CN101023974A - Preparing method for honeysuckle paste - Google Patents
Preparing method for honeysuckle paste Download PDFInfo
- Publication number
- CN101023974A CN101023974A CN 200610008300 CN200610008300A CN101023974A CN 101023974 A CN101023974 A CN 101023974A CN 200610008300 CN200610008300 CN 200610008300 CN 200610008300 A CN200610008300 A CN 200610008300A CN 101023974 A CN101023974 A CN 101023974A
- Authority
- CN
- China
- Prior art keywords
- chlorogenic acid
- preparation
- honeysuckle
- honeysuckle paste
- percolation
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Landscapes
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
The present invention relates to a preparation method of lonicera flower extract. Said preparation method includes the following steps: soaking lonicera flower in NaOH solution whose concentration is 0.0625%, diacolation and reduced pressure concentration to make the relative density of liquid medicine be 1.17-1.20, and make the chlorogenic acid content in the lonicera flower extract be controlled in 20 mg- 30 mg/g.
Description
Technical field: this utility model relates to a kind of preparation method of honeysuckle paste, makes that chlorogenic acid contents is controlled at 20mg～30mg/g in the honeysuckle paste.
Background technology:
Flos Lonicerae is the alabastrum of Caprifoliaceae Radix Ophiopogonis Lonicera japonica Thunb plant drying, wants for traditional Chinese medical science medicine commonly used, has the function of heat-clearing and toxic substances removing, cool breeze heat radiation, antiviral, hepatic cholagogic.Its main active is chlorogenic acid, flavone etc.Tradition experience and modern pharmacology experiment and clinically prove that all Flos Lonicerae has stronger antibacterial action and better therapeutic effect for multiple pathogenic bacteria.The making of honeysuckle paste in the compound recipe Flos Lonicerae oral formulations production process, especially controlling chlorogenic acid contents in the honeysuckle paste is the guarantee of control oral quality of compound recipe Flos Lonicerae and curative effect.
At present, the method for known chlorogenic acid extracting has following several:
1). water extraction: crude drug decocts 2 times with 10 times and 8 times of water gagings, each 2h, merge extractive liquid,, filter be evaporated to dried.
2). decoction and alcohol sedimentation technique: crude drug decocts 2 times with 10 times and 8 times of water gagings, each 2h, merge extractive liquid, filters and was evaporated to 1: 1 o'clock, adds ethanol to content and reaches 80%, leaves standstill, and filters, and is evaporated to dried.
3). rare alcohol extraction is followed the example of: crude drug is measured 70% ethanol extraction 2 times with 10 times and 8 times, each 2h, extracting solution merges filtration, is evaporated to dried.
4). the acid alcohol extraction method: 3～4 70% ethanol extraction 2 times, each 2h, extracting solution merge and filter crude drug, are evaporated to dried with 10 times and 8 times amount pH value.
5). the defat alcohol extracting method: after ether merceration 2h defat, with 95% ethanol extraction 24h, repeat 2 times, merging filtrate is evaporated to dried.
6). ultrasonic extraction: this method is in conjunction with on the above-mentioned basis, only improves the extraction ratio of chlorogenic acid by ultrasound wave, can only be as breadboard research method, and can't be widely used in the production.
Main antipathogenic composition in the Flos Lonicerae is for being chlorogenic acid, judges the method for chlorogenic acid extracting from Flos Lonicerae according to the height of chlorogenic acid yield, be better than water extraction with alcohol extracting method, and the decoction and alcohol sedimentation technique effect is relatively poor.The method that above extracting method can be applied in commercial production is mainly water extraction and alcohol extracting method, all there are certain pluses and minuses in the two, the water extraction advantage is that solvent cost is low, extraction time is short, the extractum extraction ratio is higher, shortcoming is that to extract impurity more, more number of times just chlorogenic acid can be extracted extreme value, and ambient temperature is higher when extracting simultaneously easily causes the chlorogenic acid oxidation.The shortcoming of alcohol extracting method is that solvent cost is higher, and liposoluble constituent increases in the extract, and advantage is that extraction impurity is less, chlorogenic acid extraction ratio height, and extraction temperature gentleness is difficult for causing the chlorogenic acid oxidation, especially under sour environment.
Summary of the invention:
For the temperature that solves water extraction higher, the solvent cost problem of higher of alcohol extracting method, the technical solution adopted in the utility model is: with a kind of low concentration alkalescence solvent NaH solution, carry out percolation and extract.Concrete grammar is: crude drug floods, percolation, is evaporated to relative density of medicine liquid 1.17～1.20 with 0.0625% NaOH solution of 16 times of amounts.
Beneficial effect:
The beneficial effects of the utility model are, mode that can cold extraction, with the chlorogenic acid in the alkali liquor extraction Flos Lonicerae of low concentration, guarantee that prepared honeysuckle paste can extract the chlorogenic acid in the Flos Lonicerae to greatest extent, make that chlorogenic acid contents is controlled at 20mg～30mg/g in the honeysuckle paste, and cost is low, the efficient height.
The specific embodiment:
Get 0.0625% NaOH caustic dip liquid and flood crude drug and exceed medical material 30cm, soaked 24 hours, the beginning percolation, extremely to the alkali liquor of using up 16 times of amounts, the used time is 72 hours, collects alkali liquor, become final relative density of medicine liquid 1.17～1.20 with concentrating under reduced pressure, measure chlorogenic acid contents.
Claims (3)
1. the preparation method of a honeysuckle paste makes chlorogenic acid contents be controlled at 20mg～30mg/g.It is characterized in that: adopt a kind of low concentration alkalescence solvent NaH solution, carry out percolation and extract.
2. the preparation method of a kind of honeysuckle paste according to claim 1, it is characterized in that: the alkali liquor of the low concentration of employing is 0.0625% NaOH solution, make a living 16 times of dose of solution usage, dip time is 24 hours, total percolation time is 72 hours.
3. the preparation method of a kind of honeysuckle paste according to claim 1, it is characterized in that: adopt 0.0625% NaOH solution, to Flos Lonicerae flood, percolation, concentrating under reduced pressure become cream, relative density of medicine liquid is 1.17～1.20, and chlorogenic acid contents is controlled at 20mg～30mg/g in the honeysuckle paste.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 200610008300 CN101023974A (en) | 2006-02-22 | 2006-02-22 | Preparing method for honeysuckle paste |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 200610008300 CN101023974A (en) | 2006-02-22 | 2006-02-22 | Preparing method for honeysuckle paste |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN101023974A true CN101023974A (en) | 2007-08-29 |
Family
ID=38742816
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN 200610008300 Pending CN101023974A (en) | 2006-02-22 | 2006-02-22 | Preparing method for honeysuckle paste |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN101023974A (en) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102488284A (en) * | 2011-12-26 | 2012-06-13 | 广西万寿堂药业有限公司 | Honeysuckle drink and preparation method thereof |
| CN112724115A (en) * | 2020-12-24 | 2021-04-30 | 广州城市职业学院 | Firecracker spark cream and preparation method thereof |
-
2006
- 2006-02-22 CN CN 200610008300 patent/CN101023974A/en active Pending
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102488284A (en) * | 2011-12-26 | 2012-06-13 | 广西万寿堂药业有限公司 | Honeysuckle drink and preparation method thereof |
| CN102488284B (en) * | 2011-12-26 | 2013-12-11 | 广西万寿堂药业有限公司 | Honeysuckle drink and preparation method thereof |
| CN112724115A (en) * | 2020-12-24 | 2021-04-30 | 广州城市职业学院 | Firecracker spark cream and preparation method thereof |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN102293724A (en) | Cosmetic composition containing Chinese herbal compounds | |
| CN106236808B (en) | A kind of stevia rebaudiana phenol extract and its application in anti-inflammatory product | |
| CN100465183C (en) | Method of comprehensive utilizing schisandra fruit | |
| CN101288485A (en) | Honeysuckle health-care beverage | |
| KR101128564B1 (en) | The manufacturing process of lithospermum erythrorhizon soap controlled by vineger | |
| CN102961318B (en) | Application of compound traditional Chinese medicine extract in preparation of oral care health products | |
| CN102138887A (en) | Multifunctional compound golden thread Chinese medicinal herb toothpaste | |
| CN107412085A (en) | A kind of dendrobium candidum toothpaste and preparation method thereof | |
| Dai et al. | Honey in traditional Chinese medicine: A guide to future applications of NADES to medicines | |
| CN108653081B (en) | Compound golden camellia mouthwash and preparation method thereof | |
| CN101023974A (en) | Preparing method for honeysuckle paste | |
| CN102319354B (en) | Heat clearing and detoxication oral liquid, and preparation method thereof | |
| CN102048910A (en) | Honeysuckle oral liquid | |
| CN111568952A (en) | Concentrated Shuanghuanglian oral liquid preparation for production and preparation method thereof | |
| CN103505395B (en) | Forsythia leaf traditional Chinese medicinal toothpaste | |
| CN103520012A (en) | Application of baicalin in preparation of oral care product | |
| CN105434262A (en) | Largetrifoliolious-bugbane-rhizome toothpaste | |
| CN102618420A (en) | Health-care liquor and manufacturing method thereof | |
| CN105362127A (en) | Anti-inflammation and haemostatic medicinal toothpaste | |
| CN110215427A (en) | It is a kind of to have effects that the composition of whitening antioxidation and its face cream | |
| KR20150024502A (en) | A cosmetic composition for preventing and improving skin winkle | |
| KR20160068215A (en) | Cosmetic Compositions Including a Natural Extract for Improvement of Acne | |
| CN104127356B (en) | A kind of Fructus Hippophae oropharynx anti-inflammation combination liquid and preparation method thereof | |
| CN110115737A (en) | Plant the application on tooth Chinese medicine nursing liquid, preparation method and plant tooth | |
| CN101439008A (en) | Women's washing lotion |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C02 | Deemed withdrawal of patent application after publication (patent law 2001) | ||
| WD01 | Invention patent application deemed withdrawn after publication |