CL2022002259A1 - Anticuerpos anti-axl y composiciones - Google Patents
Anticuerpos anti-axl y composicionesInfo
- Publication number
- CL2022002259A1 CL2022002259A1 CL2022002259A CL2022002259A CL2022002259A1 CL 2022002259 A1 CL2022002259 A1 CL 2022002259A1 CL 2022002259 A CL2022002259 A CL 2022002259A CL 2022002259 A CL2022002259 A CL 2022002259A CL 2022002259 A1 CL2022002259 A1 CL 2022002259A1
- Authority
- CL
- Chile
- Prior art keywords
- compositions
- axl antibodies
- axl
- antibodies
- diseases
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2863—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against receptors for growth factors, growth regulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/21—Immunoglobulins specific features characterized by taxonomic origin from primates, e.g. man
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
- C07K2317/33—Crossreactivity, e.g. for species or epitope, or lack of said crossreactivity
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/71—Decreased effector function due to an Fc-modification
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/73—Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/74—Inducing cell proliferation
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/75—Agonist effect on antigen
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
- C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value
Abstract
La presente invención se refiere a anticuerpos anti-AXL y métodos para usarlos en el tratamiento de enfermedades y afecciones relacionadas con la actividad de AXL, por ejemplo, cáncer
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US202062982852P | 2020-02-28 | 2020-02-28 |
Publications (1)
Publication Number | Publication Date |
---|---|
CL2022002259A1 true CL2022002259A1 (es) | 2023-04-14 |
Family
ID=75426640
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CL2022002259A CL2022002259A1 (es) | 2020-02-28 | 2022-08-18 | Anticuerpos anti-axl y composiciones |
Country Status (16)
Country | Link |
---|---|
US (1) | US11807688B2 (es) |
EP (1) | EP4110824A1 (es) |
JP (1) | JP2023515821A (es) |
KR (1) | KR20220148237A (es) |
CN (1) | CN115210263A (es) |
AR (1) | AR121441A1 (es) |
AU (1) | AU2021225490A1 (es) |
BR (1) | BR112022015977A2 (es) |
CA (1) | CA3170975A1 (es) |
CL (1) | CL2022002259A1 (es) |
CO (1) | CO2022012159A2 (es) |
IL (1) | IL295596A (es) |
MX (1) | MX2022010670A (es) |
PE (1) | PE20221783A1 (es) |
TW (1) | TW202146455A (es) |
WO (1) | WO2021171257A1 (es) |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP1105427A2 (en) | 1998-08-17 | 2001-06-13 | Abgenix, Inc. | Generation of modified molecules with increased serum half-lives |
BRPI0820543A2 (pt) | 2007-11-15 | 2015-06-16 | Chugai Pharmaceutical Co Ltd | Anticorpo monoclonal capaz de ligar a anexelekto, e uso do mesmo |
RU2577986C2 (ru) | 2010-06-18 | 2016-03-20 | Дженентек, Инк. | Антитела против axl и способы их применения |
MX2017007941A (es) | 2014-12-18 | 2018-01-30 | Bergenbio Asa | Anticuerpos antagonistas anti-axl. |
JP6892431B2 (ja) * | 2015-07-10 | 2021-06-23 | ゲンマブ エー/エス | 癌治療用のaxl特異的抗体−薬物コンジュゲート |
GB201610902D0 (en) * | 2016-06-22 | 2016-08-03 | Bergen Teknologioverforing As And Bergenbio As | Anti-Axl Antagonistic Antibodies |
EP3774904A1 (en) * | 2018-04-10 | 2021-02-17 | Genmab A/S | Axl-specific antibodies for cancer treatment |
-
2021
- 2021-02-26 AR ARP210100499A patent/AR121441A1/es unknown
- 2021-02-26 IL IL295596A patent/IL295596A/en unknown
- 2021-02-26 US US17/186,465 patent/US11807688B2/en active Active
- 2021-02-26 AU AU2021225490A patent/AU2021225490A1/en active Pending
- 2021-02-26 PE PE2022001857A patent/PE20221783A1/es unknown
- 2021-02-26 BR BR112022015977A patent/BR112022015977A2/pt unknown
- 2021-02-26 JP JP2022551247A patent/JP2023515821A/ja active Pending
- 2021-02-26 EP EP21717200.6A patent/EP4110824A1/en active Pending
- 2021-02-26 WO PCT/IB2021/051636 patent/WO2021171257A1/en active Application Filing
- 2021-02-26 KR KR1020227033462A patent/KR20220148237A/ko unknown
- 2021-02-26 CA CA3170975A patent/CA3170975A1/en active Pending
- 2021-02-26 MX MX2022010670A patent/MX2022010670A/es unknown
- 2021-02-26 CN CN202180017213.3A patent/CN115210263A/zh active Pending
- 2021-03-02 TW TW110107402A patent/TW202146455A/zh unknown
-
2022
- 2022-08-18 CL CL2022002259A patent/CL2022002259A1/es unknown
- 2022-08-25 CO CONC2022/0012159A patent/CO2022012159A2/es unknown
Also Published As
Publication number | Publication date |
---|---|
PE20221783A1 (es) | 2022-11-16 |
TW202146455A (zh) | 2021-12-16 |
WO2021171257A1 (en) | 2021-09-02 |
MX2022010670A (es) | 2022-09-23 |
AR121441A1 (es) | 2022-06-08 |
CN115210263A (zh) | 2022-10-18 |
JP2023515821A (ja) | 2023-04-14 |
BR112022015977A2 (pt) | 2022-10-11 |
CA3170975A1 (en) | 2021-09-02 |
IL295596A (en) | 2022-10-01 |
US20210269532A1 (en) | 2021-09-02 |
EP4110824A1 (en) | 2023-01-04 |
US11807688B2 (en) | 2023-11-07 |
KR20220148237A (ko) | 2022-11-04 |
CO2022012159A2 (es) | 2022-10-31 |
AU2021225490A1 (en) | 2022-09-15 |
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