103912.6 " oral liquid for treatment of esophagus disease and manufacture method thereof " is to be made by 11 flavor Chinese medicines, and a Chinese medicine Sal Ammoniacus is wherein all arranged, and all is oral medicine, and effect is unsatisfactory.
[summary of the invention]
Purpose of the present invention just provides a kind of Chinese medicine of pure natural, makes raw material by big right Ore and animal organ pipe, and the cost of making by the science compatibility is low, and curative effect is high sucks pill and compound method thereof:
Medicament selection Lapis Micae Aureus of the present invention, Borax, Sal Ammoniacus, Cornu Saigae Tataricae, Borneolum Syntheticum, Chalcanthitum, Lignum Aquilariae Resinatum, Venenum Bufonis, Squama Manis, Calculus Bovis, Moschus, Oleum Sesami make up, and make each efficacy of drugs produce synergism, thereby can effectively treat esophageal carcinoma; Wherein, selecting Lapis Micae Aureus for use, is because of it has the circulation of qi promoting expectorant, the checking hyperfunction of the liver for relieving convulsion effect; Control chronic bronchial patient's dense thick, the diseases such as expectoration is difficult, fullness in the chest out of breath, dysphoria of abundant expectoration, also control the infantile convulsion of children's acute hyperpyrexia and twitch; Select Borax, it has detoxicating, relieving inflammation, removing heat-phlegm effect; Laryngopharynx swelling and pain, ophthalmic secretions increase due to treatment acute pharyngolaryngitis, tonsillitis, the stomatitis; Select Sal Ammoniacus, it has clear swollen, the dispelling wind-evil and transforming calculus effect of detoxifcation, controls malignant tumor such as carbuncle, skin infection, thermotherapy toxic swelling, laryngopharynx swelling and pain and esophagus carcinoma, gastric cancer, rhinitis cancer, controls various scabies; Select Cornu Saigae Tataricae for use, cure mainly due to wound that face due to cold is warmed, swelling pain of head, have a dizzy spell, susceptible to lose temper due to restlessness and various acute infectious disease, high fever, obnubilation, speech is manic; Frightened pain is twitched and relaxing tumor pain; Select Borneolum Syntheticum for use, it have out steal, refreshment detoxifcation analgesic effect, cure mainly acute hyperpyrexia, apoplexy is fallen in a swoon, insane onste, limbs tic, aphtha of the mouth and tongue, the pain of festering, acute pharyngitis, laryngopharynx swelling and pain are to treatment carbuncle, the red and swollen hemorrhoid of pyretic toxicity are leaked blood that special efficacy is arranged; Select Chalcanthitum for use, its external detoxifcation removing the necrotic tissue, because of obeying emetic toxin expelling.Aphtha, toothache are controlled in external, and laryngopharynx swelling and pain, phoenix eyes are red mashed, and hemorrhoid heat is swollen, carbuncle is malicious broken, for oral administration control apoplexy from the beginning of, chat sputum highest of pain outbreak, all diseases and eat poisonous substance, alimentary toxicosis etc. by mistake; Select Lignum Aquilariae Resinatum for use, it has promoting the circulation of QI to relieve pain, warming middle-JIAO to arrest vomiting, lowering the adverse QI to relieve asthma effect, and control the spasm that causes of illness such as menoxenia, qi depression to blood stasis, lower abdomen pain and chronic gastritis and have a stomachache, mouthful vomiting watery fluid, the cold fearness of abdomen is cold, and extremity are not warm; Select Venenum Bufonis for use, its sensible removing toxic substances and promoting subsidence of swelling is controlled cholera vomiting and diarrhoea, sore throat, trusted subordinate's angor, venom, scabies, the skin carcinoma disease of itching; Select Squama Manis for use, it has promoting blood circulation to remove blood stasis, and women's amenorrhea due to stagnation of blood, not smooth through going out is controlled in the stimulating milk secretion of stimulating the menstrual flow, reducing swelling and alleviating pain effect.Enclosed mass, limbs contracture, flesh rigidity of soft tissues pain in the abdomen are controlled swollen ulcer drug from the beginning of not suppurating as yet or difficulty in discharging of pus; Select Calculus Bovis for use, its heat-clearing and toxic substances removing, open expectorant, calm the frightened, open and steal, control calentura coma, slurred speech, insane sick convulsion with spasms, throat aphtha of the mouth and tongue, removing toxic substances and promoting subsidence of swelling; Select Moschus for use, it can ward off dirty, have one's ideas straightened out, collateral dredging, control apoplexy syncope due to accumulation of phlegm, infantile convulsion, traumatic injury, trusted subordinate's sudden pain, external treatment cellulitis, skin ulcer are swollen; Select Oleum Sesami for use, its Bears physical strength profiting, longue meat, strong bone cephalocathartic, hard muscles and bones, clothes are made light of one's life by commiting suicide not oldly for a long time, prolong life, and the tonifying five ZANG-organs lung qi, to end the heart frightened, sharp intestine and small intestine, old Oleum sesami soft extracts clothes, but granulation promoting is put on flesh, pain relieving, all flavor medicines can be bonded into ball again.
The consumption of drug component of the present invention also is to carry out several generations through the inventor to grope, improve, sum up each amounts of components of drawing in a large number for all to have better curative effect in the following weight parts scope, is listed as follows:
The better scope optimum range of title effective range
Lapis Micae Aureus 40-70 part 45-65 50-60
Borax 60-85 part 65-80 65-75
Sal Ammoniacus 60-85 part 65-80 70-80
Cornu Saigae Tataricae 25-50 part 30-45 35-45
Borneolum Syntheticum 65-85 part 70-85 70-80
Chalcanthitum 50-75 part 55-70 55-65
Lignum Aquilariae Resinatum 70-90 part 75-90 75-85
Venenum Bufonis 55-75 part 60-75 60-70
Squama Manis 65-85 part 65-80 70-80
Calculus Bovis 50-70 part 50-65 55-65
Moschus 35-55 part 40-55 45-50
Oleum Sesami 150-220 part 180-210 180-200
The compound method of treatment esophageal carcinoma Chinese medicine preparation is as follows:
(1) at first the raw material of choosing is weighed up, makes by weight part, at first Sal Ammoniacus is ground into the powder face and puts into marmite, (noting: keep away metal) adds water logging and do not have medicated powder, boils about 20 minutes, crosses and filters to remove slag, continues to employ clean Sal Ammoniacus liquid;
(2) cleaner Sal Ammoniacus liquid is poured in the marmite, added the vinegar of 0.5 times of amount in the marmite, with burning marmite, the limit stirs evenly then, and fire decocts to the charcoal yellow crystals and is degree;
(3) be stirred into sticky shape cream liquid with adding the Oleum Sesami that weighs up in the charcoal yellow crystals, at this moment temperature is approximately the 60-80 degree; Again with the Lapis Micae Aureus that weighs up, Borax, Cornu Saigae Tataricae, Borneolum Syntheticum, Chalcanthitum, Lignum Aquilariae Resinatum is looked forward or upwards shortcake, Squama Manis, Calculus Bovis, pour into after the Moschus powder face mixes stir in the sticky cream liquid after, at this moment ceasing fire cools;
(4) dispelling of becoming of the compatibility that cools choke red raw material promptly (Chinese medicine plaster) become ball promptly to become to dissolve the present invention who dispels esophageal tumor, esophagus carcinoma with hands group and treat the Chinese medicine preparation of esophageal carcinoma (the red pill of choking of promptly dispelling).
Advantage of the present invention just is to have removing heat from blood, detumescence, broken hard eliminating stagnation, molten film, rupture of membranes by the property of medicine of above-mentioned each raw material, effect as can be known clearly; The tumor of getting through in the esophagus, the effect of carcinoma are arranged; In on probation for many years, heavy patient's containing half an hour ball pellet of choking of dispelling, the lighter's containing every day 24 balls pellet of choking of dispelling, containing had the white secondary colour thing of sticking foam and toughness reddish yellow to spue after 2-4 days; At this moment the carcinoma in the esophagus has dissolved and has broken apart.Change 3 hours containing balls after taking food into, serveing on three days can take effect, and can take food, and delays life; In five generations of the inventor,, treasure side handed down from one's ancestors was that side common people treat the esophagus carcinoma, and very high reputation is arranged; The containing pellet (being Chinese medicine preparation of the present invention) of choking of dispelling can make tumor body film in the esophagus come off and break, and makes tube chamber broadening, unobstructed, therefore can not make this troubles esophagus tumor patient thirsty dead, die of hunger; Prolong patient's life, more reduce the misery and the expensive surgery cost of having an operation.
[specific embodiment]
Below further set forth the beneficial effect of medicine of the present invention by concrete proportioning raw materials and clinical trial.
The Chinese medicine preparation of treatment esophageal carcinoma is the medicine pill of being manufactured by weight by following material combination:
Embodiment 1: 65 parts of Lapis Micae Aureuss, 75 parts of Boraxs, 80 parts of Sal Ammoniacuss, 45 parts of Cornu Saigae Tataricae, 80 parts of Borneolum Syntheticums, 65 parts in Chalcanthitum, 80 parts of Lignum Aquilariae Resinatum, 70 parts of Venenum Bufoniss, 75 parts of Squama Maniss, 65 parts of Calculus Boviss, 50 parts in Moschus, 210 parts in Oleum Sesami.
Embodiment 2: 60 parts of Lapis Micae Aureuss, 70 parts of Boraxs, 75 parts of Sal Ammoniacuss, 40 parts of Cornu Saigae Tataricae, 75 parts of Borneolum Syntheticums, 60 parts in Chalcanthitum, 75 parts of Lignum Aquilariae Resinatum, 65 parts of Venenum Bufoniss, 70 parts of Squama Maniss, 60 parts of Calculus Boviss, 45 parts in Moschus, 200 parts in Oleum Sesami.
Embodiment 3: 55 parts of Lapis Micae Aureuss, 65 parts of Boraxs, 70 parts of Sal Ammoniacuss, 35 parts of Cornu Saigae Tataricae, 70 parts of Borneolum Syntheticums, 55 parts in Chalcanthitum, 70 parts of Lignum Aquilariae Resinatum, 60 parts of Venenum Bufoniss, 65 parts of Squama Maniss, 55 parts of Calculus Boviss, 40 parts in Moschus, 190 parts in Oleum Sesami.
The present invention is applicant room Mr.'s long river secret prescription handed down in the family from generation to generation, and for passing on from one to another, effect is fine, spreads one's fame in order to benefit mankind through number, benefit the people, be used for society, the doctor that asks experts in recent years, joint research, array data, the clinical trial of the standard of contrasting, statistical result are gratifying.
Esophagus carninomatosis of the present invention clinical trial is as follows:
Esophageal carcinoma is one of common carcinoma of China, especially Lin County, Henan, area, Tai'an, Shandong are occurred frequently, the general excision that adopts, but end-stage patients and old person and do not have the money operator and adopt expectant treatment more, the radiation and chemotherapy side effect is big, expense is high, this group case adopts pure treatment by Chinese herbs 60 examples, and is evident in efficacy, economical and practical, have no side effect, and now reports as follows:
Case is selected: this group case 60 examples, male 45 examples, women 15 examples, age 42～73,56 years old mean age; Medical history January～1 year.Symptom is accompanied retrosternal pain, is become thin for carrying out property dysphagia, and part patient is through radiotherapy or chemotherapeutic treatment poor effect person.The treatment of employing this method.All cases are all made a definite diagnosis through CT, fibergastroscope and pathology biopsy, tumor body 0.5-4.2cm.
Therapeutic Method: 1 ball contained 1 in 30 minutes, and light disease contains 24 balls every day, promptly spues after the containing, and avoided and swallowed, and changed 3 hours after the energy influent stream food and contained 1 ball, had sticking foam and red white yellow thick secretions to spue after 2～4 days, illustrated that carcinoma is dissolved, and tube chamber is got through.Capable again CT, scope or pathologic finding after January.
Criterion of therapeutical effect: recovery from illness: the dysphagia transference cure common food of taking food, CT or scope, pathologic finding are normal.Take a turn for the better: swallow symptom and take a turn for the better, liquid food or the semi-fluid food of taking food, scope and CT examination tumor body disappear and reach 50%.Invalid: subjective symptoms takes a turn for the better, and feed is difficulty still, and CT and endoscopy do not have obvious improvement.
Therapeutic outcome: 20 examples of fully recovering account for 33%.Take a turn for the better: 23 examples account for 35%.Total effective rate is 68%.Invalid is 17 examples, accounts for 20.8%.
Brief summary: this pill is a pure Chinese medicinal preparation, is applicable to the lump type esophageal carcinoma patient that carrying out property dysphagia is made a definite diagnosis through CT, scope, in, hypomere patient effect is particularly evident.This medication is imitated significantly, and 60 routine patients cure 20 examples, 23 examples that take a turn for the better, total effective rate 68% is higher than the putting of bibliographical information, chemotherapy and operation case, and economical and practical, has no side effect, indication is wide, be applicable to put, chemotherapy is invalid or old person.
This Chinese medicine pill is multiple pure Chinese medicinal preparation, has removing heat from blood detumescence, molten film and broken hard eliminating stagnation effect, and the white thick secretions of reddish yellow generally promptly spues behind containing 24 balls, esophagus is got through, can take food liquid food or semi-fluid the food, recover normal diet after 2～4 days, do not find toxic and side effects.This group case is followed up a case by regular visits to and is recurred for the year ends 3～5 again, and the patient who has still is still living and in good health in year surplus in the of 10 so far.Next step remakes toxicity test.
Model case is as follows:
1, Gao Aimin, man, 47 years old, Daiyue District Wen Kou Zhen Wenkou one village, Tai, Shandong Province, at the beginning of 2002 3 months because of carrying out property dysphagia in the People's Hospital, Tai in esophagoscope and pathologic finding are diagnosed as the hypomere esophageal carcinoma, because of financial difficulties can not operative treatment, with containing of this pill, contained 1 ball in 30 minutes, when containing the 6th ball, the white thick liquid of reddish yellow promptly spues, containing during to 14 balls esophagus get through, the rare metal plate noodles of feed after 12 days, take food the same with the normal person after 15 days still was still living and in good health so far in 3 years.
2, Liu Guangmin, man, 52 years old, the Xi Cun of Daiyue District Liang Zhuan town, Tai, Shandong Province government's bank, November nineteen ninety-five, hypomere had the 0.3-1.2cm tumor in the esophagus because of carrying out property dysphagia is made a definite diagnosis in Tai tumour hospital row CT examination, took this pill, when the containing courageous and upright thick secretions that spues during to 6 balls, when containing to 17 balls, esophagus tumor body is dissolved, take food after 2 days gruel, noodles, normally feed after 10 days, CT film making tumor body disappears after January, 10 years so far healthy livings still.
3, profound scholar's perfume (or spice), the woman, 64 years old, Daiyue District Liang Zhuan town, Tai, Shandong Province prolongs East Village greatly, be diagnosed as esophageal carcinoma in Shandong Province Xin Wen city colliery hospital through CT examination because of carrying out property dysphagia in January, 2000, this institute do two the course of treatment chemotherapy, check CT tumor body do not see and dwindles, February 15 the same year this pill of containing, when containing the 8th ball, the white thick secretions of courageous and upright reddish yellow spues, carcinoma is dissolved when containing 18 balls, the 2nd day noodles that can drink bean milk, normally feed after 7 days, so far 5 years still alive, and carcinoma is found at the CT examination end.
4, Li Xiuying, the woman, 68 years old, Xintai City Quan Gou town, Shandong Province Yang Zhuan people from village, do scope and pathologic finding because of the difficulty of taking food in the Xintai City the People's Hospital and be diagnosed as distal esophagus 1/4 carcinoma in April, 1988, through 3 the course of treatment chemotherapy, tumor body end disappears, and contains this pill because of side effect changes too greatly, the white thick liquid of reddish yellow spues when containing 6, feed noodles during 18 balls, normally feed after 10 days, still alive so far.
5, Zhang Zhaoying, the woman, 49 years old Ningyang County of Shandong Province Dong Zhuan township Da Zhangjia people from village, in JIUYUE, 1998 is because of dysphagia 1/3 place's tumor body under Ningyang County hospital CT examination is diagnosed as in the esophagus, through 4 the course of treatment chemotherapy, no significant change, this pill of containing contains the 6th ball courageous and upright thick secretions that spues, the tumor body disappears when containing to 20 balls, normally feed after 10 days, surplus still healthy survival in 7 years so far, the tumor body is found at the CT examination end.
6, Wang Qinghua, the man, 68 years old, Tai, Shandong Province Daiyue District Wen Kou Zhen Ercun made a definite diagnosis esophagus stage casing 1/4 tumor body through esophagoscope of the People's Hospital, Tai and pathologic finding in 2003, and courageous and upright thick secretions spues behind 6 of this pills of containing, containing disappears to 18 tumor bodies, feed milk noodles after 2 days, normally feed after 12 days, still healthy survival more than 2 years.
7, Wang Chunlei, the man, 69 years old, Wang Jiayao village, Xintai City Quan Gou town, Shandong Province from factory, April calendar year 2001, carrying out property dysphagia was diagnosed as the esophagus carcinoma in Xintai City the People's Hospital row scope and pathologic finding, through the court 2 the course of treatment chemotherapy do not have obvious improvement, the white thick secretions of reddish yellow that spues during 7 of this pills of containing is when containing 22, the tumor body dissolves, can take food milk, noodles, normally feed after 14 days, still alive so far.
Use this pill points for attention:
Preparation of the present invention belongs to oral buccal medicine ball, spues after the containing, and avoids and swallows.
Usage and consumption:
Esophagus carcinoma severe patient containing a half an hour ball, every day containing 24 balls, approximately after containing 2-4 days, there is the red white xanchromatic compounding substances of sticking foam and mucus consistence to spue, at this moment tumor has been dissolved and has been broken apart, and changes 3 hours containing balls after taking food into, and containing promptly stopped in 3 days continuously.
Claims (5)
1, a kind of Chinese medicine for the treatment of esophageal carcinoma is characterized in that it mainly is the medicine pill of being made by following bulk drugs: Lapis Micae Aureus 40-70 part, Borax 60-85 part, Sal Ammoniacus 60-85 part, Cornu Saigae Tataricae 25-50 part, Borneolum Syntheticum 65-85 part, Chalcanthitum 50-75 part, Lignum Aquilariae Resinatum 70-90 part, Venenum Bufonis 55-75 part, Squama Manis 65-85 part, Calculus Bovis 50-70 part, Moschus 35-55 part, Oleum Sesami 150-220 part.
2, according to the Chinese medicine of the treatment esophageal carcinoma of claim 1, it is characterized in that it mainly is the medicine pill of being made by following raw material: Lapis Micae Aureus 45-65 part, Borax 65-80 part, Sal Ammoniacus 65-80 part, Cornu Saigae Tataricae 30-45 part, Borneolum Syntheticum 70-85 part, Chalcanthitum 55-70 part, Lignum Aquilariae Resinatum 75-90 part, Venenum Bufonis 60-75 part, Squama Manis 65-75 part, Calculus Bovis 50-65 part, Moschus 40-55 part, Oleum Sesami 180-210 part.
3, according to claim, the described pellet of choking of dispelling is the Chinese medicine pill agent of being manufactured by weight by following material combination: Lapis Micae Aureus 50-60 part, Borax 65-75 part, Sal Ammoniacus 65-75 part, Cornu Saigae Tataricae 35-45 part, Borneolum Syntheticum 60-75 part, Chalcanthitum 55-70 part, Lignum Aquilariae Resinatum 60-75 part, Venenum Bufonis 55-65 part, Squama Manis 55-75 part, Calculus Bovis 40-55 part, Moschus 45-60 part, Oleum Sesami 140-190 part.
4, according to claim, the described pellet of choking of dispelling is the medicine pill of being manufactured by following raw material: 60 parts of Lapis Micae Aureuss, 70 parts of Boraxs, 75 parts of Sal Ammoniacuss, 40 parts of Cornu Saigae Tataricae, 75 parts of Borneolum Syntheticums, 60 parts in Chalcanthitum, 75 parts of Lignum Aquilariae Resinatum, 65 parts of Venenum Bufoniss, 70 parts of Squama Maniss, 60 parts of Calculus Boviss, 45 parts in Moschus, 200 parts in Oleum Sesami.
5, a kind of red compound method of choking of dispelling of claim 1:
(1) at first weigh up the Chinese medicine of respectively distinguishing the flavor of by proportioning raw materials: Sal Ammoniacus is worn into the powder face, put into marmite, (noting: keep away metal) added water boil about 20 minutes, crossed and filtered to remove medicinal residues, continued to employ clean Sal Ammoniacus liquid;
(2) Sal Ammoniacus liquid is poured in the marmite added vinegar again in marmite, add the vinegar amount for being stirred to burning marmite, the limit stirs evenly, and fire decocts to the charcoal yellow crystals and is degree;
(3) be stirred into sticky shape cream liquid, temperature 60-80 ℃ with adding the Oleum Sesami that weighs up in the charcoal yellow crystals;
(4) in above-mentioned sticky shape cream liquid, add, the Lapis Micae Aureus that weighs up, Borax, Cornu Saigae Tataricae, Borneolum Syntheticum, Chalcanthitum, Lignum Aquilariae Resinatum is looked forward or upwards shortcake, Squama Manis, Calculus Bovis, after the Moschus powder mixes stirred evenly, at this moment ceasing fire cooled;
(5) the Oleum sesami mix homogeneously that the Chinese medicine plaster that cools go into to claim is grown permanent teeth, with hands group become ball pill of the present invention.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2006100444046A CN101036732B (en) | 2006-03-02 | 2006-03-02 | Chinese medicine preparation for esophagus cancer and its compounding process |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2006100444046A CN101036732B (en) | 2006-03-02 | 2006-03-02 | Chinese medicine preparation for esophagus cancer and its compounding process |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN101036732A true CN101036732A (en) | 2007-09-19 |
| CN101036732B CN101036732B (en) | 2011-03-16 |
Family
ID=38888040
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN2006100444046A Expired - Fee Related CN101036732B (en) | 2006-03-02 | 2006-03-02 | Chinese medicine preparation for esophagus cancer and its compounding process |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN101036732B (en) |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101347459B (en) * | 2008-09-10 | 2013-01-02 | 刘皇琼 | Medicine for treating cancer |
| CN104474161A (en) * | 2014-12-13 | 2015-04-01 | 李菲 | Blood stasis-removing powder for treating esophageal cancer and preparation method of blood stasis-removing powder |
| CN114366768A (en) * | 2022-01-30 | 2022-04-19 | 河北省疾控医学科学研究所 | Medicine composition for treating esophageal cancer and preparation method thereof |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104940436A (en) * | 2015-05-27 | 2015-09-30 | 刘保安 | Traditional Chinese medicine composition for treating esophagus cancer |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1243710A (en) * | 1999-01-28 | 2000-02-09 | 金建社 | Medicine for treating esophageal obstruction caused by esophagus cancer and its preparing process |
| CN1298359C (en) * | 2002-11-21 | 2007-02-07 | 杜仰恩 | Chinese patent medicine for treating esophagus cancer |
-
2006
- 2006-03-02 CN CN2006100444046A patent/CN101036732B/en not_active Expired - Fee Related
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101347459B (en) * | 2008-09-10 | 2013-01-02 | 刘皇琼 | Medicine for treating cancer |
| CN104474161A (en) * | 2014-12-13 | 2015-04-01 | 李菲 | Blood stasis-removing powder for treating esophageal cancer and preparation method of blood stasis-removing powder |
| CN114366768A (en) * | 2022-01-30 | 2022-04-19 | 河北省疾控医学科学研究所 | Medicine composition for treating esophageal cancer and preparation method thereof |
Also Published As
| Publication number | Publication date |
|---|---|
| CN101036732B (en) | 2011-03-16 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN101884770A (en) | Chinese medicinal preparation for treating urolithiasis and preparation method thereof | |
| CN102526616A (en) | Chinese medicinal herb pills for treating cholecystitis and gallstone | |
| CN102188685B (en) | Externally-applied traditional Chinese medicine powder for treating diarrhea type irritable bowel syndrome and preparation method thereof | |
| CN100574784C (en) | A kind of Chinese medicine composition of orally taken for curing bacillary dysentery | |
| CN101036732B (en) | Chinese medicine preparation for esophagus cancer and its compounding process | |
| CN102078549B (en) | Traditional Chinese medicine for treating oxyuriasis | |
| CN102872362B (en) | Traditional Chinese medicine for treating chronic cholecystitis | |
| CN104587206A (en) | Medicament for treating bedsore and preparation method of medicament | |
| CN101549025B (en) | Traditional Chinese medicine for treating cancer | |
| CN103585585A (en) | Traditional Chinese medicine composition for treating choledocholithiasis and preparation method thereof | |
| CN100534505C (en) | Chinese-medicinal powder for treating acne | |
| CN103877384B (en) | A kind of Chinese medicine preparation and preparation method who treats the carcinoma of the rectum | |
| CN103520638B (en) | A kind of Traditional Chinese medicine compound composition for the treatment of prostate hyperplasia and preparation method thereof and application thereof | |
| CN103566118B (en) | A kind of medicine and preparation method for the treatment of chronic nephritis | |
| CN107913402A (en) | A kind of combination of Chinese tradiational and Western medicine medicine for treating atrophic gastritis and preparation method | |
| CN101804142B (en) | Traditional Chinese medicine composition for treating carcinoma of uterine body | |
| CN106975044A (en) | It is a kind of to treat medicine of calculus and its preparation method and application | |
| CN1088378C (en) | Oral Chinese medicine liquid for treating chronic superficial gastritis and its preparation | |
| CN105213655A (en) | A kind of Chinese medicine composition of adjuvant treatment of acute cholecystitis | |
| CN105079771A (en) | Traditional Chinese medicine composition for treating postoperatively adhesive intestinal obstruction | |
| CN104984305B (en) | A kind of Chinese medicine composition for treating chronic cholecystitis | |
| CN104138477B (en) | It is a kind of to be used to treat Chinese medicine composition of calculus and preparation method thereof | |
| CN112741865A (en) | Medicine formula for treating esophagus cancer, preparation method and application | |
| CN103690901A (en) | Traditional Chinese medicine for treating cholelithiasis and preparation method thereof | |
| CN117159642A (en) | Pill for nourishing yin and relaxing bowels |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| ASS | Succession or assignment of patent right |
Owner name: XUE LIXIANG Free format text: FORMER OWNER: FANG CHANGHE Effective date: 20120425 |
|
| C41 | Transfer of patent application or patent right or utility model | ||
| TR01 | Transfer of patent right |
Effective date of registration: 20120425 Address after: 271000 No. seven Li 107, Taishan District, Shandong, Tai'an, China Patentee after: Xue Lixiang Address before: 271000 Tai'an Tumor Hospital of Shandong Province Patentee before: Fang Changhe |
|
| ASS | Succession or assignment of patent right |
Owner name: XIU ZHIMING Effective date: 20130220 |
|
| C41 | Transfer of patent application or patent right or utility model | ||
| TR01 | Transfer of patent right |
Effective date of registration: 20130220 Address after: 271000 No. seven Li 107, Taishan District, Shandong, Tai'an, China Patentee after: Xue Lixiang Patentee after: Xiu Zhiming Address before: 271000 No. seven Li 107, Taishan District, Shandong, Tai'an, China Patentee before: Xue Lixiang |
|
| DD01 | Delivery of document by public notice |
Addressee: Xiu Zhiming Document name: Notification to Pay the Fees |
|
| DD01 | Delivery of document by public notice | ||
| DD01 | Delivery of document by public notice |
Addressee: Xiu Zhiming Document name: Notification of Termination of Patent Right |
|
| DD01 | Delivery of document by public notice | ||
| CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20110316 Termination date: 20170302 |
|
| CF01 | Termination of patent right due to non-payment of annual fee |