CN100566742C - The Chinese medicine preparation of treatment hyperosteogeny disease - Google Patents

Abstract

The present invention discloses a kind of Chinese medicine preparation for the treatment of hyperosteogeny disease, by Rhizoma Gastrodiae, Herba speranskiae tuberculatae, Flos Carthami, Radix Notoginseng, Rhizoma Chuanxiong, Radix Salviae Miltiorrhizae, eupolyphage sece steleophaga, Rhizoma Corydalis, Radix Gentianae Macrophyllae, Rhizoma Et Radix Notopterygii, Radix Angelicae Pubescentis, Agkistrodon, Ramulus Cinnamomi, the Cortex Eucommiae, Radix Achyranthis Bidentatae, Rhizoma Polygonati, Radix Rehmanniae Preparata, Rhizoma Cibotii, Radix Dipsaci, Radix Polygoni Multiflori (processing), Fructus Schisandrae Chinensis, Radix Ginseng, Rhizoma Cyperi, Cortex Cinnamomi, Herba Lycopodii is formed, said medicine is removed Radix Rehmanniae Preparata, outside Cortex Eucommiae viscosity is big, all the other 23 flavor Chinese medicines, take by weighing in proportion, through 100～200 order fine powders, again the Radix Rehmanniae Preparata and the Cortex Eucommiae are taken by weighing in proportion, uniform mixing, through 100～200 order fine powders, promptly obtain Chinese medicine powder of the present invention.Be pure Chinese medicinal preparation, have treating both the principal and secondary aspects of a disease, control and mend synchronous, no gastrointestinal side effect, short treating period, rapid-action, the one-time cure rate height, toxic and side effects is little, controls characteristics such as afterwards rebound phenomena is few, and expense is low.

Description

The Chinese medicine preparation of treatment hyperosteogeny disease

Technical field

The present invention discloses a kind of Chinese medicine preparation for the treatment of hyperosteogeny disease, belongs to the Chinese medicine technical field.

Technical background

At present, the oral preparation of Chinese traditional medicinal of treatment hyperosteogeny is a lot of on the medical market, and therapeutic effect varies, and most of Chinese medicine preparation all have the different gastrointestinal side effect of degree, and therapeutic effect is also unsatisfactory, cures the symptoms, not the disease, and side effect is many, and is of common occurrence.

Summary of the invention

The present invention discloses a kind of Chinese medicine preparation for the treatment of hyperosteogeny disease, is pure Chinese medicinal preparation, and is evident in efficacy, shortens treatment cycle, reduces medical expense, improves therapeutic effect, simplifies Therapeutic Method.

The present invention is according to motherland's theory of Chinese medical science, pathogenesis and Therapeutic Principle in conjunction with hyperosteogeny disease, selected pure Chinese herbal medicine with expelling wind and removing dampness, dispelling cold by warming the meridian, supporing yang activating QI, blood circulation promoting and blood stasis dispelling, suppressing the hyperactive liver the kidney invigorating, bone and muscle strengthening, benefiting QI and nourishing blood, removing obstruction in the collateral to relieve pain is made pharmaceutical preparation by traditional Chinese medicine processing technology.

Concrete medicine is formed the column weight amount umber ratio of pressing:

Rhizoma Gastrodiae 38～50, Herba speranskiae tuberculatae 30～45, Radix Notoginseng 30～45, Flos Carthami 20～35,

Rhizoma Chuanxiong 35～45, Radix Salviae Miltiorrhizae 35～45, eupolyphage sece steleophaga 15～25, Rhizoma Corydalis 20～30,

Radix Gentianae Macrophyllae 20～30, Rhizoma Et Radix Notopterygii 20～35, Radix Angelicae Pubescentis 20～35, Agkistrodon 2～3,

Ramulus Cinnamomi 18～30, the Cortex Eucommiae 25～30, Radix Achyranthis Bidentatae 18～30, Rhizoma Polygonati 20～28,

Radix Rehmanniae Preparata 20～28, Rhizoma Cibotii 18～28, Radix Dipsaci 18～28, Radix Polygoni Multiflori (processing) 20～30,

Fructus Schisandrae Chinensis 18～28, Radix Ginseng 16～24, Rhizoma Cyperi 15～25, Cortex Cinnamomi 8～15,

Herba Lycopodii 30～45.

Preferred prescription is as follows:

Rhizoma Gastrodiae 45, Herba speranskiae tuberculatae 40, Flos Carthami 30, Radix Notoginseng 35, Rhizoma Chuanxiong 40, Radix Salviae Miltiorrhizae 40,

Eupolyphage sece steleophaga 20, Rhizoma Corydalis 25, Radix Gentianae Macrophyllae 25, Rhizoma Et Radix Notopterygii 25, Radix Angelicae Pubescentis 32, Agkistrodon 3,

Ramulus Cinnamomi 20, the Cortex Eucommiae 25, Radix Achyranthis Bidentatae 20, Rhizoma Polygonati 23, Radix Rehmanniae Preparata 25, Rhizoma Cibotii 20,

Radix Dipsaci 23, Radix Polygoni Multiflori (processing) 25, Fructus Schisandrae Chinensis 20, Radix Ginseng 18, Rhizoma Cyperi 15,

Cortex Cinnamomi 12, Herba Lycopodii 33.

Concrete processing procedure: except that Radix Rehmanniae Preparata, Cortex Eucommiae viscosity were big, all the other 23 flavor Chinese medicines took by weighing in proportion with said medicine, through 100～200 order fine powders, again the Radix Rehmanniae Preparata and the Cortex Eucommiae are taken by weighing in proportion uniform mixing, through 100～200 order fine powders, promptly obtain Chinese medicine powder of the present invention.

Take by weighing by per 5～10 gram portions, once a, a twice-daily, eliminating cold for resuscitation mouth of a river clothes in the meal, 30 days is a course of treatment.

This medicated powder can also be made tablet, capsule, the watered pill, honeyed pill and granule.

Side of the present invention separates with pharmacology analysis as follows:

Medicine of the present invention mostly is the medicine of blood circulation promoting and blood stasis dispelling, expelling wind and removing dampness, suppressing the hyperactive liver and subsiding YANG, bone and muscle strengthening, wherein: Rhizoma Gastrodiae: sweet, flat, the suppressing the hyperactive liver to relieve the wind syndrome relieving convulsion; Herba speranskiae tuberculatae: hot, warm, expelling wind and removing dampness, relaxing muscles and tendons to promote blood circulation.Pain relieving, two medicines 5 are played mutually altogether: the effect of expelling wind and removing dampness, relaxing muscles and tendons and activating QI and blood in the collateral, promoting blood circulation and stopping pain, suppressing the hyperactive liver the kidney invigorating is monarch drug altogether.The shared effect that can strengthen blood circulation promoting and blood stasis dispelling, expelling wind and removing dampness, dispelling cold by warming the meridian, supporing yang activating QI, benefiting QI and nourishing blood, suppressing the hyperactive liver the kidney invigorating, bone and muscle strengthening, removing obstruction in the collateral to relieve pain of 17 flavor Chinese medicines such as Flos Carthami, Radix Notoginseng, Rhizoma Chuanxiong, Rhizoma Corydalis, Rhizoma Et Radix Notopterygii, Radix Angelicae Pubescentis, Radix Ginseng, Rhizoma Cyperi, Cortex Cinnamomi, Radix Dipsaci, Radix Polygoni Multiflori, Herba Lycopodii, Fructus Schisandrae Chinensis, Rhizoma Cibotii, the Cortex Eucommiae, Radix Rehmanniae Preparata, Agkistrodon is ministerial drug altogether.4 flavor Chinese medicines such as Radix Salviae Miltiorrhizae, eupolyphage sece steleophaga, Rhizoma Polygonati, Radix Gentianae Macrophyllae are adjuvant drug, the shared effect that can strengthen blood circulation promoting and blood stasis dispelling, removing obstruction in the collateral to relieve pain, clearing away heat-damp and promoting diuresis, life essence-filling, marrow-benefitting, benefiting QI and nourishing blood, suppressing the hyperactive liver the kidney invigorating.Radix Achyranthis Bidentatae: bitter, acid, flat, invigorating the liver and kidney, bone and muscle strengthening, eliminating blood stasis and inducing menstruation, conducting blood to flow downwards: Ramulus Cinnamomi: hot, warm, relieving the exterior syndrome by diaphoresis, warming the meridian and promoting blood circulation, supporing yang activating QI, two medicines mutually 5 increase promoting the flow of QI in the collateral by warming the meridian, blood circulation promoting and blood stasis dispelling jointly, dispel the wind and carry the effect of few, suppressing the hyperactive liver the kidney invigorating, bone and muscle strengthening, relaxing muscles and tendons and activating QI and blood in the collateral, be messenger drug altogether, play all medicine effects of guiding.

More than 25 flavor Chinese medicines shared, can reach the effect of expelling wind and removing dampness, dispelling cold by warming the meridian, supporing yang activating QI, blood circulation promoting and blood stasis dispelling, suppressing the hyperactive liver the kidney invigorating, bone and muscle strengthening, benefiting QI and nourishing blood, removing obstruction in the collateral to relieve pain.

Differential diagnosis in tcm: wind chill blockage, cold-damp resistance network, phlegm-damp intrinsic heat, qi depression to blood stasis, muscle lose and moisten foster, deficiency of qi and blood, caused by liver and kidney deficiency, kidney yang deficiency.

Indication: expelling wind and removing dampness, dispelling cold by warming the meridian, activating blood circulation and supplementing qi, removing obstruction in the collateral to relieve pain, suppressing the hyperactive liver the kidney invigorating, bone and muscle strengthening.

Be mainly used in: various hyperosteogenys, ligament calcification and rheumatism.Comprise vertebrae hyperosteogeny, intervertebral disk hernia, spinal canal stenosis, ankylosing spondylitis, gouty arthritis, ligamenta intervertebralia calcification, intervertebral foramina stenosis, mismatch of thoracis vertbra small joint, lumbar spondylolisthesis etc.Can also be used for each arthralgia that rheumatism and rheumatism cause, hyperosteogeny etc.

Good effect of the present invention is: has treating both the principal and secondary aspects of a disease, controls and mend synchronous, no gastrointestinal side effect, and short treating period, rapid-action, the one-time cure rate height, toxic and side effects is little, controls characteristics such as afterwards rebound phenomena is few, and expense is low.

For showing the therapeutic effect of medicine of the present invention, selected 104 routine patients treat with medicine of the present invention, carry out statistical analysis through system's clinical observation and are summarized as follows:

Diagnosis basis:

(1) x line, cR sheet, cT sheet, the diagnosis of MRI sheet;

(2) the various clinical symptoms of doctor trained in Western medicine case regulation.

Diagnostic criteria:

Cure: various clinical symptom disappearance.

Effectively: various clinical symptoms are obviously improved.

Invalid: various clinical symptoms do not have improvement.

The 104 routine hyperosteogeny patients that use Drug therapy of the present invention are carried out statistical analysis, cure 83 examples, cure rate is 79.9%; Produce effects 12 examples; Effective 7 examples (2 example allergy are wherein arranged); Total effective rate is 98.1%.Invalid 2 examples, inefficiency are 1.9%.

Case 1: Pan xx, man, 64 years old, cervical vertebra 3～7 joint hyperosteogenys, the ligament calcification is before the treatment: dizziness, cardiopalmus, unstable blood pressure (+), restriction of neck motion, snap (+), go up angle tenderness, radiating pain (+) in right hand numbness, the right omoplate, brachial plexus distraction test (+), pressure head test (+).Treatment back: dizziness, cardiopalmus, unstable blood pressure

(-), restriction of neck motion, snap (-) are gone up angle tenderness, radiating pain (-) in right hand numbness, the right omoplate, brachial plexus distraction test (-), pressure head test (-).

Case 2: certain man, 62 years old, cervical vertebra 3～4 joint hyperosteogenys, companion's spinal canal stenosis, before the treatment: dizzy, headache (+), cardiopalmus, breathe hard (+), unstable blood pressure (+), the cervical region activity is seriously limited, snap (+), the following sensory disturbance of cervical vertebra 3～4 pitch planes, movement disorder (+), pressure head test (+), brachial plexus distraction test (+).

The treatment back: dizzy, headache (-), cardiopalmus, breathe hard (-), unstable blood pressure (-), the cervical region activity is seriously limited, snap (-), the following sensory disturbance of cervical vertebra 3～4 pitch planes, movement disorder (-), pressure head test (-), brachial plexus distraction test (-).

Case 3: certain man, 60 years old, lumbar vertebra 3～4 internode dish bulgings, companion's lumbar vertebra 3～caudal vertebra 1 hyperosteogeny, lumbar vertebra 5～caudal vertebra 1 spinal canal stenosis.Before the treatment: deadlock in morning (+), alternately walk lamely (+), body deflection (+), the other tenderness of vertebra, radiating pain (+), waist hyperextension test (+), straight lower limb is raised and applied voltage test (+) pick-up test (+) of bending over.The treatment back: deadlock in morning (-), alternately walk lamely (-), body deflection (-), the other tenderness of vertebra, radiating pain (-), waist hyperextension test (-), straight lower limb is raised and applied voltage test (-) pick-up test (-) of bending over.

Above case was followed up a case by regular visits to after 1 year, all not recurrence.

The specific embodiment

For the ease of understanding the present invention, especially exemplified by following examples.Its effect is understood that it is to explaination of the present invention but not to any type of restriction of the present invention.

Embodiment 1

Take by weighing following medicine (unit: kilogram): Rhizoma Gastrodiae 45, Herba speranskiae tuberculatae 40, Flos Carthami 30, Radix Notoginseng 35, Rhizoma Chuanxiong 40, Radix Salviae Miltiorrhizae 40, eupolyphage sece steleophaga 20, Rhizoma Corydalis 25, Radix Gentianae Macrophyllae 25, Rhizoma Et Radix Notopterygii 25, Radix Angelicae Pubescentis 32, Agkistrodon 3, Ramulus Cinnamomi 20, the Cortex Eucommiae 25, Radix Achyranthis Bidentatae 20, Rhizoma Polygonati 23, Radix Rehmanniae Preparata 25, Rhizoma Cibotii 20, Radix Dipsaci 23, Radix Polygoni Multiflori (system) 25, Fructus Schisandrae Chinensis 20, Radix Ginseng 18, Rhizoma Cyperi 15, Cortex Cinnamomi 12, Herba Lycopodii 33.

Concrete processing procedure: except that Radix Rehmanniae Preparata, Cortex Eucommiae viscosity were big, all the other 23 flavor Chinese medicines took by weighing in proportion, through 100～200 order fine powders, the Radix Rehmanniae Preparata and the Cortex Eucommiae are taken by weighing in proportion again, and uniform mixing through 100～200 order fine powders, promptly obtains Chinese medicine powder of the present invention.

Embodiment 2

(unit: kilogram): Rhizoma Gastrodiae 38, Herba speranskiae tuberculatae 30, Flos Carthami 25, Radix Notoginseng 35, Rhizoma Chuanxiong 35, Radix Salviae Miltiorrhizae 45, eupolyphage sece steleophaga 15, Rhizoma Corydalis 20, Radix Gentianae Macrophyllae 20, Rhizoma Et Radix Notopterygii 35, Radix Angelicae Pubescentis 20, Agkistrodon 2, Ramulus Cinnamomi 30, Radix Achyranthis Bidentatae 18, Rhizoma Polygonati 20, Rhizoma Cibotii 25, Radix Dipsaci 25, Radix Polygoni Multiflori (system) 20, Fructus Schisandrae Chinensis 18, Radix Ginseng 24, Rhizoma Cyperi 25, Cortex Cinnamomi 8, Herba Lycopodii 45 are ground into 100～200 order fine powders with following medicine, with Radix Rehmanniae Preparata 20, the Cortex Eucommiae 30 uniform mixing, through 100～200 order fine powders, promptly obtain Chinese medicine powder of the present invention.

Embodiment 3

Take by weighing following medicine (unit: kilogram): Rhizoma Gastrodiae 50, Herba speranskiae tuberculatae 45, Flos Carthami 35, Radix Notoginseng 45, Rhizoma Chuanxiong 45, Radix Salviae Miltiorrhizae 35, eupolyphage sece steleophaga 25, Rhizoma Corydalis 30, Radix Gentianae Macrophyllae 30, Rhizoma Et Radix Notopterygii 20, Radix Angelicae Pubescentis 30, Agkistrodon 3, Ramulus Cinnamomi 20, the Cortex Eucommiae 28, Radix Achyranthis Bidentatae 30, Rhizoma Polygonati 28, Radix Rehmanniae Preparata 28, Rhizoma Cibotii 28, Radix Dipsaci 18, Radix Polygoni Multiflori (system) 30, Fructus Schisandrae Chinensis 28, Radix Ginseng 16, Rhizoma Cyperi 20, Cortex Cinnamomi 8, Herba Lycopodii 45.

Concrete processing procedure: except that Radix Rehmanniae Preparata, Cortex Eucommiae viscosity were big, all the other 23 flavor Chinese medicines took by weighing in proportion, through 100～200 order fine powders, the Radix Rehmanniae Preparata and the Cortex Eucommiae are taken by weighing in proportion again, and uniform mixing through 100～200 order fine powders, promptly obtains Chinese medicine powder of the present invention.

Claims (2)

1, a kind of Chinese medicine preparation for the treatment of hyperosteogeny disease is characterized in that it being to be made by following materials of weight proportions medicine:

Rhizoma Gastrodiae 38～50, Herba speranskiae tuberculatae 30～45, Radix Notoginseng 30～45, Flos Carthami 20～35,

Rhizoma Chuanxiong 35～45, Radix Salviae Miltiorrhizae 35～45, eupolyphage sece steleophaga 15～25, Rhizoma Corydalis 20～30,

Radix Gentianae Macrophyllae 20～30, Rhizoma Et Radix Notopterygii 20～35, Radix Angelicae Pubescentis 20～35, Agkistrodon 2～3,

Ramulus Cinnamomi 18～30, the Cortex Eucommiae 25～30, Radix Achyranthis Bidentatae 18～30, Rhizoma Polygonati 20～28,

Radix Rehmanniae Preparata 20～28, Rhizoma Cibotii 18～28, Radix Dipsaci 18～28, process Radix Polygoni Multiflori 20～30,

Fructus Schisandrae Chinensis 18～28, Radix Ginseng 16～24, Rhizoma Cyperi 15～25, Cortex Cinnamomi 8～15,

Herba Lycopodii 30～45.

2, Chinese medicine preparation according to claim 1 is characterized in that it being to be made by following materials of weight proportions medicine:

Rhizoma Gastrodiae 45, Herba speranskiae tuberculatae 40, Flos Carthami 30, Radix Notoginseng 35, Rhizoma Chuanxiong 40, Radix Salviae Miltiorrhizae 40,

Eupolyphage sece steleophaga 20, Rhizoma Corydalis 25, Radix Gentianae Macrophyllae 25, Rhizoma Et Radix Notopterygii 25, Radix Angelicae Pubescentis 32, Agkistrodon 3,

Ramulus Cinnamomi 20, the Cortex Eucommiae 25, Radix Achyranthis Bidentatae 20, Rhizoma Polygonati 23, Radix Rehmanniae Preparata 25, Rhizoma Cibotii 20,

Radix Dipsaci 23, process Radix Polygoni Multiflori 25, Fructus Schisandrae Chinensis 20, Radix Ginseng 18, Rhizoma Cyperi 15,

Cortex Cinnamomi 12, Herba Lycopodii 33.