CN100593417C - Chinese traditional medicine for treating gastric cancer and bone cancer - Google Patents

Chinese traditional medicine for treating gastric cancer and bone cancer Download PDF

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CN100593417C
CN100593417C CN200710017935A CN200710017935A CN100593417C CN 100593417 C CN100593417 C CN 100593417C CN 200710017935 A CN200710017935 A CN 200710017935A CN 200710017935 A CN200710017935 A CN 200710017935A CN 100593417 C CN100593417 C CN 100593417C
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radix
herba
gastric cancer
osteocarcinoma
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王化选
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Abstract

The invention discloses a Chinese pharmaceutical composition for treating gastric cancer and osteocarcinoma, which is prepared from oldenlandia, barbat skullcap, house lizard, wasp's nest, pilose asiabell root, Chinese angelica root, job's tears, chicken's gizzard-skin, haw, scutellaria root, hairy vein agrimony, root of herbaceous peony and corydalis tuber through powdering and mixing homogeneously. The medicament can be prepared into powders or capsules.

Description

A kind of Chinese medicine for the treatment of gastric cancer and osteocarcinoma
Technical field
The present invention relates to a kind of Chinese medicine, more particularly, relate to a kind of Chinese medicine for the treatment of gastric cancer and osteocarcinoma.
Background technology
At present, undertaken by the doctor trained in Western medicine means basically clinically at the treatment means of gastric cancer and osteocarcinoma both at home and abroad, its mode that adopts is operation, radiotherapy and chemotherapy basically.From final result, the relapse rate of operation, diffusion and the rate of transform are generally all more than 80%, and majority shifts in the short period after operation.Radiotherapy chemotherapy has positive meaning in the phase I of the course of disease, but over-drastic chemotherapy radiotherapy is very big to people's whole machine body, function destruction, and according to the interrelated data statistics, excessive and irrational treatment can cause about 15% patient with advanced cancer acceleration death.In view of all drawbacks of doctor trained in Western medicine, domestic showing also gropes to adopt the mode of the traditional Chinese medical science to treat gradually, and certain effect is arranged.Existing problem be, the first, the active ingredient of extracting certain Chinese medicine becomes tablet or injection, route of administration is simple and easy to do, but can not represent former Chinese medicine itself fully; The second, existing Chinese medicine preparation is only paid attention to tumor body itself, does not pay attention to integral body, break away from basic theory of tcm, thereby therapeutic effect is undesirable.
Summary of the invention
The objective of the invention is to overcome the defective that exists in the prior art, provide in a kind of can effectively the treatment, late gastric cancer and osteocarcinoma and prevent the pure Chinese medicine curing cancer drug of transfer and relapse.
Chinese medicine of the present invention selects Herba Hedyotidis Diffusae, Herba Scutellariae Barbatae, Gekko Swinhonis, Nidus Vespae, Radix Codonopsis, Radix Angelicae Sinensis to make up, make each efficacy of drugs produce synergism the said medicine combination, can heat clearing away poison, separate malignant boil, resolving the hard mass, strengthening body resistance and dispelling evil, thus reach therapeutic effect.Wherein selecting Herba Hedyotidis Diffusae, Herba Scutellariae Barbatae for use is because of this two flavors medicine energy heat clearing away, detoxifcation, detumescence.Select for use Gekko Swinhonis, Nidus Vespae to be because it can break heavily fortified point, detoxifcation, eliminating stagnation.And select ginseng for use, returning can replenishing QI and blood, help roman, wherein Radix Codonopsis is to be used for QI invigorating, Radix Angelicae Sinensis is to be used for enriching blood, invigorating blood circulation.
In order to reach better therapeutic effect, medicine of the present invention also makes up with Semen Coicis, Endothelium Corneum Gigeriae Galli, Fructus Crataegi.This is because according to modern study, and this three flavors medicine all has the effect of anti-cancer, anticancer, anticancer, and the while Semen Coicis also is used for spleen invigorating, dehumidifying; Endothelium Corneum Gigeriae Galli is used for helping digestion, eliminating stagnation; Fructus Crataegi is used for helping digestion, invigorating blood circulation.
In order to obtain optimum curative effect, the present invention can also add Radix Scutellariae, Herba Agrimoniae, the Radix Paeoniae Alba, Rhizoma Corydalis on the said medicine basis.This is because of the heat clearing away of Radix Scutellariae energy, dampness, pathogenic fire purging; The existing stable and persistent antitumaous effect of Herba Agrimoniae can also be restrained, stop blooding simultaneously; The Radix Paeoniae Alba yin fluid astringing that can nourish blood plays centralizing function, can the easing the affected liver emergency relieve the pain again; Rhizoma Corydalis is used for invigorating blood circulation, circulation of qi promoting, relieve the pain, and makes QI and blood unobstructed.The Radix Paeoniae Alba can be removed empty pain; Rhizoma Corydalis is removed real pain, and deficiency and excess is also seen to reach the purpose of " logical person is not bitterly ".
Each drug component consumption of the present invention is for all to have curative effect preferably in following ranges:
4~6 parts of Herba Hedyotidis Diffusaes, 3~5 parts of Herba Scutellariae Barbataes, 1.5~3.5 parts of Gekko Swinhoniss, 1.5~3.5 parts of Nidus Vespaes, 1~3 part of Radix Codonopsis, 1~3 part of Radix Angelicae Sinensis.
Be preferably: 5 parts of Herba Hedyotidis Diffusaes, 4 parts of Herba Scutellariae Barbataes, 2.5 parts of Gekko Swinhoniss, 2.5 parts of Nidus Vespaes, 2 parts of Radix Codonopsis, 2 parts of Radix Angelicae Sinensis.
Each amounts of components of medicine of the present invention can also be: 4~6 parts of Herba Hedyotidis Diffusaes, 3~5 parts of Herba Scutellariae Barbataes, 1.5~3.5 parts of Gekko Swinhoniss, 1.5~3.5 parts of Nidus Vespaes, 1~3 part of Radix Codonopsis, 1~3 part of Radix Angelicae Sinensis, 1~2 part of Semen Coicis, 1~2 part of Endothelium Corneum Gigeriae Galli, 1~2 part of Fructus Crataegi.
Be preferably: 5 parts of Herba Hedyotidis Diffusaes, 4 parts of Herba Scutellariae Barbataes, 2.5 parts of Gekko Swinhoniss, 2.5 parts of Nidus Vespaes, 2 parts of Radix Codonopsis, 2 parts of Radix Angelicae Sinensis, 1.5 parts of Semen Coiciss, 1.5 parts of Endothelium Corneum Gigeriae Galli, 1.5 parts of Fructus Crataegi.
The medicine of the present invention further consumption of each component is 4~6 parts of Herba Hedyotidis Diffusaes, 3~5 parts of Herba Scutellariae Barbataes, 1.5~3.5 parts of Gekko Swinhoniss, 1.5~3.5 parts of Nidus Vespaes, 1~3 part of Radix Codonopsis, 1~3 part of Radix Angelicae Sinensis, 1~2 part of Semen Coicis, 1~2 part of Endothelium Corneum Gigeriae Galli, 1~2 part of Fructus Crataegi, 0.5~1.5 part of Radix Scutellariae, 1~3 part of the Radix Paeoniae Alba, 1~3 part of Rhizoma Corydalis, 1~3 part of Herba Agrimoniae.
Be preferably: 5 parts of Herba Hedyotidis Diffusaes, 4 parts of Herba Scutellariae Barbataes, 2.5 parts of Gekko Swinhoniss, 2.5 parts of Nidus Vespaes, 2 parts of Radix Codonopsis, 2 parts of Radix Angelicae Sinensis, 1.5 parts of Semen Coiciss, 1.5 parts of Endothelium Corneum Gigeriae Galli, 1.5 parts of Fructus Crataegi, 1 part of Radix Scutellariae, 2 parts of the Radix Paeoniae Albas, 2 parts of Rhizoma Corydalis, 2 parts of Herba Agrimoniaes.
Medicine of the present invention can adopt that conventional method is prepared into any conventional oral preparations in the Chinese medicine preparation.As can with these crude drug respectively as requested big gun moxibustion pulverize mix homogeneously make powder and take after mixing it with water, also can be made into dosage forms such as capsule and take.
Medicine of the present invention has following effect:
1, intermediate gastric carcinoma, osteocarcinoma there are elimination tumor body, eliminate symptom, prevention of recurrence down to the effect of fully recovering;
2, late gastric cancer, osteocarcinoma there are time-to-live of dwindling tumor body, mitigation symptoms, prolongation patient and the life quality that improves the patient.
The specific embodiment
Come by the following examples the preparation method and the beneficial effect of medicine of the present invention are further elaborated.
1, the preparation method of medicine of the present invention and instructions of taking
Preparation method: take by weighing 5 kilograms of Herba Hedyotidis Diffusaes, 4 kilograms of Herba Scutellariae Barbataes, 2.5 kilograms of Gekko Swinhoniss, 2.5 kilograms of Nidus Vespaes, 2 kilograms of Radix Codonopsis, 2 kilograms of Radix Angelicae Sinensis, 1.5 kilograms of Semen Coiciss, 1.5 kilograms of Endothelium Corneum Gigeriae Galli, 1.5 kilograms of Fructus Crataegi, 1 kilogram of Radix Scutellariae, 2 kilograms of the Radix Paeoniae Albas, 2 kilograms of Rhizoma Corydalis, 2 kilograms of Herba Agrimoniaes, above-mentioned each component medicine material is dried, cleans, the big gun moxibustion, removes foreign material, chopping back mix homogeneously, make zero capsule after grinding into powder, every content 0.35g.
Instructions of taking:
Consumption: 15~20 of adult's consumptions every day, the child is cut down according to the circumstance according to the age consumption.
Usage: adult every day 3 times, each 5~6.
2, the clinical observation of the Chinese medicine of Drug therapy gastric cancer of the present invention and osteocarcinoma
1) physical data
Treat patient's 35 examples altogether, wherein male 20 examples, women 15 examples, the age was at 45~70 years old.Above-mentioned patient all is diagnosed as terminal cancer by CT and check pathological section.
2) diagnostic criteria
Patients with gastric cancer: nausea and vomiting, the time have the companion to spit blood, do not eat, become thin, weak, stomach pain general or violent, can touch and see enclosed mass, black stool, spirit is poor.
Osteocarcinoma patient: after the operation that suffers from breast cancer, promptly shifting soon is osteocarcinoma, and upper limb or lower limb have an intense pain.Can not walk, stiff, have also with pulmonary carcinoma, chest pain, cough, abundant expectoration, breathe hard, become thin, weak, spirit poor, anorexia, the stool more than not smooth.
Patient with esophageal carcinoma: the pharynx thing is unfavorable, noodles, and staple food, steamed bun can't be swallowed.Can only drink suitable liquid and water, the time have vomiting, the time retrosternal pain arranged, spirit is poor, not smooth more than the stool, it is weak to become thin etc.
Peritoneum rear wall malignant tumor: be renal carcinoma operation back or the uterus carcinoma recurrence after operation that have shift, and lump is huge, sharp ache, poor appetite, sleep poor, spiritual poor.Two is just flat.
3) Therapeutic Method
Oral medicament capsule of the present invention, every day 3 times, each 5-6 grain.If stomach distension pain, the time nauseating tending to vomit is arranged, stool impassable patient, the spleen invigorating invigorating middle warmer that at every turn the adds autogamy capsule 3-4 grain that helps digestion.If esophagus is not smooth, the unfavorable person of pharynx thing can pour the medicine in the capsule in the container into, adds an amount of eliminating cold for resuscitation water and mixes the back clothes thoroughly, and drug effect is unaffected.
4) efficacy assessment standard
Produce effects: pain disappears, and the tumor body is eliminated or obviously dwindled, and appetite is normal, and is energetic, and stable disease is recovered work or physical labor normally.
Take a turn for the better: pain disappears, and the tumor body obviously dwindles, and appetite is normal, spirit still can, Shi Youxiao still need treat repeatedly, treats after 10~15 days, can recover normal.
Effectively: pain relief, appetite increases, and spirit is recovered to some extent, and tumor is dwindled or is not made progress, and the state of an illness can be stablized a stage.
Invalid: symptom does not alleviate, and the state of an illness continues development.
5) therapeutic outcome (see the following form 1 and table 2)
Table 1 is observation of curative effect after treating
Figure C20071001793500061
Table 2 sign after treating is improved situation
Symptom Have an intense pain The tumor body increases Be off one's feed Lassitude
Before the treatment (example) 23 25 30 35
Treatment back (example) 2 1 1 2
Total effective rate (%) 91% 96% 96.7% 94.3%
In a word, with the above-mentioned malignant tumor patient of Drug therapy of the present invention, produce effects 11 examples, 22 examples that take a turn for the better, invalid 2 examples, obvious effective rate 31.4%, improvement rate 62.8%, effective percentage 94.3%, inefficiency 5.7%.
Up to the present, concrete typical case used in the present invention has:
Case 1: the week certain, the man, 68 years old, be diagnosed as gastric cancer (poorly differentiated adenocarcinoma) by Weinan, Shaanxi Province Pathology Deparment of central hospital in June, 2000, belong to late period, fail to respond to any medical treatment, promptly obey Chinese medicinal capsule of the present invention with other method, cooperate the spleen invigorating invigorating middle warmer capsule that helps digestion, every day 3 times, each each 3~4.After the medication 3 days, patient's stomachache, the tending to vomit of feeling sick, haematemesis, aphagia shape alleviate gradually.Continuous use March, symptomatology disappears, and tumor does not exist, and all are as the normal person.Suffering from heart infarction up in June, 2006 passes away.
Case 2: the hole, the woman, 50 years old, be diagnosed as breast carcinoma at the beginning of 2004, to perform an operation immediately, half a year, rear right-leg had an intense pain, and through being CT and case control is diagnosed as osteocarcinoma, promptly carried out radiotherapy, chemotherapy result is invalid.Poor, the anorexia of patient's spirit, right lower limb has an intense pain, and is stiff, and it is poor to sleep.After take Chinese medicinal capsule of the present invention, every day 3 times, each 5~6.After 5 days, pain alleviates gradually, and spirit takes a turn for the better gradually, and appetite is normal, dormancy can, can also descend ground movable.Continuous use March, spirit still can, the emotion optimism, appetite is normal, enclosed mass is contracted to 2cm * 1.5cm by original 4cm * 3cm and the deliquescing of tumor body diminishes, pain not, all are normal.
Case 3: Zhao, the man, 65 years old, to suffer from surplus the gastropathy 10 year, be diagnosed as gastric cancer (well-differentiated adenocarcinoma) late period by the attached First Academy in Shanghai Communications University, Xi'an section pathologic finding in June, 2005, needs immediate surgery.Back family members because it is older, a little less than the health, refusal is performed an operation.Patient's nausea and vomiting, the time with the blood streak, do not eat, the side of taking back in the stomach has an intense pain, enclosed mass 4.5cm * 3cm, depressed, spirit is poor, stool is smooth, dormancy is poor.After take Chinese medicinal capsule of the present invention, and join the homemade spleen invigorating invigorating middle warmer capsule that helps digestion, every day 3 times, each 6 of Chinese medicinal capsule of the present invention, spleen invigorating invigorating middle warmer each 4 of the capsule that helps digestion.After the medication 5 days, nausea and vomiting stops, and pain alleviates gradually, and diet increases, and spiritual emotion takes a turn for the better.After taking March continuously, in high spirits, appetite is normal, pain not, dormancy can, it is unimpeded to defecate, enclosed mass is contracted to 2cm * 1.5cm, now living, all are normal.
Case 4: Zhang, the woman 52 years old, is diagnosed as operation immediately after the breast carcinoma in May, 2004.Spring in 2006 was diagnosed as pulmonary carcinoma, osteocarcinoma by Weinan City central hospital, belong to shift late period, carried out two courses of treatment of radiotherapy, chemotherapy, invalid leaving hospital immediately in hospital.Patient's pale complexion, faint low voice, cough is breathed hard, and the left side chest and back pain is violent, and the right upper extremity sharp ache is stiff, does not take food, and it is poor to sleep, and it is not smooth, depressed to defecate.After take Chinese medicinal capsule of the present invention, every day 3 times, each 5.Take medicine after 1 week, diet increases, free movement of the bowels, and the cough chest and back pain alleviates.Continuous use is after January, and right upper extremity (osteocarcinoma) pain disappears, can be movable, receive can, dormancy can, spiritual emotion takes a turn for the better, having the cough symptom of breathing hard only and occuring now and then, the time intermittent use arranged.
Case 5: go into business certain, man, 58 years old.All be diagnosed as the esophageal carcinoma by Xi'an tumour hospital, two families of Weinan City central hospital at the beginning of 1997.After the radiotherapy of Xi'an tumour hospital, there is not effect, cause that on the contrary nervi trigeminus has an intense pain, bigger than normal because of tumor, anorexia noodles, steamed bread can only be drunk gruel, boiled water, spiritual extreme difference, depressed, it is poor to sleep.After curing trigeminal neuralgia with 8 doses of other Chinese medicine decoction earlier, take Chinese medicinal capsule of the present invention immediately,, promptly take out medicated powder and pour in the container, add an amount of eliminating cold for resuscitation water, take every day 3 times, each 6 after mixing thoroughly because of the difficulty of swallowing.After taking 10 days continuously, conscious esophageal pharynx thing is unimpeded gradually.Behind the continuous use 3 months, the esophagus diseased region is unobstructed fully, and corpus carcinosus is eliminated, and as before the disease, noodles, steamed bread are helped yourself, and have not had any discomfort.In high spirits, appetite is normal.Physically strong, be the essential labour person in the field.Continuously survival is 10 years, up in by the end of December, 2006, because of multiple other disease such as heart failure, cerebral infarction and the death of one's spouse pain pass away.

Claims (2)

1. a Chinese medicine for the treatment of gastric cancer and osteocarcinoma is characterized in that it is made up of following components in weight percentage: 4~6 parts of Herba Hedyotidis Diffusaes, 3~5 parts of Herba Scutellariae Barbataes, 1.5~3.5 parts of Gekko Swinhoniss, 1.5~3.5 parts of Nidus Vespaes, 1~3 part of Radix Codonopsis, 1~3 part of Radix Angelicae Sinensis, 1~2 part of Semen Coicis, 1~2 part of Endothelium Corneum Gigeriae Galli, 1~2 part of Fructus Crataegi, 0.5~1.5 part of Radix Scutellariae, 1~3 part of the Radix Paeoniae Alba, 1~3 part of Rhizoma Corydalis, 1~3 part of Herba Agrimoniae.
2. the Chinese medicine of treatment gastric cancer according to claim 1 and osteocarcinoma is characterized in that, 5 parts of Herba Hedyotidis Diffusaes, 4 parts of Herba Scutellariae Barbataes, 2.5 parts of Gekko Swinhoniss, 2.5 parts of Nidus Vespaes, 2 parts of Radix Codonopsis, 2 parts of Radix Angelicae Sinensis, 1.5 parts of Semen Coiciss, 1.5 parts of Endothelium Corneum Gigeriae Galli, 1.5 parts of Fructus Crataegi, 1 part of Radix Scutellariae, 2 parts of the Radix Paeoniae Albas, 2 parts of Rhizoma Corydalis, 2 parts of Herba Agrimoniaes.
CN200710017935A 2007-05-25 2007-05-25 Chinese traditional medicine for treating gastric cancer and bone cancer Expired - Fee Related CN100593417C (en)

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