CN100571766C - A kind of Chinese medicine medicine for the treatment of alcohol dependence disease - Google Patents
A kind of Chinese medicine medicine for the treatment of alcohol dependence disease Download PDFInfo
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Abstract
The invention discloses a kind of Chinese medicine medicine for the treatment of alcohol dependence disease, it is the decoction of being made by the following weight proportion raw material: Bulbus Lilii 30, Radix Curcumae 15, Fructus Schisandrae Chinensis 10, Fructus Mori 30, Fructus Aurantii Immaturus 12, Massa Medicata Fermentata 30, Radix Polygalae 12, Os Draconis 30, Radix Salviae Miltiorrhizae 15, Concha Ostreae 30, Ramulus Uncariae Cum Uncis 10, Fructus Gardeniae 10, Radix Glycyrrhizae 10, Fructus Alpiniae Oxyphyllae 30, Rhizoma Alismatis 15, Concha Margaritifera 30, Rhizoma Acori Graminei 15, Semen Glycine Germinatum 50; The present invention selects the natural Chinese medicines raw material for use, and each component meets pharmaceutical control law regulation, utilizes the comprehensive function of the Chinese medicine of respectively distinguishing the flavor of, and alcohol dependence disease is had the effect of healing, does not have chemical sweeting agent, and is nontoxic to human body; The present invention distinguishes the flavor of little sweet, no bitterness sense, taking convenience.Select case through clinical observation for many years, ten days is a course of treatment, day clothes 2 times, and each 50ml, nearly 1000 examples that heal the sick, health returns to one's perfect health to effectively, and total effective rate is 99%.Medicine of the present invention can be widely used in the clinical treatment alcohol dependence disease.
Description
Technical field
The invention belongs to the Chinese medicine technical field of pharmaceuticals, be specifically related to a kind of Chinese medicine medicine for the treatment of alcohol dependence disease.
Background technology
The alcohol dependence disease of drinking for a long time and causing has become world today's serious social concern.Alcohol dependence disease is owing to the caused a kind of special mental disease of drinking repeatedly, and patient has the sense that forces craving for constantly need drink of pair wine, and sustainable or interruption occurs, if stop to drink the psychological and physiology withdrawal symptom of then appearance.A series of brain pathological changes also can occur, as brain tissue inflammation, positions such as cerebrovascular sclerosis, ganglion basal and central gray substance are hemorrhage, are also shown in neuron fatty infiltration, demyelination degeneration and brain atrophy in various degree etc.Ethanol is also very outstanding to the infringement of liver, and long-term heavy drinking often causes alcoholism hepatitis, fatty liver and liver cirrhosis.In addition, polyneuritis, myocarditis, gastritis and gastric ulcer and acute and chronic pancreatitis etc. are also relevant with excessive drinking.Its cause of disease and pathogenesis are very complicated, are commonly considered as that individual biological factor and social environmental factor influence each other, coefficient result, specifically are expressed as follows:
1, the inherited genetic factors survey data confirms, the familial aggregation of alcohol intoxication is very obvious.The relative risk that the alcoholic children suffer from alcohol intoxication is 3～4 times of normal control group children.Parents' alcoholism is serious more, and its children suffer from sick risk also big more.
2, biochemical unusual ethanol can cause the unusual of some regional dopamine (DA) systemic-function of brain.Result of study shows, gives laboratory animal DA antagonist and can cause its increase of being addicted to drink, and chemical damage DA neuron also can be strengthened the wine behavior of looking for of animal.Above-mentioned research prompting laboratory animal need be absorbed the insufficiency of function of ethanol with compensatory DA.Other has the research report, and it is relevant with 5 one hydroxytryptamines (5-HT) system exception to be addicted to drink.Be addicted to drink brain district 5 one hydroxytryptamines (5-HT) such as Mus cortex of frontal lobe, striatum and Hippocampus and metabolite 5 one hydroxyindole acetic acids (5-HIAA) content thereof than the remarkable decline of matched group; The immunostaining inspection Mus 5-HT neuron number of finding to be addicted to drink reduces, and causes that thus 5HT1A and 5-HT3 receptor number compensatory increase.Other discover the human release that ethanol causes endogenous Opium material afterwards of taking in.
Social environmental factor previously study the variety of problems of prompting society, family and economic aspect and mental disorder that ethanol causes in close relations.All once attempted to alleviate the anxiety and the anxiety that stress cause before many patient's diseases, thereby impel drinking behavior to continually strengthen by drinking.Sociocultural factor is also relevant with the generation of ethanol caused by mental disorder.
Alcohol dependence has following clinical characters: 1. to craving for of drinking, uncontrollable; 2. the fixed pattern of drinking, patient drinks in must be at a fixed time and ignores occasion, to avoid or to alleviate withdrawal symptom; 3. drinking has become all active centers, so that obviously influence work, family life and doings; 4. toleration increases gradually, and patient obtains the effect that the initial stage of drinking reaches, and perhaps prevents the generation of physiological withdrawal symptom and needs constantly to increase drinking amount; 5. withdrawal symptom occurs repeatedly, if patient reduces capacity for liquor or prolongation is drunk at interval, promptly causes the interior alcohol concentration decline of body and withdrawal symptom occurs that modal symptom is that hands, foot, extremity and trunk tremble, ataxia, and the emotion irritability easily has startle reaction; Be also shown in hyperhidrosis, nausea and vomiting.If in time drink, above-mentioned withdrawal symptom can rapidly disappear.Because of the nighttime sleep time longer, the blood plasma alcohol concentration descends obviously, so the withdrawal symptom pilosity is born in early morning.So most patients all drink in the morning, so as to alleviating the discomfort that withdrawal symptom causes.This phenomenon is called " drink in morning ", and the diagnosis of dependence syndrome is had important meaning.Patients with alcohol dependence is after giving up after a while as drink again and then more promptly reproduce the symptomatology that relies on.Tromomania, hallucinosis, paranoea, alcohol intoxication encephalopathy (HIE), dysthymic disorder etc. also can appear in weight person.
The comprehensive therapy of many at present employings, its basic step is:
1. alleviating alcohol addiction guards against that to spill be the committed step that can treatment successful.Grasp the progress of alleviating alcohol addiction clinically according to the order of severity of patient's alcohol dependence and poisoning flexibly, avoid occurring serious withdrawal symptom.
2. Drug therapy does not still have sophisticated Temperance medicine at present.Though naloxone and naltrexone are in clinic trial, using as routine clinical still need further stockpile.The Temperance medicine that acts on norepinephrine energy and serotonergic system also is in the development stage.At anxiety and tense and the insomnia that the patient occurs, available antianxiety drugs, anti symptom treatment such as diazepam, clonazepam are because said medicine all can cause dependence, so only suitable short-term is used.For the restless tangible patient of excitement, can low dose give chlorpromazine or haloperidol intramuscular injection or oral medication.But said medicine is Western medicine, has headache, giddy, xerostomia, feels sick, vomiting, constipation, diarrhoea, blurred vision, dysuria, urine retention, abnormal liver function, side effect such as anaphylaxis, sexual dysfunction can occur with tachycardia, postural hypotension, electrocardiographic abnormality, minority.3. psychotherapy's clinical practice proves, the behavior therapy has certain effect to helping patient's alleviating alcohol addiction.Alleviating alcohol addiction sulfur is the metabolic medicine of a kind of blocking-up alcohol oxidation, can cause acetaldehyde to build up in vivo.Patient is as drinking at period in a medicine, can produce that acetaldehyde causes feel sick, headache, anxiety, uncomfortable in chest and heart rate quickening etc.This medicine has certain toxicity, can not life-time service, be advisable in general 3～5 days.The common adverse reactions of alleviating alcohol addiction sulfur is: anxiety and dying sense, and blurring of vision, respiratory distress, face and cervical region are crimson, headache, hypertension or decline are felt sick and vomiting, and posture is fainted, perspires, tachycardia, thirsty, dizzy.Severe reaction is: stupor, shock is fainted from fear, ECG change (the T ripple is low flat, and the ST section descends, and QT prolongs).Through above-mentioned treatment, still have the patient of many alcohol dependences to give up after heavy drink, be difficult to keep long-term alleviating alcohol addiction, then can reproduce original dependent status in the short period of time as drinking again.
Summary of the invention
The purpose of this invention is to provide a kind for the treatment of both the principal and secondary aspects of a disease, have no side effect, the Chinese medicine medicine of cheap treatment alcohol dependence disease.
Solution of the present invention is based on understanding and the Therapeutic Principle of motherland's medical science to the pathogeny and the human body immunity improving power of alcohol dependence, with reference to ancient, modern pharmacological research achievement, from motherland's medical treasure-house, filtering out adjusting equilibrium between yin and yang and the inclined to one side Sheng of internal organs declines partially, recover homeostatic natural Chinese medicine, by the theory of Chinese medical science prescription, skim the cream off milk, make its performance promote that yang blood and qi is regulated in the human body, vital organs of the human body twelve channels and collaterals balance, stabilizing the emotions, strengthen self-confidence, alcohol dependence disease is had the effect of healing.
Medicine of the present invention is made (consumption is a weight portion) by following component:
Bulbus Lilii 30 Radix Curcumaes 15 Fructus Schisandrae Chinensis 10 Fructus Mori 30 Fructus Aurantii Immaturuss 12 Massa Medicata Fermentata 30 Radix Polygalaes 12
Os Draconis 30 Radix Salviae Miltiorrhizaes 15 Concha Ostreaes 30 Ramulus Uncariae Cum Uncis 10 Fructus Gardeniaes 10 Radix Glycyrrhizaes 10 Fructus Alpiniae Oxyphyllae 30 Rhizoma Alismatis 15
Concha Margaritifera 30 Rhizoma Acori Graminei 15 Semen Glycine Germinatums 50
Above-mentioned each component is made Chinese medicine medicine decoction according to a conventional method, finishes by following step successively:
1) decoct: above-mentioned all medicines are put into marmite or rustless steel pressure cooker, add hydrology fire by 1: 2 of medicine total amount and decoct, boiled back 20 minutes, medicinal liquid is leached, 1: 1 by the medicine total amount adds the fiery decoction of the hydrology again, boils back 20 minutes, and medicinal liquid is leached;
2) bottling: seal in the disinfectant bottle in advance with packing into behind twice filtrate mixing;
3) sterilization: the medicinal liquid bottle is put into pressure cooker sterilization 20 minutes, promptly get Chinese medicine medicine decoction of the present invention.
Chinese medicine medicine decoction of the present invention is named and is " alleviating alcohol addiction drink ".
Bulbus Lilii in the medicine of the present invention has and strengthens immune function of human body, has calmness and hypnotic effect, Bulbus Lilii to contain abundant colchicine, can be used for show effect arthralgic auxiliary treatment and have functions such as resisting fatigue, anti-stress, protection gastric mucosa of gout; Radix Curcumae, nature and flavor suffering, hardship, cold, return liver, gallbladder, heart channel, the effect on hyperlipemia of alleviating is arranged, and can significantly promote bile secretion and drainage, and can suppress to exist the most of microorganism in the what gallbladder, analgesic activity is arranged, hepar damnification there is protective effect, has regulating qi to disperse stagnation, heart fire-clearing upset-relieving, promoting the function of the gallbladder to alleviate jaundice, the removing heat from blood effect cures mainly the amenorrhea dysmenorrhea, distending pain in the chest and hypochondrium, gastral cavity ventral spine pain, calentura coma, epilepsy unconsciousness due to blockage of phlegm, jaundice due to damp-heat, heat in blood is told nosebleed, all diseases of women's vicarious menstruation; Fructus Schisandrae Chinensis, nature and flavor acid, temperature are gone into lung, kidney channel, have to astringe the lung, nourishing kidney, promote the production of body fluid, receive the effect of antiperspirant, arresting seminal emission; Fructus Mori, sweet in the mouth acid, cold nature, go into the heart, liver, kidney channel, be strengthening by means of tonics, the good fruit of the heart nourishing and intellengence improving, have effects such as the YIN nourishing of enriching blood, promoting the production of body fluid to quench thirst, intestine moistening be dry, cure mainly deficiency of YIN-blood and disease such as having a dizzy spell of causing, tinnitus cardiopalmus, irritated insomnia, soreness of the waist and knees, early whitening of beard and hair, the xerostomia of quenching one's thirst, constipation with dry stool; Fructus Aurantii Immaturus, cold nature, bitter in the mouth, suffering, acid have the diffusing painful abdominal mass of reducing phlegm, the effect of dispelling the stagnated QI removing food stagnancy; Massa Medicata Fermentata has invigorating the spleen and regulating the stomach, a effect in transferring of helping digestion, and cures mainly the hard disease such as long-pending of retention of food and drink, feeling of stuffiness in chest abdominal distention, vomiting dysentery, postnatal blood stasis stomachache, children's's enlarged abdomen; Radix Polygalae, nature and flavor hardship, suffering, tepor, GUIXIN, kidney, lung meridian, have mind tranquilizing and the heart calming, eliminate the phlegm have one's ideas straightened out, the effect of dissipation carbuncle, cure mainly that palpitation with fear is forgetful, cards such as insomnia and dreamful sleep, staring spells, epilepsy are gone mad, cough with copious phlegm, skin sore, breast swell and pain; Rhizoma Acori Graminei, have have one's ideas straightened out, eliminating phlegm, the pharmacological action of regulating the flow of vital energy, invigorate blood circulation, loosing wind, drying, cure mainly diseases such as epilepsy, syncope due to accumulation of phlegm, calentura coma, forgetful, deafness with qi stagnation, ambition unhappiness, stomachache, stomachache, anemofrigid-damp arthralgia, swollen ulcer drug, traumatic injury; Os Draconis have the effect of tranquillizing the mind by relieving convulsion, arresting sweating controlling nocturnal emission with astringent drugs, hemostasis astringing intestine to stop diarrhea, promoting tissue regeneration and ulcer healing, cure mainly that infantile convulsion is demented, palpitation with a distress feeling is forgetful, insomnia and dreamful sleep, spontaneous sweating, seminal emission stranguria with turbid discharge, tell that nosebleed is had blood in stool, bleeding not during menses, dysentery proctoptosis, ulcer do not close up all cards for a long time; Radix Salviae Miltiorrhizae, the nature and flavor hardship, be slightly cold, GUIXIN, Liver Channel, the energy coronary artery dilator, increase coronary flow, improve core ischemia, infarction and cardiac function, adjust the rhythm of the heart, and can expand peripheral blood vessel, microcirculation improvement, anticoagulant is arranged, promote fibrinolytic, anticoagulant, suppress thrombotic effect, the energy blood fat reducing, can suppress or alleviate hepatocellular degeneration, necrosis and inflammatory reaction, promote liver cell regeneration, and anti-fibrosis effect arranged, can improve the hypoxia-bearing capability of body, can promote the reparation of tissue, quicken the healing of fracture, can shorten erythrocyte and hemoglobin convalescent period, make ceticulocytosis, various bacteria and tubercule bacillus are had inhibition, the effect that suppresses nervus centralis is arranged, also has enhance immunity in addition, blood sugar lowering and antitumor action have promoting blood flow to regulate menstruation, stasis-dispelling and pain-killing, the removing heat from blood eliminating carbuncle, the clear away heart-fire effect of relieving restlessness cures mainly month through uncomfortable, amenorrhea, dysmenorrhea, puerperal stasis of blood pain lumps in the chest and abdomen, breast ventral spine pain, rheumatic arthralgia, the skin infection carbuncle, the calentura coma, palpitation and insomnia, liver cirrhosis, the all diseases of coronary heart disease; It is wet, cool that Concha Ostreae, nature and flavor become, and goes into liver, kidney channel, has yin fluid astringing, YANG hyperactivity suppressing, hidroschesis, arresting seminal emission, reduces phlegm, the effect of softening the hard mass, cards such as the insomnia that is used to palpitate with fear, vertigo and tinnitus, tuberculous lymphadenitis, abdominal mass mass in the abdomen, spontaneous sweating, seminal emission metrorrhagia and leukorrhagia, stomachache pantothenic acid; Ramulus Uncariae Cum Uncis has the effect of endogenous wind stopping relieving convulsion, heat clearing away suppressing the hyperactive liver, cures mainly cards such as liver-wind stirring up internally, headache, dizzy, infantile convulsion tic, pregnant eclamposia, the nocturnal fretfulness in infants, hypertension; Fructus Alpiniae Oxyphyllae, nature and flavor suffering, temperature are returned kidney, spleen channel, have warming the kidney controlling nocturnal emission with astringent drugs reducing urination, the warming spleen and stopping diarrha effect of taking the photograph saliva, cure mainly that enuresis due to deficiency of the kidney, frequent micturition, seminal emission nebulousurine, spleen-cold syndrome are had loose bowels, cards such as cold type of pain, mouthful excessive saliva in the abdomen; Rhizoma Alismatis, nature and flavor are sweet, cold, go into kidney, urinary bladder channel, and the function that have diuretic, eliminating dampness by diuresis, expels the heat-evil cures mainly cards such as dysuria, edema distension, vomiting, dysentery, phlegm retention, beriberi, gonorrhea, hematuria; Concha Margaritifera is returned liver, heart channel, and suppressing the hyperactive liver and subsiding YANG, liver heat removing and eyesight improving are mainly used in cards such as headache due to deficiecny of liver-YIN, the excessive rising of liver-YANG, dizzy, tinnitus, agitation, insomnia.Fructus Gardeniae, bitter in the mouth, cold in nature, GUIXIN, liver, lung, stomach warp have the effect of pathogenic fire purging relieving restlessness, clearing away heat-damp and promoting diuresis, removing pathogenic heat from blood and toxic substance from the body, reducing swelling and alleviating pain, are mainly used in treatment calentura dysphoria with smothery sensation, jaundice due to damp-heat, heat in blood and tell diseases such as nosebleed, sore swollen toxin, traumatic injury; Radix Glycyrrhizae, nature and flavor are sweet, flat, GUIXIN, lung, spleen, stomach warp, effect with QI invigorating invigorating middle warmer, heat-clearing and toxic substances removing, expelling phlegm for arresting cough, relieving spasm to stop pain, mediation property of medicine cures mainly deficiency-weakness of spleen-QI, fatigue and weakness, shortness of breath and palpitation, cough with copious phlegm, gastral cavity abdomen and extremity contraction anxious pain, pathopyretic ulcer, laryngopharynx swelling and pain, medicine and alimentary toxicosis, the mitigation medicine is strong with toxicity etc.; Semen Glycine Germinatum, nature and flavor are sweet, flat, go into spleen, stomach warp, have the removing summer-heat pathogenic factor in the exterior, divide the effect of dampness removing medicine of a warm nature reason, be used for hygropyrexia from the beginning of, damp and hotly do not change, cards such as antiperspirant is few, the feeling of stuffiness in chest, edema distension, dysuria, arthralgia chiefly caused by damp pathogen, clonic spasm of the muscle, arthralgia with restlessness.Above-mentioned all medicines have specially good effect through reasonable compatibility to alcohol dependence disease.
The clinical use result of medicine decoction of the present invention " alleviating alcohol addiction drink " shows that following advantage is arranged:
1, the present invention selects the natural Chinese medicines raw material for use, and each component meets pharmaceutical control law regulation, utilizes the comprehensive function of the Chinese medicine of respectively distinguishing the flavor of, and alcohol dependence disease is had the effect of healing, does not have chemical sweeting agent, and is nontoxic to human body.
2, the present invention distinguish the flavor of little sweet, no bitterness sense, taking convenience.
For showing the curative effect of Chinese medicine medicine decoction of the present invention " alleviating alcohol addiction drink ", the present invention selects case through clinical observation for many years, and ten days is a course of treatment, day clothes 2 times, and each 50ml, nearly 1000 examples that heal the sick, health returns to one's perfect health to effectively, and total effective rate is 99%.
Model case is as follows:
1, poplar XX, man, 46 years old, cadre.Custom was drunk 18 years, frequently drank, flew into a rage 3 years.The patient began to drink before 18 years, and just amount is few, can control, and does not influence work, served as the chief of office afterwards owing to job demand, and all will receive every day, drinks Chinese liquor twice, about at every turn 3-4 two like this every day at least.The nearly 3 years number of times showed increased of drinking, every day Chinese liquor more than 1 jin, oneself can not be controlled, otherwise hand tremor, perspires, nervous.Therefore cellar is everywhere perhaps taken wine with oneself, and is had a strong impact on work, does not stint various means for obtaining wine, becomes gradually to the irresponsibility of working, and relatives' care is not cared a snap and easily flown into a rage.Once arrived certain section hospital diagnosis alcohol dependence, gave alleviating alcohol addiction, psychotropic therapy, but allow patient be difficult to bear drug withdrawal because of side effect such as drowsiness, nauseating, xerostomias, drink once again, come my institute's diagnosis and treatment, we allow it take " alleviating alcohol addiction drink ", twice of every day, symptom begins to alleviate after 2 courses of treatment, self-control is strong, thoroughly recovery from illness after March, and it is normal that liver transaminase recovers, follow up a case by regular visits to thoroughly alleviating alcohol addiction in 3 years, do not drink again again.
2, hole XX, man, 40 years old, workman.Because of habitual consumption of alcohol 19 years, frequent heavy drinking 6 years and come institute to seek medical advice.Patient and working before 19 years, single living at that time is with the colleague partner that buys wine, do not influence work when beginning to drink, the nearly 6 years number of times showed increased of drinking are not drunk at heart and are felt bad, and performance is on tenterhooks, have no heart for work, so drink every day several times, every day Chinese liquor about 1.5 jin, develop gradually and just drink after rising morning, do not drink hand tremor, just bottle is carried for this reason, drunk at any time, because excessive drinking is normal and wife quarrels, so that divorce, still incompatibility after remarried, in the face of relatives' cold and detached and discrimination, the self-induction heart is felt ashamed and regretful, take the Chinese and western drugs alleviating alcohol addiction in hospital and repeatedly do not become, liver power checking shows that the transaminase raises.We give quiet clonazepam treatment 10 days, but because of the walking shakiness appears in the toxic and side effects of clonazepam, the stopped treatment of having to, at this moment we give system and take " alleviating alcohol addiction drink ", twice of every day, after serveing on 6 courses of treatment, removed the strong serious hope of patient to ethanol, the liver power checking transaminase recovers normal, continue the half a year of taking medicine, stable disease, thoroughly alleviating alcohol addiction is not drunk so far more again.
3, Xu XX, man, 49 years old, government functionary.The patient makes friends wide, and friend is numerous, hurries back and forth every day because of job demand and shuttles back and forth in all kinds of wine field.Beginning wife also sympathize with and love him very much, can but find his oneself be in also stealthily drinking afterwards gradually, in addition get up in the morning also will drink it several glasss.To pothouse of a few family is arranged the dormitory, come home from work every day from his unit, and he one through the public house in front of the door just moves step.In order to waltz through the public house, he gives oneself regulation, and every family only drinks one or two, but the self-control of finally failing.His personality also becomes unexpectedly at leisure, and is selfish and irascible, and to the sense of responsibility of family seldom, behavioral standard also descends, and as untidy, lie etc., healthyly also go fromes bad to worse, and liver power checking shows that the transaminase raises, and the one family is much troubled for this reason.The household sees that he becomes inconceivable, just sends him here treatment.After diagnosing, the patient is typical alcohol dependence.A little less than considering that patient's body constitution, Electrocardioscopy before the treatment exists the T ripple unusual, if use western medicine, has the risk that meets accident, thereby we allow it take " alleviating alcohol addiction drink " treatment, take medicine after 2 courses of treatment, withdrawal symptom disappears, and rehabilitation as before after 2 months, check transaminase and electrocardiogram have recovered normal, hold on and take medicine 1 year, stable disease is not drunk again again.
4, military XX, man, 46 years old, divorce, individuality.Institute seeks medical advice over 20 years because of being addicted to drink.The patient does not begin insomnia smoothly because of love before 20 years, often drown one's sorrows in liquor, drunk at leisure into he the life whole, at night also carry bottle and drink several times, first thing of getting up inferior morning drunk exactly, and dietary amount reduces, often with wine for meal, it is not all right to know that obviously normal this goes down, but can not control exactly, and day drink Chinese liquor is more than 1 jin.When stopping drinking, will occur yawn, nervous, perspiration, vexed, have a stomach-ache, withdrawal symptom such as bone myalgia.Patient's alleviating alcohol addiction first quarter moon voluntarily of once being in is because of craving for of muscle, skeleton and psychology, so drink again once again.About 2 jin of the highest in the recent period capacity for liquor every days, wife's also impenitence of for this reason divorcing with it, health is also day by day become thin.Be admitted to hospital and the 1st week adopted stable class medicine and Supporting Therapy, withdrawal symptom disappears.A little less than considering that patient's body constitution, Electrocardioscopy before the treatment exists the T ripple unusual, if the use western medicine has the risk that meets accident, thereby we allow it take " alleviating alcohol addiction drink " treatment, take medicine 2 courses of treatment, body constitution is gradually good, and sleep improves, and drug craving almost disappears, call oneself " some drinking habits have not had " yet, be discharged from hospitals upon recovery after 2 months.Followed up a case by regular visits to 2 years, and do not drink again again.
5, king XX, man, 39 years old, workman.Be addicted to drink 7 years, and drink 1 jin of Chinese liquor every day, and capacity for liquor be cumulative.Two weeks comes cisco unity malfunction, and it is poor to sleep, and vexed not peaceful, hands shakes out antiperspirant, and the back above-mentioned symptom of drinking disappears, and borrows money to buy wine and drink steathily for this reason, and what the household advised does not listen, and to family's no responsibility sense, work efficiency obviously reduces, and is then sent here institute by the household and seeks medical advice.Diagnosis " alcohol dependence ", liver power checking shows that the transaminase raises.We take " alleviating alcohol addiction drink " treatment, and cooperate the cognitive psychological treatment after 4 months, above transference cure, and it is normal that the liver power checking transaminase recovers.Followed up a case by regular visits to 2 years, stable disease does not have multiple drink.。
6, open X, man, 50 years old, workman, divorce.Because of the 16 years repeatedly hospitalization of losing control of of frequently drinking, fly into a rage, all diagnosis " alcohol dependence ".Jin Yin unit does not arrange work to it, allows it retire, and its son does not show filal obedience in addition, and the patient is angry often, show downheartedly, drinks sorrow down all day, causes disease relapse to come institute to treat once more.After diazepam class medicine and the treatment of low dose of antipsychotic drug, mental symptom and somatization are clearly better, but mental status is not good, often betray the thought that pessimism is given up as hopeless, give oral " alleviating alcohol addiction drink " treatment, the treatment January after, the state of an illness is gradually stable, follow up a case by regular visits to 1 year patient and do not drink again again, it is good that social function is recovered, and normally working.
The specific embodiment
Take by weighing raw material (gram) by following proportioning
Bulbus Lilii 30 Radix Curcumaes 15 Fructus Schisandrae Chinensis 10 Fructus Mori 30 Fructus Aurantii Immaturuss 12 Massa Medicata Fermentata 30 Radix Polygalaes 12 Os Draconis 30 Radix Salviae Miltiorrhizaes 15 Concha Ostreaes 30 Ramulus Uncariae Cum Uncis 10 Fructus Gardeniaes 10 Radix Glycyrrhizaes 10 Fructus Alpiniae Oxyphyllae 30 Rhizoma Alismatis 15 Concha Margaritiferas 30 Rhizoma Acori Graminei 15 Semen Glycine Germinatums 50
Above-mentioned each component is made Chinese medicine medicine decoction according to a conventional method, finishes by following step successively:
1) decoct: above-mentioned all medicines are put into marmite or rustless steel pressure cooker, add hydrology fire by 1: 2 of medicine total amount and decoct, boiled back 20 minutes, medicinal liquid is leached, 1: 1 by the medicine total amount adds the fiery decoction of the hydrology again, boils back 20 minutes, and medicinal liquid is leached;
2) bottling: seal in the disinfectant bottle in advance with packing into behind twice filtrate mixing;
3) sterilization: the medicinal liquid bottle is put into pressure cooker sterilization 20 minutes, promptly get Chinese medicine medicine decoction of the present invention.
Claims (1)
1, a kind of Chinese medicine medicine for the treatment of alcohol dependence disease is characterized in that it is the decoction of being made by the following weight proportion raw material: Bulbus Lilii 30, Radix Curcumae 15, Fructus Schisandrae Chinensis 10, Fructus Mori 30, Fructus Aurantii Immaturus 12, Massa Medicata Fermentata 30, Radix Polygalae 12, Os Draconis 30, Radix Salviae Miltiorrhizae 15, Concha Ostreae 30, Ramulus Uncariae Cum Uncis 10, Fructus Gardeniae 10, Radix Glycyrrhizae 10, Fructus Alpiniae Oxyphyllae 30, Rhizoma Alismatis 15, Concha Margaritifera 30, Rhizoma Acori Graminei 15, Semen Glycine Germinatum 50; Its preparation method is finished by following step successively: 1) decoct: above-mentioned all medicines are put into marmite or rustless steel pressure cooker, adding hydrology fire by 1: 2 of medicine total amount decocts, boiled back 20 minutes, medicinal liquid is leached, adding hydrology fire by 1: 1 of medicine total amount again decocts, boiled back 20 minutes, medicinal liquid is leached; 2) bottling: seal in the disinfectant bottle in advance with packing into behind twice filtrate mixing; 3) sterilization: the medicinal liquid bottle is put into pressure cooker sterilization 20 minutes, promptly get said Chinese medicine medicine decoction.
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| CN104621437A (en) * | 2015-01-21 | 2015-05-20 | 胡家宁 | Food for resisting alcohol dependence |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| KR100927215B1 (en) | 2008-05-29 | 2009-11-16 | 장영삼 | Alcoholic liguor additives and method for preparing the same |
| CN102008577B (en) * | 2010-12-03 | 2012-03-21 | 南方医科大学 | Drug for preventing and curing dependence of amphetamine and opiate drugs |
| CN103071087B (en) * | 2012-07-19 | 2015-01-14 | 李雪贵 | Temperance medicine |
| CN103223138A (en) * | 2013-05-21 | 2013-07-31 | 路克田 | Traditional Chinese medicine abstinent medicine |
| CN104546882B (en) * | 2014-12-30 | 2015-09-09 | 黑龙江中医药大学 | Flos Buddlejae glycosides is preparing the application in alcohol dependence medicine |
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2007
- 2007-11-09 CN CNB2007101662803A patent/CN100571766C/en not_active Expired - Fee Related
Non-Patent Citations (2)
| Title |
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| 酒依赖及其相关疾病的中医研究进展. 杜万君.中国中医药信息杂志，第10卷第增刊期. 2003 |
| 酒依赖及其相关疾病的中医研究进展. 杜万君.中国中医药信息杂志，第10卷第增刊期. 2003 * |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104621437A (en) * | 2015-01-21 | 2015-05-20 | 胡家宁 | Food for resisting alcohol dependence |
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| CN101168026A (en) | 2008-04-30 |
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