CN101019898A - Crushing method and prepn of aweto - Google Patents
Crushing method and prepn of aweto Download PDFInfo
- Publication number
- CN101019898A CN101019898A CN 200710048651 CN200710048651A CN101019898A CN 101019898 A CN101019898 A CN 101019898A CN 200710048651 CN200710048651 CN 200710048651 CN 200710048651 A CN200710048651 A CN 200710048651A CN 101019898 A CN101019898 A CN 101019898A
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- China
- Prior art keywords
- polypide
- cordyceps
- stroma
- preparation
- orders
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- 238000000034 method Methods 0.000 title claims abstract description 23
- 238000002360 preparation method Methods 0.000 claims abstract description 31
- 235000013305 food Nutrition 0.000 claims abstract description 7
- 241000190633 Cordyceps Species 0.000 claims description 42
- 238000010298 pulverizing process Methods 0.000 claims description 18
- 239000000203 mixture Substances 0.000 claims description 7
- 239000007788 liquid Substances 0.000 claims description 6
- 239000002775 capsule Substances 0.000 claims description 5
- 239000003826 tablet Substances 0.000 claims description 5
- 235000013402 health food Nutrition 0.000 claims description 4
- 239000000843 powder Substances 0.000 claims description 4
- 239000007787 solid Substances 0.000 claims description 4
- 239000002671 adjuvant Substances 0.000 claims description 3
- 238000009472 formulation Methods 0.000 claims description 3
- 239000006187 pill Substances 0.000 claims description 3
- 230000000295 complement effect Effects 0.000 claims description 2
- 239000003814 drug Substances 0.000 abstract description 4
- 239000000835 fiber Substances 0.000 abstract description 4
- 238000010438 heat treatment Methods 0.000 abstract 1
- 230000002045 lasting effect Effects 0.000 abstract 1
- 239000004615 ingredient Substances 0.000 description 4
- 210000004027 cell Anatomy 0.000 description 3
- 230000001413 cellular effect Effects 0.000 description 3
- 206010011224 Cough Diseases 0.000 description 2
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 2
- 241000330899 Hepialus Species 0.000 description 2
- 239000013543 active substance Substances 0.000 description 2
- 230000007812 deficiency Effects 0.000 description 2
- 230000000694 effects Effects 0.000 description 2
- 238000000227 grinding Methods 0.000 description 2
- 210000003734 kidney Anatomy 0.000 description 2
- 210000004072 lung Anatomy 0.000 description 2
- 239000002245 particle Substances 0.000 description 2
- GUBGYTABKSRVRQ-XLOQQCSPSA-N Alpha-Lactose Chemical compound O[C@@H]1[C@@H](O)[C@@H](O)[C@@H](CO)O[C@H]1O[C@@H]1[C@@H](CO)O[C@H](O)[C@H](O)[C@H]1O GUBGYTABKSRVRQ-XLOQQCSPSA-N 0.000 description 1
- 241000208340 Araliaceae Species 0.000 description 1
- 241001480006 Clavicipitaceae Species 0.000 description 1
- 208000000059 Dyspnea Diseases 0.000 description 1
- 206010013975 Dyspnoeas Diseases 0.000 description 1
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 description 1
- 241000130660 Hepialidae Species 0.000 description 1
- 206010062717 Increased upper airway secretion Diseases 0.000 description 1
- GUBGYTABKSRVRQ-QKKXKWKRSA-N Lactose Natural products OC[C@H]1O[C@@H](O[C@H]2[C@H](O)[C@@H](O)C(O)O[C@@H]2CO)[C@H](O)[C@@H](O)[C@H]1O GUBGYTABKSRVRQ-QKKXKWKRSA-N 0.000 description 1
- 241001248610 Ophiocordyceps sinensis Species 0.000 description 1
- 235000005035 Panax pseudoginseng ssp. pseudoginseng Nutrition 0.000 description 1
- 235000003140 Panax quinquefolius Nutrition 0.000 description 1
- 229920002472 Starch Polymers 0.000 description 1
- 239000004480 active ingredient Substances 0.000 description 1
- 125000003275 alpha amino acid group Chemical group 0.000 description 1
- 235000001014 amino acid Nutrition 0.000 description 1
- 208000006673 asthma Diseases 0.000 description 1
- 210000002421 cell wall Anatomy 0.000 description 1
- 208000013116 chronic cough Diseases 0.000 description 1
- FPAFDBFIGPHWGO-UHFFFAOYSA-N dioxosilane;oxomagnesium;hydrate Chemical compound O.[Mg]=O.[Mg]=O.[Mg]=O.O=[Si]=O.O=[Si]=O.O=[Si]=O.O=[Si]=O FPAFDBFIGPHWGO-UHFFFAOYSA-N 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 235000008434 ginseng Nutrition 0.000 description 1
- 201000001881 impotence Diseases 0.000 description 1
- 239000002917 insecticide Substances 0.000 description 1
- 239000008101 lactose Substances 0.000 description 1
- 239000000463 material Substances 0.000 description 1
- 238000004137 mechanical activation Methods 0.000 description 1
- 238000002156 mixing Methods 0.000 description 1
- 210000003463 organelle Anatomy 0.000 description 1
- 208000026435 phlegm Diseases 0.000 description 1
- 206010036596 premature ejaculation Diseases 0.000 description 1
- 235000018102 proteins Nutrition 0.000 description 1
- 102000004169 proteins and genes Human genes 0.000 description 1
- 108090000623 proteins and genes Proteins 0.000 description 1
- 230000000630 rising effect Effects 0.000 description 1
- 235000014347 soups Nutrition 0.000 description 1
- 239000008107 starch Substances 0.000 description 1
- 235000019698 starch Nutrition 0.000 description 1
- 229940098465 tincture Drugs 0.000 description 1
- 235000015961 tonic Nutrition 0.000 description 1
- 230000001256 tonic effect Effects 0.000 description 1
- 229960000716 tonics Drugs 0.000 description 1
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- Medicinal Preparation (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Abstract
The present invention belongs to the field of medicine and food, and is especially crushing method and preparation of aweto. During crushing of aweto, the polypide and the stroma are crushed separately in different conditions determined on their different structures, fiber contents and effective matter contents, and this can avoid loss of effective components in the polypide caused by lasting heating and raise product quality.
Description
Technical field
The present invention relates to the breaking method of Cordyceps and the preparation that is prepared from the Cordyceps after pulverizing, belong to medicine, food and field of health care food.
Background technology
Cordyceps Cordyceps sinensis (Berk.) Sacc. is the traditional rare Chinese medicine of China, and is equally celebrated for their achievements with Radix Ginseng, Cornu Cervi Pantotrichum, is listed as three big tonics.Cordyceps is the larva cadaveric complex of the Stroma of Clavicipitaceae plant Cordyceps fungus and host's Hepialidae insecticide Cordyceps Hepialus armorieanus Oberthur Hepialus armorcanus Oberthiir thereof etc.Be distributed in the mesophorbium, coryphiles of ground height above sea level more than 3000 meters such as Qinghai, Tibet, Sichuan, Yunnan, Guizhou, Gansu.Cordyceps has effects such as kidney-replenishing, kidney tonifying essence, tonifying the lung gas, expelling phlegm for arresting cough are relievingd asthma, lung benefiting the moon, is the key medicine of treatment chronic cough dyspnea due to deficiency, the treatment impotence due to deficiency of the kidney, and premature ejaculation is very thin also a very significant effect,
How modern application to Cordyceps is fried in shallow oil it soup or is stewed clothes, or be made as powder, pill, capsule, tablet or medicated wine.But in crushing process, how Cordyceps is directly pulverized, but because of the polypide of Cordyceps and Stroma widely different at aspects such as cell composition and structure, fiber content, active substance content, if pulverize simultaneously, then be difficult to make it to reach the breaking cellular wall level equably, promptly can not satisfy the homogeneity of grinding particle size.If satisfy the pulverizing requirement of polypide part, reasons such as Stroma is then many owing to cellulosic, cyto-architectural difference are difficult to reach the requirement of grinding particle size; If satisfy the pulverizing requirement of Stroma part, then the effective ingredient of polypide part is gone to pot or lose owing to reasons such as excessively refinement, temperature risings.
At present, the breaking method of existing Cordyceps all is that mixing polypide and Stroma are pulverized, the method for homogeneity difference and minimizing loss of effective components when still not having its pulverizing of solution.
Summary of the invention
A technical problem to be solved by this invention provides a kind of breaking method of Cordyceps, it is characterized in that: with polypide and Stroma pulverize separately.
With polypide and Stroma pulverize separately, can suitable pulverization conditions be set according to polypide and Stroma cell composition and structure, fiber content, active substance content separately, the smashing fineness that obtains suiting, make the breaking cellular wall degree meet homogeneity, reduce long-time high temperature simultaneously and pulverize, satisfy the demand of the public the Cordyceps preparation to polypide part loss of active ingredients.
The specific embodiment
The invention provides a kind of breaking method of Cordyceps: with polypide and Stroma pulverize separately.Adoptable breaking method has artificial pulverizing or mechanical activation comminution.
Polypide and Stroma smashing fineness reach 40 orders at least, can reach the requirement of pulverizing the back preparation or directly taking.Polypide and Stroma smashing fineness reach 350 orders, can make cell wall breaking; Polypide and Stroma are pulverized and are reached 500 orders, can make the most cells breaking cellular wall.Polypide and Stroma smashing fineness reach 2000 orders or thinner, can destroy organelle, and when human body was taken the Cordyceps of this smashing fineness, the stripping rapidly of effective ingredient wherein improved bioavailability.
The present invention also provide by breaking method of the present invention preparation the Cordyceps preparation, it is characterized in that: get at least a in polypide after the pulverizing, the Stroma, can not add adjuvant, be prepared from according to the preparation method of conventional pharmaceutical, food or health food; Also can add pharmacy, food or health food adjuvant or complementary composition commonly used is prepared from.
Wherein, described preparation can be oral formulations.Usually make solid preparation or liquid preparation.
Described solid preparation can be powder, pill, tablet or capsule etc.; Described liquid preparation can be oral liquid, decoct or medicated wine etc.
The advantage of breaking method of the present invention and Cordyceps preparation of the present invention is described by the following examples.
The breaking method of embodiment 1 Cordyceps of the present invention
A, letter sorting Cordyceps polypide and Stroma, pulverize separately to polypide and Stroma can cross 40 mesh sieves.
B, letter sorting Cordyceps polypide and Stroma, pulverize separately to polypide and Stroma can cross 350 mesh sieves.
C, letter sorting Cordyceps polypide and Stroma, pulverize separately to polypide and Stroma can cross 500 mesh sieves.
D, letter sorting Cordyceps polypide and Stroma, pulverize separately to polypide and Stroma can cross 1000 mesh sieves.
E, letter sorting Cordyceps polypide and Stroma, pulverize separately to polypide and Stroma can cross 1500 mesh sieves.
F, letter sorting Cordyceps polypide and Stroma, pulverize separately to polypide and Stroma can cross 2000 mesh sieves.
G, letter sorting Cordyceps polypide and Stroma, pulverize separately to polypide and Stroma can cross 2500 mesh sieves.
H, letter sorting Cordyceps polypide and Stroma, pulverize separately can be crossed 500 mesh sieves to polypide, and Stroma can be crossed 350 mesh sieves.
I, letter sorting Cordyceps polypide and Stroma, pulverize separately can be crossed 1000 mesh sieves to polypide, and Stroma can be crossed 1500 mesh sieves.
J, letter sorting Cordyceps polypide and Stroma, pulverize separately can be crossed 500 mesh sieves to polypide, and Stroma can be crossed 40 mesh sieves.
K, letter sorting Cordyceps polypide and Stroma, pulverize separately can be crossed 2000 mesh sieves to polypide, and Stroma can be crossed 350 mesh sieves.
By comparing, polypide is few than the pulverizing time that Stroma needs.If the pulverizing that the conventional pulverizing time of not sorting direct breaking method equals polypide is during the time, the Stroma of pulverizing gained is many because of fibre-bearing, and the pulverizing time is not enough, the smashing fineness that the part Stroma does not reach requirement occurs.If conventional do not sort the direct breaking method pulverizing time and equal pulverizing time of Stroma, the polypide main component is aminoacid, protein material, and the long-time high temperature that produces of pulverizing very easily destroys effective ingredient in the polypide, causes the loss of effective components in the Cordyceps.
Adopt the Cordyceps of breaking method gained of the present invention to prepare preparation, can directly use after being crushed to suitable fineness as powder, perhaps directly encapsulated or tabletting prepares becomes capsule or tablet, also can add acceptable auxiliary, as preparation capsule or tablets such as starch, lactose, Pulvis Talci, the ethanol that also can add suitable concentration is made tincture.Effective ingredient in the more existing Cordyceps preparation of preparation for preparing and get is easier to be absorbed in human body, and bioavailability is higher.
Claims (10)
1, the breaking method of Cordyceps is characterized in that: with polypide and Stroma pulverize separately.
2, the breaking method of Cordyceps according to claim 1 is characterized in that: the polypide smashing fineness reaches 40 orders at least; The Stroma smashing fineness reaches 40 orders at least.
3, the breaking method of Cordyceps according to claim 2 is characterized in that: the polypide smashing fineness reaches 350 orders at least; The Stroma smashing fineness reaches 350 orders at least.
4, the breaking method of Cordyceps according to claim 3 is characterized in that: the polypide smashing fineness reaches 500 orders at least; The Stroma smashing fineness reaches 500 orders at least.
The breaking method of 5 Cordyceps according to claim 4 is characterized in that: the polypide smashing fineness reaches 2000 orders at least; The Stroma smashing fineness reaches 2000 orders at least.
6, each described breaking method preparation of claim 1～5 and the Cordyceps preparation, it is characterized in that: get at least a in polypide after the pulverizing, the Stroma, be prepared from according to the preparation method of conventional pharmaceutical, food or health food.
7, each described breaking method preparation of claim 1～5 and the Cordyceps preparation, it is characterized in that: get at least a in polypide after the pulverizing, the Stroma, add pharmaceutically, adjuvant or complementary composition commonly used is prepared from the food or on the health food.
8, according to claim 6 or 7 described Cordyceps preparations, it is characterized in that: described preparation is an oral formulations.
9, Cordyceps preparation according to claim 8 is characterized in that: described oral formulations is solid preparation or liquid preparation.
10, Cordyceps preparation according to claim 9 is characterized in that: described solid preparation is powder, pill, tablet or capsule; Described liquid preparation is oral liquid, decoct or medicated wine.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2007100486518A CN101019898B (en) | 2007-03-16 | 2007-03-16 | Crushing method and preparation of aweto |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2007100486518A CN101019898B (en) | 2007-03-16 | 2007-03-16 | Crushing method and preparation of aweto |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN101019898A true CN101019898A (en) | 2007-08-22 |
| CN101019898B CN101019898B (en) | 2010-07-21 |
Family
ID=38707824
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN2007100486518A Active CN101019898B (en) | 2007-03-16 | 2007-03-16 | Crushing method and preparation of aweto |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN101019898B (en) |
Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102742838A (en) * | 2011-07-11 | 2012-10-24 | 张雪峰 | Preparation method of Chinese caterpillar fungus freeze-dried buccal tablet |
| CN102895651A (en) * | 2012-11-05 | 2013-01-30 | 贵州神奇集团控股有限公司 | Chinese caterpillar fungus oral preparation and preparation method thereof |
| CN103432175A (en) * | 2013-09-11 | 2013-12-11 | 大连海晏堂生物有限公司 | Quality grade classification method of cordyceps sinensis |
| CN103705544A (en) * | 2013-12-13 | 2014-04-09 | 西宁之也生物科技咨询服务有限公司 | Cordyceps sinensis(Berk.)Sacc. oral preparation and production method thereof |
| CN103705545A (en) * | 2013-12-13 | 2014-04-09 | 西宁之也生物科技咨询服务有限公司 | Cordyceps sinensis micro-powder preparation and preparation method thereof |
-
2007
- 2007-03-16 CN CN2007100486518A patent/CN101019898B/en active Active
Cited By (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102742838A (en) * | 2011-07-11 | 2012-10-24 | 张雪峰 | Preparation method of Chinese caterpillar fungus freeze-dried buccal tablet |
| CN102895651A (en) * | 2012-11-05 | 2013-01-30 | 贵州神奇集团控股有限公司 | Chinese caterpillar fungus oral preparation and preparation method thereof |
| CN102895651B (en) * | 2012-11-05 | 2015-01-14 | 贵州神奇集团控股有限公司 | Chinese caterpillar fungus oral preparation and preparation method thereof |
| CN103432175A (en) * | 2013-09-11 | 2013-12-11 | 大连海晏堂生物有限公司 | Quality grade classification method of cordyceps sinensis |
| CN103705544A (en) * | 2013-12-13 | 2014-04-09 | 西宁之也生物科技咨询服务有限公司 | Cordyceps sinensis(Berk.)Sacc. oral preparation and production method thereof |
| CN103705545A (en) * | 2013-12-13 | 2014-04-09 | 西宁之也生物科技咨询服务有限公司 | Cordyceps sinensis micro-powder preparation and preparation method thereof |
| CN103705545B (en) * | 2013-12-13 | 2017-09-15 | 青海之也科技咨询服务有限公司 | A kind of aweto micropowder preparation and preparation method thereof |
Also Published As
| Publication number | Publication date |
|---|---|
| CN101019898B (en) | 2010-07-21 |
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