CN101023947B - 用于杀菌、抑菌和抗炎的组合物及其方法 - Google Patents
用于杀菌、抑菌和抗炎的组合物及其方法 Download PDFInfo
- Publication number
- CN101023947B CN101023947B CN2006101121600A CN200610112160A CN101023947B CN 101023947 B CN101023947 B CN 101023947B CN 2006101121600 A CN2006101121600 A CN 2006101121600A CN 200610112160 A CN200610112160 A CN 200610112160A CN 101023947 B CN101023947 B CN 101023947B
- Authority
- CN
- China
- Prior art keywords
- macrophage
- cell
- dextromethorphan
- lps
- tnf
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/01—Hydrocarbons
- A61K31/015—Hydrocarbons carbocyclic
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/485—Morphinan derivatives, e.g. morphine, codeine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/10—Anti-acne agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Epidemiology (AREA)
- Dermatology (AREA)
- Emergency Medicine (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
Abstract
Description
DM(ppm) | 5000 | 2500 | 1250 | 1000 | 500 | 250 | 125 |
DM百分比(%) | 5 | 2.5 | 1.25 | 1 | 0.5 | 0.25 | 0.125 |
生长抑制 | + | + | + | + | + |
DM(ppm) | 5000 | 2500 | 1250 | 1000 | 500 | 阴性对照 |
DM百分比(%) | 5 | 2.5 | 1.25 | 0.6 | 0.3 | |
生长抑制 | + | + | + |
Claims (1)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US11/361,589 | 2006-02-24 | ||
US11/361,589 US7939567B2 (en) | 2006-02-24 | 2006-02-24 | Dextromethorphan-based method for treating acne |
Publications (2)
Publication Number | Publication Date |
---|---|
CN101023947A CN101023947A (zh) | 2007-08-29 |
CN101023947B true CN101023947B (zh) | 2012-10-31 |
Family
ID=38437685
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CN2006101121600A Active CN101023947B (zh) | 2006-02-24 | 2006-08-15 | 用于杀菌、抑菌和抗炎的组合物及其方法 |
Country Status (13)
Country | Link |
---|---|
US (1) | US7939567B2 (zh) |
EP (1) | EP1986620B1 (zh) |
JP (1) | JP5347195B2 (zh) |
KR (1) | KR101279196B1 (zh) |
CN (1) | CN101023947B (zh) |
AT (1) | ATE539749T1 (zh) |
AU (1) | AU2006338583B8 (zh) |
BR (1) | BRPI0621210A2 (zh) |
CA (1) | CA2643277A1 (zh) |
IL (1) | IL193628A0 (zh) |
TW (1) | TWI365743B (zh) |
WO (1) | WO2007097765A1 (zh) |
ZA (1) | ZA200806703B (zh) |
Families Citing this family (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US8461102B2 (en) * | 2010-03-02 | 2013-06-11 | George E. Royster, JR. | Methods and compositions for treating and preventing symptoms of hormonal variations |
RU2571284C2 (ru) * | 2010-05-03 | 2015-12-20 | Тсх Биофарм Корпорейшн, Лимитед | Фармацевтическая композиция и способ лечения гипертензии |
SG194420A1 (en) * | 2010-05-27 | 2013-12-30 | Kenichiro Hasumi | Antigen peptide and use thereof |
WO2013016480A1 (en) | 2011-07-28 | 2013-01-31 | Zagon Ian S | Methods and compositions for treatment of epithelial wounds |
EP2945627A4 (en) * | 2013-01-21 | 2016-11-30 | Avant Derma Pte Ltd | USE OF DELTA-OPIOID RECEPTOR SELECTIVE ANTAGONISTS AND SENSORY RECEPTOR-SPECIFIC LIGANDS |
US9649266B2 (en) * | 2014-05-01 | 2017-05-16 | Anterios, Inc. | Methods to treat, prevent, and improve skin conditions |
BR112019010131A2 (pt) | 2016-11-21 | 2019-10-08 | Eirion Therapeutics Inc | entrega transdérmica de agentes grandes |
CN106801037B (zh) * | 2017-01-06 | 2021-01-19 | 中国人民解放军***福州总医院 | 体外痤疮炎症模型的建立方法及其应用 |
WO2020123194A1 (en) * | 2018-12-11 | 2020-06-18 | Kristoffer Hellstrand | Methods of reducing post-surgical metastasis |
CN114409673B (zh) * | 2022-01-04 | 2023-08-08 | 广东克冠达医药科技有限公司 | 一种***喃类化合物及其制备方法与应用 |
Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5834480A (en) * | 1997-06-13 | 1998-11-10 | Elkhoury; George F. | Topical application of opioids for treatment of acne and sebaceous gland disorders |
CN1423559A (zh) * | 2000-02-08 | 2003-06-11 | 欧罗赛铁克股份有限公司 | 包含阿片样激动剂和拮抗剂的控释组合物 |
CN1449755A (zh) * | 2003-01-23 | 2003-10-22 | 张以成 | 氢溴酸右美沙芬滴丸及其制备方法 |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US2676177A (en) | 1949-11-09 | 1954-04-20 | Hoffmann La Roche | Process for the preparation of optically active 3-methoxy-n-methyl morphinans and salts thereof |
CA1214393A (en) * | 1984-06-26 | 1986-11-25 | Eric L. Nelson | Composition useful in the treatment of diarrhea |
DE69229454T2 (de) * | 1991-03-28 | 2000-01-05 | Merck & Co., Inc. | Untereinheit-C des vaskulären endothelialen Zellwachstumsfaktors |
US5206248A (en) | 1992-03-27 | 1993-04-27 | Smith Richard A | Method for reducing emotional lability |
US5366980A (en) | 1991-06-17 | 1994-11-22 | Smith Richard A | Use of dextromethorphan and an oxidase inhibitor to treat dermatitis |
US5260066A (en) | 1992-01-16 | 1993-11-09 | Srchem Incorporated | Cryogel bandage containing therapeutic agent |
US5994330A (en) * | 1998-11-09 | 1999-11-30 | El Khoury; Georges F. | Topical application of muscarinic agents such as neostigmine for treatment of acne and other inflammatory conditions |
-
2006
- 2006-02-24 US US11/361,589 patent/US7939567B2/en active Active
- 2006-03-07 TW TW095107622A patent/TWI365743B/zh active
- 2006-04-26 EP EP06751392A patent/EP1986620B1/en active Active
- 2006-04-26 BR BRPI0621210-7A patent/BRPI0621210A2/pt not_active IP Right Cessation
- 2006-04-26 AU AU2006338583A patent/AU2006338583B8/en active Active
- 2006-04-26 KR KR1020087020105A patent/KR101279196B1/ko active IP Right Grant
- 2006-04-26 JP JP2008556294A patent/JP5347195B2/ja active Active
- 2006-04-26 CA CA002643277A patent/CA2643277A1/en not_active Abandoned
- 2006-04-26 AT AT06751392T patent/ATE539749T1/de active
- 2006-04-26 WO PCT/US2006/015661 patent/WO2007097765A1/en active Search and Examination
- 2006-08-15 CN CN2006101121600A patent/CN101023947B/zh active Active
-
2008
- 2008-08-01 ZA ZA200806703A patent/ZA200806703B/xx unknown
- 2008-08-21 IL IL193628A patent/IL193628A0/en unknown
Patent Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5834480A (en) * | 1997-06-13 | 1998-11-10 | Elkhoury; George F. | Topical application of opioids for treatment of acne and sebaceous gland disorders |
CN1423559A (zh) * | 2000-02-08 | 2003-06-11 | 欧罗赛铁克股份有限公司 | 包含阿片样激动剂和拮抗剂的控释组合物 |
CN1449755A (zh) * | 2003-01-23 | 2003-10-22 | 张以成 | 氢溴酸右美沙芬滴丸及其制备方法 |
Also Published As
Publication number | Publication date |
---|---|
ATE539749T1 (de) | 2012-01-15 |
AU2006338583B8 (en) | 2012-01-12 |
AU2006338583B2 (en) | 2011-12-22 |
EP1986620B1 (en) | 2012-01-04 |
US20070203164A1 (en) | 2007-08-30 |
CA2643277A1 (en) | 2007-08-30 |
KR20080106183A (ko) | 2008-12-04 |
KR101279196B1 (ko) | 2013-06-26 |
ZA200806703B (en) | 2009-09-30 |
BRPI0621210A2 (pt) | 2011-12-06 |
AU2006338583A1 (en) | 2007-08-30 |
TW200731972A (en) | 2007-09-01 |
EP1986620A1 (en) | 2008-11-05 |
CN101023947A (zh) | 2007-08-29 |
TWI365743B (en) | 2012-06-11 |
WO2007097765A1 (en) | 2007-08-30 |
US7939567B2 (en) | 2011-05-10 |
JP2009527553A (ja) | 2009-07-30 |
IL193628A0 (en) | 2009-08-03 |
EP1986620A4 (en) | 2009-11-25 |
JP5347195B2 (ja) | 2013-11-20 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
CN101023947B (zh) | 用于杀菌、抑菌和抗炎的组合物及其方法 | |
US11103471B2 (en) | Antimicrobials and methods of use thereof | |
AU2019229354B2 (en) | Volatile organic compound formulations having antimicrobial activity | |
WO2008104076A1 (en) | Electrocolloidal silver and echinacea root antimicrobial formulation | |
TWI825362B (zh) | 乳酸菌醱酵產物用於製備促進皮膚創傷癒合之外用組成物的用途 | |
JPH06503806A (ja) | 胃腸疾病を処置するための5―ジフルオロメトキシ―2―[(3,4―ジメトキシ―2―ピリジル)メチルスルフィニル]ベンズイミダゾール及び抗ヘリコバクター剤含有医薬組成物 | |
WO2013191565A1 (en) | Antimicrobial composition and its method of use | |
CN103202881A (zh) | 一种治疗皮疹的外用剂组合物 | |
Butler et al. | Intravenous histamine in the treatment of migraine: Preliminary observations | |
KR100375342B1 (ko) | 위장 질환 개선을 위한 천연 항균물질 조성물 | |
EP1312364A1 (en) | Cytokine production inhibitors | |
CN114767701B (zh) | 一种用于治疗痤疮的药物及其用途 | |
CN115252594A (zh) | 山椒素在制备抗痤疮丙酸杆菌的药物中的用途 | |
CA2441629C (en) | Antibiotic pharmaceutical composition with lysergol as bio-enhancer and method of treatment | |
CN115869385A (zh) | 天然产物诺卡酮协同增效多黏菌素在抗革兰氏阴性细菌感染中的应用 | |
Josephs et al. | Drug-drug interaction may explain failed antibiotic effectiveness-an in vivo study | |
JP2001199885A (ja) | 抗菌剤 | |
WO2019240677A2 (en) | Composition of vitamin c and vitamin e with rifampicin for the treatment of all infected wounds and all dermatological problems either infected or at risk of being infected | |
Yin et al. | Topical probiotics in wound care: a review of effects, mechanisms and applications | |
JP2001139467A (ja) | 上皮形成促進剤 |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
C06 | Publication | ||
PB01 | Publication | ||
C10 | Entry into substantive examination | ||
SE01 | Entry into force of request for substantive examination | ||
ASS | Succession or assignment of patent right |
Free format text: FORMER OWNER: SU HUIBIN WU HUALIN SHI GUIYUE Owner name: BLUE BLOOD BIOTECH. CORP. Free format text: FORMER OWNER: JIANG ZHUANJI Effective date: 20110718 |
|
C41 | Transfer of patent application or patent right or utility model | ||
C53 | Correction of patent of invention or patent application | ||
CB03 | Change of inventor or designer information |
Inventor after: Wu Hualin Inventor after: Shi Guiyue Inventor before: Jiang Chuanji Inventor before: Su Huibin Inventor before: Wu Hualin Inventor before: Shi Guiyue |
|
COR | Change of bibliographic data |
Free format text: CORRECT: ADDRESS; FROM: BUILDING 3, NO. 55, FRONT STREET, NEIGHBORHOOD 11, JIUJIALI, SHILIN DISTRICT, TAIPEI CITY, TAIWAN, CHINA TO: 11070 BUILDING 2, NO. 53, DONGXING ROAD, TAIPEI CITY, TAIWAN PROVINCE, CHINA |
|
TA01 | Transfer of patent application right |
Effective date of registration: 20110718 Address after: Eleven thousand and seventy 2 floor, No. 53, Dongxing Road, Taipei, Taiwan, China Applicant after: Precious Blood Purification Technology Co.,Ltd. Address before: Good old Chinese Taiwan Shilin District in Taipei city and 11 adjacent St. 55 3 floor Applicant before: Jiang Chuanji Co-applicant before: Su Huibin Co-applicant before: Wu Hualin Co-applicant before: Shi Guiyue |
|
C14 | Grant of patent or utility model | ||
GR01 | Patent grant |