CN100405921C - Health food capable of resisting fatigue - Google Patents

Health food capable of resisting fatigue Download PDF

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Publication number
CN100405921C
CN100405921C CNB2006100170633A CN200610017063A CN100405921C CN 100405921 C CN100405921 C CN 100405921C CN B2006100170633 A CNB2006100170633 A CN B2006100170633A CN 200610017063 A CN200610017063 A CN 200610017063A CN 100405921 C CN100405921 C CN 100405921C
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parts
tealeaves
health food
menthol
milk powder
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CN1907061A (en
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朱继忠
金立群
刘传贵
王福文
于永嘉
董长萍
李春燕
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HUAKANG PHARMACEUTICAL CO Ltd JILIN
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HUAKANG PHARMACEUTICAL CO Ltd JILIN
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Abstract

The invention relates to a health food against fatigue which is prepared from the following raw materials (by weight portion): ginseng saponin 5-8 parts, coffee 15-25 parts, tea 80-120 parts, white sugar 900-1000 parts, milk powder 80-120 parts, peppermint oil 2.5-6.5 parts, menthol 0.3-0.7 part.

Description

A kind of health food of antifatigue
Technical field
The invention belongs to a kind of Chinese medicine and health food.
Background technology
At present, along with the quickening of work rhythm of life, it is tired that people can feel often.In order to eliminate fatigue, can adopt usually have tea, drink coffee or eat sugar, method such as chew gum refreshes oneself, but these methods exist health care poor, act on singlely, and have tea, drink coffee and also have the inconvenient problem of carrying.
Summary of the invention
The invention provides a kind of medicine of antifatigue, serves as that to eliminate the health care that exists in the tired mode that adopts poor to solve present people, acts on single problem.The technical scheme that the present invention takes is:
Ginsenoside is the main component of genseng, and sweet the putting down of genseng flavor returned spleen, lung, the heart channel of Hang-Shaoyin, reinforces vital energy, and reinforces the spleen to benefit the lung, and promotes the production of body fluid, calms the nerves, " herbal classic " cloud: " main tonifying five zang organs, peace spirit is decided soul, ends palpitation with fear, except that perverse trend, on making eye bright, happy intelligence development." genseng can not only treat the collapse card that all diseases occur because of first deficiency of vital energy declines; Modern pharmacology studies confirm that genseng can be strengthened corticocerebral excited process, also can strengthen process of inhibition simultaneously, improves the flexibility of nervous activity process, increases work efficiency, and reduces tired; Act on hypophysis and excited hypophysis-----interrenal system, thereby strengthen the resistance of body, improve the tolerance of body high temperature or low temperature to destructive stimulus.Be equipped with tealeaves, coffee, can add the effect of strong man's excitor nerve, contain caffeine, tannic acid, vitamin and protein in the tealeaves, wherein Vit C contents is the abundantest; Coffee can irritate the brain central excitation, promotes the nerve ending activity, so tealeaves and coffee can assist a ruler in governing a country the genseng antifatigue jointly, has the effect that increases muscle power.Sugar and milk powder, it is flavor enhancement, be again nutrition, the important source of energy supplement, milk contains abundant calcium, the casein that contains lactose again, the calcium uptake is increased, and after the calcium uptake increased, the calm nervous excitation of energy, spiritual impatient disease and palpitaition were hyperfunction, can resist tealeaves again, coffee is overexcited by nervous centralis and insomnia of causing, agitation etc.Sugar is the unique heat energy that promotes the brain activity activation, also is the main heat energy of people's human body, if picked-up is not enough, fatigue will occur, comprises muscle power and mental fatigue.Peppermint does cool, returns liver, lung channel, has the sharp clearly head's effect." Tang materia medica " " main harmful wind typhoid fever, sweating bad odor, trusted subordinate's turgor, cholera, the place food does not disappear.The drink juice labor of having a bowel movement is tired." peppermint oil, menthol, the oral effect that analgesic and excited maincenter are arranged.Behavior makes medicine on the energy medicine carrying.More than all kinds of composition share, can antifatigue, increase muscle power and mental, improvement work, study energy.
The consumption of drug component of the present invention is also groped to sum up to draw through the inventor in a large number, and each amounts of components is for all having better curative effect in the following weight scope:
5~8 parts of ginsenosides, 15~25 parts of coffees, 80~120 parts of tealeaves, 900~1000 parts of white sugar, 80~120 parts of milk powder, 2.5~6.5 parts of peppermint oils, 0.3~0.7 part of menthol.
Preferably:
6 parts of ginsenosides, 20 parts of coffees, 100 parts of tealeaves, 974 parts of white sugar, 100 parts of milk powder, 4.5 parts of peppermint oils, 0.5 part of menthol.
Tealeaves is selected green tea.
Preparation method of the present invention is: with tealeaves boiling 3 times, each 15 minutes, three decocting liquids filter to merge and are concentrated to density 1.10~1.15 (60 degree are surveyed), and were standby; Other gets white sugar, and coffee is pulverized respectively with milk powder and mixed, again with the abundant mixing of ginsenoside, make particle with the tealeaves concentrated extract, sieve after the drying, peppermint oil, menthol are added ethanol dissolving back even spraying on dried granules, add a small amount of dolomol compressing tablet after the air dry.
The active component of medicine of the present invention can add various conventional auxiliary material required when preparing different dosage form, be prepared into any common formulations as disintegrant, lubricant, adhesive etc. with the method for Chinese medicinal of routine, as pill, powder, tablet, granule, capsule, oral liquid etc.
The invention has the advantages that: have the obvious anti-fatigue effect, taking convenience.
The specific embodiment
Below further set forth the beneficial effect of medicine of the present invention by testing example, these test the pharmacodynamics test that examples have comprised medicine of the present invention (hereinafter to be referred as lozenge).
Test routine lozenge pharmacodynamic study
1, material and method
1.1 animal used as test: animal portion of Beijing Medical University provides Kunming healthy adult mouse, 18~22g, approval number: moving word: the 01-3049 of doctor.
1.2 dosage is selected: 0,10,20,40 times with " lozenge " human body every day recommended intake 3.6g/60kg.bw is the dosage setting, is equivalent to " lozenge " 0,0.6,1.2,2.4g/kg.bw (be dissolved in the 10ml water and irritate stomach application liquid as " lozenge " basic, normal, high dosage group).
1.3 test rating: acute failure swimming time, blood urea nitrogen, liver glycogen and blood lactic acid after the endurance swimming in 90 minutes.
1.4 experimental technique: kunming mice is divided into 5 groups according to body weight, 30 every group, feeds and raises basal feed.Set up contrast, low, in and high dose " lozenge " group, each treated animal is further divided into 2 subgroups, 15 every group, carries out depleted swimming time and biochemical indicator respectively and measures.Control group mice every 10g body weight every day is given the 0.1ml running water, and basic, normal, high dosage group mouse is given three kinds of dosage " lozenge " filling stomach application liquid respectively every day, irritates stomach every day once, totally 4 weeks.Weigh weekly 1 time.After 4 weeks, each organizes 15 mouse of first subgroup depleted swimming time of 5% body weight determination (water temperature 30 degree) that bears a heavy burden, and each is organized 15 not swimmings with a load attached to the body of mouse of the 2nd subgroup and measures the hepatic glycogen of blood lactic acid, blood urea nitrogen (water temperature 30 is spent) after 90 minutes.
2, measurement result:
2.1 " lozenge " feeds the depleted swimming time of each dosage group chmice acute of raising group than the control group significant prolongation.See Table 1
Table 1 " lozenge " is to the influence of the depleted swimming time of mouse
Figure C20061001706300061
Difference is compared with control group in #p<0.05 conspicuousness, *Difference is compared with control group in p<0.01 highly significant.
2.290 " lozenge " each dosage group liver glycogen level increases after minute not swimming with a load attached to the body, there was a significant difference for middle dosage group.After the swimming, each dosage treated animal blood urea nitrogen level reduces than control group, and there was a significant difference for middle high dose group.Low dose group blood lactate level is lower than control group in the swimming back " lozenge ", and difference does not have conspicuousness.See Table 2
Table 2 " lozenge " is to the influence of mouse blood lactic acid, blood urea nitrogen, hepatic glycogen
Group Blood lactic acid (mg/dl) Blood urea nitrogen (mg/dl) Liver glycogen (mg/g)
Contrast ?59.7±10.2 ?39.3±4.13 ?28.1±7.25
Low dosage ?54.1±4.66 ?36.2±3.38 ?33.3±7.76
Middle dosage ?54.8±6.06 ?32.6±3.81 * ?36.0±7.40#
High dose ?70.9±13.4 ?32.8±2.91 * ?33.8±11.4
Difference is compared with control group in #p<0.05 conspicuousness, *Difference is compared with control group in p<0.01 highly significant.
3. brief summary as a result:
Per os was given mouse in continuous 28 days and is equivalent to " lozenge " submitted sample O, 0.6,1.2,2.4g/kg.bw, and " lozenge " feeds the depleted swimming time of each dosage group chmice acute of raising than the control group significant prolongation.Each dosage group liver glycogen level increases after the not swimming with a load attached to the body in 90 minutes, and there was a significant difference for middle dosage group.After the swimming, each dosage treated animal blood urea nitrogen level reduces than control group, and there was a significant difference for middle high dose group.So the present invention has antifatigue effect.
The preparation of embodiment 1 buccal tablet of the present invention
Ginsenoside 6g, coffee 20g, green tea 100g, white sugar 974g, milk powder 100g, peppermint oil 5ml, proportion are 0.900, menthol 0.5g.
Preparation method of the present invention is: with tealeaves boiling 3 times, each 15 minutes, three decocting liquids filter to merge and are concentrated to density 1.10~1.15 (60 degree are surveyed), and were standby; Other gets white sugar, and coffee is pulverized respectively with milk powder and mixed, again with the abundant mixing of ginsenoside, make particle with the tealeaves concentrated extract, sieve after the drying, peppermint oil, menthol are added ethanol dissolving back even spraying on dried granules, add a small amount of dolomol compressing tablet after the air dry.Make 1000 altogether, each sheet weight is 1.2g, contains ginsenoside 6mg in each sheet.
The preparation of embodiment 2 capsules of the present invention
Ginsenoside 5g, coffee 15g, green tea 80g, white sugar 900g, milk powder 80g, peppermint oil 3ml, proportion are 0.888, menthol 0.3g.
Preparation method of the present invention is: with tealeaves boiling 3 times, each 15 minutes, three decocting liquids filter to merge and are concentrated to density 1.10~1.15 (60 degree are surveyed), and were standby; Other gets white sugar, and coffee is pulverized respectively with milk powder and mixed, and with the abundant mixing of ginsenoside, makes particle with the tealeaves concentrated extract again, sieves after the drying, and peppermint oil, menthol are added ethanol dissolving back even spraying on dried granules, in incapsulating.
The preparation of embodiment 3 tablets of the present invention
Ginsenoside 8g, coffee 25g, tealeaves 120g, white sugar 1000g, milk powder 120g, peppermint oil 7ml, proportion are 0.908, menthol 0.7g.
Preparation method of the present invention is: with tealeaves boiling 3 times, each 15 minutes, three decocting liquids filter to merge and are concentrated to density 1.10~1.15 (60 degree are surveyed), and were standby; Other gets white sugar, and coffee is pulverized respectively with milk powder and mixed, again with the abundant mixing of ginsenoside, make particle with the tealeaves concentrated extract, sieve after the drying, peppermint oil, menthol are added ethanol dissolving back even spraying on dried granules, add a small amount of dolomol compressing tablet after the drying.

Claims (4)

1. the health food of an antifatigue is to be made by the raw material of following weight portion:
5~8 parts of ginsenosides, 15~25 parts of coffees, 80~120 parts of tealeaves, 900~1000 parts of white sugar, 80~120 parts of milk powder, 2.5~6.5 parts of peppermint oils, 0.3~0.7 part of menthol.
2. the health food of antifatigue as claimed in claim 1 is to be made by the raw material of following weight fraction:
6 parts of ginsenosides, 20 parts of coffees, 100 parts of tealeaves, 974 parts of white sugar, 100 parts of milk powder, 4.5 parts of peppermint oils, 0.5 part of menthol.
3. the preparation method of health food as claimed in claim 1 or 2 comprises the following steps:
One, with tealeaves boiling 3 times, each 15 minutes, three decocting liquids filter and merge density 1.10~1.15 when being concentrated to 60 degree surveys, and were standby;
Two, get white sugar in addition, coffee is pulverized respectively with milk powder and is mixed, and with the abundant mixing of ginsenoside, makes particle with the tealeaves concentrated extract again, sieve after the drying,
Three, peppermint oil, menthol are added ethanol dissolving back even spraying on dried granules,
4. as the preparation method of health food as described in the claim 3, also comprise the following steps:
Four, add a small amount of dolomol compressing tablet after the air dry.
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Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101890040B (en) 2010-07-27 2011-12-21 上海中药创新研究中心 Composition with anti-fatigue effect and application thereof
CN103689177B (en) * 2013-12-19 2014-12-17 刘泽源 Traditional Chinese medicine coffee beverage with health-care effect and preparation method of traditional Chinese medicine coffee beverage
CN104026243A (en) * 2014-05-19 2014-09-10 何群 Coffee milk containing fruit granules and preparation method thereof
CN108935694A (en) * 2018-06-21 2018-12-07 黑龙江飞鹤乳业有限公司 A kind of healthcare goat milk powder and preparation method thereof with antifatigue simultaneous void of enriching blood
CN110771888A (en) * 2018-07-30 2020-02-11 云南苗晨生物科技有限公司 Preparation method of edible aerosol with refreshing function
CN112868871A (en) * 2021-03-02 2021-06-01 重庆市三品功能食品研究院有限公司 Anti-radiation anti-fatigue tea buccal tablet and preparation method thereof

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1061722A (en) * 1991-09-11 1992-06-10 付殿江 The production method of instant fresh ginsheng electuary
CN1286936A (en) * 1999-09-06 2001-03-14 王树仁 New-type health food capable of refreshing and relieving fatigue
CN1608483A (en) * 2003-10-21 2005-04-27 迪沙药业集团有限公司 Sugar-free coffee meal

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1061722A (en) * 1991-09-11 1992-06-10 付殿江 The production method of instant fresh ginsheng electuary
CN1286936A (en) * 1999-09-06 2001-03-14 王树仁 New-type health food capable of refreshing and relieving fatigue
CN1608483A (en) * 2003-10-21 2005-04-27 迪沙药业集团有限公司 Sugar-free coffee meal

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